$285+ Cheap flights from Panama to North Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/17. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — RDU
Mar 14 — Mar 211
1 adult, Economy
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Find cheap flights from Panama to North Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama to North Carolina
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Cheapest flights from Panama to North CarolinaExplore the most affordable flight options available from Panama to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 12, 2026.
Explore the most affordable flight options available from Panama to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 12, 2026.
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/103:40 pm
PTY
- CLT
1 stop15h 42m
American Airlines
Mon 9/149:00 pm
CLT
- PTY
1 stop18h 10m
American Airlines
Deal found 2/9![American Airlines logo]()
$428
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/11:49 pm
PTY
- CLT
1 stop19h 11m
American Airlines
Fri 5/155:05 am
CLT
- PTY
1 stop8h 41m
American Airlines
Deal found 2/11![American Airlines logo]()
$459
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/239:33 pm
PTY
- RDU
1 stop9h 00m
Multiple Airlines
Tue 5/54:07 pm
RDU
- PTY
2 stops16h 59m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$477
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/192:28 pm
PTY
- GSO
1 stop8h 31m
Delta
Tue 3/315:19 am
GSO
- PTY
1 stop8h 44m
Delta
Deal found 2/11![Delta logo]()
$501
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/301:49 pm
PTY
- CLT
1 stop8h 08m
American Airlines
Thu 5/148:45 pm
CLT
- PTY
1 stop17h 01m
American Airlines
Deal found 2/9![American Airlines logo]()
$502
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/261:40 pm
PTY
- AVL
2 stops17h 42m
American Airlines
Tue 3/314:13 pm
AVL
- PTY
2 stops21h 27m
American Airlines
Deal found 2/9![American Airlines logo]()
$504
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/302:27 pm
PTY
- RDU
1 stop8h 51m
Delta
Sat 5/25:18 am
RDU
- PTY
1 stop8h 44m
Delta
Deal found 2/9![Delta logo]()
$504
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/192:28 pm
PTY
- GSO
1 stop8h 31m
Delta
Mon 3/306:35 am
GSO
- PTY
1 stop7h 28m
Delta
Deal found 2/11![Delta logo]()
$510
This Copa Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:57 am
PTY
- RDU
Nonstop4h 32m
Copa Airlines
Sun 5/104:19 pm
RDU
- PTY
Nonstop4h 27m
Copa Airlines
Deal found 2/8![Copa Airlines logo]()
$514
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/191:40 pm
PTY
- GSO
2 stops20h 00m
American Airlines
Tue 4/77:20 pm
GSO
- PTY
2 stops18h 26m
American Airlines
Deal found 2/11![American Airlines logo]()
$515
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/301:49 pm
PTY
- RDU
2 stops19h 24m
American Airlines
Sat 5/27:43 pm
RDU
- PTY
2 stops18h 03m
American Airlines
Deal found 2/9![American Airlines logo]()
$517
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/207:55 am
PTY
- RDU
1 stop13h 03m
United Airlines
Sat 5/236:27 pm
RDU
- PTY
1 stop10h 37m
United Airlines
Deal found 2/8![United Airlines logo]()
$523
Best flights from Panama to North CarolinaDiscover carefully curated flight deals from Panama to North Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 12, 2026.
Discover carefully curated flight deals from Panama to North Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 12, 2026.
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/11:49 pm
PTY
- CLT
1 stop19h 11m
American Airlines
Fri 5/155:05 am
CLT
- PTY
1 stop8h 41m
American Airlines
Deal found 2/9![American Airlines logo]()
$467
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/239:33 pm
PTY
- RDU
1 stop9h 00m
Multiple Airlines
Tue 5/54:07 pm
RDU
- PTY
2 stops16h 59m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$477
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/192:28 pm
PTY
- GSO
1 stop8h 31m
Delta
Tue 3/315:19 am
GSO
- PTY
1 stop8h 44m
Delta
Deal found 2/11![Delta logo]()
$501
This Copa Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:57 am
PTY
- RDU
Nonstop4h 32m
Copa Airlines
Sun 5/104:19 pm
RDU
- PTY
Nonstop4h 27m
Copa Airlines
Deal found 2/8![Copa Airlines logo]()
$514
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/207:55 am
PTY
- RDU
1 stop13h 03m
United Airlines
Sat 5/236:27 pm
RDU
- PTY
1 stop10h 37m
United Airlines
Deal found 2/8![United Airlines logo]()
$523
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/301:49 pm
PTY
- CLT
1 stop8h 08m
American Airlines
Thu 5/148:45 pm
CLT
- PTY
1 stop17h 01m
American Airlines
Deal found 2/9![American Airlines logo]()
$502
This Delta deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/302:27 pm
PTY
- RDU
1 stop8h 51m
Delta
Sat 5/27:25 am
RDU
- PTY
1 stop6h 37m
Delta
Deal found 2/8![Delta logo]()
$504
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/239:33 pm
PTY
- CLT
1 stop14h 47m
Multiple Airlines
Wed 3/47:00 am
CLT
- PTY
1 stop9h 06m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$510
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/261:40 pm
PTY
- AVL
2 stops17h 42m
American Airlines
Tue 3/314:13 pm
AVL
- PTY
2 stops21h 27m
American Airlines
Deal found 2/9![American Airlines logo]()
$504
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/192:28 pm
PTY
- GSO
1 stop8h 31m
Delta
Mon 3/306:35 am
GSO
- PTY
1 stop7h 28m
Delta
Deal found 2/11![Delta logo]()
$510
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/712:03 pm
PTY
- CLT
1 stop11h 53m
Multiple Airlines
Sat 3/148:56 am
CLT
- PTY
1 stop12h 23m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$521
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/259:45 am
PTY
- GSO
1 stop11h 12m
United Airlines
Tue 4/2812:09 pm
GSO
- PTY
1 stop8h 22m
United Airlines
Deal found 2/11![United Airlines logo]()
$594
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/191:40 pm
PTY
- GSO
2 stops20h 00m
American Airlines
Tue 4/77:20 pm
GSO
- PTY
2 stops18h 26m
American Airlines
Deal found 2/11![American Airlines logo]()
$515
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/192:28 pm
PTY
- GSO
1 stop8h 31m
Delta
Sun 3/297:57 pm
GSO
- PTY
1 stop18h 06m
Delta
Deal found 2/11![Delta logo]()
$524
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/41:49 pm
PTY
- RDU
2 stops20h 22m
American Airlines
Sun 5/106:28 pm
RDU
- PTY
2 stops19h 18m
American Airlines
Deal found 2/8![American Airlines logo]()
$517
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/301:49 pm
PTY
- RDU
2 stops20h 22m
American Airlines
Sat 5/26:28 pm
RDU
- PTY
2 stops19h 18m
American Airlines
Deal found 2/8![American Airlines logo]()
$517
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/192:28 pm
PTY
- GSO
1 stop8h 31m
Delta
Wed 4/15:19 am
GSO
- PTY
1 stop8h 44m
Delta
Deal found 2/11![Delta logo]()
$575
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/192:28 pm
PTY
- GSO
1 stop8h 31m
Delta
Wed 4/86:35 am
GSO
- PTY
1 stop7h 28m
Delta
Deal found 2/11![Delta logo]()
$575
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/81:49 pm
PTY
- CLT
1 stop19h 11m
American Airlines
Sun 4/128:45 pm
CLT
- PTY
1 stop17h 01m
American Airlines
Deal found 2/11![American Airlines logo]()
$527
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/192:28 pm
PTY
- GSO
1 stop8h 31m
Delta
Thu 4/96:35 am
GSO
- PTY
1 stop7h 28m
Delta
Deal found 2/11![Delta logo]()
$575
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/193:10 pm
PTY
- GSO
2 stops18h 30m
American Airlines
Tue 3/317:01 am
GSO
- PTY
1 stop6h 39m
American Airlines
Deal found 2/11![American Airlines logo]()
$537
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/192:28 pm
PTY
- GSO
1 stop8h 31m
Delta
Sat 3/285:46 pm
GSO
- PTY
1 stop20h 17m
Delta
Deal found 2/11![Delta logo]()
$617
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/2611:33 am
PTY
- AVL
2 stops33h 23m
Multiple Airlines
Tue 3/314:18 pm
AVL
- PTY
1 stop29h 01m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$948
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/251:49 pm
PTY
- GSO
2 stops20h 20m
American Airlines
Tue 4/287:20 pm
GSO
- PTY
2 stops18h 26m
American Airlines
Deal found 2/11![American Airlines logo]()
$590
This WestJet deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure WestJet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/2410:20 am
PTY
- MYR
2 stops37h 37m
WestJet
Thu 2/2610:31 am
MYR
- PTY
2 stops46h 49m
WestJet
Deal found 2/9![WestJet logo]()
$2,391
Last-minute flights from Panama to North CarolinaDiscover last-minute flight deals from Panama to North Carolina. Data last updated February 12, 2026 and is based on user searches.
Discover last-minute flight deals from Panama to North Carolina. Data last updated February 12, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/154:05 pm
PTY
- CLT
1 stop8h 19m
American Airlines
Wed 2/256:40 pm
CLT
- PTY
1 stop20h 35m
American Airlines
Deal found 2/11![American Airlines logo]()
$572
This Avianca Connect deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/235:50 pm
PTY
- CLT
2 stops18h 30m
Multiple Airlines
Wed 3/45:55 am
CLT
- PTY
2 stops18h 45m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$510
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/62:55 am
PTY
- CLT
2 stops42h 02m
Multiple Airlines
Sat 3/147:00 am
CLT
- PTY
1 stop13h 20m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$521
This Trip.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/62:55 am
PTY
- RDU
2 stops28h 22m
Multiple Airlines
Sat 4/1112:45 pm
RDU
- PTY
3 stops14h 10m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$532
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/192:28 pm
PTY
- GSO
1 stop8h 31m
Delta
Tue 3/315:19 am
GSO
- PTY
1 stop8h 44m
Delta
Deal found 2/11![Delta logo]()
$501
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/192:28 pm
PTY
- GSO
1 stop8h 31m
Delta
Mon 3/306:35 am
GSO
- PTY
1 stop7h 28m
Delta
Deal found 2/11![Delta logo]()
$510
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/191:40 pm
PTY
- GSO
2 stops20h 00m
American Airlines
Tue 4/77:20 pm
GSO
- PTY
2 stops18h 26m
American Airlines
Deal found 2/11![American Airlines logo]()
$515
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/192:28 pm
PTY
- GSO
1 stop8h 31m
Delta
Sun 3/297:57 pm
GSO
- PTY
1 stop18h 06m
Delta
Deal found 2/11![Delta logo]()
$524
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/192:28 pm
PTY
- GSO
1 stop8h 31m
Delta
Fri 4/107:57 pm
GSO
- PTY
1 stop18h 06m
Delta
Deal found 2/11![Delta logo]()
$531
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/191:40 pm
PTY
- GSO
2 stops20h 00m
American Airlines
Tue 3/317:46 pm
GSO
- PTY
2 stops17h 54m
American Airlines
Deal found 2/11![American Airlines logo]()
$537
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/192:28 pm
PTY
- GSO
1 stop8h 31m
Delta
Wed 4/15:19 am
GSO
- PTY
1 stop8h 44m
Delta
Deal found 2/11![Delta logo]()
$575
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/261:40 pm
PTY
- AVL
2 stops17h 42m
American Airlines
Tue 3/314:13 pm
AVL
- PTY
2 stops21h 27m
American Airlines
Deal found 2/9![American Airlines logo]()
$504
One-way flights from Panama to North CarolinaSearch for one-way flight options from Panama to North Carolina. Find affordable one-way fares based on user searches. Data last updated February 12, 2026.
Search for one-way flight options from Panama to North Carolina. Find affordable one-way fares based on user searches. Data last updated February 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/175:50 pm
PTY
- RDU
2 stops44h 47m
Multiple Airlines
Deal found 2/8![Multiple Airlines logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/85:30 am
PTY
- RDU
2 stops11h 25m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$302
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/241:49 pm
PTY
- ILM
2 stops21h 21m
American Airlines
Deal found 2/10![American Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/54:05 pm
PTY
- MYR
2 stops20h 08m
American Airlines
Deal found 2/9![American Airlines logo]()
$320
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:30 am
PTY
- RDU
3 stops17h 45m
Multiple Airlines
Deal found 2/8![Multiple Airlines logo]()
$320
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/252:40 pm
PTY
- ILM
2 stops24h 11m
American Airlines
Deal found 2/8![American Airlines logo]()
$325
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/235:50 pm
PTY
- CLT
3 stops44h 01m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$325
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/249:45 am
PTY
- CLT
1 stop10h 30m
United Airlines
Deal found 2/9![United Airlines logo]()
$332
This Delta deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/253:15 pm
PTY
- OAJ
1 stop7h 20m
Delta
Deal found 2/8![Delta logo]()
$341
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/189:21 pm
PTY
- RDU
2 stops34h 46m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$346
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/242:55 am
PTY
- ILM
3 stops30h 00m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/14:05 pm
PTY
- GSO
2 stops20h 02m
American Airlines
Deal found 2/11![American Airlines logo]()
$352
Find flight deals from Panama to North Carolina
Keep the following information in mind while searching for Panama to North Carolina flight deals. Data was last updated February 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $442 (American Airlines) |
One-way from | $285 (Kiwi.com) |
Popular in | January |
Cheapest in | September |
Average price | $575 |
Good one-way deal | $604 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama to North Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
Use the filters below to find and compare flights from Panama to North Carolina that are best for you.
Fly from
Panama
Fly to
North Carolina
Route
Depart
Return
Price
Panama CityCharlotte
PTY - CLT
PTYCLT
Panama City Tocumen Intl
Fri 5/1
1:49 pm-10:00 am
1 stop19h 11m
Charlotte Douglas
Fri 5/15
5:05 am-12:46 pm
1 stop8h 41m
$467
Panama CityRaleigh
PTY - RDU
PTYRDU
Panama City Tocumen Intl
Thu 4/23
9:33 pm-7:33 am
1 stop9h 00m
Raleigh-Durham
Tue 5/5
4:07 pm-8:06 am
2 stops16h 59m
$477
Panama CityGreensboro
PTY - GSO
PTYGSO
Panama City Tocumen Intl
Thu 3/19
2:28 pm-11:59 pm
1 stop8h 31m
Greensboro/H. Point
Tue 3/31
5:19 am-1:03 pm
1 stop8h 44m
$501
Panama CityCharlotte
PTY - CLT
PTYCLT
Panama City Tocumen Intl
Thu 4/30
1:49 pm-10:57 pm
1 stop8h 08m
Charlotte Douglas
Thu 5/14
8:45 pm-12:46 pm
1 stop17h 01m
$502
Panama CityRaleigh
PTY - RDU
PTYRDU
Panama City Tocumen Intl
Thu 4/30
2:27 pm-12:18 am
1 stop8h 51m
Raleigh-Durham
Sat 5/2
7:25 am-1:02 pm
1 stop6h 37m
$504
Panama CityAsheville
PTY - AVL
PTYAVL
Panama City Tocumen Intl
Thu 3/26
1:40 pm-8:22 am
2 stops17h 42m
Asheville Regional
Tue 3/31
4:13 pm-12:40 pm
2 stops21h 27m
$504
Panama CityCharlotte
PTY - CLT
PTYCLT
Panama City Tocumen Intl
Mon 2/23
9:33 pm-12:20 pm
1 stop14h 47m
Charlotte Douglas
Wed 3/4
7:00 am-4:06 pm
1 stop9h 06m
$510
Panama CityGreensboro
PTY - GSO
PTYGSO
Panama City Tocumen Intl
Thu 3/19
2:28 pm-11:59 pm
1 stop8h 31m
Greensboro/H. Point
Mon 3/30
6:35 am-1:03 pm
1 stop7h 28m
$510
Panama CityRaleigh
PTY - RDU
PTYRDU
Panama City Tocumen Intl
Mon 5/4
8:57 am-2:29 pm
Nonstop4h 32m
Raleigh-Durham
Sun 5/10
4:19 pm-7:46 pm
Nonstop4h 27m
$514
Panama CityGreensboro
PTY - GSO
PTYGSO
Panama City Tocumen Intl
Thu 3/19
1:40 pm-10:40 am
2 stops20h 00m
Greensboro/H. Point
Tue 4/7
7:20 pm-12:46 pm
2 stops18h 26m
$515
Showing 1-10 of 47 results
Best time to book a flight from Panama to North Carolina
Have a flexible travel schedule? Discover the best time to fly to North Carolina from Panama with our price prediction graph.
PTY-CLT
PTY-RDU
PTY-GSO
PTY-AVL
PTY-ILM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama to North Carolina
PA0-USNC
PTY-CLT
PTY-RDU
PTY-GSO
PTY-AVL
What is the cheapest month to book a flight from Panama to North Carolina?
Currently, June is the cheapest month in which you can book a flight from Panama to North Carolina (average of $273). Flying from Panama to North Carolina in January is currently the most expensive (average of $553). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PA to NC?
Find hourly flight availability from Panama to North Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 12, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama to North Carolina as you normally would.
Reviews of airlines servicing North Carolina
Get insights into the airlines that provide service to North Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to North Carolina. Reviews last updated February 12, 2026.
Read through reviews of airlines operating flights from Panama to North Carolina, such as Delta, Copa Airlines, and United Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Crew
8.5
Boarding
8.1
Comfort
7.9
Food
7.2
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Entertainment
7.8
Crew
8.5
Boarding
8.1
Comfort
7.9
Food
7.2
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Entertainment
7.8
Crew
8.5
Boarding
8.1
Comfort
7.9
Food
7.2
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Entertainment
7.8
Crew
8.5
Boarding
8.1
Comfort
7.9
Food
7.2
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Entertainment
7.8
Crew
8.5
Boarding
8.1
Comfort
7.9
Food
7.2
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Panama to North Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Panama to North Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to North Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Panama to North Carolina by cabin class
Find flights from Panama to North Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Panama and North Carolina flights
Browse other Panama and North Carolina flight options. Last updated on February 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from North Carolina
Find the right flight back to Panama after your stay in North Carolina
Panama to North Carolina flights
Consider these flights traveling from Panama to North Carolina.
Top 4 airlines flying from Panama to North Carolina
Discover the top 4 airlines that operate flights from Panama to North Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$291 | Average$510 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$355 | Average$496 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$370 | Average$506 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$425 | Average$645 | FlexibilityNo cancel fee | On-time69% |