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Panama City

$135+ Cheap flights from Colorado to Panama City, FL (ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/25. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — ECP
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Cheap flight deals from Colorado to Panama City

Keep the following information in mind while searching for Colorado to Panama City flight deals. Data was last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$269
(American Airlines)

One-way from

$135
(Delta)

Popular in

December

Cheapest in

August

Average price

$440

Good round-trip deal

$329 or less
Provider with most accurate pricing for Denver Intl-Panama City NW Florida Beaches flight deals.
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Provider most trusted by Cheapflights users for Denver Intl-Panama City NW Florida Beaches flights.
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From Colorado to Panama City NW Florida Beaches
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One-way flight from Colorado to Panama City NW Florida Beaches
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High demand for flights, 1% potential price rise
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Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Price to beat on a round-trip flight from Colorado to Panama City NW Florida Beaches.
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Find flight deals from Colorado to Panama City

Cheapest flights from Colorado to Panama City
Explore the most affordable flight options available from Colorado to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/106:00 amDEN - ECP
1 stop5h 21mAmerican Airlines
Mon 12/153:18 pmECP - DEN
1 stop8h 04mAmerican Airlines
Deal found 10/28$269
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/136:47 amDEN - ECP
1 stop6h 20mAmerican Airlines
Thu 11/2011:04 amECP - DEN
1 stop9h 02mAmerican Airlines
Deal found 10/27$289
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/95:50 amGJT - ECP
2 stops30h 15mDelta
Sat 12/1310:00 amECP - GJT
2 stops13h 47mDelta
Deal found 10/28$296
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1612:50 amDEN - ECP
1 stop6h 45mDelta
Thu 11/201:32 pmECP - DEN
1 stop5h 19mDelta
Deal found 10/28$299
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/121:10 pmDEN - ECP
1 stop4h 50mDelta
Sat 11/156:00 amECP - DEN
1 stop8h 00mDelta
Deal found 10/28$309
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1210:24 amDEN - ECP
1 stop7h 52mAmerican Airlines
Sat 11/157:15 amECP - DEN
2 stops11h 30mAmerican Airlines
Deal found 10/28$314
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/127:05 amDEN - ECP
1 stop4h 42mDelta
Sun 11/164:26 pmECP - DEN
1 stop8h 36mDelta
Deal found 10/27$329
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/131:42 pmCOS - ECP
1 stop5h 50mDelta
Mon 11/171:32 pmECP - COS
1 stop8h 08mDelta
Deal found 10/29$329
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/197:49 amDEN - ECP
1 stop7h 55mAmerican Airlines
Tue 12/23:22 pmECP - DEN
1 stop8h 03mAmerican Airlines
Deal found 10/28$344
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/273:14 pmDEN - ECP
1 stop6h 53mDelta
Tue 12/21:45 pmECP - DEN
1 stop20h 30mDelta
Deal found 10/27$346
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/226:30 amDEN - ECP
1 stop8h 05mSouthwest
Mon 12/295:55 pmECP - DEN
1 stop6h 10mSouthwest
Deal found 10/27$358
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/61:39 pmDRO - ECP
2 stops7h 10mUnited Airlines
Wed 12/1011:05 amECP - DRO
2 stops10h 29mUnited Airlines
Deal found 10/28$359

Cheapflights Fare Finder

 
Customize your flight search to find flights from Colorado to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Colorado to Panama City that are best for you.

Fly from

Colorado

Fly to

Panama City

Route

Depart

Return

Price

DenverPanama City

DEN - ECP

DENECP

Denver Intl

Wed 1/14

6:00 am-12:47 pm

1 stop5h 47m

Panama City NW Florida Beaches

Sat 1/17

5:14 pm-11:01 pm

1 stop6h 47m

$269

DenverPanama City

DEN - ECP

DENECP

Denver Intl

Tue 1/13

5:01 am-12:02 pm

1 stop6h 01m

Panama City NW Florida Beaches

Sat 1/17

1:10 pm-7:55 pm

1 stop7h 45m

$269

Colorado SpringsPanama City

COS - ECP

COSECP

Colorado Springs

Sat 1/17

1:21 pm-7:50 pm

1 stop5h 29m

Panama City NW Florida Beaches

Mon 1/26

7:18 am-12:23 pm

1 stop6h 05m

$269

Colorado SpringsPanama City

COS - ECP

COSECP

Colorado Springs

Thu 1/22

1:20 pm-7:50 pm

1 stop5h 30m

Panama City NW Florida Beaches

Thu 1/29

7:18 am-12:23 pm

1 stop6h 05m

$269

Colorado SpringsPanama City

COS - ECP

COSECP

Colorado Springs

Sat 1/17

1:21 pm-7:50 pm

1 stop5h 29m

Panama City NW Florida Beaches

Fri 1/23

7:18 am-12:23 pm

1 stop6h 05m

$269

Colorado SpringsPanama City

COS - ECP

COSECP

Colorado Springs

Tue 2/24

1:40 pm-10:42 pm

1 stop8h 02m

Panama City NW Florida Beaches

Wed 2/25

7:45 am-1:05 pm

1 stop6h 20m

$269

Colorado SpringsPanama City

COS - ECP

COSECP

Colorado Springs

Sun 1/18

1:21 pm-7:53 pm

1 stop5h 32m

Panama City NW Florida Beaches

Fri 1/23

7:18 am-12:23 pm

1 stop6h 05m

$269

Colorado SpringsPanama City

COS - ECP

COSECP

Colorado Springs

Thu 1/22

1:20 pm-7:50 pm

1 stop5h 30m

Panama City NW Florida Beaches

Wed 1/28

6:00 am-12:23 pm

1 stop7h 23m

$269

Colorado SpringsPanama City

COS - ECP

COSECP

Colorado Springs

Sat 1/17

7:59 am-10:55 pm

2 stops13h 56m

Panama City NW Florida Beaches

Thu 1/29

6:00 am-12:23 pm

1 stop7h 23m

$274

Colorado SpringsPanama City

COS - ECP

COSECP

Colorado Springs

Sat 1/17

7:59 am-7:50 pm

2 stops10h 51m

Panama City NW Florida Beaches

Tue 1/27

7:18 am-12:23 pm

1 stop6h 05m

$274

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 51 results
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Best time to book a flight from Colorado to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Colorado with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Colorado to Panama City

What is the cheapest month to book a flight from Colorado to Panama City, Florida?

Currently, November is the cheapest month in which you can book a flight from Colorado to Panama City, Florida (average of $108). Flying from Colorado to Panama City, Florida in March is currently the most expensive (average of $171). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CO to ECP?

Find hourly flight availability from Colorado to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 29, 2025.

It’s typically best to fly out from Colorado to Panama City, Florida in the evening. Doing so could potentially save you 28% on the flight price compared to flying in the afternoon, which is usually more expensive.

Related info for your journey

Find useful and relevant information for your journey from Colorado to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Colorado?

    Panama City NW Florida Beaches (ECP) is the airport you will fly into if you book a flight from Colorado to Panama City. It is only a 16.0 mi journey from NW Florida Beaches (ECP) to Panama City’s city center.

  • How long is the flight from Colorado to Panama City, Florida?

    Departing from Colorado to Panama City, Florida will take you 5h 47m. Airlines will cover a distance of 1248 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Colorado to Panama City, Florida one-way?

    One-way options have recently been found by users for as low as $135 on Southwest. Other airlines that offer cheap prices include Delta from $135 and American Airlines from $155 one-way.

  • What are the most popular routes from Colorado to Panama City, Florida?

    While some choose either Colorado Springs - Panama City NW Florida Beaches or Grand Junction Regnl - Panama City NW Florida Beaches, Denver Intl - Panama City NW Florida Beaches is the most popular route from Colorado to Panama City, Florida.

  • What are the most reliable airlines from Colorado to Panama City, Florida?

    The top 3 most reliable airlines when flying from Colorado to Panama City, Florida are Southwest (100%), United Airlines (94%) and SkyWest Airlines (88%).

  • What are the cheapest flights from Colorado to Panama City, Florida?

    The cheapest flight price from Colorado to Panama City, Florida is $249. On average you can expect to pay $447. The most popular route, (Denver Intl - Panama City NW Florida Beaches), can usually be booked for $269.

  • Can I find deals for flights from Colorado to Panama City that include hotel bookings?

    Yes. In addition to deals on Colorado to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Colorado to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Colorado to Panama City.

  • Can I find deals for business class flights from Colorado to Panama City?

    Yes. Cheapflights offers flight deals from Colorado to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Colorado to Panama City, Florida?

    Currently, November is the cheapest month in which you can book a flight from Colorado to Panama City, Florida (average of $108). Flying from Colorado to Panama City, Florida in March is currently the most expensive (average of $171). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Mexico Beach

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Alternative routes for Colorado to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Colorado to Panama City

Discover the top 4 airlines that operate flights from Colorado to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$204Average$374FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$252Average$436FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$261Average$480FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$284Average$457FlexibilityNo cancel feeOn-time69%

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