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$143+ Cheap flights from Key West to Louisville (EYW - SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/31. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — SDF
Dec 13 — Dec 201
Sat 12/13
Sat 12/20
1 adult, Economy
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Cheap flight deals from Key West to Louisville

Discover tips and strategies to find the most affordable flight options for your journey from Key West (EYW) to Louisville (SDF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 13, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$311
(Delta)

One-way from

$273
(Kiwi.com)
Provider with most accurate pricing for Key West-Louisville Intl flight deals.
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Provider most trusted by Cheapflights users for Key West-Louisville Intl flights.
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From Key West to Louisville Intl
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One-way flight from Key West to Louisville Intl
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Find flight deals from Key West to Louisville

Cheapest flights from Key West to Louisville
Explore the most affordable flight options available from Key West to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2025.

This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/47:40 amEYW - SDF
1 stop6h 31mDelta
Wed 12/1012:58 pmSDF - EYW
1 stop7h 08mDelta
Deal found 11/11$311
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/264:00 pmEYW - SDF
1 stop6h 29mUnited Airlines
Sun 11/307:00 amSDF - EYW
1 stop8h 19mUnited Airlines
Deal found 11/10$384
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/412:00 pmEYW - SDF
2 stops10h 00mAmerican Airlines
Wed 12/107:00 amSDF - EYW
1 stop6h 51mAmerican Airlines
Deal found 11/11$415
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/264:10 pmEYW - SDF
1 stop7h 31mAmerican Airlines
Sun 11/306:00 amSDF - EYW
2 stops8h 14mAmerican Airlines
Deal found 11/10$494

Cheapflights Fare Finder

 
Customize your flight search to find flights from Key West to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from Key West to Louisville that are best for you.

Fly from

Key West

Fly to

Louisville

Route

Depart

Return

Price

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Thu 12/4

7:40 am-2:11 pm

1 stop6h 31m

Louisville Intl

Wed 12/10

12:58 pm-8:06 pm

1 stop7h 08m

$311

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Fri 3/6

6:07 pm-11:50 pm

1 stop5h 43m

Louisville Intl

Mon 3/9

2:59 pm-7:44 pm

1 stop4h 45m

$339

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Wed 11/26

4:00 pm-10:29 pm

1 stop6h 29m

Louisville Intl

Sun 11/30

7:00 am-3:19 pm

1 stop8h 19m

$384

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Thu 12/4

12:00 pm-10:00 pm

2 stops10h 00m

Louisville Intl

Wed 12/10

7:00 am-1:51 pm

1 stop6h 51m

$415

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Fri 3/6

4:02 pm-12:25 am

2 stops8h 23m

Louisville Intl

Mon 3/9

12:23 pm-4:44 pm

1 stop4h 21m

$436

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Wed 11/26

4:10 pm-11:41 pm

1 stop7h 31m

Louisville Intl

Sun 11/30

6:00 am-2:14 pm

2 stops8h 14m

$494

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Wed 12/31

2:30 pm-11:59 pm

1 stop9h 29m

$143

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Wed 12/31

7:47 am-2:15 pm

2 stops30h 28m

$194

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Wed 12/31

7:47 am-7:23 pm

1 stop11h 36m

$215

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Sat 1/3

10:35 pm-8:58 am

2 stops34h 23m

$273

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/13

Showing 1-10 of 14 results
1
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Compare providers for flights from Key West to Louisville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Key West to Louisville in November.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Key West-Louisville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Key West-Louisville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Key West-Louisville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Key West-Louisville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Key West-Louisville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Key West to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Key West with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key West to Louisville

What is the cheapest time of day to fly from EYW to SDF?

Find hourly flight availability from Key West to Louisville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 13, 2025.

A simple way to save on the total cost of your ticket is to fly from Key West to Louisville in the afternoon. If you’re flexible enough to do this you can expect to save up to 54% on your trip compared to booking a flight in the evening.

Related info for your journey

Find useful and relevant information for your journey from Key West to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Key West to Louisville?

    There are many flights that can get you from Key West to Louisville in 6h 29m. Fly via Delta, United Airlines, or American Airlines to get the fastest option. The distance from Key West to Louisville is about 969 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Key West to Louisville that include hotel bookings?

    Yes. In addition to deals on Key West to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key West to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key West to Louisville.

  • Can I find deals for business class flights from Key West to Louisville?

    Yes. Cheapflights offers flight deals from Key West to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Jeffersonville
Elizabethtown
Corydon
Bardstown

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