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$489+ Cheap flights from Florence, SC (FLO) to Louisiana

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/25. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — MSY
Mar 7 — Mar 141
Sat 3/7
Sat 3/14
1 adult, Economy
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Cheap flight deals from Florence to Louisiana

Cheapest flights from Florence to Louisiana
Explore the most affordable flight options available from Florence to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 5, 2026.

This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/255:58 pm
FLO
-
MSY
1 stop5h 58m
American Airlines
Sat 2/286:43 pm
MSY
-
FLO
1 stop4h 14m
American Airlines
Deal found 2/3$489
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/216:25 pm
FLO
-
MSY
1 stop6h 34m
American Airlines
Mon 3/2310:49 am
MSY
-
FLO
1 stop6h 01m
American Airlines
Deal found 2/3$540
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/206:20 pm
FLO
-
MSY
1 stop6h 39m
American Airlines
Mon 3/236:43 pm
MSY
-
FLO
1 stop4h 14m
American Airlines
Deal found 2/3$571
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/215:16 am
FLO
-
MSY
1 stop4h 11m
American Airlines
Sun 3/226:43 pm
MSY
-
FLO
1 stop4h 14m
American Airlines
Deal found 2/3$582
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/206:20 pm
FLO
-
MSY
1 stop6h 39m
American Airlines
Sun 3/226:43 pm
MSY
-
FLO
1 stop4h 14m
American Airlines
Deal found 2/3$613
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/135:16 am
FLO
-
MSY
1 stop4h 11m
American Airlines
Tue 2/1710:23 am
MSY
-
FLO
1 stop5h 58m
American Airlines
Deal found 2/3$617

Find flight deals from Florence to Louisiana

Keep the following information in mind while searching for Florence to Louisiana flight deals. Data was last updated February 5, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$481
(American Airlines)
Provider with most accurate pricing for Florence-New Orleans Louis Armstrong flight deals.
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Provider most trusted by Cheapflights users for Florence-New Orleans Louis Armstrong flights.
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From Florence to Louisiana
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to Louisiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 5, 2026.
Use the filters below to find and compare flights from Florence to Louisiana that are best for you.

Fly from

Florence

Fly to

Louisiana

Route

Depart

Return

Price

FlorenceNew Orleans

FLO - MSY

FLOMSY

Florence

Wed 2/25

5:58 pm-10:56 pm

1 stop5h 58m

New Orleans Louis Armstrong

Sat 2/28

7:00 am-5:50 pm

2 stops9h 50m

$494

FlorenceNew Orleans

FLO - MSY

FLOMSY

Florence

Sat 3/21

6:25 pm-11:59 pm

1 stop6h 34m

New Orleans Louis Armstrong

Mon 3/23

10:49 am-5:50 pm

1 stop6h 01m

$540

FlorenceNew Orleans

FLO - MSY

FLOMSY

Florence

Fri 3/20

6:20 pm-11:59 pm

1 stop6h 39m

New Orleans Louis Armstrong

Mon 3/23

6:43 pm-11:57 pm

1 stop4h 14m

$571

FlorenceNew Orleans

FLO - MSY

FLOMSY

Florence

Sat 3/21

5:16 am-8:27 am

1 stop4h 11m

New Orleans Louis Armstrong

Sun 3/22

6:43 pm-11:57 pm

1 stop4h 14m

$582

FlorenceNew Orleans

FLO - MSY

FLOMSY

Florence

Fri 3/20

6:20 pm-11:59 pm

1 stop6h 39m

New Orleans Louis Armstrong

Sun 3/22

6:43 pm-11:57 pm

1 stop4h 14m

$613

FlorenceNew Orleans

FLO - MSY

FLOMSY

Florence

Wed 2/18

6:15 am-11:36 am

1 stop6h 21m

New Orleans Louis Armstrong

Sun 2/22

6:43 pm-11:57 pm

1 stop4h 14m

$643

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/3

Best time to book a flight from Florence to Louisiana

Have a flexible travel schedule? Discover the best time to fly to Louisiana from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to Louisiana

What is the cheapest month to book a flight from Florence, South Carolina to Louisiana?

Currently, June is the cheapest month in which you can book a flight from Florence, South Carolina to Louisiana (average of $76). Flying from Florence, South Carolina to Louisiana in October is currently the most expensive (average of $124). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Florence to Louisiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Florence to Louisiana?

    If you book a flight to Louisiana from Florence, you will be flying from Florence, which is the city’s only airport. Florence (FLO) is located 2.3 mi from the center of Florence.

  • How long is the flight from Florence, South Carolina to Louisiana?

    For as low as $494, American Airlines can have you in Louisiana from Florence, South Carolina in 5h 58m. Florence, South Carolina and Louisiana are separated by a distance of 680 mi.

  • Can I find deals for flights from Florence to Louisiana that include hotel bookings?

    Yes. In addition to deals on Florence to Louisiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to Louisiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Louisiana.

  • Can I find deals for business class flights from Florence to Louisiana?

    Yes. Cheapflights offers flight deals from Florence to Louisiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florence, South Carolina to Louisiana?

    Currently, June is the cheapest month in which you can book a flight from Florence, South Carolina to Louisiana (average of $76). Flying from Florence, South Carolina to Louisiana in October is currently the most expensive (average of $124). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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