$156+ Cheap flights from Roanoke to Knoxville (ROA - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/11. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — TYS
Oct 1 — Oct 81
Round-trip
1 adult, Economy
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Find cheap flights from Roanoke to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Roanoke to Knoxville
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One-way
Cheapest flights from Roanoke to KnoxvilleExplore the most affordable flight options available from Roanoke to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 1, 2026.
Explore the most affordable flight options available from Roanoke to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 1, 2026.
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:07 pm -
1 stop3h 59m
Tue 10/66:20 am -
1 stop3h 20m
Deal found 8/31![American Airlines logo]()
$289
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:07 pm -
1 stop3h 59m
Sat 9/196:06 pm -
1 stop4h 42m
Deal found 8/31![American Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:00 pm -
1 stop3h 59m
Sat 10/319:45 am -
1 stop4h 30m
Deal found 8/27![United Airlines logo]()
$359
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/118:05 pm -
1 stop3h 54m
Tue 9/151:10 pm -
1 stop5h 56m
Deal found 8/27![United Airlines logo]()
$389
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/310:44 am -
1 stop6h 14m
Sat 9/57:00 am -
2 stops12h 07m
Deal found 8/30![United Airlines logo]()
$434
This Kiwi.com deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/1310:51 am -
1 stop24h 23m
Thu 9/175:38 pm -
1 stop14h 44m
Deal found 8/28![Allegiant Air logo]()
$445
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:15 am -
2 stops9h 20m
Tue 10/66:00 am -
2 stops13h 07m
Deal found 8/30![United Airlines logo]()
$453
This United Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/145:51 pm -
1 stop4h 58m
Fri 9/189:45 am -
1 stop24h 02m
Deal found 8/29![United Airlines logo]()
$548
Best flights from Roanoke to KnoxvilleDiscover carefully curated flight deals from Roanoke to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 1, 2026.
Discover carefully curated flight deals from Roanoke to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 1, 2026.
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:07 pm -
1 stop3h 59m
Sat 9/196:06 pm -
1 stop4h 42m
Deal found 8/31![American Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:00 pm -
1 stop3h 59m
Sat 10/319:45 am -
1 stop4h 30m
Deal found 8/29![United Airlines logo]()
$359
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:15 am -
2 stops9h 20m
Tue 10/67:25 pm -
1 stop4h 19m
Deal found 8/30![United Airlines logo]()
$364
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2910:35 am -
2 stops10h 14m
Tue 10/67:25 pm -
1 stop4h 19m
Deal found 8/31![United Airlines logo]()
$364
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/118:05 pm -
1 stop3h 54m
Tue 9/151:10 pm -
1 stop5h 56m
Deal found 8/27![United Airlines logo]()
$389
Last-minute flights from Roanoke to KnoxvilleDiscover last-minute flight deals from Roanoke to Knoxville. Data last updated September 1, 2026 and is based on user searches.
Discover last-minute flight deals from Roanoke to Knoxville. Data last updated September 1, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/312:33 pm -
1 stop6h 27m
Sat 9/53:41 pm -
1 stop6h 13m
Deal found 8/30![American Airlines logo]()
$359
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/310:44 am -
1 stop6h 14m
Sat 9/57:00 am -
2 stops12h 07m
Deal found 8/30![United Airlines logo]()
$434
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/118:05 pm -
1 stop3h 54m
Tue 9/151:10 pm -
1 stop5h 56m
Deal found 8/27![United Airlines logo]()
$389
This Kiwi.com deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/1310:51 am -
1 stop24h 23m
Thu 9/175:38 pm -
1 stop14h 44m
Deal found 8/28![Allegiant Air logo]()
$445
This United Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/145:51 pm -
1 stop4h 58m
Fri 9/189:45 am -
1 stop24h 02m
Deal found 8/29![United Airlines logo]()
$548
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:07 pm -
1 stop3h 59m
Sat 9/196:06 pm -
1 stop4h 42m
Deal found 8/31![American Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:07 pm -
1 stop3h 59m
Tue 10/66:20 am -
1 stop3h 20m
Deal found 8/31![American Airlines logo]()
$289
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2910:35 am -
2 stops10h 14m
Tue 10/67:25 pm -
1 stop4h 19m
Deal found 8/31![United Airlines logo]()
$364
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:15 am -
2 stops9h 20m
Tue 10/66:00 am -
2 stops13h 07m
Deal found 8/30![United Airlines logo]()
$453
One-way flights from Roanoke to KnoxvilleSearch for one-way flight options from Roanoke to Knoxville. Find affordable one-way fares based on user searches. Data last updated September 1, 2026.
Search for one-way flight options from Roanoke to Knoxville. Find affordable one-way fares based on user searches. Data last updated September 1, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/113:41 pm -
1 stop5h 37m
Deal found 8/31![Allegiant Air logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/291:10 pm -
1 stop7h 11m
Deal found 8/30![Allegiant Air logo]()
$190
This Kiwi.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/291:10 pm -
2 stops28h 27m
Deal found 8/30![Multiple Airlines logo]()
$230
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:40 pm -
1 stop5h 15m
Deal found 9/1![Delta logo]()
$234
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/223:00 pm -
2 stops9h 23m
Deal found 9/1![United Airlines logo]()
$298
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/113:00 pm -
3 stops26h 03m
Deal found 8/31![United Airlines logo]()
$552
Find flight deals from Roanoke to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 1, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $289 (American Airlines) |
One-way from | $156 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Roanoke to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 1, 2026.
Use the filters below to find and compare flights from Roanoke to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
RoanokeKnoxville
ROA Roanoke - TYS Knoxville McGhee Tyson
ROATYS
Roanoke
Tue 9/15
5:07 pm-9:06 pm
1 stop3h 59m
Knoxville McGhee Tyson
Sat 9/19
6:06 pm-10:48 pm
1 stop4h 42m
$319
Quickest round-trip
RoanokeKnoxville
ROA Roanoke - TYS Knoxville McGhee Tyson
ROATYS
Roanoke
Wed 10/28
8:00 pm-11:59 pm
1 stop3h 59m
Knoxville McGhee Tyson
Sat 10/31
9:45 am-2:15 pm
1 stop4h 30m
$359
RoanokeKnoxville
ROA Roanoke - TYS Knoxville McGhee Tyson
ROATYS
Roanoke
Wed 9/30
6:15 am-3:35 pm
2 stops9h 20m
Knoxville McGhee Tyson
Tue 10/6
7:25 pm-11:44 pm
1 stop4h 19m
$364
RoanokeKnoxville
ROA Roanoke - TYS Knoxville McGhee Tyson
ROATYS
Roanoke
Tue 9/29
10:35 am-8:49 pm
2 stops10h 14m
Knoxville McGhee Tyson
Tue 10/6
7:25 pm-11:44 pm
1 stop4h 19m
$364
RoanokeKnoxville
ROA Roanoke - TYS Knoxville McGhee Tyson
ROATYS
Roanoke
Fri 9/11
8:05 pm-11:59 pm
1 stop3h 54m
Knoxville McGhee Tyson
Tue 9/15
1:10 pm-7:06 pm
1 stop5h 56m
$389
Cheapest one-way
Quickest one-way
RoanokeKnoxville
ROA Roanoke - TYS Knoxville McGhee Tyson
ROATYS
Roanoke
Thu 10/29
1:10 pm-8:21 pm
1 stop7h 11m
$190
RoanokeKnoxville
ROA Roanoke - TYS Knoxville McGhee Tyson
ROATYS
Roanoke
Thu 10/29
1:10 pm-5:37 pm
2 stops28h 27m
$230
RoanokeKnoxville
ROA Roanoke - TYS Knoxville McGhee Tyson
ROATYS
Roanoke
Tue 9/22
3:00 pm-12:23 am
2 stops9h 23m
$298
RoanokeKnoxville
ROA Roanoke - TYS Knoxville McGhee Tyson
ROATYS
Roanoke
Mon 1/11
10:20 am-8:59 pm
2 stops10h 39m
$298
Sorted by cheapest first
Compare providers for flights from Roanoke to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to Knoxville in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Roanoke-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Roanoke-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Roanoke-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Roanoke-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Roanoke to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Roanoke with our price prediction graph.
ROA-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Roanoke to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
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