How far in advance should I book a flight from Islip, New York to Knoxville?

Find a great deal and save up to 345% by booking at least 54 days prior to your desired departure date, rather than waiting until the week of travel. According to our data, there are a number of flights available from Islip, New York to Knoxville within the next two weeks, with the cheapest ticket starting at $269.

What is the cheapest month to fly from Islip, New York to Knoxville?

The best pricing can be found in the month of January. Prices to Knoxville from Islip, New York average $316. You can even find prices in January for less than $316, as users have found deals to Knoxville from as low as $123. The month of November appears to be one of the more expensive times to travel to Knoxville from Islip, New York. Flying in the targeted month can save you up to 21%.

What is the cheapest time of day to fly from ISP to TYS?

When flying from Islip, New York to Knoxville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Can I find deals for flights from Islip to Knoxville that include hotel bookings?

Yes. In addition to deals on Islip to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Islip to Knoxville?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Islip to Knoxville.

Can I find deals for business class flights from Islip to Knoxville?

Yes. Cheapflights offers flight deals from Islip to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$296+ Flights from Islip, NY to Knoxville

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Islip to Knoxville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Islip to Knoxville

Round-trip from	$659 (Mytrip)
One-way from	$296 (Frontier)
Popular in	November
Cheapest in	January
Average price	$284

From Islip Long Island to Knoxville McGhee Tyson

Search Deals

One-way flight from Islip Long Island to Knoxville McGhee Tyson

Search Deals

Highest demand for flights based on searches. 10% potential increase in price ($36 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($7 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in June 2025

Search Deals

Find flight deals from Islip to Knoxville

Cheapest flights from Islip to Knoxville
Explore the most affordable flight options available from Islip to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

jue. 7/107:30 amISP - TYS

1 stop7h 39mMultiple Airlines

mié. 7/166:40 amTYS - ISP

1 stop6h 44mMultiple Airlines

Deal found 6/10

$659

Best flights from Islip to Knoxville
Discover carefully curated flight deals from Islip to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated junio 12, 2025.

jue. 7/107:30 amISP - TYS

1 stop7h 39mMultiple Airlines

mié. 7/166:40 amTYS - ISP

1 stop6h 44mMultiple Airlines

Deal found 6/10

$659

Last-minute flights from Islip to Knoxville
Discover last-minute flight deals from Islip to Knoxville. Data last updated junio 12, 2025 and is based on user searches.

jue. 7/107:30 amISP - TYS

1 stop7h 39mMultiple Airlines

mié. 7/166:40 amTYS - ISP

1 stop6h 44mMultiple Airlines

Deal found 6/10

$659

One-way flights from Islip to Knoxville
Search for one-way flight options from Islip to Knoxville. Find affordable one-way fares based on user searches. Data last updated junio 12, 2025.

mié. 7/168:37 pmISP - TYS

2 stops19h 52mFrontier

Deal found 6/10

$296

sáb. 7/2611:53 amISP - TYS

3 stops32h 11mMultiple Airlines

Deal found 6/10

$443

Cheapflights Fare Finder

Use the filters below to find and compare flights from Islip to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

IslipKnoxville

ISP - TYS

ISPTYS

Islip Long Island

jue. 7/10

7:30 am-3:09 pm

1 stop7h 39m

Knoxville McGhee Tyson

mié. 7/16

6:40 am-1:24 pm

1 stop6h 44m

$659

IslipKnoxville

ISP - TYS

ISPTYS

Islip Long Island

mié. 7/16

8:37 pm-4:29 pm

2 stops19h 52m

$296

IslipKnoxville

ISP - TYS

ISPTYS

Islip Long Island

sáb. 7/26

11:53 am-8:04 pm

3 stops32h 11m

$443

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Best time to book a flight from Islip to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Islip with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Islip to Knoxville

What is the cheapest month to book a flight from Islip, New York to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Islip, New York to Knoxville (average of $296). Flying from Islip, New York to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Knoxville by month

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Frontier

5.9

Fair

3,295 reviews

Reviews

1 / 20

4.0

Okay

Paulina,Jun 2025

MSY - DEN

The staff in the plane and outside of the plane were very rude. My flight was delayed 3 times which i understand was not the staff’s fault but my boarding pass time was never updated which had multiple people very confused and when I asked the question of why no answer was given. They made a handful of people check their bag and upon entering the plane there was still plenty of room.

Frontier

5.9

Fair

3,295 reviews

Frontier

5.9

Fair

3,295 reviews

Reviews

1 / 20

4.0

Okay

Paulina,Jun 2025

MSY - DEN

Related info for your journey

Can I find deals for flights from Islip to Knoxville that include hotel bookings?
Yes. In addition to deals on Islip to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Islip to Knoxville?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Islip to Knoxville.
Can I find deals for business class flights from Islip to Knoxville?
Yes. Cheapflights offers flight deals from Islip to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Islip, New York to Knoxville?
Currently, January is the cheapest month in which you can book a flight from Islip, New York to Knoxville (average of $296). Flying from Islip, New York to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Morristown

Cherokee

Corbin

Maryville

Oak Ridge

Alcoa

Murphy

Browse thousands of different options on Cheapflights for your next trip

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$296+ Cheap flights from Islip, NY to Knoxville (ISP - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/16. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Islip to Knoxville with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Islip to Knoxville

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Islip to Knoxville

Cheapest flights from Islip to KnoxvilleExplore the most affordable flight options available from Islip to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

Explore the most affordable flight options available from Islip to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Islip to Knoxville that are best for you.

Best time to book a flight from Islip to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Islip with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Islip to Knoxville

What is the cheapest month to book a flight from Islip, New York to Knoxville?

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

Reviews of airlines servicing Knoxville

Related info for your journey

Find useful and relevant information for your journey from Islip to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

Can I find deals for flights from Islip to Knoxville that include hotel bookings?

How can I find direct flights from Islip to Knoxville?

Can I find deals for business class flights from Islip to Knoxville?

What is the cheapest month to book a flight from Islip, New York to Knoxville?

Traveling to a place near Islip?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Islip to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Islip to Knoxville
Explore the most affordable flight options available from Islip to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.