$144+ Cheap flights from Charleston to Panama City, FL (CHS - ECP)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/19. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — ECP
May 17 — May 241
Round-trip
1 adult, Economy
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Cheapest flights from Charleston to Panama CityExplore the most affordable flight options available from Charleston to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2026.
Explore the most affordable flight options available from Charleston to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2026.
This Delta deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:15 am
CHS
- ECP
1 stop3h 15m
Delta
Wed 5/206:00 am
ECP
- CHS
1 stop5h 10m
Delta
Deal found 4/13![Delta logo]()
$287
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:03 pm
CHS
- ECP
1 stop6h 25m
Delta
Tue 6/97:46 am
ECP
- CHS
1 stop3h 18m
Delta
Deal found 4/15![Delta logo]()
$341
This American Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/138:21 pm
CHS
- ECP
1 stop4h 25m
American Airlines
Wed 5/2010:50 am
ECP
- CHS
2 stops12h 34m
American Airlines
Deal found 4/13![American Airlines logo]()
$342
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/512:58 pm
CHS
- ECP
1 stop6h 28m
American Airlines
Tue 6/97:05 am
ECP
- CHS
2 stops10h 46m
American Airlines
Deal found 4/15![American Airlines logo]()
$346
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/78:21 pm
CHS
- ECP
1 stop4h 25m
American Airlines
Wed 5/137:21 am
ECP
- CHS
1 stop5h 49m
American Airlines
Deal found 4/14![American Airlines logo]()
$353
This American Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/287:50 pm
CHS
- ECP
1 stop4h 50m
American Airlines
Sat 5/306:45 pm
ECP
- CHS
1 stop4h 14m
American Airlines
Deal found 4/13![American Airlines logo]()
$360
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/148:21 pm
CHS
- ECP
1 stop4h 25m
American Airlines
Mon 5/187:21 am
ECP
- CHS
1 stop5h 49m
American Airlines
Deal found 4/15![American Airlines logo]()
$365
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1612:40 pm
CHS
- ECP
1 stop6h 10m
Southwest
Sat 5/237:20 am
ECP
- CHS
2 stops11h 55m
Southwest
Deal found 4/16![Southwest logo]()
$370
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/1512:00 pm
CHS
- ECP
2 stops10h 40m
Southwest
Tue 6/307:40 am
ECP
- CHS
1 stop4h 30m
Southwest
Deal found 4/15![Southwest logo]()
$371
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:15 am
CHS
- ECP
2 stops8h 00m
Southwest
Tue 6/97:00 am
ECP
- CHS
2 stops8h 10m
Southwest
Deal found 4/15![Southwest logo]()
$376
Best flights from Charleston to Panama CityDiscover carefully curated flight deals from Charleston to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 17, 2026.
Discover carefully curated flight deals from Charleston to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 17, 2026.
This Delta deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:15 am
CHS
- ECP
1 stop3h 15m
Delta
Wed 5/206:00 am
ECP
- CHS
1 stop5h 10m
Delta
Deal found 4/13![Delta logo]()
$287
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/1512:00 pm
CHS
- ECP
2 stops10h 40m
Southwest
Tue 6/307:00 am
ECP
- CHS
2 stops12h 25m
Southwest
Deal found 4/15![Southwest logo]()
$376
This American Airlines deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1212:58 pm
CHS
- ECP
1 stop3h 48m
American Airlines
Mon 6/157:05 am
ECP
- CHS
1 stop4h 03m
American Airlines
Deal found 4/12![American Airlines logo]()
$395
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/158:20 am
CHS
- ECP
1 stop5h 06m
Delta
Tue 6/306:00 am
ECP
- CHS
1 stop3h 18m
Delta
Deal found 4/15![Delta logo]()
$341
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:15 am
CHS
- ECP
2 stops8h 00m
Southwest
Tue 6/97:00 am
ECP
- CHS
2 stops8h 10m
Southwest
Deal found 4/15![Southwest logo]()
$376
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/12:30 pm
CHS
- ECP
1 stop5h 30m
Southwest
Tue 8/47:45 am
ECP
- CHS
2 stops10h 30m
Southwest
Deal found 4/15![Southwest logo]()
$380
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/126:15 am
CHS
- ECP
1 stop3h 05m
Delta
Fri 7/171:36 pm
ECP
- CHS
1 stop4h 18m
Delta
Deal found 4/14![Delta logo]()
$395
This Delta deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/45:30 am
CHS
- ECP
1 stop3h 45m
Delta
Mon 9/77:05 pm
ECP
- CHS
1 stop3h 52m
Delta
Deal found 4/12![Delta logo]()
$395
This Southwest deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:35 am
CHS
- ECP
1 stop7h 30m
Southwest
Sun 9/135:50 am
ECP
- CHS
1 stop7h 35m
Southwest
Deal found 4/12![Southwest logo]()
$400
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/35:30 am
CHS
- ECP
1 stop3h 45m
Delta
Sun 9/67:45 am
ECP
- CHS
1 stop5h 02m
Delta
Deal found 4/14![Delta logo]()
$395
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/152:15 pm
CHS
- ECP
1 stop5h 05m
Southwest
Sun 5/175:35 am
ECP
- CHS
1 stop10h 55m
Southwest
Deal found 4/15![Southwest logo]()
$400
Last-minute flights from Charleston to Panama CityDiscover last-minute flight deals from Charleston to Panama City. Data last updated April 17, 2026 and is based on user searches.
Discover last-minute flight deals from Charleston to Panama City. Data last updated April 17, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/78:21 pm
CHS
- ECP
1 stop4h 25m
American Airlines
Wed 5/137:21 am
ECP
- CHS
1 stop5h 49m
American Airlines
Deal found 4/14![American Airlines logo]()
$353
This Southwest deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/112:15 pm
CHS
- ECP
1 stop5h 05m
Southwest
Mon 5/186:40 am
ECP
- CHS
2 stops8h 30m
Southwest
Deal found 4/13![Southwest logo]()
$397
This Delta deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:15 am
CHS
- ECP
1 stop3h 15m
Delta
Wed 5/206:00 am
ECP
- CHS
1 stop5h 10m
Delta
Deal found 4/13![Delta logo]()
$287
This American Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/138:21 pm
CHS
- ECP
1 stop4h 25m
American Airlines
Wed 5/2010:50 am
ECP
- CHS
2 stops12h 34m
American Airlines
Deal found 4/13![American Airlines logo]()
$342
This Southwest deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/137:15 am
CHS
- ECP
2 stops12h 40m
Southwest
Wed 5/207:55 am
ECP
- CHS
2 stops11h 05m
Southwest
Deal found 4/13![Southwest logo]()
$391
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/148:21 pm
CHS
- ECP
1 stop4h 25m
American Airlines
Thu 5/214:16 pm
ECP
- CHS
1 stop6h 43m
American Airlines
Deal found 4/15![American Airlines logo]()
$365
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1612:40 pm
CHS
- ECP
1 stop6h 10m
Southwest
Sat 5/237:20 am
ECP
- CHS
2 stops11h 55m
Southwest
Deal found 4/16![Southwest logo]()
$370
This American Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/287:50 pm
CHS
- ECP
1 stop4h 50m
American Airlines
Sat 5/306:45 pm
ECP
- CHS
1 stop4h 14m
American Airlines
Deal found 4/13![American Airlines logo]()
$360
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/283:20 pm
CHS
- ECP
1 stop4h 06m
American Airlines
Sun 5/316:45 pm
ECP
- CHS
1 stop4h 14m
American Airlines
Deal found 4/14![American Airlines logo]()
$395
This Southwest deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/281:15 pm
CHS
- ECP
2 stops9h 25m
Southwest
Sat 5/307:20 am
ECP
- CHS
2 stops10h 15m
Southwest
Deal found 4/13![Southwest logo]()
$396
One-way flights from Charleston to Panama CitySearch for one-way flight options from Charleston to Panama City. Find affordable one-way fares based on user searches. Data last updated April 17, 2026.
Search for one-way flight options from Charleston to Panama City. Find affordable one-way fares based on user searches. Data last updated April 17, 2026.
This American Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/197:39 pm
CHS
- ECP
1 stop4h 13m
American Airlines
Deal found 4/13![American Airlines logo]()
$144
This Southwest deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/197:40 am
CHS
- ECP
2 stops12h 15m
Southwest
Deal found 4/13![Southwest logo]()
$180
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:59 pm
CHS
- ECP
1 stop4h 29m
Delta
Deal found 4/16![Delta logo]()
$183
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/78:05 am
CHS
- ECP
2 stops12h 45m
Southwest
Deal found 4/16![Southwest logo]()
$245
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/307:44 pm
CHS
- ECP
1 stop4h 28m
Delta
Deal found 4/15![Delta logo]()
$259
This Delta deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:20 am
CHS
- ECP
1 stop5h 55m
Delta
Deal found 4/12![Delta logo]()
$331
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:00 am
CHS
- ECP
2 stops11h 15m
Southwest
Deal found 4/15![Southwest logo]()
$335
This Southwest deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2212:00 pm
CHS
- ECP
2 stops9h 45m
Southwest
Deal found 4/12![Southwest logo]()
$336
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/710:15 am
CHS
- ECP
3 stops28h 03m
United Airlines
Deal found 4/16![United Airlines logo]()
$631
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/305:07 pm
CHS
- ECP
3 stops21h 11m
United Airlines
Deal found 4/15![United Airlines logo]()
$639
This United Airlines deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:00 am
CHS
- ECP
3 stops28h 38m
United Airlines
Deal found 4/12![United Airlines logo]()
$719
Find flight deals from Charleston to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $287 (Delta) |
One-way from | $144 (American Airlines) |
Popular in | April |
Cheapest in | August |
Average price | $707 |
Cheapflights Fare Finder
Customize your flight search to find flights from Charleston to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2026.
Use the filters below to find and compare flights from Charleston to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonPanama City
CHS - ECP
CHSECP
Charleston
Wed 5/13
6:15 am-8:30 am
1 stop3h 15m
Panama City NW Florida Beaches
Wed 5/20
6:00 am-12:10 pm
1 stop5h 10m
$287
CharlestonPanama City
CHS - ECP
CHSECP
Charleston
Mon 6/15
8:20 am-12:26 pm
1 stop5h 06m
Panama City NW Florida Beaches
Tue 6/30
6:00 am-10:18 am
1 stop3h 18m
$341
CharlestonPanama City
CHS - ECP
CHSECP
Charleston
Mon 6/15
12:00 pm-9:40 pm
2 stops10h 40m
Panama City NW Florida Beaches
Tue 6/30
7:00 am-8:25 pm
2 stops12h 25m
$376
CharlestonPanama City
CHS - ECP
CHSECP
Charleston
Fri 6/5
7:15 am-2:15 pm
2 stops8h 00m
Panama City NW Florida Beaches
Tue 6/9
7:00 am-4:10 pm
2 stops8h 10m
$376
CharlestonPanama City
CHS - ECP
CHSECP
Charleston
Sat 8/1
2:30 pm-7:00 pm
1 stop5h 30m
Panama City NW Florida Beaches
Tue 8/4
7:45 am-7:15 pm
2 stops10h 30m
$380
CharlestonPanama City
CHS - ECP
CHSECP
Charleston
Fri 6/12
12:58 pm-3:46 pm
1 stop3h 48m
Panama City NW Florida Beaches
Mon 6/15
7:05 am-12:08 pm
1 stop4h 03m
$395
Quickest round-trip
CharlestonPanama City
CHS - ECP
CHSECP
Charleston
Sun 7/12
6:15 am-8:20 am
1 stop3h 05m
Panama City NW Florida Beaches
Fri 7/17
1:36 pm-6:54 pm
1 stop4h 18m
$395
CharlestonPanama City
CHS - ECP
CHSECP
Charleston
Fri 9/4
5:30 am-8:15 am
1 stop3h 45m
Panama City NW Florida Beaches
Mon 9/7
7:05 pm-11:57 pm
1 stop3h 52m
$395
CharlestonPanama City
CHS - ECP
CHSECP
Charleston
Thu 9/3
5:30 am-8:15 am
1 stop3h 45m
Panama City NW Florida Beaches
Sun 9/6
7:45 am-1:47 pm
1 stop5h 02m
$395
CharlestonPanama City
CHS - ECP
CHSECP
Charleston
Fri 9/11
6:35 am-1:05 pm
1 stop7h 30m
Panama City NW Florida Beaches
Sun 9/13
5:50 am-2:25 pm
1 stop7h 35m
$400
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from Charleston to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charleston to Panama City in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Charleston-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Charleston-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Charleston-Panama City, Florida flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Charleston-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Charleston to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Charleston with our price prediction graph.
CHS-ECP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Charleston to Panama City
What is the cheapest month to book a flight from Charleston to Panama City, Florida?
Currently, August is the cheapest month in which you can book a flight from Charleston to Panama City, Florida (average of $301). Flying from Charleston to Panama City, Florida in April is currently the most expensive (average of $707). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Charleston to Panama City, Florida?
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated April 17, 2026.
Read reviews from past customers who have flown Delta and American Airlines from Charleston to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Comfort
7.9
Boarding
8.1
Overall
7.9
Food
7.2
Crew
8.5
Reviews
1 / 20
8.0
ExcellentMatthew,Oct 2025
GSP - ATL
Entertainment
7.8
Comfort
7.9
Boarding
8.1
Overall
7.9
Food
7.2
Crew
8.5
Reviews
1 / 20
8.0
ExcellentMatthew,Oct 2025
GSP - ATL
Entertainment
7.8
Comfort
7.9
Boarding
8.1
Overall
7.9
Food
7.2
Crew
8.5
Reviews
1 / 20
8.0
ExcellentMatthew,Oct 2025
GSP - ATL
Related info for your journey
Find useful and relevant information for your journey from Charleston to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Panama City?
Book flights to Panama City if you plan to visit one of these locationsMexico Beach
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Complete your trip
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Charleston and Panama City flights
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Top 2 airlines flying from Charleston to Panama City
Discover the top 2 airlines that operate flights from Charleston to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$231 | Average$387 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$272 | Average$368 | FlexibilityNo cancel fee | On-time71% |