$289+ Cheap flights from Knoxville to Islip, NY (TYS - ISP)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/25. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — ISP
Nov 24 — Dec 11
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Knoxville to Islip with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Islip
Cheapest
Best
Last-minute
One-way
Cheapest flights from Knoxville to IslipExplore the most affordable flight options available from Knoxville to Islip. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
Explore the most affordable flight options available from Knoxville to Islip. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/41:00 pm -
1 stop8h 15m
Sun 11/85:35 am -
2 stops11h 15m
Deal found 10/20![Southwest logo]()
$512
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:55 am -
1 stop3h 50m
Thu 11/265:45 am -
1 stop6h 45m
Deal found 10/22![Southwest logo]()
$527
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:30 am -
1 stop9h 15m
Mon 11/304:40 pm -
1 stop22h 12m
Deal found 10/20![Multiple Airlines logo]()
$549
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:30 am -
2 stops27h 47m
Sun 11/296:49 pm -
1 stop23h 07m
Deal found 10/24![Multiple Airlines logo]()
$719
This Southwest deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/218:55 am -
1 stop7h 30m
Sat 11/285:30 am -
2 stops9h 00m
Deal found 10/24![Southwest logo]()
$758
Best flights from Knoxville to IslipDiscover carefully curated flight deals from Knoxville to Islip that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
Discover carefully curated flight deals from Knoxville to Islip that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/41:00 pm -
1 stop8h 15m
Sun 11/85:35 am -
2 stops11h 15m
Deal found 10/20![Southwest logo]()
$512
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:55 am -
1 stop3h 50m
Thu 11/265:45 am -
2 stops9h 40m
Deal found 10/22![Southwest logo]()
$532
This Southwest deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:30 am -
2 stops9h 55m
Sat 11/285:30 am -
2 stops9h 00m
Deal found 10/24![Southwest logo]()
$763
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2412:40 pm -
1 stop11h 00m
Fri 11/275:35 am -
2 stops11h 15m
Deal found 10/22![Southwest logo]()
$838
This Southwest deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2412:40 pm -
1 stop11h 00m
Sat 11/285:30 am -
2 stops9h 00m
Deal found 10/24![Southwest logo]()
$868
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/247:15 pm -
2 stops13h 30m
Mon 11/306:05 am -
2 stops10h 55m
Deal found 10/20![Southwest logo]()
$875
This Southwest deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2512:40 pm -
2 stops11h 10m
Sun 11/295:25 am -
2 stops11h 25m
Deal found 10/24![Southwest logo]()
$1,033
Last-minute flights from Knoxville to IslipDiscover last-minute flight deals from Knoxville to Islip. Data last updated October 25, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Islip. Data last updated October 25, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/41:00 pm -
1 stop8h 15m
Sun 11/85:35 am -
2 stops11h 15m
Deal found 10/20![Southwest logo]()
$512
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:55 am -
1 stop3h 50m
Thu 11/265:45 am -
1 stop6h 45m
Deal found 10/22![Southwest logo]()
$527
This Southwest deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/218:55 am -
1 stop7h 30m
Sat 11/285:30 am -
2 stops9h 00m
Deal found 10/24![Southwest logo]()
$758
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:30 am -
1 stop9h 15m
Mon 11/304:40 pm -
1 stop22h 12m
Deal found 10/20![Multiple Airlines logo]()
$549
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:30 am -
2 stops27h 47m
Sun 11/296:49 pm -
1 stop23h 07m
Deal found 10/24![Multiple Airlines logo]()
$719
One-way flights from Knoxville to IslipSearch for one-way flight options from Knoxville to Islip. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
Search for one-way flight options from Knoxville to Islip. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2512:40 pm -
1 stop11h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Southwest logo]()
$289
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2412:40 pm -
1 stop11h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Southwest logo]()
$434
Find flight deals from Knoxville to Islip
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Islip (ISP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $512 (Southwest) |
One-way from | $289 (Southwest) |
Popular in | March |
Cheapest in | July |
Average price | $349 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Islip that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
Use the filters below to find and compare flights from Knoxville to Islip that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
KnoxvilleIslip
TYS Knoxville McGhee Tyson - ISP Islip Long Island
TYSISP
Knoxville McGhee Tyson
Wed 11/25
12:40 pm-11:40 pm
1 stop11h 00m
Islip Long Island
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$289
KnoxvilleIslip
TYS Knoxville McGhee Tyson - ISP Islip Long Island
TYSISP
Knoxville McGhee Tyson
Tue 11/24
12:40 pm-11:40 pm
1 stop11h 00m
Islip Long Island
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$434
KnoxvilleIslip
TYS Knoxville McGhee Tyson - ISP Islip Long Island
TYSISP
Knoxville McGhee Tyson
Wed 11/4
1:00 pm-9:15 pm
1 stop8h 15m
Islip Long Island
Sun 11/8
5:35 am-4:50 pm
2 stops11h 15m
$512
KnoxvilleIslip
TYS Knoxville McGhee Tyson - ISP Islip Long Island
TYSISP
Knoxville McGhee Tyson
Thu 11/19
7:55 am-11:45 am
1 stop3h 50m
Islip Long Island
Thu 11/26
5:45 am-3:25 pm
2 stops9h 40m
$532
KnoxvilleIslip
TYS Knoxville McGhee Tyson - ISP Islip Long Island
TYSISP
Knoxville McGhee Tyson
Sat 11/21
6:30 am-4:25 pm
2 stops9h 55m
Islip Long Island
Sat 11/28
5:30 am-2:30 pm
2 stops9h 00m
$763
KnoxvilleIslip
TYS Knoxville McGhee Tyson - ISP Islip Long Island
TYSISP
Knoxville McGhee Tyson
Tue 11/24
12:40 pm-11:40 pm
1 stop11h 00m
Islip Long Island
Fri 11/27
5:35 am-4:50 pm
2 stops11h 15m
$838
KnoxvilleIslip
TYS Knoxville McGhee Tyson - ISP Islip Long Island
TYSISP
Knoxville McGhee Tyson
Tue 11/24
12:40 pm-11:40 pm
1 stop11h 00m
Islip Long Island
Sat 11/28
5:30 am-2:30 pm
2 stops9h 00m
$868
KnoxvilleIslip
TYS Knoxville McGhee Tyson - ISP Islip Long Island
TYSISP
Knoxville McGhee Tyson
Tue 11/24
7:15 pm-8:45 am
2 stops13h 30m
Islip Long Island
Mon 11/30
6:05 am-5:00 pm
2 stops10h 55m
$875
KnoxvilleIslip
TYS Knoxville McGhee Tyson - ISP Islip Long Island
TYSISP
Knoxville McGhee Tyson
Wed 11/25
12:40 pm-11:50 pm
2 stops11h 10m
Islip Long Island
Sun 11/29
5:25 am-4:50 pm
2 stops11h 25m
$1,033
Sorted by cheapest first
Compare providers for flights from Knoxville to Islip
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Islip in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-Islip, New York flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Islip, New York flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Islip, New York flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Islip, New York flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Islip, New York flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Islip
Have a flexible travel schedule? Discover the best time to fly to Islip from Knoxville with our price prediction graph.
TYS-ISP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Islip
Get insights into the airlines that provide service to Islip. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Islip. Reviews last updated October 25, 2026.
Get a feel of what it's like to fly with Southwest from Knoxville to Islip by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.4
Overall
7.9
Food
7.0
Comfort
8.0
Crew
8.6
Boarding
8.1
Reviews
1 / 20
6.0
GoodSharilynn,May 2024
HOU - LGA
Entertainment
7.4
Overall
7.9
Food
7.0
Comfort
8.0
Crew
8.6
Boarding
8.1
Reviews
1 / 20
6.0
GoodSharilynn,May 2024
HOU - LGA
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Islip. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Islip?
Book flights to Islip if you plan to visit one of these locationsRiverhead
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Islip flight routes
Other flight options
Other flights from Knoxville
Popular flights
Alternative routes for Knoxville to Islip
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Islip by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Knoxville to Islip by cabin class
Find flights from Knoxville to Islip, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Islip
Explore flights to Islip departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 25, 2026.
Knoxville and Islip flights
Browse other Knoxville and Islip flight options. Last updated on October 25, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on October 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Knoxville to Islip
Discover the top airline that operate flights from Knoxville to Islip. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$317 | Average$423 | FlexibilityNo cancel fee | On-time63% |