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Knoxville

$80+ Cheap flights from Minnesota to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/2. Fares are subject to change and may not be available on all flights or dates of travel.
MSP — TYS
Feb 27 — Mar 61
Fri 2/27
Fri 3/6
1 adult, Economy
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Cheap flight deals from Minnesota to Knoxville

Cheapest flights from Minnesota to Knoxville
Explore the most affordable flight options available from Minnesota to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 28, 2026.

This Frontier deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/66:45 am
MSP
-
TYS
1 stop7h 45m
Frontier
Mon 2/94:30 pm
TYS
-
MSP
1 stop8h 27m
Frontier
Deal found 1/26$215
This Frontier deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/206:45 am
MSP
-
TYS
1 stop11h 42m
Frontier
Fri 2/276:51 pm
TYS
-
MSP
1 stop6h 06m
Frontier
Deal found 1/26$230
This Priceline deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/26:45 am
MSP
-
TYS
1 stop7h 50m
Frontier
Fri 2/64:25 pm
TYS
-
MSP
1 stop8h 32m
Frontier
Deal found 1/26$236
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/411:37 am
RST
-
TYS
1 stop6h 00m
American Airlines
Tue 4/77:33 pm
TYS
-
RST
1 stop5h 23m
American Airlines
Deal found 1/25$258
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/104:39 pm
RST
-
TYS
1 stop5h 30m
Delta
Fri 2/206:35 am
TYS
-
RST
1 stop5h 23m
Delta
Deal found 1/26$263
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/235:00 am
RST
-
TYS
1 stop4h 45m
American Airlines
Mon 3/25:02 pm
TYS
-
RST
2 stops7h 46m
American Airlines
Deal found 1/25$264
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/103:05 pm
DLH
-
TYS
1 stop4h 47m
United Airlines
Sat 2/146:45 am
TYS
-
DLH
1 stop4h 58m
United Airlines
Deal found 1/26$268
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/295:28 pm
FSD
-
TYS
1 stop5h 28m
American Airlines
Tue 5/55:44 am
TYS
-
FSD
1 stop8h 17m
American Airlines
Deal found 1/26$269
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/104:39 pm
RST
-
TYS
1 stop5h 30m
Delta
Wed 2/185:35 am
TYS
-
RST
2 stops6h 23m
Delta
Deal found 1/26$269
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/166:45 am
MSP
-
TYS
1 stop11h 33m
Frontier
Fri 2/208:12 pm
TYS
-
MSP
1 stop28h 45m
Frontier
Deal found 1/26$287
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/113:05 pm
DLH
-
TYS
1 stop4h 47m
United Airlines
Sun 2/156:45 am
TYS
-
DLH
1 stop4h 58m
United Airlines
Deal found 1/27$287
This Priceline deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:45 am
MSP
-
TYS
1 stop7h 48m
Frontier
Sun 5/34:28 pm
TYS
-
MSP
1 stop8h 30m
Frontier
Deal found 1/26$291

Find flight deals from Minnesota to Knoxville

Keep the following information in mind while searching for Minnesota to Knoxville flight deals. Data was last updated January 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$230
(Frontier)

One-way from

$80
(Frontier)

Popular in

January

Cheapest in

July

Average price

$509

Good round-trip deal

$349 or less

Good one-way deal

$398 or less
Provider with most accurate pricing for Minneapolis St Paul-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Minneapolis St Paul-Knoxville McGhee Tyson flights.
Search Deals
From Minnesota to Knoxville McGhee Tyson
Search Deals
One-way flight from Minnesota to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($48 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals
Price to beat on a round-trip flight from Minnesota to Knoxville McGhee Tyson.
Search Deals
Price to beat on a one-way flight from Minnesota to Knoxville McGhee Tyson.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Minnesota to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
Use the filters below to find and compare flights from Minnesota to Knoxville that are best for you.

Fly from

Minnesota

Fly to

Knoxville

Route

Depart

Return

Price

RochesterKnoxville

RST - TYS

RSTTYS

Rochester

Sat 4/4

11:37 am-6:37 pm

1 stop6h 00m

Knoxville McGhee Tyson

Tue 4/7

7:33 pm-11:56 pm

1 stop5h 23m

$258

RochesterKnoxville

RST - TYS

RSTTYS

Rochester

Tue 2/10

4:39 pm-11:09 pm

1 stop5h 30m

Knoxville McGhee Tyson

Thu 2/19

6:35 am-10:58 am

1 stop5h 23m

$263

RochesterKnoxville

RST - TYS

RSTTYS

Rochester

Tue 2/10

4:39 pm-11:09 pm

1 stop5h 30m

Knoxville McGhee Tyson

Fri 2/20

6:35 am-10:58 am

1 stop5h 23m

$263

RochesterKnoxville

RST - TYS

RSTTYS

Rochester

Mon 2/23

5:00 am-10:45 am

1 stop4h 45m

Knoxville McGhee Tyson

Mon 3/2

5:02 pm-11:48 pm

2 stops7h 46m

$264

DuluthKnoxville

DLH - TYS

DLHTYS

Duluth Intl

Tue 2/10

3:05 pm-8:52 pm

1 stop4h 47m

Knoxville McGhee Tyson

Sat 2/14

6:45 am-10:43 am

1 stop4h 58m

$268

Sioux FallsKnoxville

FSD - TYS

FSDTYS

Sioux Falls Joe Foss Field

Wed 4/29

5:28 pm-11:56 pm

1 stop5h 28m

Knoxville McGhee Tyson

Tue 5/5

5:44 am-1:01 pm

1 stop8h 17m

$269

DuluthKnoxville

DLH - TYS

DLHTYS

Duluth Intl

Wed 2/11

3:05 pm-8:52 pm

1 stop4h 47m

Knoxville McGhee Tyson

Sun 2/15

6:45 am-10:43 am

1 stop4h 58m

$287

MinneapolisKnoxville

MSP - TYS

MSPTYS

Minneapolis St Paul

Sat 4/11

6:15 am-11:40 am

1 stop4h 25m

Knoxville McGhee Tyson

Mon 4/13

8:05 am-3:40 pm

1 stop8h 35m

$298

MinneapolisKnoxville

MSP - TYS

MSPTYS

Minneapolis St Paul

Sat 5/2

6:30 am-3:20 pm

2 stops7h 50m

Knoxville McGhee Tyson

Tue 5/5

8:15 am-2:35 pm

1 stop7h 20m

$298

MinneapolisKnoxville

MSP - TYS

MSPTYS

Minneapolis St Paul

Fri 4/3

7:50 pm-11:03 pm

Nonstop2h 13m

Knoxville McGhee Tyson

Sat 4/11

6:35 am-8:12 am

Nonstop2h 37m

$299

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 52 results
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Best time to book a flight from Minnesota to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Minnesota with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Minnesota to Knoxville

What is the cheapest month to book a flight from Minnesota to Knoxville?

Currently, June is the cheapest month in which you can book a flight from Minnesota to Knoxville (average of $49). Flying from Minnesota to Knoxville in March is currently the most expensive (average of $292). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MN to TYS?

Find hourly flight availability from Minnesota to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 28, 2026.

One of the essential ways to save on airfare from Minnesota to Knoxville is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the morning could potentially save you up to 67% on airfare.

Weekly flight availability from Minnesota to Knoxville

Explore weekly flight availability from Minnesota to Knoxville. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated January 28, 2026.

The most flights from USMN to TYS are scheduled on a Monday (4 on average). You will have fewer flight options on Wednesday, which is when the least amount of flights are scheduled (2 on average).

Related info for your journey

Find useful and relevant information for your journey from Minnesota to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Minnesota?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to Knoxville from Minnesota.

  • How long is the flight from Minnesota to Knoxville?

    Departing from Minnesota to Knoxville will take you 4h 47m. There are 871 mi between Minnesota and Knoxville. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Minnesota to Knoxville one-way?

    The cheapest airline one-way is Allegiant Air, with whom users have recently found tickets for as low as $48. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from Minnesota to Knoxville for a low price.

  • What are the most popular routes from Minnesota to Knoxville?

    The most popular flight routes from Minnesota to Knoxville are Minneapolis St Paul - Knoxville McGhee Tyson, Sioux Falls Joe Foss Field - Knoxville McGhee Tyson and Fargo Hector Field - Knoxville McGhee Tyson.

  • What are the most reliable airlines from Minnesota to Knoxville?

    Before booking your flight to Knoxville from Minnesota, check out the most reliable airlines to get you to your destination on time: Delta (79%), KLM (71%), Endeavor Airlines( 69%).

  • What are the cheapest flights from Minnesota to Knoxville?

    On average you can expect to pay $444 for a flight from Minnesota to Knoxville. The cheapest flight overall is $248 while the most popular route, (Minneapolis St Paul - Knoxville McGhee Tyson) is currently priced at $299.

  • Can I find deals for flights from Minnesota to Knoxville that include hotel bookings?

    Yes. In addition to deals on Minnesota to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Minnesota to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Minnesota to Knoxville.

  • Can I find deals for business class flights from Minnesota to Knoxville?

    Yes. Cheapflights offers flight deals from Minnesota to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Minnesota to Knoxville?

    Currently, June is the cheapest month in which you can book a flight from Minnesota to Knoxville (average of $49). Flying from Minnesota to Knoxville in March is currently the most expensive (average of $292). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Oak Ridge
Murphy

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Top 4 airlines flying from Minnesota to Knoxville

Discover the top 4 airlines that operate flights from Minnesota to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$77Average$123FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$287Average$413FlexibilityNo cancel feeOn-time71%
DeltaCheapest$299Average$410FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$311Average$418FlexibilityNo cancel feeOn-time69%

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