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La Crosse

$257+ Cheap flights from Ohio to La Crosse (LSE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/4. Fares are subject to change and may not be available on all flights or dates of travel.
CVG — LSE
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Ohio to La Crosse

Cheapest flights from Ohio to La Crosse
Explore the most affordable flight options available from Ohio to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/286:30 am
CLE
-
LSE
1 stop5h 32m
American Airlines
Sun 4/511:35 am
LSE
-
CLE
1 stop5h 49m
American Airlines
Deal found 1/27$461
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/46:44 am
CLE
-
LSE
1 stop5h 23m
American Airlines
Sat 2/2811:27 am
LSE
-
CLE
1 stop4h 41m
American Airlines
Deal found 1/28$464
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1012:35 pm
DAY
-
LSE
1 stop6h 27m
American Airlines
Sun 4/126:00 am
LSE
-
DAY
1 stop4h 59m
American Airlines
Deal found 1/28$488
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/65:48 pm
CLE
-
LSE
1 stop6h 48m
American Airlines
Sun 3/811:35 am
LSE
-
CLE
1 stop4h 28m
American Airlines
Deal found 1/26$488
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/261:02 pm
DTW
-
LSE
1 stop5h 57m
American Airlines
Thu 3/55:20 am
LSE
-
DTW
1 stop3h 36m
American Airlines
Deal found 1/27$488
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/125:45 am
DTW
-
LSE
1 stop6h 16m
American Airlines
Sat 2/145:20 am
LSE
-
DTW
1 stop6h 12m
American Airlines
Deal found 1/27$537
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/3112:05 pm
CVG
-
LSE
1 stop5h 11m
American Airlines
Mon 2/25:08 pm
LSE
-
CVG
1 stop3h 52m
American Airlines
Deal found 1/27$537
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1111:00 am
CLE
-
LSE
1 stop6h 16m
American Airlines
Sun 2/1511:31 am
LSE
-
CLE
1 stop6h 02m
American Airlines
Deal found 1/27$572
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/43:29 pm
CLE
-
LSE
1 stop3h 30m
American Airlines
Fri 3/66:29 pm
LSE
-
CLE
1 stop19h 08m
American Airlines
Deal found 1/27$741
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/175:45 am
DTW
-
LSE
1 stop4h 33m
American Airlines
Fri 2/206:29 pm
LSE
-
DTW
1 stop14h 27m
American Airlines
Deal found 1/27$758
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/212:52 pm
DTW
-
LSE
1 stop5h 03m
American Airlines
Thu 6/411:31 am
LSE
-
DTW
1 stop3h 56m
American Airlines
Deal found 1/27$811

Find flight deals from Ohio to La Crosse

Keep the following information in mind while searching for Ohio to La Crosse flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$461
(American Airlines)

One-way from

$257
(American Airlines)
Provider with most accurate pricing for Cleveland Hopkins Intl-La Crosse flight deals.
Search Deals
Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-La Crosse flights.
Search Deals
From Ohio to La Crosse
Search Deals
One-way flight from Ohio to La Crosse
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Ohio to La Crosse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Ohio to La Crosse that are best for you.

Fly from

Ohio

Fly to

La Crosse

Route

Depart

Return

Price

ClevelandLa Crosse

CLE - LSE

CLELSE

Cleveland Hopkins Intl

Sat 3/28

6:30 am-11:02 am

1 stop5h 32m

La Crosse

Sun 4/5

11:35 am-6:24 pm

1 stop5h 49m

$461

DaytonLa Crosse

DAY - LSE

DAYLSE

Dayton

Fri 4/10

12:35 pm-6:02 pm

1 stop6h 27m

La Crosse

Sun 4/12

6:00 am-11:59 am

1 stop4h 59m

$488

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Thu 2/26

1:02 pm-5:59 pm

1 stop5h 57m

La Crosse

Thu 3/5

5:20 am-9:56 am

1 stop3h 36m

$488

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Thu 2/12

5:45 am-11:01 am

1 stop6h 16m

La Crosse

Sat 2/14

5:20 am-12:32 pm

1 stop6h 12m

$537

CincinnatiLa Crosse

CVG - LSE

CVGLSE

Cincinnati Cinci./N. Kentucky

Wed 2/11

12:05 pm-4:16 pm

1 stop5h 11m

La Crosse

Sun 2/15

6:29 pm-11:25 pm

1 stop3h 56m

$537

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Wed 2/11

11:30 am-10:16 pm

2 stops11h 46m

La Crosse

Sun 2/15

5:20 am-9:56 am

1 stop3h 36m

$543

ClevelandLa Crosse

CLE - LSE

CLELSE

Cleveland Hopkins Intl

Wed 2/11

11:00 am-4:16 pm

1 stop6h 16m

La Crosse

Sun 2/15

11:31 am-6:33 pm

1 stop6h 02m

$572

ClevelandLa Crosse

CLE - LSE

CLELSE

Cleveland Hopkins Intl

Fri 3/6

8:04 am-5:59 pm

2 stops10h 55m

La Crosse

Sun 3/8

6:29 pm-12:34 am

1 stop5h 05m

$575

ClevelandLa Crosse

CLE - LSE

CLELSE

Cleveland Hopkins Intl

Wed 3/4

3:29 pm-5:59 pm

1 stop3h 30m

La Crosse

Fri 3/6

6:29 pm-2:37 pm

1 stop19h 08m

$741

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Tue 2/17

5:45 am-9:18 am

1 stop4h 33m

La Crosse

Fri 2/20

6:29 pm-9:56 am

1 stop14h 27m

$758

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 13 results
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Best time to book a flight from Ohio to La Crosse

Have a flexible travel schedule? Discover the best time to fly to La Crosse from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to La Crosse

What is the cheapest month to book a flight from Ohio to La Crosse?

Currently, June is the cheapest month in which you can book a flight from Ohio to La Crosse (average of $114). Flying from Ohio to La Crosse in March is currently the most expensive (average of $454). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Ohio to La Crosse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to La Crosse from Ohio?

    Most people fly into La Crosse (LSE) if they book a flight to La Crosse from Ohio. La Crosse is conveniently located just 5.4 mi from La Crosse’s city center.

  • How long is the flight from Ohio to La Crosse?

    There are many flights that can get you from Ohio to La Crosse in 5h 32m. Fly via American Airlines to get the fastest option. There are 507 mi between Ohio and La Crosse.

  • What are the most popular routes from Ohio to La Crosse?

    The most popular flight routes from Ohio to La Crosse are Detroit Metropolitan Wayne County - La Crosse, Cleveland Hopkins Intl - La Crosse and Cincinnati Cinci./N. Kentucky - La Crosse.

  • Can I find deals for flights from Ohio to La Crosse that include hotel bookings?

    Yes. In addition to deals on Ohio to La Crosse flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to La Crosse?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to La Crosse.

  • Can I find deals for business class flights from Ohio to La Crosse?

    Yes. Cheapflights offers flight deals from Ohio to La Crosse by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ohio to La Crosse?

    Currently, June is the cheapest month in which you can book a flight from Ohio to La Crosse (average of $114). Flying from Ohio to La Crosse in March is currently the most expensive (average of $454). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near La Crosse?

Book flights to La Crosse if you plan to visit one of these locations
Decorah
Winona

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See prices for flight routes from nearby airports that may be better suited for you.
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