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Knoxville

$96+ Cheap flights from Ohio to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/16. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — TYS
Aug 27 — Sep 31
Thu 8/27
Thu 9/3
1 adult, Economy
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Cheap flight deals from Ohio to Knoxville

Cheapest flights from Ohio to Knoxville
Explore the most affordable flight options available from Ohio to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2026.

This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/28:15 am
CAK
-
TYS
1 stop25h 49m
Multiple Airlines
Sun 9/612:52 pm
TYS
-
CAK
1 stop11h 05m
Multiple Airlines
Deal found 7/24$186
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/24:38 pm
CLE
-
TYS
1 stop17h 26m
Multiple Airlines
Wed 9/1610:54 am
TYS
-
CLE
1 stop9h 12m
Multiple Airlines
Deal found 7/26$194
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/28:15 am
CAK
-
TYS
1 stop25h 49m
Multiple Airlines
Wed 9/910:54 am
TYS
-
CAK
2 stops24h 33m
Multiple Airlines
Deal found 7/24$196
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/304:35 pm
CAK
-
TYS
1 stop25h 51m
Multiple Airlines
Sun 9/612:52 pm
TYS
-
CAK
1 stop11h 05m
Multiple Airlines
Deal found 7/24$203
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/28:15 am
CAK
-
TYS
1 stop25h 49m
Multiple Airlines
Thu 9/105:21 pm
TYS
-
CAK
2 stops29h 05m
Multiple Airlines
Deal found 7/24$205
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/319:11 pm
CAK
-
TYS
1 stop12h 29m
Multiple Airlines
Sun 9/612:52 pm
TYS
-
CAK
1 stop11h 05m
Multiple Airlines
Deal found 7/24$206
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/28:15 am
CAK
-
TYS
1 stop25h 49m
Multiple Airlines
Sat 9/126:55 pm
TYS
-
CAK
2 stops16h 32m
Multiple Airlines
Deal found 7/24$214
This Kiwi.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/34:36 pm
CAK
-
TYS
1 stop5h 24m
Allegiant Air
Thu 8/67:45 am
TYS
-
CAK
1 stop11h 30m
Allegiant Air
Deal found 7/25$215
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/319:11 pm
CAK
-
TYS
1 stop12h 29m
Multiple Airlines
Wed 9/910:54 am
TYS
-
CAK
2 stops24h 33m
Multiple Airlines
Deal found 7/24$216
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/304:35 pm
CAK
-
TYS
1 stop20h 00m
Multiple Airlines
Wed 9/910:54 am
TYS
-
CAK
2 stops24h 33m
Multiple Airlines
Deal found 7/24$217
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/110:18 am
DTW
-
TYS
1 stop23h 46m
Multiple Airlines
Thu 9/312:52 pm
TYS
-
DTW
2 stops12h 12m
Multiple Airlines
Deal found 7/27$217
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/249:01 am
CLE
-
TYS
1 stop10h 04m
Multiple Airlines
Mon 8/312:49 pm
TYS
-
CLE
1 stop17h 07m
Multiple Airlines
Deal found 7/24$223

Find flight deals from Ohio to Knoxville

Keep the following information in mind while searching for Ohio to Knoxville flight deals. Data was last updated July 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$186
(Kiwi.com)

One-way from

$96
(Kiwi.com)

Popular in

October

Cheapest in

September

Average price

$399
Provider with most accurate pricing for Cleveland Hopkins Intl-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Knoxville McGhee Tyson flights.
Search Deals
From Ohio to Knoxville McGhee Tyson
Search Deals
One-way flight from Ohio to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 21% potential increase in price ($104 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($30 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Ohio to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2026.
Use the filters below to find and compare flights from Ohio to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ClevelandKnoxville

CLE - TYS

CLETYS

Cleveland Hopkins Intl

Thu 8/27

5:26 am-9:36 am

1 stop4h 10m

Knoxville McGhee Tyson

Sat 8/29

7:15 am-1:40 pm

1 stop6h 25m

$233

ClevelandKnoxville

CLE - TYS

CLETYS

Cleveland Hopkins Intl

Sat 9/5

2:15 pm-8:53 pm

1 stop6h 38m

Knoxville McGhee Tyson

Mon 9/7

7:00 am-11:16 am

1 stop4h 16m

$233

ClevelandKnoxville

CLE - TYS

CLETYS

Cleveland Hopkins Intl

Sat 9/12

12:16 pm-4:58 pm

1 stop4h 42m

Knoxville McGhee Tyson

Wed 9/16

6:00 pm-10:39 pm

1 stop4h 39m

$233

ClevelandKnoxville

CLE - TYS

CLETYS

Cleveland Hopkins Intl

Mon 8/31

5:40 am-12:20 pm

2 stops6h 40m

Knoxville McGhee Tyson

Tue 9/1

7:00 am-2:45 pm

2 stops7h 45m

$243
Quickest round-trip

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Sat 9/12

6:00 pm-7:38 pm

Nonstop1h 38m

Knoxville McGhee Tyson

Mon 9/14

5:28 pm-7:12 pm

Nonstop1h 44m

$259

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Sat 8/22

1:08 pm-7:00 pm

1 stop5h 52m

Knoxville McGhee Tyson

Mon 8/24

6:52 pm-11:33 pm

1 stop4h 41m

$265

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Thu 8/20

12:10 pm-5:42 pm

1 stop5h 32m

Knoxville McGhee Tyson

Thu 8/27

11:38 am-6:13 pm

1 stop6h 35m

$265

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Thu 8/20

5:20 am-9:57 am

1 stop4h 37m

Knoxville McGhee Tyson

Thu 8/27

6:02 pm-11:59 pm

1 stop5h 57m

$265

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Mon 10/5

7:19 pm-11:55 pm

1 stop4h 36m

Knoxville McGhee Tyson

Thu 10/8

5:45 am-12:02 pm

1 stop6h 17m

$265

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Sat 10/10

5:11 am-9:45 am

1 stop4h 34m

Knoxville McGhee Tyson

Sat 10/17

7:25 pm-11:30 pm

1 stop4h 05m

$265

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/23

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Ohio to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to Knoxville

What is the cheapest month to book a flight from Ohio to Knoxville?

Currently, February is the cheapest month in which you can book a flight from Ohio to Knoxville (average of $267). Flying from Ohio to Knoxville in November is currently the most expensive (average of $456). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Ohio to Knoxville?

Airfare is below average for this route at the moment.
Ohio to Knoxville flights typically cost between $237 and $316 in September.
The cheapest round-trip price found within the last 5 days was $194 on Multiple Airlines (Sep 2-Sep 16).

Related info for your journey

Find useful and relevant information for your journey from Ohio to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Ohio?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to Knoxville from Ohio.

  • How long is the flight from Ohio to Knoxville?

    Departing from Ohio to Knoxville will take you 4h 10m. The distance from Ohio to Knoxville is about 404 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Ohio to Knoxville one-way?

    The cheapest airlines for a one-way flight from Ohio to Knoxville are United Airlines ($121), Delta ($140), and American Airlines ($168).

  • What are the most popular routes from Ohio to Knoxville?

    Most travelers choose Detroit Metropolitan Wayne County - Knoxville McGhee Tyson, Pittsburgh - Knoxville McGhee Tyson or Columbus - Knoxville McGhee Tyson when deciding on the best route from Ohio to Knoxville.

  • Can I find deals for flights from Ohio to Knoxville that include hotel bookings?

    Yes. In addition to deals on Ohio to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to Knoxville.

  • Can I find deals for business class flights from Ohio to Knoxville?

    Yes. Cheapflights offers flight deals from Ohio to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ohio to Knoxville?

    Currently, February is the cheapest month in which you can book a flight from Ohio to Knoxville (average of $267). Flying from Ohio to Knoxville in November is currently the most expensive (average of $456). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa

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Top 4 airlines flying from Ohio to Knoxville

Discover the top 4 airlines that operate flights from Ohio to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$228Average$364FlexibilityNo cancel feeOn-time71%
DeltaCheapest$232Average$416FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$235Average$412FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$263Average$316FlexibilityNo cancel feeOn-time63%

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