What are the cheapest airlines to fly from South Dakota to Knoxville one-way?

$136 is the cheapest one-way deal found within the past few days, from Allegiant Air. You may also be able to find cheap deals on Delta and American Airlines, with prices starting from $249 and $286, respectively.

What are the most popular airlines that fly from South Dakota to Knoxville?

Consider American Airlines, Delta or United Airlines when booking your flight. These represent the most popular airlines when flying from South Dakota to Knoxville.

What is the cheapest month to fly from South Dakota to Knoxville?

Our data shows that August tends to be the cheapest month to fly to Knoxville from South Dakota. Users have commonly found prices around $402 for the month, but tickets can be as low as $212. Due to multiple factors, prepare for potentially higher prices in January.

What airport do you fly into for flights to Knoxville from South Dakota?

Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to Knoxville from South Dakota.

Can I find deals for flights from South Dakota to Knoxville that include hotel bookings?

Yes. In addition to deals on South Dakota to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from South Dakota to Knoxville?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Dakota to Knoxville.

Can I find deals for business class flights from South Dakota to Knoxville?

Yes. Cheapflights offers flight deals from South Dakota to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$136+ Flights from South Dakota to Knoxville

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Cheap flight deals from South Dakota to Knoxville

Round-trip from	$249 (American Airlines)
One-way from	$136 (Mytrip)
Popular in	January
Cheapest in	August
Average price	$494

From South Dakota to Knoxville McGhee Tyson

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One-way flight from South Dakota to Knoxville McGhee Tyson

Search Deals

Highest demand for flights based on searches. 21% potential increase in price ($111 potential increase over avg. RT price).

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Cheapest flight prices on average. 4% potential price decrease ($18 potential savings vs. average RT price).

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Average for round-trip flights in June 2025

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Find flight deals from South Dakota to Knoxville

Cheapest flights from South Dakota to Knoxville
Explore the most affordable flight options available from South Dakota to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 18, 2025.

Sat 8/95:15 pmFSD - TYS

1 stop6h 04mAmerican Airlines

Fri 8/152:23 pmTYS - FSD

1 stop7h 40mAmerican Airlines

Deal found 6/18

$249

Tue 9/235:00 pmRAP - TYS

1 stop5h 21mAmerican Airlines

Tue 9/306:12 amTYS - RAP

1 stop6h 23mAmerican Airlines

Deal found 6/17

$259

Thu 7/39:59 pmRAP - TYS

1 stop13h 39mMultiple Airlines

Mon 7/711:01 amTYS - RAP

1 stop7h 26mMultiple Airlines

Deal found 6/17

$281

Fri 7/186:16 pmFSD - TYS

1 stop4h 28mDelta

Fri 7/256:42 amTYS - FSD

1 stop4h 50mDelta

Deal found 6/16

$384

Fri 7/1811:57 amFSD - TYS

3 stops26h 05mMultiple Airlines

Fri 7/258:52 amTYS - FSD

2 stops11h 24mMultiple Airlines

Deal found 6/16

$431

Fri 8/18:00 amFSD - TYS

1 stop13h 37mUnited Airlines

Tue 8/55:46 pmTYS - FSD

1 stop5h 14mUnited Airlines

Deal found 6/16

$438

Wed 7/27:48 pmFSD - TYS

1 stop19h 41mFrontier

Sun 7/65:25 pmTYS - FSD

1 stop26h 12mFrontier

Deal found 6/16

$610

Fri 6/206:20 amRAP - TYS

1 stop5h 01mUnited Airlines

Tue 6/241:56 pmTYS - RAP

1 stop22h 25mUnited Airlines

Deal found 6/17

$653

Best flights from South Dakota to Knoxville
Discover carefully curated flight deals from South Dakota to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 18, 2025.

Sat 8/95:15 pmFSD - TYS

1 stop6h 04mAmerican Airlines

Fri 8/152:23 pmTYS - FSD

1 stop7h 40mAmerican Airlines

Deal found 6/18

$249

Thu 7/39:59 pmRAP - TYS

1 stop13h 39mMultiple Airlines

Mon 7/711:01 amTYS - RAP

1 stop7h 26mMultiple Airlines

Deal found 6/17

$281

Fri 7/186:16 pmFSD - TYS

1 stop4h 28mDelta

Fri 7/256:42 amTYS - FSD

1 stop4h 50mDelta

Deal found 6/16

$384

Fri 8/18:00 amFSD - TYS

1 stop13h 37mUnited Airlines

Tue 8/55:46 pmTYS - FSD

1 stop5h 14mUnited Airlines

Deal found 6/16

$438

Tue 9/235:00 pmRAP - TYS

1 stop5h 21mAmerican Airlines

Tue 9/306:12 amTYS - RAP

1 stop6h 23mAmerican Airlines

Deal found 6/17

$259

Wed 7/27:48 pmFSD - TYS

1 stop19h 41mFrontier

Sun 7/65:25 pmTYS - FSD

1 stop26h 12mFrontier

Deal found 6/16

$610

Fri 7/1811:57 amFSD - TYS

2 stops26h 05mMultiple Airlines

Fri 7/258:52 amTYS - FSD

2 stops11h 24mMultiple Airlines

Deal found 6/16

$394

Thu 7/35:30 amRAP - TYS

1 stop7h 34mUnited Airlines

Mon 7/75:46 pmTYS - RAP

3 stops29h 01mUnited Airlines

Deal found 6/17

$654

Last-minute flights from South Dakota to Knoxville
Discover last-minute flight deals from South Dakota to Knoxville. Data last updated June 18, 2025 and is based on user searches.

Fri 6/206:20 amRAP - TYS

1 stop5h 01mUnited Airlines

Tue 6/241:56 pmTYS - RAP

1 stop22h 25mUnited Airlines

Deal found 6/17

$653

Wed 6/257:23 amFSD - TYS

1 stop4h 59mAmerican Airlines

Tue 7/11:06 pmTYS - FSD

1 stop5h 20mAmerican Airlines

Deal found 6/17

$394

Wed 6/2511:18 amRAP - TYS

1 stop5h 43mAmerican Airlines

Sat 6/281:06 pmTYS - RAP

1 stop6h 38mAmerican Airlines

Deal found 6/16

$479

Wed 6/255:41 pmRAP - TYS

2 stops25h 26mMultiple Airlines

Sun 6/296:00 amTYS - RAP

2 stops17h 12mMultiple Airlines

Deal found 6/16

$548

Wed 6/251:44 pmFSD - TYS

3 stops29h 30mMultiple Airlines

Tue 7/11:18 pmTYS - FSD

3 stops26h 08mMultiple Airlines

Deal found 6/17

$632

Wed 6/253:10 pmFSD - TYS

1 stop6h 30mUnited Airlines

Tue 7/15:45 amTYS - FSD

2 stops17h 15mUnited Airlines

Deal found 6/17

$667

Wed 6/256:20 amRAP - TYS

2 stops26h 07mUnited Airlines

Sun 6/297:00 amTYS - RAP

1 stop16h 46mUnited Airlines

Deal found 6/16

$697

Wed 7/27:48 pmFSD - TYS

1 stop19h 41mFrontier

Sun 7/65:25 pmTYS - FSD

1 stop26h 12mFrontier

Deal found 6/16

$610

Thu 7/39:59 pmRAP - TYS

1 stop13h 39mMultiple Airlines

Mon 7/711:01 amTYS - RAP

1 stop7h 26mMultiple Airlines

Deal found 6/17

$281

Tue 7/155:11 pmFSD - TYS

1 stop5h 41mAmerican Airlines

Tue 7/221:54 pmTYS - FSD

1 stop4h 34mAmerican Airlines

Deal found 6/16

$249

Fri 7/186:16 pmFSD - TYS

1 stop4h 28mDelta

Fri 7/256:42 amTYS - FSD

1 stop4h 50mDelta

Deal found 6/16

$384

Fri 7/1811:57 amFSD - TYS

3 stops26h 05mMultiple Airlines

Fri 7/258:52 amTYS - FSD

2 stops11h 24mMultiple Airlines

Deal found 6/16

$431

One-way flights from South Dakota to Knoxville
Search for one-way flight options from South Dakota to Knoxville. Find affordable one-way fares based on user searches. Data last updated June 18, 2025.

Sun 8/1710:00 pmRAP - TYS

1 stop13h 39mAllegiant Air

Deal found 6/17

$136

Sun 8/179:44 amFSD - TYS

1 stop8h 40mAllegiant Air

Deal found 6/17

$155

Sun 8/175:00 amFSD - TYS

2 stops7h 08mDelta

Deal found 6/17

$249

Wed 6/2511:18 amRAP - TYS

1 stop5h 43mAmerican Airlines

Deal found 6/16

$286

Sun 8/179:42 amRAP - TYS

2 stops10h 53mUnited Airlines

Deal found 6/17

$291

Cheapflights Fare Finder

Use the filters below to find and compare flights from South Dakota to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Sioux FallsKnoxville

FSD - TYS

FSDTYS

Sioux Falls Joe Foss Field

Sat 8/9

5:15 pm-12:19 am

1 stop6h 04m

Knoxville McGhee Tyson

Fri 8/15

2:23 pm-9:03 pm

1 stop7h 40m

$249

Rapid CityKnoxville

RAP - TYS

RAPTYS

Rapid City

Tue 9/23

5:00 pm-12:21 am

1 stop5h 21m

Knoxville McGhee Tyson

Tue 9/30

6:12 am-10:35 am

1 stop6h 23m

$259

Rapid CityKnoxville

RAP - TYS

RAPTYS

Rapid City

Thu 7/3

9:59 pm-1:38 pm

1 stop13h 39m

Knoxville McGhee Tyson

Mon 7/7

11:01 am-4:27 pm

1 stop7h 26m

$281

Sioux FallsKnoxville

FSD - TYS

FSDTYS

Sioux Falls Joe Foss Field

Fri 7/18

6:16 pm-11:44 pm

1 stop4h 28m

Knoxville McGhee Tyson

Fri 7/25

6:42 am-10:32 am

1 stop4h 50m

$384

Sioux FallsKnoxville

FSD - TYS

FSDTYS

Sioux Falls Joe Foss Field

Fri 7/18

11:57 am-3:02 pm

2 stops26h 05m

Knoxville McGhee Tyson

Fri 7/25

8:52 am-7:16 pm

2 stops11h 24m

$394

Sioux FallsKnoxville

FSD - TYS

FSDTYS

Sioux Falls Joe Foss Field

Fri 8/1

8:00 am-10:37 pm

1 stop13h 37m

Knoxville McGhee Tyson

Tue 8/5

5:46 pm-10:00 pm

1 stop5h 14m

$438

Sioux FallsKnoxville

FSD - TYS

FSDTYS

Sioux Falls Joe Foss Field

Wed 7/2

7:48 pm-4:29 pm

1 stop19h 41m

Knoxville McGhee Tyson

Sun 7/6

5:25 pm-6:37 pm

1 stop26h 12m

$610

Rapid CityKnoxville

RAP - TYS

RAPTYS

Rapid City

Thu 7/3

5:30 am-3:04 pm

1 stop7h 34m

Knoxville McGhee Tyson

Mon 7/7

5:46 pm-8:47 pm

3 stops29h 01m

$654

Rapid CityKnoxville

RAP - TYS

RAPTYS

Rapid City

Sun 8/17

10:00 pm-1:39 pm

1 stop13h 39m

$136

Sioux FallsKnoxville

FSD - TYS

FSDTYS

Sioux Falls Joe Foss Field

Sun 8/17

9:44 am-7:24 pm

1 stop8h 40m

$155

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/17

Showing 1-10 of 13 results

Best time to book a flight from South Dakota to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from South Dakota with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Dakota to Knoxville

What is the cheapest month to book a flight from South Dakota to Knoxville?

Currently, January is the cheapest month in which you can book a flight from South Dakota to Knoxville (average of $296). Flying from South Dakota to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SD to TYS?

When flying from South Dakota to Knoxville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Knoxville by month

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Read reviews from past customers who have flown Delta, United Airlines and Allegiant Air from South Dakota to Knoxville. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,964 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,964 reviews

Delta

8.0

Very good

7,964 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

United Airlines

7.4

Good

8,810 reviews

Delta

8.0

Very good

7,964 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Allegiant Air

7.3

Good

722 reviews

Delta

8.0

Very good

7,964 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,964 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Frontier

5.9

Fair

3,301 reviews

Delta

8.0

Very good

7,964 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What airport do you fly into for flights to Knoxville from South Dakota?
Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to Knoxville from South Dakota.
What are the cheapest airlines to fly from South Dakota to Knoxville one-way?
$136 is the cheapest one-way deal found within the past few days, from Allegiant Air. You may also be able to find cheap deals on Delta and American Airlines, with prices starting from $249 and $286, respectively.
Can I find deals for flights from South Dakota to Knoxville that include hotel bookings?
Yes. In addition to deals on South Dakota to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from South Dakota to Knoxville?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Dakota to Knoxville.
Can I find deals for business class flights from South Dakota to Knoxville?
Yes. Cheapflights offers flight deals from South Dakota to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from South Dakota to Knoxville?
Currently, January is the cheapest month in which you can book a flight from South Dakota to Knoxville (average of $296). Flying from South Dakota to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Morristown

Cherokee

Corbin

Oak Ridge

Alcoa

Murphy

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Top 3 airlines flying from South Dakota to Knoxville

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$221	Average$312	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$248	Average$418	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$283	Average$477	FlexibilityNo cancel fee	On-time69%

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$136+ Cheap flights from South Dakota to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/17. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from South Dakota to Knoxville with Cheapflights

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2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from South Dakota to Knoxville

Keep the following information in mind while searching for South Dakota to Knoxville flight deals. Data was last updated June 18, 2025.

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from South Dakota to Knoxville

Cheapest flights from South Dakota to KnoxvilleExplore the most affordable flight options available from South Dakota to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 18, 2025.

Explore the most affordable flight options available from South Dakota to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 18, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from South Dakota to Knoxville that are best for you.

Best time to book a flight from South Dakota to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from South Dakota with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from South Dakota to Knoxville

What is the cheapest month to book a flight from South Dakota to Knoxville?

What is the cheapest time of day to fly from SD to TYS?

Find hourly flight availability from South Dakota to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 18, 2025.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

Reviews of airlines servicing Knoxville

Read reviews from past customers who have flown Delta, United Airlines and Allegiant Air from South Dakota to Knoxville. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from South Dakota to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Knoxville from South Dakota?

What are the cheapest airlines to fly from South Dakota to Knoxville one-way?

Can I find deals for flights from South Dakota to Knoxville that include hotel bookings?

How can I find direct flights from South Dakota to Knoxville?

Can I find deals for business class flights from South Dakota to Knoxville?

What is the cheapest month to book a flight from South Dakota to Knoxville?

Traveling to a place near South Dakota?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Dakota to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from South Dakota to Knoxville

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Cheapest flights from South Dakota to Knoxville
Explore the most affordable flight options available from South Dakota to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 18, 2025.