$209+ Cheap flights from Knoxville to Roanoke (TYS - ROA)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/29. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — ROA
Oct 21 — Oct 281
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Roanoke with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Roanoke
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Cheapest flights from Knoxville to RoanokeExplore the most affordable flight options available from Knoxville to Roanoke. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 21, 2026.
Explore the most affordable flight options available from Knoxville to Roanoke. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 21, 2026.
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:15 am -
1 stop3h 26m
Sun 9/205:06 am -
1 stop3h 24m
Deal found 9/16![American Airlines logo]()
$379
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:45 am -
1 stop4h 03m
Fri 10/238:05 pm -
1 stop3h 54m
Deal found 9/16![United Airlines logo]()
$419
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/181:53 pm -
2 stops9h 50m
Sun 9/206:15 am -
1 stop4h 22m
Deal found 9/16![United Airlines logo]()
$454
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:23 pm -
1 stop6h 04m
Thu 10/156:00 am -
1 stop4h 54m
Deal found 9/16![Delta logo]()
$513
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:25 pm -
1 stop4h 19m
Sat 10/106:49 am -
1 stop6h 25m
Deal found 9/21![United Airlines logo]()
$578
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:45 am -
1 stop17h 59m
Sat 10/38:05 pm -
1 stop3h 54m
Deal found 9/17![United Airlines logo]()
$593
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:00 am -
2 stops17h 44m
Tue 10/68:05 pm -
1 stop3h 54m
Deal found 9/17![United Airlines logo]()
$623
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1310:42 am -
2 stops13h 02m
Thu 10/156:15 am -
1 stop4h 22m
Deal found 9/16![United Airlines logo]()
$630
Best flights from Knoxville to RoanokeDiscover carefully curated flight deals from Knoxville to Roanoke that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 21, 2026.
Discover carefully curated flight deals from Knoxville to Roanoke that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 21, 2026.
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:25 pm -
1 stop4h 19m
Sat 10/106:49 am -
1 stop6h 25m
Deal found 9/21![United Airlines logo]()
$578
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:45 am -
1 stop4h 03m
Fri 10/236:15 am -
2 stops9h 20m
Deal found 9/16![United Airlines logo]()
$589
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:45 am -
1 stop17h 59m
Sat 10/38:05 pm -
1 stop3h 54m
Deal found 9/17![United Airlines logo]()
$593
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:00 am -
2 stops17h 44m
Tue 10/68:05 pm -
1 stop3h 54m
Deal found 9/17![United Airlines logo]()
$623
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1310:42 am -
2 stops13h 02m
Thu 10/156:15 am -
1 stop4h 22m
Deal found 9/16![United Airlines logo]()
$630
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:25 pm -
1 stop4h 19m
Fri 10/98:05 pm -
1 stop18h 37m
Deal found 9/20![United Airlines logo]()
$692
Last-minute flights from Knoxville to RoanokeDiscover last-minute flight deals from Knoxville to Roanoke. Data last updated September 21, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Roanoke. Data last updated September 21, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:00 am -
2 stops7h 54m
Mon 9/286:15 am -
1 stop4h 22m
Deal found 9/16![United Airlines logo]()
$444
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:45 am -
1 stop17h 59m
Tue 10/68:05 pm -
1 stop3h 54m
Deal found 9/17![United Airlines logo]()
$593
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/210:42 am -
2 stops13h 02m
Sat 10/38:05 pm -
1 stop3h 54m
Deal found 9/17![United Airlines logo]()
$648
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:25 pm -
1 stop4h 19m
Fri 10/98:05 pm -
1 stop18h 37m
Deal found 9/20![United Airlines logo]()
$692
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:23 pm -
1 stop6h 04m
Thu 10/156:00 am -
1 stop4h 54m
Deal found 9/16![Delta logo]()
$513
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1310:42 am -
2 stops13h 02m
Thu 10/156:15 am -
1 stop4h 22m
Deal found 9/16![United Airlines logo]()
$630
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:45 am -
1 stop4h 03m
Fri 10/238:05 pm -
1 stop3h 54m
Deal found 9/16![United Airlines logo]()
$419
One-way flights from Knoxville to RoanokeSearch for one-way flight options from Knoxville to Roanoke. Find affordable one-way fares based on user searches. Data last updated September 21, 2026.
Search for one-way flight options from Knoxville to Roanoke. Find affordable one-way fares based on user searches. Data last updated September 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:33 pm -
1 stop21h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Allegiant Air logo]()
$209
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:58 pm -
1 stop3h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![American Airlines logo]()
$244
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:45 am -
2 stops7h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![United Airlines logo]()
$284
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:40 pm -
3 stops20h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![United Airlines logo]()
$435
Find flight deals from Knoxville to Roanoke
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Roanoke (ROA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $419 (United Airlines) |
One-way from | $209 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Roanoke that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 21, 2026.
Use the filters below to find and compare flights from Knoxville to Roanoke that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleRoanoke
TYS Knoxville McGhee Tyson - ROA Roanoke
TYSROA
Knoxville McGhee Tyson
Thu 10/29
5:33 pm-2:58 pm
1 stop21h 25m
Roanoke
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$209
Quickest round-trip
KnoxvilleRoanoke
TYS Knoxville McGhee Tyson - ROA Roanoke
TYSROA
Knoxville McGhee Tyson
Thu 10/29
6:45 am-2:15 pm
2 stops7h 30m
Roanoke
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$284
KnoxvilleRoanoke
TYS Knoxville McGhee Tyson - ROA Roanoke
TYSROA
Knoxville McGhee Tyson
Fri 10/30
5:40 pm-2:15 pm
3 stops20h 35m
Roanoke
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$435
KnoxvilleRoanoke
TYS Knoxville McGhee Tyson - ROA Roanoke
TYSROA
Knoxville McGhee Tyson
Tue 10/6
7:25 pm-11:44 pm
1 stop4h 19m
Roanoke
Sat 10/10
6:49 am-1:14 pm
1 stop6h 25m
$578
KnoxvilleRoanoke
TYS Knoxville McGhee Tyson - ROA Roanoke
TYSROA
Knoxville McGhee Tyson
Fri 10/16
5:45 am-9:48 am
1 stop4h 03m
Roanoke
Fri 10/23
6:15 am-3:35 pm
2 stops9h 20m
$589
KnoxvilleRoanoke
TYS Knoxville McGhee Tyson - ROA Roanoke
TYSROA
Knoxville McGhee Tyson
Fri 10/2
5:45 am-11:44 pm
1 stop17h 59m
Roanoke
Sat 10/3
8:05 pm-11:59 pm
1 stop3h 54m
$593
KnoxvilleRoanoke
TYS Knoxville McGhee Tyson - ROA Roanoke
TYSROA
Knoxville McGhee Tyson
Fri 10/2
6:00 am-11:44 pm
2 stops17h 44m
Roanoke
Tue 10/6
8:05 pm-11:59 pm
1 stop3h 54m
$623
KnoxvilleRoanoke
TYS Knoxville McGhee Tyson - ROA Roanoke
TYSROA
Knoxville McGhee Tyson
Tue 10/13
10:42 am-11:44 pm
2 stops13h 02m
Roanoke
Thu 10/15
6:15 am-10:37 am
1 stop4h 22m
$630
KnoxvilleRoanoke
TYS Knoxville McGhee Tyson - ROA Roanoke
TYSROA
Knoxville McGhee Tyson
Mon 10/5
7:25 pm-11:44 pm
1 stop4h 19m
Roanoke
Fri 10/9
8:05 pm-2:42 pm
1 stop18h 37m
$692
Sorted by cheapest first
Compare providers for flights from Knoxville to Roanoke
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Roanoke in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-Roanoke flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Roanoke flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Roanoke flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Roanoke flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Roanoke flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Roanoke
Have a flexible travel schedule? Discover the best time to fly to Roanoke from Knoxville with our price prediction graph.
TYS-ROA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Roanoke. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Roanoke?
Book flights to Roanoke if you plan to visit one of these locationsSalem
Blacksburg
Christiansburg
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