$344+ Cheap flights from Detroit to La Crosse (DTT - LSE)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/31. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — LSE
Oct 20 — Oct 271
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Detroit to La Crosse with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Detroit to La Crosse
Cheapest
Best
Last-minute
One-way
Cheapest flights from Detroit to La CrosseExplore the most affordable flight options available from Detroit to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 20, 2026.
Explore the most affordable flight options available from Detroit to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 20, 2026.
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:42 am -
1 stop18h 36m
Mon 11/96:52 pm -
1 stop13h 35m
Deal found 9/18![American Airlines logo]()
$461
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/228:21 am -
1 stop4h 01m
Tue 9/295:22 pm -
1 stop5h 12m
Deal found 9/18![American Airlines logo]()
$528
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:00 am -
1 stop14h 16m
Sun 10/411:06 am -
1 stop23h 29m
Deal found 9/19![Multiple Airlines logo]()
$530
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/188:47 pm -
1 stop4h 33m
Thu 9/245:22 pm -
1 stop5h 12m
Deal found 9/16![American Airlines logo]()
$630
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/110:21 am -
1 stop7h 31m
Mon 10/56:55 pm -
1 stop20h 14m
Deal found 9/16![American Airlines logo]()
$679
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/32:51 pm -
2 stops10h 29m
Wed 10/77:04 am -
2 stops11h 11m
Deal found 9/18![American Airlines logo]()
$701
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/28:47 pm -
1 stop4h 33m
Sun 10/45:53 am -
2 stops8h 58m
Deal found 9/16![American Airlines logo]()
$724
Best flights from Detroit to La CrosseDiscover carefully curated flight deals from Detroit to La Crosse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 20, 2026.
Discover carefully curated flight deals from Detroit to La Crosse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 20, 2026.
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:42 am -
1 stop18h 36m
Mon 11/96:52 pm -
1 stop13h 35m
Deal found 9/18![American Airlines logo]()
$461
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:00 am -
1 stop14h 16m
Sun 10/411:06 am -
1 stop23h 29m
Deal found 9/19![Multiple Airlines logo]()
$530
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:36 am -
1 stop5h 46m
Wed 10/77:04 am -
2 stops11h 11m
Deal found 9/18![American Airlines logo]()
$566
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/28:47 pm -
1 stop4h 33m
Sun 10/45:53 am -
2 stops8h 58m
Deal found 9/16![American Airlines logo]()
$724
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:30 am -
2 stops10h 22m
Mon 10/512:23 pm -
1 stop6h 42m
Deal found 9/16![American Airlines logo]()
$789
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:36 am -
1 stop5h 46m
Tue 9/295:53 am -
1 stop5h 29m
Deal found 9/17![American Airlines logo]()
$973
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:36 am -
1 stop5h 46m
Thu 10/87:04 am -
1 stop4h 56m
Deal found 9/19![American Airlines logo]()
$998
Last-minute flights from Detroit to La CrosseDiscover last-minute flight deals from Detroit to La Crosse. Data last updated September 20, 2026 and is based on user searches.
Discover last-minute flight deals from Detroit to La Crosse. Data last updated September 20, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/188:47 pm -
1 stop4h 33m
Thu 9/245:22 pm -
1 stop5h 12m
Deal found 9/16![American Airlines logo]()
$630
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/228:21 am -
1 stop4h 01m
Tue 9/295:22 pm -
1 stop5h 12m
Deal found 9/18![American Airlines logo]()
$528
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:36 am -
1 stop5h 46m
Tue 9/295:53 am -
1 stop5h 29m
Deal found 9/17![American Airlines logo]()
$973
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/110:21 am -
1 stop7h 31m
Mon 10/56:55 pm -
1 stop20h 14m
Deal found 9/16![American Airlines logo]()
$679
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:00 am -
1 stop14h 16m
Sun 10/411:06 am -
1 stop23h 29m
Deal found 9/19![Multiple Airlines logo]()
$530
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/28:47 pm -
1 stop4h 33m
Sun 10/45:53 am -
2 stops8h 58m
Deal found 9/16![American Airlines logo]()
$724
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/32:51 pm -
2 stops10h 29m
Wed 10/77:04 am -
2 stops11h 11m
Deal found 9/18![American Airlines logo]()
$701
One-way flights from Detroit to La CrosseSearch for one-way flight options from Detroit to La Crosse. Find affordable one-way fares based on user searches. Data last updated September 20, 2026.
Search for one-way flight options from Detroit to La Crosse. Find affordable one-way fares based on user searches. Data last updated September 20, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:00 am -
3 stops36h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$344
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/314:46 pm -
1 stop21h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![American Airlines logo]()
$388
Find flight deals from Detroit to La Crosse
Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTT) to La Crosse (LSE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 20, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $461 (American Airlines) |
One-way from | $344 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to La Crosse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 20, 2026.
Use the filters below to find and compare flights from Detroit to La Crosse that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitLa Crosse
DTW Detroit Metropolitan Wayne County - LSE La Crosse
DTWLSE
Detroit Metropolitan Wayne County
Sat 10/31
7:00 am-6:27 pm
3 stops36h 27m
La Crosse
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$344
DetroitLa Crosse
DTW Detroit Metropolitan Wayne County - LSE La Crosse
DTWLSE
Detroit Metropolitan Wayne County
Sat 10/31
4:46 pm-12:53 pm
1 stop21h 07m
La Crosse
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$388
DetroitLa Crosse
DTW Detroit Metropolitan Wayne County - LSE La Crosse
DTWLSE
Detroit Metropolitan Wayne County
Mon 11/2
6:42 am-12:18 am
1 stop18h 36m
La Crosse
Mon 11/9
6:52 pm-9:27 am
1 stop13h 35m
$461
DetroitLa Crosse
DTW Detroit Metropolitan Wayne County - LSE La Crosse
DTWLSE
Detroit Metropolitan Wayne County
Fri 10/2
6:00 am-7:16 pm
1 stop14h 16m
La Crosse
Sun 10/4
11:06 am-11:35 am
1 stop23h 29m
$530
DetroitLa Crosse
DTW Detroit Metropolitan Wayne County - LSE La Crosse
DTWLSE
Detroit Metropolitan Wayne County
Sat 10/3
6:36 am-11:22 am
1 stop5h 46m
La Crosse
Wed 10/7
7:04 am-7:15 pm
2 stops11h 11m
$566
DetroitLa Crosse
DTW Detroit Metropolitan Wayne County - LSE La Crosse
DTWLSE
Detroit Metropolitan Wayne County
Fri 10/2
8:47 pm-12:20 am
1 stop4h 33m
La Crosse
Sun 10/4
5:53 am-3:51 pm
2 stops8h 58m
$724
DetroitLa Crosse
DTW Detroit Metropolitan Wayne County - LSE La Crosse
DTWLSE
Detroit Metropolitan Wayne County
Thu 10/1
7:30 am-4:52 pm
2 stops10h 22m
La Crosse
Mon 10/5
12:23 pm-8:05 pm
1 stop6h 42m
$789
DetroitLa Crosse
DTW Detroit Metropolitan Wayne County - LSE La Crosse
DTWLSE
Detroit Metropolitan Wayne County
Mon 9/28
6:36 am-11:22 am
1 stop5h 46m
La Crosse
Tue 9/29
5:53 am-12:22 pm
1 stop5h 29m
$973
Quickest round-trip
DetroitLa Crosse
DTW Detroit Metropolitan Wayne County - LSE La Crosse
DTWLSE
Detroit Metropolitan Wayne County
Sun 10/4
6:36 am-11:22 am
1 stop5h 46m
La Crosse
Thu 10/8
7:04 am-1:00 pm
1 stop4h 56m
$998
Sorted by cheapest first
Compare providers for flights from Detroit to La Crosse
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to La Crosse in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Detroit-La Crosse flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit-La Crosse flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit-La Crosse flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Detroit-La Crosse flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit-La Crosse flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Detroit to La Crosse
Have a flexible travel schedule? Discover the best time to fly to La Crosse from Detroit with our price prediction graph.
DTT-LSE
DTW-LSE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Detroit to La Crosse
DTT-LSE
DTW-LSE
No data available for this route at this time. Please check back soon.
Related info for your journey
Find useful and relevant information for your journey from Detroit to La Crosse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near La Crosse?
Book flights to La Crosse if you plan to visit one of these locationsDecorah
Winona
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
La Crosse flight routes
Other flight options
Other flights from Detroit
Popular flights
Top destinations