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$221+ Cheap flights from Roanoke to Knoxville (ROA - TYS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/17. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — TYS
Dec 2 — Dec 91
Tue 12/2
Tue 12/9
1 adult, Economy
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Cheap flight deals from Roanoke to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 2, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$237
(Kiwi.com)
Provider with most accurate pricing for Roanoke-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Roanoke-Knoxville McGhee Tyson flights.
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From Roanoke to Knoxville McGhee Tyson
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Find flight deals from Roanoke to Knoxville

Cheapest flights from Roanoke to Knoxville
Explore the most affordable flight options available from Roanoke to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 2, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/178:55 pmROA - TYS
1 stop18h 19mAllegiant Air
Fri 11/218:53 amTYS - ROA
1 stop11h 40mAllegiant Air
Deal found 11/2$221
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1610:33 amROA - TYS
1 stop22h 52mAllegiant Air
Thu 11/208:00 amTYS - ROA
1 stop7h 11mAllegiant Air
Deal found 11/1$237
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/63:00 pmROA - TYS
1 stop5h 20mUnited Airlines
Thu 11/139:50 amTYS - ROA
1 stop4h 22mUnited Airlines
Deal found 11/1$279
This Mytrip deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/193:24 pmROA - TYS
1 stop6h 29mAllegiant Air
Mon 12/223:45 pmTYS - ROA
1 stop4h 56mAllegiant Air
Deal found 11/2$302
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/166:33 amROA - TYS
1 stop6h 11mAmerican Airlines
Tue 12/307:00 amTYS - ROA
1 stop3h 31mAmerican Airlines
Deal found 11/1$337
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/610:33 amROA - TYS
1 stop21h 22mMultiple Airlines
Thu 11/135:38 pmTYS - ROA
2 stops26h 47mMultiple Airlines
Deal found 11/1$347
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/166:20 amROA - TYS
1 stop4h 28mUnited Airlines
Thu 11/209:50 amTYS - ROA
1 stop4h 22mUnited Airlines
Deal found 10/31$549
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/196:15 amROA - TYS
1 stop4h 41mUnited Airlines
Mon 12/226:45 amTYS - ROA
2 stops16h 45mUnited Airlines
Deal found 11/2$591

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 2, 2025.
Use the filters below to find and compare flights from Roanoke to Knoxville that are best for you.

Fly from

Roanoke

Fly to

Knoxville

Route

Depart

Return

Price

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Mon 11/17

8:55 pm-3:14 pm

1 stop18h 19m

Knoxville McGhee Tyson

Fri 11/21

8:53 am-8:33 pm

1 stop11h 40m

$221

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Sun 11/16

10:33 am-9:25 am

1 stop22h 52m

Knoxville McGhee Tyson

Thu 11/20

8:00 am-3:11 pm

1 stop7h 11m

$237

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Sat 2/21

7:59 pm-11:50 pm

1 stop3h 51m

Knoxville McGhee Tyson

Tue 2/24

5:30 am-10:41 am

1 stop5h 11m

$273

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Sat 2/21

6:00 am-11:12 am

1 stop5h 12m

Knoxville McGhee Tyson

Tue 2/24

7:00 am-11:33 am

1 stop4h 33m

$279

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Fri 12/19

3:24 pm-9:53 pm

1 stop6h 29m

Knoxville McGhee Tyson

Mon 12/22

3:45 pm-8:41 pm

1 stop4h 56m

$302

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Tue 12/16

8:12 am-2:54 pm

2 stops6h 42m

Knoxville McGhee Tyson

Tue 12/30

7:00 am-10:31 am

1 stop3h 31m

$494

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Sun 11/16

6:20 am-1:17 pm

2 stops6h 57m

Knoxville McGhee Tyson

Thu 11/20

9:50 am-2:12 pm

1 stop4h 22m

$554

RoanokeKnoxville

ROA - TYS

ROATYS

Roanoke

Mon 11/17

10:26 am-8:33 pm

2 stops10h 07m

Knoxville McGhee Tyson

Fri 11/21

5:45 am-9:47 am

1 stop4h 02m

$554

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/2

Compare providers for flights from Roanoke to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to Knoxville in November.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
ExpediaPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Roanoke-Knoxville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Roanoke-Knoxville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Roanoke-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Roanoke-Knoxville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Roanoke to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated November 2, 2025.
Read reviews from past customers who have flown American Airlines from Roanoke to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,037 reviews

Crew

8.0

Boarding

7.5

Overall

7.2

Food

6.4

Comfort

7.2

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
11,037 reviews
American Airlines
7.2
Good
11,037 reviews

Crew

8.0

Boarding

7.5

Overall

7.2

Food

6.4

Comfort

7.2

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Roanoke to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Roanoke to Knoxville?

    Departing from Roanoke to Knoxville will take you 3h 51m. Airlines will cover a distance of 246 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Roanoke to Knoxville round-trip?

    Flying on American Airlines is currently your cheapest option to Knoxville, with prices starting at $139.

  • Can I find deals for flights from Roanoke to Knoxville that include hotel bookings?

    Yes. In addition to deals on Roanoke to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to Knoxville.

  • Can I find deals for business class flights from Roanoke to Knoxville?

    Yes. Cheapflights offers flight deals from Roanoke to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Crossville
Corbin
Bryson City
Alcoa
Oak Ridge
Murphy

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Top airline flying from Roanoke to Knoxville

Discover the top airline that operate flights from Roanoke to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$139Average$488FlexibilityNo cancel feeOn-time71%

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