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$129+ Cheap flights from Des Moines to Louisville (DSM - SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/29. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SDF
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheap flight deals from Des Moines to Louisville

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Louisville (SDF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2025.

Round-trip from

$249
(Delta)

One-way from

$129
(Mytrip)

Popular in

October

Cheapest in

February

Average price

$329
From Des Moines to Louisville Intl
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One-way flight from Des Moines to Louisville Intl
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Highest demand for flights based on searches. 2% potential increase in price ($8 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Des Moines to Louisville

Cheapest flights from Des Moines to Louisville
Explore the most affordable flight options available from Des Moines to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/265:59 pmDSM - SDF
1 stop5h 33mDelta
Sat 8/24:31 pmSDF - DSM
1 stop5h 26mDelta
Deal found 6/11$249
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/158:02 amDSM - SDF
1 stop3h 58mUnited Airlines
Sun 11/167:30 amSDF - DSM
1 stop4h 00mUnited Airlines
Deal found 6/10$270
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/232:06 pmDSM - SDF
2 stops32h 32mMultiple Airlines
Wed 6/255:03 amSDF - DSM
2 stops42h 34mMultiple Airlines
Deal found 6/10$286
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/104:08 pmDSM - SDF
1 stop6h 14mAmerican Airlines
Mon 9/155:18 pmSDF - DSM
1 stop6h 49mAmerican Airlines
Deal found 6/12$309
This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/261:13 pmDSM - SDF
2 stops24h 07mAllegiant Air
Sat 8/23:36 pmSDF - DSM
2 stops32h 02mAllegiant Air
Deal found 6/11$336
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/156:25 amDSM - SDF
2 stops8h 25mSouthwest
Sun 11/161:55 pmSDF - DSM
2 stops10h 40mSouthwest
Deal found 6/10$345

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Des Moines to Louisville that are best for you.

Fly from

Des Moines

Fly to

Louisville

Route

Depart

Return

Price

Des MoinesLouisville

DSM - SDF

DSMSDF

Des Moines

Sat 7/26

5:59 pm-12:32 am

1 stop5h 33m

Louisville Intl

Sat 8/2

4:31 pm-8:57 pm

1 stop5h 26m

$249

Des MoinesLouisville

DSM - SDF

DSMSDF

Des Moines

Mon 6/23

2:06 pm-11:38 pm

2 stops32h 32m

Louisville Intl

Wed 6/25

5:03 am-10:37 pm

2 stops42h 34m

$286

Des MoinesLouisville

DSM - SDF

DSMSDF

Des Moines

Sat 9/13

10:09 am-6:39 pm

2 stops7h 30m

Louisville Intl

Sun 9/14

7:35 am-12:58 pm

1 stop6h 23m

$305

Des MoinesLouisville

DSM - SDF

DSMSDF

Des Moines

Sun 9/7

3:25 pm-10:24 pm

1 stop5h 59m

Louisville Intl

Wed 9/10

7:00 am-10:39 am

1 stop4h 39m

$330

Des MoinesLouisville

DSM - SDF

DSMSDF

Des Moines

Sat 7/26

1:13 pm-2:20 pm

2 stops24h 07m

Louisville Intl

Sat 8/2

3:36 pm-10:38 pm

2 stops32h 02m

$336

Des MoinesLouisville

DSM - SDF

DSMSDF

Des Moines

Sat 11/15

6:25 am-3:50 pm

2 stops8h 25m

Louisville Intl

Sun 11/16

1:55 pm-11:35 pm

2 stops10h 40m

$345

Des MoinesLouisville

DSM - SDF

DSMSDF

Des Moines

Sun 6/29

3:48 pm-2:12 pm

1 stop21h 24m

$129

Des MoinesLouisville

DSM - SDF

DSMSDF

Des Moines

Sun 7/27

6:40 pm-12:32 am

1 stop4h 52m

$174

Des MoinesLouisville

DSM - SDF

DSMSDF

Des Moines

Mon 6/23

5:04 pm-9:09 am

1 stop15h 05m

$176

Des MoinesLouisville

DSM - SDF

DSMSDF

Des Moines

Sat 6/28

6:00 am-10:58 pm

2 stops15h 58m

$455

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Best time to book a flight from Des Moines to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Louisville

What is the cheapest month to book a flight from Des Moines to Louisville?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Louisville (average of $299). Flying from Des Moines to Louisville in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Louisville by month

Plan your trip to Louisville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Louisville ranges from 3.1 - 5.3 inches per month. May is typically the wettest month, when rainfall can reach 5.3 in. September is typically the driest time to visit Louisville when rainfall is around 3.1 in.

Temperature in Louisville by month

Plan your trip to Louisville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Louisville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 35.6 F).

Reviews of airlines servicing Louisville

Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated June 12, 2025.
Southwest
8.0
Very good
4,287 reviews

Entertainment

7.6

Boarding

8.2

Comfort

8.0

Food

7.1

Overall

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Southwest
8.0
Very good
4,287 reviews
Southwest
8.0
Very good
4,287 reviews

Entertainment

7.6

Boarding

8.2

Comfort

8.0

Food

7.1

Overall

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Delta
8.0
Very good
7,950 reviews
Southwest
8.0
Very good
4,287 reviews

Entertainment

7.6

Boarding

8.2

Comfort

8.0

Food

7.1

Overall

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
United Airlines
7.4
Good
8,790 reviews
Southwest
8.0
Very good
4,287 reviews

Entertainment

7.6

Boarding

8.2

Comfort

8.0

Food

7.1

Overall

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Allegiant Air
7.3
Good
725 reviews
Southwest
8.0
Very good
4,287 reviews

Entertainment

7.6

Boarding

8.2

Comfort

8.0

Food

7.1

Overall

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,287 reviews

Entertainment

7.6

Boarding

8.2

Comfort

8.0

Food

7.1

Overall

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Des Moines to Louisville round-trip?

    Delta, at $249, was found to be the cheapest airline from Des Moines to Louisville.Alternate airlines to your destination round-trip include American Airlines and United Airlines. Delta is priced at 36% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest airlines to fly from Des Moines to Louisville one-way?

    $174 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on Allegiant Air and United Airlines, with prices starting from $176 and $455, respectively.

  • Can I find deals for flights from Des Moines to Louisville that include hotel bookings?

    Yes. In addition to deals on Des Moines to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Louisville.

  • Can I find deals for business class flights from Des Moines to Louisville?

    Yes. Cheapflights offers flight deals from Des Moines to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Louisville?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Louisville (average of $299). Flying from Des Moines to Louisville in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Shepherdsville
Jeffersonville
Elizabethtown
Corydon
Bardstown

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Top 3 airlines flying from Des Moines to Louisville

Discover the top 3 airlines that operate flights from Des Moines to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$246Average$322FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$264Average$386FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$306Average$410FlexibilityNo cancel feeOn-time69%

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