$85+ Cheap flights from Des Moines (DSM) to Mesa, AZ
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/11. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — PHX
May 13 — May 201
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Mesa with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Des Moines to Mesa are usually found in October or August, booked 53 days in advance, depart on a Wednesday or Saturday and return on a Tuesday
Cheap flight deals from Des Moines to Mesa
Cheapest
Best
Last-minute
One-way
Cheapest flights from Des Moines to MesaExplore the most affordable flight options available from Des Moines to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 13, 2026.
Explore the most affordable flight options available from Des Moines to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 13, 2026.
This CheapOair deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/152:16 pm
DSM
- PHX
1 stop22h 00m
Frontier
Tue 6/234:53 pm
PHX
- DSM
1 stop18h 38m
Frontier
Deal found 4/9![Frontier logo]()
$241
This Expedia deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/172:04 pm
DSM
- PHX
1 stop11h 38m
Frontier
Mon 4/206:50 am
PHX
- DSM
1 stop4h 19m
Frontier
Deal found 4/8![Frontier logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/110:14 pm
DSM
- PHX
1 stop15h 36m
Multiple Airlines
Mon 5/115:15 am
PHX
- DSM
2 stops15h 42m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$244
This Frontier deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/272:04 pm
DSM
- PHX
1 stop8h 12m
Frontier
Mon 5/48:52 am
PHX
- DSM
1 stop8h 46m
Frontier
Deal found 4/10![Frontier logo]()
$245
This Frontier deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/292:16 pm
DSM
- PHX
1 stop8h 54m
Frontier
Mon 6/15:15 am
PHX
- DSM
1 stop6h 16m
Frontier
Deal found 4/8![Frontier logo]()
$246
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/12:16 pm
DSM
- PHX
1 stop21h 49m
Multiple Airlines
Wed 6/310:27 pm
PHX
- DSM
1 stop19h 44m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/19:17 pm
DSM
- PHX
1 stop16h 06m
Multiple Airlines
Thu 6/49:15 am
PHX
- DSM
1 stop24h 07m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:23 pm
DSM
- PHX
2 stops16h 42m
Multiple Airlines
Wed 5/610:27 pm
PHX
- DSM
1 stop17h 34m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$254
This Frontier deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/172:04 pm
DSM
- PHX
1 stop11h 38m
Frontier
Fri 4/246:50 am
PHX
- DSM
1 stop4h 19m
Frontier
Deal found 4/11![Frontier logo]()
$256
This Trip.com deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/152:16 pm
DSM
- PHX
1 stop8h 54m
Frontier
Fri 6/55:15 am
PHX
- DSM
1 stop6h 16m
Frontier
Deal found 4/10![Frontier logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:23 pm
DSM
- PHX
2 stops28h 32m
Frontier
Fri 5/295:15 am
PHX
- DSM
1 stop6h 16m
Frontier
Deal found 4/12![Frontier logo]()
$261
Best flights from Des Moines to MesaDiscover carefully curated flight deals from Des Moines to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 13, 2026.
Discover carefully curated flight deals from Des Moines to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 13, 2026.
This Delta deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/197:01 am
DSM
- PHX
1 stop7h 33m
Delta
Mon 5/2512:59 am
PHX
- DSM
1 stop7h 17m
Delta
Deal found 4/9![Delta logo]()
$349
This Southwest deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/302:00 pm
DSM
- PHX
2 stops6h 15m
Southwest
Tue 6/211:35 am
PHX
- DSM
2 stops7h 40m
Southwest
Deal found 4/12![Southwest logo]()
$359
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/298:04 am
DSM
- PHX
2 stops10h 50m
United Airlines
Wed 5/61:50 pm
PHX
- DSM
2 stops7h 54m
United Airlines
Deal found 4/8![United Airlines logo]()
$450
This Delta deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/255:28 pm
DSM
- PHX
1 stop8h 01m
Delta
Sat 5/306:05 am
PHX
- DSM
1 stop7h 39m
Delta
Deal found 4/9![Delta logo]()
$365
This Delta deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2312:29 pm
DSM
- PHX
1 stop7h 14m
Delta
Sun 5/2412:59 am
PHX
- DSM
1 stop7h 17m
Delta
Deal found 4/8![Delta logo]()
$365
This Southwest deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/172:25 pm
DSM
- PHX
1 stop4h 50m
Southwest
Mon 9/211:30 pm
PHX
- DSM
1 stop6h 40m
Southwest
Deal found 4/12![Southwest logo]()
$419
This United Airlines deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/86:50 pm
DSM
- PHX
1 stop6h 32m
United Airlines
Tue 6/166:54 pm
PHX
- DSM
2 stops13h 33m
United Airlines
Deal found 4/12![United Airlines logo]()
$460
This Southwest deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/63:15 pm
DSM
- PHX
2 stops7h 35m
Southwest
Thu 5/712:20 pm
PHX
- DSM
2 stops7h 35m
Southwest
Deal found 4/12![Southwest logo]()
$419
This Southwest deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/227:10 pm
DSM
- PHX
1 stop5h 00m
Southwest
Mon 5/2512:25 pm
PHX
- DSM
2 stops8h 40m
Southwest
Deal found 4/10![Southwest logo]()
$424
This Southwest deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/111:30 pm
DSM
- PHX
2 stops8h 45m
Southwest
Mon 6/1511:05 am
PHX
- DSM
2 stops9h 15m
Southwest
Deal found 4/11![Southwest logo]()
$440
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/231:30 pm
DSM
- PHX
2 stops8h 45m
Southwest
Mon 7/2711:20 am
PHX
- DSM
2 stops9h 00m
Southwest
Deal found 4/9![Southwest logo]()
$440
Last-minute flights from Des Moines to MesaDiscover last-minute flight deals from Des Moines to Mesa. Data last updated April 13, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Mesa. Data last updated April 13, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/172:04 pm
DSM
- PHX
1 stop11h 38m
Frontier
Mon 4/206:50 am
PHX
- DSM
1 stop4h 19m
Frontier
Deal found 4/8![Frontier logo]()
$242
This Frontier deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/172:04 pm
DSM
- PHX
1 stop11h 38m
Frontier
Fri 4/246:50 am
PHX
- DSM
1 stop4h 19m
Frontier
Deal found 4/11![Frontier logo]()
$256
This Super.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/172:04 pm
DSM
- PHX
1 stop11h 38m
Frontier
Sun 4/198:52 am
PHX
- DSM
1 stop26h 17m
Frontier
Deal found 4/8![Frontier logo]()
$323
This Kiwi.com deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1710:14 pm
DSM
- PHX
2 stops20h 31m
Multiple Airlines
Thu 4/309:24 pm
PHX
- DSM
1 stop13h 45m
Multiple Airlines
Deal found 4/10![Multiple Airlines logo]()
$348
This Kiwi.com deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/192:59 pm
DSM
- PHX
2 stops18h 37m
Multiple Airlines
Thu 4/309:24 pm
PHX
- DSM
1 stop13h 45m
Multiple Airlines
Deal found 4/10![Multiple Airlines logo]()
$325
This Frontier deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/202:04 pm
DSM
- PHX
1 stop8h 12m
Frontier
Fri 4/246:50 am
PHX
- DSM
1 stop4h 19m
Frontier
Deal found 4/9![Frontier logo]()
$276
This Kiwi.com deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/208:15 pm
DSM
- PHX
1 stop18h 40m
Multiple Airlines
Thu 4/309:24 pm
PHX
- DSM
1 stop13h 45m
Multiple Airlines
Deal found 4/10![Multiple Airlines logo]()
$311
One-way flights from Des Moines to MesaSearch for one-way flight options from Des Moines to Mesa. Find affordable one-way fares based on user searches. Data last updated April 13, 2026.
Search for one-way flight options from Des Moines to Mesa. Find affordable one-way fares based on user searches. Data last updated April 13, 2026.
This Super.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/112:16 pm
DSM
- PHX
1 stop27h 07m
Frontier
Deal found 4/8![Frontier logo]()
$85
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/89:56 pm
DSM
- PHX
1 stop27h 04m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$89
This Trip.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/272:16 pm
DSM
- PHX
1 stop19h 28m
Frontier
Deal found 4/12![Frontier logo]()
$94
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1110:00 am
DSM
- PHX
1 stop9h 52m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$104
This Frontier deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/82:16 pm
DSM
- PHX
1 stop11h 13m
Frontier
Deal found 4/8![Frontier logo]()
$106
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:15 pm
DSM
- PHX
1 stop17h 08m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$107
This Frontier deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/82:16 pm
DSM
- PHX
1 stop11h 18m
Frontier
Deal found 4/8![Frontier logo]()
$111
This Expedia deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/102:16 pm
DSM
- PHX
1 stop19h 29m
Frontier
Deal found 4/11![Frontier logo]()
$112
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/110:14 pm
DSM
- PHX
1 stop15h 36m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$114
This Super.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/242:04 pm
DSM
- PHX
1 stop8h 12m
Frontier
Deal found 4/12![Frontier logo]()
$119
Find flight deals from Des Moines to Mesa
Keep the following information in mind while searching for Des Moines to Mesa flight deals. Data was last updated April 13, 2026.
Round-trip from | $241 (CheapOair) |
|---|---|
One-way from | $85 (Super.com) |
Popular in | April |
Cheapest in | October |
Average price | $403 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 13, 2026.
Use the filters below to find and compare flights from Des Moines to Mesa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesPhoenix
DSM - PHX
DSMPHX
Des Moines
Tue 5/19
7:01 am-12:34 pm
1 stop7h 33m
Phoenix Sky Harbor Intl
Mon 5/25
12:59 am-10:16 am
1 stop7h 17m
$349
Des MoinesPhoenix
DSM - PHX
DSMPHX
Des Moines
Sat 5/30
2:00 pm-6:15 pm
2 stops6h 15m
Phoenix Sky Harbor Intl
Tue 6/2
11:35 am-9:15 pm
2 stops7h 40m
$359
Des MoinesPhoenix
DSM - PHX
DSMPHX
Des Moines
Mon 5/25
5:28 pm-11:29 pm
1 stop8h 01m
Phoenix Sky Harbor Intl
Sat 5/30
6:05 am-3:44 pm
1 stop7h 39m
$365
Des MoinesPhoenix
DSM - PHX
DSMPHX
Des Moines
Sat 5/23
12:29 pm-5:43 pm
1 stop7h 14m
Phoenix Sky Harbor Intl
Sun 5/24
12:59 am-10:16 am
1 stop7h 17m
$365
Quickest round-trip
Des MoinesPhoenix
DSM - PHX
DSMPHX
Des Moines
Thu 9/17
2:25 pm-5:15 pm
1 stop4h 50m
Phoenix Sky Harbor Intl
Mon 9/21
1:30 pm-10:10 pm
1 stop6h 40m
$419
Des MoinesPhoenix
DSM - PHX
DSMPHX
Des Moines
Wed 5/6
3:15 pm-8:50 pm
2 stops7h 35m
Phoenix Sky Harbor Intl
Thu 5/7
12:20 pm-9:55 pm
2 stops7h 35m
$419
Des MoinesPhoenix
DSM - PHX
DSMPHX
Des Moines
Fri 5/22
7:10 pm-10:10 pm
1 stop5h 00m
Phoenix Sky Harbor Intl
Mon 5/25
12:25 pm-11:05 pm
2 stops8h 40m
$424
Des MoinesPhoenix
DSM - PHX
DSMPHX
Des Moines
Thu 6/11
1:30 pm-8:15 pm
2 stops8h 45m
Phoenix Sky Harbor Intl
Mon 6/15
11:05 am-10:20 pm
2 stops9h 15m
$440
Des MoinesPhoenix
DSM - PHX
DSMPHX
Des Moines
Thu 7/23
1:30 pm-8:15 pm
2 stops8h 45m
Phoenix Sky Harbor Intl
Mon 7/27
11:20 am-10:20 pm
2 stops9h 00m
$440
Des MoinesPhoenix
DSM - PHX
DSMPHX
Des Moines
Wed 4/29
8:04 am-4:54 pm
2 stops10h 50m
Phoenix Sky Harbor Intl
Wed 5/6
1:50 pm-11:44 pm
2 stops7h 54m
$450
Showing 1-10 of 20 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Mesa
Have a flexible travel schedule? Discover the best time to fly to Mesa from Des Moines with our price prediction graph.
DSM-PHX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Mesa
DSM-MS9
DSM-PHX
How far ahead should I book a flight from Des Moines to Mesa?
Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Mesa. Price data was last updated on April 10, 2026.
To ensure you get the cheapest price possible for a flight from Des Moines to Mesa, you should look to book at least 53 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Des Moines to Mesa?
Currently, December is the cheapest month in which you can book a flight from Des Moines to Mesa (average of $54). Flying from Des Moines to Mesa in February is currently the most expensive (average of $207). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DSM to MS9?
Find hourly flight availability from Des Moines to Mesa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 13, 2026.
One of the essential ways to save on airfare from Des Moines to Mesa is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight at noon could potentially save you up to 40% on airfare.
Weekly flight availability from Des Moines to Mesa
Explore weekly flight availability from Des Moines to Mesa. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated April 13, 2026.
The most flights from DSM to MS9 are scheduled on a Monday (7 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (4 on average).
How much does it cost to fly round-trip from Des Moines to Mesa?
Reviews of airlines servicing Mesa
Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated April 13, 2026.
Read reviews from past customers who have flown Southwest,United Airlines, andAllegiant Air from Des Moines to Mesa. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Des Moines and Mesa flights
Browse other Des Moines and Mesa flight options. Last updated on April 13, 2026.
Other flights from Des Moines
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Des Moines to Mesa flights
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Top 7 airlines flying from Des Moines to Mesa
Discover the top 7 airlines that operate flights from Des Moines to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$122 | Average$242 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$152 | Average$287 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$160 | Average$274 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$187 | Average$356 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$195 | Average$344 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$212 | Average$390 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$219 | Average$328 | FlexibilityNo cancel fee | On-time62% |