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Mesa

$55+ Cheap flights from Iowa to Mesa, AZ

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/15. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — PHX
Dec 3 — Dec 101
Wed 12/3
Wed 12/10
1 adult, Economy
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Cheap flight deals from Iowa to Mesa

Keep the following information in mind while searching for Iowa to Mesa flight deals. Data was last updated November 3, 2025.

Round-trip from

$130
(Frontier)

One-way from

$55
(Priceline)

Popular in

March

Cheapest in

January

Average price

$323
From Iowa to Mesa
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One-way flight from Iowa to Mesa
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Highest demand for flights based on searches. 11% potential increase in price ($41 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Iowa to Mesa

Cheapest flights from Iowa to Mesa
Explore the most affordable flight options available from Iowa to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 3, 2025.

This Frontier deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/177:16 pmCID - PHX
1 stop6h 13mFrontier
Thu 11/207:00 amPHX - CID
1 stop11h 46mFrontier
Deal found 11/3$130
This Expedia deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/168:26 pmCID - PHX
1 stop12h 58mFrontier
Thu 11/207:00 amPHX - CID
1 stop11h 46mFrontier
Deal found 11/1$138
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/86:20 pmDSM - PHX
Nonstop3h 20mAmerican Airlines
Mon 12/158:00 pmPHX - DSM
Nonstop2h 52mAmerican Airlines
Deal found 11/2$177
This Mytrip deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/102:32 pmDSM - PHX
1 stop8h 12mFrontier
Sun 12/710:26 pmPHX - DSM
1 stop19h 37mFrontier
Deal found 11/2$183
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/57:58 pmDSM - PHX
2 stops13h 57mFrontier
Fri 12/129:16 amPHX - DSM
1 stop8h 47mFrontier
Deal found 11/1$198
This Frontier deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/102:32 pmDSM - PHX
1 stop6h 01mFrontier
Thu 11/137:30 amPHX - DSM
1 stop5h 26mFrontier
Deal found 11/2$210
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/47:00 amDSM - PHX
2 stops12h 31mMultiple Airlines
Sun 12/710:26 pmPHX - DSM
1 stop19h 37mMultiple Airlines
Deal found 11/2$212
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/35:21 amDSM - PHX
Nonstop3h 20mAmerican Airlines
Sat 12/68:12 pmPHX - DSM
Nonstop2h 47mAmerican Airlines
Deal found 11/1$214
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/267:02 pmCID - PHX
1 stop18h 03mMultiple Airlines
Wed 12/34:32 pmPHX - CID
1 stop25h 42mMultiple Airlines
Deal found 11/3$216
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/34:59 pmDSM - PHX
1 stop8h 05mDelta
Sat 12/611:55 pmPHX - DSM
1 stop8h 45mDelta
Deal found 11/2$217
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/26:10 pmOMA - PHX
Nonstop2h 50mSouthwest
Sat 12/612:30 pmPHX - OMA
1 stop7h 35mSouthwest
Deal found 11/1$219
This Booking.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/102:32 pmDSM - PHX
1 stop22h 43mFrontier
Wed 11/125:16 pmPHX - DSM
1 stop19h 40mFrontier
Deal found 11/2$222

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from Iowa to Mesa that are best for you.

Fly from

Iowa

Fly to

Mesa

Route

Depart

Return

Price

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Wed 12/3

4:59 pm-12:04 am

1 stop8h 05m

Phoenix Sky Harbor Intl

Thu 12/4

12:59 am-10:21 am

1 stop8h 22m

$217

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Sat 1/17

12:25 pm-7:05 pm

1 stop7h 40m

Phoenix Sky Harbor Intl

Fri 1/23

12:59 am-10:14 am

1 stop8h 15m

$217

Cedar RapidsPhoenix

CID - PHX

CIDPHX

Cedar Rapids

Sat 1/17

2:55 pm-9:02 pm

1 stop7h 07m

Phoenix Sky Harbor Intl

Wed 1/21

1:55 pm-9:51 pm

1 stop6h 56m

$217

Cedar RapidsPhoenix

CID - PHX

CIDPHX

Cedar Rapids

Wed 1/21

5:35 am-12:23 pm

1 stop7h 48m

Phoenix Sky Harbor Intl

Wed 1/28

7:10 am-3:35 pm

1 stop7h 25m

$217

OmahaPhoenix

OMA - PHX

OMAPHX

Omaha Eppley Airfield

Fri 12/5

6:25 am-10:55 am

1 stop5h 30m

Phoenix Sky Harbor Intl

Tue 12/9

6:40 pm-10:10 pm

Nonstop2h 30m

$223

Cedar RapidsPhoenix

CID - PHX

CIDPHX

Cedar Rapids

Tue 1/27

12:11 pm-11:48 pm

2 stops12h 37m

Phoenix Sky Harbor Intl

Sat 1/31

8:00 am-10:45 pm

2 stops13h 45m

$227

Cedar RapidsPhoenix

CID - PHX

CIDPHX

Cedar Rapids

Sat 2/21

12:25 pm-11:48 pm

2 stops12h 23m

Phoenix Sky Harbor Intl

Wed 2/25

12:45 pm-10:45 pm

2 stops9h 00m

$227

OmahaPhoenix

OMA - PHX

OMAPHX

Omaha Eppley Airfield

Sun 1/11

6:35 am-11:41 am

1 stop6h 06m

Phoenix Sky Harbor Intl

Tue 1/27

11:53 pm-10:13 am

1 stop9h 20m

$235

Cedar RapidsPhoenix

CID - PHX

CIDPHX

Cedar Rapids

Tue 1/27

12:11 pm-6:21 pm

1 stop7h 10m

Phoenix Sky Harbor Intl

Wed 2/11

1:55 pm-9:51 pm

1 stop6h 56m

$238

OmahaPhoenix

OMA - PHX

OMAPHX

Omaha Eppley Airfield

Tue 12/2

6:10 pm-8:00 pm

Nonstop2h 50m

Phoenix Sky Harbor Intl

Sat 12/6

5:10 am-11:55 am

1 stop5h 45m

$244

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/2

Showing 1-10 of 60 results
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Best time to book a flight from Iowa to Mesa

Have a flexible travel schedule? Discover the best time to fly to Mesa from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Mesa

What is the cheapest month to book a flight from Iowa to Mesa?

Currently, September is the cheapest month in which you can book a flight from Iowa to Mesa (average of $102). Flying from Iowa to Mesa in February is currently the most expensive (average of $154). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to MS9?

Find hourly flight availability from Iowa to Mesa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 3, 2025.

When flying from Iowa to Mesa, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 29% versus a flight at noon.

What is the cheapest day to fly from Iowa to Mesa?

Use this chart to determine the cheapest time to fly round-trip from Iowa to Mesa. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Iowa to Mesa flight should consider departing on Tuesday afternoons when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Iowa to Mesa?

    Airlines like Delta, Southwest, and United Airlines fly from Iowa to Mesa in about 5h 30m. The time it takes to get you to your destination can typically vary by up to 2h 35m. The distance between Iowa and Mesa is about 1035 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Iowa to Mesa?

    The most popular flight routes from Iowa to Mesa are Des Moines - Phoenix Sky Harbor Intl, Omaha Eppley Airfield - Phoenix Sky Harbor Intl and Cedar Rapids - Phoenix Sky Harbor Intl.

  • What are the most reliable airlines from Iowa to Mesa?

    No one likes to see their flight delayed. When booking a flight from Iowa to Mesa consider choosing Alaska Airlines (82%), American Airlines (79%) or SkyWest Airlines (78%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Iowa to Mesa?

    Looking for the cheapest flight from Iowa to Mesa? While on average our users pay $287, our data indicates the cheapest price to be $98. The most popular route (Des Moines - Phoenix Sky Harbor Intl), is priced around $164.

  • Can I find deals for flights from Iowa to Mesa that include hotel bookings?

    Yes. In addition to deals on Iowa to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Mesa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Mesa.

  • Can I find deals for business class flights from Iowa to Mesa?

    Yes. Cheapflights offers flight deals from Iowa to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Mesa?

    Currently, September is the cheapest month in which you can book a flight from Iowa to Mesa (average of $102). Flying from Iowa to Mesa in February is currently the most expensive (average of $154). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Iowa to Mesa

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Iowa to Mesa

Discover the top 6 airlines that operate flights from Iowa to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$108Average$216FlexibilityNo cancel feeOn-time62%
Allegiant AirCheapest$119Average$230FlexibilityNo cancel feeOn-time88%
DeltaCheapest$181Average$297FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$191Average$335FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$192Average$488FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$234Average$365FlexibilityNo cancel feeOn-time69%

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