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Knoxville

$76+ Cheap flights from Ohio to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/18. Fares are subject to change and may not be available on all flights or dates of travel.
CVG — TYS
May 23 — May 301
Sat 5/23
Sat 5/30
1 adult, Economy
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Cheap flight deals from Ohio to Knoxville

Cheapest flights from Ohio to Knoxville
Explore the most affordable flight options available from Ohio to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 23, 2026.

This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/34:40 pm
CAK
-
TYS
1 stop5h 17m
Multiple Airlines
Thu 5/712:55 pm
TYS
-
CAK
1 stop11h 02m
Multiple Airlines
Deal found 4/21$171
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/310:10 pm
DTW
-
TYS
1 stop23h 38m
Multiple Airlines
Sun 5/1011:27 am
TYS
-
DTW
1 stop24h 22m
Multiple Airlines
Deal found 4/19$184
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/410:43 am
CMH
-
TYS
1 stop6h 47m
Multiple Airlines
Fri 5/81:15 pm
TYS
-
CMH
1 stop6h 38m
Multiple Airlines
Deal found 4/19$189
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/291:55 pm
CAK
-
TYS
1 stop8h 06m
Allegiant Air
Thu 6/47:15 am
TYS
-
CAK
1 stop11h 50m
Allegiant Air
Deal found 4/20$189
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/314:36 pm
CAK
-
TYS
1 stop5h 24m
Allegiant Air
Mon 8/312:40 pm
TYS
-
CAK
1 stop8h 51m
Allegiant Air
Deal found 4/19$190
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/78:00 am
PIT
-
TYS
1 stop14h 20m
Multiple Airlines
Mon 5/111:15 pm
TYS
-
PIT
1 stop6h 05m
Multiple Airlines
Deal found 4/22$192
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:50 am
CLE
-
TYS
1 stop8h 40m
Multiple Airlines
Fri 5/81:15 pm
TYS
-
CLE
1 stop9h 56m
Multiple Airlines
Deal found 4/18$196
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/291:55 pm
CAK
-
TYS
1 stop8h 06m
Multiple Airlines
Tue 6/25:05 pm
TYS
-
CAK
1 stop21h 50m
Multiple Airlines
Deal found 4/20$197
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:05 pm
DTW
-
TYS
2 stops18h 08m
Multiple Airlines
Mon 6/112:55 pm
TYS
-
DTW
1 stop22h 54m
Multiple Airlines
Deal found 4/21$197
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/310:10 pm
DTW
-
TYS
1 stop20h 05m
Multiple Airlines
Thu 5/711:27 am
TYS
-
DTW
1 stop24h 22m
Multiple Airlines
Deal found 4/18$199
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/291:55 pm
CAK
-
TYS
1 stop8h 06m
Allegiant Air
Sat 5/305:46 pm
TYS
-
CAK
1 stop17h 37m
Allegiant Air
Deal found 4/20$200
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/12:12 pm
CVG
-
TYS
1 stop26h 03m
Multiple Airlines
Mon 6/812:40 pm
TYS
-
CVG
2 stops22h 34m
Multiple Airlines
Deal found 4/18$200

Find flight deals from Ohio to Knoxville

Keep the following information in mind while searching for Ohio to Knoxville flight deals. Data was last updated April 23, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$171
(Kiwi.com)

One-way from

$76
(Frontier)

Popular in

November

Cheapest in

February

Average price

$385
Provider with most accurate pricing for Cleveland Hopkins Intl-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Knoxville McGhee Tyson flights.
Search Deals
From Ohio to Knoxville McGhee Tyson
Search Deals
One-way flight from Ohio to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 20% potential increase in price ($91 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Ohio to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 23, 2026.
Use the filters below to find and compare flights from Ohio to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Tue 5/19

6:05 am-9:34 am

1 stop3h 29m

Knoxville McGhee Tyson

Tue 5/26

5:40 am-9:05 am

1 stop3h 25m

$233

AkronKnoxville

CAK - TYS

CAKTYS

Akron/Canton

Mon 5/18

12:10 pm-9:48 pm

1 stop9h 38m

Knoxville McGhee Tyson

Mon 5/25

7:24 pm-9:04 pm

1 stop25h 40m

$243

CincinnatiKnoxville

CVG - TYS

CVGTYS

Cincinnati Cinci./N. Kentucky

Mon 5/11

9:30 pm-9:40 am

1 stop12h 10m

Knoxville McGhee Tyson

Thu 5/14

9:40 pm-9:36 pm

1 stop23h 56m

$248

CincinnatiKnoxville

CVG - TYS

CVGTYS

Cincinnati Cinci./N. Kentucky

Thu 7/9

6:29 pm-2:58 pm

1 stop20h 29m

Knoxville McGhee Tyson

Mon 7/13

7:20 pm-11:14 am

2 stops15h 54m

$249

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Thu 5/14

6:00 am-8:50 pm

1 stop14h 50m

Knoxville McGhee Tyson

Fri 5/15

1:15 pm-7:53 pm

1 stop6h 38m

$266

CincinnatiKnoxville

CVG - TYS

CVGTYS

Cincinnati Cinci./N. Kentucky

Wed 5/20

1:48 pm-2:56 pm

2 stops25h 08m

Knoxville McGhee Tyson

Wed 5/27

1:01 pm-8:48 am

1 stop19h 47m

$268

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Tue 5/12

4:10 pm-8:50 pm

1 stop4h 40m

Knoxville McGhee Tyson

Tue 5/19

12:50 pm-9:30 pm

2 stops8h 40m

$274

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Wed 9/9

6:25 am-2:20 pm

2 stops7h 55m

Knoxville McGhee Tyson

Mon 9/14

8:25 am-8:50 pm

2 stops12h 25m

$275

AkronKnoxville

CAK - TYS

CAKTYS

Akron/Canton

Wed 5/20

1:55 pm-8:45 pm

1 stop6h 50m

Knoxville McGhee Tyson

Wed 6/3

8:20 am-1:26 pm

1 stop5h 06m

$304

CincinnatiKnoxville

CVG - TYS

CVGTYS

Cincinnati Cinci./N. Kentucky

Thu 5/28

9:01 pm-2:27 pm

1 stop17h 26m

Knoxville McGhee Tyson

Sun 5/31

6:03 pm-11:28 pm

1 stop5h 25m

$305

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/22

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Ohio to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to Knoxville

How far ahead should I book a flight from Ohio to Knoxville?

The price you pay for your flight from Ohio to Knoxville may vary depending on when you book. For the best chance of a lower fare, look to book 80 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Ohio to Knoxville?

Currently, July is the cheapest month in which you can book a flight from Ohio to Knoxville (average of $165). Flying from Ohio to Knoxville in March is currently the most expensive (average of $243). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Ohio to Knoxville?

Related info for your journey

Find useful and relevant information for your journey from Ohio to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Ohio?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to Knoxville from Ohio.

  • How long is the flight from Ohio to Knoxville?

    Departing from Ohio to Knoxville will take you 3h 29m. The distance from Ohio to Knoxville is about 296 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Ohio to Knoxville one-way?

    The cheapest airlines for a one-way flight from Ohio to Knoxville are United Airlines ($121), American Airlines ($139), and Delta ($140).

  • What are the most popular routes from Ohio to Knoxville?

    Most travelers choose Detroit Metropolitan Wayne County - Knoxville McGhee Tyson, Pittsburgh - Knoxville McGhee Tyson or Cleveland Hopkins Intl - Knoxville McGhee Tyson when deciding on the best route from Ohio to Knoxville.

  • Can I find deals for flights from Ohio to Knoxville that include hotel bookings?

    Yes. In addition to deals on Ohio to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to Knoxville.

  • Can I find deals for business class flights from Ohio to Knoxville?

    Yes. Cheapflights offers flight deals from Ohio to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ohio to Knoxville?

    Currently, July is the cheapest month in which you can book a flight from Ohio to Knoxville (average of $165). Flying from Ohio to Knoxville in March is currently the most expensive (average of $243). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge

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Top 4 airlines flying from Ohio to Knoxville

Discover the top 4 airlines that operate flights from Ohio to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 23, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$213Average$390FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$218Average$361FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$235Average$390FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$263Average$316FlexibilityNo cancel feeOn-time63%

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