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$95+ Cheap flights from New Orleans to Knoxville (MSY - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/14. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — TYS
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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1. Tell us where you want to go

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Cheapflights Tip: The best prices from New Orleans Louis Armstrong to Knoxville McGhee Tyson are usually found in July or January, booked 70 days in advance, depart on a Wednesday or Tuesday and return on a Saturday

Cheap flight deals from New Orleans to Knoxville

Cheapest flights from New Orleans to Knoxville
Explore the most affordable flight options available from New Orleans to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:05 amMSY - TYS
1 stop15h 02mMultiple Airlines
Mon 1/56:30 amTYS - MSY
1 stop18h 25mMultiple Airlines
Deal found 12/9$224
This Kiwi.com deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:05 amMSY - TYS
1 stop15h 02mMultiple Airlines
Sun 1/410:03 pmTYS - MSY
1 stop26h 52mMultiple Airlines
Deal found 12/9$246
This Kiwi.com deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1811:12 amMSY - TYS
1 stop10h 30mMultiple Airlines
Wed 12/245:31 pmTYS - MSY
1 stop16h 16mMultiple Airlines
Deal found 12/9$247
This Kiwi.com deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/173:20 pmMSY - TYS
1 stop15h 58mMultiple Airlines
Wed 12/245:31 pmTYS - MSY
1 stop7h 28mMultiple Airlines
Deal found 12/9$251
This Kiwi.com deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/155:15 amMSY - TYS
1 stop11h 05mMultiple Airlines
Wed 12/2411:08 amTYS - MSY
1 stop13h 51mMultiple Airlines
Deal found 12/9$284
This Kiwi.com deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1811:12 amMSY - TYS
1 stop10h 30mMultiple Airlines
Tue 12/303:20 pmTYS - MSY
1 stop18h 27mMultiple Airlines
Deal found 12/9$288
This Kiwi.com deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/243:10 pmMSY - TYS
1 stop26h 49mMultiple Airlines
Thu 1/112:00 pmTYS - MSY
1 stop26h 16mMultiple Airlines
Deal found 12/9$291

Find flight deals from New Orleans to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from New Orleans (MSY) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$208
(Kiwi.com)

One-way from

$95
(Mytrip)

Popular in

December

Cheapest in

July

Average price

$418
Provider with most accurate pricing for New Orleans Louis Armstrong-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for New Orleans Louis Armstrong-Knoxville McGhee Tyson flights.
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From New Orleans Louis Armstrong to Knoxville McGhee Tyson
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One-way flight from New Orleans Louis Armstrong to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($24 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from New Orleans to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from New Orleans to Knoxville that are best for you.

Fly from

New Orleans

Fly to

Knoxville

Route

Depart

Return

Price

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Thu 1/15

5:11 pm-11:05 pm

1 stop4h 54m

Knoxville McGhee Tyson

Sun 1/18

1:39 pm-3:14 pm

2 stops26h 35m

$215

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Sat 2/14

6:45 pm-11:54 pm

1 stop4h 09m

Knoxville McGhee Tyson

Wed 2/18

5:35 am-9:51 am

1 stop5h 16m

$235

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Thu 1/29

7:42 pm-5:28 pm

2 stops20h 46m

Knoxville McGhee Tyson

Sun 2/1

9:29 am-9:29 pm

1 stop13h 00m

$262

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Thu 12/18

11:12 am-10:42 pm

1 stop10h 30m

Knoxville McGhee Tyson

Wed 12/24

11:08 am-9:02 pm

2 stops10h 54m

$268

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Wed 12/17

3:20 pm-8:18 am

1 stop15h 58m

Knoxville McGhee Tyson

Wed 12/24

11:08 am-9:02 pm

2 stops10h 54m

$272

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Mon 2/23

6:20 am-4:59 pm

1 stop9h 39m

Knoxville McGhee Tyson

Wed 2/25

3:50 pm-9:38 am

2 stops18h 48m

$275

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Wed 1/7

5:24 pm-11:45 pm

1 stop5h 21m

Knoxville McGhee Tyson

Wed 1/14

5:40 am-10:45 am

1 stop6h 05m

$277

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Mon 1/5

3:01 pm-9:37 pm

1 stop5h 36m

Knoxville McGhee Tyson

Mon 1/19

7:15 am-8:21 am

2 stops26h 06m

$283

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Mon 12/15

5:15 am-5:20 pm

1 stop11h 05m

Knoxville McGhee Tyson

Wed 12/24

11:08 am-11:59 pm

1 stop13h 51m

$284

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Sat 1/17

8:48 am-3:56 pm

1 stop6h 08m

Knoxville McGhee Tyson

Mon 1/19

6:51 pm-10:59 pm

1 stop5h 08m

$286

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/9

Showing 1-10 of 17 results
1
2

Compare providers for flights from New Orleans to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from New Orleans to Knoxville in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on New Orleans-Knoxville flights, users find the pricing of Mytrip to be most consistent on Cheapflights vs. Mytrip Users can find the same prices on New Orleans-Knoxville flight deals on Cheapflights vs. Mytrip >95% of the time. Price accuracy is based on data collected from New Orleans-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on New Orleans-Knoxville flights, Cheapflights users trust Mytrip the most. Mytrip has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for New Orleans-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from New Orleans to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from New Orleans with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from New Orleans to Knoxville

How far ahead should I book a flight from New Orleans to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from New Orleans to Knoxville. Price data was last updated on December 5, 2025.

To ensure you get the cheapest price possible for a flight from New Orleans to Knoxville, you should look to book at least 69 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from New Orleans to Knoxville?

Currently, August is the cheapest month in which you can book a flight from New Orleans to Knoxville (average of $149). Flying from New Orleans to Knoxville in September is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MSY to TYS?

Find hourly flight availability from New Orleans to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

One of the essential ways to save on airfare from New Orleans to Knoxville is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the afternoon could potentially save you up to 12% on airfare.

How much does it cost to fly round-trip from New Orleans to Knoxville?

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated December 12, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from New Orleans to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,008 reviews

Boarding

8.1

Food

7.3

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,008 reviews
Delta
7.9
Good
8,008 reviews

Boarding

8.1

Food

7.3

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,095 reviews
Delta
7.9
Good
8,008 reviews

Boarding

8.1

Food

7.3

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,050 reviews
Delta
7.9
Good
8,008 reviews

Boarding

8.1

Food

7.3

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from New Orleans to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from New Orleans to Knoxville?

    For as low as $235, American Airlines can have you in Knoxville from New Orleans in 4h 09m. New Orleans and Knoxville are separated by a distance of 541 mi.

  • What are the cheapest airlines flying from New Orleans to Knoxville round-trip?

    According to our current data, United Airlines ($198), American Airlines ($228), and Delta ($248) offers the cheapest pricing from New Orleans to Knoxville. You may be able to fly from New Orleans to Knoxville for 40% less than the average price by searching for these airlines.

  • Can I find deals for flights from New Orleans to Knoxville that include hotel bookings?

    Yes. In addition to deals on New Orleans to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from New Orleans to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from New Orleans to Knoxville.

  • Can I find deals for business class flights from New Orleans to Knoxville?

    Yes. Cheapflights offers flight deals from New Orleans to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from New Orleans to Knoxville?

    Currently, August is the cheapest month in which you can book a flight from New Orleans to Knoxville (average of $149). Flying from New Orleans to Knoxville in September is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Oak Ridge
Murphy

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Top 3 airlines flying from New Orleans to Knoxville

Discover the top 3 airlines that operate flights from New Orleans to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$198Average$369FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$228Average$338FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$342FlexibilityNo cancel feeOn-timeN/A

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