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$123+ Cheap flights from South Dakota to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/13. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — TYS
Aug 12 — Aug 191
Tue 8/12
Tue 8/19
1 adult, Economy
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Cheap flight deals from South Dakota to Knoxville

Keep the following information in mind while searching for South Dakota to Knoxville flight deals. Data was last updated August 7, 2025.

Round-trip from

$217
(Mytrip)

One-way from

$123
(FlightHub)

Popular in

January

Cheapest in

September

Average price

$313
From South Dakota to Knoxville McGhee Tyson
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One-way flight from South Dakota to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 20% potential increase in price ($107 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($18 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from South Dakota to Knoxville

Cheapest flights from South Dakota to Knoxville
Explore the most affordable flight options available from South Dakota to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 7, 2025.

This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/255:05 pmFSD - TYS
1 stop6h 18mAmerican Airlines
Wed 10/296:00 amTYS - FSD
1 stop7h 45mAmerican Airlines
Deal found 8/6$249
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/251:27 pmFSD - TYS
2 stops9h 23mAmerican Airlines
Tue 10/2811:44 amTYS - FSD
2 stops10h 32mAmerican Airlines
Deal found 8/6$259
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/105:27 amFSD - TYS
1 stop6h 41mDelta
Sat 9/206:08 pmTYS - FSD
1 stop5h 54mDelta
Deal found 8/6$260
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/215:15 pmFSD - TYS
1 stop5h 38mAmerican Airlines
Mon 8/2512:03 pmTYS - FSD
2 stops10h 00mAmerican Airlines
Deal found 8/6$264
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/105:27 amFSD - TYS
1 stop6h 41mDelta
Wed 9/175:45 amTYS - FSD
2 stops9h 06mDelta
Deal found 8/6$265
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/242:32 pmFSD - TYS
2 stops8h 12mDelta
Sat 9/275:45 amTYS - FSD
2 stops7h 26mDelta
Deal found 8/6$270
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/105:33 pmFSD - TYS
1 stop5h 48mAmerican Airlines
Thu 9/182:07 pmTYS - FSD
1 stop8h 12mAmerican Airlines
Deal found 8/6$274
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/95:27 amFSD - TYS
1 stop6h 41mDelta
Thu 9/185:45 amTYS - FSD
2 stops7h 26mDelta
Deal found 8/6$279
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/215:30 amRAP - TYS
1 stop7h 45mUnited Airlines
Mon 8/254:40 pmTYS - RAP
1 stop7h 19mUnited Airlines
Deal found 8/6$284
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/95:27 amFSD - TYS
1 stop4h 15mDelta
Fri 9/196:08 pmTYS - FSD
1 stop5h 54mDelta
Deal found 8/6$294
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/174:30 pmRAP - TYS
1 stop5h 51mAmerican Airlines
Mon 1/54:25 pmTYS - RAP
1 stop5h 52mAmerican Airlines
Deal found 8/5$304
This United Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/174:35 pmRAP - TYS
2 stops15h 40mUnited Airlines
Mon 1/59:50 amTYS - RAP
2 stops10h 57mUnited Airlines
Deal found 8/5$514

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Dakota to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 7, 2025.
Use the filters below to find and compare flights from South Dakota to Knoxville that are best for you.

Fly from

South Dakota

Fly to

Knoxville

Route

Depart

Return

Price

Sioux FallsKnoxville

FSD - TYS

FSDTYS

Sioux Falls Joe Foss Field

Sat 10/25

5:05 pm-12:23 am

1 stop6h 18m

Knoxville McGhee Tyson

Wed 10/29

6:00 am-12:45 pm

1 stop7h 45m

$249

Sioux FallsKnoxville

FSD - TYS

FSDTYS

Sioux Falls Joe Foss Field

Sat 10/25

1:27 pm-11:50 pm

2 stops9h 23m

Knoxville McGhee Tyson

Tue 10/28

5:00 am-12:45 pm

2 stops8h 45m

$259

Sioux FallsKnoxville

FSD - TYS

FSDTYS

Sioux Falls Joe Foss Field

Wed 9/10

5:27 am-1:08 pm

1 stop6h 41m

Knoxville McGhee Tyson

Sat 9/20

6:08 pm-11:02 pm

1 stop5h 54m

$260

Sioux FallsKnoxville

FSD - TYS

FSDTYS

Sioux Falls Joe Foss Field

Thu 8/21

5:15 pm-11:53 pm

1 stop5h 38m

Knoxville McGhee Tyson

Mon 8/25

12:03 pm-9:03 pm

2 stops10h 00m

$264

Sioux FallsKnoxville

FSD - TYS

FSDTYS

Sioux Falls Joe Foss Field

Wed 9/10

5:27 am-1:08 pm

1 stop6h 41m

Knoxville McGhee Tyson

Wed 9/17

5:45 am-1:51 pm

2 stops9h 06m

$265

Sioux FallsKnoxville

FSD - TYS

FSDTYS

Sioux Falls Joe Foss Field

Wed 9/24

2:32 pm-11:44 pm

2 stops8h 12m

Knoxville McGhee Tyson

Sat 9/27

5:45 am-12:11 pm

2 stops7h 26m

$270

Sioux FallsKnoxville

FSD - TYS

FSDTYS

Sioux Falls Joe Foss Field

Wed 9/10

5:33 pm-12:21 am

1 stop5h 48m

Knoxville McGhee Tyson

Thu 9/18

2:07 pm-9:19 pm

1 stop8h 12m

$274

Sioux FallsKnoxville

FSD - TYS

FSDTYS

Sioux Falls Joe Foss Field

Tue 9/9

5:27 am-1:08 pm

1 stop6h 41m

Knoxville McGhee Tyson

Thu 9/18

5:45 am-12:11 pm

2 stops7h 26m

$279

Rapid CityKnoxville

RAP - TYS

RAPTYS

Rapid City

Thu 8/21

5:30 am-3:15 pm

1 stop7h 45m

Knoxville McGhee Tyson

Mon 8/25

4:40 pm-9:59 pm

1 stop7h 19m

$284

Sioux FallsKnoxville

FSD - TYS

FSDTYS

Sioux Falls Joe Foss Field

Tue 9/9

5:27 am-10:42 am

1 stop4h 15m

Knoxville McGhee Tyson

Fri 9/19

6:08 pm-11:02 pm

1 stop5h 54m

$294

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/7

Showing 1-10 of 24 results
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Best time to book a flight from South Dakota to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from South Dakota with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Dakota to Knoxville

What is the cheapest month to book a flight from South Dakota to Knoxville?

Currently, January is the cheapest month in which you can book a flight from South Dakota to Knoxville (average of $294). Flying from South Dakota to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SD to TYS?

Find hourly flight availability from South Dakota to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 7, 2025.

When flying from South Dakota to Knoxville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated August 7, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from South Dakota to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,987 reviews

Crew

8.5

Food

7.3

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,987 reviews
Delta
8.0
Very good
7,987 reviews

Crew

8.5

Food

7.3

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,916 reviews
Delta
8.0
Very good
7,987 reviews

Crew

8.5

Food

7.3

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,987 reviews

Crew

8.5

Food

7.3

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Allegiant Air
7.2
Good
701 reviews
Delta
8.0
Very good
7,987 reviews

Crew

8.5

Food

7.3

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Frontier
5.9
Fair
3,230 reviews
Delta
8.0
Very good
7,987 reviews

Crew

8.5

Food

7.3

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from South Dakota to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from South Dakota?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to Knoxville from South Dakota.

  • What are the cheapest airlines to fly from South Dakota to Knoxville one-way?

    $123 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on Allegiant Air and United Airlines, with prices starting from $135 and $171, respectively.

  • Can I find deals for flights from South Dakota to Knoxville that include hotel bookings?

    Yes. In addition to deals on South Dakota to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Dakota to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Dakota to Knoxville.

  • Can I find deals for business class flights from South Dakota to Knoxville?

    Yes. Cheapflights offers flight deals from South Dakota to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Dakota to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from South Dakota to Knoxville (average of $294). Flying from South Dakota to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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Alternative routes for South Dakota to Knoxville

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Top 3 airlines flying from South Dakota to Knoxville

Discover the top 3 airlines that operate flights from South Dakota to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 7, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$221Average$293FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$426FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$268Average$433FlexibilityNo cancel feeOn-time69%

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