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$173+ Cheap flights from Central America to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/19. Fares are subject to change and may not be available on all flights or dates of travel.
SJO — STL
Dec 13 — Dec 201
Sat 12/13
Sat 12/20
1 adult, Economy
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Find flight deals from Central America to Missouri

Cheapest flights from Central America to Missouri
Explore the most affordable flight options available from Central America to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/222:27 pmGUA - STL
1 stop19h 13mFrontier
Tue 12/3010:48 amSTL - GUA
1 stop26h 34mFrontier
Deal found 11/12$207
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2012:20 pmGUA - STL
1 stop10h 13mMultiple Airlines
Tue 12/3010:48 amSTL - GUA
1 stop26h 34mMultiple Airlines
Deal found 11/12$229
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/183:00 pmGUA - STL
1 stop28h 42mMultiple Airlines
Tue 12/3010:48 amSTL - GUA
1 stop26h 34mMultiple Airlines
Deal found 11/12$231
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/222:27 pmGUA - STL
1 stop19h 13mMultiple Airlines
Wed 12/314:27 pmSTL - GUA
1 stop18h 58mMultiple Airlines
Deal found 11/12$247
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/222:27 pmGUA - STL
1 stop19h 13mMultiple Airlines
Sun 1/44:27 pmSTL - GUA
1 stop18h 58mMultiple Airlines
Deal found 11/12$257
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/232:55 pmGUA - MCI
1 stop19h 13mFrontier
Wed 12/3111:33 amMCI - GUA
2 stops22h 05mFrontier
Deal found 11/12$260
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/204:23 pmGUA - STL
2 stops17h 17mFrontier
Tue 12/3010:48 amSTL - GUA
1 stop26h 34mFrontier
Deal found 11/12$262
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/213:00 pmGUA - STL
1 stop7h 33mMultiple Airlines
Tue 12/3010:48 amSTL - GUA
1 stop26h 34mMultiple Airlines
Deal found 11/12$266
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/232:55 pmGUA - MCI
1 stop19h 13mMultiple Airlines
Wed 12/316:15 pmMCI - GUA
1 stop18h 19mMultiple Airlines
Deal found 11/12$267
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1612:20 pmGUA - STL
1 stop10h 13mMultiple Airlines
Tue 12/3010:48 amSTL - GUA
1 stop26h 34mMultiple Airlines
Deal found 11/12$267
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2012:20 pmGUA - STL
1 stop10h 13mMultiple Airlines
Wed 12/314:27 pmSTL - GUA
1 stop18h 58mMultiple Airlines
Deal found 11/12$268
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/203:00 pmGUA - STL
1 stop7h 33mMultiple Airlines
Sun 1/44:27 pmSTL - GUA
1 stop21h 36mMultiple Airlines
Deal found 11/12$279

Cheap flight deals from Central America to Missouri

Keep the following information in mind while searching for Central America to Missouri flight deals. Data was last updated November 13, 2025.

Round-trip from

$207
(Kiwi.com)

One-way from

$173
(Trip.com)
From Central America to Missouri
Search Deals
One-way flight from Central America to Missouri
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Central America to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from Central America to Missouri that are best for you.

Fly from

Central America

Fly to

Missouri

Route

Depart

Return

Price

Guatemala CityKansas City

GUA - MCI

GUAMCI

Guatemala City La Aurora

Tue 12/23

2:55 pm-10:08 am

1 stop19h 13m

Kansas City

Wed 12/31

6:15 pm-12:34 pm

1 stop18h 19m

$267

Guatemala CitySt. Louis

GUA - STL

GUASTL

Guatemala City La Aurora

Thu 12/18

3:00 pm-7:42 pm

1 stop28h 42m

Lambert-St Louis

Mon 1/5

4:27 pm-11:25 am

1 stop18h 58m

$267

San JoséSt. Louis

SJO - STL

SJOSTL

San José Juan Santamaria Intl

Sat 11/22

2:47 pm-2:29 pm

1 stop23h 42m

Lambert-St Louis

Fri 11/28

4:13 pm-3:20 pm

1 stop23h 07m

$285

Guatemala CityKansas City

GUA - MCI

GUAMCI

Guatemala City La Aurora

Wed 12/24

1:39 pm-5:10 pm

1 stop27h 31m

Kansas City

Wed 12/31

11:33 am-12:34 pm

2 stops25h 01m

$296

San JoséSt. Louis

SJO - STL

SJOSTL

San José Juan Santamaria Intl

Mon 2/2

7:00 am-11:39 pm

1 stop16h 39m

Lambert-St Louis

Mon 2/9

7:10 am-10:15 pm

1 stop15h 05m

$303

San JoséSt. Louis

SJO - STL

SJOSTL

San José Juan Santamaria Intl

Sat 1/31

6:30 am-10:00 pm

1 stop15h 30m

Lambert-St Louis

Mon 2/9

6:40 pm-1:15 pm

2 stops18h 35m

$303

San JoséSt. Louis

SJO - STL

SJOSTL

San José Juan Santamaria Intl

Wed 2/4

6:30 am-10:58 pm

2 stops16h 28m

Lambert-St Louis

Wed 2/11

6:00 am-6:16 pm

1 stop12h 16m

$303

San JoséSt. Louis

SJO - STL

SJOSTL

San José Juan Santamaria Intl

Tue 2/3

7:00 am-8:39 pm

1 stop13h 39m

Lambert-St Louis

Mon 2/9

9:59 am-10:15 pm

1 stop12h 16m

$303

San JoséSt. Louis

SJO - STL

SJOSTL

San José Juan Santamaria Intl

Tue 2/3

6:30 am-3:52 pm

1 stop9h 22m

Lambert-St Louis

Sun 2/8

6:40 pm-1:15 pm

2 stops18h 35m

$303

San JoséSt. Louis

SJO - STL

SJOSTL

San José Juan Santamaria Intl

Sun 2/1

7:00 am-11:39 pm

1 stop16h 39m

Lambert-St Louis

Mon 2/9

7:10 am-10:15 pm

1 stop15h 05m

$303

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/12

Showing 1-10 of 60 results
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Best time to book a flight from Central America to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Central America with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Central America to Missouri

What is the cheapest month to book a flight from Central America to Missouri?

Currently, August is the cheapest month in which you can book a flight from Central America to Missouri (average of $129). Flying from Central America to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CA to MO?

Find hourly flight availability from Central America to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 13, 2025.

A simple way to save on the total cost of your ticket is to fly from Central America to Missouri in the evening. If you’re flexible enough to do this you can expect to save up to 4% on your trip compared to booking a flight in the afternoon.

What is the cheapest day to fly from Central America to Missouri?

Use this chart to determine the cheapest time to fly round-trip from Central America to Missouri. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Central America to Missouri flight should consider departing on Tuesday evenings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated November 13, 2025.
See what other customers who have flown with Southwest, Delta, and United Airlines from Central America to Missouri have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Overall

8.0

Crew

8.6

Boarding

8.1

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Overall

8.0

Crew

8.6

Boarding

8.1

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
8,007 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Overall

8.0

Crew

8.6

Boarding

8.1

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
9,017 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Overall

8.0

Crew

8.6

Boarding

8.1

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,051 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Overall

8.0

Crew

8.6

Boarding

8.1

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Spirit Airlines
6.3
Okay
8,139 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Overall

8.0

Crew

8.6

Boarding

8.1

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Central America to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Central America to Missouri?

    A quick flight from Central America to Missouri can take about 15h 30m. Delta provides one of the quickest options available for as low as $303. Central America and Missouri are separated by a distance of 2022 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Central America to Missouri one-way?

    One-way options have recently been found by users for as low as $174 on Spirit Airlines. Other airlines that offer cheap prices include Delta from $176 and United Airlines from $176 one-way.

  • Can I find deals for flights from Central America to Missouri that include hotel bookings?

    Yes. In addition to deals on Central America to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Central America to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Central America to Missouri.

  • Can I find deals for business class flights from Central America to Missouri?

    Yes. Cheapflights offers flight deals from Central America to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Central America to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Central America to Missouri (average of $129). Flying from Central America to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Central America to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Central America to Missouri

Discover the top 5 airlines that operate flights from Central America to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$149Average$394FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$252Average$564FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$274Average$573FlexibilityNo cancel feeOn-time71%
DeltaCheapest$292Average$559FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$293Average$383FlexibilityNo cancel feeOn-time63%

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