$79+ Cheap flights from Des Moines (DSM) to Mesa, AZ
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/24. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — PHX
Jul 25 — Aug 11
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Mesa with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Des Moines to Mesa are usually found in October or August, booked 53 days in advance, depart on a Wednesday or Saturday and return on a Wednesday
Cheap flight deals from Des Moines to Mesa
Cheapest
Best
Last-minute
One-way
Cheapest flights from Des Moines to MesaExplore the most affordable flight options available from Des Moines to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 25, 2026.
Explore the most affordable flight options available from Des Moines to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/219:31 pm
DSM
- PHX
1 stop15h 18m
Multiple Airlines
Tue 10/610:55 pm
PHX
- DSM
1 stop12h 57m
Multiple Airlines
Deal found 6/23![Multiple Airlines logo]()
$178
This Kiwi.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1710:06 pm
DSM
- PHX
1 stop16h 53m
Multiple Airlines
Thu 8/209:03 am
PHX
- DSM
1 stop9h 57m
Multiple Airlines
Deal found 6/22![Multiple Airlines logo]()
$192
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1710:06 pm
DSM
- PHX
1 stop27h 18m
Multiple Airlines
Sat 8/2210:09 pm
PHX
- DSM
1 stop20h 51m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$200
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1710:01 pm
DSM
- PHX
1 stop15h 26m
Multiple Airlines
Tue 7/219:58 pm
PHX
- DSM
1 stop13h 01m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1010:06 pm
DSM
- PHX
1 stop26h 59m
Multiple Airlines
Mon 8/249:03 am
PHX
- DSM
1 stop8h 45m
Multiple Airlines
Deal found 6/25![Multiple Airlines logo]()
$210
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/169:44 pm
DSM
- PHX
1 stop15h 43m
Multiple Airlines
Wed 8/1910:09 pm
PHX
- DSM
1 stop20h 51m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$217
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3110:01 pm
DSM
- PHX
1 stop15h 26m
Multiple Airlines
Wed 8/59:58 pm
PHX
- DSM
1 stop20h 56m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$218
Best flights from Des Moines to MesaDiscover carefully curated flight deals from Des Moines to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 25, 2026.
Discover carefully curated flight deals from Des Moines to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 25, 2026.
This Southwest deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/162:40 pm
DSM
- PHX
1 stop6h 20m
Southwest
Tue 9/226:20 am
PHX
- DSM
1 stop5h 35m
Southwest
Deal found 6/20![Southwest logo]()
$341
This Delta deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1910:59 am
DSM
- PHX
1 stop6h 59m
Delta
Sat 10/37:05 am
PHX
- DSM
1 stop5h 01m
Delta
Deal found 6/20![Delta logo]()
$341
This United Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/85:21 pm
DSM
- PHX
1 stop5h 03m
United Airlines
Sat 9/126:09 am
PHX
- DSM
1 stop6h 05m
United Airlines
Deal found 6/23![United Airlines logo]()
$431
This Southwest deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/232:40 pm
DSM
- PHX
1 stop6h 20m
Southwest
Wed 10/712:00 pm
PHX
- DSM
2 stops7h 50m
Southwest
Deal found 6/23![Southwest logo]()
$346
This Southwest deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:10 am
DSM
- PHX
1 stop8h 25m
Southwest
Wed 9/911:35 am
PHX
- DSM
2 stops8h 20m
Southwest
Deal found 6/23![Southwest logo]()
$346
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:00 am
DSM
- PHX
1 stop9h 50m
Delta
Fri 9/1111:05 pm
PHX
- DSM
1 stop8h 28m
Delta
Deal found 6/23![Delta logo]()
$418
This United Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/183:20 pm
DSM
- PHX
1 stop9h 01m
United Airlines
Wed 8/199:00 am
PHX
- DSM
1 stop6h 28m
United Airlines
Deal found 6/23![United Airlines logo]()
$431
This United Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/261:35 pm
DSM
- PHX
2 stops9h 02m
United Airlines
Sat 8/296:09 am
PHX
- DSM
1 stop6h 05m
United Airlines
Deal found 6/21![United Airlines logo]()
$436
This Southwest deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1912:10 pm
DSM
- PHX
2 stops7h 35m
Southwest
Sat 10/311:00 am
PHX
- DSM
2 stops7h 35m
Southwest
Deal found 6/20![Southwest logo]()
$397
This United Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/151:21 pm
DSM
- PHX
2 stops9h 03m
United Airlines
Sat 8/229:23 am
PHX
- DSM
2 stops10h 00m
United Airlines
Deal found 6/20![United Airlines logo]()
$441
This Southwest deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/153:45 pm
DSM
- PHX
2 stops9h 10m
Southwest
Wed 7/2210:40 am
PHX
- DSM
2 stops9h 05m
Southwest
Deal found 6/20![Southwest logo]()
$413
Last-minute flights from Des Moines to MesaDiscover last-minute flight deals from Des Moines to Mesa. Data last updated June 25, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Mesa. Data last updated June 25, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/152:19 pm
DSM
- PHX
1 stop19h 21m
Frontier
Mon 7/206:40 am
PHX
- DSM
1 stop4h 54m
Frontier
Deal found 6/24![Frontier logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1710:01 pm
DSM
- PHX
1 stop15h 26m
Multiple Airlines
Tue 7/219:58 pm
PHX
- DSM
1 stop13h 01m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1710:01 pm
DSM
- PHX
1 stop15h 26m
Multiple Airlines
Thu 7/232:16 pm
PHX
- DSM
2 stops28h 55m
Multiple Airlines
Deal found 6/24![Multiple Airlines logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1710:01 pm
DSM
- PHX
1 stop15h 26m
Multiple Airlines
Wed 7/229:58 pm
PHX
- DSM
1 stop20h 45m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$243
This Expedia deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/222:19 pm
DSM
- PHX
1 stop21h 52m
Frontier
Fri 7/246:40 am
PHX
- DSM
1 stop4h 54m
Frontier
Deal found 6/22![Frontier logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3110:01 pm
DSM
- PHX
1 stop15h 26m
Multiple Airlines
Wed 8/59:58 pm
PHX
- DSM
1 stop20h 56m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$218
One-way flights from Des Moines to MesaSearch for one-way flight options from Des Moines to Mesa. Find affordable one-way fares based on user searches. Data last updated June 25, 2026.
Search for one-way flight options from Des Moines to Mesa. Find affordable one-way fares based on user searches. Data last updated June 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:38 pm
DSM
- PHX
1 stop18h 21m
Multiple Airlines
Deal found 6/24![Multiple Airlines logo]()
$79
This Trip.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2010:01 pm
DSM
- PHX
1 stop16h 58m
Multiple Airlines
Deal found 6/24![Multiple Airlines logo]()
$82
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1710:06 pm
DSM
- PHX
1 stop27h 18m
Multiple Airlines
Deal found 6/23![Multiple Airlines logo]()
$83
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/219:31 pm
DSM
- PHX
1 stop15h 18m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$85
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/79:21 pm
DSM
- PHX
1 stop16h 06m
Multiple Airlines
Deal found 6/24![Multiple Airlines logo]()
$89
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3110:01 pm
DSM
- PHX
1 stop15h 26m
Multiple Airlines
Deal found 6/24![Multiple Airlines logo]()
$96
This Trip.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2710:01 pm
DSM
- PHX
1 stop27h 04m
Multiple Airlines
Deal found 6/23![Multiple Airlines logo]()
$97
This Trip.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1310:01 pm
DSM
- PHX
1 stop16h 58m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$104
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1710:01 pm
DSM
- PHX
1 stop15h 26m
Multiple Airlines
Deal found 6/23![Multiple Airlines logo]()
$107
This Super.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/52:19 pm
DSM
- PHX
1 stop19h 21m
Frontier
Deal found 6/23![Frontier logo]()
$110
Find flight deals from Des Moines to Mesa
Keep the following information in mind while searching for Des Moines to Mesa flight deals. Data was last updated June 25, 2026.
Round-trip from | $178 (Kiwi.com) |
|---|---|
One-way from | $79 (Kiwi.com) |
Popular in | July |
Cheapest in | October |
Average price | $393 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 25, 2026.
Use the filters below to find and compare flights from Des Moines to Mesa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesPhoenix
DSM - PHX
DSMPHX
Des Moines
Wed 9/16
2:40 pm-7:00 pm
1 stop6h 20m
Phoenix Sky Harbor Intl
Tue 9/22
6:20 am-1:55 pm
1 stop5h 35m
$341
Des MoinesPhoenix
DSM - PHX
DSMPHX
Des Moines
Sat 9/19
10:59 am-3:58 pm
1 stop6h 59m
Phoenix Sky Harbor Intl
Sat 10/3
7:05 am-2:06 pm
1 stop5h 01m
$341
Des MoinesPhoenix
DSM - PHX
DSMPHX
Des Moines
Wed 9/23
2:40 pm-7:00 pm
1 stop6h 20m
Phoenix Sky Harbor Intl
Wed 10/7
12:00 pm-9:50 pm
2 stops7h 50m
$346
Des MoinesPhoenix
DSM - PHX
DSMPHX
Des Moines
Wed 9/2
6:10 am-12:35 pm
1 stop8h 25m
Phoenix Sky Harbor Intl
Wed 9/9
11:35 am-9:55 pm
2 stops8h 20m
$346
Des MoinesPhoenix
DSM - PHX
DSMPHX
Des Moines
Sat 9/19
12:10 pm-5:45 pm
2 stops7h 35m
Phoenix Sky Harbor Intl
Sat 10/3
11:00 am-8:35 pm
2 stops7h 35m
$397
Des MoinesPhoenix
DSM - PHX
DSMPHX
Des Moines
Wed 7/15
3:45 pm-10:55 pm
2 stops9h 10m
Phoenix Sky Harbor Intl
Wed 7/22
10:40 am-9:45 pm
2 stops9h 05m
$413
Des MoinesPhoenix
DSM - PHX
DSMPHX
Des Moines
Sun 9/6
6:00 am-1:50 pm
1 stop9h 50m
Phoenix Sky Harbor Intl
Fri 9/11
11:05 pm-9:33 am
1 stop8h 28m
$418
Quickest round-trip
Des MoinesPhoenix
DSM - PHX
DSMPHX
Des Moines
Tue 9/8
5:21 pm-8:24 pm
1 stop5h 03m
Phoenix Sky Harbor Intl
Sat 9/12
6:09 am-2:14 pm
1 stop6h 05m
$431
Des MoinesPhoenix
DSM - PHX
DSMPHX
Des Moines
Tue 8/18
3:20 pm-10:21 pm
1 stop9h 01m
Phoenix Sky Harbor Intl
Wed 8/19
9:00 am-5:28 pm
1 stop6h 28m
$431
Des MoinesPhoenix
DSM - PHX
DSMPHX
Des Moines
Wed 8/26
1:35 pm-8:37 pm
2 stops9h 02m
Phoenix Sky Harbor Intl
Sat 8/29
6:09 am-2:14 pm
1 stop6h 05m
$436
Showing 1-10 of 21 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Mesa
Have a flexible travel schedule? Discover the best time to fly to Mesa from Des Moines with our price prediction graph.
DSM-PHX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Mesa
DSM-MS9
DSM-PHX
What is the cheapest time of day to fly from DSM to MS9?
Find hourly flight availability from Des Moines to Mesa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 25, 2026.
One of the essential ways to save on airfare from Des Moines to Mesa is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight at noon could potentially save you up to 40% on airfare.
Weekly flight availability from Des Moines to Mesa
Explore weekly flight availability from Des Moines to Mesa. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated June 25, 2026.
The most flights from DSM to MS9 are scheduled on a Wednesday (4 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (2 on average).
How much does it cost to fly round-trip from Des Moines to Mesa?
Reviews of airlines servicing Mesa
Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated June 25, 2026.
Read reviews from past customers who have flown Southwest,United Airlines, andAllegiant Air from Des Moines to Mesa. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Comfort
8.0
Food
7.0
Boarding
8.1
Overall
7.9
Crew
8.6
Reviews
1 / 20
10.0
ExcellentSherrie,Jan 2024
LAX - PHX
Entertainment
7.5
Comfort
8.0
Food
7.0
Boarding
8.1
Overall
7.9
Crew
8.6
Reviews
1 / 20
10.0
ExcellentSherrie,Jan 2024
LAX - PHX
Entertainment
7.5
Comfort
8.0
Food
7.0
Boarding
8.1
Overall
7.9
Crew
8.6
Reviews
1 / 20
10.0
ExcellentSherrie,Jan 2024
LAX - PHX
Entertainment
7.5
Comfort
8.0
Food
7.0
Boarding
8.1
Overall
7.9
Crew
8.6
Reviews
1 / 20
10.0
ExcellentSherrie,Jan 2024
LAX - PHX
Entertainment
7.5
Comfort
8.0
Food
7.0
Boarding
8.1
Overall
7.9
Crew
8.6
Reviews
1 / 20
10.0
ExcellentSherrie,Jan 2024
LAX - PHX
Entertainment
7.5
Comfort
8.0
Food
7.0
Boarding
8.1
Overall
7.9
Crew
8.6
Reviews
1 / 20
10.0
ExcellentSherrie,Jan 2024
LAX - PHX
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Des Moines and Mesa flights
Browse other Des Moines and Mesa flight options. Last updated on June 25, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on June 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Des Moines to Mesa flights
Consider these flights traveling from Des Moines to Mesa.
Top 7 airlines flying from Des Moines to Mesa
Discover the top 7 airlines that operate flights from Des Moines to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$133 | Average$259 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$152 | Average$302 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$161 | Average$275 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$180 | Average$354 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$197 | Average$356 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$212 | Average$391 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$219 | Average$328 | FlexibilityNo cancel fee | On-time62% |