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Knoxville

$249+ Cheap flights from South Dakota to Knoxville (TYS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/28. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — TYS
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
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Cheap flight deals from South Dakota to Knoxville

Keep the following information in mind while searching for South Dakota to Knoxville flight deals. Data was last updated May 1, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$249
(American Airlines)

Popular in

December

Cheapest in

August

Average price

$446
Provider with most accurate pricing for Sioux Falls Joe Foss Field-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Sioux Falls Joe Foss Field-Knoxville McGhee Tyson flights.
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From South Dakota to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 23% potential increase in price ($125 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($22 potential savings vs. average RT price).
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Average for round-trip flights in May 2025
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Find flight deals from South Dakota to Knoxville

Cheapest flights from South Dakota to Knoxville
Explore the most affordable flight options available from South Dakota to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/285:45 pmFSD - TYS
1 stop5h 13mAmerican Airlines
Wed 6/411:43 amTYS - FSD
1 stop4h 54mAmerican Airlines
Deal found 4/30$249
This Mytrip deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/266:55 pmFSD - TYS
1 stop25h 26mAllegiant Air
Sun 6/297:40 pmTYS - FSD
2 stops24h 33mAllegiant Air
Deal found 4/29$318
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/285:00 amFSD - TYS
2 stops7h 19mDelta
Wed 6/45:45 amTYS - FSD
2 stops7h 19mDelta
Deal found 4/30$324
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/34:39 pmRAP - TYS
1 stop5h 20mAmerican Airlines
Tue 7/86:00 amTYS - RAP
1 stop5h 55mAmerican Airlines
Deal found 4/30$384
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/2511:20 amFSD - TYS
1 stop4h 37mUnited Airlines
Sun 6/295:46 pmTYS - FSD
1 stop5h 14mUnited Airlines
Deal found 4/29$403
This Booking.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/257:48 pmFSD - TYS
1 stop19h 41mFrontier
Sun 6/295:25 pmTYS - FSD
1 stop26h 07mFrontier
Deal found 4/29$412
This Mytrip deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/251:44 pmFSD - TYS
2 stops29h 30mMultiple Airlines
Sun 6/297:40 pmTYS - FSD
2 stops24h 33mMultiple Airlines
Deal found 4/29$416
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/141:38 pmRAP - TYS
1 stop7h 27mUnited Airlines
Sat 6/215:38 pmTYS - RAP
1 stop5h 41mUnited Airlines
Deal found 4/30$439
This Mytrip deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/149:49 amRAP - TYS
2 stops33h 18mMultiple Airlines
Sat 6/216:00 amTYS - RAP
3 stops41h 12mMultiple Airlines
Deal found 4/30$546

Cheapflights Fare Finder

Customize your flight search to find flights from South Dakota to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from South Dakota to Knoxville that are best for you.

Fly from

South Dakota

Fly to

Knoxville

Route

Depart

Return

Price

Sioux FallsKnoxville

FSD - TYS

FSDTYS

Sioux Falls Joe Foss Field

Wed 5/28

5:45 pm-11:58 pm

1 stop5h 13m

Knoxville McGhee Tyson

Wed 6/4

11:43 am-3:37 pm

1 stop4h 54m

$249

Sioux FallsKnoxville

FSD - TYS

FSDTYS

Sioux Falls Joe Foss Field

Thu 6/26

6:55 pm-9:21 pm

1 stop25h 26m

Knoxville McGhee Tyson

Sun 6/29

7:40 pm-7:13 pm

2 stops24h 33m

$318

Sioux FallsKnoxville

FSD - TYS

FSDTYS

Sioux Falls Joe Foss Field

Wed 5/28

5:00 am-1:19 pm

2 stops7h 19m

Knoxville McGhee Tyson

Wed 6/4

5:45 am-12:04 pm

2 stops7h 19m

$324

Rapid CityKnoxville

RAP - TYS

RAPTYS

Rapid City

Thu 7/3

4:39 pm-11:59 pm

1 stop5h 20m

Knoxville McGhee Tyson

Tue 7/8

6:00 am-9:55 am

1 stop5h 55m

$384

Sioux FallsKnoxville

FSD - TYS

FSDTYS

Sioux Falls Joe Foss Field

Wed 6/25

11:20 am-4:57 pm

1 stop4h 37m

Knoxville McGhee Tyson

Sun 6/29

5:46 pm-10:00 pm

1 stop5h 14m

$403

Sioux FallsKnoxville

FSD - TYS

FSDTYS

Sioux Falls Joe Foss Field

Wed 6/25

7:48 pm-4:29 pm

1 stop19h 41m

Knoxville McGhee Tyson

Sun 6/29

5:25 pm-6:32 pm

1 stop26h 07m

$412

Sioux FallsKnoxville

FSD - TYS

FSDTYS

Sioux Falls Joe Foss Field

Wed 6/25

1:44 pm-8:14 pm

2 stops29h 30m

Knoxville McGhee Tyson

Sun 6/29

7:40 pm-7:13 pm

2 stops24h 33m

$416

Rapid CityKnoxville

RAP - TYS

RAPTYS

Rapid City

Sat 6/14

1:38 pm-11:05 pm

1 stop7h 27m

Knoxville McGhee Tyson

Sat 6/21

5:38 pm-9:19 pm

1 stop5h 41m

$439

Rapid CityKnoxville

RAP - TYS

RAPTYS

Rapid City

Sat 6/14

9:49 am-9:07 pm

2 stops33h 18m

Knoxville McGhee Tyson

Sat 6/21

6:00 am-9:12 pm

3 stops41h 12m

$546

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/30

Best time to book a flight from South Dakota to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from South Dakota with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Dakota to Knoxville

What is the cheapest month to book a flight from South Dakota to Knoxville?

Currently, January is the cheapest month in which you can book a flight from South Dakota to Knoxville (average of $296). Flying from South Dakota to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SD to TYS?

Find hourly flight availability from South Dakota to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

When flying from South Dakota to Knoxville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated May 1, 2025.
Read reviews from past customers who have flown Delta, United Airlines and Allegiant Air from South Dakota to Knoxville. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,934 reviews

Food

7.3

Crew

8.5

Overall

8.0

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,934 reviews
Delta
8.0
Very good
7,934 reviews

Food

7.3

Crew

8.5

Overall

8.0

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,934 reviews

Food

7.3

Crew

8.5

Overall

8.0

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Allegiant Air
7.3
Good
734 reviews
Delta
8.0
Very good
7,934 reviews

Food

7.3

Crew

8.5

Overall

8.0

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,934 reviews

Food

7.3

Crew

8.5

Overall

8.0

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Frontier
6.0
Okay
3,287 reviews
Delta
8.0
Very good
7,934 reviews

Food

7.3

Crew

8.5

Overall

8.0

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from South Dakota to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from South Dakota?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to Knoxville from South Dakota.

  • Can I find deals for flights from South Dakota to Knoxville that include hotel bookings?

    Yes. In addition to deals on South Dakota to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Dakota to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Dakota to Knoxville.

  • Can I find deals for business class flights from South Dakota to Knoxville?

    Yes. Cheapflights offers flight deals from South Dakota to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Dakota to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from South Dakota to Knoxville (average of $296). Flying from South Dakota to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near South Dakota?

Book flights to South Dakota if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Maryville
Oak Ridge
Alcoa
Murphy

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Top 3 airlines flying from South Dakota to Knoxville

Discover the top 3 airlines that operate flights from South Dakota to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$221Average$343FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$426FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$268Average$466FlexibilityNo cancel feeOn-time69%

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