$169+ Cheap flights from Columbus to Panama City, FL (ECP)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/3. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — ECP
Oct 4 — Oct 111
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Columbus to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Columbus to Panama City
Cheapest
Best
Last-minute
One-way
Cheapest flights from Columbus to Panama CityExplore the most affordable flight options available from Columbus to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 4, 2026.
Explore the most affordable flight options available from Columbus to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 4, 2026.
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:00 am -
1 stop4h 35m
Thu 11/55:37 pm -
1 stop4h 53m
Deal found 9/1![Delta logo]()
$337
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:36 pm -
2 stops10h 42m
Sat 10/104:57 pm -
1 stop5h 47m
Deal found 9/1![United Airlines logo]()
$342
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2712:25 pm -
2 stops7h 00m
Tue 11/37:30 am -
2 stops8h 55m
Deal found 9/1![Southwest logo]()
$347
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/243:27 pm -
1 stop4h 15m
Sat 10/317:15 am -
1 stop4h 12m
Deal found 9/4![American Airlines logo]()
$359
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:19 pm -
1 stop3h 44m
Mon 11/211:21 am -
1 stop3h 46m
Deal found 9/3![Delta logo]()
$362
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3010:26 am -
2 stops12h 52m
Wed 10/72:08 pm -
1 stop5h 26m
Deal found 9/2![United Airlines logo]()
$367
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/54:15 pm -
2 stops8h 38m
Thu 10/86:42 pm -
1 stop4h 39m
Deal found 9/2![American Airlines logo]()
$372
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/233:10 pm -
1 stop4h 58m
Mon 9/284:35 pm -
1 stop6h 40m
Deal found 9/1![Delta logo]()
$375
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2612:43 pm -
1 stop5h 49m
Tue 9/298:29 am -
2 stops7h 57m
Deal found 9/1![American Airlines logo]()
$377
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/257:22 pm -
1 stop4h 56m
Thu 10/299:19 am -
1 stop3h 34m
Deal found 9/2![Delta logo]()
$382
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/237:03 am -
1 stop7h 10m
Mon 9/284:57 pm -
1 stop5h 47m
Deal found 9/1![United Airlines logo]()
$387
Best flights from Columbus to Panama CityDiscover carefully curated flight deals from Columbus to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 4, 2026.
Discover carefully curated flight deals from Columbus to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 4, 2026.
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:00 am -
1 stop6h 39m
Sat 10/106:00 am -
1 stop6h 06m
Deal found 9/3![Delta logo]()
$337
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/311:50 am -
2 stops9h 40m
Tue 11/107:55 am -
1 stop3h 35m
Deal found 9/2![Southwest logo]()
$342
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:17 am -
2 stops9h 56m
Sat 10/313:05 pm -
1 stop7h 39m
Deal found 9/4![United Airlines logo]()
$398
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:22 pm -
1 stop4h 56m
Wed 10/1411:21 am -
1 stop5h 48m
Deal found 9/3![Delta logo]()
$362
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/255:40 am -
2 stops9h 10m
Sat 10/317:40 am -
2 stops8h 40m
Deal found 9/3![Southwest logo]()
$392
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:19 pm -
1 stop3h 44m
Mon 11/211:21 am -
1 stop3h 46m
Deal found 9/3![Delta logo]()
$362
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:22 pm -
1 stop4h 56m
Mon 10/196:20 pm -
1 stop5h 24m
Deal found 9/1![Delta logo]()
$362
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/52:31 pm -
1 stop6h 22m
Mon 11/96:55 pm -
1 stop4h 35m
Deal found 9/3![Delta logo]()
$375
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/257:22 pm -
1 stop4h 56m
Thu 10/299:19 am -
1 stop3h 34m
Deal found 9/1![Delta logo]()
$382
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2111:15 am -
1 stop3h 40m
Sun 10/256:20 pm -
1 stop5h 24m
Deal found 9/1![Delta logo]()
$382
This Delta deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:22 pm -
1 stop4h 56m
Fri 10/236:20 pm -
1 stop5h 24m
Deal found 8/30![Delta logo]()
$413
This Delta deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/311:15 am -
1 stop5h 16m
Mon 10/54:35 pm -
1 stop6h 40m
Deal found 9/4![Delta logo]()
$413
Last-minute flights from Columbus to Panama CityDiscover last-minute flight deals from Columbus to Panama City. Data last updated September 4, 2026 and is based on user searches.
Discover last-minute flight deals from Columbus to Panama City. Data last updated September 4, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/233:10 pm -
1 stop4h 58m
Mon 9/284:35 pm -
1 stop6h 40m
Deal found 9/1![Delta logo]()
$375
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/237:03 am -
1 stop7h 10m
Mon 9/284:57 pm -
1 stop5h 47m
Deal found 9/1![United Airlines logo]()
$387
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2612:43 pm -
1 stop5h 49m
Tue 9/298:29 am -
2 stops7h 57m
Deal found 9/1![American Airlines logo]()
$377
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3010:26 am -
2 stops12h 52m
Wed 10/72:08 pm -
1 stop5h 26m
Deal found 9/2![United Airlines logo]()
$367
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:36 pm -
2 stops10h 42m
Sat 10/104:57 pm -
1 stop5h 47m
Deal found 9/1![United Airlines logo]()
$342
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/54:15 pm -
2 stops8h 38m
Thu 10/86:42 pm -
1 stop4h 39m
Deal found 9/2![American Airlines logo]()
$372
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/243:27 pm -
1 stop4h 15m
Sat 10/317:15 am -
1 stop4h 12m
Deal found 9/4![American Airlines logo]()
$359
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/257:22 pm -
1 stop4h 56m
Thu 10/299:19 am -
1 stop3h 34m
Deal found 9/2![Delta logo]()
$382
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:00 am -
1 stop4h 35m
Thu 11/55:37 pm -
1 stop4h 53m
Deal found 9/1![Delta logo]()
$337
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2712:25 pm -
2 stops7h 00m
Tue 11/37:30 am -
2 stops8h 55m
Deal found 9/1![Southwest logo]()
$347
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:19 pm -
1 stop3h 44m
Mon 11/211:21 am -
1 stop3h 46m
Deal found 9/3![Delta logo]()
$362
One-way flights from Columbus to Panama CitySearch for one-way flight options from Columbus to Panama City. Find affordable one-way fares based on user searches. Data last updated September 4, 2026.
Search for one-way flight options from Columbus to Panama City. Find affordable one-way fares based on user searches. Data last updated September 4, 2026.
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/311:15 am -
1 stop5h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Delta logo]()
$169
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:20 am -
2 stops9h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![United Airlines logo]()
$174
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/111:50 am -
2 stops9h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Southwest logo]()
$179
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:19 pm -
1 stop3h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Delta logo]()
$194
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:42 pm -
1 stop5h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![American Airlines logo]()
$197
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/210:26 am -
2 stops12h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![United Airlines logo]()
$199
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/35:15 am -
2 stops12h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![United Airlines logo]()
$202
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:00 am -
1 stop5h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Delta logo]()
$204
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:19 pm -
1 stop5h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Delta logo]()
$207
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:10 am -
1 stop5h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/1![United Airlines logo]()
$209
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/229:03 am -
2 stops9h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 8/31![American Airlines logo]()
$212
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/13:30 pm -
1 stop6h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/1![Southwest logo]()
$214
Find flight deals from Columbus to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Columbus (C01) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 4, 2026.
Round-trip from | $337 (Delta) |
|---|---|
One-way from | $169 (Delta) |
Popular in | December |
Cheapest in | September |
Average price | $348 |
Cheapflights Fare Finder
Customize your flight search to find flights from Columbus to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 4, 2026.
Use the filters below to find and compare flights from Columbus to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ColumbusPanama City
CMH Columbus - ECP Panama City NW Florida Beaches
CMHECP
Columbus
Wed 12/2
7:05 pm-11:17 pm
1 stop5h 12m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$169
ColumbusPanama City
CMH Columbus - ECP Panama City NW Florida Beaches
CMHECP
Columbus
Sat 9/26
6:30 am-11:06 am
1 stop5h 36m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$169
ColumbusPanama City
CMH Columbus - ECP Panama City NW Florida Beaches
CMHECP
Columbus
Mon 11/2
6:00 am-10:35 am
1 stop5h 35m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$169
ColumbusPanama City
CMH Columbus - ECP Panama City NW Florida Beaches
CMHECP
Columbus
Thu 12/3
5:47 pm-8:55 pm
1 stop4h 08m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$169
ColumbusPanama City
CMH Columbus - ECP Panama City NW Florida Beaches
CMHECP
Columbus
Wed 12/2
5:15 am-12:37 pm
2 stops8h 22m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$174
ColumbusPanama City
CMH Columbus - ECP Panama City NW Florida Beaches
CMHECP
Columbus
Fri 11/27
6:00 am-9:09 am
1 stop4h 09m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$194
ColumbusPanama City
CMH Columbus - ECP Panama City NW Florida Beaches
CMHECP
Columbus
Fri 10/2
6:00 am-10:34 am
1 stop5h 34m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$204
ColumbusPanama City
CMH Columbus - ECP Panama City NW Florida Beaches
CMHECP
Columbus
Fri 10/16
7:22 pm-11:18 pm
1 stop4h 56m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$207
Quickest round-trip
ColumbusPanama City
CMH Columbus - ECP Panama City NW Florida Beaches
CMHECP
Columbus
Fri 11/6
5:19 pm-7:53 pm
1 stop3h 34m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$207
ColumbusPanama City
CMH Columbus - ECP Panama City NW Florida Beaches
CMHECP
Columbus
Sat 10/3
7:00 am-12:39 pm
1 stop6h 39m
Panama City NW Florida Beaches
Sat 10/10
6:00 am-1:06 pm
1 stop6h 06m
$337
Showing 1-10 of 21 resultsSorted by cheapest first
Best time to book a flight from Columbus to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Columbus with our price prediction graph.
C01-ECP
CMH-ECP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Columbus to Panama City
C01-ECP
CMH-ECP
What is the cheapest month to book a flight from Columbus to Panama City, Florida?
Currently, September is the cheapest month in which you can book a flight from Columbus to Panama City, Florida (average of $348). Flying from Columbus to Panama City, Florida in December is currently the most expensive (average of $484). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Columbus to Panama City, Florida?
Airfare is typical for this route at the moment.
Columbus to Panama City, Florida flights typically cost between $304 and $427 in October.The cheapest round-trip price found within the last 5 days was $337 on Delta (Oct 27-Oct 31).
How far ahead should I book a flight from Columbus to Panama City, Florida?
Booking 42 days in advance of your planned departure date is, on average, the best time to get cheap flights from Columbus to Panama City, Florida. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 4, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Columbus to Panama City have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.5
Overall
8.0
Food
7.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Boarding
8.1
Entertainment
7.5
Overall
8.0
Food
7.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Boarding
8.1
Entertainment
7.5
Overall
8.0
Food
7.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Boarding
8.1
Entertainment
7.5
Overall
8.0
Food
7.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Boarding
8.1
Entertainment
7.5
Overall
8.0
Food
7.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Related info for your journey
Find useful and relevant information for your journey from Columbus to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Panama City?
Book flights to Panama City if you plan to visit one of these locationsMexico Beach
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Panama City flight routes
Popular flights
Top destinations
Alternative routes for Columbus to Panama City
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama City by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Columbus to Panama City by cabin class
Find flights from Columbus to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Columbus and Panama City flights
Browse other Columbus and Panama City flight options. Last updated on September 4, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 4, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Columbus to Panama City flights
Consider these flights traveling from Columbus to Panama City.
Top 4 airlines flying from Columbus to Panama City
Discover the top 4 airlines that operate flights from Columbus to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$246 | Average$411 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$263 | Average$385 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$288 | Average$321 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$309 | Average$435 | FlexibilityNo cancel fee | On-time63% |