$104+ Cheap flights from Ohio to Knoxville (TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/12. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — TYS
Nov 24 — Dec 11
Round-trip
1 adult, Economy
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Find cheap flights from Ohio to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Ohio to KnoxvilleExplore the most affordable flight options available from Ohio to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
Explore the most affordable flight options available from Ohio to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:15 am -
1 stop4h 30m
Wed 11/114:59 pm -
1 stop6h 54m
Deal found 10/22![American Airlines logo]()
$239
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/145:09 pm -
1 stop5h 03m
Tue 11/176:10 pm -
1 stop6h 27m
Deal found 10/21![Delta logo]()
$239
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/51:00 pm -
2 stops6h 45m
Sat 12/122:50 pm -
1 stop3h 30m
Deal found 10/20![Southwest logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/179:18 pm -
1 stop14h 48m
Tue 11/249:51 pm -
1 stop10h 50m
Deal found 10/20![Multiple Airlines logo]()
$253
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/141:00 pm -
1 stop4h 45m
Tue 11/171:00 pm -
2 stops8h 25m
Deal found 10/21![Southwest logo]()
$257
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:05 am -
2 stops12h 45m
Fri 11/1312:50 pm -
1 stop5h 15m
Deal found 10/22![Southwest logo]()
$259
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/81:14 pm -
1 stop4h 29m
Thu 11/127:45 am -
2 stops30h 09m
Deal found 10/23![Multiple Airlines logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/269:10 pm -
1 stop20h 04m
Tue 11/32:52 pm -
1 stop18h 14m
Deal found 10/24![Multiple Airlines logo]()
$270
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/112:55 pm -
1 stop5h 48m
Fri 11/134:59 pm -
1 stop6h 54m
Deal found 10/22![American Airlines logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/279:18 pm -
2 stops38h 11m
Wed 11/49:00 am -
1 stop24h 06m
Deal found 10/24![Multiple Airlines logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/269:10 pm -
1 stop20h 04m
Wed 11/49:00 am -
1 stop24h 06m
Deal found 10/24![Multiple Airlines logo]()
$283
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:05 am -
1 stop4h 23m
Fri 11/207:10 am -
1 stop4h 21m
Deal found 10/23![Delta logo]()
$287
Best flights from Ohio to KnoxvilleDiscover carefully curated flight deals from Ohio to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
Discover carefully curated flight deals from Ohio to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/86:30 am -
1 stop3h 57m
Tue 12/152:36 pm -
1 stop3h 33m
Deal found 10/20![Delta logo]()
$239
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1012:38 pm -
1 stop6h 08m
Wed 11/116:48 am -
1 stop5h 23m
Deal found 10/19![American Airlines logo]()
$239
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/108:45 am -
2 stops11h 05m
Wed 11/115:15 pm -
1 stop4h 00m
Deal found 10/19![Southwest logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/81:14 pm -
1 stop4h 29m
Thu 11/127:45 am -
2 stops30h 09m
Deal found 10/23![Multiple Airlines logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/81:14 pm -
1 stop4h 29m
Thu 11/122:09 pm -
1 stop19h 12m
Deal found 10/23![Allegiant Air logo]()
$317
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/73:58 pm -
1 stop4h 56m
Wed 11/116:45 am -
1 stop6h 27m
Deal found 10/24![United Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/145:09 pm -
1 stop5h 03m
Tue 11/176:10 pm -
1 stop6h 27m
Deal found 10/21![Delta logo]()
$239
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/51:00 pm -
2 stops6h 45m
Sat 12/122:50 pm -
1 stop3h 30m
Deal found 10/20![Southwest logo]()
$244
This Southwest deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/195:50 am -
2 stops6h 25m
Sat 1/232:25 pm -
2 stops8h 30m
Deal found 10/23![Southwest logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1612:40 pm -
2 stops29h 12m
Wed 1/64:09 pm -
1 stop16h 20m
Deal found 10/20![Multiple Airlines logo]()
$299
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:00 am -
1 stop4h 01m
Sun 12/135:40 am -
1 stop4h 41m
Deal found 10/20![Delta logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:15 am -
1 stop15h 17m
Tue 11/108:30 am -
1 stop28h 34m
Deal found 10/22![Allegiant Air logo]()
$321
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:05 am -
2 stops12h 45m
Fri 11/1312:50 pm -
2 stops11h 00m
Deal found 10/22![Southwest logo]()
$270
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:36 pm -
1 stop5h 11m
Sun 11/156:48 am -
1 stop4h 06m
Deal found 10/19![American Airlines logo]()
$329
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/312:43 pm -
2 stops21h 22m
Wed 11/48:01 pm -
1 stop13h 16m
Deal found 10/20![Multiple Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:05 am -
1 stop4h 23m
Fri 11/207:10 am -
1 stop4h 21m
Deal found 10/23![Delta logo]()
$287
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:30 am -
1 stop4h 23m
Mon 11/95:45 am -
1 stop4h 19m
Deal found 10/21![United Airlines logo]()
$364
This Southwest deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/31:55 pm -
2 stops5h 55m
Sat 12/52:50 pm -
2 stops6h 50m
Deal found 10/24![Southwest logo]()
$297
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/117:05 pm -
1 stop4h 52m
Mon 12/146:17 pm -
1 stop6h 16m
Deal found 10/20![Delta logo]()
$303
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3012:32 pm -
1 stop5h 01m
Sat 10/3111:35 am -
1 stop7h 12m
Deal found 10/23![American Airlines logo]()
$379
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/51:29 pm -
1 stop9h 08m
Mon 11/99:10 am -
2 stops33h 46m
Deal found 10/21![Multiple Airlines logo]()
$361
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/101:10 pm -
1 stop4h 20m
Mon 12/145:10 pm -
1 stop3h 53m
Deal found 10/20![Delta logo]()
$303
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/710:20 am -
1 stop6h 34m
Mon 1/115:55 pm -
1 stop6h 11m
Deal found 10/24![United Airlines logo]()
$409
This Southwest deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:25 am -
2 stops8h 25m
Fri 11/207:25 pm -
1 stop3h 10m
Deal found 10/23![Southwest logo]()
$317
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/101:10 pm -
1 stop4h 20m
Tue 12/1512:32 pm -
1 stop3h 58m
Deal found 10/20![Delta logo]()
$303
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/125:00 am -
1 stop4h 52m
Tue 2/166:25 am -
1 stop6h 56m
Deal found 10/24![United Airlines logo]()
$409
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/412:36 pm -
2 stops23h 02m
Sun 11/82:09 pm -
1 stop8h 53m
Deal found 10/20![Multiple Airlines logo]()
$374
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/126:20 am -
1 stop4h 36m
Tue 2/166:35 am -
1 stop5h 01m
Deal found 10/22![American Airlines logo]()
$434
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/107:05 pm -
1 stop4h 52m
Wed 12/165:10 pm -
1 stop3h 53m
Deal found 10/20![Delta logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/138:55 pm -
1 stop13h 10m
Sun 11/156:33 pm -
2 stops17h 15m
Deal found 10/19![Multiple Airlines logo]()
$402
Last-minute flights from Ohio to KnoxvilleDiscover last-minute flight deals from Ohio to Knoxville. Data last updated October 25, 2026 and is based on user searches.
Discover last-minute flight deals from Ohio to Knoxville. Data last updated October 25, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/269:10 pm -
1 stop20h 04m
Tue 11/32:52 pm -
1 stop18h 14m
Deal found 10/24![Multiple Airlines logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/269:10 pm -
1 stop20h 04m
Wed 11/49:00 am -
1 stop24h 06m
Deal found 10/24![Multiple Airlines logo]()
$283
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/279:18 pm -
2 stops38h 11m
Wed 11/49:00 am -
1 stop24h 06m
Deal found 10/24![Multiple Airlines logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/81:14 pm -
1 stop4h 29m
Thu 11/127:45 am -
2 stops30h 09m
Deal found 10/23![Multiple Airlines logo]()
$263
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:15 am -
1 stop4h 30m
Wed 11/114:59 pm -
1 stop6h 54m
Deal found 10/22![American Airlines logo]()
$239
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:05 am -
2 stops12h 45m
Fri 11/1312:50 pm -
1 stop5h 15m
Deal found 10/22![Southwest logo]()
$259
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/112:55 pm -
1 stop5h 48m
Fri 11/134:59 pm -
1 stop6h 54m
Deal found 10/22![American Airlines logo]()
$271
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am -
1 stop3h 55m
Sun 11/155:10 pm -
1 stop6h 43m
Deal found 10/21![Delta logo]()
$287
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/145:09 pm -
1 stop5h 03m
Tue 11/176:10 pm -
1 stop6h 27m
Deal found 10/21![Delta logo]()
$239
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/141:00 pm -
1 stop4h 45m
Tue 11/171:00 pm -
2 stops8h 25m
Deal found 10/21![Southwest logo]()
$257
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/179:18 pm -
1 stop14h 48m
Tue 11/249:51 pm -
1 stop10h 50m
Deal found 10/20![Multiple Airlines logo]()
$253
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:05 am -
1 stop4h 23m
Fri 11/207:10 am -
1 stop4h 21m
Deal found 10/23![Delta logo]()
$287
One-way flights from Ohio to KnoxvilleSearch for one-way flight options from Ohio to Knoxville. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
Search for one-way flight options from Ohio to Knoxville. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/121:29 pm -
1 stop9h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Multiple Airlines logo]()
$104
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1011:22 am -
1 stop6h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Delta logo]()
$120
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:51 pm -
1 stop3h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![American Airlines logo]()
$120
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:25 am -
2 stops8h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Southwest logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/319:59 pm -
2 stops40h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/28:18 pm -
1 stop20h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Multiple Airlines logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:44 pm -
2 stops39h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Multiple Airlines logo]()
$139
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:10 am -
1 stop7h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![Allegiant Air logo]()
$148
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/208:05 am -
1 stop6h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Delta logo]()
$152
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/278:05 am -
1 stop5h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Delta logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:13 pm -
3 stops27h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Multiple Airlines logo]()
$163
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/281:48 pm -
1 stop17h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Allegiant Air logo]()
$170
Find flight deals from Ohio to Knoxville
Keep the following information in mind while searching for Ohio to Knoxville flight deals. Data was last updated October 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $225 (Kiwi.com) |
One-way from | $104 (Kiwi.com) |
Popular in | October |
Cheapest in | February |
Average price | $720 |
Cheapflights Fare Finder
Customize your flight search to find flights from Ohio to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
Use the filters below to find and compare flights from Ohio to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ClevelandKnoxville
CLE Cleveland Hopkins Intl - TYS Knoxville McGhee Tyson
CLETYS
Cleveland Hopkins Intl
Tue 11/24
7:05 am-1:55 pm
1 stop6h 50m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$120
ClevelandKnoxville
CLE Cleveland Hopkins Intl - TYS Knoxville McGhee Tyson
CLETYS
Cleveland Hopkins Intl
Thu 11/19
11:13 am-5:22 pm
1 stop6h 09m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$120
ClevelandKnoxville
CLE Cleveland Hopkins Intl - TYS Knoxville McGhee Tyson
CLETYS
Cleveland Hopkins Intl
Sat 10/31
9:59 pm-2:22 pm
2 stops40h 23m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$131
CincinnatiKnoxville
CVG Cincinnati Cinci./N. Kentucky - TYS Knoxville McGhee Tyson
CVGTYS
Cincinnati Cinci./N. Kentucky
Thu 11/19
7:10 am-3:01 pm
1 stop7h 51m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$148
ClevelandKnoxville
CLE Cleveland Hopkins Intl - TYS Knoxville McGhee Tyson
CLETYS
Cleveland Hopkins Intl
Fri 11/20
8:05 am-2:55 pm
1 stop6h 50m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$152
CincinnatiKnoxville
CVG Cincinnati Cinci./N. Kentucky - TYS Knoxville McGhee Tyson
CVGTYS
Cincinnati Cinci./N. Kentucky
Fri 11/27
8:05 am-1:55 pm
1 stop5h 50m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$152
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Wed 11/11
6:13 pm-10:05 pm
3 stops27h 52m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$163
ClevelandKnoxville
CLE Cleveland Hopkins Intl - TYS Knoxville McGhee Tyson
CLETYS
Cleveland Hopkins Intl
Mon 11/2
9:59 pm-10:05 am
3 stops36h 06m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$180
CincinnatiKnoxville
CVG Cincinnati Cinci./N. Kentucky - TYS Knoxville McGhee Tyson
CVGTYS
Cincinnati Cinci./N. Kentucky
Sat 11/28
7:59 pm-11:57 pm
1 stop3h 58m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$184
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Thu 11/12
9:09 am-10:05 pm
3 stops12h 56m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$187
Showing 1-10 of 58 resultsSorted by cheapest first
Best time to book a flight from Ohio to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Ohio with our price prediction graph.
CMH-TYS
CLE-TYS
CVG-TYS
CAK-TYS
DAY-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Ohio to Knoxville
USOH-TYS
CMH-TYS
CLE-TYS
CVG-TYS
CAK-TYS
What is the cheapest month to book a flight from Ohio to Knoxville?
Currently, February is the cheapest month in which you can book a flight from Ohio to Knoxville (average of $271). Flying from Ohio to Knoxville in October is currently the most expensive (average of $549). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Ohio to Knoxville?
Airfare is below average for this route at the moment.
Ohio to Knoxville flights typically cost between $372 and $728 in November.The cheapest round-trip price found within the last 5 days was $239 on American Airlines (Nov 10-Nov 11).
Related info for your journey
Find useful and relevant information for your journey from Ohio to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Newport
Bryson City
Murphy
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Ohio to Knoxville
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Complete your trip
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Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 25, 2026.
Ohio and Knoxville flights
Browse other Ohio and Knoxville flight options. Last updated on October 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Ohio to Knoxville flights
Consider these flights traveling from Ohio to Knoxville.
Top 4 airlines flying from Ohio to Knoxville
Discover the top 4 airlines that operate flights from Ohio to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$232 | Average$395 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$263 | Average$316 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$266 | Average$364 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$266 | Average$383 | FlexibilityNo cancel fee | On-time69% |