$238+ Cheap flights from Syracuse to Knoxville (SYR - TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/13. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — TYS
Dec 9 — Dec 161
Round-trip
1 adult, Economy
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Find cheap flights from Syracuse to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Syracuse to Knoxville
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Cheapest flights from Syracuse to KnoxvilleExplore the most affordable flight options available from Syracuse to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 9, 2026.
Explore the most affordable flight options available from Syracuse to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 9, 2026.
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/206:00 am -
1 stop4h 26m
Mon 12/286:38 pm -
1 stop4h 16m
Deal found 11/6![American Airlines logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/317:21 pm -
1 stop15h 25m
Wed 1/64:09 pm -
1 stop18h 45m
Deal found 11/5![Allegiant Air logo]()
$351
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/307:11 pm -
1 stop25h 07m
Wed 1/64:09 pm -
1 stop18h 45m
Deal found 11/5![Allegiant Air logo]()
$376
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:35 pm -
1 stop4h 24m
Fri 11/275:45 am -
1 stop3h 57m
Deal found 11/8![United Airlines logo]()
$379
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:00 am -
1 stop4h 39m
Fri 11/206:50 am -
1 stop3h 59m
Deal found 11/4![American Airlines logo]()
$391
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/216:56 pm -
2 stops20h 38m
Tue 12/297:00 am -
1 stop10h 52m
Deal found 11/6![Multiple Airlines logo]()
$393
This Delta deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/226:00 am -
1 stop5h 28m
Fri 11/275:40 am -
1 stop5h 41m
Deal found 11/7![Delta logo]()
$399
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/206:00 am -
1 stop4h 26m
Tue 12/297:15 am -
2 stops8h 27m
Deal found 11/6![American Airlines logo]()
$405
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/317:29 pm -
2 stops15h 17m
Wed 1/64:09 pm -
1 stop18h 45m
Deal found 11/5![Multiple Airlines logo]()
$407
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2212:27 pm -
1 stop6h 22m
Mon 11/305:25 pm -
1 stop5h 35m
Deal found 11/5![Delta logo]()
$414
Best flights from Syracuse to KnoxvilleDiscover carefully curated flight deals from Syracuse to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 9, 2026.
Discover carefully curated flight deals from Syracuse to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 9, 2026.
This Delta deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/2912:20 pm -
1 stop4h 46m
Sun 1/317:08 am -
1 stop4h 32m
Deal found 11/7![Delta logo]()
$349
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2310:17 am -
2 stops10h 37m
Fri 11/275:45 am -
1 stop3h 57m
Deal found 11/8![United Airlines logo]()
$384
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/412:10 pm -
1 stop4h 35m
Mon 12/77:26 pm -
1 stop4h 26m
Deal found 11/6![Delta logo]()
$349
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/297:25 pm -
1 stop4h 34m
Sun 1/316:30 am -
2 stops7h 49m
Deal found 11/6![United Airlines logo]()
$454
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:00 am -
1 stop7h 13m
Fri 11/2010:33 am -
2 stops13h 10m
Deal found 11/8![United Airlines logo]()
$531
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/115:16 pm -
1 stop4h 17m
Wed 1/137:00 am -
1 stop6h 29m
Deal found 11/5![Delta logo]()
$577
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:17 am -
2 stops10h 37m
Thu 11/194:30 pm -
2 stops7h 13m
Deal found 11/7![United Airlines logo]()
$560
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/57:25 pm -
2 stops25h 40m
Tue 2/96:30 am -
2 stops7h 49m
Deal found 11/6![United Airlines logo]()
$657
Last-minute flights from Syracuse to KnoxvilleDiscover last-minute flight deals from Syracuse to Knoxville. Data last updated November 9, 2026 and is based on user searches.
Discover last-minute flight deals from Syracuse to Knoxville. Data last updated November 9, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:00 am -
1 stop4h 39m
Fri 11/206:50 am -
1 stop3h 59m
Deal found 11/4![American Airlines logo]()
$391
This Delta deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/226:00 am -
1 stop5h 28m
Fri 11/275:40 am -
1 stop5h 41m
Deal found 11/7![Delta logo]()
$399
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2212:27 pm -
1 stop6h 22m
Mon 11/305:25 pm -
1 stop5h 35m
Deal found 11/5![Delta logo]()
$414
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:35 pm -
1 stop4h 24m
Fri 11/275:45 am -
1 stop3h 57m
Deal found 11/8![United Airlines logo]()
$379
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/206:00 am -
1 stop4h 26m
Mon 12/286:38 pm -
1 stop4h 16m
Deal found 11/6![American Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/206:00 am -
1 stop4h 26m
Tue 12/297:15 am -
2 stops8h 27m
Deal found 11/6![American Airlines logo]()
$405
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/216:56 pm -
2 stops20h 38m
Tue 12/297:00 am -
1 stop10h 52m
Deal found 11/6![Multiple Airlines logo]()
$393
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/307:11 pm -
1 stop25h 07m
Wed 1/64:09 pm -
1 stop18h 45m
Deal found 11/5![Allegiant Air logo]()
$376
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/317:21 pm -
1 stop15h 25m
Wed 1/64:09 pm -
1 stop18h 45m
Deal found 11/5![Allegiant Air logo]()
$351
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/317:29 pm -
2 stops15h 17m
Wed 1/64:09 pm -
1 stop18h 45m
Deal found 11/5![Multiple Airlines logo]()
$407
One-way flights from Syracuse to KnoxvilleSearch for one-way flight options from Syracuse to Knoxville. Find affordable one-way fares based on user searches. Data last updated November 9, 2026.
Search for one-way flight options from Syracuse to Knoxville. Find affordable one-way fares based on user searches. Data last updated November 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/138:45 pm -
1 stop24h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Allegiant Air logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/139:21 pm -
2 stops20h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Multiple Airlines logo]()
$265
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:45 pm -
1 stop14h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Allegiant Air logo]()
$292
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:08 am -
2 stops21h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Multiple Airlines logo]()
$381
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1211:46 am -
1 stop5h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![American Airlines logo]()
$434
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:40 am -
2 stops11h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![United Airlines logo]()
$439
Find flight deals from Syracuse to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Syracuse (SYR) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $327 (Kiwi.com) |
One-way from | $238 (Kiwi.com) |
Popular in | August |
Cheapest in | January |
Average price | $382 |
Cheapflights Fare Finder
Customize your flight search to find flights from Syracuse to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 9, 2026.
Use the filters below to find and compare flights from Syracuse to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
SyracuseKnoxville
SYR Syracuse Hancock Intl - TYS Knoxville McGhee Tyson
SYRTYS
Syracuse Hancock Intl
Fri 11/13
8:45 pm-9:00 pm
1 stop24h 15m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$271
SyracuseKnoxville
SYR Syracuse Hancock Intl - TYS Knoxville McGhee Tyson
SYRTYS
Syracuse Hancock Intl
Thu 11/12
5:45 pm-7:45 am
1 stop14h 00m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$292
SyracuseKnoxville
SYR Syracuse Hancock Intl - TYS Knoxville McGhee Tyson
SYRTYS
Syracuse Hancock Intl
Fri 1/29
12:20 pm-5:06 pm
1 stop4h 46m
Knoxville McGhee Tyson
Sun 1/31
7:08 am-11:40 am
1 stop4h 32m
$349
SyracuseKnoxville
SYR Syracuse Hancock Intl - TYS Knoxville McGhee Tyson
SYRTYS
Syracuse Hancock Intl
Fri 12/4
12:10 pm-4:45 pm
1 stop4h 35m
Knoxville McGhee Tyson
Mon 12/7
7:26 pm-11:52 pm
1 stop4h 26m
$349
SyracuseKnoxville
SYR Syracuse Hancock Intl - TYS Knoxville McGhee Tyson
SYRTYS
Syracuse Hancock Intl
Fri 11/13
9:21 pm-8:05 am
2 stops34h 44m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$357
SyracuseKnoxville
SYR Syracuse Hancock Intl - TYS Knoxville McGhee Tyson
SYRTYS
Syracuse Hancock Intl
Thu 11/12
10:08 am-7:45 am
2 stops21h 37m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$381
SyracuseKnoxville
SYR Syracuse Hancock Intl - TYS Knoxville McGhee Tyson
SYRTYS
Syracuse Hancock Intl
Mon 11/23
10:17 am-8:54 pm
2 stops10h 37m
Knoxville McGhee Tyson
Fri 11/27
5:45 am-9:42 am
1 stop3h 57m
$384
Quickest round-trip
SyracuseKnoxville
SYR Syracuse Hancock Intl - TYS Knoxville McGhee Tyson
SYRTYS
Syracuse Hancock Intl
Thu 11/12
11:46 am-5:40 pm
1 stop5h 54m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$434
SyracuseKnoxville
SYR Syracuse Hancock Intl - TYS Knoxville McGhee Tyson
SYRTYS
Syracuse Hancock Intl
Thu 11/12
5:40 am-4:59 pm
2 stops11h 19m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$439
SyracuseKnoxville
SYR Syracuse Hancock Intl - TYS Knoxville McGhee Tyson
SYRTYS
Syracuse Hancock Intl
Fri 1/29
7:25 pm-11:59 pm
1 stop4h 34m
Knoxville McGhee Tyson
Sun 1/31
6:30 am-2:19 pm
2 stops7h 49m
$454
Showing 1-10 of 14 resultsSorted by cheapest first
Compare providers for flights from Syracuse to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Syracuse to Knoxville in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Syracuse-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Syracuse-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Syracuse-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Syracuse-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Syracuse-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Syracuse to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Syracuse with our price prediction graph.
SYR-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Syracuse to Knoxville
How far ahead should I book a flight from Syracuse to Knoxville?
Booking 67 days in advance of your planned departure date is, on average, the best time to get cheap flights from Syracuse to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Syracuse to Knoxville?
Currently, January is the cheapest month in which you can book a flight from Syracuse to Knoxville (average of $309). Flying from Syracuse to Knoxville in August is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Syracuse to Knoxville?
Airfare is below average for this route at the moment.
Syracuse to Knoxville flights typically cost between $328 and $479 in January.The cheapest round-trip price found within the last 5 days was $327 on Multiple Airlines (Jan 22-Jan 25).
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated November 9, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from Syracuse to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Food
7.2
Overall
7.8
Comfort
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Entertainment
7.8
Food
7.2
Overall
7.8
Comfort
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Entertainment
7.8
Food
7.2
Overall
7.8
Comfort
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Entertainment
7.8
Food
7.2
Overall
7.8
Comfort
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Related info for your journey
Find useful and relevant information for your journey from Syracuse to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Newport
Bryson City
Crossville
Morristown
Murphy
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Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on November 9, 2026.
Syracuse and Knoxville flights
Browse other Syracuse and Knoxville flight options. Last updated on November 9, 2026.
Other flights from Syracuse
Browse through other flights departing from Syracuse. Flights are based on user searches made on Cheapflights and were last updated on November 9, 2026.
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Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Syracuse to Knoxville
Discover the top 3 airlines that operate flights from Syracuse to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$260 | Average$407 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$270 | Average$365 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$317 | Average$412 | FlexibilityNo cancel fee | On-time69% |