Syracuse

$173+ Cheap flights from Knoxville to Syracuse (TYS - SYR)

TYS — SYR
Dec 9 — Dec 161
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1. Tell us where you want to go

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Cheap flight deals from Knoxville to Syracuse

Cheapest flights from Knoxville to Syracuse

Sat 12/127:00 am -
1 stop4h 15m
Mon 12/146:00 am -
1 stop5h 27m
Deal found 11/7$343
Sat 12/56:15 am -
2 stops7h 53m
Mon 12/77:50 pm -
1 stop4h 09m
Deal found 11/4$348
Thu 12/37:00 am -
1 stop4h 03m
Thu 12/106:00 am -
1 stop5h 20m
Deal found 11/5$349
Thu 11/195:45 am -
1 stop3h 57m
Mon 11/2310:17 am -
1 stop4h 31m
Deal found 11/4$369
Sat 11/211:56 pm -
1 stop7h 21m
Wed 11/255:40 am -
2 stops10h 12m
Deal found 11/6$384
Mon 11/235:40 am -
1 stop5h 41m
Fri 11/275:24 pm -
1 stop4h 48m
Deal found 11/7$399
Sat 12/1212:19 pm -
2 stops9h 03m
Mon 12/145:30 am -
1 stop5h 22m
Deal found 11/7$405
Thu 12/36:00 am -
2 stops8h 08m
Thu 12/107:50 pm -
1 stop4h 09m
Deal found 11/5$423
Fri 11/135:40 am -
1 stop5h 41m
Sun 11/156:00 am -
1 stop4h 20m
Deal found 11/6$439
Fri 11/136:45 am -
2 stops7h 27m
Sun 11/157:35 pm -
1 stop4h 24m
Deal found 11/6$444

Find flight deals from Knoxville to Syracuse

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$338
(Delta)

One-way from

$173
(Kiwi.com)

Popular in

February

Cheapest in

December

Average price

$363
Provider with most accurate pricing for Knoxville McGhee Tyson-Syracuse Hancock Intl flight deals.
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Syracuse Hancock Intl flights.
From Knoxville McGhee Tyson to Syracuse Hancock Intl
One-way flight from Knoxville McGhee Tyson to Syracuse Hancock Intl
Highest demand for flights based on searches. 11% potential increase in price ($51 potential increase over avg. RT price).
Cheapest flight prices on average. 4% potential price decrease ($16 potential savings vs. average RT price).
Average for round-trip flights in November 2026

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Knoxville to Syracuse that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleSyracuse

TYS Knoxville McGhee Tyson - SYR Syracuse Hancock Intl

TYSSYR

Knoxville McGhee Tyson

Tue 12/29

7:00 am-5:52 pm

1 stop10h 52m

Syracuse Hancock Intl

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$173

KnoxvilleSyracuse

TYS Knoxville McGhee Tyson - SYR Syracuse Hancock Intl

TYSSYR

Knoxville McGhee Tyson

Sun 11/22

6:10 am-5:46 pm

1 stop11h 36m

Syracuse Hancock Intl

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$242
Quickest round-trip

KnoxvilleSyracuse

TYS Knoxville McGhee Tyson - SYR Syracuse Hancock Intl

TYSSYR

Knoxville McGhee Tyson

Mon 12/28

8:00 am-12:19 pm

1 stop4h 19m

Syracuse Hancock Intl

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$289

KnoxvilleSyracuse

TYS Knoxville McGhee Tyson - SYR Syracuse Hancock Intl

TYSSYR

Knoxville McGhee Tyson

Tue 11/24

9:41 pm-4:47 pm

1 stop19h 06m

Syracuse Hancock Intl

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$329

KnoxvilleSyracuse

TYS Knoxville McGhee Tyson - SYR Syracuse Hancock Intl

TYSSYR

Knoxville McGhee Tyson

Tue 11/24

6:15 pm-11:17 am

2 stops41h 02m

Syracuse Hancock Intl

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$333

KnoxvilleSyracuse

TYS Knoxville McGhee Tyson - SYR Syracuse Hancock Intl

TYSSYR

Knoxville McGhee Tyson

Sun 11/22

9:54 pm-9:28 am

3 stops59h 34m

Syracuse Hancock Intl

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$334

KnoxvilleSyracuse

TYS Knoxville McGhee Tyson - SYR Syracuse Hancock Intl

TYSSYR

Knoxville McGhee Tyson

Sat 12/12

7:00 am-11:15 am

1 stop4h 15m

Syracuse Hancock Intl

Mon 12/14

6:00 am-11:27 am

1 stop5h 27m

$343

KnoxvilleSyracuse

TYS Knoxville McGhee Tyson - SYR Syracuse Hancock Intl

TYSSYR

Knoxville McGhee Tyson

Mon 2/22

12:35 pm-5:54 pm

1 stop5h 19m

Syracuse Hancock Intl

Sat 3/13

6:00 am-10:14 am

1 stop4h 14m

$343

KnoxvilleSyracuse

TYS Knoxville McGhee Tyson - SYR Syracuse Hancock Intl

TYSSYR

Knoxville McGhee Tyson

Sat 12/5

6:15 am-2:08 pm

2 stops7h 53m

Syracuse Hancock Intl

Mon 12/7

7:50 pm-11:59 pm

1 stop4h 09m

$348

KnoxvilleSyracuse

TYS Knoxville McGhee Tyson - SYR Syracuse Hancock Intl

TYSSYR

Knoxville McGhee Tyson

Sun 11/15

7:30 am-4:38 pm

2 stops33h 08m

Syracuse Hancock Intl

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$361

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/6

Showing 1-10 of 15 resultsSorted by cheapest first
1
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Compare providers for flights from Knoxville to Syracuse

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Syracuse in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Syracuse flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Syracuse flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Syracuse flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Syracuse flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Syracuse flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Syracuse

Have a flexible travel schedule? Discover the best time to fly to Syracuse from Knoxville with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Syracuse

What is the cheapest month to book a flight from Knoxville to Syracuse?

Currently, December is the cheapest month in which you can book a flight from Knoxville to Syracuse (average of $248). Flying from Knoxville to Syracuse in February is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Syracuse

Read reviews from past customers who have flown Delta,United Airlines, andAmerican Airlines from Knoxville to Syracuse. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

8.1

Overall

7.8

Food

7.2

Comfort

7.8

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
4.0
Okay

Jennifer,Sep 2026

ORD - LGA

The flight crew was 30 minutes late to an am flight and then that caused a delay

Boarding

8.1

Overall

7.8

Food

7.2

Comfort

7.8

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
4.0
Okay

Jennifer,Sep 2026

ORD - LGA

The flight crew was 30 minutes late to an am flight and then that caused a delay

Boarding

8.1

Overall

7.8

Food

7.2

Comfort

7.8

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
4.0
Okay

Jennifer,Sep 2026

ORD - LGA

The flight crew was 30 minutes late to an am flight and then that caused a delay

Boarding

8.1

Overall

7.8

Food

7.2

Comfort

7.8

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
4.0
Okay

Jennifer,Sep 2026

ORD - LGA

The flight crew was 30 minutes late to an am flight and then that caused a delay

Related info for your journey

  • How long is the flight from Knoxville to Syracuse?

    Airlines like Delta and United Airlines fly from Knoxville to Syracuse in about 4h 15m. The time it takes to get you to your destination can typically vary by up to 3h 38m. Knoxville and Syracuse are separated by a distance of 656 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Knoxville to Syracuse round-trip?

    According to our current data, American Airlines ($248), Delta ($268), and United Airlines ($287) offers the cheapest pricing from Knoxville to Syracuse. You may be able to fly from Knoxville to Syracuse for 38% less than the average price by searching for these airlines.

  • Can I find deals for flights from Knoxville to Syracuse that include hotel bookings?

    Yes. In addition to deals on Knoxville to Syracuse flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Syracuse?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Syracuse.

  • Can I find deals for business class flights from Knoxville to Syracuse?

    Yes. Cheapflights offers flight deals from Knoxville to Syracuse by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Syracuse?

    Currently, December is the cheapest month in which you can book a flight from Knoxville to Syracuse (average of $248). Flying from Knoxville to Syracuse in February is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Syracuse?

Book flights to Syracuse if you plan to visit one of these locations
East Syracuse
Auburn
Liverpool

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Top 3 airlines flying from Knoxville to Syracuse

AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$355FlexibilityNo cancel feeOn-time71%
DeltaCheapest$268Average$347FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$287Average$472FlexibilityNo cancel feeOn-time69%

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