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$90+ Cheap flights from Des Moines (DSM) to Mesa, AZ

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/8. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — PHX
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheapflights Tip: The best prices from Des Moines to Mesa are usually found in January or November, booked 50 days in advance, depart on a Tuesday or Wednesday and return on a Tuesday

Cheap flight deals from Des Moines to Mesa

Keep the following information in mind while searching for Des Moines to Mesa flight deals. Data was last updated June 12, 2025.

Round-trip from

$189
(American Airlines)

One-way from

$93
(Mytrip)

Popular in

March

Cheapest in

January

Average price

$333
From Des Moines to Mesa
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One-way flight from Des Moines to Mesa
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Highest demand for flights based on searches. 11% potential increase in price ($45 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Des Moines to Mesa

Cheapest flights from Des Moines to Mesa
Explore the most affordable flight options available from Des Moines to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/225:35 amDSM - PHX
Nonstop3h 02mAmerican Airlines
Sat 7/267:09 pmPHX - DSM
Nonstop2h 50mAmerican Airlines
Deal found 6/11$189
This CheapOair deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/28:41 pmDSM - PHX
1 stop12h 58mFrontier
Sun 10/56:25 pmPHX - DSM
1 stop23h 31mFrontier
Deal found 6/10$212
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/11:35 pmDSM - PHX
1 stop7h 30mSouthwest
Mon 8/44:40 pmPHX - DSM
1 stop4h 15mSouthwest
Deal found 6/11$214
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/45:40 amDSM - PHX
1 stop8h 55mDelta
Tue 8/510:50 amPHX - DSM
1 stop7h 43mDelta
Deal found 6/9$237
This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/106:32 pmDSM - PHX
2 stops30h 02mMultiple Airlines
Thu 7/174:57 pmPHX - DSM
2 stops17h 28mMultiple Airlines
Deal found 6/11$292
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/176:25 amDSM - PHX
2 stops7h 53mUnited Airlines
Tue 6/242:43 pmPHX - DSM
1 stop6h 02mUnited Airlines
Deal found 6/11$334

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Des Moines to Mesa that are best for you.

Fly from

Des Moines

Fly to

Mesa

Route

Depart

Return

Price

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Tue 7/22

5:35 am-6:37 am

Nonstop3h 02m

Phoenix Sky Harbor Intl

Sat 7/26

7:09 pm-11:59 pm

Nonstop2h 50m

$189

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Thu 10/2

8:41 pm-7:39 am

1 stop12h 58m

Phoenix Sky Harbor Intl

Sun 10/5

6:25 pm-7:56 pm

1 stop23h 31m

$212

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Fri 8/1

1:35 pm-7:05 pm

1 stop7h 30m

Phoenix Sky Harbor Intl

Mon 8/4

4:40 pm-10:55 pm

1 stop4h 15m

$214

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Fri 7/4

6:07 am-1:46 pm

1 stop9h 39m

Phoenix Sky Harbor Intl

Fri 7/11

12:45 am-10:16 am

1 stop7h 31m

$237

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Thu 7/10

6:32 pm-10:34 pm

2 stops30h 02m

Phoenix Sky Harbor Intl

Thu 7/17

4:57 pm-12:25 pm

2 stops17h 28m

$292

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Wed 6/25

1:30 pm-8:39 pm

2 stops9h 09m

Phoenix Sky Harbor Intl

Sat 6/28

1:35 pm-8:15 pm

1 stop4h 40m

$334

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Wed 10/8

7:30 am-11:17 am

1 stop5h 47m

$90

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Tue 7/15

5:35 am-6:37 am

Nonstop3h 02m

$95

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Fri 7/4

1:15 pm-6:20 pm

1 stop7h 05m

$107

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Tue 7/15

2:39 pm-8:03 pm

1 stop7h 24m

$119

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Showing 1-10 of 13 results
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Best time to book a flight from Des Moines to Mesa

Have a flexible travel schedule? Discover the best time to fly to Mesa from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Mesa

How far ahead should I book a flight from Des Moines to Mesa?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Mesa. Price data was last updated on June 9, 2025.

To ensure you get the cheapest price possible for a flight from Des Moines to Mesa, you should look to book at least 50 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Des Moines to Mesa?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Mesa (average of $258). Flying from Des Moines to Mesa in March is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to MS9?

Find hourly flight availability from Des Moines to Mesa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Mesa as you normally would.

What is the cheapest day to fly from Des Moines to Mesa?

Use this chart to determine the cheapest time to fly round-trip from Des Moines to Mesa. Price data was last updated on June 8, 2025.

Travelers seeking maximum savings on their Des Moines to Mesa flight should consider departing on Wednesday evenings when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Des Moines to Mesa

Explore weekly flight availability from Des Moines to Mesa. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated June 12, 2025.

The most flights from DSM to MS9 are scheduled on a Monday (4 on average). You will have fewer flight options on Sunday, which is when the least amount of flights are scheduled (2 on average).

Rainfall in Mesa by month

Plan your trip to Mesa by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Mesa ranges from 0.0 - 1.1 inches per month. July is typically the wettest month, when rainfall can reach 1.1 in. June is typically the driest time to visit Mesa when rainfall is around 0.0 in.

Temperature in Mesa by month

Plan your trip to Mesa by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Mesa, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 95.0 F. Travelers looking to avoid the cold should look outside of December, when temperatures are typically at their lowest (around 55.4 F).

Reviews of airlines servicing Mesa

Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated June 12, 2025.
Read reviews from past customers who have flown Southwest, Delta and United Airlines from Des Moines to Mesa. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,287 reviews

Boarding

8.2

Comfort

8.0

Entertainment

7.6

Overall

8.0

Food

7.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Southwest
8.0
Very good
4,287 reviews
Southwest
8.0
Very good
4,287 reviews

Boarding

8.2

Comfort

8.0

Entertainment

7.6

Overall

8.0

Food

7.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Delta
8.0
Very good
7,946 reviews
Southwest
8.0
Very good
4,287 reviews

Boarding

8.2

Comfort

8.0

Entertainment

7.6

Overall

8.0

Food

7.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
United Airlines
7.4
Good
8,790 reviews
Southwest
8.0
Very good
4,287 reviews

Boarding

8.2

Comfort

8.0

Entertainment

7.6

Overall

8.0

Food

7.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Allegiant Air
7.3
Good
725 reviews
Southwest
8.0
Very good
4,287 reviews

Boarding

8.2

Comfort

8.0

Entertainment

7.6

Overall

8.0

Food

7.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,287 reviews

Boarding

8.2

Comfort

8.0

Entertainment

7.6

Overall

8.0

Food

7.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Mesa?

    Located just 3.6 mi from the city center, Des Moines is the airport most travelers will use when flying to Mesa from Des Moines. Booking flights from Des Moines (DSM) to Mesa should be relatively easy as there are 3 daily outbound flights to Mesa from 6 different airlines.

  • What are the cheapest airlines to fly from Des Moines to Mesa one-way?

    $95 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on Southwest and Delta, with prices starting from $107 and $119, respectively.

  • What are the most reliable airlines from Des Moines to Mesa?

    Before booking your flight to Mesa from Des Moines, check out the most reliable airlines to get you to your destination on time: Envoy Air (94%), SkyWest Airlines (90%), Alaska Airlines( 83%).

  • What are the cheapest flights from Des Moines to Mesa?

    Looking at all options, your cheapest flight can be booked for $98. While the most popular route (Des Moines - Phoenix Sky Harbor Intl) can be booked for $214 on average our data indicates $312 when flying from Des Moines to Mesa.

  • Can I find deals for flights from Des Moines to Mesa that include hotel bookings?

    Yes. In addition to deals on Des Moines to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Mesa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Mesa.

  • Can I find deals for business class flights from Des Moines to Mesa?

    Yes. Cheapflights offers flight deals from Des Moines to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Mesa?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Mesa (average of $258). Flying from Des Moines to Mesa in March is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 6 airlines flying from Des Moines to Mesa

Discover the top 6 airlines that operate flights from Des Moines to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$106Average$254FlexibilityNo cancel feeOn-time62%
Allegiant AirCheapest$116Average$227FlexibilityNo cancel feeOn-time88%
SouthwestCheapest$199Average$329FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$204Average$356FlexibilityNo cancel feeOn-time71%
DeltaCheapest$236Average$473FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$241Average$410FlexibilityNo cancel feeOn-time69%

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