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$105+ Cheap flights from New Orleans to Knoxville (MSY - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/4. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — TYS
Feb 20 — Feb 271
Fri 2/20
Fri 2/27
1 adult, Economy
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Cheap flight deals from New Orleans to Knoxville

Cheapest flights from New Orleans to Knoxville
Explore the most affordable flight options available from New Orleans to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/48:57 pm
MSY
-
TYS
1 stop20h 31m
Multiple Airlines
Sat 2/75:59 pm
TYS
-
MSY
1 stop15h 23m
Multiple Airlines
Deal found 1/21$186
This Kiwi.com deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/262:34 pm
MSY
-
TYS
1 stop26h 32m
Multiple Airlines
Sun 3/19:42 pm
TYS
-
MSY
1 stop17h 11m
Multiple Airlines
Deal found 1/21$211
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/146:10 pm
MSY
-
TYS
2 stops27h 15m
Multiple Airlines
Wed 2/189:00 am
TYS
-
MSY
1 stop10h 55m
Multiple Airlines
Deal found 1/20$213
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/287:42 pm
MSY
-
TYS
1 stop11h 57m
Multiple Airlines
Sat 2/75:59 pm
TYS
-
MSY
1 stop15h 23m
Multiple Airlines
Deal found 1/20$215
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/62:40 pm
MSY
-
TYS
1 stop6h 44m
Allegiant Air
Sun 3/89:32 pm
TYS
-
MSY
1 stop17h 18m
Allegiant Air
Deal found 1/20$218
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/48:57 pm
MSY
-
TYS
1 stop20h 31m
Multiple Airlines
Sun 2/88:00 am
TYS
-
MSY
1 stop25h 22m
Multiple Airlines
Deal found 1/20$220
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/611:10 am
MSY
-
TYS
1 stop10h 11m
Multiple Airlines
Sun 2/88:00 am
TYS
-
MSY
1 stop25h 22m
Multiple Airlines
Deal found 1/20$224
This Kiwi.com deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/25:11 pm
MSY
-
TYS
1 stop5h 28m
Multiple Airlines
Sun 4/58:20 am
TYS
-
MSY
1 stop9h 11m
Multiple Airlines
Deal found 1/21$228
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/277:42 pm
MSY
-
TYS
1 stop19h 15m
Multiple Airlines
Sun 2/159:44 pm
TYS
-
MSY
1 stop18h 16m
Multiple Airlines
Deal found 1/20$230
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/295:59 pm
MSY
-
TYS
2 stops24h 57m
Multiple Airlines
Sat 2/75:59 pm
TYS
-
MSY
1 stop15h 23m
Multiple Airlines
Deal found 1/20$234
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/287:42 pm
MSY
-
TYS
1 stop11h 57m
Multiple Airlines
Sun 2/88:00 am
TYS
-
MSY
1 stop25h 22m
Multiple Airlines
Deal found 1/20$238

Find flight deals from New Orleans to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from New Orleans (MSY) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 21, 2026.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$186
(Kiwi.com)

One-way from

$105
(Kiwi.com)

Popular in

December

Cheapest in

July

Average price

$298
Provider with most accurate pricing for New Orleans Louis Armstrong-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for New Orleans Louis Armstrong-Knoxville McGhee Tyson flights.
Search Deals
From New Orleans Louis Armstrong to Knoxville McGhee Tyson
Search Deals
One-way flight from New Orleans Louis Armstrong to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($28 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from New Orleans to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
Use the filters below to find and compare flights from New Orleans to Knoxville that are best for you.

Fly from

New Orleans

Fly to

Knoxville

Route

Depart

Return

Price

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Wed 2/4

3:43 pm-6:28 pm

2 stops25h 45m

Knoxville McGhee Tyson

Sat 2/7

5:59 pm-8:22 am

1 stop15h 23m

$207

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Thu 4/2

5:11 pm-11:39 pm

1 stop5h 28m

Knoxville McGhee Tyson

Sun 4/5

8:20 am-4:31 pm

1 stop9h 11m

$228

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Sat 2/21

6:52 am-10:10 pm

2 stops38h 18m

Knoxville McGhee Tyson

Fri 2/27

6:51 pm-1:39 pm

1 stop19h 48m

$245

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Thu 2/26

10:43 am-10:07 pm

2 stops10h 24m

Knoxville McGhee Tyson

Sun 3/1

9:42 pm-1:53 pm

1 stop17h 11m

$251

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Thu 3/5

7:27 pm-11:01 am

1 stop14h 34m

Knoxville McGhee Tyson

Mon 3/9

9:36 pm-8:21 am

1 stop11h 45m

$259

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Fri 3/6

6:20 am-6:27 pm

2 stops11h 07m

Knoxville McGhee Tyson

Sun 3/8

9:32 pm-1:50 pm

1 stop17h 18m

$270

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Thu 3/5

11:55 am-9:15 pm

2 stops8h 20m

Knoxville McGhee Tyson

Mon 3/9

7:25 pm-12:10 am

1 stop5h 45m

$304

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Thu 3/19

1:17 pm-5:45 pm

1 stop3h 28m

Knoxville McGhee Tyson

Mon 3/23

5:40 am-10:33 am

1 stop5h 53m

$318

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Fri 4/3

3:30 pm-8:36 am

2 stops16h 06m

Knoxville McGhee Tyson

Sun 4/5

8:20 am-4:31 pm

1 stop9h 11m

$329

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Wed 2/4

8:57 pm-6:28 pm

1 stop20h 31m

$105

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Showing 1-10 of 17 results
1
2

Compare providers for flights from New Orleans to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from New Orleans to Knoxville in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
PricelinePrice Accuracy1 starTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on New Orleans-Knoxville flights, users find the pricing of Mytrip to be most consistent on Cheapflights vs. Mytrip Users can find the same prices on New Orleans-Knoxville flight deals on Cheapflights vs. Mytrip >95% of the time. Price accuracy is based on data collected from New Orleans-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on New Orleans-Knoxville flights, Cheapflights users trust Mytrip the most. Mytrip has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for New Orleans-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from New Orleans to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from New Orleans with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from New Orleans to Knoxville

How far ahead should I book a flight from New Orleans to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from New Orleans to Knoxville. Price data was last updated on January 16, 2026.

To ensure you get the cheapest price possible for a flight from New Orleans to Knoxville, you should look to book at least 69 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from New Orleans to Knoxville?

Currently, August is the cheapest month in which you can book a flight from New Orleans to Knoxville (average of $149). Flying from New Orleans to Knoxville in September is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from New Orleans to Knoxville?

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated January 21, 2026.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from New Orleans to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,089 reviews

Crew

8.5

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,089 reviews
Delta
7.9
Good
8,089 reviews

Crew

8.5

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,191 reviews
Delta
7.9
Good
8,089 reviews

Crew

8.5

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,174 reviews
Delta
7.9
Good
8,089 reviews

Crew

8.5

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from New Orleans to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from New Orleans to Knoxville round-trip?

    According to our current data, United Airlines ($198), American Airlines ($224), and Delta ($248) offers the cheapest pricing from New Orleans to Knoxville. You may be able to fly from New Orleans to Knoxville for 40% less than the average price by searching for these airlines.

  • Can I find deals for flights from New Orleans to Knoxville that include hotel bookings?

    Yes. In addition to deals on New Orleans to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from New Orleans to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from New Orleans to Knoxville.

  • Can I find deals for business class flights from New Orleans to Knoxville?

    Yes. Cheapflights offers flight deals from New Orleans to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from New Orleans to Knoxville?

    Currently, August is the cheapest month in which you can book a flight from New Orleans to Knoxville (average of $149). Flying from New Orleans to Knoxville in September is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Oak Ridge
Murphy

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from New Orleans to Knoxville

Discover the top 3 airlines that operate flights from New Orleans to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$198Average$368FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$224Average$325FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$363FlexibilityNo cancel feeOn-timeN/A

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