HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Mesa

$79+ Cheap flights from Iowa to Mesa, AZ

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/4. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — PHX
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Iowa to Mesa with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Iowa to Mesa

Keep the following information in mind while searching for Iowa to Mesa flight deals. Data was last updated July 31, 2025.

Round-trip from

$167
(American Airlines)

One-way from

$79
(Southwest)

Popular in

March

Cheapest in

January

Average price

$323
From Iowa to Mesa
Search Deals
One-way flight from Iowa to Mesa
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($46 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2025
Search Deals

Find flight deals from Iowa to Mesa

Cheapest flights from Iowa to Mesa
Explore the most affordable flight options available from Iowa to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/308:10 pmOMA - PHX
Nonstop2h 50mSouthwest
Sun 11/28:35 amPHX - OMA
Nonstop2h 30mSouthwest
Deal found 7/30$157
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/287:30 amOMA - PHX
Nonstop2h 50mAmerican Airlines
Thu 9/49:01 amPHX - OMA
Nonstop2h 51mAmerican Airlines
Deal found 7/31$167
This Frontier deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/83:30 pmDSM - PHX
1 stop8h 25mFrontier
Wed 10/156:33 amPHX - DSM
1 stop6h 10mFrontier
Deal found 7/29$198
This Frontier deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/97:51 pmOMA - PHX
1 stop4h 43mFrontier
Tue 8/127:18 amPHX - OMA
1 stop9h 35mFrontier
Deal found 7/31$198
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/118:06 amDSM - PHX
Nonstop3h 28mAmerican Airlines
Sat 11/158:12 pmPHX - DSM
Nonstop2h 47mAmerican Airlines
Deal found 7/30$204
This Cheapflightsfares deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/278:16 pmCID - PHX
1 stop5h 13mFrontier
Fri 11/712:59 pmPHX - CID
1 stop5h 32mFrontier
Deal found 7/31$206
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/16:30 amDSM - PHX
1 stop4h 45mSouthwest
Sat 10/114:10 pmPHX - DSM
Nonstop2h 40mSouthwest
Deal found 7/30$214
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/288:25 amOMA - PHX
1 stop5h 48mDelta
Sun 8/317:05 amPHX - OMA
1 stop5h 09mDelta
Deal found 7/31$217
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/62:13 pmDSM - PHX
1 stop8h 33mDelta
Sun 10/1212:40 amPHX - DSM
1 stop7h 41mDelta
Deal found 7/28$237
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/304:59 pmMLI - PHX
1 stop7h 50mDelta
Wed 9/31:37 pmPHX - MLI
1 stop7h 11mDelta
Deal found 7/30$259
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/296:18 pmMLI - PHX
1 stop5h 53mAmerican Airlines
Sun 8/3112:24 amPHX - MLI
1 stop8h 27mAmerican Airlines
Deal found 7/30$269
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/156:53 pmSUX - PHX
1 stop5h 07mUnited Airlines
Tue 8/1911:45 amPHX - SUX
1 stop4h 28mUnited Airlines
Deal found 7/31$274

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Iowa to Mesa that are best for you.

Fly from

Iowa

Fly to

Mesa

Route

Depart

Return

Price

OmahaPhoenix

OMA - PHX

OMAPHX

Omaha Eppley Airfield

Thu 8/28

2:32 pm-3:22 pm

Nonstop2h 50m

Phoenix Sky Harbor Intl

Sun 8/31

7:10 pm-11:50 pm

Nonstop2h 40m

$167

OmahaPhoenix

OMA - PHX

OMAPHX

Omaha Eppley Airfield

Sat 9/27

3:50 pm-4:35 pm

Nonstop2h 45m

Phoenix Sky Harbor Intl

Tue 9/30

5:50 pm-10:20 pm

Nonstop2h 30m

$168

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Wed 10/15

3:30 pm-9:55 pm

1 stop8h 25m

Phoenix Sky Harbor Intl

Wed 10/22

6:33 am-2:43 pm

1 stop6h 10m

$198

OmahaPhoenix

OMA - PHX

OMAPHX

Omaha Eppley Airfield

Sat 8/9

7:51 pm-10:34 pm

1 stop4h 43m

Phoenix Sky Harbor Intl

Tue 8/12

7:18 am-6:53 pm

1 stop9h 35m

$198

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Tue 11/11

8:06 am-10:34 am

Nonstop3h 28m

Phoenix Sky Harbor Intl

Sat 11/15

8:12 pm-11:59 pm

Nonstop2h 47m

$204

Cedar RapidsPhoenix

CID - PHX

CIDPHX

Cedar Rapids

Mon 10/27

8:16 pm-11:29 pm

1 stop5h 13m

Phoenix Sky Harbor Intl

Fri 11/7

12:59 pm-7:31 pm

1 stop5h 32m

$206

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Wed 10/1

6:30 am-9:15 am

1 stop4h 45m

Phoenix Sky Harbor Intl

Sat 10/11

4:10 pm-8:50 pm

Nonstop2h 40m

$214

OmahaPhoenix

OMA - PHX

OMAPHX

Omaha Eppley Airfield

Thu 8/28

8:25 am-12:13 pm

1 stop5h 48m

Phoenix Sky Harbor Intl

Sun 8/31

7:05 am-2:14 pm

1 stop5h 09m

$217

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Wed 10/22

5:32 pm-11:04 pm

1 stop7h 32m

Phoenix Sky Harbor Intl

Tue 10/28

12:40 am-10:21 am

1 stop7h 41m

$237

MolinePhoenix

MLI - PHX

MLIPHX

Moline Quad-City

Sat 8/30

4:59 pm-10:49 pm

1 stop7h 50m

Phoenix Sky Harbor Intl

Wed 9/3

1:37 pm-10:48 pm

1 stop7h 11m

$259

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Showing 1-10 of 44 results
1
2
3
...
5

Best time to book a flight from Iowa to Mesa

Have a flexible travel schedule? Discover the best time to fly to Mesa from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Mesa

What is the cheapest month to book a flight from Iowa to Mesa?

Currently, January is the cheapest month in which you can book a flight from Iowa to Mesa (average of $258). Flying from Iowa to Mesa in March is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to MS9?

Find hourly flight availability from Iowa to Mesa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.

When flying from Iowa to Mesa, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Mesa

Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated July 31, 2025.
Get a feel of what it's like to fly with Alaska Airlines, Southwest, and Delta from Iowa to Mesa by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Crew

8.5

Food

7.1

Boarding

8.1

Overall

8.0

Entertainment

7.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Crew

8.5

Food

7.1

Boarding

8.1

Overall

8.0

Entertainment

7.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
Southwest
8.0
Very good
4,246 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Crew

8.5

Food

7.1

Boarding

8.1

Overall

8.0

Entertainment

7.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
Delta
8.0
Very good
7,981 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Crew

8.5

Food

7.1

Boarding

8.1

Overall

8.0

Entertainment

7.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
United Airlines
7.4
Good
8,900 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Crew

8.5

Food

7.1

Boarding

8.1

Overall

8.0

Entertainment

7.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Crew

8.5

Food

7.1

Boarding

8.1

Overall

8.0

Entertainment

7.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Iowa to Mesa one-way?

    To fly one-way, consider booking your trip with Southwest, which is currently one of the cheapest options available, starting at $79. American Airlines flights start at $79 while deals on Frontier start at $99 one-way.

  • What are the most popular routes from Iowa to Mesa?

    The most popular flight routes from Iowa to Mesa are Des Moines - Phoenix Sky Harbor Intl, Omaha Eppley Airfield - Phoenix Sky Harbor Intl and Cedar Rapids - Phoenix Sky Harbor Intl.

  • What are the most reliable airlines from Iowa to Mesa?

    No one likes to see their flight delayed. When booking a flight from Iowa to Mesa consider choosing Envoy Air (100%), SkyWest Airlines (94%) or Alaska Airlines (92%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Iowa to Mesa?

    Looking for the cheapest flight from Iowa to Mesa? While on average our users pay $299, our data indicates the cheapest price to be $100. The most popular route (Des Moines - Phoenix Sky Harbor Intl), is priced around $204.

  • Can I find deals for flights from Iowa to Mesa that include hotel bookings?

    Yes. In addition to deals on Iowa to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Mesa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Mesa.

  • Can I find deals for business class flights from Iowa to Mesa?

    Yes. Cheapflights offers flight deals from Iowa to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Mesa?

    Currently, January is the cheapest month in which you can book a flight from Iowa to Mesa (average of $258). Flying from Iowa to Mesa in March is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Iowa to Mesa

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Las Vegas flights
Dallas/Fort Worth to Las Vegas flights
Los Angeles to Las Vegas flights
Hobby to Las Vegas flights
O'Hare Intl to Las Vegas flights
Newark to Las Vegas flights
Denver to Las Vegas flights
Santa Ana to Las Vegas flights
LaGuardia to Las Vegas flights
Burbank to Las Vegas flights
Seattle to Las Vegas flights
Dulles Intl to Las Vegas flights
Boston to Las Vegas flights
George Bush Intcntl to Las Vegas flights
San Francisco to Las Vegas flights
Baltimore to Las Vegas flights
San Jose to Las Vegas flights
Atlanta to Las Vegas flights
O'Hare Intl to Sky Harbor Intl flights
Fort Lauderdale to Las Vegas flights
Oakland to Las Vegas flights
Reagan-National to Las Vegas flights
Minneapolis to Las Vegas flights
Austin to Las Vegas flights
Philadelphia to Las Vegas flights
Detroit to Las Vegas flights
John F Kennedy Intl to Sky Harbor Intl flights
Midway to Las Vegas flights
Love Field to Las Vegas flights
Ontario to Las Vegas flights
Orlando to Las Vegas flights
Newark to Sky Harbor Intl flights
Raleigh to Las Vegas flights
St. Louis to Las Vegas flights
San Antonio to Las Vegas flights
Tampa to Las Vegas flights
Cleveland to Las Vegas flights
Sky Harbor Intl to Las Vegas flights
Boston to Sky Harbor Intl flights
Seattle to Sky Harbor Intl flights
San Diego to Las Vegas flights
Honolulu to Las Vegas flights
Dallas/Fort Worth to Sky Harbor Intl flights
Minneapolis to Sky Harbor Intl flights
Charlotte to Las Vegas flights
Los Angeles to Sky Harbor Intl flights
Dulles Intl to Sky Harbor Intl flights
LaGuardia to Sky Harbor Intl flights
Cincinnati to Las Vegas flights
Portland to Las Vegas flights

Top 6 airlines flying from Iowa to Mesa

Discover the top 6 airlines that operate flights from Iowa to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$106Average$196FlexibilityNo cancel feeOn-time62%
Allegiant AirCheapest$121Average$229FlexibilityNo cancel feeOn-time88%
DeltaCheapest$181Average$307FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$198Average$330FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$204Average$378FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$216Average$416FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.