$177+ Cheap flights from Charleston to Panama City, FL (CHS - ECP)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/16. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — ECP
Mar 25 — Apr 11
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Charleston to Panama City
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Best
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Cheapest flights from Charleston to Panama CityExplore the most affordable flight options available from Charleston to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 23, 2026.
Explore the most affordable flight options available from Charleston to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 23, 2026.
This American Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/148:21 pm
CHS
- ECP
1 stop4h 25m
American Airlines
Tue 5/194:40 pm
ECP
- CHS
1 stop4h 06m
American Airlines
Deal found 2/21![American Airlines logo]()
$334
This Delta deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/131:17 pm
CHS
- ECP
1 stop4h 13m
Delta
Sun 5/176:00 am
ECP
- CHS
1 stop5h 10m
Delta
Deal found 2/22![Delta logo]()
$335
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:35 am
CHS
- ECP
1 stop3h 50m
Southwest
Tue 9/17:45 am
ECP
- CHS
2 stops10h 30m
Southwest
Deal found 2/19![Southwest logo]()
$340
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:00 am
CHS
- ECP
1 stop6h 03m
American Airlines
Tue 4/284:40 pm
ECP
- CHS
1 stop4h 06m
American Airlines
Deal found 2/19![American Airlines logo]()
$351
This American Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/148:21 pm
CHS
- ECP
1 stop4h 25m
American Airlines
Mon 5/1810:48 am
ECP
- CHS
1 stop4h 18m
American Airlines
Deal found 2/21![American Airlines logo]()
$353
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1210:30 am
CHS
- ECP
1 stop3h 08m
Delta
Mon 6/1511:15 am
ECP
- CHS
1 stop3h 24m
Delta
Deal found 2/20![Delta logo]()
$355
This Southwest deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/217:55 am
CHS
- ECP
2 stops10h 40m
Southwest
Sat 3/282:50 pm
ECP
- CHS
1 stop5h 50m
Southwest
Deal found 2/21![Southwest logo]()
$364
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/113:15 pm
CHS
- ECP
1 stop7h 25m
Southwest
Sun 6/144:20 pm
ECP
- CHS
1 stop5h 30m
Southwest
Deal found 2/20![Southwest logo]()
$381
This Southwest deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/103:15 pm
CHS
- ECP
1 stop7h 25m
Southwest
Fri 7/177:50 am
ECP
- CHS
1 stop3h 50m
Southwest
Deal found 2/22![Southwest logo]()
$391
Best flights from Charleston to Panama CityDiscover carefully curated flight deals from Charleston to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 23, 2026.
Discover carefully curated flight deals from Charleston to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 23, 2026.
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:00 am
CHS
- ECP
1 stop6h 03m
American Airlines
Tue 4/284:40 pm
ECP
- CHS
1 stop4h 06m
American Airlines
Deal found 2/19![American Airlines logo]()
$351
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1210:30 am
CHS
- ECP
1 stop3h 08m
Delta
Mon 6/1511:15 am
ECP
- CHS
1 stop3h 24m
Delta
Deal found 2/20![Delta logo]()
$355
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/113:15 pm
CHS
- ECP
1 stop7h 25m
Southwest
Sun 6/145:40 am
ECP
- CHS
2 stops9h 40m
Southwest
Deal found 2/20![Southwest logo]()
$386
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/167:30 am
CHS
- ECP
1 stop6h 08m
Delta
Mon 7/207:05 pm
ECP
- CHS
1 stop3h 52m
Delta
Deal found 2/20![Delta logo]()
$355
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:59 pm
CHS
- ECP
1 stop4h 29m
Delta
Sun 5/176:00 am
ECP
- CHS
1 stop5h 10m
Delta
Deal found 2/19![Delta logo]()
$355
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/226:25 am
CHS
- ECP
1 stop4h 10m
Southwest
Sun 6/285:40 am
ECP
- CHS
2 stops9h 40m
Southwest
Deal found 2/19![Southwest logo]()
$396
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/135:30 am
CHS
- ECP
1 stop3h 47m
Delta
Fri 7/171:30 pm
ECP
- CHS
1 stop6h 11m
Delta
Deal found 2/19![Delta logo]()
$355
This Delta deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:30 am
CHS
- ECP
1 stop4h 44m
Delta
Sun 6/286:00 am
ECP
- CHS
1 stop4h 24m
Delta
Deal found 2/22![Delta logo]()
$395
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/307:44 pm
CHS
- ECP
1 stop4h 28m
Delta
Sun 5/35:49 am
ECP
- CHS
1 stop3h 06m
Delta
Deal found 2/19![Delta logo]()
$395
Last-minute flights from Charleston to Panama CityDiscover last-minute flight deals from Charleston to Panama City. Data last updated February 23, 2026 and is based on user searches.
Discover last-minute flight deals from Charleston to Panama City. Data last updated February 23, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/610:35 am
CHS
- ECP
2 stops11h 45m
Southwest
Mon 3/97:20 am
ECP
- CHS
1 stop3h 45m
Southwest
Deal found 2/20![Southwest logo]()
$502
This American Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/66:35 am
CHS
- ECP
1 stop4h 31m
American Airlines
Mon 3/97:19 am
ECP
- CHS
1 stop5h 34m
American Airlines
Deal found 2/22![American Airlines logo]()
$567
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/78:17 pm
CHS
- ECP
1 stop4h 32m
American Airlines
Mon 3/94:34 pm
ECP
- CHS
1 stop5h 27m
American Airlines
Deal found 2/20![American Airlines logo]()
$497
This Southwest deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/97:40 am
CHS
- ECP
2 stops10h 40m
Southwest
Fri 3/131:25 pm
ECP
- CHS
1 stop7h 15m
Southwest
Deal found 2/22![Southwest logo]()
$508
This Southwest deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/215:30 am
CHS
- ECP
1 stop7h 15m
Southwest
Sat 3/282:50 pm
ECP
- CHS
1 stop5h 50m
Southwest
Deal found 2/21![Southwest logo]()
$353
This Southwest deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/226:15 am
CHS
- ECP
1 stop4h 00m
Southwest
Sun 3/295:25 am
ECP
- CHS
2 stops12h 20m
Southwest
Deal found 2/22![Southwest logo]()
$492
This Delta deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/226:30 am
CHS
- ECP
1 stop3h 10m
Delta
Sun 3/296:43 pm
ECP
- CHS
1 stop4h 33m
Delta
Deal found 2/22![Delta logo]()
$539
One-way flights from Charleston to Panama CitySearch for one-way flight options from Charleston to Panama City. Find affordable one-way fares based on user searches. Data last updated February 23, 2026.
Search for one-way flight options from Charleston to Panama City. Find affordable one-way fares based on user searches. Data last updated February 23, 2026.
This American Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/166:45 pm
CHS
- ECP
1 stop6h 04m
American Airlines
Deal found 2/22![American Airlines logo]()
$177
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/67:58 pm
CHS
- ECP
1 stop4h 06m
Delta
Deal found 2/19![Delta logo]()
$178
This Southwest deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/1610:35 am
CHS
- ECP
2 stops11h 45m
Southwest
Deal found 2/22![Southwest logo]()
$213
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/56:45 pm
CHS
- ECP
1 stop6h 04m
American Airlines
Deal found 2/19![American Airlines logo]()
$214
This American Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/228:19 pm
CHS
- ECP
1 stop4h 30m
American Airlines
Deal found 2/22![American Airlines logo]()
$218
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/56:15 am
CHS
- ECP
2 stops9h 00m
Southwest
Deal found 2/19![Southwest logo]()
$219
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:05 am
CHS
- ECP
2 stops11h 10m
Southwest
Deal found 2/19![Southwest logo]()
$227
This Southwest deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/226:15 am
CHS
- ECP
2 stops9h 00m
Southwest
Deal found 2/22![Southwest logo]()
$470
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/166:32 pm
CHS
- ECP
3 stops46h 04m
Multiple Airlines
Deal found 2/22![Multiple Airlines logo]()
$644
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:53 pm
CHS
- ECP
3 stops29h 11m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$664
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/56:53 pm
CHS
- ECP
3 stops40h 30m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$720
Find flight deals from Charleston to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $334 (American Airlines) |
One-way from | $177 (American Airlines) |
Popular in | December |
Cheapest in | March |
Average price | $368 |
Cheapflights Fare Finder
Customize your flight search to find flights from Charleston to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 23, 2026.
Use the filters below to find and compare flights from Charleston to Panama City that are best for you.
Fly from
Charleston
Fly to
Panama City
Route
Depart
Return
Price
CharlestonPanama City
CHS - ECP
CHSECP
Charleston
Wed 4/22
5:00 am-10:03 am
1 stop6h 03m
Panama City NW Florida Beaches
Tue 4/28
4:40 pm-9:46 pm
1 stop4h 06m
$351
CharlestonPanama City
CHS - ECP
CHSECP
Charleston
Fri 6/12
10:30 am-12:38 pm
1 stop3h 08m
Panama City NW Florida Beaches
Mon 6/15
11:15 am-3:39 pm
1 stop3h 24m
$355
CharlestonPanama City
CHS - ECP
CHSECP
Charleston
Thu 7/16
7:30 am-12:38 pm
1 stop6h 08m
Panama City NW Florida Beaches
Mon 7/20
7:05 pm-11:57 pm
1 stop3h 52m
$355
CharlestonPanama City
CHS - ECP
CHSECP
Charleston
Fri 5/15
7:59 pm-11:28 pm
1 stop4h 29m
Panama City NW Florida Beaches
Sun 5/17
6:00 am-12:10 pm
1 stop5h 10m
$355
CharlestonPanama City
CHS - ECP
CHSECP
Charleston
Mon 7/13
5:30 am-8:17 am
1 stop3h 47m
Panama City NW Florida Beaches
Fri 7/17
1:30 pm-8:41 pm
1 stop6h 11m
$355
CharlestonPanama City
CHS - ECP
CHSECP
Charleston
Thu 6/11
3:15 pm-9:40 pm
1 stop7h 25m
Panama City NW Florida Beaches
Sun 6/14
5:40 am-4:20 pm
2 stops9h 40m
$386
CharlestonPanama City
CHS - ECP
CHSECP
Charleston
Thu 6/25
6:30 am-10:14 am
1 stop4h 44m
Panama City NW Florida Beaches
Sun 6/28
6:00 am-11:24 am
1 stop4h 24m
$395
CharlestonPanama City
CHS - ECP
CHSECP
Charleston
Thu 4/30
7:44 pm-11:12 pm
1 stop4h 28m
Panama City NW Florida Beaches
Sun 5/3
5:49 am-9:55 am
1 stop3h 06m
$395
CharlestonPanama City
CHS - ECP
CHSECP
Charleston
Mon 6/22
6:25 am-9:35 am
1 stop4h 10m
Panama City NW Florida Beaches
Sun 6/28
5:40 am-4:20 pm
2 stops9h 40m
$396
CharlestonPanama City
CHS - ECP
CHSECP
Charleston
Mon 4/6
7:58 pm-11:04 pm
1 stop4h 06m
$178
Showing 1-10 of 17 results
Compare providers for flights from Charleston to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charleston to Panama City in February.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Charleston-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Charleston-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Charleston-Panama City, Florida flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Charleston-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Charleston to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Charleston with our price prediction graph.
CHS-ECP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Charleston to Panama City
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated February 23, 2026.
Read reviews from past customers who have flown Southwest, Delta, and American Airlines from Charleston to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Crew
8.6
Boarding
8.1
Overall
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Crew
8.6
Boarding
8.1
Overall
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Crew
8.6
Boarding
8.1
Overall
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Crew
8.6
Boarding
8.1
Overall
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Charleston to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Panama City?
Book flights to Panama City if you plan to visit one of these locationsMexico Beach
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Charleston and Panama City flights
Browse other Charleston and Panama City flight options. Last updated on February 23, 2026.
Other flights from Charleston
Browse through other flights departing from Charleston. Flights are based on user searches made on Cheapflights and were last updated on February 23, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on February 23, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Charleston to Panama City
Discover the top 3 airlines that operate flights from Charleston to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$216 | Average$321 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$231 | Average$387 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$283 | Average$447 | FlexibilityNo cancel fee | On-time63% |