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La Crosse

$352+ Cheap flights from Ohio to La Crosse (LSE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/11. Fares are subject to change and may not be available on all flights or dates of travel.
CVG — LSE
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Ohio to La Crosse

Keep the following information in mind while searching for Ohio to La Crosse flight deals. Data was last updated September 11, 2025.

Round-trip from

$414
(American Airlines)

One-way from

$352
(American Airlines)
From Ohio to La Crosse
Search Deals
One-way flight from Ohio to La Crosse
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Find flight deals from Ohio to La Crosse

Cheapest flights from Ohio to La Crosse
Explore the most affordable flight options available from Ohio to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/87:03 pmDTW - LSE
1 stop5h 46mAmerican Airlines
Tue 11/114:45 pmLSE - DTW
1 stop5h 36mAmerican Airlines
Deal found 9/10$414
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/167:18 pmDTW - LSE
1 stop3h 50mAmerican Airlines
Sat 9/206:00 amLSE - DTW
1 stop4h 54mAmerican Airlines
Deal found 9/9$434
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/512:42 pmDAY - LSE
1 stop6h 27mAmerican Airlines
Sun 10/126:15 pmLSE - DAY
1 stop4h 44mAmerican Airlines
Deal found 9/11$494
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/266:05 amCVG - LSE
1 stop4h 34mAmerican Airlines
Tue 9/306:00 amLSE - CVG
1 stop5h 26mAmerican Airlines
Deal found 9/11$496
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/255:43 amDTW - LSE
1 stop4h 56mAmerican Airlines
Mon 9/296:39 pmLSE - DTW
1 stop3h 42mAmerican Airlines
Deal found 9/10$520
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/27:00 amCVG - LSE
1 stop3h 39mAmerican Airlines
Thu 10/96:15 pmLSE - CVG
1 stop3h 51mAmerican Airlines
Deal found 9/11$520
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/311:30 amDTW - LSE
2 stops7h 21mAmerican Airlines
Sun 10/56:00 amLSE - DTW
2 stops8h 18mAmerican Airlines
Deal found 9/10$626
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/197:00 amCVG - LSE
1 stop3h 39mAmerican Airlines
Fri 9/196:30 pmLSE - CVG
1 stop3h 38mAmerican Airlines
Deal found 9/11$912
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/207:00 amCVG - LSE
1 stop3h 39mAmerican Airlines
Sat 9/206:30 pmLSE - CVG
1 stop3h 42mAmerican Airlines
Deal found 9/11$943

Cheapflights Fare Finder

 
Customize your flight search to find flights from Ohio to La Crosse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Ohio to La Crosse that are best for you.

Fly from

Ohio

Fly to

La Crosse

Route

Depart

Return

Price

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Sat 11/8

7:03 pm-11:49 pm

1 stop5h 46m

La Crosse

Tue 11/11

4:45 pm-11:21 pm

1 stop5h 36m

$414

DaytonLa Crosse

DAY - LSE

DAYLSE

Dayton

Sun 10/5

12:42 pm-6:09 pm

1 stop6h 27m

La Crosse

Sun 10/12

6:15 pm-11:59 pm

1 stop4h 44m

$494

CincinnatiLa Crosse

CVG - LSE

CVGLSE

Cincinnati Cinci./N. Kentucky

Fri 9/26

6:05 am-9:39 am

1 stop4h 34m

La Crosse

Tue 9/30

6:00 am-12:26 pm

1 stop5h 26m

$496

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Fri 10/3

7:17 pm-10:08 pm

1 stop3h 51m

La Crosse

Sun 10/5

6:00 am-12:34 pm

1 stop5h 34m

$520

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Thu 9/25

5:43 am-9:39 am

1 stop4h 56m

La Crosse

Mon 9/29

6:39 pm-11:21 pm

1 stop3h 42m

$520

CincinnatiLa Crosse

CVG - LSE

CVGLSE

Cincinnati Cinci./N. Kentucky

Thu 10/2

7:00 am-9:39 am

1 stop3h 39m

La Crosse

Thu 10/9

6:15 pm-11:06 pm

1 stop3h 51m

$520

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Sat 10/11

7:00 am-10:24 am

1 stop4h 24m

$352

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Best time to book a flight from Ohio to La Crosse

Have a flexible travel schedule? Discover the best time to fly to La Crosse from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to La Crosse
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Ohio to La Crosse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to La Crosse from Ohio?

    Most people fly into La Crosse (LSE) if they book a flight to La Crosse from Ohio. La Crosse is conveniently located just 5.4 mi from La Crosse’s city center.

  • How long is the flight from Ohio to La Crosse?

    There are many flights that can get you from Ohio to La Crosse in 5h 46m. Fly via American Airlines to get the fastest option. There are 415 mi between Ohio and La Crosse.

  • What are the most popular routes from Ohio to La Crosse?

    The most popular flight routes from Ohio to La Crosse are Detroit Metropolitan Wayne County - La Crosse, Cincinnati Cinci./N. Kentucky - La Crosse and Cleveland Hopkins Intl - La Crosse.

  • Can I find deals for flights from Ohio to La Crosse that include hotel bookings?

    Yes. In addition to deals on Ohio to La Crosse flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to La Crosse?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to La Crosse.

  • Can I find deals for business class flights from Ohio to La Crosse?

    Yes. Cheapflights offers flight deals from Ohio to La Crosse by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near La Crosse?

Book flights to La Crosse if you plan to visit one of these locations
Winona
Decorah

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