Myrtle Beach

$204+ Cheap flights from Iowa to Myrtle Beach (MYR)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/14. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MYR
Jan 15 — Jan 221
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Cheap flight deals from Iowa to Myrtle Beach

Cheapest flights from Iowa to Myrtle Beach
Explore the most affordable flight options available from Iowa to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 16, 2025.

This Delta deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/195:08 pmMLI - MYR
1 stop5h 35mDelta
Thu 12/255:12 pmMYR - MLI
1 stop6h 18mDelta
Deal found 12/13$354
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/195:43 pmMLI - MYR
1 stop5h 12mAmerican Airlines
Sun 12/215:11 pmMYR - MLI
1 stop6h 40mAmerican Airlines
Deal found 12/15$369
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/248:31 amDSM - MYR
2 stops8h 37mMultiple Airlines
Wed 12/316:00 amMYR - DSM
1 stop8h 54mMultiple Airlines
Deal found 12/16$424
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/215:43 pmMLI - MYR
1 stop5h 12mAmerican Airlines
Sun 12/286:00 amMYR - MLI
2 stops9h 05mAmerican Airlines
Deal found 12/16$436
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/192:35 pmMLI - MYR
2 stops6h 57mAmerican Airlines
Thu 12/2512:48 pmMYR - MLI
2 stops11h 03mAmerican Airlines
Deal found 12/13$456
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/248:31 amDSM - MYR
2 stops8h 37mMultiple Airlines
Tue 12/309:54 amMYR - DSM
1 stop14h 16mMultiple Airlines
Deal found 12/16$466
This Delta deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/215:50 amMLI - MYR
1 stop5h 41mDelta
Thu 1/15:12 pmMYR - MLI
1 stop6h 18mDelta
Deal found 12/15$479
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/215:43 pmMLI - MYR
1 stop5h 12mAmerican Airlines
Thu 1/16:00 amMYR - MLI
2 stops9h 05mAmerican Airlines
Deal found 12/15$481
This Delta deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2012:08 pmDSM - MYR
2 stops9h 42mDelta
Wed 12/3111:27 amMYR - DSM
1 stop6h 25mDelta
Deal found 12/16$513
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:41 amDSM - MYR
1 stop6h 23mAmerican Airlines
Wed 12/312:34 pmMYR - DSM
1 stop4h 47mAmerican Airlines
Deal found 12/15$543
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/248:31 amDSM - MYR
2 stops8h 37mMultiple Airlines
Mon 12/296:00 amMYR - DSM
1 stop7h 55mMultiple Airlines
Deal found 12/16$549
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1711:15 amDSM - MYR
1 stop20h 34mMultiple Airlines
Tue 12/239:54 amMYR - DSM
1 stop14h 16mMultiple Airlines
Deal found 12/16$555

Find flight deals from Iowa to Myrtle Beach

Keep the following information in mind while searching for Iowa to Myrtle Beach flight deals. Data was last updated December 16, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$238
(Kiwi.com)

One-way from

$204
(American Airlines)

Popular in

June

Cheapest in

August

Average price

$373
Provider with most accurate pricing for Des Moines-Myrtle Beach Intl flight deals.
Provider most trusted by Cheapflights users for Des Moines-Myrtle Beach Intl flights.
From Iowa to Myrtle Beach Intl
One-way flight from Iowa to Myrtle Beach Intl
Highest demand for flights based on searches. 9% potential increase in price ($39 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
Average for round-trip flights in December 2025

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Myrtle Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 16, 2025.
Use the filters below to find and compare flights from Iowa to Myrtle Beach that are best for you.

Fly from

Iowa

Fly to

Myrtle Beach

Route

Depart

Return

Price

MolineMyrtle Beach

MLI - MYR

MLIMYR

Moline Quad-City

Sun 1/4

5:43 pm-11:55 pm

1 stop5h 12m

Myrtle Beach Intl

Sun 1/11

5:29 pm-9:33 pm

1 stop5h 04m

$274

Cedar RapidsMyrtle Beach

CID - MYR

CIDMYR

Cedar Rapids

Thu 1/1

6:40 am-2:04 pm

1 stop6h 24m

Myrtle Beach Intl

Sat 2/14

7:56 pm-11:58 pm

1 stop5h 02m

$283

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Thu 1/29

4:30 pm-2:42 pm

2 stops21h 12m

Myrtle Beach Intl

Thu 2/5

10:00 am-10:46 pm

2 stops13h 46m

$310

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Thu 1/29

6:00 am-2:55 pm

1 stop7h 55m

Myrtle Beach Intl

Thu 2/5

5:29 pm-11:08 pm

1 stop6h 39m

$320

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Mon 2/2

7:40 am-1:23 pm

1 stop4h 43m

Myrtle Beach Intl

Mon 2/16

5:18 pm-11:47 pm

1 stop7h 29m

$353

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Sat 2/28

12:25 pm-11:57 pm

2 stops10h 32m

Myrtle Beach Intl

Sun 3/8

6:00 am-10:39 am

1 stop5h 39m

$357

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Mon 2/2

6:10 am-2:25 pm

2 stops7h 15m

Myrtle Beach Intl

Mon 2/16

10:35 am-10:35 pm

2 stops13h 00m

$363

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Mon 1/5

12:56 pm-7:12 pm

1 stop5h 16m

Myrtle Beach Intl

Thu 1/8

3:30 pm-10:11 pm

1 stop7h 41m

$371

Cedar RapidsMyrtle Beach

CID - MYR

CIDMYR

Cedar Rapids

Mon 3/2

5:33 am-1:33 pm

1 stop7h 00m

Myrtle Beach Intl

Sun 3/8

6:00 am-3:34 pm

2 stops10h 34m

$383

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Mon 3/2

5:24 am-1:33 pm

1 stop7h 09m

Myrtle Beach Intl

Fri 3/6

12:15 pm-7:33 pm

1 stop8h 18m

$387

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Showing 1-10 of 34 results
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Best time to book a flight from Iowa to Myrtle Beach

Have a flexible travel schedule? Discover the best time to fly to Myrtle Beach from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Myrtle Beach

What is the cheapest month to book a flight from Iowa to Myrtle Beach?

Currently, May is the cheapest month in which you can book a flight from Iowa to Myrtle Beach (average of $166). Flying from Iowa to Myrtle Beach in December is currently the most expensive (average of $266). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Myrtle Beach. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Myrtle Beach from Iowa?

    Located just 2.1 mi from the city center, Myrtle Beach Intl (MYR) is the airport most travelers will use when flying to Myrtle Beach from Iowa.

  • How long is the flight from Iowa to Myrtle Beach?

    Airlines like American Airlines, Delta, and Southwest fly from Iowa to Myrtle Beach in about 4h 05m. The time it takes to get you to your destination can typically vary by up to 6h 27m. Iowa and Myrtle Beach are separated by a distance of 1066 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Iowa to Myrtle Beach?

  • Can I find deals for flights from Iowa to Myrtle Beach that include hotel bookings?

    Yes. In addition to deals on Iowa to Myrtle Beach flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Myrtle Beach?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Myrtle Beach.

  • Can I find deals for business class flights from Iowa to Myrtle Beach?

    Yes. Cheapflights offers flight deals from Iowa to Myrtle Beach by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Myrtle Beach?

    Currently, May is the cheapest month in which you can book a flight from Iowa to Myrtle Beach (average of $166). Flying from Iowa to Myrtle Beach in December is currently the most expensive (average of $266). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Myrtle Beach?

Book flights to Myrtle Beach if you plan to visit one of these locations
Conway
Surfside Beach
Little River
Pawleys Island
Ocean Isle Beach
Garden City Beach

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Alternative routes for Iowa to Myrtle Beach

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Iowa to Myrtle Beach

Discover the top 4 airlines that operate flights from Iowa to Myrtle Beach. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$235Average$393FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$248Average$368FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$272Average$404FlexibilityNo cancel feeOn-time63%
DeltaCheapest$273Average$369FlexibilityNo cancel feeOn-timeN/A

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