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$155+ Cheap flights from Roanoke to Knoxville (ROA - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/19. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — TYS
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Roanoke to Knoxville

Cheapest flights from Roanoke to Knoxville
Explore the most affordable flight options available from Roanoke to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2510:15 am
ROA
-
TYS
1 stop5h 00m
United Airlines
Wed 3/49:40 am
TYS
-
ROA
1 stop4h 32m
United Airlines
Deal found 1/28$263
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/2910:15 am
ROA
-
TYS
1 stop4h 34m
United Airlines
Thu 2/59:30 am
TYS
-
ROA
1 stop4h 39m
United Airlines
Deal found 1/28$279
This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/306:00 am
ROA
-
TYS
1 stop3h 21m
Delta
Sun 2/15:40 am
TYS
-
ROA
1 stop4h 59m
Delta
Deal found 1/28$289
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/103:39 pm
ROA
-
TYS
1 stop5h 13m
United Airlines
Sat 2/142:21 pm
TYS
-
ROA
1 stop5h 46m
United Airlines
Deal found 1/28$319
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/32:55 pm
ROA
-
TYS
1 stop4h 32m
United Airlines
Sat 2/79:30 am
TYS
-
ROA
1 stop4h 39m
United Airlines
Deal found 1/26$329

Find flight deals from Roanoke to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$263
(United Airlines)

One-way from

$155
(Kiwi.com)
Provider with most accurate pricing for Roanoke-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Roanoke-Knoxville McGhee Tyson flights.
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From Roanoke to Knoxville McGhee Tyson
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One-way flight from Roanoke to Knoxville McGhee Tyson
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Roanoke to Knoxville that are best for you.

Fly from

Roanoke

Fly to

Knoxville

Route

Depart

Return

Price

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Wed 2/25

10:15 am-3:15 pm

1 stop5h 00m

Knoxville McGhee Tyson

Wed 3/4

9:40 am-2:12 pm

1 stop4h 32m

$263

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Tue 2/10

3:39 pm-8:52 pm

1 stop5h 13m

Knoxville McGhee Tyson

Sat 2/14

2:21 pm-8:07 pm

1 stop5h 46m

$319

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Wed 5/20

6:00 am-9:11 am

1 stop3h 11m

Knoxville McGhee Tyson

Wed 5/27

5:30 am-10:35 am

1 stop5h 05m

$352

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Thu 2/12

9:09 pm-11:38 pm

1 stop26h 29m

Knoxville McGhee Tyson

Mon 2/16

6:30 am-2:22 pm

1 stop7h 52m

$369

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Wed 5/20

10:34 am-8:45 pm

2 stops10h 11m

Knoxville McGhee Tyson

Wed 5/27

5:50 am-9:34 am

1 stop3h 44m

$457

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Fri 3/27

8:00 pm-11:50 pm

1 stop3h 50m

Knoxville McGhee Tyson

Sun 3/29

5:00 am-10:37 am

1 stop5h 37m

$585

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Thu 2/19

9:09 pm-10:05 pm

1 stop24h 56m

$155

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Thu 2/19

10:15 am-8:37 pm

2 stops10h 22m

$265

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Thu 2/19

9:09 pm-1:04 pm

3 stops39h 55m

$272

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Compare providers for flights from Roanoke to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to Knoxville in January.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
ExpediaPrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Roanoke-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Roanoke-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Roanoke-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Roanoke-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Roanoke to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated January 29, 2026.
Read reviews from past customers who have flown American Airlines from Roanoke to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,206 reviews

Comfort

7.2

Crew

8.0

Food

6.4

Overall

7.2

Boarding

7.5

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,206 reviews
American Airlines
7.2
Good
11,206 reviews

Comfort

7.2

Crew

8.0

Food

6.4

Overall

7.2

Boarding

7.5

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Roanoke to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Roanoke to Knoxville?

    Departing from Roanoke to Knoxville will take you 5h. Airlines will cover a distance of 246 mi.

  • What is the cheapest airline to fly from Roanoke to Knoxville round-trip?

    Flying on American Airlines is currently your cheapest option to Knoxville, with prices starting at $139.

  • Can I find deals for flights from Roanoke to Knoxville that include hotel bookings?

    Yes. In addition to deals on Roanoke to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to Knoxville.

  • Can I find deals for business class flights from Roanoke to Knoxville?

    Yes. Cheapflights offers flight deals from Roanoke to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Oak Ridge
Murphy

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Top airline flying from Roanoke to Knoxville

Discover the top airline that operate flights from Roanoke to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$139Average$488FlexibilityNo cancel feeOn-time71%

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