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$135+ Cheap flights from Rochester to Knoxville (ROC - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/22. Fares are subject to change and may not be available on all flights or dates of travel.
ROC — TYS
Jul 6 — Jul 131
Sun 7/6
Sun 7/13
1 adult, Economy
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Cheapflights Tip: The best prices from Rochester Greater Rochester Intl to Knoxville McGhee Tyson are usually found in February or September, booked 65 days in advance, depart on a Tuesday or Wednesday and return on a Wednesday

Cheap flight deals from Rochester to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Rochester (ROC) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 1, 2025.

Round-trip from

$245
(Mytrip)

One-way from

$135
(Delta)

Popular in

April

Cheapest in

February

Average price

$368
From Rochester Greater Rochester Intl to Knoxville McGhee Tyson
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One-way flight from Rochester Greater Rochester Intl to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 10% potential increase in price ($40 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Rochester to Knoxville

Cheapest flights from Rochester to Knoxville
Explore the most affordable flight options available from Rochester to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 1, 2025.

This Mytrip deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1411:13 amROC - TYS
2 stops23h 03mMultiple Airlines
Mon 8/186:00 amTYS - ROC
1 stop10h 39mMultiple Airlines
Deal found 6/30$245
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2412:15 pmROC - TYS
1 stop5h 58mDelta
Tue 10/286:30 amTYS - ROC
1 stop5h 58mDelta
Deal found 6/30$249
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2012:08 pmROC - TYS
2 stops6h 57mAmerican Airlines
Tue 9/3012:15 pmTYS - ROC
1 stop5h 00mAmerican Airlines
Deal found 6/30$254
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/35:40 pmROC - TYS
1 stop4h 41mUnited Airlines
Thu 11/65:45 amTYS - ROC
2 stops7h 02mUnited Airlines
Deal found 6/30$274

Cheapflights Fare Finder

Customize your flight search to find flights from Rochester to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 1, 2025.
Use the filters below to find and compare flights from Rochester to Knoxville that are best for you.

Fly from

Rochester

Fly to

Knoxville

Route

Depart

Return

Price

RochesterKnoxville

ROC - TYS

ROCTYS

Rochester Greater Rochester Intl

Thu 8/14

11:13 am-10:16 am

2 stops23h 03m

Knoxville McGhee Tyson

Mon 8/18

6:00 am-4:39 pm

1 stop10h 39m

$245

RochesterKnoxville

ROC - TYS

ROCTYS

Rochester Greater Rochester Intl

Fri 10/24

12:15 pm-6:13 pm

1 stop5h 58m

Knoxville McGhee Tyson

Tue 10/28

6:30 am-12:28 pm

1 stop5h 58m

$249

RochesterKnoxville

ROC - TYS

ROCTYS

Rochester Greater Rochester Intl

Sat 9/20

12:08 pm-7:05 pm

2 stops6h 57m

Knoxville McGhee Tyson

Tue 9/30

12:15 pm-5:15 pm

1 stop5h 00m

$254

RochesterKnoxville

ROC - TYS

ROCTYS

Rochester Greater Rochester Intl

Mon 11/3

5:40 pm-10:21 pm

1 stop4h 41m

Knoxville McGhee Tyson

Thu 11/6

5:45 am-12:47 pm

2 stops7h 02m

$274

RochesterKnoxville

ROC - TYS

ROCTYS

Rochester Greater Rochester Intl

Tue 7/22

6:00 am-10:46 am

1 stop4h 46m

$135

RochesterKnoxville

ROC - TYS

ROCTYS

Rochester Greater Rochester Intl

Tue 7/8

6:00 am-5:05 pm

2 stops11h 05m

$170

RochesterKnoxville

ROC - TYS

ROCTYS

Rochester Greater Rochester Intl

Wed 8/20

6:40 am-1:02 pm

3 stops30h 22m

$226

RochesterKnoxville

ROC - TYS

ROCTYS

Rochester Greater Rochester Intl

Tue 10/7

11:56 am-6:58 pm

2 stops7h 02m

$244

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/30

Best time to book a flight from Rochester to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Rochester with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Rochester to Knoxville

How far ahead should I book a flight from Rochester to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from Rochester to Knoxville. Price data was last updated on June 27, 2025.

Booking 64 days in advance of your planned departure date is, on average, the best time to get cheap flights from Rochester to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Rochester to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Rochester to Knoxville (average of $296). Flying from Rochester to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ROC to TYS?

Find hourly flight availability from Rochester to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 1, 2025.

One of the essential ways to save on airfare from Rochester to Knoxville is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight at noon could potentially save you up to 12% on airfare.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated July 1, 2025.
Read through reviews of airlines operating flights from Rochester to Knoxville, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,974 reviews

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
8.0
Very good
7,974 reviews
Delta
8.0
Very good
7,974 reviews

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
8,858 reviews
Delta
8.0
Very good
7,974 reviews

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,974 reviews

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Rochester to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Rochester to Knoxville round-trip?

    Our cheapest airline available from Rochester to Knoxville is Delta. Our recent data shows that you can find tickets from as low as $249 on this airline. Additional options worth looking into are American Airlines and United Airlines, starting at $254 and $274 round-trip. Delta is currently priced 29% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Rochester to Knoxville one-way?

    For one-way options, check prices for Delta. According to our data, you can fly for as low as $135. Users have also found prices from $170 and $244 on United Airlines and American Airlines, respectively.

  • Can I find deals for flights from Rochester to Knoxville that include hotel bookings?

    Yes. In addition to deals on Rochester to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Rochester to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Rochester to Knoxville.

  • Can I find deals for business class flights from Rochester to Knoxville?

    Yes. Cheapflights offers flight deals from Rochester to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Rochester to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Rochester to Knoxville (average of $296). Flying from Rochester to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Rochester?

Book flights to Rochester if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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Top 3 airlines flying from Rochester to Knoxville

Discover the top 3 airlines that operate flights from Rochester to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$238Average$323FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$248Average$341FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$248Average$373FlexibilityNo cancel feeOn-time71%

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