$309+ Cheap flights from Roanoke to Knoxville (ROA - TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/24. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — TYS
Oct 27 — Nov 31
Round-trip
1 adult, Economy
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Find cheap flights from Roanoke to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Roanoke to Knoxville
Cheapest
Best
Last-minute
Cheapest flights from Roanoke to KnoxvilleExplore the most affordable flight options available from Roanoke to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 27, 2026.
Explore the most affordable flight options available from Roanoke to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 27, 2026.
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2410:35 am -
1 stop4h 07m
Tue 10/279:45 am -
1 stop4h 30m
Deal found 9/22![United Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:00 pm -
1 stop3h 59m
Sat 10/311:54 pm -
1 stop7h 07m
Deal found 9/22![United Airlines logo]()
$399
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:48 pm -
1 stop5h 53m
Sun 11/13:40 pm -
1 stop21h 48m
Deal found 9/25![Allegiant Air logo]()
$460
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:49 am -
1 stop6h 25m
Wed 10/1410:42 am -
1 stop6h 22m
Deal found 9/25![United Airlines logo]()
$513
This American Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:41 am -
1 stop3h 42m
Mon 10/127:58 pm -
1 stop3h 46m
Deal found 9/26![American Airlines logo]()
$520
This American Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:07 am -
1 stop3h 25m
Mon 10/127:58 pm -
1 stop3h 46m
Deal found 9/26![American Airlines logo]()
$527
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:07 am -
1 stop3h 25m
Tue 10/138:21 am -
1 stop5h 06m
Deal found 9/25![American Airlines logo]()
$567
Best flights from Roanoke to KnoxvilleDiscover carefully curated flight deals from Roanoke to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 27, 2026.
Discover carefully curated flight deals from Roanoke to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 27, 2026.
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2410:35 am -
1 stop4h 07m
Tue 10/279:45 am -
1 stop4h 30m
Deal found 9/22![United Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:00 am -
1 stop3h 34m
Sun 11/14:11 pm -
1 stop5h 46m
Deal found 9/25![Delta logo]()
$404
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:00 pm -
1 stop3h 59m
Sat 10/311:54 pm -
1 stop7h 07m
Deal found 9/22![United Airlines logo]()
$399
Last-minute flights from Roanoke to KnoxvilleDiscover last-minute flight deals from Roanoke to Knoxville. Data last updated September 27, 2026 and is based on user searches.
Discover last-minute flight deals from Roanoke to Knoxville. Data last updated September 27, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:07 am -
1 stop3h 25m
Mon 10/127:58 pm -
1 stop3h 46m
Deal found 9/26![American Airlines logo]()
$527
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:07 am -
1 stop3h 25m
Tue 10/138:21 am -
1 stop5h 06m
Deal found 9/25![American Airlines logo]()
$567
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:49 am -
1 stop6h 25m
Wed 10/1410:42 am -
1 stop6h 22m
Deal found 9/25![United Airlines logo]()
$513
This American Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:41 am -
1 stop3h 42m
Mon 10/127:58 pm -
1 stop3h 46m
Deal found 9/26![American Airlines logo]()
$520
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2410:35 am -
1 stop4h 07m
Tue 10/279:45 am -
1 stop4h 30m
Deal found 9/22![United Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:00 pm -
1 stop3h 59m
Sat 10/311:54 pm -
1 stop7h 07m
Deal found 9/22![United Airlines logo]()
$399
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:48 pm -
1 stop5h 53m
Sun 11/13:40 pm -
1 stop21h 48m
Deal found 9/25![Allegiant Air logo]()
$460
Find flight deals from Roanoke to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 27, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $309 (United Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Roanoke to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 27, 2026.
Use the filters below to find and compare flights from Roanoke to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
RoanokeKnoxville
ROA Roanoke - TYS Knoxville McGhee Tyson
ROATYS
Roanoke
Sat 10/24
10:35 am-2:42 pm
1 stop4h 07m
Knoxville McGhee Tyson
Tue 10/27
9:45 am-2:15 pm
1 stop4h 30m
$309
RoanokeKnoxville
ROA Roanoke - TYS Knoxville McGhee Tyson
ROATYS
Roanoke
Wed 10/28
8:00 pm-11:59 pm
1 stop3h 59m
Knoxville McGhee Tyson
Sat 10/31
1:54 pm-9:01 pm
1 stop7h 07m
$399
RoanokeKnoxville
ROA Roanoke - TYS Knoxville McGhee Tyson
ROATYS
Roanoke
Fri 10/30
6:00 am-9:34 am
1 stop3h 34m
Knoxville McGhee Tyson
Sun 11/1
4:11 pm-9:57 pm
1 stop5h 46m
$404
Sorted by cheapest first
Compare providers for flights from Roanoke to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to Knoxville in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Roanoke-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Roanoke-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Roanoke-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Roanoke-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Roanoke to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Roanoke with our price prediction graph.
ROA-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Roanoke to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
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