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$164+ Cheap flights from Des Moines to Manchester, NH (DSM - MHT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/18. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MHT
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Des Moines to Manchester

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Manchester (MHT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2025.

Round-trip from

$297
(American Airlines)

One-way from

$164
(American Airlines)

Popular in

April

Cheapest in

July

Average price

$286
From Des Moines to Manchester
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One-way flight from Des Moines to Manchester
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Highest demand for flights based on searches. 9% potential increase in price ($34 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Des Moines to Manchester

Cheapest flights from Des Moines to Manchester
Explore the most affordable flight options available from Des Moines to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/146:07 pmDSM - MHT
1 stop4h 49mAmerican Airlines
Wed 10/225:15 pmMHT - DSM
1 stop7h 44mAmerican Airlines
Deal found 9/13$297
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/224:16 pmDSM - MHT
1 stop5h 36mAmerican Airlines
Mon 11/245:20 pmMHT - DSM
1 stop7h 35mAmerican Airlines
Deal found 9/12$417
This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/196:50 pmDSM - MHT
2 stops12h 10mSouthwest
Mon 1/512:30 pmMHT - DSM
2 stops12h 05mSouthwest
Deal found 9/11$425
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/273:25 pmDSM - MHT
2 stops22h 37mUnited Airlines
Wed 10/19:40 amMHT - DSM
2 stops8h 44mUnited Airlines
Deal found 9/12$545
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/146:36 pmDSM - MHT
2 stops19h 26mUnited Airlines
Wed 10/229:40 amMHT - DSM
2 stops10h 39mUnited Airlines
Deal found 9/13$556
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/273:15 pmDSM - MHT
2 stops7h 29mUnited Airlines
Mon 11/32:27 pmMHT - DSM
2 stops31h 18mUnited Airlines
Deal found 9/11$582
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/168:00 amDSM - MHT
1 stop13h 51mAmerican Airlines
Wed 9/2412:08 pmMHT - DSM
1 stop12h 37mAmerican Airlines
Deal found 9/14$714
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/198:00 amDSM - MHT
3 stops9h 51mUnited Airlines
Mon 1/52:23 pmMHT - DSM
2 stops8h 17mUnited Airlines
Deal found 9/11$723

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Des Moines to Manchester that are best for you.

Fly from

Des Moines

Fly to

Manchester

Route

Depart

Return

Price

Des MoinesManchester

DSM - MHT

DSMMHT

Des Moines

Sat 11/22

4:16 pm-10:52 pm

1 stop5h 36m

Manchester

Mon 11/24

5:20 pm-11:55 pm

1 stop7h 35m

$417

Des MoinesManchester

DSM - MHT

DSMMHT

Des Moines

Tue 10/14

3:56 pm-11:51 pm

1 stop6h 55m

Manchester

Wed 10/22

6:00 am-3:26 pm

2 stops10h 26m

$444

Des MoinesManchester

DSM - MHT

DSMMHT

Des Moines

Sat 9/27

3:25 pm-3:02 pm

2 stops22h 37m

Manchester

Wed 10/1

9:40 am-5:24 pm

2 stops8h 44m

$545

Des MoinesManchester

DSM - MHT

DSMMHT

Des Moines

Tue 10/14

6:36 pm-3:02 pm

2 stops19h 26m

Manchester

Wed 10/22

9:40 am-7:19 pm

2 stops10h 39m

$556

Des MoinesManchester

DSM - MHT

DSMMHT

Des Moines

Mon 10/27

3:15 pm-11:44 pm

2 stops7h 29m

Manchester

Mon 11/3

2:27 pm-8:45 pm

2 stops31h 18m

$582

Des MoinesManchester

DSM - MHT

DSMMHT

Des Moines

Thu 9/18

6:00 am-11:38 am

1 stop4h 38m

Manchester

Sun 9/21

7:03 am-1:51 pm

1 stop7h 48m

$767

Des MoinesManchester

DSM - MHT

DSMMHT

Des Moines

Sat 10/18

6:00 am-3:00 pm

1 stop8h 00m

$164

Des MoinesManchester

DSM - MHT

DSMMHT

Des Moines

Sat 10/4

10:21 am-5:29 pm

1 stop6h 08m

$169

Des MoinesManchester

DSM - MHT

DSMMHT

Des Moines

Tue 9/30

3:50 pm-12:09 am

1 stop7h 19m

$218

Des MoinesManchester

DSM - MHT

DSMMHT

Des Moines

Sat 9/27

10:21 am-5:29 pm

1 stop6h 08m

$234

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Showing 1-10 of 16 results
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Best time to book a flight from Des Moines to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Manchester

What is the cheapest month to book a flight from Des Moines to Manchester, New Hampshire?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Manchester, New Hampshire (average of $334). Flying from Des Moines to Manchester, New Hampshire in April is currently the most expensive (average of $397). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Manchester

Get insights into the airlines that provide service to Manchester. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Manchester. Reviews last updated September 15, 2025.
See what other customers who have flown with American Airlines from Des Moines to Manchester have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Overall

7.2

Entertainment

6.9

Boarding

7.5

Food

6.4

Comfort

7.2

Crew

8.0

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Overall

7.2

Entertainment

6.9

Boarding

7.5

Food

6.4

Comfort

7.2

Crew

8.0

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Manchester, New Hampshire?

    A quick flight from Des Moines to Manchester, New Hampshire can take about 5h 36m. American Airlines provides one of the quickest options available for as low as $417. The distance between Des Moines and Manchester, New Hampshire is about 1137 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Des Moines to Manchester, New Hampshire round-trip?

    Flying on American Airlines is currently your cheapest option to Manchester, New Hampshire, with prices starting at $310.

  • Can I find deals for flights from Des Moines to Manchester that include hotel bookings?

    Yes. In addition to deals on Des Moines to Manchester flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Manchester.

  • Can I find deals for business class flights from Des Moines to Manchester?

    Yes. Cheapflights offers flight deals from Des Moines to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Manchester, New Hampshire?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Manchester, New Hampshire (average of $334). Flying from Des Moines to Manchester, New Hampshire in April is currently the most expensive (average of $397). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
Keene

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Top airline flying from Des Moines to Manchester

Discover the top airline that operate flights from Des Moines to Manchester. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$316Average$433FlexibilityNo cancel feeOn-time71%

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