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$246+ Cheap flights from Greenville to Louisville (GSP - SDF)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/1. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — SDF
Dec 21 — Dec 281
Sun 12/21
Sun 12/28
1 adult, Economy
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Find flight deals from Greenville to Louisville

Cheapest flights from Greenville to Louisville
Explore the most affordable flight options available from Greenville to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 21, 2025.

This Delta deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/35:35 amGSP - SDF
1 stop4h 15mDelta
Sat 12/67:15 amSDF - GSP
1 stop5h 59mDelta
Deal found 11/19$257
This American Airlines deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:00 amGSP - SDF
1 stop6h 30mAmerican Airlines
Sat 12/65:28 pmSDF - GSP
2 stops6h 29mAmerican Airlines
Deal found 11/19$262
This Delta deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/53:23 pmGSP - SDF
1 stop3h 29mDelta
Tue 12/912:58 pmSDF - GSP
1 stop3h 34mDelta
Deal found 11/20$344
This American Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/56:39 amGSP - SDF
1 stop4h 38mAmerican Airlines
Tue 12/94:57 pmSDF - GSP
2 stops6h 07mAmerican Airlines
Deal found 11/20$349
This American Airlines deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:00 amGSP - SDF
1 stop6h 30mAmerican Airlines
Sat 12/136:20 amSDF - GSP
1 stop4h 31mAmerican Airlines
Deal found 11/19$351
This American Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/276:40 amGSP - SDF
1 stop5h 33mAmerican Airlines
Fri 11/2811:10 amSDF - GSP
1 stop7h 51mAmerican Airlines
Deal found 11/20$402
This Southwest deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1110:35 amGSP - SDF
2 stops12h 30mSouthwest
Sat 12/137:10 amSDF - GSP
2 stops6h 05mSouthwest
Deal found 11/19$441
This United Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2710:00 amGSP - SDF
1 stop4h 45mUnited Airlines
Fri 11/287:00 amSDF - GSP
2 stops7h 20mUnited Airlines
Deal found 11/20$442
This American Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/247:52 amGSP - SDF
1 stop8h 58mAmerican Airlines
Fri 11/2812:43 pmSDF - GSP
1 stop9h 21mAmerican Airlines
Deal found 11/20$485

Cheap flight deals from Greenville to Louisville

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Louisville (SDF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 21, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$246
(American Airlines)

Popular in

December

Cheapest in

October

Average price

$412
Provider with most accurate pricing for Greenville-Louisville Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Greenville-Louisville Intl flights.
Search Deals
From Greenville to Louisville Intl
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($39 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 21, 2025.
Use the filters below to find and compare flights from Greenville to Louisville that are best for you.

Fly from

Greenville

Fly to

Louisville

Route

Depart

Return

Price

GreenvilleLouisville

GSP - SDF

GSPSDF

Greenville

Thu 1/1

7:30 am-1:12 pm

1 stop5h 42m

Louisville Intl

Mon 1/5

6:00 am-9:19 am

1 stop3h 19m

$246

GreenvilleLouisville

GSP - SDF

GSPSDF

Greenville

Wed 12/3

5:35 am-9:50 am

1 stop4h 15m

Louisville Intl

Sat 12/6

7:15 am-1:14 pm

1 stop5h 59m

$257

GreenvilleLouisville

GSP - SDF

GSPSDF

Greenville

Wed 12/3

6:00 am-12:30 pm

1 stop6h 30m

Louisville Intl

Sat 12/6

5:28 pm-11:57 pm

2 stops6h 29m

$262

GreenvilleLouisville

GSP - SDF

GSPSDF

Greenville

Thu 1/1

5:39 am-10:54 am

1 stop5h 15m

Louisville Intl

Mon 1/5

5:00 am-8:36 am

1 stop3h 36m

$306

GreenvilleLouisville

GSP - SDF

GSPSDF

Greenville

Fri 2/20

7:40 pm-12:45 am

1 stop5h 05m

Louisville Intl

Thu 2/26

5:30 am-7:05 pm

2 stops13h 35m

$310

GreenvilleLouisville

GSP - SDF

GSPSDF

Greenville

Thu 3/26

12:25 pm-3:50 pm

1 stop3h 25m

Louisville Intl

Thu 3/26

5:15 pm-9:50 pm

1 stop4h 35m

$327

GreenvilleLouisville

GSP - SDF

GSPSDF

Greenville

Fri 12/5

3:23 pm-6:52 pm

1 stop3h 29m

Louisville Intl

Tue 12/9

12:58 pm-4:32 pm

1 stop3h 34m

$344

GreenvilleLouisville

GSP - SDF

GSPSDF

Greenville

Fri 12/5

6:39 am-11:17 am

1 stop4h 38m

Louisville Intl

Tue 12/9

4:57 pm-11:04 pm

2 stops6h 07m

$349

GreenvilleLouisville

GSP - SDF

GSPSDF

Greenville

Thu 12/11

6:00 am-12:30 pm

1 stop6h 30m

Louisville Intl

Sat 12/13

5:28 pm-11:57 pm

2 stops6h 29m

$356

GreenvilleLouisville

GSP - SDF

GSPSDF

Greenville

Wed 11/26

5:28 pm-10:29 pm

1 stop5h 01m

$254

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/18

Showing 1-10 of 15 results
1
2

Compare providers for flights from Greenville to Louisville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to Louisville in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Greenville-Louisville flights, users find the pricing of Mytrip to be most consistent on Cheapflights vs. Mytrip Users can find the same prices on Greenville-Louisville flight deals on Cheapflights vs. Mytrip >95% of the time. Price accuracy is based on data collected from Greenville-Louisville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Greenville-Louisville flights, Cheapflights users trust Mytrip the most. Mytrip has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-Louisville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Greenville to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Louisville

What is the cheapest month to book a flight from Greenville to Louisville?

Currently, April is the cheapest month in which you can book a flight from Greenville to Louisville (average of $148). Flying from Greenville to Louisville in January is currently the most expensive (average of $228). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GSP to SDF?

Find hourly flight availability from Greenville to Louisville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 21, 2025.

One of the essential ways to save on airfare from Greenville to Louisville is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight at noon could potentially save you up to 35% on airfare.

Reviews of airlines servicing Louisville

Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated November 21, 2025.
Peruse reviews from past customers who have flown with Delta and American Airlines from Greenville to Louisville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,002 reviews

Comfort

7.9

Crew

8.5

Food

7.3

Boarding

8.1

Entertainment

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,002 reviews
Delta
7.9
Good
8,002 reviews

Comfort

7.9

Crew

8.5

Food

7.3

Boarding

8.1

Entertainment

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,047 reviews
Delta
7.9
Good
8,002 reviews

Comfort

7.9

Crew

8.5

Food

7.3

Boarding

8.1

Entertainment

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Greenville to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Greenville to Louisville?

    A quick flight from Greenville to Louisville can take about 5h 42m. Delta provides one of the quickest options available for as low as $246. Airlines will cover a distance of 299 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Greenville to Louisville round-trip?

    American Airlines, at $196, was found to be the cheapest airline from Greenville to Louisville. An alternate airline flying to your destination would be Delta. American Airlines is currently priced 48% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Greenville to Louisville one-way?

    For one-way options, check prices for United Airlines. According to our data, you can fly for as low as $254. Users have also found prices from $279 and $284 on Delta and Southwest, respectively.

  • Can I find deals for flights from Greenville to Louisville that include hotel bookings?

    Yes. In addition to deals on Greenville to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Louisville.

  • Can I find deals for business class flights from Greenville to Louisville?

    Yes. Cheapflights offers flight deals from Greenville to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Louisville?

    Currently, April is the cheapest month in which you can book a flight from Greenville to Louisville (average of $148). Flying from Greenville to Louisville in January is currently the most expensive (average of $228). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Jeffersonville
Elizabethtown
Corydon
Bardstown

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Top 2 airlines flying from Greenville to Louisville

Discover the top 2 airlines that operate flights from Greenville to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$196Average$347FlexibilityNo cancel feeOn-time71%
DeltaCheapest$251Average$341FlexibilityNo cancel feeOn-timeN/A

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