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$137+ Cheap flights from Des Moines to Louisville (DSM - SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/22. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SDF
Aug 16 — Aug 231
Sun 8/16
Sun 8/23
1 adult, Economy
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Cheap flight deals from Des Moines to Louisville

Cheapest flights from Des Moines to Louisville
Explore the most affordable flight options available from Des Moines to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 17, 2026.

This Delta deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:00 am
DSM
-
SDF
1 stop6h 51m
Delta
Sat 8/156:50 am
SDF
-
DSM
1 stop4h 28m
Delta
Deal found 7/16$273
This Southwest deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/122:40 pm
DSM
-
SDF
1 stop4h 55m
Southwest
Tue 8/185:30 am
SDF
-
DSM
2 stops7h 20m
Southwest
Deal found 7/13$278
This Southwest deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:10 am
DSM
-
SDF
2 stops8h 45m
Southwest
Wed 10/283:55 pm
SDF
-
DSM
2 stops7h 00m
Southwest
Deal found 7/13$283
This Southwest deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/195:30 am
DSM
-
SDF
2 stops14h 50m
Southwest
Sat 9/264:55 pm
SDF
-
DSM
1 stop3h 30m
Southwest
Deal found 7/13$284
This United Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:55 pm
DSM
-
SDF
1 stop4h 04m
United Airlines
Tue 10/1310:25 am
SDF
-
DSM
1 stop4h 50m
United Airlines
Deal found 7/16$287
This United Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:00 am
DSM
-
SDF
2 stops10h 15m
United Airlines
Thu 8/205:15 am
SDF
-
DSM
1 stop6h 11m
United Airlines
Deal found 7/16$301
This United Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3011:27 am
DSM
-
SDF
1 stop6h 44m
United Airlines
Sun 10/47:00 am
SDF
-
DSM
1 stop4h 31m
United Airlines
Deal found 7/12$310
This Southwest deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:10 am
DSM
-
SDF
2 stops9h 10m
Southwest
Sun 10/48:25 pm
SDF
-
DSM
1 stop3h 25m
Southwest
Deal found 7/12$315
This Southwest deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:40 am
DSM
-
SDF
2 stops13h 20m
Southwest
Sat 11/1412:45 pm
SDF
-
DSM
2 stops7h 55m
Southwest
Deal found 7/13$326
This Southwest deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:10 am
DSM
-
SDF
1 stop4h 00m
Southwest
Tue 10/1310:40 am
SDF
-
DSM
2 stops12h 15m
Southwest
Deal found 7/16$327
This Southwest deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:40 am
DSM
-
SDF
2 stops8h 50m
Southwest
Sat 8/159:00 am
SDF
-
DSM
1 stop3h 30m
Southwest
Deal found 7/14$329

Find flight deals from Des Moines to Louisville

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Louisville (SDF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 17, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$273
(Delta)

One-way from

$137
(United Airlines)

Popular in

December

Cheapest in

January

Average price

$435
Provider with most accurate pricing for Des Moines-Louisville Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Louisville Intl flights.
Search Deals
From Des Moines to Louisville Intl
Search Deals
One-way flight from Des Moines to Louisville Intl
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($46 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 17, 2026.
Use the filters below to find and compare flights from Des Moines to Louisville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesLouisville

DSM - SDF

DSMSDF

Des Moines

Tue 8/18

11:32 am-4:38 pm

1 stop4h 06m

Louisville Intl

Thu 8/20

7:10 am-12:20 pm

1 stop6h 10m

$273

Des MoinesLouisville

DSM - SDF

DSMSDF

Des Moines

Thu 11/26

5:45 am-1:49 pm

1 stop7h 04m

Louisville Intl

Tue 12/1

5:45 pm-10:29 pm

1 stop5h 44m

$273

Des MoinesLouisville

DSM - SDF

DSMSDF

Des Moines

Thu 8/6

1:55 pm-9:25 pm

1 stop6h 30m

Louisville Intl

Sat 8/15

7:18 pm-12:35 am

1 stop6h 17m

$273

Des MoinesLouisville

DSM - SDF

DSMSDF

Des Moines

Thu 8/6

6:00 am-1:51 pm

1 stop6h 51m

Louisville Intl

Sat 8/15

6:50 am-10:18 am

1 stop4h 28m

$273

Des MoinesLouisville

DSM - SDF

DSMSDF

Des Moines

Mon 10/26

3:15 pm-10:30 pm

1 stop6h 15m

Louisville Intl

Wed 10/28

10:25 am-2:19 pm

1 stop4h 54m

$273
Quickest round-trip

Des MoinesLouisville

DSM - SDF

DSMSDF

Des Moines

Wed 9/9

1:23 pm-7:07 pm

1 stop4h 44m

Louisville Intl

Thu 9/10

7:10 am-10:31 am

1 stop4h 21m

$273

Des MoinesLouisville

DSM - SDF

DSMSDF

Des Moines

Wed 8/12

6:10 am-11:20 am

1 stop4h 10m

Louisville Intl

Wed 8/19

5:30 am-11:50 am

2 stops7h 20m

$278

Des MoinesLouisville

DSM - SDF

DSMSDF

Des Moines

Wed 9/9

2:40 pm-8:35 pm

1 stop4h 55m

Louisville Intl

Thu 9/10

11:50 am-10:10 pm

2 stops11h 20m

$278

Des MoinesLouisville

DSM - SDF

DSMSDF

Des Moines

Mon 10/26

4:30 pm-9:05 pm

1 stop3h 35m

Louisville Intl

Wed 10/28

3:55 pm-9:55 pm

2 stops7h 00m

$278

Des MoinesLouisville

DSM - SDF

DSMSDF

Des Moines

Thu 8/13

5:40 am-3:30 pm

2 stops8h 50m

Louisville Intl

Mon 8/17

3:20 pm-10:10 pm

2 stops7h 50m

$283

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/16

Showing 1-10 of 17 resultsSorted by cheapest first
1
2

Compare providers for flights from Des Moines to Louisville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Louisville in July.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Louisville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Louisville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Louisville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Louisville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Louisville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Louisville

What is the cheapest month to book a flight from Des Moines to Louisville?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Louisville (average of $260). Flying from Des Moines to Louisville in December is currently the most expensive (average of $626). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Louisville

Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated July 17, 2026.
Read through reviews of airlines operating flights from Des Moines to Louisville, such as Delta,United Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.8
Good
8,474 reviews

Overall

7.8

Comfort

7.8

Entertainment

7.8

Crew

8.5

Food

7.2

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
Delta
7.8
Good
8,474 reviews
Delta
7.8
Good
8,474 reviews

Overall

7.8

Comfort

7.8

Entertainment

7.8

Crew

8.5

Food

7.2

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
United Airlines
7.4
Good
9,997 reviews
Delta
7.8
Good
8,474 reviews

Overall

7.8

Comfort

7.8

Entertainment

7.8

Crew

8.5

Food

7.2

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
American Airlines
7.1
Good
11,818 reviews
Delta
7.8
Good
8,474 reviews

Overall

7.8

Comfort

7.8

Entertainment

7.8

Crew

8.5

Food

7.2

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Louisville?

    United Airlines, Delta, and American Airlines can get you from Des Moines to Louisville in just under 4h 06m. Your travel time can differ by up to 2h 58m. The distance from Des Moines to Louisville is about 480 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Des Moines to Louisville round-trip?

    United Airlines, at $109, was found to be the cheapest airline from Des Moines to Louisville.Alternate airlines to your destination round-trip include Delta and American Airlines. United Airlines is priced at 74% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Des Moines to Louisville that include hotel bookings?

    Yes. In addition to deals on Des Moines to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Louisville.

  • Can I find deals for business class flights from Des Moines to Louisville?

    Yes. Cheapflights offers flight deals from Des Moines to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Louisville?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Louisville (average of $260). Flying from Des Moines to Louisville in December is currently the most expensive (average of $626). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Corydon
Shepherdsville
Elizabethtown
Jeffersonville
Bardstown

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Top 3 airlines flying from Des Moines to Louisville

Discover the top 3 airlines that operate flights from Des Moines to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 17, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$109Average$409FlexibilityNo cancel feeOn-time69%
DeltaCheapest$129Average$432FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$260Average$402FlexibilityNo cancel feeOn-time71%

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