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$92+ Cheap flights from Des Moines (DSM) to Mesa, AZ

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/29. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — PHX
May 4 — May 111
Sun 5/4
Sun 5/11
1 adult, Economy
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Cheapflights Tip: The best prices from Des Moines to Mesa are usually found in January or November, booked 50 days in advance, depart on a Tuesday or Wednesday and return on a Tuesday

Cheap flight deals from Des Moines to Mesa

Keep the following information in mind while searching for Des Moines to Mesa flight deals. Data was last updated April 29, 2025.

Round-trip from

$208
(Frontier)

One-way from

$92
(Mytrip)

Popular in

March

Cheapest in

January

Average price

$380
From Des Moines to Mesa
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One-way flight from Des Moines to Mesa
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Highest demand for flights based on searches. 10% potential increase in price ($42 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Des Moines to Mesa

Cheapest flights from Des Moines to Mesa
Explore the most affordable flight options available from Des Moines to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.

This Frontier deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/77:30 pmDSM - PHX
1 stop5h 17mFrontier
Mon 5/125:50 amPHX - DSM
1 stop10h 40mFrontier
Deal found 4/28$208
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/245:30 amDSM - PHX
Nonstop3h 06mAmerican Airlines
Wed 5/288:35 amPHX - DSM
Nonstop2h 45mAmerican Airlines
Deal found 4/28$209
This Mytrip deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2910:21 pmDSM - PHX
1 stop11h 52mMultiple Airlines
Sun 6/19:19 amPHX - DSM
2 stops35h 14mMultiple Airlines
Deal found 4/29$234
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/136:07 amDSM - PHX
1 stop9h 39mDelta
Fri 6/2010:54 amPHX - DSM
1 stop7h 43mDelta
Deal found 4/29$237
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/245:20 pmDSM - PHX
1 stop5h 01mUnited Airlines
Sat 5/315:15 amPHX - DSM
2 stops9h 03mUnited Airlines
Deal found 4/29$282
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/205:40 amDSM - PHX
2 stops7h 20mSouthwest
Sat 5/245:45 pmPHX - DSM
Nonstop2h 40mSouthwest
Deal found 4/29$293

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
Use the filters below to find and compare flights from Des Moines to Mesa that are best for you.

Fly from

Des Moines

Fly to

Mesa

Route

Depart

Return

Price

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Wed 5/7

7:30 pm-10:47 pm

1 stop5h 17m

Phoenix Sky Harbor Intl

Mon 5/12

5:50 am-6:30 pm

1 stop10h 40m

$208

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Sat 5/24

5:30 am-6:36 am

Nonstop3h 06m

Phoenix Sky Harbor Intl

Wed 5/28

8:35 am-1:20 pm

Nonstop2h 45m

$209

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Thu 5/29

10:21 pm-8:13 am

1 stop11h 52m

Phoenix Sky Harbor Intl

Sun 6/1

9:19 am-10:33 pm

2 stops35h 14m

$234

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Fri 6/13

6:07 am-1:46 pm

1 stop9h 39m

Phoenix Sky Harbor Intl

Fri 6/20

10:54 am-8:37 pm

1 stop7h 43m

$237

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Sat 5/24

5:20 pm-8:21 pm

1 stop5h 01m

Phoenix Sky Harbor Intl

Sat 5/31

5:15 am-4:18 pm

2 stops9h 03m

$282

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Tue 5/20

5:40 am-11:00 am

2 stops7h 20m

Phoenix Sky Harbor Intl

Sat 5/24

5:45 pm-10:25 pm

Nonstop2h 40m

$293

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Thu 5/29

10:21 pm-8:13 am

1 stop11h 52m

$92

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Fri 5/30

2:44 pm-3:52 pm

Nonstop3h 08m

$99

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Fri 5/30

8:20 pm-11:41 pm

1 stop5h 21m

$108

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Tue 6/3

5:35 am-12:15 pm

1 stop8h 40m

$119

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/28

Showing 1-10 of 12 results
1
2

Best time to book a flight from Des Moines to Mesa

Have a flexible travel schedule? Discover the best time to fly to Mesa from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Mesa

How far ahead should I book a flight from Des Moines to Mesa?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Mesa. Price data was last updated on April 25, 2025.

To ensure you get the cheapest price possible for a flight from Des Moines to Mesa, you should look to book at least 50 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Des Moines to Mesa?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Mesa (average of $258). Flying from Des Moines to Mesa in March is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to MS9?

Find hourly flight availability from Des Moines to Mesa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 29, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Mesa as you normally would.

What is the cheapest day to fly from Des Moines to Mesa?

Use this chart to determine the cheapest time to fly round-trip from Des Moines to Mesa. Price data was last updated on March 30, 2025.

Travelers seeking maximum savings on their Des Moines to Mesa flight should consider departing on Wednesday evenings when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in Mesa by month

Plan your trip to Mesa by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Mesa ranges from 0.0 - 1.1 inches per month. July is typically the wettest month, when rainfall can reach 1.1 in. June is typically the driest time to visit Mesa when rainfall is around 0.0 in.

Temperature in Mesa by month

Plan your trip to Mesa by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Mesa, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 95.0 F. Travelers looking to avoid the cold should look outside of December, when temperatures are typically at their lowest (around 55.4 F).

Reviews of airlines servicing Mesa

Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated April 29, 2025.
Read reviews from past customers who have flown Southwest, Delta and United Airlines from Des Moines to Mesa. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,295 reviews

Entertainment

7.6

Boarding

8.2

Food

7.1

Crew

8.6

Overall

8.0

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Southwest
8.0
Very good
4,295 reviews
Southwest
8.0
Very good
4,295 reviews

Entertainment

7.6

Boarding

8.2

Food

7.1

Crew

8.6

Overall

8.0

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Delta
8.0
Very good
7,936 reviews
Southwest
8.0
Very good
4,295 reviews

Entertainment

7.6

Boarding

8.2

Food

7.1

Crew

8.6

Overall

8.0

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
United Airlines
7.4
Good
8,696 reviews
Southwest
8.0
Very good
4,295 reviews

Entertainment

7.6

Boarding

8.2

Food

7.1

Crew

8.6

Overall

8.0

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,295 reviews

Entertainment

7.6

Boarding

8.2

Food

7.1

Crew

8.6

Overall

8.0

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Frontier
6.0
Okay
3,287 reviews
Southwest
8.0
Very good
4,295 reviews

Entertainment

7.6

Boarding

8.2

Food

7.1

Crew

8.6

Overall

8.0

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Mesa?

    Located just 3.6 mi from the city center, Des Moines is the airport most travelers will use when flying to Mesa from Des Moines. Booking flights from Des Moines (DSM) to Mesa should be relatively easy as there are 3 daily outbound flights to Mesa from 6 different airlines.

  • What are the cheapest airlines to fly from Des Moines to Mesa one-way?

    $100 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on Frontier and Delta, with prices starting from $108 and $119, respectively.

  • What are the most reliable airlines from Des Moines to Mesa?

    Before booking your flight to Mesa from Des Moines, check out the most reliable airlines to get you to your destination on time: Envoy Air (92%), Alaska Airlines (91%), SkyWest Airlines( 91%).

  • What are the cheapest flights from Des Moines to Mesa?

    Looking at all options, your cheapest flight can be booked for $119. While the most popular route (Des Moines - Phoenix Sky Harbor Intl) can be booked for $219 on average our data indicates $543 when flying from Des Moines to Mesa.

  • Can I find deals for flights from Des Moines to Mesa that include hotel bookings?

    Yes. In addition to deals on Des Moines to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Mesa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Mesa.

  • Can I find deals for business class flights from Des Moines to Mesa?

    Yes. Cheapflights offers flight deals from Des Moines to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Mesa?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Mesa (average of $258). Flying from Des Moines to Mesa in March is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 6 airlines flying from Des Moines to Mesa

Discover the top 6 airlines that operate flights from Des Moines to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$106Average$249FlexibilityNo cancel feeOn-time62%
Allegiant AirCheapest$119Average$234FlexibilityNo cancel feeOn-time88%
SouthwestCheapest$199Average$328FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$217Average$360FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$236Average$418FlexibilityNo cancel feeOn-time69%
DeltaCheapest$256Average$473FlexibilityNo cancel feeOn-timeN/A

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