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$475+ Cheap flights from Florence, SC to Lexington (FLO - LEX)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/24. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — LEX
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Florence to Lexington

Discover tips and strategies to find the most affordable flight options for your journey from Florence (FLO) to Lexington (LEX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2025.

Round-trip from

$475
(American Airlines)
From Florence to Lexington Blue Grass
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Find flight deals from Florence to Lexington

Cheapest flights from Florence to Lexington
Explore the most affordable flight options available from Florence to Lexington. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/243:19 pmFLO - LEX
1 stop3h 21mAmerican Airlines
Sun 10/266:40 amLEX - FLO
1 stop4h 06mAmerican Airlines
Deal found 9/15$475

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to Lexington that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Florence to Lexington that are best for you.

Fly from

Florence

Fly to

Lexington

Route

Depart

Return

Price

FlorenceLexington

FLO - LEX

FLOLEX

Florence

Sat 3/7

2:33 pm-7:32 pm

1 stop4h 59m

Lexington Blue Grass

Wed 3/11

6:08 pm-11:38 pm

1 stop5h 30m

$475

FlorenceLexington

FLO - LEX

FLOLEX

Florence

Fri 10/24

3:19 pm-6:40 pm

1 stop3h 21m

Lexington Blue Grass

Sun 10/26

6:40 am-10:46 am

1 stop4h 06m

$475

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Best time to book a flight from Florence to Lexington

Have a flexible travel schedule? Discover the best time to fly to Lexington from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to Lexington

What is the cheapest month to book a flight from Florence, South Carolina to Lexington?

Currently, August is the cheapest month in which you can book a flight from Florence, South Carolina to Lexington (average of $303). Flying from Florence, South Carolina to Lexington in April is currently the most expensive (average of $390). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Florence to Lexington. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Florence, South Carolina to Lexington?

    Departing from Florence, South Carolina to Lexington will take you 4h 59m. The distance between Florence, South Carolina and Lexington is about 381 mi.

  • Can I find deals for flights from Florence to Lexington that include hotel bookings?

    Yes. In addition to deals on Florence to Lexington flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to Lexington?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Lexington.

  • Can I find deals for business class flights from Florence to Lexington?

    Yes. Cheapflights offers flight deals from Florence to Lexington by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florence, South Carolina to Lexington?

    Currently, August is the cheapest month in which you can book a flight from Florence, South Carolina to Lexington (average of $303). Flying from Florence, South Carolina to Lexington in April is currently the most expensive (average of $390). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Lexington?

Book flights to Lexington if you plan to visit one of these locations
Georgetown
Berea
Frankfort

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