$179+ Cheap flights from Knoxville to Syracuse (TYS - SYR)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/1. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — SYR
Oct 9 — Oct 161
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Knoxville to Syracuse with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Syracuse
Cheapest
Best
Last-minute
One-way
Cheapest flights from Knoxville to SyracuseExplore the most affordable flight options available from Knoxville to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
Explore the most affordable flight options available from Knoxville to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/74:49 pm -
1 stop5h 51m
Wed 10/146:00 am -
1 stop4h 25m
Deal found 9/7![American Airlines logo]()
$287
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:05 pm -
1 stop5h 24m
Wed 10/146:00 am -
1 stop4h 25m
Deal found 9/5![American Airlines logo]()
$303
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:18 pm -
1 stop6h 00m
Tue 10/136:08 am -
1 stop4h 54m
Deal found 9/7![Delta logo]()
$307
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1510:00 am -
1 stop5h 38m
Mon 10/197:43 pm -
1 stop4h 12m
Deal found 9/4![American Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:18 pm -
1 stop6h 00m
Sun 10/186:22 am -
1 stop3h 58m
Deal found 9/7![Delta logo]()
$323
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/193:53 pm -
1 stop4h 37m
Sat 9/261:15 pm -
1 stop6h 46m
Deal found 9/5![American Airlines logo]()
$334
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:40 am -
1 stop5h 29m
Mon 10/196:08 am -
1 stop4h 54m
Deal found 9/7![Delta logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:55 pm -
1 stop15h 09m
Mon 9/289:21 pm -
2 stops41h 21m
Deal found 9/4![Multiple Airlines logo]()
$346
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:15 am -
1 stop6h 19m
Sat 9/261:15 pm -
1 stop6h 46m
Deal found 9/7![American Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/267:25 pm -
1 stop4h 21m
Mon 9/287:53 pm -
1 stop4h 06m
Deal found 9/4![United Airlines logo]()
$354
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:00 am -
2 stops8h 14m
Sat 9/267:53 pm -
1 stop4h 06m
Deal found 9/5![United Airlines logo]()
$359
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/125:40 am -
1 stop5h 40m
Thu 10/16:00 am -
1 stop5h 04m
Deal found 9/7![Delta logo]()
$361
Best flights from Knoxville to SyracuseDiscover carefully curated flight deals from Knoxville to Syracuse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
Discover carefully curated flight deals from Knoxville to Syracuse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:45 am -
1 stop4h 03m
Mon 10/57:53 pm -
1 stop4h 06m
Deal found 9/4![United Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:23 pm -
1 stop5h 32m
Tue 10/136:08 am -
1 stop4h 54m
Deal found 9/7![Delta logo]()
$323
This Delta deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:00 am -
1 stop5h 31m
Tue 10/66:08 am -
1 stop4h 54m
Deal found 9/4![Delta logo]()
$323
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:00 am -
2 stops8h 14m
Sat 9/267:53 pm -
1 stop4h 06m
Deal found 9/5![United Airlines logo]()
$359
This Delta deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:15 pm -
1 stop5h 54m
Mon 10/56:00 am -
1 stop5h 04m
Deal found 9/4![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:18 pm -
1 stop6h 00m
Sun 10/186:22 am -
1 stop3h 58m
Deal found 9/5![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:00 am -
1 stop4h 43m
Thu 10/156:00 am -
2 stops9h 35m
Deal found 9/7![United Airlines logo]()
$424
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/226:10 am -
1 stop4h 59m
Sat 3/136:50 pm -
1 stop4h 56m
Deal found 9/6![Delta logo]()
$370
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:00 am -
2 stops8h 19m
Wed 10/146:00 am -
2 stops7h 14m
Deal found 9/7![United Airlines logo]()
$468
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:28 pm -
1 stop5h 30m
Sat 10/176:22 am -
1 stop4h 17m
Deal found 9/7![Delta logo]()
$408
Last-minute flights from Knoxville to SyracuseDiscover last-minute flight deals from Knoxville to Syracuse. Data last updated September 9, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Syracuse. Data last updated September 9, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/125:40 am -
1 stop5h 40m
Thu 10/16:00 am -
1 stop5h 04m
Deal found 9/7![Delta logo]()
$361
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/193:53 pm -
1 stop4h 37m
Sat 9/261:15 pm -
1 stop6h 46m
Deal found 9/5![American Airlines logo]()
$334
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:00 am -
2 stops8h 14m
Sat 9/267:53 pm -
1 stop4h 06m
Deal found 9/5![United Airlines logo]()
$359
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:15 am -
1 stop6h 19m
Sat 9/261:15 pm -
1 stop6h 46m
Deal found 9/7![American Airlines logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:55 pm -
1 stop15h 09m
Mon 9/289:21 pm -
2 stops41h 21m
Deal found 9/4![Multiple Airlines logo]()
$346
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/267:25 pm -
1 stop4h 21m
Mon 9/287:53 pm -
1 stop4h 06m
Deal found 9/4![United Airlines logo]()
$354
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:05 pm -
1 stop5h 24m
Wed 10/146:00 am -
1 stop4h 25m
Deal found 9/5![American Airlines logo]()
$303
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/74:49 pm -
1 stop5h 51m
Wed 10/146:00 am -
1 stop4h 25m
Deal found 9/7![American Airlines logo]()
$287
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:18 pm -
1 stop6h 00m
Tue 10/136:08 am -
1 stop4h 54m
Deal found 9/7![Delta logo]()
$307
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:18 pm -
1 stop6h 00m
Sun 10/186:22 am -
1 stop3h 58m
Deal found 9/7![Delta logo]()
$323
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1510:00 am -
1 stop5h 38m
Mon 10/197:43 pm -
1 stop4h 12m
Deal found 9/4![American Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:40 am -
1 stop5h 29m
Mon 10/196:08 am -
1 stop4h 54m
Deal found 9/7![Delta logo]()
$339
One-way flights from Knoxville to SyracuseSearch for one-way flight options from Knoxville to Syracuse. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
Search for one-way flight options from Knoxville to Syracuse. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:15 am -
1 stop11h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Allegiant Air logo]()
$179
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/294:09 pm -
2 stops22h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Multiple Airlines logo]()
$181
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/139:00 am -
3 stops57h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Multiple Airlines logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/304:14 pm -
1 stop25h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Allegiant Air logo]()
$188
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/39:36 pm -
1 stop13h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Allegiant Air logo]()
$195
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:43 pm -
1 stop24h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Multiple Airlines logo]()
$197
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:30 am -
1 stop9h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Allegiant Air logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:39 pm -
3 stops49h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$256
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:04 pm -
3 stops43h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Multiple Airlines logo]()
$260
Find flight deals from Knoxville to Syracuse
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Syracuse (SYR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $287 (American Airlines) |
One-way from | $179 (Kiwi.com) |
Popular in | February |
Cheapest in | December |
Average price | $338 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Syracuse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
Use the filters below to find and compare flights from Knoxville to Syracuse that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleSyracuse
TYS Knoxville McGhee Tyson - SYR Syracuse Hancock Intl
TYSSYR
Knoxville McGhee Tyson
Wed 9/30
4:14 pm-5:48 pm
1 stop25h 34m
Syracuse Hancock Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$188
KnoxvilleSyracuse
TYS Knoxville McGhee Tyson - SYR Syracuse Hancock Intl
TYSSYR
Knoxville McGhee Tyson
Sat 10/3
9:36 pm-10:38 am
1 stop13h 02m
Syracuse Hancock Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$195
KnoxvilleSyracuse
TYS Knoxville McGhee Tyson - SYR Syracuse Hancock Intl
TYSSYR
Knoxville McGhee Tyson
Sat 10/3
9:36 pm-6:49 pm
2 stops21h 13m
Syracuse Hancock Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$230
KnoxvilleSyracuse
TYS Knoxville McGhee Tyson - SYR Syracuse Hancock Intl
TYSSYR
Knoxville McGhee Tyson
Fri 10/2
5:39 pm-6:49 pm
3 stops49h 10m
Syracuse Hancock Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$256
KnoxvilleSyracuse
TYS Knoxville McGhee Tyson - SYR Syracuse Hancock Intl
TYSSYR
Knoxville McGhee Tyson
Mon 9/28
7:04 pm-2:40 pm
3 stops43h 36m
Syracuse Hancock Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$260
KnoxvilleSyracuse
TYS Knoxville McGhee Tyson - SYR Syracuse Hancock Intl
TYSSYR
Knoxville McGhee Tyson
Thu 10/1
6:00 am-2:19 pm
2 stops8h 19m
Syracuse Hancock Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$279
KnoxvilleSyracuse
TYS Knoxville McGhee Tyson - SYR Syracuse Hancock Intl
TYSSYR
Knoxville McGhee Tyson
Tue 10/13
6:00 am-11:27 am
1 stop5h 27m
Syracuse Hancock Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$284
Quickest round-trip
KnoxvilleSyracuse
TYS Knoxville McGhee Tyson - SYR Syracuse Hancock Intl
TYSSYR
Knoxville McGhee Tyson
Fri 10/2
6:00 am-10:43 am
1 stop4h 43m
Syracuse Hancock Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$284
KnoxvilleSyracuse
TYS Knoxville McGhee Tyson - SYR Syracuse Hancock Intl
TYSSYR
Knoxville McGhee Tyson
Fri 10/2
7:13 pm-10:38 am
2 stops39h 25m
Syracuse Hancock Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$285
KnoxvilleSyracuse
TYS Knoxville McGhee Tyson - SYR Syracuse Hancock Intl
TYSSYR
Knoxville McGhee Tyson
Sat 10/3
10:42 am-11:46 pm
2 stops13h 04m
Syracuse Hancock Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$319
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from Knoxville to Syracuse
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Syracuse in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-Syracuse flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Syracuse flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Syracuse flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Syracuse flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Syracuse flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Syracuse
Have a flexible travel schedule? Discover the best time to fly to Syracuse from Knoxville with our price prediction graph.
TYS-SYR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Syracuse
What is the cheapest month to book a flight from Knoxville to Syracuse?
Currently, December is the cheapest month in which you can book a flight from Knoxville to Syracuse (average of $248). Flying from Knoxville to Syracuse in February is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Knoxville to Syracuse?
Airfare is below average for this route at the moment.
Knoxville to Syracuse flights typically cost between $293 and $558 in October.The cheapest round-trip price found within the last 5 days was $287 on American Airlines (Oct 7-Oct 14).
Reviews of airlines servicing Syracuse
Get insights into the airlines that provide service to Syracuse. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Syracuse. Reviews last updated September 9, 2026.
Read reviews from past customers who have flown Delta and American Airlines from Knoxville to Syracuse. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Boarding
8.1
Overall
7.8
Comfort
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentLucy,Nov 2023
ATL - JFK
Entertainment
7.8
Boarding
8.1
Overall
7.8
Comfort
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentLucy,Nov 2023
ATL - JFK
Entertainment
7.8
Boarding
8.1
Overall
7.8
Comfort
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentLucy,Nov 2023
ATL - JFK
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Syracuse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Syracuse?
Book flights to Syracuse if you plan to visit one of these locationsEast Syracuse
Liverpool
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Knoxville
Popular flights
Syracuse flight routes
Alternative routes for Knoxville to Syracuse
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Syracuse by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Knoxville to Syracuse by cabin class
Find flights from Knoxville to Syracuse, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Knoxville and Syracuse flights
Browse other Knoxville and Syracuse flight options. Last updated on September 9, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on September 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Syracuse
Explore flights to Syracuse departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 9, 2026.
Top 2 airlines flying from Knoxville to Syracuse
Discover the top 2 airlines that operate flights from Knoxville to Syracuse. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$355 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$248 | Average$328 | FlexibilityNo cancel fee | On-timeN/A |