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$234+ Cheap flights from Des Moines to Mobile (DSM - MOB)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/31. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MOB
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Des Moines to Mobile

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Mobile (MOB). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$249
(Delta)

One-way from

$234
(Delta)

Popular in

October

Cheapest in

September

Average price

$234
From Des Moines to Mobile
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One-way flight from Des Moines to Mobile
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Highest demand for flights based on searches. 10% potential increase in price ($42 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($24 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Des Moines to Mobile

Cheapest flights from Des Moines to Mobile
Explore the most affordable flight options available from Des Moines to Mobile. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/86:39 pmDSM - MOB
1 stop4h 09mDelta
Wed 10/155:43 amMOB - DSM
1 stop4h 22mDelta
Deal found 9/10$249
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/85:00 amDSM - MOB
2 stops8h 16mAmerican Airlines
Wed 10/156:21 pmMOB - DSM
1 stop4h 55mAmerican Airlines
Deal found 9/10$254
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2512:30 pmDSM - MOB
2 stops10h 18mDelta
Sat 11/15:43 amMOB - DSM
2 stops11h 09mDelta
Deal found 9/10$259
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/236:30 pmDSM - MOB
1 stop4h 42mDelta
Tue 9/304:43 pmMOB - DSM
1 stop5h 54mDelta
Deal found 9/10$284
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/236:00 amDSM - MOB
2 stops10h 33mAmerican Airlines
Tue 9/301:52 pmMOB - DSM
2 stops9h 21mAmerican Airlines
Deal found 9/10$294
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/313:30 pmDSM - MOB
2 stops7h 18mDelta
Thu 11/61:17 pmMOB - DSM
1 stop4h 27mDelta
Deal found 9/11$299
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/166:15 amDSM - MOB
1 stop5h 28mUnited Airlines
Sat 9/209:18 amMOB - DSM
1 stop4h 59mUnited Airlines
Deal found 9/9$309
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/146:11 pmDSM - MOB
1 stop5h 48mAmerican Airlines
Sun 9/215:52 pmMOB - DSM
1 stop5h 38mAmerican Airlines
Deal found 9/9$324
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/166:00 amDSM - MOB
2 stops9h 58mDelta
Sat 9/209:10 amMOB - DSM
1 stop7h 12mDelta
Deal found 9/10$329

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Mobile that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Des Moines to Mobile that are best for you.

Fly from

Des Moines

Fly to

Mobile

Route

Depart

Return

Price

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Sat 10/25

5:15 pm-10:48 pm

1 stop5h 33m

Mobile

Sat 11/1

5:43 am-1:59 pm

2 stops8h 16m

$254

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Tue 9/23

6:30 pm-11:12 pm

1 stop4h 42m

Mobile

Tue 9/30

4:43 pm-10:37 pm

1 stop5h 54m

$284

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Wed 9/24

3:50 pm-11:11 pm

2 stops7h 21m

Mobile

Sun 9/28

5:52 pm-11:30 pm

1 stop5h 38m

$289

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Thu 9/18

6:15 am-11:43 am

1 stop5h 28m

Mobile

Mon 9/22

5:09 pm-10:28 pm

1 stop5h 19m

$309

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Tue 9/16

6:12 pm-11:02 pm

1 stop4h 50m

Mobile

Sat 9/20

5:22 pm-11:06 pm

1 stop5h 44m

$309

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Tue 9/16

6:15 am-11:43 am

1 stop5h 28m

Mobile

Sat 9/20

9:18 am-2:17 pm

1 stop4h 59m

$309

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Tue 9/16

6:00 am-3:58 pm

2 stops9h 58m

Mobile

Sat 9/20

4:31 pm-10:37 pm

1 stop6h 06m

$314

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Fri 10/31

5:15 pm-10:48 pm

1 stop5h 33m

$234

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Sat 10/25

3:05 pm-9:48 pm

1 stop6h 43m

$269

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Sat 10/11

6:15 am-11:43 am

1 stop5h 28m

$269

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 13 results
1
2

Best time to book a flight from Des Moines to Mobile

Have a flexible travel schedule? Discover the best time to fly to Mobile from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Mobile

What is the cheapest month to book a flight from Des Moines to Mobile?

Currently, August is the cheapest month in which you can book a flight from Des Moines to Mobile (average of $348). Flying from Des Moines to Mobile in March is currently the most expensive (average of $468). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Des Moines to Mobile?

Reviews of airlines servicing Mobile

Get insights into the airlines that provide service to Mobile. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mobile. Reviews last updated September 11, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Des Moines to Mobile. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Overall

8.0

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Overall

8.0

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,937 reviews
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Overall

8.0

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Overall

8.0

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Mobile. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Mobile?

    Delta and American Airlines can get you from Des Moines to Mobile in just under 5h 33m. Your travel time can differ by up to 1h 48m. Airlines will cover a distance of 807 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Des Moines to Mobile round-trip?

    American Airlines, at $244, was found to be the cheapest airline from Des Moines to Mobile.Alternate airlines to your destination round-trip include Delta and United Airlines. These flights start at 34% lower than the current average price 3 months from now.

  • Can I find deals for flights from Des Moines to Mobile that include hotel bookings?

    Yes. In addition to deals on Des Moines to Mobile flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Mobile?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Mobile.

  • Can I find deals for business class flights from Des Moines to Mobile?

    Yes. Cheapflights offers flight deals from Des Moines to Mobile by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Mobile?

    Currently, August is the cheapest month in which you can book a flight from Des Moines to Mobile (average of $348). Flying from Des Moines to Mobile in March is currently the most expensive (average of $468). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Mobile?

Book flights to Mobile if you plan to visit one of these locations
Pascagoula
Moss Point

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Top 3 airlines flying from Des Moines to Mobile

Discover the top 3 airlines that operate flights from Des Moines to Mobile. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$244Average$368FlexibilityNo cancel feeOn-time71%
DeltaCheapest$244Average$350FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$259Average$388FlexibilityNo cancel feeOn-time69%

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