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$95+ Cheap flights from New Orleans to Knoxville (MSY - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/30. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — TYS
Nov 26 — Dec 31
Wed 11/26
Wed 12/3
1 adult, Economy
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Cheapflights Tip: The best prices from New Orleans Louis Armstrong to Knoxville McGhee Tyson are usually found in July or January, booked 70 days in advance, depart on a Wednesday or Tuesday and return on a Saturday

Cheap flight deals from New Orleans to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from New Orleans (MSY) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 27, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$184
(Kiwi.com)

One-way from

$95
(Kiwi.com)

Popular in

December

Cheapest in

July

Average price

$394
Provider with most accurate pricing for New Orleans Louis Armstrong-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for New Orleans Louis Armstrong-Knoxville McGhee Tyson flights.
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From New Orleans Louis Armstrong to Knoxville McGhee Tyson
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One-way flight from New Orleans Louis Armstrong to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 4% potential increase in price ($14 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from New Orleans to Knoxville

Cheapest flights from New Orleans to Knoxville
Explore the most affordable flight options available from New Orleans to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/146:00 amMSY - TYS
1 stop15h 56mMultiple Airlines
Mon 11/179:09 pmTYS - MSY
1 stop16h 53mMultiple Airlines
Deal found 10/26$184
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/51:52 pmMSY - TYS
1 stop6h 57mMultiple Airlines
Sun 12/75:23 pmTYS - MSY
2 stops24h 04mMultiple Airlines
Deal found 10/25$220
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/108:59 pmMSY - TYS
1 stop12h 35mMultiple Airlines
Fri 11/146:42 pmTYS - MSY
2 stops42h 47mMultiple Airlines
Deal found 10/26$226
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/112:30 pmMSY - TYS
1 stop24h 12mMultiple Airlines
Thu 11/135:38 pmTYS - MSY
1 stop15h 57mMultiple Airlines
Deal found 10/27$230
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/113:21 pmMSY - TYS
2 stops23h 21mMultiple Airlines
Tue 11/1811:24 amTYS - MSY
1 stop23h 41mMultiple Airlines
Deal found 10/27$248
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/38:59 pmMSY - TYS
1 stop12h 34mMultiple Airlines
Mon 11/106:11 pmTYS - MSY
1 stop19h 51mMultiple Airlines
Deal found 10/26$249

Cheapflights Fare Finder

 
Customize your flight search to find flights from New Orleans to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 27, 2025.
Use the filters below to find and compare flights from New Orleans to Knoxville that are best for you.

Fly from

New Orleans

Fly to

Knoxville

Route

Depart

Return

Price

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Fri 11/14

6:31 pm-8:16 am

1 stop12h 45m

Knoxville McGhee Tyson

Mon 11/17

9:29 pm-6:52 am

1 stop10h 23m

$189

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Tue 11/11

2:30 pm-3:42 pm

1 stop24h 12m

Knoxville McGhee Tyson

Thu 11/13

5:38 pm-8:35 am

1 stop15h 57m

$230

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Fri 12/5

5:20 am-9:49 pm

1 stop15h 29m

Knoxville McGhee Tyson

Sun 12/7

7:11 pm-8:22 am

1 stop14h 11m

$243

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Tue 12/2

7:30 am-2:52 pm

1 stop6h 22m

Knoxville McGhee Tyson

Sat 12/6

3:50 pm-6:24 pm

1 stop3h 34m

$251

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Fri 12/12

7:30 am-2:52 pm

1 stop6h 22m

Knoxville McGhee Tyson

Tue 12/16

5:40 am-9:39 am

1 stop4h 59m

$260

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Tue 12/2

7:24 pm-12:03 pm

1 stop15h 39m

Knoxville McGhee Tyson

Sat 12/6

10:15 am-9:42 pm

2 stops12h 27m

$264

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Fri 11/21

5:22 am-9:37 am

1 stop3h 15m

Knoxville McGhee Tyson

Sun 11/23

9:31 am-2:15 pm

1 stop5h 44m

$269

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Thu 11/20

5:22 am-10:45 am

1 stop4h 23m

Knoxville McGhee Tyson

Sun 11/23

12:01 pm-4:53 pm

1 stop5h 52m

$269

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Thu 12/11

5:15 am-11:16 am

1 stop5h 01m

Knoxville McGhee Tyson

Tue 12/16

11:21 am-5:08 pm

1 stop6h 47m

$294

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Thu 12/11

6:20 am-8:33 am

1 stop25h 13m

$107

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Showing 1-10 of 14 results
1
2

Compare providers for flights from New Orleans to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from New Orleans to Knoxville in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on New Orleans-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on New Orleans-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from New Orleans-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on New Orleans-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for New Orleans-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from New Orleans to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from New Orleans with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from New Orleans to Knoxville

How far ahead should I book a flight from New Orleans to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from New Orleans to Knoxville. Price data was last updated on October 24, 2025.

To ensure you get the cheapest price possible for a flight from New Orleans to Knoxville, you should look to book at least 69 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from New Orleans to Knoxville?

Currently, August is the cheapest month in which you can book a flight from New Orleans to Knoxville (average of $149). Flying from New Orleans to Knoxville in September is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MSY to TYS?

Find hourly flight availability from New Orleans to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 27, 2025.

One of the essential ways to save on airfare from New Orleans to Knoxville is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the afternoon could potentially save you up to 12% on airfare.

How much does it cost to fly round-trip from New Orleans to Knoxville?

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated October 27, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from New Orleans to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,996 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,996 reviews
Delta
7.9
Good
7,996 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,997 reviews
Delta
7.9
Good
7,996 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,033 reviews
Delta
7.9
Good
7,996 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from New Orleans to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from New Orleans to Knoxville?

    For as low as $251, Delta can have you in Knoxville from New Orleans in 6h 22m. New Orleans and Knoxville are separated by a distance of 541 mi.

  • What are the cheapest airlines flying from New Orleans to Knoxville round-trip?

    According to our current data, United Airlines ($198), American Airlines ($246), and Delta ($248) offers the cheapest pricing from New Orleans to Knoxville. You may be able to fly from New Orleans to Knoxville for 39% less than the average price by searching for these airlines.

  • Can I find deals for flights from New Orleans to Knoxville that include hotel bookings?

    Yes. In addition to deals on New Orleans to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from New Orleans to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from New Orleans to Knoxville.

  • Can I find deals for business class flights from New Orleans to Knoxville?

    Yes. Cheapflights offers flight deals from New Orleans to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from New Orleans to Knoxville?

    Currently, August is the cheapest month in which you can book a flight from New Orleans to Knoxville (average of $149). Flying from New Orleans to Knoxville in September is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Crossville
Corbin
Bryson City
Alcoa
Oak Ridge
Murphy

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Top 3 airlines flying from New Orleans to Knoxville

Discover the top 3 airlines that operate flights from New Orleans to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 27, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$198Average$368FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$246Average$335FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$362FlexibilityNo cancel feeOn-timeN/A

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