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$219+ Cheap flights from Roanoke to Knoxville (ROA - TYS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/23. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — TYS
Aug 16 — Aug 231
Sat 8/16
Sat 8/23
1 adult, Economy
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Cheap flight deals from Roanoke to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 11, 2025.

Round-trip from

$219
(Delta)
From Roanoke to Knoxville McGhee Tyson
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Find flight deals from Roanoke to Knoxville

Cheapest flights from Roanoke to Knoxville
Explore the most affordable flight options available from Roanoke to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 11, 2025.

This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/236:00 amROA - TYS
1 stop4h 56mDelta
Tue 9/306:08 pmTYS - ROA
1 stop6h 17mDelta
Deal found 8/9$219
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/237:03 pmROA - TYS
1 stop4h 00mAmerican Airlines
Tue 9/308:23 amTYS - ROA
2 stops6h 13mAmerican Airlines
Deal found 8/9$225
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/118:09 pmROA - TYS
1 stop3h 58mAmerican Airlines
Mon 9/157:18 amTYS - ROA
1 stop7h 16mAmerican Airlines
Deal found 8/9$279
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/265:40 pmROA - TYS
1 stop4h 57mUnited Airlines
Sat 8/307:25 pmTYS - ROA
1 stop3h 59mUnited Airlines
Deal found 8/11$289
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/236:20 amROA - TYS
2 stops7h 05mUnited Airlines
Tue 9/307:00 amTYS - ROA
2 stops7h 04mUnited Airlines
Deal found 8/9$333
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/317:50 pmROA - TYS
1 stop4h 09mUnited Airlines
Tue 11/45:45 amTYS - ROA
1 stop4h 02mUnited Airlines
Deal found 8/10$378
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/317:55 amROA - TYS
1 stop6h 38mAmerican Airlines
Tue 11/412:46 pmTYS - ROA
2 stops7h 43mAmerican Airlines
Deal found 8/10$397
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/256:20 amROA - TYS
1 stop4h 08mUnited Airlines
Fri 8/292:00 pmTYS - ROA
1 stop20h 06mUnited Airlines
Deal found 8/10$443
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/117:35 pmROA - TYS
1 stop4h 22mUnited Airlines
Mon 9/157:00 amTYS - ROA
2 stops7h 03mUnited Airlines
Deal found 8/9$482

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 11, 2025.
Use the filters below to find and compare flights from Roanoke to Knoxville that are best for you.

Fly from

Roanoke

Fly to

Knoxville

Route

Depart

Return

Price

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Tue 9/23

6:00 am-10:56 am

1 stop4h 56m

Knoxville McGhee Tyson

Tue 9/30

6:08 pm-12:25 am

1 stop6h 17m

$219

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Tue 9/23

7:03 pm-11:03 pm

1 stop4h 00m

Knoxville McGhee Tyson

Tue 9/30

8:23 am-2:36 pm

2 stops6h 13m

$225

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Thu 9/11

8:09 pm-12:07 am

1 stop3h 58m

Knoxville McGhee Tyson

Mon 9/15

7:18 am-2:34 pm

1 stop7h 16m

$279

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Tue 8/26

5:40 pm-10:37 pm

1 stop4h 57m

Knoxville McGhee Tyson

Sat 8/30

7:25 pm-11:24 pm

1 stop3h 59m

$289

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Tue 9/23

6:20 am-1:25 pm

2 stops7h 05m

Knoxville McGhee Tyson

Tue 9/30

7:00 am-2:04 pm

2 stops7h 04m

$333

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Fri 10/31

7:50 pm-11:59 pm

1 stop4h 09m

Knoxville McGhee Tyson

Tue 11/4

5:45 am-9:47 am

1 stop4h 02m

$378

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Fri 10/31

7:55 am-2:33 pm

1 stop6h 38m

Knoxville McGhee Tyson

Tue 11/4

12:46 pm-8:29 pm

2 stops7h 43m

$397

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Mon 8/25

6:20 am-10:28 am

1 stop4h 08m

Knoxville McGhee Tyson

Fri 8/29

2:00 pm-10:06 am

1 stop20h 06m

$443

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Thu 9/11

7:35 pm-11:57 pm

1 stop4h 22m

Knoxville McGhee Tyson

Mon 9/15

7:00 am-2:03 pm

2 stops7h 03m

$482

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/9

Best time to book a flight from Roanoke to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated August 11, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Roanoke to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,978 reviews

Comfort

7.9

Overall

8.0

Boarding

8.2

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,978 reviews
Delta
8.0
Very good
7,978 reviews

Comfort

7.9

Overall

8.0

Boarding

8.2

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,922 reviews
Delta
8.0
Very good
7,978 reviews

Comfort

7.9

Overall

8.0

Boarding

8.2

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,978 reviews

Comfort

7.9

Overall

8.0

Boarding

8.2

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Roanoke to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find deals for flights from Roanoke to Knoxville that include hotel bookings?

    Yes. In addition to deals on Roanoke to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to Knoxville.

  • Can I find deals for business class flights from Roanoke to Knoxville?

    Yes. Cheapflights offers flight deals from Roanoke to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Roanoke to Knoxville (average of $294). Flying from Roanoke to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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Top airline flying from Roanoke to Knoxville

Discover the top airline that operate flights from Roanoke to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$139Average$488FlexibilityNo cancel feeOn-time71%

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