$156+ Cheap flights from Charleston to Panama City, FL (CHS - ECP)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/29. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — ECP
May 10 — May 171
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Charleston to Panama City
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Best
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Cheapest flights from Charleston to Panama CityExplore the most affordable flight options available from Charleston to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 10, 2026.
Explore the most affordable flight options available from Charleston to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 10, 2026.
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/211:15 am
CHS
- ECP
1 stop7h 35m
Southwest
Sat 5/97:20 am
ECP
- CHS
1 stop3h 40m
Southwest
Deal found 4/7![Southwest logo]()
$311
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/512:00 pm
CHS
- ECP
2 stops9h 45m
Southwest
Tue 5/127:15 am
ECP
- CHS
2 stops10h 20m
Southwest
Deal found 4/7![Southwest logo]()
$321
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:03 pm
CHS
- ECP
1 stop6h 25m
Delta
Sun 6/76:00 am
ECP
- CHS
1 stop3h 18m
Delta
Deal found 4/6![Delta logo]()
$353
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/211:15 am
CHS
- ECP
1 stop7h 35m
Southwest
Fri 5/89:55 am
ECP
- CHS
2 stops10h 35m
Southwest
Deal found 4/8![Southwest logo]()
$358
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/283:20 pm
CHS
- ECP
1 stop4h 06m
American Airlines
Sun 5/316:45 pm
ECP
- CHS
1 stop4h 14m
American Airlines
Deal found 4/5![American Airlines logo]()
$373
This American Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:18 pm
CHS
- ECP
1 stop6h 22m
American Airlines
Sun 6/77:05 am
ECP
- CHS
1 stop4h 19m
American Airlines
Deal found 4/9![American Airlines logo]()
$383
This Delta deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:15 am
CHS
- ECP
1 stop2h 59m
Delta
Mon 6/156:41 pm
ECP
- CHS
1 stop3h 43m
Delta
Deal found 4/9![Delta logo]()
$395
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/281:15 pm
CHS
- ECP
2 stops9h 25m
Southwest
Sun 5/313:05 pm
ECP
- CHS
1 stop5h 25m
Southwest
Deal found 4/5![Southwest logo]()
$400
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/412:00 pm
CHS
- ECP
2 stops10h 40m
Southwest
Sun 6/712:10 pm
ECP
- CHS
2 stops8h 35m
Southwest
Deal found 4/9![Southwest logo]()
$402
Best flights from Charleston to Panama CityDiscover carefully curated flight deals from Charleston to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 10, 2026.
Discover carefully curated flight deals from Charleston to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 10, 2026.
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/211:15 am
CHS
- ECP
2 stops10h 10m
Southwest
Sat 5/97:20 am
ECP
- CHS
1 stop3h 40m
Southwest
Deal found 4/7![Southwest logo]()
$316
This Delta deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/125:10 am
CHS
- ECP
1 stop4h 10m
Delta
Fri 7/176:41 pm
ECP
- CHS
1 stop3h 38m
Delta
Deal found 4/8![Delta logo]()
$395
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:40 am
CHS
- ECP
1 stop3h 50m
Southwest
Tue 5/127:55 am
ECP
- CHS
2 stops11h 05m
Southwest
Deal found 4/7![Southwest logo]()
$316
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/412:00 pm
CHS
- ECP
2 stops10h 40m
Southwest
Sun 6/77:20 am
ECP
- CHS
1 stop6h 25m
Southwest
Deal found 4/9![Southwest logo]()
$358
This Delta deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/116:00 am
CHS
- ECP
1 stop3h 20m
Delta
Fri 7/179:15 am
ECP
- CHS
1 stop5h 38m
Delta
Deal found 4/9![Delta logo]()
$395
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/281:15 pm
CHS
- ECP
2 stops9h 25m
Southwest
Sun 5/313:05 pm
ECP
- CHS
1 stop5h 25m
Southwest
Deal found 4/5![Southwest logo]()
$400
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/231:17 pm
CHS
- ECP
1 stop6h 19m
Delta
Mon 5/254:54 pm
ECP
- CHS
1 stop3h 58m
Delta
Deal found 4/5![Delta logo]()
$449
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1112:00 pm
CHS
- ECP
2 stops10h 55m
Southwest
Fri 7/176:55 am
ECP
- CHS
2 stops8h 10m
Southwest
Deal found 4/5![Southwest logo]()
$405
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/81:15 pm
CHS
- ECP
2 stops9h 25m
Southwest
Tue 5/127:15 am
ECP
- CHS
2 stops10h 20m
Southwest
Deal found 4/8![Southwest logo]()
$424
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2312:40 pm
CHS
- ECP
2 stops7h 20m
Southwest
Mon 5/256:40 am
ECP
- CHS
2 stops10h 40m
Southwest
Deal found 4/5![Southwest logo]()
$494
Last-minute flights from Charleston to Panama CityDiscover last-minute flight deals from Charleston to Panama City. Data last updated April 10, 2026 and is based on user searches.
Discover last-minute flight deals from Charleston to Panama City. Data last updated April 10, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/211:15 am
CHS
- ECP
1 stop7h 35m
Southwest
Sat 5/97:20 am
ECP
- CHS
1 stop3h 40m
Southwest
Deal found 4/7![Southwest logo]()
$311
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/211:15 am
CHS
- ECP
1 stop7h 35m
Southwest
Fri 5/89:55 am
ECP
- CHS
2 stops10h 35m
Southwest
Deal found 4/8![Southwest logo]()
$358
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/512:00 pm
CHS
- ECP
2 stops9h 45m
Southwest
Tue 5/127:15 am
ECP
- CHS
2 stops10h 20m
Southwest
Deal found 4/7![Southwest logo]()
$321
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/82:15 pm
CHS
- ECP
1 stop5h 05m
Southwest
Tue 5/1212:05 pm
ECP
- CHS
1 stop6h 55m
Southwest
Deal found 4/8![Southwest logo]()
$353
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/82:15 pm
CHS
- ECP
1 stop5h 05m
Southwest
Mon 5/116:40 am
ECP
- CHS
2 stops8h 30m
Southwest
Deal found 4/8![Southwest logo]()
$400
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/82:15 pm
CHS
- ECP
1 stop5h 05m
Southwest
Sun 5/105:35 am
ECP
- CHS
1 stop10h 55m
Southwest
Deal found 4/9![Southwest logo]()
$436
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/283:20 pm
CHS
- ECP
1 stop4h 06m
American Airlines
Sun 5/316:45 pm
ECP
- CHS
1 stop4h 14m
American Airlines
Deal found 4/5![American Airlines logo]()
$373
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/281:15 pm
CHS
- ECP
2 stops9h 25m
Southwest
Sun 5/315:35 am
ECP
- CHS
2 stops8h 25m
Southwest
Deal found 4/5![Southwest logo]()
$433
One-way flights from Charleston to Panama CitySearch for one-way flight options from Charleston to Panama City. Find affordable one-way fares based on user searches. Data last updated April 10, 2026.
Search for one-way flight options from Charleston to Panama City. Find affordable one-way fares based on user searches. Data last updated April 10, 2026.
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:20 pm
CHS
- ECP
1 stop6h 26m
American Airlines
Deal found 4/8![American Airlines logo]()
$156
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:40 am
CHS
- ECP
2 stops10h 40m
Southwest
Deal found 4/8![Southwest logo]()
$167
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/17:44 pm
CHS
- ECP
1 stop4h 28m
Delta
Deal found 4/6![Delta logo]()
$234
This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/227:50 pm
CHS
- ECP
1 stop4h 50m
American Airlines
Deal found 4/10![American Airlines logo]()
$244
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/110:55 am
CHS
- ECP
2 stops11h 45m
Southwest
Deal found 4/6![Southwest logo]()
$264
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/308:05 am
CHS
- ECP
2 stops12h 45m
Southwest
Deal found 4/6![Southwest logo]()
$279
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:35 am
CHS
- ECP
3 stops31h 43m
United Airlines
Deal found 4/6![United Airlines logo]()
$561
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:35 am
CHS
- ECP
3 stops31h 43m
United Airlines
Deal found 4/6![United Airlines logo]()
$603
Find flight deals from Charleston to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $311 (Southwest) |
One-way from | $156 (American Airlines) |
Popular in | April |
Cheapest in | August |
Average price | $707 |
Cheapflights Fare Finder
Customize your flight search to find flights from Charleston to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 10, 2026.
Use the filters below to find and compare flights from Charleston to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonPanama City
CHS - ECP
CHSECP
Charleston
Sat 5/2
11:15 am-8:25 pm
2 stops10h 10m
Panama City NW Florida Beaches
Sat 5/9
7:20 am-12:00 pm
1 stop3h 40m
$316
CharlestonPanama City
CHS - ECP
CHSECP
Charleston
Tue 5/5
6:40 am-9:30 am
1 stop3h 50m
Panama City NW Florida Beaches
Tue 5/12
7:55 am-8:00 pm
2 stops11h 05m
$316
CharlestonPanama City
CHS - ECP
CHSECP
Charleston
Thu 6/4
12:00 pm-9:40 pm
2 stops10h 40m
Panama City NW Florida Beaches
Sun 6/7
7:20 am-2:45 pm
1 stop6h 25m
$358
Quickest round-trip
CharlestonPanama City
CHS - ECP
CHSECP
Charleston
Sun 7/12
5:10 am-8:20 am
1 stop4h 10m
Panama City NW Florida Beaches
Fri 7/17
6:41 pm-11:19 pm
1 stop3h 38m
$395
CharlestonPanama City
CHS - ECP
CHSECP
Charleston
Sat 7/11
6:00 am-8:20 am
1 stop3h 20m
Panama City NW Florida Beaches
Fri 7/17
9:15 am-3:53 pm
1 stop5h 38m
$395
CharlestonPanama City
CHS - ECP
CHSECP
Charleston
Thu 5/28
1:15 pm-9:40 pm
2 stops9h 25m
Panama City NW Florida Beaches
Sun 5/31
3:05 pm-9:30 pm
1 stop5h 25m
$400
CharlestonPanama City
CHS - ECP
CHSECP
Charleston
Sat 7/11
12:00 pm-9:55 pm
2 stops10h 55m
Panama City NW Florida Beaches
Fri 7/17
6:55 am-4:05 pm
2 stops8h 10m
$405
CharlestonPanama City
CHS - ECP
CHSECP
Charleston
Fri 5/8
1:15 pm-9:40 pm
2 stops9h 25m
Panama City NW Florida Beaches
Tue 5/12
7:15 am-6:35 pm
2 stops10h 20m
$424
CharlestonPanama City
CHS - ECP
CHSECP
Charleston
Sat 5/23
1:17 pm-6:36 pm
1 stop6h 19m
Panama City NW Florida Beaches
Mon 5/25
4:54 pm-9:52 pm
1 stop3h 58m
$449
CharlestonPanama City
CHS - ECP
CHSECP
Charleston
Sat 5/23
12:40 pm-7:00 pm
2 stops7h 20m
Panama City NW Florida Beaches
Mon 5/25
6:40 am-6:20 pm
2 stops10h 40m
$494
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Charleston to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charleston to Panama City in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Charleston-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Charleston-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Charleston-Panama City, Florida flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Charleston-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Charleston to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Charleston with our price prediction graph.
CHS-ECP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Charleston to Panama City
What is the cheapest month to book a flight from Charleston to Panama City, Florida?
Currently, September is the cheapest month in which you can book a flight from Charleston to Panama City, Florida (average of $138). Flying from Charleston to Panama City, Florida in March is currently the most expensive (average of $313). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Charleston to Panama City, Florida?
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated April 10, 2026.
Read reviews from past customers who have flown Delta and American Airlines from Charleston to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Overall
7.9
Boarding
8.1
Comfort
7.9
Entertainment
7.8
Food
7.2
Reviews
1 / 20
8.0
ExcellentMatthew,Oct 2025
GSP - ATL
Crew
8.5
Overall
7.9
Boarding
8.1
Comfort
7.9
Entertainment
7.8
Food
7.2
Reviews
1 / 20
8.0
ExcellentMatthew,Oct 2025
GSP - ATL
Crew
8.5
Overall
7.9
Boarding
8.1
Comfort
7.9
Entertainment
7.8
Food
7.2
Reviews
1 / 20
8.0
ExcellentMatthew,Oct 2025
GSP - ATL
Related info for your journey
Find useful and relevant information for your journey from Charleston to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Panama City?
Book flights to Panama City if you plan to visit one of these locationsMexico Beach
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Charleston and Panama City flights
Browse other Charleston and Panama City flight options. Last updated on April 10, 2026.
Other flights from Charleston
Browse through other flights departing from Charleston. Flights are based on user searches made on Cheapflights and were last updated on April 10, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Charleston to Panama City
Discover the top 2 airlines that operate flights from Charleston to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$231 | Average$387 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$272 | Average$368 | FlexibilityNo cancel fee | On-time71% |