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$147+ Cheap flights from Roanoke to Knoxville (ROA - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/20. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — TYS
Dec 24 — Dec 311
Wed 12/24
Wed 12/31
1 adult, Economy
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Cheap flight deals from Roanoke to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 24, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$219
(Delta)

One-way from

$147
(Trip.com)
Provider with most accurate pricing for Roanoke-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Roanoke-Knoxville McGhee Tyson flights.
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From Roanoke to Knoxville McGhee Tyson
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One-way flight from Roanoke to Knoxville McGhee Tyson
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Find flight deals from Roanoke to Knoxville

Cheapest flights from Roanoke to Knoxville
Explore the most affordable flight options available from Roanoke to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 24, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/83:51 pmROA - TYS
1 stop24h 11mAllegiant Air
Fri 12/126:30 amTYS - ROA
1 stop8h 31mAllegiant Air
Deal found 11/23$270
This United Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/207:55 pmROA - TYS
1 stop4h 04mUnited Airlines
Sun 1/45:45 amTYS - ROA
1 stop4h 12mUnited Airlines
Deal found 11/23$278
This Kiwi.com deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/73:47 pmROA - TYS
2 stops24h 57mAllegiant Air
Thu 12/117:30 amTYS - ROA
1 stop7h 27mAllegiant Air
Deal found 11/21$315
This Kiwi.com deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/209:29 pmROA - TYS
2 stops43h 19mAllegiant Air
Sun 1/412:21 pmTYS - ROA
1 stop8h 45mAllegiant Air
Deal found 11/23$497
This United Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/810:20 amROA - TYS
1 stop4h 23mUnited Airlines
Fri 12/127:25 pmTYS - ROA
1 stop18h 44mUnited Airlines
Deal found 11/23$499
This United Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1810:32 amROA - TYS
1 stop13h 27mUnited Airlines
Sun 12/215:45 amTYS - ROA
1 stop4h 12mUnited Airlines
Deal found 11/24$611
This United Airlines deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/710:20 amROA - TYS
2 stops10h 44mUnited Airlines
Thu 12/117:00 amTYS - ROA
2 stops7h 09mUnited Airlines
Deal found 11/21$658

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 24, 2025.
Use the filters below to find and compare flights from Roanoke to Knoxville that are best for you.

Fly from

Roanoke

Fly to

Knoxville

Route

Depart

Return

Price

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Sat 2/21

7:59 pm-11:50 pm

1 stop3h 51m

Knoxville McGhee Tyson

Tue 2/24

5:30 am-10:41 am

1 stop5h 11m

$219

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Mon 12/8

3:51 pm-4:02 pm

1 stop24h 11m

Knoxville McGhee Tyson

Fri 12/12

6:30 am-3:01 pm

1 stop8h 31m

$270

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Sat 12/20

7:55 pm-11:59 pm

1 stop4h 04m

Knoxville McGhee Tyson

Sun 1/4

5:45 am-9:57 am

1 stop4h 12m

$278

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Sat 2/21

2:51 pm-8:27 pm

1 stop5h 36m

Knoxville McGhee Tyson

Tue 2/24

12:15 pm-8:29 pm

2 stops8h 14m

$284

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Sun 12/7

3:47 pm-4:44 pm

2 stops24h 57m

Knoxville McGhee Tyson

Thu 12/11

7:30 am-2:57 pm

1 stop7h 27m

$315

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Sat 2/21

10:15 am-9:10 pm

2 stops10h 55m

Knoxville McGhee Tyson

Tue 2/24

6:45 am-2:12 pm

2 stops7h 27m

$343

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Sat 12/20

9:29 pm-4:48 pm

2 stops43h 19m

Knoxville McGhee Tyson

Sun 1/4

12:21 pm-9:06 pm

1 stop8h 45m

$497

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Sat 12/20

9:29 pm-9:54 pm

1 stop24h 25m

$147

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Sat 12/20

5:42 pm-2:48 pm

2 stops21h 06m

$640

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/23

Compare providers for flights from Roanoke to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to Knoxville in November.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
ExpediaPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Roanoke-Knoxville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Roanoke-Knoxville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Roanoke-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Roanoke-Knoxville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Roanoke to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated November 24, 2025.
Read reviews from past customers who have flown American Airlines from Roanoke to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,046 reviews

Boarding

7.5

Entertainment

6.9

Food

6.4

Comfort

7.2

Overall

7.2

Crew

8.0

Reviews

1 / 20
8.0
Excellent

Monica,Nov 2025

JAC - DFW

At least there was an option of entertainment on this flight.
American Airlines
7.2
Good
11,046 reviews
American Airlines
7.2
Good
11,046 reviews

Boarding

7.5

Entertainment

6.9

Food

6.4

Comfort

7.2

Overall

7.2

Crew

8.0

Reviews

1 / 20
8.0
Excellent

Monica,Nov 2025

JAC - DFW

At least there was an option of entertainment on this flight.

Related info for your journey

Find useful and relevant information for your journey from Roanoke to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Roanoke to Knoxville?

    Departing from Roanoke to Knoxville will take you 3h 53m. Airlines will cover a distance of 246 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Roanoke to Knoxville that include hotel bookings?

    Yes. In addition to deals on Roanoke to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to Knoxville.

  • Can I find deals for business class flights from Roanoke to Knoxville?

    Yes. Cheapflights offers flight deals from Roanoke to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Crossville
Corbin
Bryson City
Alcoa
Oak Ridge
Murphy

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Top airline flying from Roanoke to Knoxville

Discover the top airline that operate flights from Roanoke to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 24, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$139Average$488FlexibilityNo cancel feeOn-time71%

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