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$279+ Cheap flights from Panama to North Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/5. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — RDU
oct. 25 — nov. 11
sáb. 10/25
sáb. 11/1
1 adult, Economy
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Cheap flight deals from Panama to North Carolina

Keep the following information in mind while searching for Panama to North Carolina flight deals. Data was last updated septiembre 25, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$383
(Avianca Connect)

One-way from

$279
(Trip.com)

Popular in

April

Cheapest in

September

Average price

$385

Good round-trip deal

$494 or less
Provider with most accurate pricing for Panama City Tocumen Intl-Raleigh-Durham flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Raleigh-Durham flights.
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From Panama to North Carolina
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One-way flight from Panama to North Carolina
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Highest demand for flights based on searches. 3% potential increase in price ($15 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Panama to North Carolina.
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Find flight deals from Panama to North Carolina

Cheapest flights from Panama to North Carolina
Explore the most affordable flight options available from Panama to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 25, 2025.

This Avianca Connect deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/155:25 pmPTY - CLT
2 stops18h 14mMultiple Airlines
mié. 10/225:45 amCLT - PTY
2 stops16h 25mMultiple Airlines
Deal found 9/24$383
This Avianca Connect deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/235:25 pmPTY - CLT
2 stops18h 14mMultiple Airlines
mié. 11/125:45 amCLT - PTY
2 stops18h 55mMultiple Airlines
Deal found 9/25$389
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/34:41 pmPTY - CLT
1 stop29h 18mUnited Airlines
mar. 1/136:45 amCLT - PTY
1 stop10h 22mUnited Airlines
Deal found 9/25$404
This Avianca Connect deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/235:25 pmPTY - CLT
2 stops18h 14mMultiple Airlines
jue. 10/301:49 pmCLT - PTY
2 stops12h 11mMultiple Airlines
Deal found 9/24$410
This Copa Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/178:57 amPTY - RDU
Nonstop4h 28mCopa Airlines
mié. 12/313:11 pmRDU - PTY
Nonstop4h 35mCopa Airlines
Deal found 9/23$413
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/182:49 pmPTY - CLT
1 stop17h 01mAmerican Airlines
mar. 11/255:15 amCLT - PTY
1 stop8h 28mAmerican Airlines
Deal found 9/24$422
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/172:50 pmPTY - RDU
1 stop20h 06mAmerican Airlines
mié. 12/317:57 pmRDU - PTY
1 stop19h 57mAmerican Airlines
Deal found 9/23$436
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/214:55 pmPTY - RDU
2 stops19h 07mAmerican Airlines
mié. 12/316:37 amRDU - PTY
2 stops9h 17mAmerican Airlines
Deal found 9/23$438
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/2611:35 amPTY - CLT
1 stop23h 02mUnited Airlines
vie. 1/26:23 amCLT - PTY
1 stop13h 15mUnited Airlines
Deal found 9/24$447
This Delta deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/228:00 amPTY - CLT
1 stop11h 09mDelta
lun. 1/55:30 amCLT - PTY
1 stop8h 25mDelta
Deal found 9/25$453
This Copa Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/278:57 amPTY - RDU
Nonstop4h 28mCopa Airlines
dom. 1/43:09 pmRDU - PTY
Nonstop4h 37mCopa Airlines
Deal found 9/23$454
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/2812:03 pmPTY - CLT
1 stop10h 25mMultiple Airlines
mar. 11/45:45 amCLT - PTY
1 stop14h 34mMultiple Airlines
Deal found 9/24$458

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to North Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 25, 2025.
Use the filters below to find and compare flights from Panama to North Carolina that are best for you.

Fly from

Panama

Fly to

North Carolina

Route

Depart

Return

Price

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

mié. 10/15

5:25 pm-12:39 pm

2 stops18h 14m

Charlotte Douglas

mié. 10/22

5:45 am-9:10 pm

2 stops16h 25m

$383

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

jue. 10/23

5:25 pm-12:39 pm

2 stops18h 14m

Charlotte Douglas

mié. 11/12

5:45 am-12:40 am

2 stops18h 55m

$389

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

mié. 12/3

4:41 pm-9:59 pm

1 stop29h 18m

Charlotte Douglas

mar. 1/13

6:45 am-5:07 pm

1 stop10h 22m

$404

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

mié. 12/3

11:35 am-9:59 pm

1 stop10h 24m

Charlotte Douglas

mié. 12/10

6:45 am-2:45 pm

1 stop8h 00m

$404

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

jue. 10/23

5:25 pm-12:39 pm

2 stops18h 14m

Charlotte Douglas

jue. 10/30

1:49 pm-1:00 am

2 stops12h 11m

$410

Panama CityRaleigh

PTY - RDU

PTYRDU

Panama City Tocumen Intl

mié. 12/17

8:57 am-1:25 pm

Nonstop4h 28m

Raleigh-Durham

mié. 12/31

3:11 pm-7:46 pm

Nonstop4h 35m

$413

Panama CityRaleigh

PTY - RDU

PTYRDU

Panama City Tocumen Intl

mié. 12/17

2:50 pm-10:56 am

1 stop20h 06m

Raleigh-Durham

mié. 12/31

7:57 pm-3:54 pm

1 stop19h 57m

$436

Panama CityRaleigh

PTY - RDU

PTYRDU

Panama City Tocumen Intl

dom. 12/21

4:55 pm-12:02 pm

2 stops19h 07m

Raleigh-Durham

mié. 12/31

5:00 am-3:54 pm

1 stop10h 54m

$438

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

vie. 12/26

11:35 am-10:37 am

1 stop23h 02m

Charlotte Douglas

vie. 1/2

6:23 am-7:38 pm

1 stop13h 15m

$447

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

lun. 12/22

8:00 am-7:09 pm

1 stop11h 09m

Charlotte Douglas

lun. 1/5

5:30 am-1:55 pm

1 stop8h 25m

$453

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/24

Showing 1-10 of 51 results
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Best time to book a flight from Panama to North Carolina

Have a flexible travel schedule? Discover the best time to fly to North Carolina from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to North Carolina

What is the cheapest month to book a flight from Panama to North Carolina?

Currently, August is the cheapest month in which you can book a flight from Panama to North Carolina (average of $206). Flying from Panama to North Carolina in March is currently the most expensive (average of $293). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to NC?

Find hourly flight availability from Panama to North Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 25, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama to North Carolina as you normally would.

Reviews of airlines servicing North Carolina

Get insights into the airlines that provide service to North Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to North Carolina. Reviews last updated septiembre 25, 2025.
Read through reviews of airlines operating flights from Panama to North Carolina, such as Delta, Copa Airlines, and United Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,973 reviews

Boarding

8.2

Crew

8.5

Overall

8.0

Comfort

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others
Delta
8.0
Very good
7,973 reviews
Delta
8.0
Very good
7,973 reviews

Boarding

8.2

Crew

8.5

Overall

8.0

Comfort

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others
Copa Airlines
7.6
Good
1,539 reviews
Delta
8.0
Very good
7,973 reviews

Boarding

8.2

Crew

8.5

Overall

8.0

Comfort

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others
United Airlines
7.4
Good
8,926 reviews
Delta
8.0
Very good
7,973 reviews

Boarding

8.2

Crew

8.5

Overall

8.0

Comfort

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,973 reviews

Boarding

8.2

Crew

8.5

Overall

8.0

Comfort

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others

Related info for your journey

Find useful and relevant information for your journey from Panama to North Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Panama to North Carolina flight route?

    The Panama to North Carolina flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Panama to North Carolina?

    There are many flights that can get you from Panama to North Carolina in 4h 28m. Fly via United Airlines, Copa Airlines, or American Airlines to get the fastest option. The distance between Panama and North Carolina is about 1851 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Panama to North Carolina that include hotel bookings?

    Yes. In addition to deals on Panama to North Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to North Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to North Carolina.

  • Can I find deals for business class flights from Panama to North Carolina?

    Yes. Cheapflights offers flight deals from Panama to North Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to North Carolina?

    Currently, August is the cheapest month in which you can book a flight from Panama to North Carolina (average of $206). Flying from Panama to North Carolina in March is currently the most expensive (average of $293). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama to North Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Panama to North Carolina

Discover the top 4 airlines that operate flights from Panama to North Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 25, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$298Average$444FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$312Average$494FlexibilityNo cancel feeOn-time71%
DeltaCheapest$361Average$538FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$436Average$531FlexibilityNo cancel feeOn-time69%

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