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$228+ Cheap flights from Florence, SC (FLO) to Michigan

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/17. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — DTW
Feb 27 — Mar 61
Fri 2/27
Fri 3/6
1 adult, Economy
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Cheap flight deals from Florence to Michigan

Cheapest flights from Florence to Michigan
Explore the most affordable flight options available from Florence to Michigan. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 28, 2026.

This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/316:15 am
FLO
-
DTW
1 stop5h 08m
American Airlines
Mon 2/25:03 pm
DTW
-
FLO
1 stop5h 40m
American Airlines
Deal found 1/27$382
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/205:16 am
FLO
-
ORD
1 stop4h 49m
American Airlines
Sun 2/2210:28 am
ORD
-
FLO
1 stop6h 22m
American Airlines
Deal found 1/26$415
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/205:16 am
FLO
-
ORD
2 stops7h 49m
American Airlines
Mon 2/236:22 pm
ORD
-
FLO
1 stop4h 35m
American Airlines
Deal found 1/25$420
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/116:15 am
FLO
-
ORD
1 stop5h 27m
American Airlines
Sun 2/156:22 pm
ORD
-
FLO
1 stop4h 35m
American Airlines
Deal found 1/27$457
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/115:09 am
FLO
-
ORD
1 stop4h 55m
American Airlines
Sun 6/147:50 am
ORD
-
FLO
1 stop5h 21m
American Airlines
Deal found 1/27$466
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/265:16 am
FLO
-
ORD
1 stop4h 52m
American Airlines
Sun 3/295:00 pm
ORD
-
FLO
1 stop5h 57m
American Airlines
Deal found 1/26$486

Find flight deals from Florence to Michigan

Keep the following information in mind while searching for Florence to Michigan flight deals. Data was last updated January 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$415
(American Airlines)

One-way from

$228
(American Airlines)
Provider with most accurate pricing for Florence-Detroit (DTT) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Florence-Detroit (DTT) flights.
Search Deals
From Florence to Michigan
Search Deals
One-way flight from Florence to Michigan
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to Michigan that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
Use the filters below to find and compare flights from Florence to Michigan that are best for you.

Fly from

Florence

Fly to

Michigan

Route

Depart

Return

Price

FlorenceChicago

FLO - ORD

FLOORD

Florence

Fri 2/20

5:16 am-9:05 am

1 stop4h 49m

Chicago O'Hare Intl

Sun 2/22

10:28 am-5:50 pm

1 stop6h 22m

$415

FlorenceChicago

FLO - ORD

FLOORD

Florence

Fri 2/20

5:16 am-9:05 am

1 stop4h 49m

Chicago O'Hare Intl

Mon 2/23

5:00 pm-11:57 pm

1 stop5h 57m

$415

FlorenceChicago

FLO - ORD

FLOORD

Florence

Wed 2/11

6:15 am-10:42 am

1 stop5h 27m

Chicago O'Hare Intl

Sun 2/15

6:22 pm-11:57 pm

1 stop4h 35m

$457

FlorenceChicago

FLO - ORD

FLOORD

Florence

Thu 6/11

5:09 am-9:04 am

1 stop4h 55m

Chicago O'Hare Intl

Sun 6/14

7:50 am-2:11 pm

1 stop5h 21m

$466

FlorenceChicago

FLO - ORD

FLOORD

Florence

Thu 3/26

5:16 am-9:08 am

1 stop4h 52m

Chicago O'Hare Intl

Sun 3/29

5:00 pm-11:57 pm

1 stop5h 57m

$486

FlorenceChicago

FLO - ORD

FLOORD

Florence

Sun 5/17

5:24 am-10:14 am

1 stop5h 50m

$228

FlorenceChicago

FLO - ORD

FLOORD

Florence

Sat 4/4

5:16 am-9:08 am

1 stop4h 52m

$239

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

Best time to book a flight from Florence to Michigan

Have a flexible travel schedule? Discover the best time to fly to Michigan from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to Michigan

What is the cheapest month to book a flight from Florence, South Carolina to Michigan?

Currently, June is the cheapest month in which you can book a flight from Florence, South Carolina to Michigan (average of $71). Flying from Florence, South Carolina to Michigan in December is currently the most expensive (average of $149). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Florence to Michigan. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Florence to Michigan?

    Florence (FLO), located 2.3 mi from the city center, is the airport you fly out of when you book flights from Florence to Michigan.

  • How long is the flight from Florence, South Carolina to Michigan?

    Airlines like American Airlines fly from Florence, South Carolina to Michigan in about 4h 49m. The time it takes to get you to your destination can typically vary by up to . Florence, South Carolina and Michigan are separated by a distance of 697 mi.

  • Can I find deals for flights from Florence to Michigan that include hotel bookings?

    Yes. In addition to deals on Florence to Michigan flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to Michigan?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Michigan.

  • Can I find deals for business class flights from Florence to Michigan?

    Yes. Cheapflights offers flight deals from Florence to Michigan by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florence, South Carolina to Michigan?

    Currently, June is the cheapest month in which you can book a flight from Florence, South Carolina to Michigan (average of $71). Flying from Florence, South Carolina to Michigan in December is currently the most expensive (average of $149). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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