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$463+ Cheap flights from Sioux City to Knoxville (SUX - TYS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/2. Fares are subject to change and may not be available on all flights or dates of travel.
SUX — TYS
Aug 23 — Aug 301
Sat 8/23
Sat 8/30
1 adult, Economy
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Cheap flight deals from Sioux City to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Sioux City (SUX) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 18, 2025.

Round-trip from

$463
(United Airlines)
From Sioux City Sioux Gateway to Knoxville McGhee Tyson
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Cheapest flights from Sioux City to Knoxville
Explore the most affordable flight options available from Sioux City to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2025.

This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/26:48 pmSUX - TYS
2 stops22h 22mUnited Airlines
Sat 9/67:20 amTYS - SUX
2 stops11h 53mUnited Airlines
Deal found 8/18$463

Cheapflights Fare Finder

 
Customize your flight search to find flights from Sioux City to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2025.
Use the filters below to find and compare flights from Sioux City to Knoxville that are best for you.

Fly from

Sioux City

Fly to

Knoxville

Route

Depart

Return

Price

Sioux CityKnoxville

SUX - TYS

SUXTYS

Sioux City Sioux Gateway

Tue 9/2

6:48 pm-6:10 pm

2 stops22h 22m

Knoxville McGhee Tyson

Sat 9/6

7:20 am-6:13 pm

2 stops11h 53m

$463

Sioux CityKnoxville

SUX - TYS

SUXTYS

Sioux City Sioux Gateway

Wed 8/27

7:49 am-10:37 pm

1 stop13h 48m

$494

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/18

Best time to book a flight from Sioux City to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Sioux City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Sioux City to Knoxville

What is the cheapest month to book a flight from Sioux City to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Sioux City to Knoxville (average of $294). Flying from Sioux City to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Sioux City to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Sioux City to Knoxville?

    Airlines like United Airlines fly from Sioux City to Knoxville in about 22h 22m. The time it takes to get you to your destination can typically vary by up to . The distance from Sioux City to Knoxville is about 804 mi.

  • Can I find deals for flights from Sioux City to Knoxville that include hotel bookings?

    Yes. In addition to deals on Sioux City to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Sioux City to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Sioux City to Knoxville.

  • Can I find deals for business class flights from Sioux City to Knoxville?

    Yes. Cheapflights offers flight deals from Sioux City to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Sioux City to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Sioux City to Knoxville (average of $294). Flying from Sioux City to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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