$166+ Cheap flights from Syracuse to Knoxville (SYR - TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/16. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — TYS
Oct 21 — Oct 281
Round-trip
1 adult, Economy
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Find cheap flights from Syracuse to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Syracuse to Knoxville
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Last-minute
One-way
Cheapest flights from Syracuse to KnoxvilleExplore the most affordable flight options available from Syracuse to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 21, 2026.
Explore the most affordable flight options available from Syracuse to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 21, 2026.
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/204:35 pm -
1 stop6h 19m
Tue 10/276:20 am -
1 stop5h 59m
Deal found 9/17![American Airlines logo]()
$307
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:08 am -
1 stop4h 54m
Sat 10/245:40 am -
1 stop5h 29m
Deal found 9/21![Delta logo]()
$323
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/412:20 pm -
1 stop5h 10m
Mon 12/75:27 pm -
1 stop5h 34m
Deal found 9/20![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:00 am -
1 stop4h 37m
Mon 10/267:35 pm -
1 stop4h 08m
Deal found 9/19![United Airlines logo]()
$348
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:00 am -
1 stop4h 20m
Fri 11/2011:00 am -
1 stop5h 35m
Deal found 9/18![Delta logo]()
$354
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:00 am -
1 stop4h 39m
Fri 11/206:50 am -
1 stop3h 59m
Deal found 9/17![American Airlines logo]()
$368
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:00 am -
1 stop6h 51m
Wed 10/75:18 pm -
1 stop6h 00m
Deal found 9/19![Delta logo]()
$369
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:38 pm -
1 stop13h 37m
Wed 10/74:14 pm -
1 stop17h 34m
Deal found 9/19![Allegiant Air logo]()
$372
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:07 am -
1 stop7h 07m
Wed 10/76:00 am -
2 stops8h 19m
Deal found 9/19![United Airlines logo]()
$374
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:00 am -
1 stop4h 37m
Sat 10/107:25 pm -
1 stop4h 21m
Deal found 9/17![United Airlines logo]()
$375
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:00 am -
1 stop5h 06m
Wed 10/77:26 am -
1 stop5h 35m
Deal found 9/19![Delta logo]()
$376
Best flights from Syracuse to KnoxvilleDiscover carefully curated flight deals from Syracuse to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 21, 2026.
Discover carefully curated flight deals from Syracuse to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 21, 2026.
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/141:25 pm -
1 stop6h 40m
Fri 11/2012:34 pm -
1 stop5h 29m
Deal found 9/16![Delta logo]()
$323
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:00 am -
1 stop4h 37m
Sat 10/104:16 pm -
2 stops7h 30m
Deal found 9/17![United Airlines logo]()
$381
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:08 am -
1 stop4h 54m
Sat 10/245:40 am -
1 stop5h 29m
Deal found 9/21![Delta logo]()
$323
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/412:20 pm -
1 stop5h 10m
Mon 12/75:27 pm -
1 stop5h 34m
Deal found 9/20![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:53 pm -
1 stop4h 06m
Tue 10/274:30 pm -
2 stops7h 13m
Deal found 9/17![United Airlines logo]()
$392
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:22 am -
1 stop3h 58m
Sat 10/101:40 pm -
1 stop7h 25m
Deal found 9/17![Delta logo]()
$354
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:35 pm -
1 stop4h 24m
Sat 11/71:56 pm -
2 stops9h 47m
Deal found 9/20![United Airlines logo]()
$428
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:00 am -
1 stop6h 51m
Wed 10/75:18 pm -
1 stop6h 00m
Deal found 9/19![Delta logo]()
$369
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:00 am -
1 stop4h 37m
Tue 10/274:30 pm -
2 stops7h 13m
Deal found 9/19![United Airlines logo]()
$492
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:59 pm -
1 stop4h 56m
Tue 10/65:40 am -
1 stop5h 29m
Deal found 9/19![Delta logo]()
$494
Last-minute flights from Syracuse to KnoxvilleDiscover last-minute flight deals from Syracuse to Knoxville. Data last updated September 21, 2026 and is based on user searches.
Discover last-minute flight deals from Syracuse to Knoxville. Data last updated September 21, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:00 am -
1 stop5h 06m
Wed 10/77:26 am -
1 stop5h 35m
Deal found 9/19![Delta logo]()
$376
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:38 pm -
1 stop13h 37m
Wed 10/74:14 pm -
1 stop17h 34m
Deal found 9/19![Allegiant Air logo]()
$372
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:00 am -
1 stop6h 51m
Wed 10/75:18 pm -
1 stop6h 00m
Deal found 9/19![Delta logo]()
$369
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:07 am -
1 stop7h 07m
Wed 10/76:00 am -
2 stops8h 19m
Deal found 9/19![United Airlines logo]()
$374
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:22 am -
1 stop3h 58m
Sat 10/101:40 pm -
1 stop7h 25m
Deal found 9/17![Delta logo]()
$354
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:00 am -
1 stop4h 37m
Sat 10/107:25 pm -
1 stop4h 21m
Deal found 9/17![United Airlines logo]()
$375
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:08 am -
1 stop4h 54m
Sat 10/245:40 am -
1 stop5h 29m
Deal found 9/21![Delta logo]()
$323
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/204:35 pm -
1 stop6h 19m
Tue 10/276:20 am -
1 stop5h 59m
Deal found 9/17![American Airlines logo]()
$307
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:00 am -
1 stop4h 37m
Mon 10/267:35 pm -
1 stop4h 08m
Deal found 9/19![United Airlines logo]()
$348
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:08 am -
1 stop4h 54m
Mon 10/265:15 pm -
1 stop5h 42m
Deal found 9/19![Delta logo]()
$339
One-way flights from Syracuse to KnoxvilleSearch for one-way flight options from Syracuse to Knoxville. Find affordable one-way fares based on user searches. Data last updated September 21, 2026.
Search for one-way flight options from Syracuse to Knoxville. Find affordable one-way fares based on user searches. Data last updated September 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:52 pm -
1 stop17h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Allegiant Air logo]()
$166
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/172:43 pm -
1 stop24h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Allegiant Air logo]()
$179
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/226:36 pm -
1 stop14h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Allegiant Air logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/183:20 pm -
3 stops28h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Multiple Airlines logo]()
$215
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/249:47 am -
1 stop25h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Allegiant Air logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2210:11 pm -
2 stops25h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Multiple Airlines logo]()
$257
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/103:20 pm -
3 stops32h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Multiple Airlines logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/289:21 pm -
2 stops41h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Multiple Airlines logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/211:57 pm -
2 stops32h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Multiple Airlines logo]()
$279
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:08 am -
1 stop4h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Delta logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/181:44 pm -
2 stops29h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Allegiant Air logo]()
$295
Find flight deals from Syracuse to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Syracuse (SYR) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $307 (American Airlines) |
One-way from | $166 (Kiwi.com) |
Popular in | May |
Cheapest in | January |
Average price | $318 |
Cheapflights Fare Finder
Customize your flight search to find flights from Syracuse to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 21, 2026.
Use the filters below to find and compare flights from Syracuse to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
SyracuseKnoxville
SYR Syracuse Hancock Intl - TYS Knoxville McGhee Tyson
SYRTYS
Syracuse Hancock Intl
Thu 11/19
6:36 pm-8:39 am
1 stop14h 03m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$271
SyracuseKnoxville
SYR Syracuse Hancock Intl - TYS Knoxville McGhee Tyson
SYRTYS
Syracuse Hancock Intl
Sat 11/14
1:25 pm-8:05 pm
1 stop6h 40m
Knoxville McGhee Tyson
Fri 11/20
12:34 pm-6:03 pm
1 stop5h 29m
$323
SyracuseKnoxville
SYR Syracuse Hancock Intl - TYS Knoxville McGhee Tyson
SYRTYS
Syracuse Hancock Intl
Mon 10/19
6:08 am-11:02 am
1 stop4h 54m
Knoxville McGhee Tyson
Sat 10/24
5:40 am-11:09 am
1 stop5h 29m
$323
SyracuseKnoxville
SYR Syracuse Hancock Intl - TYS Knoxville McGhee Tyson
SYRTYS
Syracuse Hancock Intl
Tue 11/17
10:17 am-8:54 pm
2 stops10h 37m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$328
SyracuseKnoxville
SYR Syracuse Hancock Intl - TYS Knoxville McGhee Tyson
SYRTYS
Syracuse Hancock Intl
Fri 12/4
12:20 pm-5:30 pm
1 stop5h 10m
Knoxville McGhee Tyson
Mon 12/7
5:27 pm-11:01 pm
1 stop5h 34m
$339
SyracuseKnoxville
SYR Syracuse Hancock Intl - TYS Knoxville McGhee Tyson
SYRTYS
Syracuse Hancock Intl
Wed 10/7
6:22 am-10:20 am
1 stop3h 58m
Knoxville McGhee Tyson
Sat 10/10
1:40 pm-9:05 pm
1 stop7h 25m
$354
SyracuseKnoxville
SYR Syracuse Hancock Intl - TYS Knoxville McGhee Tyson
SYRTYS
Syracuse Hancock Intl
Mon 11/16
11:15 am-6:44 pm
2 stops7h 29m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$358
SyracuseKnoxville
SYR Syracuse Hancock Intl - TYS Knoxville McGhee Tyson
SYRTYS
Syracuse Hancock Intl
Sat 10/3
6:00 am-12:51 pm
1 stop6h 51m
Knoxville McGhee Tyson
Wed 10/7
5:18 pm-11:18 pm
1 stop6h 00m
$369
SyracuseKnoxville
SYR Syracuse Hancock Intl - TYS Knoxville McGhee Tyson
SYRTYS
Syracuse Hancock Intl
Sun 10/4
6:10 am-1:21 pm
1 stop7h 11m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$379
Quickest round-trip
SyracuseKnoxville
SYR Syracuse Hancock Intl - TYS Knoxville McGhee Tyson
SYRTYS
Syracuse Hancock Intl
Sun 10/4
6:00 am-11:05 am
1 stop5h 05m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$379
Showing 1-10 of 16 resultsSorted by cheapest first
Compare providers for flights from Syracuse to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Syracuse to Knoxville in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Syracuse-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Syracuse-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Syracuse-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Syracuse-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Syracuse-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Syracuse to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Syracuse with our price prediction graph.
SYR-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Syracuse to Knoxville
How far ahead should I book a flight from Syracuse to Knoxville?
Booking 56 days in advance of your planned departure date is, on average, the best time to get cheap flights from Syracuse to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Syracuse to Knoxville?
Currently, January is the cheapest month in which you can book a flight from Syracuse to Knoxville (average of $260). Flying from Syracuse to Knoxville in May is currently the most expensive (average of $657). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Syracuse to Knoxville?
Airfare is typical for this route at the moment.
Syracuse to Knoxville flights typically cost between $304 and $446 in October.The cheapest round-trip price found within the last 5 days was $307 on American Airlines (Oct 20-Oct 27).
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated September 21, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from Syracuse to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Overall
7.8
Entertainment
7.8
Food
7.2
Comfort
7.8
Crew
8.5
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Boarding
8.1
Overall
7.8
Entertainment
7.8
Food
7.2
Comfort
7.8
Crew
8.5
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Boarding
8.1
Overall
7.8
Entertainment
7.8
Food
7.2
Comfort
7.8
Crew
8.5
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Boarding
8.1
Overall
7.8
Entertainment
7.8
Food
7.2
Comfort
7.8
Crew
8.5
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Related info for your journey
Find useful and relevant information for your journey from Syracuse to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
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Top 3 airlines flying from Syracuse to Knoxville
Discover the top 3 airlines that operate flights from Syracuse to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$253 | Average$362 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$259 | Average$397 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$309 | Average$412 | FlexibilityNo cancel fee | On-time69% |