How popular is this Colorado to Missouri flight route?

This flight path from Colorado to Missouri was viewed by 34 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

How long is the flight from Colorado to Missouri?

Frontier, United Airlines, and American Airlines can get you from Colorado to Missouri in just under 1h 42m. Your travel time can differ by up to 6h 05m. The distance between Colorado and Missouri is about 531 mi. Both multi-stop and nonstop flights can be found to your destination and back.

In terms of precipitation, rainfall in Missouri ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit Missouri when rainfall is around 2.2 in.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Can I find deals for flights from Colorado to Missouri that include hotel bookings?

Yes. In addition to deals on Colorado to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Colorado to Missouri?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Colorado to Missouri.

Can I find deals for business class flights from Colorado to Missouri?

Yes. Cheapflights offers flight deals from Colorado to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$28+ Flights from Colorado to Missouri

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Find cheap flights from Colorado to Missouri with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Colorado to Missouri

Cheapest flights from Colorado to Missouri
Explore the most affordable flight options available from Colorado to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Thu 12/2512:16 amDEN - MCI

1 stop8h 52mFrontier

Sun 1/118:23 pmMCI - DEN

Nonstop2h 04mFrontier

Deal found 12/10

$115

Wed 12/315:09 pmDEN - MCI

Nonstop1h 41mFrontier

Sun 1/48:45 pmMCI - DEN

Nonstop2h 04mFrontier

Deal found 12/10

$129

Tue 12/305:09 pmDEN - MCI

Nonstop1h 41mFrontier

Sat 1/38:45 pmMCI - DEN

Nonstop2h 04mFrontier

Deal found 12/9

$131

Tue 12/305:09 pmDEN - MCI

Nonstop1h 41mFrontier

Sun 1/48:45 pmMCI - DEN

Nonstop2h 04mFrontier

Deal found 12/10

$132

Wed 12/316:50 amDEN - STL

Nonstop2h 12mFrontier

Wed 1/77:43 pmSTL - DEN

Nonstop2h 32mFrontier

Deal found 12/11

$138

Thu 12/2512:16 amDEN - MCI

1 stop8h 52mFrontier

Sat 1/38:45 pmMCI - DEN

Nonstop2h 04mFrontier

Deal found 12/11

$153

Wed 12/316:50 amDEN - STL

Nonstop2h 12mFrontier

Fri 1/97:43 pmSTL - DEN

Nonstop2h 32mFrontier

Deal found 12/11

$153

Tue 12/305:09 pmDEN - MCI

Nonstop1h 41mFrontier

Fri 1/28:45 pmMCI - DEN

Nonstop2h 04mFrontier

Deal found 12/11

$168

Mon 12/295:09 pmDEN - MCI

Nonstop1h 41mFrontier

Sun 1/48:45 pmMCI - DEN

Nonstop2h 04mFrontier

Deal found 12/10

$169

Fri 12/265:09 pmDEN - MCI

Nonstop1h 41mFrontier

Fri 1/28:45 pmMCI - DEN

Nonstop2h 04mFrontier

Deal found 12/11

$172

Sat 12/2011:59 pmDEN - MCI

1 stop8h 18mFrontier

Sat 1/38:45 pmMCI - DEN

Nonstop2h 04mFrontier

Deal found 12/10

$173

Wed 12/316:50 amDEN - STL

Nonstop2h 12mFrontier

Mon 1/57:43 pmSTL - DEN

Nonstop2h 32mFrontier

Deal found 12/11

$175

Best flights from Colorado to Missouri
Discover carefully curated flight deals from Colorado to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 12, 2025.

Fri 2/203:24 pmDEN - MCI

Nonstop1h 42mFrontier

Mon 2/234:49 pmMCI - DEN

1 stop8h 41mFrontier

Deal found 12/11

$138

Fri 1/165:01 pmDEN - MCI

Nonstop1h 41mMultiple Airlines

Sun 1/1811:26 amMCI - DEN

2 stops21h 27mMultiple Airlines

Deal found 12/10

$153

Tue 1/278:37 pmDEN - MCI

Nonstop1h 53mUnited Airlines

Thu 1/295:45 amMCI - DEN

Nonstop2h 16mUnited Airlines

Deal found 12/10

$184

Fri 1/165:51 pmDEN - MCI

1 stop4h 36mDelta

Sun 1/186:15 amMCI - DEN

1 stop5h 16mDelta

Deal found 12/10

$197

Tue 1/68:40 amDEN - MCI

Nonstop1h 45mSouthwest

Wed 1/712:55 pmMCI - DEN

1 stop6h 00mSouthwest

Deal found 12/10

$201

Fri 1/307:50 amDEN - COU

1 stop7h 47mAmerican Airlines

Sun 2/15:07 pmCOU - DEN

1 stop6h 27mAmerican Airlines

Deal found 12/10

$218

Wed 2/411:25 amDEN - MCI

2 stops11h 08mMultiple Airlines

Fri 2/68:41 pmMCI - DEN

Nonstop2h 06mMultiple Airlines

Deal found 12/10

$157

Fri 1/96:50 amDEN - STL

Nonstop2h 12mFrontier

Sun 1/1112:37 pmSTL - DEN

1 stop16h 21mFrontier

Deal found 12/11

$165

Wed 1/72:47 pmDEN - MCI

3 stops18h 44mMultiple Airlines

Fri 1/98:31 pmMCI - DEN

Nonstop2h 04mMultiple Airlines

Deal found 12/10

$169

Tue 1/69:55 amDEN - MCI

Nonstop1h 47mUnited Airlines

Wed 1/71:42 pmMCI - DEN

Nonstop1h 59mUnited Airlines

Deal found 12/10

$191

Wed 1/79:45 pmDEN - STL

1 stop13h 27mFrontier

Sun 1/115:11 pmSTL - DEN

2 stops25h 48mFrontier

Deal found 12/11

$180

Wed 1/711:33 amDEN - MCI

1 stop4h 36mDelta

Sun 1/116:15 amMCI - DEN

1 stop5h 16mDelta

Deal found 12/11

$204

Thu 1/89:50 amDEN - MCI

Nonstop1h 47mUnited Airlines

Sun 1/115:10 pmMCI - DEN

Nonstop2h 11mUnited Airlines

Deal found 12/10

$194

Thu 1/15:00 amDEN - COU

1 stop5h 39mAmerican Airlines

Sun 1/46:05 pmCOU - DEN

1 stop4h 56mAmerican Airlines

Deal found 12/11

$218

Tue 1/272:45 pmDEN - MCI

1 stop4h 05mSouthwest

Thu 1/2912:55 pmMCI - DEN

1 stop4h 35mSouthwest

Deal found 12/10

$221

Sun 1/411:59 pmDEN - STL

1 stop7h 13mFrontier

Mon 1/510:10 pmSTL - DEN

1 stop6h 48mFrontier

Deal found 12/11

$197

Fri 1/2310:45 amDEN - COU

1 stop4h 52mAmerican Airlines

Sun 1/256:00 amCOU - DEN

1 stop5h 48mAmerican Airlines

Deal found 12/10

$218

Mon 2/166:00 amDEN - MCI

Nonstop1h 45mSouthwest

Tue 2/246:50 amMCI - DEN

Nonstop2h 00mSouthwest

Deal found 12/10

$221

Thu 1/15:45 amDEN - SGF

1 stop5h 41mDelta

Sun 1/45:03 pmSGF - DEN

1 stop8h 04mDelta

Deal found 12/10

$229

Fri 1/91:27 pmDEN - SGF

Nonstop1h 55mUnited Airlines

Mon 1/125:03 pmSGF - DEN

Nonstop2h 22mUnited Airlines

Deal found 12/9

$209

Fri 1/3012:00 pmDEN - SGF

1 stop8h 46mDelta

Tue 2/36:00 amSGF - DEN

1 stop8h 37mDelta

Deal found 12/11

$229

Fri 2/137:00 amDEN - SGF

1 stop9h 53mAmerican Airlines

Sun 2/154:48 pmSGF - DEN

1 stop7h 04mAmerican Airlines

Deal found 12/11

$229

Fri 1/161:27 pmDEN - SGF

Nonstop1h 55mUnited Airlines

Sun 1/189:00 amSGF - DEN

Nonstop2h 29mUnited Airlines

Deal found 12/9

$209

Wed 12/316:50 amDEN - STL

Nonstop2h 12mFrontier

Sat 1/37:43 pmSTL - DEN

Nonstop2h 32mFrontier

Deal found 12/11

$228

Fri 1/2312:00 pmDEN - SGF

1 stop8h 46mDelta

Mon 1/2612:01 pmSGF - DEN

1 stop8h 27mDelta

Deal found 12/9

$229

Sun 2/156:00 amCOS - MCI

1 stop6h 12mAmerican Airlines

Sat 2/215:57 pmMCI - COS

1 stop5h 11mAmerican Airlines

Deal found 12/10

$241

Fri 1/91:45 pmCOS - STL

1 stop4h 20mSouthwest

Thu 1/152:25 pmSTL - COS

1 stop8h 35mSouthwest

Deal found 12/10

$273

Fri 2/67:05 amDEN - SGF

1 stop8h 10mDelta

Sun 2/81:00 pmSGF - DEN

1 stop7h 28mDelta

Deal found 12/10

$229

Fri 12/266:50 amDEN - STL

Nonstop2h 12mFrontier

Wed 12/317:43 pmSTL - DEN

Nonstop2h 32mFrontier

Deal found 12/11

$243

Fri 1/91:51 pmCOS - MCI

2 stops8h 42mMultiple Airlines

Sun 1/118:59 amMCI - COS

1 stop25h 41mMultiple Airlines

Deal found 12/10

$295

Last-minute flights from Colorado to Missouri
Discover last-minute flight deals from Colorado to Missouri. Data last updated December 12, 2025 and is based on user searches.

Thu 12/2512:16 amDEN - MCI

1 stop8h 52mFrontier

Sun 1/118:23 pmMCI - DEN

Nonstop2h 04mFrontier

Deal found 12/10

$115

Mon 1/56:50 amDEN - STL

Nonstop2h 12mFrontier

Wed 1/77:43 pmSTL - DEN

Nonstop2h 32mFrontier

Deal found 12/11

$109

Wed 1/710:36 amDEN - STL

1 stop10h 57mFrontier

Wed 1/143:43 pmSTL - DEN

Nonstop2h 37mFrontier

Deal found 12/9

$110

Thu 1/84:47 pmDEN - MCI

Nonstop1h 39mFrontier

Thu 1/158:33 pmMCI - DEN

Nonstop2h 06mFrontier

Deal found 12/11

$104

Thu 1/810:29 pmDEN - MCI

1 stop12h 26mFrontier

Sun 1/118:23 pmMCI - DEN

Nonstop2h 04mFrontier

Deal found 12/11

$114

Sat 1/106:50 amDEN - STL

Nonstop2h 12mFrontier

Wed 1/148:32 pmSTL - DEN

1 stop16h 49mFrontier

Deal found 12/11

$106

Sat 1/106:50 amDEN - STL

Nonstop2h 12mFrontier

Mon 1/128:50 amSTL - DEN

1 stop15h 09mFrontier

Deal found 12/10

$111

Mon 1/125:01 pmDEN - MCI

Nonstop1h 40mFrontier

Thu 1/158:33 pmMCI - DEN

Nonstop2h 06mFrontier

Deal found 12/10

$107

Wed 1/1411:40 amDEN - STL

Nonstop2h 08mFrontier

Wed 1/218:22 pmSTL - DEN

2 stops16h 57mFrontier

Deal found 12/11

$112

Fri 1/235:10 pmDEN - MCI

Nonstop1h 41mFrontier

Sun 1/2511:00 amMCI - DEN

1 stop11h 45mFrontier

Deal found 12/11

$97

Fri 1/233:38 pmDEN - STL

Nonstop2h 06mFrontier

Mon 1/269:45 pmSTL - DEN

1 stop13h 47mFrontier

Deal found 12/11

$108

Sun 1/255:10 pmDEN - MCI

Nonstop1h 41mFrontier

Sun 2/111:00 amMCI - DEN

1 stop11h 45mFrontier

Deal found 12/11

$98

One-way flights from Colorado to Missouri
Search for one-way flight options from Colorado to Missouri. Find affordable one-way fares based on user searches. Data last updated December 12, 2025.

Sat 1/106:50 amDEN - STL

Nonstop2h 12mFrontier

Deal found 12/11

$28

Sat 1/1711:40 amDEN - STL

Nonstop2h 08mFrontier

Deal found 12/11

$29

Wed 2/1812:48 pmDEN - STL

Nonstop2h 05mFrontier

Deal found 12/11

$30

Mon 2/99:41 amDEN - STL

Nonstop2h 09mFrontier

Deal found 12/11

$40

Fri 1/96:50 amDEN - STL

Nonstop2h 12mFrontier

Deal found 12/10

$43

Fri 1/163:26 pmDEN - STL

Nonstop2h 06mFrontier

Deal found 12/11

$44

Fri 2/2010:01 amDEN - STL

Nonstop2h 08mFrontier

Deal found 12/10

$46

Thu 1/84:47 pmDEN - MCI

Nonstop1h 39mFrontier

Deal found 12/10

$53

Thu 1/155:07 pmDEN - MCI

Nonstop1h 41mFrontier

Deal found 12/10

$54

Mon 1/55:09 pmDEN - MCI

Nonstop1h 41mFrontier

Deal found 12/11

$55

Fri 1/305:10 pmDEN - MCI

Nonstop1h 41mFrontier

Deal found 12/11

$56

Mon 1/1212:05 amDEN - STL

1 stop29h 46mFrontier

Deal found 12/11

$57

Find flight deals from Colorado to Missouri

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$90 (Frontier)
One-way from	$28 (Kiwi.com)
Popular in	June
Cheapest in	January
Average price	$280
Good round-trip deal	$164 or less
Good one-way deal	$86 or less

Provider with most accurate pricing for Denver Intl-Lambert-St Louis flight deals.

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Provider most trusted by Cheapflights users for Denver Intl-Lambert-St Louis flights.

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From Colorado to Missouri

Search Deals

One-way flight from Colorado to Missouri

Search Deals

Highest demand for flights based on searches. 10% potential increase in price ($25 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($7 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Price to beat on a round-trip flight from Colorado to Missouri.

Search Deals

Price to beat on a one-way flight from Colorado to Missouri.

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

DenverKansas City

DEN - MCI

DENMCI

Denver Intl

Fri 2/20

3:24 pm-6:06 pm

Nonstop1h 42m

Kansas City

Mon 2/23

4:49 pm-12:30 am

1 stop8h 41m

$138

DenverKansas City

DEN - MCI

DENMCI

Denver Intl

Fri 1/16

5:01 pm-7:42 pm

Nonstop1h 41m

Kansas City

Sun 1/18

11:26 am-7:53 am

2 stops21h 27m

$153

DenverKansas City

DEN - MCI

DENMCI

Denver Intl

Wed 2/4

11:25 am-11:33 pm

2 stops11h 08m

Kansas City

Fri 2/6

8:41 pm-9:47 pm

Nonstop2h 06m

$157

DenverSt. Louis

DEN - STL

DENSTL

Denver Intl

Fri 1/9

6:50 am-10:02 am

Nonstop2h 12m

Lambert-St Louis

Sun 1/11

12:37 pm-3:58 am

1 stop16h 21m

$165

DenverKansas City

DEN - MCI

DENMCI

Denver Intl

Wed 1/7

2:47 pm-10:31 am

3 stops18h 44m

Kansas City

Fri 1/9

8:31 pm-9:35 pm

Nonstop2h 04m

$169

DenverSt. Louis

DEN - STL

DENSTL

Denver Intl

Wed 1/7

9:45 pm-12:12 pm

1 stop13h 27m

Lambert-St Louis

Sun 1/11

5:11 pm-5:59 pm

2 stops25h 48m

$180

DenverKansas City

DEN - MCI

DENMCI

Denver Intl

Tue 1/27

8:37 pm-11:30 pm

Nonstop1h 53m

Kansas City

Thu 1/29

5:45 am-7:01 am

Nonstop2h 16m

$184

DenverKansas City

DEN - MCI

DENMCI

Denver Intl

Tue 1/6

9:55 am-12:42 pm

Nonstop1h 47m

Kansas City

Wed 1/7

1:42 pm-2:41 pm

Nonstop1h 59m

$191

DenverKansas City

DEN - MCI

DENMCI

Denver Intl

Thu 1/8

9:50 am-12:37 pm

Nonstop1h 47m

Kansas City

Sun 1/11

5:10 pm-6:21 pm

Nonstop2h 11m

$194

DenverKansas City

DEN - MCI

DENMCI

Denver Intl

Fri 1/16

5:51 pm-11:27 pm

1 stop4h 36m

Kansas City

Sun 1/18

6:15 am-10:31 am

1 stop5h 16m

$197

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/11

Showing 1-10 of 60 results

...

Best time to book a flight from Colorado to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Colorado with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Colorado to Missouri

What is the cheapest month to book a flight from Colorado to Missouri?

Currently, February is the cheapest month in which you can book a flight from Colorado to Missouri (average of $37). Flying from Colorado to Missouri in July is currently the most expensive (average of $126). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CO to MO?

Unlike in the morning, when flights are generally more expensive, you can save up to 35% on flights from Colorado to Missouri by exploring options for tickets in the evening.

What is the cheapest day to fly from Colorado to Missouri?

Travelers seeking maximum savings on their Colorado to Missouri flight should consider departing on Saturday afternoons when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Colorado to Missouri

The most flights from USCO to USMO are scheduled on a Monday (12 on average). You will have fewer flight options on Sunday, which is when the least amount of flights are scheduled (6 on average).

Reviews of airlines servicing Missouri

Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Colorado to Missouri by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Southwest

7.9

Good

4,253 reviews

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Delta

7.9

Good

8,008 reviews

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

United Airlines

7.4

Good

9,095 reviews

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

American Airlines

7.2

Good

11,050 reviews

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Frontier

5.8

Fair

3,084 reviews

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

How popular is this Colorado to Missouri flight route?
This flight path from Colorado to Missouri was viewed by 34 users in the past month. Keep an eye out for changes in search interest prior to high and low season.
How long is the flight from Colorado to Missouri?
Frontier, United Airlines, and American Airlines can get you from Colorado to Missouri in just under 1h 42m. Your travel time can differ by up to 6h 05m. The distance between Colorado and Missouri is about 531 mi. Both multi-stop and nonstop flights can be found to your destination and back.
Can I find deals for flights from Colorado to Missouri that include hotel bookings?
Yes. In addition to deals on Colorado to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Colorado to Missouri?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Colorado to Missouri.
Can I find deals for business class flights from Colorado to Missouri?
Yes. Cheapflights offers flight deals from Colorado to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Colorado to Missouri?
Currently, February is the cheapest month in which you can book a flight from Colorado to Missouri (average of $37). Flying from Colorado to Missouri in July is currently the most expensive (average of $126). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 5 airlines flying from Colorado to Missouri

Airline	Cheapest	Average	Flexibility	On-time
Frontier	Cheapest$48	Average$147	FlexibilityNo cancel fee	On-time62%
United Airlines	Cheapest$121	Average$391	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$136	Average$337	FlexibilityNo cancel fee	On-time71%
Southwest	Cheapest$157	Average$346	FlexibilityNo cancel fee	On-time63%
Delta	Cheapest$218	Average$296	FlexibilityNo cancel fee	On-timeN/A

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$28+ Cheap flights from Colorado to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/10. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheap flight deals from Colorado to Missouri

Cheapest flights from Colorado to MissouriExplore the most affordable flight options available from Colorado to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Explore the most affordable flight options available from Colorado to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Find flight deals from Colorado to Missouri

Keep the following information in mind while searching for Colorado to Missouri flight deals. Data was last updated December 12, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Cheapflights Fare Finder

Use the filters below to find and compare flights from Colorado to Missouri that are best for you.

Best time to book a flight from Colorado to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Colorado with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Colorado to Missouri

What is the cheapest month to book a flight from Colorado to Missouri?

What is the cheapest time of day to fly from CO to MO?

Find hourly flight availability from Colorado to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

What is the cheapest day to fly from Colorado to Missouri?

Use this chart to determine the cheapest time to fly round-trip from Colorado to Missouri. Price data was last updated on December 16, 2024.

Weekly flight availability from Colorado to Missouri

Explore weekly flight availability from Colorado to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated December 12, 2025.

Reviews of airlines servicing Missouri

Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Colorado to Missouri by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Colorado to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How popular is this Colorado to Missouri flight route?

How long is the flight from Colorado to Missouri?

Can I find deals for flights from Colorado to Missouri that include hotel bookings?

How can I find direct flights from Colorado to Missouri?

Can I find deals for business class flights from Colorado to Missouri?

What is the cheapest month to book a flight from Colorado to Missouri?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Colorado to Missouri

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from Colorado to Missouri

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Cheapest flights from Colorado to Missouri
Explore the most affordable flight options available from Colorado to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.