What are the cheapest airlines flying from New Orleans to Knoxville round-trip?

According to our current data, American Airlines ($199), and Delta ($249) offers the cheapest pricing from New Orleans to Knoxville. You may be able to fly from New Orleans to Knoxville for 41% less than the average price by searching for these airlines.

What is the cheapest day to fly from New Orleans to Knoxville?

Travelers seeking maximum savings on their New Orleans to Knoxville flight should consider departing on Friday evenings when fares are most often at their lowest. Monday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

What are the most popular airlines that fly from New Orleans to Knoxville?

Before booking your flight from New Orleans to Knoxville check out the most popular airlines for this route: American Airlines, Delta or United Airlines.

What is the cheapest day to fly round-trip from New Orleans to Knoxville?

It’s generally more expensive to depart on a Tuesday, if you have to leave on this day you can still search on Cheapflights to find great options that meet your needs.

How far in advance should I book a flight from New Orleans to Knoxville?

Travelers have found it’s best to book a flight 53 days in advance to save up to 68% compared to booking the same week of travel. As your travel date approaches, the cost of this flight route may potentially increase. While opting to book 53 days out may not be an option for all, there are still additional ways to secure a deal in the near future. You might find a flight from New Orleans to Knoxville 1-2 weeks in advance for as low as $251, or $353 for flights within the next 24 hours.

What is the cheapest month to fly from New Orleans to Knoxville?

Due to multiple factors, expect to potentially pay more when booking in December. For low rates, January can be a great choice for travel to Knoxville. Flights to Knoxville from New Orleans in January are about $339 on average during January, but can be found for as low as $220.

Can I find deals for flights from New Orleans to Knoxville that include hotel bookings?

Yes. In addition to deals on New Orleans to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from New Orleans to Knoxville?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from New Orleans to Knoxville.

Can I find deals for business class flights from New Orleans to Knoxville?

Yes. Cheapflights offers flight deals from New Orleans to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$91+ Flights from New Orleans to Knoxville

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1. Tell us where you want to go

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2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

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Cheapflights Tip: The best prices from New Orleans Louis Armstrong to Knoxville McGhee Tyson are usually found in January or April, booked 68 days in advance, depart on a Wednesday or Tuesday and return on a Saturday

Cheap flight deals from New Orleans to Knoxville

Round-trip from	$199 (American Airlines)
One-way from	$91 (Mytrip)
Popular in	December
Cheapest in	January
Average price	$293

From New Orleans Louis Armstrong to Knoxville McGhee Tyson

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One-way flight from New Orleans Louis Armstrong to Knoxville McGhee Tyson

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Highest demand for flights based on searches. 5% potential increase in price ($17 potential increase over avg. RT price).

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Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).

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Average for round-trip flights in July 2025

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Find flight deals from New Orleans to Knoxville

Cheapest flights from New Orleans to Knoxville
Explore the most affordable flight options available from New Orleans to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2025.

Sat 8/3010:54 amMSY - TYS

1 stop5h 45mAmerican Airlines

Sun 8/316:39 pmTYS - MSY

1 stop4h 45mAmerican Airlines

Deal found 7/28

$199

Thu 8/218:21 pmMSY - TYS

1 stop13h 13mMultiple Airlines

Sun 8/249:12 pmTYS - MSY

1 stop11h 47mMultiple Airlines

Deal found 7/26

$216

Sat 9/65:03 pmMSY - TYS

1 stop5h 45mDelta

Thu 9/111:52 pmTYS - MSY

1 stop5h 05mDelta

Deal found 7/28

$249

Best flights from New Orleans to Knoxville
Discover carefully curated flight deals from New Orleans to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 28, 2025.

Sat 8/3010:54 amMSY - TYS

1 stop5h 45mAmerican Airlines

Sun 8/316:39 pmTYS - MSY

1 stop4h 45mAmerican Airlines

Deal found 7/28

$199

Mon 9/155:20 amMSY - TYS

1 stop11h 14mMultiple Airlines

Fri 9/191:22 pmTYS - MSY

1 stop7h 34mMultiple Airlines

Deal found 7/28

$209

Sat 9/65:03 pmMSY - TYS

1 stop5h 45mDelta

Thu 9/111:52 pmTYS - MSY

1 stop5h 05mDelta

Deal found 7/28

$249

Last-minute flights from New Orleans to Knoxville
Discover last-minute flight deals from New Orleans to Knoxville. Data last updated July 28, 2025 and is based on user searches.

Mon 8/45:25 amMSY - TYS

1 stop3h 25mDelta

Thu 8/710:59 amTYS - MSY

1 stop3h 06mDelta

Deal found 7/26

$749

Thu 8/218:21 pmMSY - TYS

1 stop13h 13mMultiple Airlines

Sun 8/249:12 pmTYS - MSY

1 stop11h 47mMultiple Airlines

Deal found 7/26

$216

Wed 8/276:25 amMSY - TYS

1 stop3h 17mDelta

Tue 9/26:14 pmTYS - MSY

1 stop5h 46mDelta

Deal found 7/28

$249

Wed 8/272:16 pmMSY - TYS

1 stop4h 37mUnited Airlines

Tue 9/27:25 pmTYS - MSY

2 stops18h 52mUnited Airlines

Deal found 7/28

$458

Sat 8/3010:54 amMSY - TYS

1 stop5h 45mAmerican Airlines

Sun 8/316:39 pmTYS - MSY

1 stop4h 45mAmerican Airlines

Deal found 7/28

$199

One-way flights from New Orleans to Knoxville
Search for one-way flight options from New Orleans to Knoxville. Find affordable one-way fares based on user searches. Data last updated July 28, 2025.

Mon 8/255:20 amMSY - TYS

1 stop11h 18mMultiple Airlines

Deal found 7/26

$91

Thu 9/186:14 pmMSY - TYS

1 stop4h 37mAmerican Airlines

Deal found 7/26

$239

Mon 9/2911:50 amMSY - TYS

2 stops21h 39mUnited Airlines

Deal found 7/27

$305

Cheapflights Fare Finder

Use the filters below to find and compare flights from New Orleans to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Sat 8/30

10:54 am-5:39 pm

1 stop5h 45m

Knoxville McGhee Tyson

Sun 8/31

6:39 pm-10:24 pm

1 stop4h 45m

$199

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Thu 8/21

8:21 pm-10:34 am

1 stop13h 13m

Knoxville McGhee Tyson

Sun 8/24

9:12 pm-7:59 am

1 stop11h 47m

$216

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Sat 9/6

5:03 pm-11:48 pm

1 stop5h 45m

Knoxville McGhee Tyson

Thu 9/11

1:52 pm-5:57 pm

1 stop5h 05m

$249

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Mon 8/25

5:20 am-5:38 pm

1 stop11h 18m

$91

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Thu 9/18

6:14 pm-11:51 pm

1 stop4h 37m

$239

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Mon 9/29

11:50 am-10:29 am

2 stops21h 39m

$305

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/26

Best time to book a flight from New Orleans to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from New Orleans with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from New Orleans to Knoxville

How far ahead should I book a flight from New Orleans to Knoxville?

To ensure you get the cheapest price possible for a flight from New Orleans to Knoxville, you should look to book at least 52 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from New Orleans to Knoxville?

Currently, January is the cheapest month in which you can book a flight from New Orleans to Knoxville (average of $295). Flying from New Orleans to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MSY to TYS?

One of the essential ways to save on airfare from New Orleans to Knoxville is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the afternoon could potentially save you up to 13% on airfare.

Reviews of airlines servicing Knoxville

Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from New Orleans to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,975 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,975 reviews

Delta

8.0

Very good

7,975 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

United Airlines

7.4

Good

8,892 reviews

Delta

8.0

Very good

7,975 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,975 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What are the cheapest airlines flying from New Orleans to Knoxville round-trip?
According to our current data, American Airlines ($199), and Delta ($249) offers the cheapest pricing from New Orleans to Knoxville. You may be able to fly from New Orleans to Knoxville for 41% less than the average price by searching for these airlines.
Can I find deals for flights from New Orleans to Knoxville that include hotel bookings?
Yes. In addition to deals on New Orleans to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from New Orleans to Knoxville?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from New Orleans to Knoxville.
Can I find deals for business class flights from New Orleans to Knoxville?
Yes. Cheapflights offers flight deals from New Orleans to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from New Orleans to Knoxville?
Currently, January is the cheapest month in which you can book a flight from New Orleans to Knoxville (average of $295). Flying from New Orleans to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Morristown

Corbin

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Alcoa

Oak Ridge

Murphy

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Other flights to Knoxville

Top 3 airlines flying from New Orleans to Knoxville

Airline	Cheapest	Average	Flexibility	On-time
United Airlines	Cheapest$198	Average$369	FlexibilityNo cancel fee	On-time69%
Delta	Cheapest$218	Average$328	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$226	Average$336	FlexibilityNo cancel fee	On-time71%

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$91+ Cheap flights from New Orleans to Knoxville (MSY - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/25. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from New Orleans to Knoxville with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from New Orleans Louis Armstrong to Knoxville McGhee Tyson are usually found in January or April, booked 68 days in advance, depart on a Wednesday or Tuesday and return on a Saturday

Cheap flight deals from New Orleans to Knoxville

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from New Orleans to Knoxville

Cheapest flights from New Orleans to KnoxvilleExplore the most affordable flight options available from New Orleans to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2025.

Explore the most affordable flight options available from New Orleans to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from New Orleans to Knoxville that are best for you.

Best time to book a flight from New Orleans to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from New Orleans with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from New Orleans to Knoxville

How far ahead should I book a flight from New Orleans to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from New Orleans to Knoxville. Price data was last updated on July 25, 2025.

What is the cheapest month to book a flight from New Orleans to Knoxville?

What is the cheapest time of day to fly from MSY to TYS?

Find hourly flight availability from New Orleans to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 28, 2025.

Reviews of airlines servicing Knoxville

Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from New Orleans to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from New Orleans to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from New Orleans to Knoxville round-trip?

Can I find deals for flights from New Orleans to Knoxville that include hotel bookings?

How can I find direct flights from New Orleans to Knoxville?

Can I find deals for business class flights from New Orleans to Knoxville?

What is the cheapest month to book a flight from New Orleans to Knoxville?

Traveling to a place near Knoxville?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for New Orleans to Knoxville

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Top 3 airlines flying from New Orleans to Knoxville

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Cheapest flights from New Orleans to Knoxville
Explore the most affordable flight options available from New Orleans to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2025.