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$140+ Cheap flights from Syracuse to Knoxville (SYR - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/15. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — TYS
Jul 27 — Aug 31
Mon 7/27
Mon 8/3
1 adult, Economy
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Cheap flight deals from Syracuse to Knoxville

Cheapest flights from Syracuse to Knoxville
Explore the most affordable flight options available from Syracuse to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 27, 2026.

This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/294:57 pm
SYR
-
TYS
1 stop21h 51m
Allegiant Air
Wed 8/512:56 pm
TYS
-
SYR
1 stop29h 40m
Allegiant Air
Deal found 6/24$236
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/294:57 pm
SYR
-
TYS
1 stop21h 51m
Allegiant Air
Thu 8/67:45 am
TYS
-
SYR
1 stop10h 51m
Allegiant Air
Deal found 6/24$242
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/297:34 pm
SYR
-
TYS
1 stop4h 17m
American Airlines
Sat 8/16:10 pm
TYS
-
SYR
1 stop4h 36m
American Airlines
Deal found 6/25$277
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/294:57 pm
SYR
-
TYS
1 stop21h 51m
Multiple Airlines
Thu 8/68:29 pm
TYS
-
SYR
2 stops22h 53m
Multiple Airlines
Deal found 6/24$285
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:50 pm
SYR
-
TYS
1 stop4h 56m
Delta
Fri 11/205:15 pm
TYS
-
SYR
1 stop5h 43m
Delta
Deal found 6/23$293
This Kiwi.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/67:26 pm
SYR
-
TYS
1 stop13h 10m
Allegiant Air
Sun 8/97:45 am
TYS
-
SYR
1 stop10h 51m
Allegiant Air
Deal found 6/25$302
This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:00 am
SYR
-
TYS
1 stop4h 58m
Delta
Sat 8/154:15 pm
TYS
-
SYR
1 stop5h 15m
Delta
Deal found 6/22$308
This Delta deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:00 am
SYR
-
TYS
1 stop4h 58m
Delta
Sun 8/305:40 am
TYS
-
SYR
1 stop5h 53m
Delta
Deal found 6/26$309
This United Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:00 am
SYR
-
TYS
2 stops10h 58m
United Airlines
Mon 8/317:20 pm
TYS
-
SYR
1 stop4h 26m
United Airlines
Deal found 6/25$314
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:26 pm
SYR
-
TYS
1 stop13h 10m
Multiple Airlines
Sun 8/166:09 pm
TYS
-
SYR
1 stop25h 13m
Multiple Airlines
Deal found 6/23$328
This Kiwi.com deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/155:45 pm
SYR
-
TYS
2 stops43h 06m
Allegiant Air
Sat 8/221:54 pm
TYS
-
SYR
1 stop21h 04m
Allegiant Air
Deal found 6/26$336

Find flight deals from Syracuse to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Syracuse (SYR) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$236
(Kiwi.com)

One-way from

$140
(Kiwi.com)

Popular in

May

Cheapest in

January

Average price

$348
Provider with most accurate pricing for Syracuse Hancock Intl-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Syracuse Hancock Intl-Knoxville McGhee Tyson flights.
Search Deals
From Syracuse Hancock Intl to Knoxville McGhee Tyson
Search Deals
One-way flight from Syracuse Hancock Intl to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($64 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($24 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Syracuse to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 27, 2026.
Use the filters below to find and compare flights from Syracuse to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

SyracuseKnoxville

SYR - TYS

SYRTYS

Syracuse Hancock Intl

Sat 8/15

6:00 am-10:58 am

1 stop4h 58m

Knoxville McGhee Tyson

Sat 8/22

4:15 pm-9:30 pm

1 stop5h 15m

$277

SyracuseKnoxville

SYR - TYS

SYRTYS

Syracuse Hancock Intl

Wed 8/5

6:00 am-10:58 am

1 stop4h 58m

Knoxville McGhee Tyson

Mon 8/17

5:15 pm-11:17 pm

1 stop6h 02m

$293

SyracuseKnoxville

SYR - TYS

SYRTYS

Syracuse Hancock Intl

Thu 8/27

6:00 am-10:58 am

1 stop4h 58m

Knoxville McGhee Tyson

Sun 8/30

5:40 am-11:33 am

1 stop5h 53m

$309

SyracuseKnoxville

SYR - TYS

SYRTYS

Syracuse Hancock Intl

Fri 8/28

6:00 am-4:58 pm

2 stops10h 58m

Knoxville McGhee Tyson

Mon 8/31

7:20 pm-11:46 pm

1 stop4h 26m

$314

SyracuseKnoxville

SYR - TYS

SYRTYS

Syracuse Hancock Intl

Fri 8/7

7:17 pm-11:52 pm

1 stop4h 35m

Knoxville McGhee Tyson

Tue 8/11

5:15 pm-11:17 pm

1 stop6h 02m

$324

SyracuseKnoxville

SYR - TYS

SYRTYS

Syracuse Hancock Intl

Thu 7/23

6:00 am-1:16 pm

1 stop7h 16m

Knoxville McGhee Tyson

Sun 7/26

6:05 am-11:36 am

1 stop5h 31m

$324

SyracuseKnoxville

SYR - TYS

SYRTYS

Syracuse Hancock Intl

Tue 9/1

7:58 am-3:57 pm

2 stops7h 59m

Knoxville McGhee Tyson

Tue 9/8

6:05 pm-11:55 pm

2 stops5h 50m

$401

SyracuseKnoxville

SYR - TYS

SYRTYS

Syracuse Hancock Intl

Fri 8/7

5:17 pm-10:58 pm

1 stop5h 41m

Knoxville McGhee Tyson

Tue 8/11

6:05 pm-11:55 pm

2 stops5h 50m

$431

SyracuseKnoxville

SYR - TYS

SYRTYS

Syracuse Hancock Intl

Thu 8/27

6:00 am-4:58 pm

2 stops10h 58m

Knoxville McGhee Tyson

Sun 8/30

7:00 am-2:14 pm

2 stops7h 14m

$444

SyracuseKnoxville

SYR - TYS

SYRTYS

Syracuse Hancock Intl

Sat 8/22

7:55 pm-11:59 pm

1 stop4h 04m

Knoxville McGhee Tyson

Wed 8/26

7:00 am-2:14 pm

2 stops7h 14m

$500

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/23

Showing 1-10 of 17 resultsSorted by cheapest first
1
2

Compare providers for flights from Syracuse to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Syracuse to Knoxville in June.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Syracuse-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Syracuse-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Syracuse-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Syracuse-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Syracuse-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Syracuse to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Knoxville

How far ahead should I book a flight from Syracuse to Knoxville?

Booking 36 days in advance of your planned departure date is, on average, the best time to get cheap flights from Syracuse to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Syracuse to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Syracuse to Knoxville (average of $260). Flying from Syracuse to Knoxville in May is currently the most expensive (average of $657). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Syracuse to Knoxville?

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated June 27, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from Syracuse to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.8
Good
8,451 reviews

Crew

8.5

Food

7.2

Comfort

7.8

Boarding

8.1

Entertainment

7.8

Overall

7.8

Reviews

1 / 20
2.0
Mediocre

Barney,May 2026

JFK - ATL

Terrible flight. Late, reduced beverage service, lack of headphones, entertainment service didn't work
Delta
7.8
Good
8,451 reviews
Delta
7.8
Good
8,451 reviews

Crew

8.5

Food

7.2

Comfort

7.8

Boarding

8.1

Entertainment

7.8

Overall

7.8

Reviews

1 / 20
2.0
Mediocre

Barney,May 2026

JFK - ATL

Terrible flight. Late, reduced beverage service, lack of headphones, entertainment service didn't work
United Airlines
7.4
Good
9,896 reviews
Delta
7.8
Good
8,451 reviews

Crew

8.5

Food

7.2

Comfort

7.8

Boarding

8.1

Entertainment

7.8

Overall

7.8

Reviews

1 / 20
2.0
Mediocre

Barney,May 2026

JFK - ATL

Terrible flight. Late, reduced beverage service, lack of headphones, entertainment service didn't work
American Airlines
7.1
Good
11,779 reviews
Delta
7.8
Good
8,451 reviews

Crew

8.5

Food

7.2

Comfort

7.8

Boarding

8.1

Entertainment

7.8

Overall

7.8

Reviews

1 / 20
2.0
Mediocre

Barney,May 2026

JFK - ATL

Terrible flight. Late, reduced beverage service, lack of headphones, entertainment service didn't work

Related info for your journey

Find useful and relevant information for your journey from Syracuse to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Syracuse to Knoxville?

    For as low as $277, Delta can have you in Knoxville from Syracuse in 4h 58m. Syracuse and Knoxville are separated by a distance of 656 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Syracuse to Knoxville round-trip?

    Our cheapest airline available from Syracuse to Knoxville is American Airlines. Our recent data shows that you can find tickets from as low as $248 on this airline. Additional options worth looking into are Delta and United Airlines, starting at $248 and $262 round-trip. American Airlines is currently priced 37% below the average price you’ll pay for this route.

  • Can I find deals for flights from Syracuse to Knoxville that include hotel bookings?

    Yes. In addition to deals on Syracuse to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Knoxville.

  • Can I find deals for business class flights from Syracuse to Knoxville?

    Yes. Cheapflights offers flight deals from Syracuse to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Syracuse to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Syracuse to Knoxville (average of $260). Flying from Syracuse to Knoxville in May is currently the most expensive (average of $657). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Syracuse to Knoxville

Discover the top 3 airlines that operate flights from Syracuse to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$371FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$350FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$262Average$412FlexibilityNo cancel feeOn-time69%

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