$267+ Cheap flights from Panama City, FL to Charleston (ECP - CHS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/19. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — CHS
Oct 19 — Oct 261
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to Charleston with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to Charleston
Cheapest
Best
Last-minute
Cheapest flights from Panama City to CharlestonExplore the most affordable flight options available from Panama City to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 19, 2026.
Explore the most affordable flight options available from Panama City to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 19, 2026.
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:00 am -
1 stop3h 10m
Wed 10/215:30 am -
1 stop6h 05m
Deal found 9/14![Delta logo]()
$267
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/154:30 pm -
1 stop5h 21m
Mon 10/195:30 am -
1 stop3h 44m
Deal found 9/14![Delta logo]()
$283
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:01 pm -
1 stop3h 56m
Tue 11/1012:03 pm -
1 stop6h 06m
Deal found 9/14![American Airlines logo]()
$284
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/63:00 pm -
1 stop8h 35m
Tue 11/106:35 am -
2 stops10h 00m
Deal found 9/14![Southwest logo]()
$295
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:00 am -
1 stop3h 10m
Mon 10/125:30 am -
1 stop3h 44m
Deal found 9/15![Delta logo]()
$347
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:15 am -
1 stop4h 35m
Wed 10/216:40 am -
2 stops10h 50m
Deal found 9/14![Southwest logo]()
$443
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/153:10 pm -
1 stop8h 10m
Mon 10/196:35 am -
2 stops8h 55m
Deal found 9/14![Southwest logo]()
$491
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/42:40 pm -
1 stop6h 25m
Tue 10/67:15 am -
2 stops9h 15m
Deal found 9/14![Southwest logo]()
$540
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/87:15 am -
2 stops10h 43m
Mon 10/128:08 pm -
1 stop4h 45m
Deal found 9/15![American Airlines logo]()
$614
Best flights from Panama City to CharlestonDiscover carefully curated flight deals from Panama City to Charleston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 19, 2026.
Discover carefully curated flight deals from Panama City to Charleston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 19, 2026.
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/63:00 pm -
1 stop8h 35m
Tue 11/106:35 am -
2 stops10h 00m
Deal found 9/14![Southwest logo]()
$295
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:00 am -
1 stop3h 10m
Mon 10/125:30 am -
1 stop3h 44m
Deal found 9/15![Delta logo]()
$347
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/62:08 pm -
1 stop22h 43m
Sat 1/94:45 pm -
1 stop21h 32m
Deal found 9/15![United Airlines logo]()
$719
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/153:10 pm -
1 stop8h 10m
Mon 10/196:35 am -
2 stops8h 55m
Deal found 9/14![Southwest logo]()
$491
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/42:40 pm -
1 stop6h 25m
Tue 10/67:15 am -
2 stops9h 15m
Deal found 9/14![Southwest logo]()
$540
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:15 am -
2 stops11h 10m
Wed 10/216:40 am -
2 stops10h 50m
Deal found 9/14![Southwest logo]()
$578
Last-minute flights from Panama City to CharlestonDiscover last-minute flight deals from Panama City to Charleston. Data last updated September 19, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Charleston. Data last updated September 19, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1811:19 am -
1 stop4h 11m
Wed 9/235:25 am -
1 stop3h 51m
Deal found 9/16![Delta logo]()
$636
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/211:30 pm -
1 stop4h 45m
Wed 9/238:10 am -
2 stops11h 40m
Deal found 9/17![Southwest logo]()
$641
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/42:40 pm -
1 stop6h 25m
Tue 10/67:15 am -
2 stops9h 15m
Deal found 9/14![Southwest logo]()
$540
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:00 am -
1 stop3h 10m
Mon 10/125:30 am -
1 stop3h 44m
Deal found 9/15![Delta logo]()
$347
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/87:15 am -
2 stops10h 43m
Mon 10/128:08 pm -
1 stop4h 45m
Deal found 9/15![American Airlines logo]()
$614
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/154:30 pm -
1 stop5h 21m
Mon 10/195:30 am -
1 stop3h 44m
Deal found 9/14![Delta logo]()
$283
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/153:10 pm -
1 stop8h 10m
Mon 10/196:35 am -
2 stops8h 55m
Deal found 9/14![Southwest logo]()
$491
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:00 am -
1 stop3h 10m
Wed 10/215:30 am -
1 stop6h 05m
Deal found 9/14![Delta logo]()
$267
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:15 am -
1 stop4h 35m
Wed 10/216:40 am -
2 stops10h 50m
Deal found 9/14![Southwest logo]()
$443
Find flight deals from Panama City to Charleston
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Charleston (CHS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 19, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $267 (Delta) |
Popular in | February |
Cheapest in | December |
Average price | $658 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 19, 2026.
Use the filters below to find and compare flights from Panama City to Charleston that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityCharleston
ECP Panama City NW Florida Beaches - CHS Charleston
ECPCHS
Panama City NW Florida Beaches
Fri 11/6
3:00 pm-12:35 am
1 stop8h 35m
Charleston
Tue 11/10
6:35 am-3:35 pm
2 stops10h 00m
$295
Quickest round-trip
Panama CityCharleston
ECP Panama City NW Florida Beaches - CHS Charleston
ECPCHS
Panama City NW Florida Beaches
Thu 10/8
6:00 am-10:10 am
1 stop3h 10m
Charleston
Mon 10/12
5:30 am-8:14 am
1 stop3h 44m
$347
Panama CityCharleston
ECP Panama City NW Florida Beaches - CHS Charleston
ECPCHS
Panama City NW Florida Beaches
Thu 10/15
3:10 pm-12:20 am
1 stop8h 10m
Charleston
Mon 10/19
6:35 am-2:30 pm
2 stops8h 55m
$491
Panama CityCharleston
ECP Panama City NW Florida Beaches - CHS Charleston
ECPCHS
Panama City NW Florida Beaches
Sun 10/4
2:40 pm-10:05 pm
1 stop6h 25m
Charleston
Tue 10/6
7:15 am-3:30 pm
2 stops9h 15m
$540
Panama CityCharleston
ECP Panama City NW Florida Beaches - CHS Charleston
ECPCHS
Panama City NW Florida Beaches
Mon 10/19
7:15 am-7:25 pm
2 stops11h 10m
Charleston
Wed 10/21
6:40 am-4:30 pm
2 stops10h 50m
$578
Panama CityCharleston
ECP Panama City NW Florida Beaches - CHS Charleston
ECPCHS
Panama City NW Florida Beaches
Wed 1/6
2:08 pm-1:51 pm
1 stop22h 43m
Charleston
Sat 1/9
4:45 pm-1:17 pm
1 stop21h 32m
$719
Sorted by cheapest first
Compare providers for flights from Panama City to Charleston
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Charleston in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Panama City, Florida-Charleston flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-Charleston flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Charleston flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City, Florida-Charleston flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Charleston flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to Charleston
Have a flexible travel schedule? Discover the best time to fly to Charleston from Panama City with our price prediction graph.
ECP-CHS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Charleston
Reviews of airlines servicing Charleston
Get insights into the airlines that provide service to Charleston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charleston. Reviews last updated September 19, 2026.
See what other customers who have flown with Delta from Panama City to Charleston have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Comfort
7.8
Crew
8.5
Boarding
8.1
Overall
7.8
Entertainment
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Food
7.2
Comfort
7.8
Crew
8.5
Boarding
8.1
Overall
7.8
Entertainment
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from Panama City to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Charleston?
Book flights to Charleston if you plan to visit one of these locationsNorth Charleston
Santee
Summerville
Walterboro
Mount Pleasant
Goose Creek
Edisto Beach
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
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Complete your trip
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Alternative routes for Panama City to Charleston
See prices for flight routes from nearby airports that may be better suited for you.
Other flights to Charleston
Explore flights to Charleston departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 19, 2026.
Complete your trip
Complete your trip to Charleston by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Panama City to Charleston by cabin class
Find flights from Panama City to Charleston, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Panama City and Charleston flights
Browse other Panama City and Charleston flight options. Last updated on September 19, 2026.
Other flights from Panama City
Browse through other flights departing from Panama City. Flights are based on user searches made on Cheapflights and were last updated on September 19, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Panama City to Charleston
Discover the top airline that operate flights from Panama City to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$296 | Average$394 | FlexibilityNo cancel fee | On-timeN/A |