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$110+ Cheap flights from Detroit to Knoxville (DTT - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/14. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — TYS
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Detroit to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTT) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2025.

Round-trip from

$188
(Priceline)

One-way from

$110
(Kiwi.com)

Popular in

June

Cheapest in

April

Average price

$538

Good round-trip deal

$359 or less
From Detroit (DTT) to Knoxville McGhee Tyson
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One-way flight from Detroit (DTT) to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 4% potential increase in price ($18 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Detroit (DTT) to Knoxville McGhee Tyson.
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Find flight deals from Detroit to Knoxville

Cheapest flights from Detroit to Knoxville
Explore the most affordable flight options available from Detroit to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Priceline deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/216:10 amDTW - TYS
1 stop10h 08mFrontier
Sun 9/285:08 pmTYS - DTW
1 stop7h 38mFrontier
Deal found 9/14$188
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/34:55 pmDTW - TYS
1 stop20h 06mMultiple Airlines
Fri 11/76:12 pmTYS - DTW
1 stop14h 10mMultiple Airlines
Deal found 9/14$209
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/269:11 pmDTW - TYS
1 stop12h 12mMultiple Airlines
Sat 9/279:05 pmTYS - DTW
1 stop11h 39mMultiple Airlines
Deal found 9/12$234
This Priceline deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2511:54 amDTW - TYS
1 stop7h 56mFrontier
Sun 9/285:08 pmTYS - DTW
1 stop7h 38mFrontier
Deal found 9/14$240
This Priceline deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/211:54 amDTW - TYS
1 stop7h 56mFrontier
Sun 10/55:08 pmTYS - DTW
1 stop7h 38mFrontier
Deal found 9/15$247
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/148:20 pmDTW - TYS
1 stop15h 35mMultiple Airlines
Tue 10/218:00 amTYS - DTW
1 stop24h 20mMultiple Airlines
Deal found 9/14$254
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/137:05 amDTW - TYS
1 stop13h 31mMultiple Airlines
Mon 10/207:02 pmTYS - DTW
1 stop20h 18mMultiple Airlines
Deal found 9/15$259
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/69:20 pmDTW - TYS
2 stops25h 06mMultiple Airlines
Mon 11/107:20 amTYS - DTW
1 stop9h 58mMultiple Airlines
Deal found 9/14$260
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/216:10 amDTW - TYS
1 stop10h 08mMultiple Airlines
Thu 9/257:00 amTYS - DTW
1 stop17h 46mMultiple Airlines
Deal found 9/13$263

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Detroit to Knoxville that are best for you.

Fly from

Detroit

Fly to

Knoxville

Route

Depart

Return

Price

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Mon 11/3

7:28 am-6:27 pm

2 stops10h 59m

Knoxville McGhee Tyson

Fri 11/7

6:12 pm-8:22 am

1 stop14h 10m

$253

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Thu 11/6

8:00 am-10:33 pm

2 stops14h 33m

Knoxville McGhee Tyson

Sun 11/9

8:30 am-8:11 am

1 stop23h 41m

$269

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Wed 11/12

6:45 am-2:34 pm

1 stop7h 49m

Knoxville McGhee Tyson

Sat 11/15

7:54 am-6:28 pm

1 stop10h 34m

$275

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Sat 12/13

6:20 pm-8:00 pm

Nonstop1h 40m

Knoxville McGhee Tyson

Tue 12/16

7:39 am-9:29 am

Nonstop1h 50m

$299

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Sat 11/8

7:35 pm-9:13 pm

Nonstop1h 38m

Knoxville McGhee Tyson

Tue 11/11

7:39 am-9:30 am

Nonstop1h 51m

$299

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Sat 11/22

6:20 pm-8:00 pm

Nonstop1h 40m

Knoxville McGhee Tyson

Thu 11/27

7:39 am-9:30 am

Nonstop1h 51m

$299

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Wed 11/12

10:05 am-11:45 am

Nonstop1h 40m

Knoxville McGhee Tyson

Sat 11/15

7:39 am-9:30 am

Nonstop1h 51m

$299

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Tue 10/14

7:35 pm-9:13 pm

Nonstop1h 38m

Knoxville McGhee Tyson

Tue 10/21

12:47 pm-2:30 pm

Nonstop1h 43m

$299

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Wed 11/26

6:20 pm-8:00 pm

Nonstop1h 40m

Knoxville McGhee Tyson

Tue 12/2

5:25 pm-10:29 pm

1 stop5h 04m

$309

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Sat 11/8

9:30 pm-2:05 pm

1 stop16h 35m

$116

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Showing 1-10 of 18 results
1
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Best time to book a flight from Detroit to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit to Knoxville

What is the cheapest month to book a flight from Detroit to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Detroit to Knoxville (average of $295). Flying from Detroit to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTT to TYS?

Find hourly flight availability from Detroit to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

When flying from Detroit to Knoxville, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 12% versus a flight in the afternoon.

What is the cheapest day to fly from Detroit to Knoxville?

Use this chart to determine the cheapest time to fly round-trip from Detroit to Knoxville. Price data was last updated on September 14, 2025.

Travelers seeking maximum savings on their Detroit to Knoxville flight should consider departing on Monday at noon when fares are most often at their lowest. Friday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Detroit to Knoxville

Explore weekly flight availability from Detroit to Knoxville. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 15, 2025.

The most flights from DTT to TYS are scheduled on a Monday (9 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (7 on average).

How much does it cost to fly round-trip from Detroit to Knoxville?

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated September 15, 2025.
Read through reviews of airlines operating flights from Detroit to Knoxville, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,954 reviews

Comfort

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,954 reviews
Delta
8.0
Very good
7,954 reviews

Comfort

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,954 reviews

Comfort

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Detroit to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Detroit to Knoxville?

    Knoxville McGhee Tyson is the airport most travelers will use when flying to Knoxville from Detroit All airports. Booking flights from All airports (DTT) to McGhee Tyson (TYS) should be relatively easy as there are 8 daily flights to Knoxville from 2 different airlines. 1h 34m is how long a flight from Detroit to Knoxville McGhee Tyson will take if you book a nonstop flight.

  • How long is the flight from Detroit to Knoxville?

    For as low as $299, American Airlines can have you in Knoxville from Detroit in 1h 40m. The distance between Detroit and Knoxville is about 444 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Detroit to Knoxville round-trip?

    American Airlines, at $216, was found to be the cheapest airline from Detroit to Knoxville. An alternate airline flying to your destination would be Delta. American Airlines is currently priced 50% below the average price you’ll pay for this route.

  • What are the most reliable airlines from Detroit to Knoxville?

    Before booking your flight to Knoxville from Detroit, check out the most reliable airlines to get you to your destination on time: Delta (72%), Endeavor Airlines (72%), WestJet( 66%).

  • What are the cheapest flights from Detroit to Knoxville?

    The cheapest flight price from Detroit to Knoxville is $299. On average you can expect to pay $479. The most popular route, (Detroit Metropolitan Wayne County - Knoxville McGhee Tyson), can usually be booked for $209.

  • Can I find deals for flights from Detroit to Knoxville that include hotel bookings?

    Yes. In addition to deals on Detroit to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Knoxville.

  • Can I find deals for business class flights from Detroit to Knoxville?

    Yes. Cheapflights offers flight deals from Detroit to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Detroit to Knoxville (average of $295). Flying from Detroit to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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Top 2 airlines flying from Detroit to Knoxville

Discover the top 2 airlines that operate flights from Detroit to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$216Average$398FlexibilityNo cancel feeOn-time71%
DeltaCheapest$309Average$452FlexibilityNo cancel feeOn-timeN/A

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