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North Carolina

$274+ Cheap flights from Panama to North Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/26. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — RDU
Dec 12 — Dec 191
Fri 12/12
Fri 12/19
1 adult, Economy
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Cheap flight deals from Panama to North Carolina

Keep the following information in mind while searching for Panama to North Carolina flight deals. Data was last updated November 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$380
(American Airlines)

One-way from

$274
(Kiwi.com)

Popular in

April

Cheapest in

September

Average price

$520

Good round-trip deal

$604 or less
Provider with most accurate pricing for Panama City Tocumen Intl-Raleigh-Durham flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Raleigh-Durham flights.
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From Panama to North Carolina
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One-way flight from Panama to North Carolina
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Highest demand for flights based on searches. 0% potential increase in price ($3 potential increase over avg. RT price).
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Cheapest flight prices on average. 0% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Price to beat on a round-trip flight from Panama to North Carolina.
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Find flight deals from Panama to North Carolina

Cheapest flights from Panama to North Carolina
Explore the most affordable flight options available from Panama to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 12, 2025.

This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/204:55 pmPTY - RDU
2 stops17h 39mAmerican Airlines
Sun 1/48:17 pmRDU - PTY
2 stops17h 36mAmerican Airlines
Deal found 11/12$380
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/164:43 pmPTY - AVL
2 stops17h 14mAmerican Airlines
Wed 12/316:00 amAVL - PTY
1 stop9h 54mAmerican Airlines
Deal found 11/11$491
This Copa Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/178:57 amPTY - RDU
Nonstop4h 28mCopa Airlines
Sun 1/43:09 pmRDU - PTY
Nonstop4h 37mCopa Airlines
Deal found 11/12$495
This Avianca Connect deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/142:55 amPTY - CLT
2 stops17h 57mMultiple Airlines
Sat 11/228:52 pmCLT - PTY
2 stops17h 08mMultiple Airlines
Deal found 11/10$500
This Delta deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/173:46 pmPTY - RDU
1 stop8h 32mDelta
Sun 1/46:30 amRDU - PTY
1 stop13h 30mDelta
Deal found 11/12$501
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/294:41 pmPTY - CLT
1 stop29h 01mUnited Airlines
Mon 1/56:22 amCLT - PTY
1 stop13h 16mUnited Airlines
Deal found 11/12$503
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/218:55 amPTY - RDU
1 stop13h 04mUnited Airlines
Wed 12/316:31 amRDU - PTY
2 stops13h 07mUnited Airlines
Deal found 11/10$510
This Copa Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/218:57 amPTY - RDU
Nonstop4h 28mCopa Airlines
Sun 1/43:09 pmRDU - PTY
Nonstop4h 37mCopa Airlines
Deal found 11/10$511
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/258:55 amPTY - CLT
1 stop12h 47mUnited Airlines
Thu 1/16:10 amCLT - PTY
1 stop8h 35mUnited Airlines
Deal found 11/10$512
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/162:50 pmPTY - AVL
2 stops19h 07mAmerican Airlines
Tue 12/308:04 pmAVL - PTY
2 stops17h 49mAmerican Airlines
Deal found 11/11$512
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/174:43 pmPTY - RDU
2 stops19h 19mAmerican Airlines
Sun 1/47:01 pmRDU - PTY
2 stops18h 52mAmerican Airlines
Deal found 11/12$514
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/252:53 pmPTY - CLT
2 stops15h 40mAmerican Airlines
Thu 1/110:45 pmCLT - PTY
1 stop15h 08mAmerican Airlines
Deal found 11/10$516

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to North Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 12, 2025.
Use the filters below to find and compare flights from Panama to North Carolina that are best for you.

Fly from

Panama

Fly to

North Carolina

Route

Depart

Return

Price

Panama CityRaleigh

PTY - RDU

PTYRDU

Panama City Tocumen Intl

Sat 12/20

4:55 pm-10:34 am

2 stops17h 39m

Raleigh-Durham

Sun 1/4

8:17 pm-1:53 pm

2 stops17h 36m

$380

Panama CityGreensboro

PTY - GSO

PTYGSO

Panama City Tocumen Intl

Sat 5/9

2:20 pm-11:57 pm

1 stop8h 37m

Greensboro/H. Point

Wed 5/13

5:25 am-12:55 pm

1 stop8h 30m

$418

Panama CityJacksonville

PTY - OAJ

PTYOAJ

Panama City Tocumen Intl

Wed 2/11

2:27 pm-3:45 pm

2 stops25h 18m

Jacksonville Albert J Ellis

Fri 2/20

4:10 pm-3:14 pm

2 stops23h 04m

$491

Panama CityAsheville

PTY - AVL

PTYAVL

Panama City Tocumen Intl

Tue 12/16

2:50 pm-10:57 am

2 stops20h 07m

Asheville Regional

Wed 12/31

6:18 pm-3:54 pm

2 stops21h 36m

$491

Panama CityAsheville

PTY - AVL

PTYAVL

Panama City Tocumen Intl

Tue 12/16

2:50 pm-10:57 am

2 stops20h 07m

Asheville Regional

Tue 12/30

8:04 pm-3:54 pm

2 stops19h 50m

$491

Panama CityWilmington

PTY - ILM

PTYILM

Panama City Tocumen Intl

Fri 5/1

2:20 pm-3:36 pm

1 stop24h 16m

Wilmington New Hanover County

Tue 5/5

6:00 am-12:55 pm

1 stop7h 55m

$492

Panama CityMyrtle Beach

PTY - MYR

PTYMYR

Panama City Tocumen Intl

Fri 5/8

2:20 pm-10:09 am

1 stop18h 49m

Myrtle Beach Intl

Mon 5/11

7:50 pm-12:55 pm

1 stop18h 05m

$492

Panama CityRaleigh

PTY - RDU

PTYRDU

Panama City Tocumen Intl

Wed 12/17

8:57 am-1:25 pm

Nonstop4h 28m

Raleigh-Durham

Sat 1/3

3:09 pm-7:46 pm

Nonstop4h 37m

$495

Panama CityRaleigh

PTY - RDU

PTYRDU

Panama City Tocumen Intl

Wed 12/17

8:57 am-1:25 pm

Nonstop4h 28m

Raleigh-Durham

Sun 1/4

3:09 pm-7:46 pm

Nonstop4h 37m

$495

Panama CityRaleigh

PTY - RDU

PTYRDU

Panama City Tocumen Intl

Sat 2/21

4:41 pm-10:33 pm

1 stop29h 52m

Raleigh-Durham

Fri 3/6

6:30 am-7:38 pm

1 stop13h 08m

$501

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/11

Showing 1-10 of 52 results
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Best time to book a flight from Panama to North Carolina

Have a flexible travel schedule? Discover the best time to fly to North Carolina from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to North Carolina

What is the cheapest month to book a flight from Panama to North Carolina?

Currently, June is the cheapest month in which you can book a flight from Panama to North Carolina (average of $273). Flying from Panama to North Carolina in November is currently the most expensive (average of $426). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to NC?

Find hourly flight availability from Panama to North Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 12, 2025.

A simple way to save on the total cost of your ticket is to fly from Panama to North Carolina in the evening. If you’re flexible enough to do this you can expect to save up to 29% on your trip compared to booking a flight in the afternoon.

What is the cheapest day to fly from Panama to North Carolina?

Use this chart to determine the cheapest time to fly round-trip from Panama to North Carolina. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Panama to North Carolina flight should consider departing on Tuesday mornings when fares are most often at their lowest. Wednesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing North Carolina

Get insights into the airlines that provide service to North Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to North Carolina. Reviews last updated November 12, 2025.
Read through reviews of airlines operating flights from Panama to North Carolina, such as Delta, Copa Airlines, and United Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,008 reviews

Comfort

7.9

Food

7.3

Overall

7.9

Entertainment

7.9

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,008 reviews
Delta
7.9
Good
8,008 reviews

Comfort

7.9

Food

7.3

Overall

7.9

Entertainment

7.9

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Copa Airlines
7.6
Good
1,563 reviews
Delta
7.9
Good
8,008 reviews

Comfort

7.9

Food

7.3

Overall

7.9

Entertainment

7.9

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,015 reviews
Delta
7.9
Good
8,008 reviews

Comfort

7.9

Food

7.3

Overall

7.9

Entertainment

7.9

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,049 reviews
Delta
7.9
Good
8,008 reviews

Comfort

7.9

Food

7.3

Overall

7.9

Entertainment

7.9

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Panama to North Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Panama to North Carolina flight route?

    The Panama to North Carolina flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Panama to North Carolina?

    There are many flights that can get you from Panama to North Carolina in 4h 28m. Fly via American Airlines, Delta, or Copa Airlines to get the fastest option. The distance between Panama and North Carolina is about 1851 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Panama to North Carolina that include hotel bookings?

    Yes. In addition to deals on Panama to North Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to North Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to North Carolina.

  • Can I find deals for business class flights from Panama to North Carolina?

    Yes. Cheapflights offers flight deals from Panama to North Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to North Carolina?

    Currently, June is the cheapest month in which you can book a flight from Panama to North Carolina (average of $273). Flying from Panama to North Carolina in November is currently the most expensive (average of $426). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Panama to North Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Panama to North Carolina

Discover the top 4 airlines that operate flights from Panama to North Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$345Average$459FlexibilityNo cancel feeOn-time70%
DeltaCheapest$361Average$538FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$370Average$518FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$436Average$531FlexibilityNo cancel feeOn-time69%

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