In terms of precipitation, rainfall in Florence, Alabama ranges from 2.9 - 6.1 inches per month. March is typically the wettest month, when rainfall can reach 6.1 in. October is typically the driest time to visit Florence, Alabama when rainfall is around 2.9 in.

If weather is an important factor for your trip to Florence, Alabama, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

What is the cheapest time of day to fly from CO to MSL?

When flying from Colorado to Florence, Alabama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What airport do you fly into for flights to Florence from Colorado?

Florence Muscle Shoals (MSL) is the airport you will fly into if you book a flight from Colorado to Florence. It is only a 5.4 mi journey from Muscle Shoals (MSL) to Florence’s city center.

Can I find deals for flights from Colorado to Florence that include hotel bookings?

Yes. In addition to deals on Colorado to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Colorado to Florence?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Colorado to Florence.

Can I find deals for business class flights from Colorado to Florence?

Yes. Cheapflights offers flight deals from Colorado to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$479+ Cheap Flights from Colorado to Florence, AL

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Explore the most affordable flight options available from Colorado to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 27, 2026.

Fri 8/2811:00 am

DEN

MSL

1 stop6h 50m

Multiple Airlines

Sun 8/3012:45 pm

MSL

DEN

2 stops20h 29m

Multiple Airlines

Deal found 7/25

$479

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Round-trip from	$479 (Kiwi.com)

From Colorado to Florence Muscle Shoals

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DenverFlorence

DEN - MSL

DENMSL

Denver Intl

Fri 8/28

11:00 am-6:50 pm

1 stop6h 50m

Florence Muscle Shoals

Sun 8/30

12:45 pm-8:14 am

2 stops20h 29m

$479

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Related info for your journey

What airport do you fly into for flights to Florence from Colorado?
Florence Muscle Shoals (MSL) is the airport you will fly into if you book a flight from Colorado to Florence. It is only a 5.4 mi journey from Muscle Shoals (MSL) to Florence’s city center.
Can I find deals for flights from Colorado to Florence that include hotel bookings?
Yes. In addition to deals on Colorado to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Colorado to Florence?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Colorado to Florence.
Can I find deals for business class flights from Colorado to Florence?
Yes. Cheapflights offers flight deals from Colorado to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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$479+ Cheap flights from Colorado to Florence, AL (MSL)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/28. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Colorado to Florence with Cheapflights

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Cheap flight deals from Colorado to Florence

Cheapest flights from Colorado to FlorenceExplore the most affordable flight options available from Colorado to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 27, 2026.

Explore the most affordable flight options available from Colorado to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 27, 2026.

Best flights from Colorado to FlorenceDiscover carefully curated flight deals from Colorado to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 27, 2026.

Discover carefully curated flight deals from Colorado to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 27, 2026.

Last-minute flights from Colorado to FlorenceDiscover last-minute flight deals from Colorado to Florence. Data last updated July 27, 2026 and is based on user searches.

Discover last-minute flight deals from Colorado to Florence. Data last updated July 27, 2026 and is based on user searches.

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Related info for your journey

What airport do you fly into for flights to Florence from Colorado?

Can I find deals for flights from Colorado to Florence that include hotel bookings?

How can I find direct flights from Colorado to Florence?

Can I find deals for business class flights from Colorado to Florence?

Traveling to a place near Florence?

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Cheapest flights from Colorado to Florence
Explore the most affordable flight options available from Colorado to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 27, 2026.

Best flights from Colorado to Florence
Discover carefully curated flight deals from Colorado to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 27, 2026.

Last-minute flights from Colorado to Florence
Discover last-minute flight deals from Colorado to Florence. Data last updated July 27, 2026 and is based on user searches.