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Syracuse

$228+ Cheap flights from Knoxville to Syracuse (TYS - SYR)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/18. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — SYR
Jul 16 — Jul 231
Wed 7/16
Wed 7/23
1 adult, Economy
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Cheap flight deals from Knoxville to Syracuse

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Syracuse (SYR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 11, 2025.

Round-trip from

$244
(Mytrip)

One-way from

$228
(Mytrip)

Popular in

December

Cheapest in

September

Average price

$355
From Knoxville McGhee Tyson to Syracuse Hancock Intl
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One-way flight from Knoxville McGhee Tyson to Syracuse Hancock Intl
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Highest demand for flights based on searches. 15% potential increase in price ($57 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Knoxville to Syracuse

Cheapest flights from Knoxville to Syracuse
Explore the most affordable flight options available from Knoxville to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 11, 2025.

This Mytrip deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/277:44 pmTYS - SYR
1 stop13h 12mAllegiant Air
Thu 7/319:36 amSYR - TYS
1 stop13h 20mAllegiant Air
Deal found 7/10$244
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/155:19 pmTYS - SYR
1 stop5h 49mDelta
Fri 8/296:20 amSYR - TYS
1 stop4h 25mDelta
Deal found 7/10$249
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/56:00 amTYS - SYR
2 stops7h 05mAmerican Airlines
Mon 9/86:49 pmSYR - TYS
1 stop4h 14mAmerican Airlines
Deal found 7/9$284
This Mytrip deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/153:34 pmTYS - SYR
2 stops21h 31mMultiple Airlines
Sun 8/246:05 pmSYR - TYS
2 stops23h 33mMultiple Airlines
Deal found 7/10$312
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2110:54 amTYS - SYR
2 stops12h 15mUnited Airlines
Wed 8/277:48 pmSYR - TYS
1 stop4h 09mUnited Airlines
Deal found 7/9$383

Cheapflights Fare Finder

Customize your flight search to find flights from Knoxville to Syracuse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 11, 2025.
Use the filters below to find and compare flights from Knoxville to Syracuse that are best for you.

Fly from

Knoxville

Fly to

Syracuse

Route

Depart

Return

Price

KnoxvilleSyracuse

TYS - SYR

TYSSYR

Knoxville McGhee Tyson

Sun 7/27

7:44 pm-8:56 am

1 stop13h 12m

Syracuse Hancock Intl

Thu 7/31

9:36 am-10:56 pm

1 stop13h 20m

$244

KnoxvilleSyracuse

TYS - SYR

TYSSYR

Knoxville McGhee Tyson

Fri 8/15

5:19 pm-11:08 pm

1 stop5h 49m

Syracuse Hancock Intl

Fri 8/29

6:20 am-10:45 am

1 stop4h 25m

$249

KnoxvilleSyracuse

TYS - SYR

TYSSYR

Knoxville McGhee Tyson

Fri 9/5

6:00 am-1:05 pm

2 stops7h 05m

Syracuse Hancock Intl

Mon 9/8

6:49 pm-11:03 pm

1 stop4h 14m

$284

KnoxvilleSyracuse

TYS - SYR

TYSSYR

Knoxville McGhee Tyson

Fri 8/15

3:34 pm-1:05 pm

2 stops21h 31m

Syracuse Hancock Intl

Sun 8/24

6:05 pm-5:38 pm

2 stops23h 33m

$312

KnoxvilleSyracuse

TYS - SYR

TYSSYR

Knoxville McGhee Tyson

Thu 8/21

10:54 am-11:09 pm

2 stops12h 15m

Syracuse Hancock Intl

Wed 8/27

7:48 pm-11:57 pm

1 stop4h 09m

$383

KnoxvilleSyracuse

TYS - SYR

TYSSYR

Knoxville McGhee Tyson

Fri 7/18

9:02 am-7:01 pm

1 stop9h 59m

$228

KnoxvilleSyracuse

TYS - SYR

TYSSYR

Knoxville McGhee Tyson

Fri 7/18

6:00 am-9:33 am

2 stops27h 33m

$245

KnoxvilleSyracuse

TYS - SYR

TYSSYR

Knoxville McGhee Tyson

Thu 7/17

5:25 pm-11:53 am

2 stops18h 28m

$295

KnoxvilleSyracuse

TYS - SYR

TYSSYR

Knoxville McGhee Tyson

Thu 7/17

1:54 pm-7:40 pm

1 stop5h 46m

$375

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/10

Best time to book a flight from Knoxville to Syracuse

Have a flexible travel schedule? Discover the best time to fly to Syracuse from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Syracuse

What is the cheapest month to book a flight from Knoxville to Syracuse?

Currently, January is the cheapest month in which you can book a flight from Knoxville to Syracuse (average of $272). Flying from Knoxville to Syracuse in July is currently the most expensive (average of $384). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to SYR?

Find hourly flight availability from Knoxville to Syracuse. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 11, 2025.

It’s typically best to fly out from Knoxville to Syracuse in the morning. Doing so could potentially save you 24% on the flight price compared to flying at noon, which is usually more expensive.

Reviews of airlines servicing Syracuse

Get insights into the airlines that provide service to Syracuse. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Syracuse. Reviews last updated July 11, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Knoxville to Syracuse. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,951 reviews

Crew

8.5

Food

7.3

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!
Delta
8.0
Very good
7,951 reviews
Delta
8.0
Very good
7,951 reviews

Crew

8.5

Food

7.3

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!
United Airlines
7.4
Good
8,846 reviews
Delta
8.0
Very good
7,951 reviews

Crew

8.5

Food

7.3

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,951 reviews

Crew

8.5

Food

7.3

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!
Allegiant Air
7.2
Good
704 reviews
Delta
8.0
Very good
7,951 reviews

Crew

8.5

Food

7.3

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!
Frontier
5.9
Fair
3,271 reviews
Delta
8.0
Very good
7,951 reviews

Crew

8.5

Food

7.3

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Syracuse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Knoxville to Syracuse round-trip?

    According to our current data, Allegiant Air ($244), Delta ($249), and American Airlines ($284) offers the cheapest pricing from Knoxville to Syracuse. You may be able to fly from Knoxville to Syracuse for 24% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Knoxville to Syracuse one-way?

    The cheapest airline one-way is Allegiant Air, with whom users have recently found tickets for as low as $228. However, be on the lookout for offers from Frontier and American Airlines, as they are both options that can get you from Knoxville to Syracuse for a low price.

  • Can I find deals for flights from Knoxville to Syracuse that include hotel bookings?

    Yes. In addition to deals on Knoxville to Syracuse flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Syracuse?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Syracuse.

  • Can I find deals for business class flights from Knoxville to Syracuse?

    Yes. Cheapflights offers flight deals from Knoxville to Syracuse by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Syracuse?

    Currently, January is the cheapest month in which you can book a flight from Knoxville to Syracuse (average of $272). Flying from Knoxville to Syracuse in July is currently the most expensive (average of $384). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Auburn
Liverpool
Cicero
East Syracuse
Waterloo

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Top 3 airlines flying from Knoxville to Syracuse

Discover the top 3 airlines that operate flights from Knoxville to Syracuse. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$212Average$314FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$223Average$413FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$228Average$346FlexibilityNo cancel feeOn-time71%

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