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$22+ Cheap flights from Colorado to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/28. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — STL
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Colorado to Missouri

Cheapest flights from Colorado to Missouri
Explore the most affordable flight options available from Colorado to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Frontier deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/265:48 pm
DEN
-
MCI
Nonstop1h 41m
Frontier
Sat 2/288:41 pm
MCI
-
DEN
Nonstop2h 06m
Frontier
Deal found 1/28$74
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/275:07 pm
DEN
-
MCI
Nonstop1h 41m
Frontier
Wed 3/44:39 pm
MCI
-
DEN
Nonstop2h 07m
Frontier
Deal found 1/27$76
This Super.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2010:01 am
DEN
-
STL
Nonstop2h 08m
Frontier
Mon 2/231:54 pm
STL
-
DEN
Nonstop2h 36m
Frontier
Deal found 1/28$79
This Frontier deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/63:38 pm
DEN
-
STL
Nonstop2h 06m
Frontier
Sun 2/812:03 pm
STL
-
DEN
Nonstop2h 33m
Frontier
Deal found 1/27$81
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2810:48 am
DEN
-
STL
Nonstop2h 08m
Frontier
Mon 3/28:22 pm
STL
-
DEN
1 stop16h 34m
Frontier
Deal found 1/27$84
This Frontier deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/275:07 pm
DEN
-
MCI
Nonstop1h 41m
Frontier
Sun 3/11:44 pm
MCI
-
DEN
Nonstop2h 05m
Frontier
Deal found 1/28$85
This Frontier deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/146:35 am
DEN
-
STL
Nonstop2h 14m
Frontier
Sat 3/218:12 pm
STL
-
DEN
Nonstop2h 37m
Frontier
Deal found 1/28$85
This Super.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/145:05 pm
DEN
-
MCI
Nonstop1h 41m
Frontier
Sat 2/218:36 pm
MCI
-
DEN
Nonstop2h 06m
Frontier
Deal found 1/28$86
This Super.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:40 am
DEN
-
STL
Nonstop2h 08m
Frontier
Sat 4/48:16 pm
STL
-
DEN
Nonstop2h 33m
Frontier
Deal found 1/27$87
This Frontier deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2110:48 am
DEN
-
STL
Nonstop2h 08m
Frontier
Sat 2/282:51 pm
STL
-
DEN
Nonstop2h 27m
Frontier
Deal found 1/28$88
This Frontier deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/146:35 am
DEN
-
STL
Nonstop2h 14m
Frontier
Fri 3/208:12 pm
STL
-
DEN
Nonstop2h 37m
Frontier
Deal found 1/28$89
This Cheapflightsfares deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2512:48 pm
DEN
-
STL
Nonstop2h 05m
Frontier
Wed 3/48:17 pm
STL
-
DEN
1 stop12h 22m
Frontier
Deal found 1/28$92

Find flight deals from Colorado to Missouri

Keep the following information in mind while searching for Colorado to Missouri flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$74
(Frontier)

One-way from

$22
(Kiwi.com)

Popular in

June

Cheapest in

January

Average price

$181

Good round-trip deal

$133 or less

Good one-way deal

$118 or less
Provider with most accurate pricing for Denver Intl-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Denver Intl-Lambert-St Louis flights.
Search Deals
From Colorado to Missouri
Search Deals
One-way flight from Colorado to Missouri
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($21 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals
Price to beat on a round-trip flight from Colorado to Missouri.
Search Deals
Price to beat on a one-way flight from Colorado to Missouri.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Colorado to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Colorado to Missouri that are best for you.

Fly from

Colorado

Fly to

Missouri

Route

Depart

Return

Price

DenverKansas City

DEN - MCI

DENMCI

Denver Intl

Mon 3/30

5:12 pm-7:53 pm

Nonstop1h 41m

Kansas City

Fri 4/3

8:43 pm-9:45 pm

Nonstop2h 02m

$104

DenverKansas City

DEN - MCI

DENMCI

Denver Intl

Fri 2/20

2:45 pm-5:28 pm

Nonstop1h 43m

Kansas City

Sat 2/21

8:36 pm-9:42 pm

Nonstop2h 06m

$111

DenverKansas City

DEN - MCI

DENMCI

Denver Intl

Fri 3/27

5:14 pm-7:55 pm

Nonstop1h 41m

Kansas City

Mon 3/30

8:38 pm-9:44 pm

Nonstop2h 06m

$112

DenverSt. Louis

DEN - STL

DENSTL

Denver Intl

Fri 2/20

10:01 am-1:09 pm

Nonstop2h 08m

Lambert-St Louis

Mon 2/23

8:47 pm-7:54 am

1 stop12h 07m

$114

DenverKansas City

DEN - MCI

DENMCI

Denver Intl

Thu 2/26

5:48 pm-8:29 pm

Nonstop1h 41m

Kansas City

Sat 2/28

10:00 am-8:00 pm

1 stop11h 00m

$115

DenverSt. Louis

DEN - STL

DENSTL

Denver Intl

Mon 3/23

6:35 am-9:49 am

Nonstop2h 14m

Lambert-St Louis

Fri 3/27

8:12 pm-9:49 pm

Nonstop2h 37m

$118

DenverSt. Louis

DEN - STL

DENSTL

Denver Intl

Wed 2/25

8:00 pm-6:51 am

2 stops33h 51m

Lambert-St Louis

Wed 3/4

5:18 pm-6:53 pm

Nonstop2h 35m

$123

DenverKansas City

DEN - MCI

DENMCI

Denver Intl

Fri 4/3

5:11 pm-7:58 pm

Nonstop1h 47m

Kansas City

Sun 4/5

8:28 pm-9:30 pm

Nonstop2h 02m

$124

DenverKansas City

DEN - MCI

DENMCI

Denver Intl

Thu 5/14

10:45 am-1:30 pm

Nonstop1h 45m

Kansas City

Mon 5/18

2:15 pm-3:19 pm

Nonstop2h 04m

$128

DenverKansas City

DEN - MCI

DENMCI

Denver Intl

Fri 4/17

10:45 am-1:30 pm

Nonstop1h 45m

Kansas City

Mon 4/20

2:15 pm-3:19 pm

Nonstop2h 04m

$129

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 60 results
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Best time to book a flight from Colorado to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Colorado with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Colorado to Missouri

What is the cheapest month to book a flight from Colorado to Missouri?

Currently, February is the cheapest month in which you can book a flight from Colorado to Missouri (average of $37). Flying from Colorado to Missouri in July is currently the most expensive (average of $126). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CO to MO?

Find hourly flight availability from Colorado to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 29, 2026.

Unlike in the evening, when flights are generally more expensive, you can save up to 31% on flights from Colorado to Missouri by exploring options for tickets in the afternoon.

What is the cheapest day to fly from Colorado to Missouri?

Use this chart to determine the cheapest time to fly round-trip from Colorado to Missouri. Price data was last updated on January 24, 2026.

Travelers seeking maximum savings on their Colorado to Missouri flight should consider departing on Saturday afternoons when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Colorado to Missouri

Explore weekly flight availability from Colorado to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated January 29, 2026.

The most flights from USCO to USMO are scheduled on a Wednesday (12 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (5 on average).

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated January 29, 2026.
Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Colorado to Missouri by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,267 reviews

Comfort

8.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,267 reviews
Southwest
8.0
Very good
4,267 reviews

Comfort

8.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,128 reviews
Southwest
8.0
Very good
4,267 reviews

Comfort

8.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,215 reviews
Southwest
8.0
Very good
4,267 reviews

Comfort

8.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,205 reviews
Southwest
8.0
Very good
4,267 reviews

Comfort

8.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Frontier
5.7
Fair
3,056 reviews
Southwest
8.0
Very good
4,267 reviews

Comfort

8.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Colorado to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Colorado to Missouri flight route?

    This flight path from Colorado to Missouri was viewed by 30 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Colorado to Missouri?

    Frontier, American Airlines, and United Airlines can get you from Colorado to Missouri in just under 1h 41m. Your travel time can differ by up to 3h 57m. The distance between Colorado and Missouri is about 531 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Colorado to Missouri one-way?

    $29 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on Southwest and American Airlines, with prices starting from $78 and $88, respectively.

  • Can I find deals for flights from Colorado to Missouri that include hotel bookings?

    Yes. In addition to deals on Colorado to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Colorado to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Colorado to Missouri.

  • Can I find deals for business class flights from Colorado to Missouri?

    Yes. Cheapflights offers flight deals from Colorado to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Colorado to Missouri?

    Currently, February is the cheapest month in which you can book a flight from Colorado to Missouri (average of $37). Flying from Colorado to Missouri in July is currently the most expensive (average of $126). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Colorado to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Colorado to Missouri

Discover the top 5 airlines that operate flights from Colorado to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$52Average$148FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$121Average$390FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$136Average$348FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$157Average$330FlexibilityNo cancel feeOn-time63%
DeltaCheapest$218Average$293FlexibilityNo cancel feeOn-timeN/A

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