$268+ Cheap flights from Detroit to La Crosse (DTT - LSE)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/24. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — LSE
Apr 10 — Apr 171
Round-trip
1 adult, Economy
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Find cheap flights from Detroit to La Crosse with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Detroit to La Crosse
Cheapest
Best
Last-minute
One-way
Cheapest flights from Detroit to La CrosseExplore the most affordable flight options available from Detroit to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 11, 2026.
Explore the most affordable flight options available from Detroit to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 11, 2026.
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:45 am
DTW
- LSE
1 stop4h 33m
American Airlines
Sat 3/285:09 am
LSE
- DTW
1 stop3h 47m
American Airlines
Deal found 3/8![American Airlines logo]()
$268
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/255:45 am
DTW
- LSE
1 stop6h 16m
American Airlines
Sun 3/295:09 am
LSE
- DTW
1 stop6h 45m
American Airlines
Deal found 3/10![American Airlines logo]()
$288
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/28:55 pm
DTW
- LSE
1 stop4h 11m
American Airlines
Thu 6/411:52 am
LSE
- DTW
1 stop4h 07m
American Airlines
Deal found 3/9![American Airlines logo]()
$482
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:30 am
DTW
- LSE
1 stop18h 48m
American Airlines
Sun 8/96:37 pm
LSE
- DTW
1 stop3h 47m
American Airlines
Deal found 3/7![American Airlines logo]()
$550
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/305:45 am
DTW
- LSE
1 stop6h 16m
American Airlines
Fri 4/36:29 pm
LSE
- DTW
1 stop5h 02m
American Airlines
Deal found 3/11![American Airlines logo]()
$556
Best flights from Detroit to La CrosseDiscover carefully curated flight deals from Detroit to La Crosse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 11, 2026.
Discover carefully curated flight deals from Detroit to La Crosse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 11, 2026.
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/255:45 am
DTW
- LSE
1 stop6h 16m
American Airlines
Sun 3/295:09 am
LSE
- DTW
1 stop6h 45m
American Airlines
Deal found 3/10![American Airlines logo]()
$288
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/241:06 pm
DTW
- LSE
2 stops11h 30m
American Airlines
Sat 3/285:09 am
LSE
- DTW
1 stop6h 23m
American Airlines
Deal found 3/8![American Airlines logo]()
$354
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/28:55 pm
DTW
- LSE
1 stop4h 11m
American Airlines
Thu 6/45:34 pm
LSE
- DTW
1 stop5h 05m
American Airlines
Deal found 3/7![American Airlines logo]()
$482
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/305:45 am
DTW
- LSE
1 stop6h 16m
American Airlines
Fri 4/36:29 pm
LSE
- DTW
1 stop5h 02m
American Airlines
Deal found 3/11![American Airlines logo]()
$556
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/238:20 am
DTW
- LSE
1 stop3h 41m
American Airlines
Fri 3/275:09 am
LSE
- DTW
1 stop6h 23m
American Airlines
Deal found 3/11![American Airlines logo]()
$641
Last-minute flights from Detroit to La CrosseDiscover last-minute flight deals from Detroit to La Crosse. Data last updated March 11, 2026 and is based on user searches.
Discover last-minute flight deals from Detroit to La Crosse. Data last updated March 11, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/238:20 am
DTW
- LSE
1 stop3h 41m
American Airlines
Fri 3/275:09 am
LSE
- DTW
1 stop6h 23m
American Airlines
Deal found 3/11![American Airlines logo]()
$641
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:45 am
DTW
- LSE
1 stop4h 33m
American Airlines
Sat 3/285:09 am
LSE
- DTW
1 stop3h 47m
American Airlines
Deal found 3/8![American Airlines logo]()
$268
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/255:45 am
DTW
- LSE
1 stop6h 16m
American Airlines
Sun 3/295:09 am
LSE
- DTW
1 stop6h 45m
American Airlines
Deal found 3/10![American Airlines logo]()
$288
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/305:45 am
DTW
- LSE
1 stop6h 16m
American Airlines
Fri 4/36:29 pm
LSE
- DTW
1 stop5h 02m
American Airlines
Deal found 3/11![American Airlines logo]()
$556
One-way flights from Detroit to La CrosseSearch for one-way flight options from Detroit to La Crosse. Find affordable one-way fares based on user searches. Data last updated March 11, 2026.
Search for one-way flight options from Detroit to La Crosse. Find affordable one-way fares based on user searches. Data last updated March 11, 2026.
This KAYAK deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/172:06 pm
DTW
- LSE
1 stop4h 53m
American Airlines
Deal found 3/11![American Airlines logo]()
$296
Find flight deals from Detroit to La Crosse
Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTT) to La Crosse (LSE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $268 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to La Crosse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 11, 2026.
Use the filters below to find and compare flights from Detroit to La Crosse that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitLa Crosse
DTW - LSE
DTWLSE
Detroit Metropolitan Wayne County
Wed 3/25
5:45 am-11:01 am
1 stop6h 16m
La Crosse
Sun 3/29
5:09 am-12:54 pm
1 stop6h 45m
$288
DetroitLa Crosse
DTW - LSE
DTWLSE
Detroit Metropolitan Wayne County
Tue 3/24
1:06 pm-11:36 pm
2 stops11h 30m
La Crosse
Sat 3/28
5:09 am-12:32 pm
1 stop6h 23m
$354
Quickest round-trip
DetroitLa Crosse
DTW - LSE
DTWLSE
Detroit Metropolitan Wayne County
Tue 6/2
8:55 pm-12:06 am
1 stop4h 11m
La Crosse
Thu 6/4
5:34 pm-11:39 pm
1 stop5h 05m
$482
DetroitLa Crosse
DTW - LSE
DTWLSE
Detroit Metropolitan Wayne County
Mon 3/30
5:45 am-11:01 am
1 stop6h 16m
La Crosse
Fri 4/3
6:29 pm-12:31 am
1 stop5h 02m
$556
DetroitLa Crosse
DTW - LSE
DTWLSE
Detroit Metropolitan Wayne County
Mon 3/23
8:20 am-11:01 am
1 stop3h 41m
La Crosse
Fri 3/27
5:09 am-12:32 pm
1 stop6h 23m
$641
Cheapest one-way
Quickest one-way
DetroitLa Crosse
DTW - LSE
DTWLSE
Detroit Metropolitan Wayne County
Tue 3/17
2:06 pm-5:59 pm
1 stop4h 53m
$296
Sorted by cheapest first
Compare providers for flights from Detroit to La Crosse
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to La Crosse in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Detroit-La Crosse flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit-La Crosse flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit-La Crosse flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Detroit-La Crosse flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit-La Crosse flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Detroit to La Crosse
Have a flexible travel schedule? Discover the best time to fly to La Crosse from Detroit with our price prediction graph.
DTT-LSE
DTW-LSE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Detroit to La Crosse
DTT-LSE
DTW-LSE
No data available for this route at this time. Please check back soon.
Related info for your journey
Find useful and relevant information for your journey from Detroit to La Crosse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near La Crosse?
Book flights to La Crosse if you plan to visit one of these locationsDecorah
Winona
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Other flights to La Crosse
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Consider these flights traveling from Detroit to La Crosse.
Top airline flying from Detroit to La Crosse
Discover the top airline that operate flights from Detroit to La Crosse. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$414 | Average$468 | FlexibilityNo cancel fee | On-time71% |