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Syracuse

$132+ Cheap flights from Knoxville to Syracuse (TYS - SYR)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/31. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — SYR
Jul 28 — Aug 41
Tue 7/28
Tue 8/4
1 adult, Economy
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Cheap flight deals from Knoxville to Syracuse

Cheapest flights from Knoxville to Syracuse
Explore the most affordable flight options available from Knoxville to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 28, 2026.

This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/67:45 am
TYS
-
SYR
1 stop10h 51m
Allegiant Air
Sun 8/97:26 pm
SYR
-
TYS
1 stop13h 10m
Allegiant Air
Deal found 6/23$241
This Kiwi.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/143:11 pm
TYS
-
SYR
1 stop19h 16m
Allegiant Air
Sun 8/167:26 pm
SYR
-
TYS
1 stop13h 10m
Allegiant Air
Deal found 6/25$248
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/297:04 am
TYS
-
SYR
1 stop4h 47m
American Airlines
Wed 9/210:51 am
SYR
-
TYS
1 stop7h 13m
American Airlines
Deal found 6/25$277
This United Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/297:20 pm
TYS
-
SYR
1 stop4h 26m
United Airlines
Wed 9/210:25 am
SYR
-
TYS
2 stops10h 28m
United Airlines
Deal found 6/25$282
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/247:16 pm
TYS
-
SYR
1 stop5h 04m
American Airlines
Tue 7/287:34 pm
SYR
-
TYS
1 stop4h 17m
American Airlines
Deal found 6/25$293
This Kiwi.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/237:15 am
TYS
-
SYR
1 stop11h 21m
Allegiant Air
Wed 7/294:57 pm
SYR
-
TYS
1 stop21h 51m
Allegiant Air
Deal found 6/25$301
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1410:05 am
TYS
-
SYR
1 stop4h 06m
Delta
Sun 10/186:00 am
SYR
-
TYS
1 stop7h 23m
Delta
Deal found 6/23$308
This Delta deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:00 am
TYS
-
SYR
1 stop5h 36m
Delta
Mon 8/107:17 pm
SYR
-
TYS
1 stop4h 35m
Delta
Deal found 6/24$309
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/149:00 am
TYS
-
SYR
1 stop7h 55m
Allegiant Air
Thu 9/1710:54 am
SYR
-
TYS
1 stop23h 10m
Allegiant Air
Deal found 6/23$310
This Kiwi.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/147:30 am
TYS
-
SYR
2 stops11h 52m
Multiple Airlines
Sun 8/167:26 pm
SYR
-
TYS
1 stop13h 10m
Multiple Airlines
Deal found 6/25$323
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/105:35 pm
TYS
-
SYR
1 stop5h 37m
Delta
Mon 7/136:54 pm
SYR
-
TYS
1 stop4h 58m
Delta
Deal found 6/23$339

Find flight deals from Knoxville to Syracuse

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Syracuse (SYR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$241
(Kiwi.com)

One-way from

$132
(Kiwi.com)

Popular in

February

Cheapest in

December

Average price

$292
Provider with most accurate pricing for Knoxville McGhee Tyson-Syracuse Hancock Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Syracuse Hancock Intl flights.
Search Deals
From Knoxville McGhee Tyson to Syracuse Hancock Intl
Search Deals
One-way flight from Knoxville McGhee Tyson to Syracuse Hancock Intl
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($80 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Syracuse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 28, 2026.
Use the filters below to find and compare flights from Knoxville to Syracuse that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleSyracuse

TYS - SYR

TYSSYR

Knoxville McGhee Tyson

Thu 8/6

7:45 am-6:36 pm

1 stop10h 51m

Syracuse Hancock Intl

Sun 8/9

7:26 pm-8:36 am

1 stop13h 10m

$241

KnoxvilleSyracuse

TYS - SYR

TYSSYR

Knoxville McGhee Tyson

Fri 8/28

5:15 pm-11:17 pm

1 stop6h 02m

Syracuse Hancock Intl

Mon 8/31

6:00 am-10:58 am

1 stop4h 58m

$309

KnoxvilleSyracuse

TYS - SYR

TYSSYR

Knoxville McGhee Tyson

Fri 7/10

5:35 pm-11:12 pm

1 stop5h 37m

Syracuse Hancock Intl

Sat 7/18

6:10 am-10:49 am

1 stop4h 39m

$324
Quickest round-trip

KnoxvilleSyracuse

TYS - SYR

TYSSYR

Knoxville McGhee Tyson

Wed 10/14

10:05 am-2:11 pm

1 stop4h 06m

Syracuse Hancock Intl

Sun 10/18

6:00 am-11:06 am

1 stop5h 06m

$324

KnoxvilleSyracuse

TYS - SYR

TYSSYR

Knoxville McGhee Tyson

Thu 7/9

4:07 pm-10:53 pm

1 stop6h 46m

Syracuse Hancock Intl

Mon 7/13

7:34 pm-11:51 pm

1 stop4h 17m

$339

KnoxvilleSyracuse

TYS - SYR

TYSSYR

Knoxville McGhee Tyson

Fri 7/10

5:35 pm-11:12 pm

1 stop5h 37m

Syracuse Hancock Intl

Mon 7/13

6:54 pm-11:52 pm

1 stop4h 58m

$339

KnoxvilleSyracuse

TYS - SYR

TYSSYR

Knoxville McGhee Tyson

Sat 7/25

6:42 pm-9:48 am

1 stop15h 06m

Syracuse Hancock Intl

Sat 8/1

6:25 pm-10:23 pm

1 stop27h 58m

$343

KnoxvilleSyracuse

TYS - SYR

TYSSYR

Knoxville McGhee Tyson

Wed 9/9

9:45 am-2:14 pm

1 stop4h 29m

Syracuse Hancock Intl

Tue 9/15

5:48 pm-12:23 am

1 stop6h 35m

$357

KnoxvilleSyracuse

TYS - SYR

TYSSYR

Knoxville McGhee Tyson

Sat 8/8

4:15 pm-9:30 pm

1 stop5h 15m

Syracuse Hancock Intl

Wed 8/12

7:17 pm-11:54 pm

1 stop4h 37m

$362

KnoxvilleSyracuse

TYS - SYR

TYSSYR

Knoxville McGhee Tyson

Tue 7/7

7:19 pm-11:59 pm

1 stop4h 40m

Syracuse Hancock Intl

Sun 7/12

6:00 am-10:42 am

1 stop4h 42m

$392

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/26

Showing 1-10 of 19 resultsSorted by cheapest first
1
2

Compare providers for flights from Knoxville to Syracuse

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Syracuse in June.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Syracuse flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Syracuse flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Syracuse flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Syracuse flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Syracuse flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Syracuse

Have a flexible travel schedule? Discover the best time to fly to Syracuse from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Syracuse

What is the cheapest month to book a flight from Knoxville to Syracuse?

Currently, December is the cheapest month in which you can book a flight from Knoxville to Syracuse (average of $248). Flying from Knoxville to Syracuse in February is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Syracuse

Get insights into the airlines that provide service to Syracuse. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Syracuse. Reviews last updated June 28, 2026.
Read reviews from past customers who have flown Delta and American Airlines from Knoxville to Syracuse. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.8
Good
8,455 reviews

Boarding

8.1

Overall

7.8

Crew

8.5

Comfort

7.8

Entertainment

7.8

Food

7.2

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!
Delta
7.8
Good
8,455 reviews
Delta
7.8
Good
8,455 reviews

Boarding

8.1

Overall

7.8

Crew

8.5

Comfort

7.8

Entertainment

7.8

Food

7.2

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!
American Airlines
7.1
Good
11,776 reviews
Delta
7.8
Good
8,455 reviews

Boarding

8.1

Overall

7.8

Crew

8.5

Comfort

7.8

Entertainment

7.8

Food

7.2

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Syracuse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Syracuse?

    Airlines like Allegiant Air and Delta fly from Knoxville to Syracuse in about 6h 02m. The time it takes to get you to your destination can typically vary by up to 4h 49m. Knoxville and Syracuse are separated by a distance of 656 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Knoxville to Syracuse round-trip?

    According to our current data, American Airlines ($248), and Delta ($248) offers the cheapest pricing from Knoxville to Syracuse. You may be able to fly from Knoxville to Syracuse for 33% less than the average price by searching for these airlines.

  • Can I find deals for flights from Knoxville to Syracuse that include hotel bookings?

    Yes. In addition to deals on Knoxville to Syracuse flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Syracuse?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Syracuse.

  • Can I find deals for business class flights from Knoxville to Syracuse?

    Yes. Cheapflights offers flight deals from Knoxville to Syracuse by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Syracuse?

    Currently, December is the cheapest month in which you can book a flight from Knoxville to Syracuse (average of $248). Flying from Knoxville to Syracuse in February is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Syracuse?

Book flights to Syracuse if you plan to visit one of these locations
East Syracuse
Liverpool

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Top 2 airlines flying from Knoxville to Syracuse

Discover the top 2 airlines that operate flights from Knoxville to Syracuse. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$338FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$343FlexibilityNo cancel feeOn-timeN/A

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