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$109+ Cheap flights from Key West to Louisville (EYW - SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/18. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — SDF
Aug 16 — Aug 231
Sat 8/16
Sat 8/23
1 adult, Economy
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Cheap flight deals from Key West to Louisville

Discover tips and strategies to find the most affordable flight options for your journey from Key West (EYW) to Louisville (SDF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 11, 2025.

Round-trip from

$283
(American Airlines)

One-way from

$109
(Kiwi.com)
From Key West to Louisville Intl
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One-way flight from Key West to Louisville Intl
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Find flight deals from Key West to Louisville

Cheapest flights from Key West to Louisville
Explore the most affordable flight options available from Key West to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 11, 2025.

This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/41:52 pmEYW - SDF
1 stop6h 27mAmerican Airlines
Wed 11/126:00 amSDF - EYW
1 stop7h 01mAmerican Airlines
Deal found 8/10$283
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/87:31 pmEYW - SDF
1 stop4h 27mAmerican Airlines
Thu 9/186:31 amSDF - EYW
1 stop4h 23mAmerican Airlines
Deal found 8/11$393

Cheapflights Fare Finder

 
Customize your flight search to find flights from Key West to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 11, 2025.
Use the filters below to find and compare flights from Key West to Louisville that are best for you.

Fly from

Key West

Fly to

Louisville

Route

Depart

Return

Price

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Tue 11/4

1:52 pm-8:19 pm

1 stop6h 27m

Louisville Intl

Wed 11/12

6:00 am-1:01 pm

1 stop7h 01m

$283

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Mon 9/8

7:31 pm-11:58 pm

1 stop4h 27m

Louisville Intl

Thu 9/18

6:31 am-10:54 am

1 stop4h 23m

$393

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Thu 9/18

4:50 pm-7:23 pm

1 stop26h 33m

$109

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Thu 2/5

10:27 pm-10:07 am

1 stop11h 40m

$137

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Mon 11/10

8:47 am-11:45 pm

1 stop14h 58m

$150

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Sun 2/1

10:27 pm-10:07 am

1 stop11h 40m

$165

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Fri 2/6

9:49 am-9:54 am

2 stops24h 05m

$196

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Thu 9/18

12:29 pm-9:19 am

3 stops20h 50m

$218

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Thu 2/5

9:46 am-9:54 am

2 stops24h 08m

$219

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Sun 2/1

11:01 am-9:54 am

2 stops22h 53m

$221

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/10

Best time to book a flight from Key West to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Key West with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key West to Louisville

What is the cheapest time of day to fly from EYW to SDF?

Find hourly flight availability from Key West to Louisville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 11, 2025.

A simple way to save on the total cost of your ticket is to fly from Key West to Louisville at noon. If you’re flexible enough to do this you can expect to save up to 29% on your trip compared to booking a flight in the morning.

Reviews of airlines servicing Louisville

Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated August 11, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Key West to Louisville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,979 reviews

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
8.0
Very good
7,979 reviews
Delta
8.0
Very good
7,979 reviews

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
United Airlines
7.4
Good
8,920 reviews
Delta
8.0
Very good
7,979 reviews

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,979 reviews

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Allegiant Air
7.2
Good
702 reviews
Delta
8.0
Very good
7,979 reviews

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Key West to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What is the cheapest airline to fly from Key West to Louisville round-trip?

    According to our current data, American Airlines ($283), offers the cheapest pricing from Key West to Louisville.

  • Can I find deals for flights from Key West to Louisville that include hotel bookings?

    Yes. In addition to deals on Key West to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key West to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key West to Louisville.

  • Can I find deals for business class flights from Key West to Louisville?

    Yes. Cheapflights offers flight deals from Key West to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Key West to Louisville?

    Currently, January is the cheapest month in which you can book a flight from Key West to Louisville (average of $299). Flying from Key West to Louisville in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Jeffersonville
Elizabethtown
Corydon
Bardstown

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