Cheap flights from Mesa, AZ to Des Moines (DSM) from $64

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight to Des Moines departing on 4/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PHX — DSM
Mar 5 — Mar 121

The best prices from Mesa to Des Moines are usually found in February or January, booked 74 days in advance, depart on a Tuesday or Saturday and return on a Saturday

Cheap flight deals from Mesa to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Mesa (MS9) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 29, 2024.

Popular in

June

Cheapest in

February

Round-trip from

$323

One-way from

$189
High demand for flights, 13% potential price rise
Best time to find cheap flights, 14% potential price drop
From Mesa to Des Moines
One-way flight from Mesa to Des Moines

How far in advance should I book a flight from Mesa to Des Moines?

To save up to 137% on this flight, we recommend booking at least 52 days prior to travel. The price may fluctuate and will likely increase closer to your departure date. Users on Cheapflights have found tickets from Mesa to Des Moines from $350 1-2 weeks out and tickets from $636 for flights departing within the next 72 hours.

What is the cheapest month to fly from Mesa to Des Moines?

Flights from Mesa to Des Moines lean towards being more expensive in June. Prices are generally better when you fly from Mesa to Des Moines in February, with the cheapest ticket starting at $211.

When is the cheapest time to fly from Mesa to Des Moines (MS9 - DSM)?

When flying from Mesa to Des Moines, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Cheap Frontier flights from Mesa to Des Moines

Explore cheap flight options specifically provided by Frontier for the route between Mesa and Des Moines. Find affordable fares and compare prices with other airlines to secure the best deal for your journey. Over the last 7 days, Cheapflights users made 3,314,962 searches. Data last updated February 29, 2024.
Find some of the cheapest Frontier flights traveling from Mesa to Des Moines. Make sure to double check the flight details before booking.
Wed 4/105:50 amPHX - DSM
1 stop6h 35mFrontier
Sat 4/133:25 pmDSM - PHX
1 stop8h 54mFrontier
Deal found 2/28$89
Tue 4/169:30 pmPHX - DSM
1 stop14h 55mFrontier
Sat 4/203:25 pmDSM - PHX
1 stop8h 54mFrontier
Deal found 2/29$90
Wed 4/105:50 amPHX - DSM
1 stop6h 35mFrontier
Sat 4/133:25 pmDSM - PHX
1 stop8h 54mFrontier
Deal found 2/28$103
Thu 5/167:28 pmPHX - DSM
1 stop22h 53mFrontier
Sat 5/189:15 pmDSM - PHX
1 stop5h 08mFrontier
Deal found 2/27$110
Tue 3/199:44 pmPHX - DSM
1 stop11h 27mFrontier
Tue 3/262:10 pmDSM - PHX
1 stop27h 28mFrontier
Deal found 2/28$129
Thu 4/257:11 pmPHX - DSM
1 stop19h 06mFrontier
Sat 4/273:13 pmDSM - PHX
1 stop17h 04mFrontier
Deal found 2/28$167
Sun 5/197:28 pmPHX - DSM
1 stop23h 04mFrontier
Wed 5/229:15 pmDSM - PHX
1 stop5h 08mFrontier
Deal found 2/29$169
Fri 4/125:50 amPHX - DSM
1 stop8h 27mFrontier
Mon 4/154:06 pmDSM - PHX
1 stop7h 55mFrontier
Deal found 2/27$189
Tue 3/199:44 pmPHX - DSM
1 stop11h 27mFrontier
Thu 3/212:10 pmDSM - PHX
1 stop27h 14mFrontier
Deal found 2/27$224

Cheap United Airlines flights from Mesa to Des Moines

Explore cheap flight options specifically provided by United Airlines for the route between Mesa and Des Moines. Find affordable fares and compare prices with other airlines to secure the best deal for your journey. Over the last 7 days, Cheapflights users made 3,314,962 searches. Data last updated February 29, 2024.
Some of the best deals we've found on United Airlines flights traveling from Mesa to Des Moines. If these deals don't fit your criteria, make sure to check back soon as new deals are always added.
Fri 4/56:30 pmPHX - DSM
1 stop24h 07mUnited Airlines
Tue 4/91:30 pmDSM - PHX
1 stop9h 13mUnited Airlines
Deal found 2/28$328
Fri 4/56:30 pmPHX - DSM
1 stop24h 07mUnited Airlines
Mon 4/156:37 pmDSM - PHX
2 stops16h 06mUnited Airlines
Deal found 2/28$347
Fri 4/56:30 pmPHX - DSM
1 stop24h 07mUnited Airlines
Tue 4/96:00 amDSM - PHX
2 stops16h 35mUnited Airlines
Deal found 2/28$348
Wed 4/36:30 pmPHX - DSM
1 stop24h 07mUnited Airlines
Wed 4/108:00 amDSM - PHX
2 stops15h 58mUnited Airlines
Deal found 2/28$361
Fri 4/126:30 pmPHX - DSM
2 stops18h 03mUnited Airlines
Mon 4/156:37 pmDSM - PHX
2 stops18h 07mUnited Airlines
Deal found 2/27$366
Mon 4/1512:35 amPHX - DSM
1 stop19h 09mUnited Airlines
Sat 4/201:30 pmDSM - PHX
1 stop9h 13mUnited Airlines
Deal found 2/28$382
Mon 6/36:37 pmPHX - DSM
1 stop27h 00mUnited Airlines
Mon 6/105:14 pmDSM - PHX
1 stop6h 31mUnited Airlines
Deal found 2/28$388
Thu 6/134:40 pmPHX - DSM
1 stop4h 57mUnited Airlines
Sun 6/166:00 amDSM - PHX
1 stop4h 40mUnited Airlines
Deal found 2/29$463
Wed 3/61:57 pmPHX - DSM
1 stop6h 35mUnited Airlines
Sun 3/105:10 pmDSM - PHX
1 stop7h 05mUnited Airlines
Deal found 2/28$491

Cheap Mesa to Des Moines flights in February & March 2024

Find cheap flight options from Mesa to Des Moines specifically for the months of February and March 2024. Explore affordable fares based on user searches. Over the last 7 days, Cheapflights users made 3,314,962 searches. Prices were last updated on February 29, 2024.
Listed are some of the best fares we've found on flights departing from Mesa to Des Moines in 2024. More deals are always being added, so be sure to check back regularly.
Tue 3/199:44 pmPHX - DSM
1 stop11h 27mFrontier
Tue 3/262:10 pmDSM - PHX
1 stop27h 28mFrontier
Deal found 2/28$129
Tue 3/199:44 pmPHX - DSM
1 stop11h 27mFrontier
Thu 3/212:10 pmDSM - PHX
1 stop27h 14mFrontier
Deal found 2/27$224
Wed 3/68:40 pmPHX - DSM
1 stop25h 31mMultiple Airlines
Wed 3/1312:01 pmDSM - PHX
1 stop13h 24mMultiple Airlines
Deal found 2/28$253
Tue 3/196:00 amPHX - DSM
1 stop27h 11mFrontier
Thu 3/212:10 pmDSM - PHX
2 stops28h 12mFrontier
Deal found 2/27$272
Fri 3/2912:52 pmPHX - DSM
Nonstop2h 42mAmerican Airlines
Fri 4/56:19 pmDSM - PHX
Nonstop3h 07mAmerican Airlines
Deal found 2/28$277
Fri 3/297:27 pmPHX - DSM
Nonstop2h 42mAmerican Airlines
Fri 4/126:03 pmDSM - PHX
1 stop6h 46mAmerican Airlines
Deal found 2/29$286
Fri 3/297:27 pmPHX - DSM
Nonstop2h 42mAmerican Airlines
Fri 4/126:19 pmDSM - PHX
Nonstop3h 07mAmerican Airlines
Deal found 2/29$317
Fri 3/291:13 pmPHX - DSM
1 stop6h 16mMultiple Airlines
Mon 4/294:08 pmDSM - PHX
2 stops23h 08mMultiple Airlines
Deal found 2/28$321
Fri 3/291:13 pmPHX - DSM
1 stop6h 16mMultiple Airlines
Mon 4/297:00 amDSM - PHX
1 stop26h 58mMultiple Airlines
Deal found 2/28$324

Mesa to Des Moines 2024 flight deals

Discover exclusive flight deals for travel between Mesa and Des Moines in 2024. Find excellent offers based on user searches. Over the last 7 days, Cheapflights users made 3,314,962 searches. Data last updated February 29, 2024.
Listed are some of the best fares we've found on flights departing from Mesa to Des Moines in 2024. More deals are always being added, so be sure to check back regularly.
Wed 4/105:50 amPHX - DSM
1 stop6h 35mFrontier
Sat 4/133:25 pmDSM - PHX
1 stop8h 54mFrontier
Deal found 2/28$89
Wed 4/105:50 amPHX - DSM
1 stop6h 35mFrontier
Sat 4/133:25 pmDSM - PHX
1 stop8h 54mFrontier
Deal found 2/28$103
Thu 5/167:28 pmPHX - DSM
1 stop22h 53mFrontier
Sat 5/189:15 pmDSM - PHX
1 stop5h 08mFrontier
Deal found 2/27$110
Tue 3/199:44 pmPHX - DSM
1 stop11h 27mFrontier
Tue 3/262:10 pmDSM - PHX
1 stop27h 28mFrontier
Deal found 2/28$129
Thu 4/257:11 pmPHX - DSM
1 stop19h 06mFrontier
Sat 4/273:13 pmDSM - PHX
1 stop17h 04mFrontier
Deal found 2/28$167
Sun 5/197:28 pmPHX - DSM
1 stop23h 04mFrontier
Wed 5/229:15 pmDSM - PHX
1 stop5h 08mFrontier
Deal found 2/29$169
Fri 4/125:50 amPHX - DSM
1 stop8h 27mFrontier
Mon 4/154:06 pmDSM - PHX
1 stop7h 55mFrontier
Deal found 2/27$189
Tue 3/199:44 pmPHX - DSM
1 stop11h 27mFrontier
Thu 3/212:10 pmDSM - PHX
1 stop27h 14mFrontier
Deal found 2/27$224
Wed 3/68:40 pmPHX - DSM
1 stop25h 31mMultiple Airlines
Wed 3/1312:01 pmDSM - PHX
1 stop13h 24mMultiple Airlines
Deal found 2/28$253

Non-stop flights to Des Moines from Mesa

Discover non-stop flight options from Mesa to Des Moines. Find direct flights with no layovers, providing a convenient travel experience. Explore non-stop flight options based on user searches, and compare prices and availability for your desired travel dates. Over the last 7 days, Cheapflights users made 3,314,962 searches. Data last updated February 29, 2024.
For a quicker trip, book one of these direct flights from Mesa to Des Moines. Users seeking other options on flights from Mesa to Des Moines should update the search form at the top of the page.
Wed 4/2412:35 pmPHX - DSM
Nonstop2h 49mAmerican Airlines
Tue 4/302:40 pmDSM - PHX
Nonstop3h 19mAmerican Airlines
Deal found 2/29$263
Fri 4/512:35 pmPHX - DSM
Nonstop2h 49mAmerican Airlines
Tue 4/92:40 pmDSM - PHX
Nonstop3h 12mAmerican Airlines
Deal found 2/29$270
Fri 4/1212:35 pmPHX - DSM
Nonstop2h 49mAmerican Airlines
Mon 4/156:19 pmDSM - PHX
Nonstop3h 07mAmerican Airlines
Deal found 2/29$276
Fri 3/2912:52 pmPHX - DSM
Nonstop2h 42mAmerican Airlines
Fri 4/56:19 pmDSM - PHX
Nonstop3h 07mAmerican Airlines
Deal found 2/28$277
Tue 4/2312:35 pmPHX - DSM
Nonstop2h 49mAmerican Airlines
Tue 4/308:00 amDSM - PHX
Nonstop3h 09mAmerican Airlines
Deal found 2/28$347
Wed 6/267:06 pmPHX - DSM
Nonstop2h 51mAmerican Airlines
Thu 7/45:40 amDSM - PHX
Nonstop3h 05mAmerican Airlines
Deal found 2/27$351
Wed 4/312:52 pmPHX - DSM
Nonstop2h 42mAmerican Airlines
Wed 4/102:40 pmDSM - PHX
Nonstop3h 19mAmerican Airlines
Deal found 2/28$355
Sun 5/267:12 pmPHX - DSM
Nonstop2h 43mAmerican Airlines
Thu 5/305:34 amDSM - PHX
Nonstop3h 10mAmerican Airlines
Deal found 2/28$361
Thu 3/218:54 amPHX - DSM
Nonstop3h 02mAmerican Airlines
Sat 3/236:24 pmDSM - PHX
Nonstop3h 17mAmerican Airlines
Deal found 2/28$367

Mesa to Des Moines flights leaving soon

Find last-minute flight options from Mesa to Des Moines for spontaneous travel. Discover available flights and compare prices based on user searches. Secure great deals and offers for spontaneous trips with quick booking options. Over the last 7 days, Cheapflights users made 3,314,962 searches. Data last updated February 29, 2024.
Book one of these great deals on flights from Mesa to Des Moines. Tip: verify your flight details before completing your reservation.
Wed 3/68:40 pmPHX - DSM
1 stop25h 31mMultiple Airlines
Wed 3/1312:01 pmDSM - PHX
1 stop13h 24mMultiple Airlines
Deal found 2/28$253
Wed 3/69:55 pmPHX - DSM
2 stops24h 46mMultiple Airlines
Wed 3/1312:01 pmDSM - PHX
1 stop13h 24mMultiple Airlines
Deal found 2/28$327
Wed 3/69:55 pmPHX - DSM
3 stops24h 16mMultiple Airlines
Wed 3/1312:01 pmDSM - PHX
1 stop13h 24mMultiple Airlines
Deal found 2/28$343
Sat 3/99:40 pmPHX - DSM
2 stops16h 05mMultiple Airlines
Mon 3/187:00 amDSM - PHX
1 stop11h 49mMultiple Airlines
Deal found 2/27$372
Sat 3/910:49 pmPHX - DSM
1 stop22h 22mMultiple Airlines
Mon 3/187:00 amDSM - PHX
1 stop7h 23mMultiple Airlines
Deal found 2/27$375
Wed 3/61:58 pmPHX - DSM
Nonstop2h 35mAmerican Airlines
Wed 3/136:24 pmDSM - PHX
Nonstop3h 17mAmerican Airlines
Deal found 2/28$400
Wed 3/61:58 pmPHX - DSM
Nonstop2h 35mAmerican Airlines
Wed 3/135:00 amDSM - PHX
1 stop6h 11mAmerican Airlines
Deal found 2/28$409
Wed 3/69:55 pmPHX - DSM
3 stops24h 16mMultiple Airlines
Wed 3/1310:00 amDSM - PHX
2 stops12h 49mMultiple Airlines
Deal found 2/28$455
Sat 3/912:20 pmPHX - DSM
2 stops26h 16mMultiple Airlines
Mon 3/185:04 pmDSM - PHX
3 stops20h 31mMultiple Airlines
Deal found 2/27$458

One-way flights to Des Moines from Mesa

Search for one-way flight options from Mesa to Des Moines. Find affordable one-way fares based on user searches. Compare prices and availability to plan your one-way journey according to your preferred dates and budget. Over the last 7 days, Cheapflights users made 3,314,962 searches. Data last updated February 29, 2024.
Take a look at some of the one-way flights we've detected from Mesa to Des Moines. Those seeking round-trip flights from Mesa to Des Moines should utilize the search form at the the top of the page.
Tue 4/29:44 pmPHX - DSM
1 stop11h 27mFrontier
Deal found 2/28$64
Tue 3/269:44 pmPHX - DSM
1 stop11h 27mFrontier
Deal found 2/29$66
Tue 4/24:00 pmPHX - DSM
1 stop17h 11mFrontier
Deal found 2/28$69
Fri 4/125:50 amPHX - DSM
1 stop8h 27mFrontier
Deal found 2/28$74
Fri 5/177:01 amPHX - DSM
1 stop11h 20mFrontier
Deal found 2/28$80
Tue 3/199:44 pmPHX - DSM
1 stop11h 27mFrontier
Deal found 2/27$94
Tue 4/25:31 pmPHX - DSM
2 stops15h 40mFrontier
Deal found 2/28$117
Tue 3/267:27 pmPHX - DSM
Nonstop2h 42mAmerican Airlines
Deal found 2/29$132
Thu 3/289:44 pmPHX - DSM
1 stop12h 03mFrontier
Deal found 2/28$137

Find flights from Mesa to Des Moines within your budget

Customize your flight search to find flights from Mesa to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 3,314,962 searches. Data last updated February 29, 2024.

Fly from

Any airport

Fly to

Any airport

Budget

$89 - $329

Route

Depart

Return

Price

Phoenix Sky Harbor IntlDes Moines

PHX - DSM

PHXDSM

Phoenix Sky Harbor Intl

Wed 4/10

1 stop6h 35m

Des Moines

Sat 4/13

1 stop8h 54m

$89

Phoenix Sky Harbor IntlDes Moines

PHX - DSM

PHXDSM

Phoenix Sky Harbor Intl

Tue 4/16

1 stop14h 55m

Des Moines

Sat 4/20

1 stop8h 54m

$90

Phoenix Sky Harbor IntlDes Moines

PHX - DSM

PHXDSM

Phoenix Sky Harbor Intl

Wed 4/10

1 stop6h 35m

Des Moines

Sat 4/13

1 stop8h 54m

$103

Phoenix Sky Harbor IntlDes Moines

PHX - DSM

PHXDSM

Phoenix Sky Harbor Intl

Thu 5/16

1 stop22h 53m

Des Moines

Sat 5/18

1 stop5h 08m

$110

Phoenix Sky Harbor IntlDes Moines

PHX - DSM

PHXDSM

Phoenix Sky Harbor Intl

Tue 3/19

1 stop11h 27m

Des Moines

Tue 3/26

1 stop27h 28m

$129

Phoenix Sky Harbor IntlDes Moines

PHX - DSM

PHXDSM

Phoenix Sky Harbor Intl

Wed 4/24

Nonstop2h 49m

Des Moines

Tue 4/30

Nonstop3h 19m

$263

Phoenix Sky Harbor IntlDes Moines

PHX - DSM

PHXDSM

Phoenix Sky Harbor Intl

Fri 3/29

1 stop6h 16m

Des Moines

Mon 4/29

2 stops23h 08m

$321

Phoenix Sky Harbor IntlDes Moines

PHX - DSM

PHXDSM

Phoenix Sky Harbor Intl

Fri 4/5

1 stop24h 07m

Des Moines

Tue 4/9

1 stop9h 13m

$328

Phoenix Sky Harbor IntlDes Moines

PHX - DSM

PHXDSM

Phoenix Sky Harbor Intl

Fri 4/12

2 stops16h 55m

Des Moines

Mon 4/15

1 stop6h 47m

$329

Flights are sorted by cheapest first

Deals found on 2/28

When is the best time to book a flight from Mesa to Des Moines?

Use this chart to determine the optimal time to book a round-trip flight from Mesa to Des Moines. Price data was last updated on January 28, 2024.
The price you pay for your flight from Mesa to Des Moines may vary depending on when you book. For the best chance of a lower fare, look to book 74 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Search Deals

When is the cheapest time to fly from Mesa to Des Moines?

Use this chart to determine the cheapest time to fly round-trip from Mesa to Des Moines. Price data was last updated on February 25, 2024.
Morning
Noon
Afternoon
Evening
All times are departure.
Travelers seeking maximum savings on their Mesa to Des Moines flight should consider departing on Friday afternoons when fares are most often at their lowest. Thursday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Search Deals

Average price of flights to Des Moines by month

Plan your trip from Mesa to Des Moines by taking into account the cheapest months to travel. The average price of a one-way flight from Mesa to Des Moines is currently $93 while a round-trip flight costs $196. Price data was last updated on February 25, 2024.

Currently, January is the cheapest month in which you can book a flight from Mesa to Des Moines (average of $323). Flying from Mesa to Des Moines in June is currently the most expensive (average of $454). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

January

$323

February

$364

March

$389

April

$379

May

$408

June

$454

July

$433

August

$385

September

$347

October

$370

November

$384

December

$370

Temperature and rainfall in Des Moines by month

Plan your trip to Des Moines by taking into account the average temperature and rainfall totals by month.

DSM

Temperature

23 - 77 °F

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated February 29, 2024.
Read through reviews of airlines operating flights from Mesa to Des Moines, such as Frontier, United Airlines and Southwest. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.2
Very good
6,486 reviews

Comfort

8.1

Entertainment

7.9

Overall

8.2

Food

7.4

Crew

8.8

Boarding

8.4

Reviews

1 / 10

No tray tables for food or drink not convenient nor comfortable

Southwest
8.2
Very good
6,486 reviews
Southwest
8.2
Very good
6,486 reviews

Comfort

8.1

Entertainment

7.9

Overall

8.2

Food

7.4

Crew

8.8

Boarding

8.4

Reviews

1 / 10

No tray tables for food or drink not convenient nor comfortable

8.1
Very good
11,818 reviews
Southwest
8.2
Very good
6,486 reviews

Comfort

8.1

Entertainment

7.9

Overall

8.2

Food

7.4

Crew

8.8

Boarding

8.4

Reviews

1 / 10

No tray tables for food or drink not convenient nor comfortable

7.6
Good
3,142 reviews
Southwest
8.2
Very good
6,486 reviews

Comfort

8.1

Entertainment

7.9

Overall

8.2

Food

7.4

Crew

8.8

Boarding

8.4

Reviews

1 / 10

No tray tables for food or drink not convenient nor comfortable

7.4
Good
11,794 reviews
Southwest
8.2
Very good
6,486 reviews

Comfort

8.1

Entertainment

7.9

Overall

8.2

Food

7.4

Crew

8.8

Boarding

8.4

Reviews

1 / 10

No tray tables for food or drink not convenient nor comfortable

7.3
Good
15,571 reviews
Southwest
8.2
Very good
6,486 reviews

Comfort

8.1

Entertainment

7.9

Overall

8.2

Food

7.4

Crew

8.8

Boarding

8.4

Reviews

1 / 10

No tray tables for food or drink not convenient nor comfortable

Related info for your journey

Find useful and relevant information for your journey from Mesa to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Des Moines from Mesa?

For a flight from Mesa to Des Moines, you will be flying into Des Moines. Des Moines (DSM) is just 3.6 mi from the center of the city. Des Moines is the only Des Moines airport and it handles 4 inbound flights from Mesa per day. 4 airlines have flights to Des Moines from Mesa on a regular basis.

Can I find flights from Mesa to Des Moines for under $100 on Cheapflights?

Yes, there are multiple flights from Mesa to Des Moines for under $100. The cheapest flight booked recently is on Frontier for just $89, but on average you can expect to pay $216.

Are there nonstop flights from Mesa to Des Moines for under $300 on Cheapflights?

Cheapflights has at least 20 direct flights from Mesa to Des Moines under $300. A good price for a nonstop flight from Mesa to Des Moines is less than $365.

Are there last-minute flights available from Mesa to Des Moines for under $300?

There are currently 20+ open flights from Mesa to Des Moines within the next 7 days for less than $300.

What days are nonstop flights available from Mesa to Des Moines?

Days when nonstop flights are available for this flight are: Friday.

How many flights depart from Mesa to Des Moines on average per day?

On average, you can expect to see 2 flights from Mesa to Des Moines a day.
Afternoon (Noon - 6pm) - 100% of flight departures

How long is the flight from Mesa to Des Moines?

Frontier, American Airlines, and United Airlines can get you from Mesa to Des Moines in just under 2h 49m. Your travel time can differ by up to 21h 18m. Mesa and Des Moines are separated by a distance of 1154 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

What are the cheapest airlines to fly from Mesa to Des Moines one-way?

One-way options have recently been found by users for as low as $64 on Frontier. Other airlines that offer cheap prices include American Airlines from $132 and Delta from $148 one-way.

What are the most popular airlines that fly from Mesa to Des Moines?

What are the cheapest flights from Mesa to Des Moines?

While on average a flight from Mesa to Des Moines is generally $325, our data shows the cheapest flight currently is $144. When looking at the most popular route, (Phoenix Sky Harbor Intl - Des Moines), you can expect to pay $201 for that flight.

What does PHX to DSM mean?

PHX and DSM are unique codes to identify airports used in the aviation industry. They are defined by IATA (International Air Transport Association) and are commonly called IATA codes. PHX to DSM refers to a flight route from Phoenix Sky Harbor Intl Airport to Des Moines Airport. Phoenix-Mesa Gateway Airport (AZA), Prescott Airport (PRC) are some additional IATA codes for airports related to your trip.

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 4 airlines flying from Mesa to Des Moines

Discover the top 4 airlines that operate flights from Mesa to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 3,314,962 searches. Data last updated February 29, 2024.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$73Average$228FlexibilityNo cancel feeOn-time88%
Search Allegiant Air flights
FrontierCheapest$155Average$225FlexibilityNo cancel feeOn-time62%
Search Frontier flights
American AirlinesCheapest$252Average$418FlexibilityNo cancel feeOn-time71%
Search American Airlines flights
United AirlinesCheapest$285Average$396FlexibilityNo cancel feeOn-time69%
Search United Airlines flights