$100+ Cheap flights from Ohio to Knoxville (TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/30. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — TYS
Oct 10 — Oct 171
Round-trip
1 adult, Economy
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Find cheap flights from Ohio to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Ohio to Knoxville
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Cheapest flights from Ohio to KnoxvilleExplore the most affordable flight options available from Ohio to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
Explore the most affordable flight options available from Ohio to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/259:59 pm -
1 stop23h 45m
Fri 10/309:41 pm -
2 stops15h 53m
Deal found 9/5![Multiple Airlines logo]()
$218
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/293:25 pm -
2 stops23h 17m
Thu 10/11:37 pm -
1 stop6h 25m
Deal found 9/8![Multiple Airlines logo]()
$223
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/134:29 pm -
1 stop17h 36m
Tue 10/207:04 pm -
1 stop28h 25m
Deal found 9/10![Multiple Airlines logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/169:59 pm -
1 stop23h 44m
Wed 10/212:43 pm -
1 stop18h 14m
Deal found 9/8![Multiple Airlines logo]()
$248
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1212:07 pm -
1 stop9h 58m
Sun 11/156:33 pm -
1 stop20h 08m
Deal found 9/9![Multiple Airlines logo]()
$253
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/104:29 pm -
1 stop17h 36m
Thu 11/128:55 am -
1 stop14h 42m
Deal found 9/8![Multiple Airlines logo]()
$253
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:50 pm -
1 stop4h 30m
Tue 10/61:50 pm -
1 stop9h 51m
Deal found 9/8![Multiple Airlines logo]()
$253
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2512:00 pm -
1 stop5h 33m
Sun 11/12:01 pm -
1 stop7h 24m
Deal found 9/10![Multiple Airlines logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/64:23 pm -
1 stop17h 42m
Fri 10/910:07 pm -
1 stop13h 32m
Deal found 9/7![Multiple Airlines logo]()
$258
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/104:29 pm -
1 stop17h 36m
Fri 11/132:38 pm -
1 stop8h 59m
Deal found 9/8![Multiple Airlines logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/188:19 pm -
1 stop14h 55m
Wed 10/212:43 pm -
1 stop9h 00m
Deal found 9/9![Multiple Airlines logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:20 am -
1 stop10h 23m
Thu 10/11:37 pm -
2 stops22h 27m
Deal found 9/9![Multiple Airlines logo]()
$267
Best flights from Ohio to KnoxvilleDiscover carefully curated flight deals from Ohio to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
Discover carefully curated flight deals from Ohio to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2512:00 pm -
1 stop5h 33m
Sun 11/12:01 pm -
1 stop7h 24m
Deal found 9/10![Multiple Airlines logo]()
$254
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:26 am -
1 stop4h 11m
Wed 10/281:56 pm -
1 stop6h 53m
Deal found 9/8![United Airlines logo]()
$273
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/66:25 am -
1 stop5h 45m
Sat 1/96:55 am -
2 stops6h 25m
Deal found 9/9![Southwest logo]()
$278
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:00 am -
1 stop3h 34m
Fri 10/306:23 pm -
1 stop6h 21m
Deal found 9/8![Delta logo]()
$287
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:13 am -
1 stop4h 52m
Mon 11/211:33 am -
1 stop4h 44m
Deal found 9/5![American Airlines logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/209:13 pm -
1 stop15h 49m
Thu 9/241:31 pm -
1 stop6h 52m
Deal found 9/5![Allegiant Air logo]()
$300
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/49:59 pm -
1 stop23h 36m
Tue 11/106:08 pm -
1 stop24h 54m
Deal found 9/9![Multiple Airlines logo]()
$269
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/52:40 pm -
2 stops8h 05m
Thu 10/87:25 pm -
1 stop3h 35m
Deal found 9/7![Southwest logo]()
$278
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:00 am -
1 stop3h 34m
Mon 10/127:45 pm -
1 stop5h 12m
Deal found 9/8![Delta logo]()
$289
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:26 am -
1 stop4h 39m
Sat 10/106:06 pm -
1 stop4h 14m
Deal found 9/8![American Airlines logo]()
$299
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/33:50 pm -
1 stop4h 55m
Tue 12/87:05 am -
2 stops9h 05m
Deal found 9/9![Southwest logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/229:59 pm -
1 stop14h 15m
Mon 10/262:12 pm -
2 stops30h 42m
Deal found 9/5![Multiple Airlines logo]()
$284
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:15 am -
1 stop4h 38m
Tue 11/36:45 am -
1 stop6h 25m
Deal found 9/5![United Airlines logo]()
$325
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/123:00 pm -
1 stop5h 08m
Fri 10/237:45 pm -
1 stop4h 30m
Deal found 9/8![Delta logo]()
$301
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/199:06 pm -
1 stop21h 46m
Fri 10/238:40 pm -
1 stop21h 34m
Deal found 9/7![Allegiant Air logo]()
$350
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:11 pm -
1 stop5h 31m
Sat 10/106:56 am -
1 stop4h 13m
Deal found 9/6![American Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/284:25 pm -
1 stop4h 24m
Thu 10/15:45 am -
1 stop3h 59m
Deal found 9/6![United Airlines logo]()
$325
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/125:40 pm -
1 stop4h 09m
Thu 10/152:37 pm -
2 stops21h 01m
Deal found 9/9![Multiple Airlines logo]()
$297
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/34:00 pm -
1 stop4h 45m
Sat 11/72:50 pm -
1 stop3h 30m
Deal found 9/7![Southwest logo]()
$310
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:00 am -
1 stop5h 40m
Sun 10/115:40 am -
1 stop3h 14m
Deal found 9/9![Delta logo]()
$310
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/302:45 pm -
1 stop4h 32m
Wed 2/35:20 pm -
1 stop6h 22m
Deal found 9/7![United Airlines logo]()
$343
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/263:50 pm -
2 stops6h 55m
Fri 10/307:25 pm -
1 stop3h 25m
Deal found 9/8![Southwest logo]()
$318
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:15 pm -
1 stop4h 29m
Mon 10/127:45 pm -
1 stop5h 01m
Deal found 9/7![Delta logo]()
$321
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:15 am -
1 stop4h 38m
Mon 11/235:40 pm -
1 stop6h 04m
Deal found 9/6![United Airlines logo]()
$346
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:45 am -
2 stops10h 55m
Wed 10/148:20 am -
1 stop4h 10m
Deal found 9/9![Southwest logo]()
$321
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:00 am -
1 stop3h 34m
Sun 10/119:12 am -
1 stop4h 47m
Deal found 9/9![Delta logo]()
$330
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/53:50 pm -
2 stops6h 55m
Wed 10/78:20 am -
1 stop4h 00m
Deal found 9/6![Southwest logo]()
$330
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:00 am -
1 stop3h 32m
Sun 10/117:58 pm -
1 stop4h 06m
Deal found 9/6![American Airlines logo]()
$456
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:30 am -
2 stops9h 38m
Mon 10/57:25 pm -
1 stop4h 05m
Deal found 9/5![United Airlines logo]()
$396
This Southwest deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/291:20 pm -
2 stops8h 15m
Tue 11/37:05 am -
1 stop5h 25m
Deal found 9/5![Southwest logo]()
$330
Last-minute flights from Ohio to KnoxvilleDiscover last-minute flight deals from Ohio to Knoxville. Data last updated September 10, 2026 and is based on user searches.
Discover last-minute flight deals from Ohio to Knoxville. Data last updated September 10, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:20 am -
1 stop10h 23m
Thu 10/11:37 pm -
2 stops22h 27m
Deal found 9/9![Multiple Airlines logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/293:25 pm -
2 stops23h 17m
Thu 10/11:37 pm -
1 stop6h 25m
Deal found 9/8![Multiple Airlines logo]()
$223
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:33 pm -
1 stop4h 17m
Mon 10/56:05 pm -
1 stop5h 30m
Deal found 9/9![American Airlines logo]()
$273
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:50 pm -
1 stop4h 30m
Tue 10/61:50 pm -
1 stop9h 51m
Deal found 9/8![Multiple Airlines logo]()
$253
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/54:23 pm -
1 stop24h 51m
Mon 10/129:33 pm -
1 stop25h 56m
Deal found 9/6![Multiple Airlines logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/64:23 pm -
1 stop17h 42m
Fri 10/910:07 pm -
1 stop13h 32m
Deal found 9/7![Multiple Airlines logo]()
$258
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/134:29 pm -
1 stop17h 36m
Tue 10/207:04 pm -
1 stop28h 25m
Deal found 9/10![Multiple Airlines logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/134:29 pm -
1 stop17h 36m
Wed 10/284:14 pm -
1 stop7h 23m
Deal found 9/10![Multiple Airlines logo]()
$268
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/169:59 pm -
1 stop23h 44m
Wed 10/212:43 pm -
1 stop18h 14m
Deal found 9/8![Multiple Airlines logo]()
$248
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/188:19 pm -
1 stop14h 55m
Wed 10/212:43 pm -
1 stop9h 00m
Deal found 9/9![Multiple Airlines logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/259:59 pm -
1 stop23h 45m
Fri 10/309:41 pm -
2 stops15h 53m
Deal found 9/5![Multiple Airlines logo]()
$218
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2512:00 pm -
1 stop5h 33m
Sun 11/12:01 pm -
1 stop7h 24m
Deal found 9/10![Multiple Airlines logo]()
$254
One-way flights from Ohio to KnoxvilleSearch for one-way flight options from Ohio to Knoxville. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
Search for one-way flight options from Ohio to Knoxville. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:00 am -
1 stop8h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Multiple Airlines logo]()
$100
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/293:45 pm -
2 stops22h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Multiple Airlines logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/189:59 pm -
1 stop13h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/29:10 pm -
1 stop23h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/104:29 pm -
1 stop17h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/34:29 pm -
1 stop17h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/113:02 pm -
2 stops31h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Multiple Airlines logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/257:44 pm -
2 stops26h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/210:25 pm -
1 stop22h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Allegiant Air logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/44:23 pm -
1 stop18h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Multiple Airlines logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/79:10 pm -
1 stop15h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Multiple Airlines logo]()
$130
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/69:10 pm -
1 stop11h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Multiple Airlines logo]()
$131
Find flight deals from Ohio to Knoxville
Keep the following information in mind while searching for Ohio to Knoxville flight deals. Data was last updated September 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $218 (Kiwi.com) |
One-way from | $100 (Kiwi.com) |
Popular in | November |
Cheapest in | February |
Average price | $333 |
Cheapflights Fare Finder
Customize your flight search to find flights from Ohio to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
Use the filters below to find and compare flights from Ohio to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ClevelandKnoxville
CLE Cleveland Hopkins Intl - TYS Knoxville McGhee Tyson
CLETYS
Cleveland Hopkins Intl
Wed 9/30
3:45 pm-11:39 pm
2 stops31h 54m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$106
PittsburghKnoxville
PIT Pittsburgh - TYS Knoxville McGhee Tyson
PITTYS
Pittsburgh
Mon 10/5
4:32 pm-10:20 pm
1 stop5h 48m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$129
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Tue 10/6
7:00 am-10:54 am
1 stop3h 54m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$137
Quickest round-trip
PittsburghKnoxville
PIT Pittsburgh - TYS Knoxville McGhee Tyson
PITTYS
Pittsburgh
Sat 11/7
2:20 pm-5:40 pm
1 stop3h 20m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$137
CincinnatiKnoxville
CVG Cincinnati Cinci./N. Kentucky - TYS Knoxville McGhee Tyson
CVGTYS
Cincinnati Cinci./N. Kentucky
Thu 10/15
5:30 am-9:45 am
1 stop4h 15m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$137
ClevelandKnoxville
CLE Cleveland Hopkins Intl - TYS Knoxville McGhee Tyson
CLETYS
Cleveland Hopkins Intl
Tue 10/13
6:00 am-10:54 am
1 stop4h 54m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$137
PittsburghKnoxville
PIT Pittsburgh - TYS Knoxville McGhee Tyson
PITTYS
Pittsburgh
Sun 10/11
6:45 am-11:30 pm
1 stop16h 45m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$140
AkronKnoxville
CAK Akron/Canton - TYS Knoxville McGhee Tyson
CAKTYS
Akron/Canton
Sat 10/3
2:04 pm-1:44 pm
1 stop23h 40m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$140
PittsburghKnoxville
PIT Pittsburgh - TYS Knoxville McGhee Tyson
PITTYS
Pittsburgh
Mon 10/5
4:16 pm-11:59 pm
2 stops7h 43m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$142
ClevelandKnoxville
CLE Cleveland Hopkins Intl - TYS Knoxville McGhee Tyson
CLETYS
Cleveland Hopkins Intl
Thu 10/8
6:00 am-9:34 am
1 stop3h 34m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$145
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Ohio to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Ohio with our price prediction graph.
CLE-TYS
DTW-TYS
CMH-TYS
PIT-TYS
CVG-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Ohio to Knoxville
USOH-TYS
CLE-TYS
DTW-TYS
CMH-TYS
PIT-TYS
What is the cheapest month to book a flight from Ohio to Knoxville?
Currently, February is the cheapest month in which you can book a flight from Ohio to Knoxville (average of $267). Flying from Ohio to Knoxville in January is currently the most expensive (average of $547). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Ohio to Knoxville?
Airfare is below average for this route at the moment.
Ohio to Knoxville flights typically cost between $302 and $422 in October.The cheapest round-trip price found within the last 5 days was $218 on Multiple Airlines (Oct 25-Oct 30).
Related info for your journey
Find useful and relevant information for your journey from Ohio to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Ohio to Knoxville
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Complete your trip
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Search flights from Ohio to Knoxville by cabin class
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Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 10, 2026.
Ohio and Knoxville flights
Browse other Ohio and Knoxville flight options. Last updated on September 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Ohio to Knoxville flights
Consider these flights traveling from Ohio to Knoxville.
Top 4 airlines flying from Ohio to Knoxville
Discover the top 4 airlines that operate flights from Ohio to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$228 | Average$373 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$235 | Average$381 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$263 | Average$316 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$266 | Average$442 | FlexibilityNo cancel fee | On-timeN/A |