HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Knoxville

$136+ Cheap flights from Syracuse to Knoxville (SYR - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/10. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — TYS
Sep 9 — Sep 161
Wed 9/9
Wed 9/16
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Syracuse to Knoxville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Syracuse to Knoxville

Cheapest flights from Syracuse to Knoxville
Explore the most affordable flight options available from Syracuse to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 10, 2026.

This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/47:52 pm -
1 stop13h 51m
Sat 10/109:36 pm -
1 stop12h 32m
Deal found 8/8$271
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1010:54 am -
1 stop23h 10m
Sat 9/123:56 pm -
1 stop18h 08m
Deal found 8/8$272
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1010:54 am -
1 stop23h 10m
Mon 9/149:00 am -
1 stop7h 55m
Deal found 8/8$286
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:00 am -
1 stop5h 04m
Tue 9/1511:00 am -
1 stop6h 00m
Deal found 8/7$287
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:00 am -
1 stop4h 37m
Sat 9/121:53 pm -
2 stops9h 53m
Deal found 8/6$292
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/141:25 pm -
1 stop6h 30m
Fri 11/206:09 pm -
1 stop5h 50m
Deal found 8/7$303
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1710:54 am -
1 stop23h 10m
Tue 9/223:21 pm -
2 stops42h 43m
Deal found 8/6$304
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:00 am -
2 stops10h 58m
Tue 9/157:20 pm -
1 stop4h 26m
Deal found 8/9$309

Find flight deals from Syracuse to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Syracuse (SYR) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 10, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$271
(Kiwi.com)

One-way from

$136
(Kiwi.com)

Popular in

May

Cheapest in

January

Average price

$462
Provider with most accurate pricing for Syracuse Hancock Intl-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Syracuse Hancock Intl-Knoxville McGhee Tyson flights.
Search Deals
From Syracuse Hancock Intl to Knoxville McGhee Tyson
Search Deals
One-way flight from Syracuse Hancock Intl to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($72 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($24 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in August 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Syracuse to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 10, 2026.
Use the filters below to find and compare flights from Syracuse to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

SyracuseKnoxville

SYR Syracuse Hancock Intl - TYS Knoxville McGhee Tyson

SYRTYS

Syracuse Hancock Intl

Sat 9/19

7:55 pm-11:59 pm

1 stop4h 04m

Knoxville McGhee Tyson

Sat 9/26

7:25 pm-11:46 pm

1 stop4h 21m

$287

SyracuseKnoxville

SYR Syracuse Hancock Intl - TYS Knoxville McGhee Tyson

SYRTYS

Syracuse Hancock Intl

Sat 9/19

6:10 am-10:44 am

1 stop4h 34m

Knoxville McGhee Tyson

Sat 9/26

5:40 am-11:20 am

1 stop5h 40m

$287

SyracuseKnoxville

SYR Syracuse Hancock Intl - TYS Knoxville McGhee Tyson

SYRTYS

Syracuse Hancock Intl

Sat 9/5

6:00 am-10:37 am

1 stop4h 37m

Knoxville McGhee Tyson

Sat 9/12

7:20 pm-11:46 pm

1 stop4h 26m

$287

SyracuseKnoxville

SYR Syracuse Hancock Intl - TYS Knoxville McGhee Tyson

SYRTYS

Syracuse Hancock Intl

Sat 11/14

1:25 pm-7:55 pm

1 stop6h 30m

Knoxville McGhee Tyson

Fri 11/20

6:09 pm-11:59 pm

1 stop5h 50m

$303

SyracuseKnoxville

SYR Syracuse Hancock Intl - TYS Knoxville McGhee Tyson

SYRTYS

Syracuse Hancock Intl

Thu 11/19

6:59 pm-11:57 pm

1 stop4h 58m

Knoxville McGhee Tyson

Mon 11/23

12:34 pm-5:54 pm

1 stop5h 20m

$319

SyracuseKnoxville

SYR Syracuse Hancock Intl - TYS Knoxville McGhee Tyson

SYRTYS

Syracuse Hancock Intl

Thu 11/19

6:59 pm-11:57 pm

1 stop4h 58m

Knoxville McGhee Tyson

Sun 11/22

7:21 pm-11:59 pm

1 stop4h 38m

$319

SyracuseKnoxville

SYR Syracuse Hancock Intl - TYS Knoxville McGhee Tyson

SYRTYS

Syracuse Hancock Intl

Fri 11/6

9:21 pm-3:07 pm

2 stops17h 46m

Knoxville McGhee Tyson

Wed 11/11

10:55 am-9:18 am

1 stop22h 23m

$333
Cheapest one-way

SyracuseKnoxville

SYR Syracuse Hancock Intl - TYS Knoxville McGhee Tyson

SYRTYS

Syracuse Hancock Intl

Mon 8/24

6:08 pm-2:35 pm

1 stop20h 27m

$164

SyracuseKnoxville

SYR Syracuse Hancock Intl - TYS Knoxville McGhee Tyson

SYRTYS

Syracuse Hancock Intl

Thu 9/10

10:54 am-8:41 am

3 stops21h 47m

$209

SyracuseKnoxville

SYR Syracuse Hancock Intl - TYS Knoxville McGhee Tyson

SYRTYS

Syracuse Hancock Intl

Mon 8/24

9:02 pm-10:04 am

2 stops37h 02m

$211

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/8

Showing 1-10 of 16 resultsSorted by cheapest first
1
2

Compare providers for flights from Syracuse to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Syracuse to Knoxville in August.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Syracuse-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Syracuse-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Syracuse-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Syracuse-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Syracuse-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Syracuse to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Knoxville

How far ahead should I book a flight from Syracuse to Knoxville?

Booking 36 days in advance of your planned departure date is, on average, the best time to get cheap flights from Syracuse to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Syracuse to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Syracuse to Knoxville (average of $260). Flying from Syracuse to Knoxville in May is currently the most expensive (average of $657). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Syracuse to Knoxville?

Airfare is below average for this route at the moment.

Syracuse to Knoxville flights typically cost between $382 and $519 in October.
The cheapest round-trip price found within the last 5 days was $271 on Allegiant Air (Oct 4-Oct 10).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated August 10, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from Syracuse to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.8
Good
8,497 reviews

Crew

8.5

Overall

7.8

Comfort

7.8

Entertainment

7.8

Food

7.2

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Barney,May 2026

JFK - ATL

Terrible flight. Late, reduced beverage service, lack of headphones, entertainment service didn't work
Delta
7.8
Good
8,497 reviews
Delta
7.8
Good
8,497 reviews

Crew

8.5

Overall

7.8

Comfort

7.8

Entertainment

7.8

Food

7.2

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Barney,May 2026

JFK - ATL

Terrible flight. Late, reduced beverage service, lack of headphones, entertainment service didn't work
United Airlines
7.4
Good
10,095 reviews
Delta
7.8
Good
8,497 reviews

Crew

8.5

Overall

7.8

Comfort

7.8

Entertainment

7.8

Food

7.2

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Barney,May 2026

JFK - ATL

Terrible flight. Late, reduced beverage service, lack of headphones, entertainment service didn't work
American Airlines
7.1
Good
11,897 reviews
Delta
7.8
Good
8,497 reviews

Crew

8.5

Overall

7.8

Comfort

7.8

Entertainment

7.8

Food

7.2

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Barney,May 2026

JFK - ATL

Terrible flight. Late, reduced beverage service, lack of headphones, entertainment service didn't work

Related info for your journey

Find useful and relevant information for your journey from Syracuse to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Syracuse to Knoxville?

    For as low as $287, United Airlines can have you in Knoxville from Syracuse in 4h 04m. Syracuse and Knoxville are separated by a distance of 656 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Syracuse to Knoxville round-trip?

    Our cheapest airline available from Syracuse to Knoxville is American Airlines. Our recent data shows that you can find tickets from as low as $248 on this airline. Additional options worth looking into are Delta and United Airlines, starting at $253 and $262 round-trip. American Airlines is currently priced 37% below the average price you’ll pay for this route.

  • Can I find deals for flights from Syracuse to Knoxville that include hotel bookings?

    Yes. In addition to deals on Syracuse to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Knoxville.

  • Can I find deals for business class flights from Syracuse to Knoxville?

    Yes. Cheapflights offers flight deals from Syracuse to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Syracuse to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Syracuse to Knoxville (average of $260). Flying from Syracuse to Knoxville in May is currently the most expensive (average of $657). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 3 airlines flying from Syracuse to Knoxville

Discover the top 3 airlines that operate flights from Syracuse to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 10, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$391FlexibilityNo cancel feeOn-time71%
DeltaCheapest$253Average$357FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$262Average$412FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
Site
©2026 Cheapflights