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$286+ Cheap flights from Des Moines to Mobile (DSM - MOB)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/21. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MOB
Apr 9 — Apr 161
Thu 4/9
Thu 4/16
1 adult, Economy
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Cheap flight deals from Des Moines to Mobile

Cheapest flights from Des Moines to Mobile
Explore the most affordable flight options available from Des Moines to Mobile. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.

This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:13 pm
DSM
-
MOB
1 stop4h 46m
American Airlines
Tue 4/285:22 am
MOB
-
DSM
1 stop6h 04m
American Airlines
Deal found 3/7$286
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:20 pm
DSM
-
MOB
1 stop6h 08m
Delta
Wed 4/86:15 am
MOB
-
DSM
1 stop4h 33m
Delta
Deal found 3/9$289
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/141:10 pm
DSM
-
MOB
2 stops8h 49m
United Airlines
Sat 4/187:00 am
MOB
-
DSM
2 stops9h 15m
United Airlines
Deal found 3/5$300
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:45 am
DSM
-
MOB
1 stop5h 44m
Delta
Wed 10/76:00 am
MOB
-
DSM
1 stop4h 18m
Delta
Deal found 3/9$309
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:20 am
DSM
-
MOB
2 stops9h 26m
Delta
Wed 9/96:00 am
MOB
-
DSM
1 stop4h 14m
Delta
Deal found 3/9$314
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/58:20 am
DSM
-
MOB
1 stop8h 00m
United Airlines
Sat 4/114:55 pm
MOB
-
DSM
1 stop5h 48m
United Airlines
Deal found 3/8$319
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:30 pm
DSM
-
MOB
1 stop4h 25m
Delta
Thu 8/136:00 am
MOB
-
DSM
1 stop4h 14m
Delta
Deal found 3/8$324
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/2111:34 am
DSM
-
MOB
1 stop7h 18m
American Airlines
Sat 3/2810:48 am
MOB
-
DSM
1 stop8h 09m
American Airlines
Deal found 3/9$329

Find flight deals from Des Moines to Mobile

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Mobile (MOB). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 10, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$286
(American Airlines)

Popular in

December

Cheapest in

October

Average price

$493
Provider with most accurate pricing for Des Moines-Mobile flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Mobile flights.
Search Deals
From Des Moines to Mobile
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($68 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 11% potential price decrease ($41 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Mobile that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
Use the filters below to find and compare flights from Des Moines to Mobile that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Wed 4/1

5:35 am-11:55 am

1 stop6h 20m

Mobile

Wed 4/8

6:15 am-4:54 pm

2 stops10h 39m

$294
Quickest round-trip

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Sun 8/30

6:30 pm-10:55 pm

1 stop4h 25m

Mobile

Sun 9/6

6:00 am-10:14 am

1 stop4h 14m

$309

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Tue 5/12

5:00 am-6:05 pm

2 stops13h 05m

Mobile

Sat 5/16

4:55 pm-10:45 pm

1 stop5h 50m

$364

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Tue 8/25

11:23 am-9:29 pm

2 stops10h 06m

Mobile

Sat 8/29

9:30 am-2:17 pm

1 stop4h 47m

$364

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Sat 8/22

6:00 am-4:09 pm

2 stops10h 09m

Mobile

Wed 8/26

11:35 am-8:17 pm

2 stops8h 42m

$369

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Tue 9/1

1:40 pm-9:29 pm

2 stops7h 49m

Mobile

Wed 9/9

11:35 am-12:34 am

2 stops12h 59m

$389
Cheapest one-way
Quickest one-way

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Fri 3/20

5:20 pm-11:28 pm

1 stop6h 08m

$314

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Fri 3/20

1:48 pm-11:51 pm

2 stops10h 03m

$349

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/6

Sorted by cheapest first

Compare providers for flights from Des Moines to Mobile

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Mobile in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Mobile flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Mobile flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Mobile flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Mobile flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Mobile flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Mobile

Have a flexible travel schedule? Discover the best time to fly to Mobile from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Mobile

What is the cheapest month to book a flight from Des Moines to Mobile?

Currently, November is the cheapest month in which you can book a flight from Des Moines to Mobile (average of $100). Flying from Des Moines to Mobile in May is currently the most expensive (average of $231). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Mobile

Get insights into the airlines that provide service to Mobile. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mobile. Reviews last updated March 10, 2026.
Read reviews from past customers who have flown Delta,United Airlines, andAmerican Airlines from Des Moines to Mobile. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,276 reviews

Food

7.2

Entertainment

7.8

Crew

8.5

Comfort

7.9

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,276 reviews
Delta
7.9
Good
8,276 reviews

Food

7.2

Entertainment

7.8

Crew

8.5

Comfort

7.9

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,409 reviews
Delta
7.9
Good
8,276 reviews

Food

7.2

Entertainment

7.8

Crew

8.5

Comfort

7.9

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,413 reviews
Delta
7.9
Good
8,276 reviews

Food

7.2

Entertainment

7.8

Crew

8.5

Comfort

7.9

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Mobile. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Mobile?

    Delta and United Airlines can get you from Des Moines to Mobile in just under 6h 20m. Your travel time can differ by up to 6h 45m. Airlines will cover a distance of 807 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Des Moines to Mobile round-trip?

    American Airlines, at $248, was found to be the cheapest airline from Des Moines to Mobile.Alternate airlines to your destination round-trip include Delta and United Airlines. These flights start at 36% lower than the current average price 3 months from now.

  • Can I find deals for flights from Des Moines to Mobile that include hotel bookings?

    Yes. In addition to deals on Des Moines to Mobile flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Mobile?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Mobile.

  • Can I find deals for business class flights from Des Moines to Mobile?

    Yes. Cheapflights offers flight deals from Des Moines to Mobile by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Mobile?

    Currently, November is the cheapest month in which you can book a flight from Des Moines to Mobile (average of $100). Flying from Des Moines to Mobile in May is currently the most expensive (average of $231). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Mobile?

Book flights to Mobile if you plan to visit one of these locations
Pascagoula
Moss Point

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Des Moines to Mobile

Discover the top 3 airlines that operate flights from Des Moines to Mobile. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$354FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$438FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$258Average$314FlexibilityNo cancel feeOn-time69%

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