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$486+ Cheap flights from Columbia, MO (COU) to Mexico

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/29. Fares are subject to change and may not be available on all flights or dates of travel.
COU — MEX
May 27 — Jun 31
Wed 5/27
Wed 6/3
1 adult, Economy
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Cheap flight deals from Columbia to Mexico

Cheapest flights from Columbia to Mexico
Explore the most affordable flight options available from Columbia to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 27, 2026.

This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:17 pm
COU
-
CUN
1 stop16h 45m
American Airlines
Fri 10/212:45 pm
CUN
-
COU
1 stop9h 50m
American Airlines
Deal found 4/23$486
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/115:19 pm
COU
-
CUN
1 stop16h 44m
American Airlines
Thu 6/182:36 pm
CUN
-
COU
1 stop8h 10m
American Airlines
Deal found 4/26$552
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:32 pm
COU
-
CUN
1 stop17h 36m
American Airlines
Mon 6/17:51 am
CUN
-
COU
1 stop14h 34m
American Airlines
Deal found 4/24$553
This American Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:19 pm
COU
-
SJD
1 stop16h 43m
American Airlines
Tue 6/912:48 pm
SJD
-
COU
1 stop27h 10m
American Airlines
Deal found 4/25$598
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:32 pm
COU
-
CUN
1 stop17h 36m
American Airlines
Sun 5/3110:31 am
CUN
-
COU
1 stop12h 15m
American Airlines
Deal found 4/24$622
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/76:50 am
COU
-
CUN
1 stop13h 15m
American Airlines
Sun 6/143:45 pm
CUN
-
COU
1 stop7h 01m
American Airlines
Deal found 4/23$698
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/176:30 pm
COU
-
SJD
2 stops20h 18m
United Airlines
Wed 8/191:44 pm
SJD
-
COU
2 stops19h 11m
United Airlines
Deal found 4/27$817
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/53:16 pm
COU
-
PVR
2 stops21h 46m
United Airlines
Tue 12/83:40 pm
PVR
-
COU
2 stops19h 08m
United Airlines
Deal found 4/22$867
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:43 pm
COU
-
SJD
2 stops16h 49m
American Airlines
Sat 5/98:40 am
SJD
-
COU
2 stops12h 13m
American Airlines
Deal found 4/27$882

Find flight deals from Columbia to Mexico

Keep the following information in mind while searching for Columbia to Mexico flight deals. Data was last updated April 27, 2026.

Round-trip from

$486
(American Airlines)
From Columbia Regional to Mexico
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbia to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 27, 2026.
Use the filters below to find and compare flights from Columbia to Mexico that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ColumbiaCancún

COU - CUN

COUCUN

Columbia Regional

Tue 9/29

5:17 pm-10:02 am

1 stop16h 45m

Cancun

Fri 10/2

12:45 pm-10:35 pm

1 stop9h 50m

$486
Quickest round-trip

ColumbiaCancún

COU - CUN

COUCUN

Columbia Regional

Tue 6/9

7:16 am-1:35 pm

1 stop6h 19m

Cancun

Tue 6/16

3:45 pm-10:46 pm

1 stop7h 01m

$536

ColumbiaCancún

COU - CUN

COUCUN

Columbia Regional

Thu 6/11

5:19 pm-10:03 am

1 stop16h 44m

Cancun

Thu 6/18

2:36 pm-10:46 pm

1 stop8h 10m

$552

ColumbiaCancún

COU - CUN

COUCUN

Columbia Regional

Thu 5/28

6:32 pm-12:08 pm

1 stop17h 36m

Cancun

Mon 6/1

7:51 am-10:25 pm

1 stop14h 34m

$553

ColumbiaSan José del Cabo

COU - SJD

COUSJD

Columbia Regional

Thu 6/4

5:19 pm-8:02 am

1 stop16h 43m

San José del Cabo Los Cabos

Tue 6/9

12:48 pm-5:58 pm

1 stop27h 10m

$598

ColumbiaCancún

COU - CUN

COUCUN

Columbia Regional

Sun 6/7

6:50 am-8:05 pm

1 stop13h 15m

Cancun

Sun 6/14

3:45 pm-10:46 pm

1 stop7h 01m

$698

ColumbiaSan José del Cabo

COU - SJD

COUSJD

Columbia Regional

Mon 8/17

6:30 pm-12:48 pm

2 stops20h 18m

San José del Cabo Los Cabos

Wed 8/19

1:44 pm-10:55 am

2 stops19h 11m

$817

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/23

Sorted by cheapest first

Best time to book a flight from Columbia to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from Columbia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbia to Mexico
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Mexico

Get insights into the airlines that provide service to Mexico. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico. Reviews last updated April 27, 2026.
Peruse reviews from past customers who have flown with American Airlines from Columbia to Mexico to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,667 reviews

Boarding

7.5

Entertainment

6.9

Comfort

7.2

Food

6.4

Crew

7.9

Overall

7.1

Reviews

1 / 20
4.0
Okay

Elizabeth,Mar 2026

ORD - MIA

Staff was rude and flight attendants 2 out of 3 looked like they had just been thru a hurricane.
American Airlines
7.1
Good
11,667 reviews
American Airlines
7.1
Good
11,667 reviews

Boarding

7.5

Entertainment

6.9

Comfort

7.2

Food

6.4

Crew

7.9

Overall

7.1

Reviews

1 / 20
4.0
Okay

Elizabeth,Mar 2026

ORD - MIA

Staff was rude and flight attendants 2 out of 3 looked like they had just been thru a hurricane.

Related info for your journey

Find useful and relevant information for your journey from Columbia to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Columbia to Mexico?

    Located just 11.1 mi from the city center, Columbia Regional (COU) is the airport most travelers will use when flying to Mexico from Columbia.

  • How long is the flight from Columbia, Missouri to Mexico?

    American Airlines can get you from Columbia, Missouri to Mexico in just under 16h 45m. Your travel time can differ by up to . Airlines will cover a distance of 1268 mi.

  • What are the most popular routes from Columbia, Missouri to Mexico?

    While some choose either Columbia Regional - San José del Cabo Los Cabos or Columbia Regional - Puerto Vallarta Ordaz, Columbia Regional - Cancun is the most popular route from Columbia, Missouri to Mexico.

  • Can I find deals for flights from Columbia to Mexico that include hotel bookings?

    Yes. In addition to deals on Columbia to Mexico flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbia to Mexico?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbia to Mexico.

  • Can I find deals for business class flights from Columbia to Mexico?

    Yes. Cheapflights offers flight deals from Columbia to Mexico by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top airline flying from Columbia to Mexico

Discover the top airline that operate flights from Columbia to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$376Average$545FlexibilityNo cancel feeOn-time71%

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