$129+ Cheap flights from Rochester to Knoxville (ROC - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/27. Fares are subject to change and may not be available on all flights or dates of travel.
ROC — TYS
Jun 13 — Jun 201
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Rochester to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Rochester to Knoxville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Rochester to KnoxvilleExplore the most affordable flight options available from Rochester to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 14, 2026.
Explore the most affordable flight options available from Rochester to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 14, 2026.
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:00 am
ROC
- TYS
1 stop5h 09m
Delta
Wed 6/245:35 pm
TYS
- ROC
1 stop5h 42m
Delta
Deal found 5/13![Delta logo]()
$311
This United Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:00 am
ROC
- TYS
2 stops8h 27m
United Airlines
Wed 8/127:20 pm
TYS
- ROC
1 stop4h 24m
United Airlines
Deal found 5/11![United Airlines logo]()
$316
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/75:00 am
ROC
- TYS
1 stop5h 36m
American Airlines
Sat 6/136:07 pm
TYS
- ROC
1 stop5h 25m
American Airlines
Deal found 5/13![American Airlines logo]()
$325
This United Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:00 am
ROC
- TYS
2 stops8h 27m
United Airlines
Sat 6/135:45 am
TYS
- ROC
1 stop4h 08m
United Airlines
Deal found 5/13![United Airlines logo]()
$330
This Delta deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:05 am
ROC
- TYS
1 stop4h 15m
Delta
Fri 8/215:15 pm
TYS
- ROC
1 stop6h 08m
Delta
Deal found 5/12![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/256:00 am
ROC
- TYS
1 stop5h 04m
Delta
Thu 5/286:00 am
TYS
- ROC
1 stop5h 54m
Delta
Deal found 5/11![Delta logo]()
$340
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:46 pm
ROC
- TYS
1 stop5h 01m
American Airlines
Sat 5/303:40 pm
TYS
- ROC
2 stops8h 12m
American Airlines
Deal found 5/10![American Airlines logo]()
$345
This Delta deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/196:00 am
ROC
- TYS
1 stop5h 09m
Delta
Sun 6/215:25 pm
TYS
- ROC
1 stop5h 29m
Delta
Deal found 5/14![Delta logo]()
$348
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/255:00 am
ROC
- TYS
1 stop5h 36m
American Airlines
Sun 5/316:12 am
TYS
- ROC
1 stop4h 10m
American Airlines
Deal found 5/10![American Airlines logo]()
$354
This Southwest deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/115:50 pm
ROC
- TYS
1 stop4h 40m
Southwest
Wed 6/1712:45 pm
TYS
- ROC
2 stops10h 00m
Southwest
Deal found 5/13![Southwest logo]()
$359
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/197:38 pm
ROC
- TYS
2 stops21h 48m
Multiple Airlines
Sun 8/2310:54 am
TYS
- ROC
1 stop8h 09m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$361
This Southwest deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/511:55 am
ROC
- TYS
2 stops7h 00m
Southwest
Wed 8/127:00 am
TYS
- ROC
2 stops10h 30m
Southwest
Deal found 5/11![Southwest logo]()
$366
Best flights from Rochester to KnoxvilleDiscover carefully curated flight deals from Rochester to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 14, 2026.
Discover carefully curated flight deals from Rochester to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 14, 2026.
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/136:20 am
ROC
- TYS
1 stop4h 32m
Delta
Tue 6/1611:07 am
TYS
- ROC
1 stop6h 01m
Delta
Deal found 5/13![Delta logo]()
$311
This United Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:00 am
ROC
- TYS
2 stops10h 58m
United Airlines
Sat 8/296:02 pm
TYS
- ROC
1 stop4h 47m
United Airlines
Deal found 5/11![United Airlines logo]()
$316
This Southwest deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/135:25 pm
ROC
- TYS
1 stop3h 55m
Southwest
Tue 6/1612:45 pm
TYS
- ROC
2 stops10h 00m
Southwest
Deal found 5/13![Southwest logo]()
$345
This Delta deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:00 am
ROC
- TYS
1 stop5h 09m
Delta
Wed 6/245:35 pm
TYS
- ROC
1 stop5h 42m
Delta
Deal found 5/14![Delta logo]()
$311
This United Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:00 am
ROC
- TYS
2 stops8h 27m
United Airlines
Wed 8/127:20 pm
TYS
- ROC
1 stop4h 24m
United Airlines
Deal found 5/11![United Airlines logo]()
$316
This Delta deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:05 am
ROC
- TYS
1 stop4h 15m
Delta
Fri 8/215:15 pm
TYS
- ROC
1 stop6h 08m
Delta
Deal found 5/14![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/256:00 am
ROC
- TYS
1 stop5h 04m
Delta
Thu 5/286:00 am
TYS
- ROC
1 stop5h 54m
Delta
Deal found 5/11![Delta logo]()
$340
This Delta deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/196:00 am
ROC
- TYS
1 stop5h 09m
Delta
Sun 6/215:25 pm
TYS
- ROC
1 stop5h 29m
Delta
Deal found 5/14![Delta logo]()
$348
Last-minute flights from Rochester to KnoxvilleDiscover last-minute flight deals from Rochester to Knoxville. Data last updated May 14, 2026 and is based on user searches.
Discover last-minute flight deals from Rochester to Knoxville. Data last updated May 14, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/256:00 am
ROC
- TYS
1 stop5h 04m
Delta
Thu 5/286:00 am
TYS
- ROC
1 stop5h 54m
Delta
Deal found 5/11![Delta logo]()
$340
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/255:00 am
ROC
- TYS
1 stop5h 36m
American Airlines
Sun 5/316:12 am
TYS
- ROC
1 stop4h 10m
American Airlines
Deal found 5/10![American Airlines logo]()
$354
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:17 pm
ROC
- TYS
1 stop5h 39m
Delta
Sat 5/305:40 am
TYS
- ROC
1 stop6h 28m
Delta
Deal found 5/11![Delta logo]()
$369
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2611:51 am
ROC
- TYS
1 stop6h 38m
American Airlines
Sat 5/305:00 am
TYS
- ROC
2 stops6h 21m
American Airlines
Deal found 5/11![American Airlines logo]()
$374
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:46 pm
ROC
- TYS
1 stop5h 01m
American Airlines
Sat 5/303:40 pm
TYS
- ROC
2 stops8h 12m
American Airlines
Deal found 5/10![American Airlines logo]()
$345
This United Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:00 am
ROC
- TYS
2 stops8h 27m
United Airlines
Sat 6/135:45 am
TYS
- ROC
1 stop4h 08m
United Airlines
Deal found 5/13![United Airlines logo]()
$330
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/75:00 am
ROC
- TYS
1 stop5h 36m
American Airlines
Sat 6/136:07 pm
TYS
- ROC
1 stop5h 25m
American Airlines
Deal found 5/13![American Airlines logo]()
$325
This Southwest deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/115:50 pm
ROC
- TYS
1 stop4h 40m
Southwest
Wed 6/1712:45 pm
TYS
- ROC
2 stops10h 00m
Southwest
Deal found 5/13![Southwest logo]()
$359
This Southwest deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/136:00 am
ROC
- TYS
2 stops8h 05m
Southwest
Tue 6/1612:45 pm
TYS
- ROC
2 stops10h 00m
Southwest
Deal found 5/13![Southwest logo]()
$384
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:00 am
ROC
- TYS
1 stop5h 09m
Delta
Wed 6/245:35 pm
TYS
- ROC
1 stop5h 42m
Delta
Deal found 5/13![Delta logo]()
$311
This Delta deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/196:00 am
ROC
- TYS
1 stop5h 09m
Delta
Sun 6/215:25 pm
TYS
- ROC
1 stop5h 29m
Delta
Deal found 5/14![Delta logo]()
$348
This United Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/255:52 pm
ROC
- TYS
1 stop4h 42m
United Airlines
Sat 7/45:45 am
TYS
- ROC
1 stop4h 07m
United Airlines
Deal found 5/14![United Airlines logo]()
$402
One-way flights from Rochester to KnoxvilleSearch for one-way flight options from Rochester to Knoxville. Find affordable one-way fares based on user searches. Data last updated May 14, 2026.
Search for one-way flight options from Rochester to Knoxville. Find affordable one-way fares based on user searches. Data last updated May 14, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:38 pm
ROC
- TYS
2 stops27h 28m
Multiple Airlines
Deal found 5/11![Multiple Airlines logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/307:38 pm
ROC
- TYS
2 stops27h 28m
Multiple Airlines
Deal found 5/13![Multiple Airlines logo]()
$147
This United Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:52 pm
ROC
- TYS
1 stop6h 17m
United Airlines
Deal found 5/13![United Airlines logo]()
$156
This American Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/95:20 am
ROC
- TYS
1 stop5h 28m
American Airlines
Deal found 5/14![American Airlines logo]()
$158
This Southwest deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:00 am
ROC
- TYS
2 stops11h 00m
Southwest
Deal found 5/14![Southwest logo]()
$163
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/195:46 pm
ROC
- TYS
1 stop5h 44m
American Airlines
Deal found 5/13![American Airlines logo]()
$168
This Delta deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2112:26 pm
ROC
- TYS
1 stop4h 53m
Delta
Deal found 5/12![Delta logo]()
$170
This Southwest deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/288:25 am
ROC
- TYS
2 stops8h 45m
Southwest
Deal found 5/14![Southwest logo]()
$173
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/306:22 pm
ROC
- TYS
1 stop5h 39m
Delta
Deal found 5/13![Delta logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/312:04 pm
ROC
- TYS
2 stops11h 29m
Multiple Airlines
Deal found 5/13![Multiple Airlines logo]()
$188
Find flight deals from Rochester to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Rochester (ROC) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 14, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $311 (Delta) |
One-way from | $129 (Kiwi.com) |
Popular in | March |
Cheapest in | September |
Average price | $416 |
Cheapflights Fare Finder
Customize your flight search to find flights from Rochester to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 14, 2026.
Use the filters below to find and compare flights from Rochester to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
RochesterKnoxville
ROC - TYS
ROCTYS
Greater Rochester Intl
Sat 6/13
6:20 am-10:52 am
1 stop4h 32m
Knoxville McGhee Tyson
Tue 6/16
11:07 am-5:08 pm
1 stop6h 01m
$311
RochesterKnoxville
ROC - TYS
ROCTYS
Greater Rochester Intl
Tue 6/16
6:00 am-11:09 am
1 stop5h 09m
Knoxville McGhee Tyson
Wed 6/24
5:35 pm-11:17 pm
1 stop5h 42m
$311
RochesterKnoxville
ROC - TYS
ROCTYS
Greater Rochester Intl
Sat 8/22
6:00 am-4:58 pm
2 stops10h 58m
Knoxville McGhee Tyson
Sat 8/29
6:02 pm-10:49 pm
1 stop4h 47m
$316
RochesterKnoxville
ROC - TYS
ROCTYS
Greater Rochester Intl
Wed 8/5
6:00 am-2:27 pm
2 stops8h 27m
Knoxville McGhee Tyson
Wed 8/12
7:20 pm-11:44 pm
1 stop4h 24m
$316
Quickest round-trip
RochesterKnoxville
ROC - TYS
ROCTYS
Greater Rochester Intl
Sun 8/16
6:05 am-10:20 am
1 stop4h 15m
Knoxville McGhee Tyson
Fri 8/21
5:15 pm-11:23 pm
1 stop6h 08m
$339
RochesterKnoxville
ROC - TYS
ROCTYS
Greater Rochester Intl
Mon 5/25
6:00 am-11:04 am
1 stop5h 04m
Knoxville McGhee Tyson
Thu 5/28
6:00 am-11:54 am
1 stop5h 54m
$340
RochesterKnoxville
ROC - TYS
ROCTYS
Greater Rochester Intl
Sat 6/13
5:25 pm-9:20 pm
1 stop3h 55m
Knoxville McGhee Tyson
Tue 6/16
12:45 pm-10:45 pm
2 stops10h 00m
$345
RochesterKnoxville
ROC - TYS
ROCTYS
Greater Rochester Intl
Fri 6/19
6:00 am-11:09 am
1 stop5h 09m
Knoxville McGhee Tyson
Sun 6/21
5:25 pm-10:54 pm
1 stop5h 29m
$348
Cheapest one-way
RochesterKnoxville
ROC - TYS
ROCTYS
Greater Rochester Intl
Thu 5/28
6:46 pm-11:47 pm
1 stop5h 01m
$156
RochesterKnoxville
ROC - TYS
ROCTYS
Greater Rochester Intl
Wed 5/27
5:00 am-10:36 am
1 stop5h 36m
$156
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from Rochester to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Rochester to Knoxville in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Rochester-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Rochester-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Rochester-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Rochester-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Rochester-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Rochester to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Rochester with our price prediction graph.
ROC-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Rochester to Knoxville
How far ahead should I book a flight from Rochester to Knoxville?
Booking 45 days in advance of your planned departure date is, on average, the best time to get cheap flights from Rochester to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Rochester to Knoxville?
Currently, September is the cheapest month in which you can book a flight from Rochester to Knoxville (average of $293). Flying from Rochester to Knoxville in March is currently the most expensive (average of $453). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Rochester to Knoxville?
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated May 14, 2026.
Read through reviews of airlines operating flights from Rochester to Knoxville, such as Delta,United Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Entertainment
7.8
Food
7.2
Comfort
7.8
Overall
7.9
Boarding
8.1
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Crew
8.5
Entertainment
7.8
Food
7.2
Comfort
7.8
Overall
7.9
Boarding
8.1
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Crew
8.5
Entertainment
7.8
Food
7.2
Comfort
7.8
Overall
7.9
Boarding
8.1
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Crew
8.5
Entertainment
7.8
Food
7.2
Comfort
7.8
Overall
7.9
Boarding
8.1
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Related info for your journey
Find useful and relevant information for your journey from Rochester to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa
Oak Ridge
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Knoxville flight routes
Other flight options
Other flights from Rochester
Popular flights
Alternative routes for Rochester to Knoxville
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Knoxville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Rochester to Knoxville by cabin class
Find flights from Rochester to Knoxville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 14, 2026.
Rochester and Knoxville flights
Browse other Rochester and Knoxville flight options. Last updated on May 14, 2026.
Other flights from Rochester
Browse through other flights departing from Rochester. Flights are based on user searches made on Cheapflights and were last updated on May 14, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Rochester to Knoxville
Discover the top 3 airlines that operate flights from Rochester to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$155 | Average$335 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$179 | Average$343 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$248 | Average$375 | FlexibilityNo cancel fee | On-time71% |