What are the cheapest airlines flying from Detroit to Knoxville round-trip?

Frontier, at $234, was found to be the cheapest airline from Detroit to Knoxville. An alternate airline flying to your destination would be American Airlines. Frontier is currently priced 45% below the average price you’ll pay for this route.

What are the cheapest airlines to fly from Detroit to Knoxville one-way?

One-way options have recently been found by users for as low as $175 on Frontier. Other airlines that offer cheap prices include Delta from $249 and American Airlines from $259 one-way.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

What are the cheapest flights from Detroit to Knoxville?

The cheapest flight price from Detroit to Knoxville is $248. On average you can expect to pay $399. The most popular route, (Detroit Metropolitan Wayne County - Knoxville McGhee Tyson), can usually be booked for $204.

What are the most reliable airlines from Detroit to Knoxville?

Before booking your flight to Knoxville from Detroit, check out the most reliable airlines to get you to your destination on time: WestJet (83%), Air France (81%), Delta( 75%).

What is the cheapest day to fly round-trip from Detroit to Knoxville?

Saturday flights are found to be more expensive to fly from Detroit to Knoxville. This shouldn’t discourage you from searching, as you can still find great deals by being flexible with your options. Use our search form to find deals on tickets to Knoxville.

How far in advance should I book a flight from Detroit to Knoxville?

To save on the cost of your flight from Detroit to Knoxville, book at least 22 days before your planned departure. Booking around this time can save you about 30% on the cost of this flight compared to booking a flight leaving this week. We have found prices from $374 if you need a flight within two weeks. For flights within the next 72 hours, you can find tickets from as low as $374.

What is the cheapest month to fly from Detroit to Knoxville?

The best pricing can be found in the month of April. Prices to Knoxville from Detroit average $431. You can even find prices in April for less than $431, as users have found deals to Knoxville from as low as $299. The month of June appears to be one of the more expensive times to travel to Knoxville from Detroit. Flying in the targeted month can save you up to 31%.

What airports do I use to fly from Detroit to Knoxville?

Knoxville McGhee Tyson is the airport most travelers will use when flying to Knoxville from Detroit All airports. Booking flights from All airports (DTT) to McGhee Tyson (TYS) should be relatively easy as there are 5 daily flights to Knoxville from 2 different airlines. 1h 31m is how long a flight from Detroit to Knoxville McGhee Tyson will take if you book a nonstop flight.

Can I find deals for flights from Detroit to Knoxville that include hotel bookings?

Yes. In addition to deals on Detroit to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Detroit to Knoxville?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Knoxville.

Can I find deals for business class flights from Detroit to Knoxville?

Yes. Cheapflights offers flight deals from Detroit to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$85+ Flights from Detroit to Knoxville

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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

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Cheapflights Tip: The best prices from Detroit All airports to Knoxville McGhee Tyson are usually found in April or July, booked 21 days in advance, depart on a Saturday or Wednesday and return on a Thursday

Cheap flight deals from Detroit to Knoxville

Round-trip from	$186 (Mytrip)
One-way from	$85 (Mytrip)
Popular in	June
Cheapest in	April
Average price	$399
Good round-trip deal	$459 or less
Good one-way deal	$248 or less

From Detroit (DTT) to Knoxville McGhee Tyson

Search Deals

One-way flight from Detroit (DTT) to Knoxville McGhee Tyson

Search Deals

Highest demand for flights based on searches. 5% potential increase in price ($27 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 3% potential price decrease ($13 potential savings vs. average RT price).

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Average for round-trip flights in July 2025

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Price to beat on a round-trip flight from Detroit (DTT) to Knoxville McGhee Tyson.

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Price to beat on a one-way flight from Detroit (DTT) to Knoxville McGhee Tyson.

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Find flight deals from Detroit to Knoxville

Cheapest flights from Detroit to Knoxville
Explore the most affordable flight options available from Detroit to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

Thu 8/78:38 amDTW - TYS

1 stop11h 26mMultiple Airlines

Sun 8/108:54 pmTYS - DTW

1 stop13h 29mMultiple Airlines

Deal found 7/3

$178

Thu 8/2111:54 amDTW - TYS

1 stop7h 47mFrontier

Mon 8/257:10 pmTYS - DTW

1 stop26h 33mFrontier

Deal found 6/30

$234

Wed 10/225:30 amDTW - TYS

1 stop9h 03mAmerican Airlines

Sat 10/253:03 pmTYS - DTW

1 stop8h 21mAmerican Airlines

Deal found 7/1

$269

Best flights from Detroit to Knoxville
Discover carefully curated flight deals from Detroit to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 3, 2025.

Mon 8/46:10 amDTW - TYS

1 stop10h 37mMultiple Airlines

Fri 8/86:55 amTYS - DTW

1 stop10h 48mMultiple Airlines

Deal found 6/30

$186

Thu 8/2111:54 amDTW - TYS

1 stop7h 47mFrontier

Mon 8/257:10 pmTYS - DTW

1 stop26h 33mFrontier

Deal found 6/30

$234

Wed 10/225:30 amDTW - TYS

1 stop9h 03mAmerican Airlines

Sat 10/253:03 pmTYS - DTW

1 stop8h 21mAmerican Airlines

Deal found 7/1

$269

Last-minute flights from Detroit to Knoxville
Discover last-minute flight deals from Detroit to Knoxville. Data last updated July 3, 2025 and is based on user searches.

Thu 7/106:00 amDTW - TYS

1 stop10h 29mFrontier

Sun 7/135:25 pmTYS - DTW

1 stop7h 17mFrontier

Deal found 7/3

$375

Fri 7/1110:15 amDTW - TYS

1 stop5h 57mMultiple Airlines

Mon 7/1411:01 amTYS - DTW

1 stop5h 10mMultiple Airlines

Deal found 7/1

$259

Fri 7/117:45 pmDTW - TYS

Nonstop1h 31mDelta

Tue 7/157:50 amTYS - DTW

Nonstop1h 40mDelta

Deal found 7/3

$559

Sat 7/129:19 amDTW - TYS

1 stop8h 20mAmerican Airlines

Sat 7/197:29 amTYS - DTW

1 stop9h 21mAmerican Airlines

Deal found 7/3

$462

Sat 7/129:40 amDTW - TYS

2 stops11h 17mUnited Airlines

Sat 7/195:45 amTYS - DTW

1 stop4h 28mUnited Airlines

Deal found 7/3

$544

Thu 8/78:38 amDTW - TYS

1 stop11h 26mMultiple Airlines

Sun 8/108:54 pmTYS - DTW

1 stop13h 29mMultiple Airlines

Deal found 7/3

$178

Thu 8/2111:54 amDTW - TYS

1 stop7h 47mFrontier

Mon 8/257:10 pmTYS - DTW

1 stop26h 33mFrontier

Deal found 6/30

$234

One-way flights from Detroit to Knoxville
Search for one-way flight options from Detroit to Knoxville. Find affordable one-way fares based on user searches. Data last updated July 3, 2025.

Fri 7/186:10 amDTW - TYS

1 stop10h 37mMultiple Airlines

Deal found 7/1

$85

Sun 7/66:00 amDTW - TYS

1 stop10h 29mFrontier

Deal found 7/1

$175

Tue 8/127:45 pmDTW - TYS

Nonstop1h 32mDelta

Deal found 7/2

$249

Tue 8/129:55 amDTW - TYS

1 stop7h 02mAmerican Airlines

Deal found 7/2

$259

Thu 7/247:14 amDTW - TYS

2 stops7h 44mUnited Airlines

Deal found 7/3

$467

Cheapflights Fare Finder

Use the filters below to find and compare flights from Detroit to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Thu 8/7

8:38 am-8:04 pm

1 stop11h 26m

Knoxville McGhee Tyson

Sun 8/10

8:54 pm-10:23 am

1 stop13h 29m

$178

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Thu 8/21

11:54 am-7:41 pm

1 stop7h 47m

Knoxville McGhee Tyson

Mon 8/25

7:10 pm-9:43 pm

1 stop26h 33m

$234

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Fri 7/18

6:10 am-4:47 pm

1 stop10h 37m

$85

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Sun 7/6

6:00 am-4:29 pm

1 stop10h 29m

$175

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Tue 8/12

7:45 pm-9:17 pm

Nonstop1h 32m

$249

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Tue 8/12

9:55 am-4:57 pm

1 stop7h 02m

$259

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Thu 7/24

7:14 am-2:58 pm

2 stops7h 44m

$467

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Best time to book a flight from Detroit to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Detroit with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit to Knoxville

How far ahead should I book a flight from Detroit to Knoxville?

To ensure you get the cheapest price possible for a flight from Detroit to Knoxville, you should look to book at least 21 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Detroit to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Detroit to Knoxville (average of $296). Flying from Detroit to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTT to TYS?

When flying from Detroit to Knoxville, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 12% versus a flight in the afternoon.

What is the cheapest day to fly from Detroit to Knoxville?

Travelers seeking maximum savings on their Detroit to Knoxville flight should consider departing on Monday at noon when fares are most often at their lowest. Friday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Detroit to Knoxville?

Reviews of airlines servicing Knoxville

Read through reviews of airlines operating flights from Detroit to Knoxville, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,982 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,982 reviews

Delta

8.0

Very good

7,982 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

United Airlines

7.4

Good

8,861 reviews

Delta

8.0

Very good

7,982 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,982 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Frontier

5.9

Fair

3,286 reviews

Delta

8.0

Very good

7,982 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What airports do I use to fly from Detroit to Knoxville?
Knoxville McGhee Tyson is the airport most travelers will use when flying to Knoxville from Detroit All airports. Booking flights from All airports (DTT) to McGhee Tyson (TYS) should be relatively easy as there are 5 daily flights to Knoxville from 2 different airlines. 1h 31m is how long a flight from Detroit to Knoxville McGhee Tyson will take if you book a nonstop flight.
What are the cheapest airlines flying from Detroit to Knoxville round-trip?
Frontier, at $234, was found to be the cheapest airline from Detroit to Knoxville. An alternate airline flying to your destination would be American Airlines. Frontier is currently priced 45% below the average price you’ll pay for this route.
What are the cheapest airlines to fly from Detroit to Knoxville one-way?
One-way options have recently been found by users for as low as $175 on Frontier. Other airlines that offer cheap prices include Delta from $249 and American Airlines from $259 one-way.
What are the most reliable airlines from Detroit to Knoxville?
Before booking your flight to Knoxville from Detroit, check out the most reliable airlines to get you to your destination on time: WestJet (83%), Air France (81%), Delta( 75%).
What are the cheapest flights from Detroit to Knoxville?
The cheapest flight price from Detroit to Knoxville is $248. On average you can expect to pay $399. The most popular route, (Detroit Metropolitan Wayne County - Knoxville McGhee Tyson), can usually be booked for $204.
Can I find deals for flights from Detroit to Knoxville that include hotel bookings?
Yes. In addition to deals on Detroit to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Detroit to Knoxville?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Knoxville.
Can I find deals for business class flights from Detroit to Knoxville?
Yes. Cheapflights offers flight deals from Detroit to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Detroit to Knoxville?
Currently, January is the cheapest month in which you can book a flight from Detroit to Knoxville (average of $296). Flying from Detroit to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Cherokee

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Oak Ridge

Murphy

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Complete your trip

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Other flights to Knoxville

Top 2 airlines flying from Detroit to Knoxville

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$259	Average$378	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$309	Average$461	FlexibilityNo cancel fee	On-timeN/A

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$85+ Cheap flights from Detroit to Knoxville (DTT - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/18. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Detroit to Knoxville with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Detroit All airports to Knoxville McGhee Tyson are usually found in April or July, booked 21 days in advance, depart on a Saturday or Wednesday and return on a Thursday

Cheap flight deals from Detroit to Knoxville

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Find flight deals from Detroit to Knoxville

Cheapest flights from Detroit to KnoxvilleExplore the most affordable flight options available from Detroit to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

Explore the most affordable flight options available from Detroit to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Detroit to Knoxville that are best for you.

Best time to book a flight from Detroit to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Detroit with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Detroit to Knoxville

How far ahead should I book a flight from Detroit to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from Detroit to Knoxville. Price data was last updated on June 27, 2025.

What is the cheapest month to book a flight from Detroit to Knoxville?

What is the cheapest time of day to fly from DTT to TYS?

Find hourly flight availability from Detroit to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 3, 2025.

What is the cheapest day to fly from Detroit to Knoxville?

Use this chart to determine the cheapest time to fly round-trip from Detroit to Knoxville. Price data was last updated on June 29, 2025.

How much does it cost to fly round-trip from Detroit to Knoxville?

Reviews of airlines servicing Knoxville

Read through reviews of airlines operating flights from Detroit to Knoxville, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Detroit to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airports do I use to fly from Detroit to Knoxville?

What are the cheapest airlines flying from Detroit to Knoxville round-trip?

What are the cheapest airlines to fly from Detroit to Knoxville one-way?

What are the most reliable airlines from Detroit to Knoxville?

What are the cheapest flights from Detroit to Knoxville?

Can I find deals for flights from Detroit to Knoxville that include hotel bookings?

How can I find direct flights from Detroit to Knoxville?

Can I find deals for business class flights from Detroit to Knoxville?

What is the cheapest month to book a flight from Detroit to Knoxville?

Traveling to a place near Detroit?

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Alternative routes for Detroit to Knoxville

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Top 2 airlines flying from Detroit to Knoxville

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Cheapest flights from Detroit to Knoxville
Explore the most affordable flight options available from Detroit to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.