$121+ Cheap flights from Detroit to Knoxville (DTT - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/12. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — TYS
Jun 25 — Jul 21
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Detroit to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Detroit to Knoxville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Detroit to KnoxvilleExplore the most affordable flight options available from Detroit to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 26, 2026.
Explore the most affordable flight options available from Detroit to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 26, 2026.
This Booking.com deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/127:40 am
DTW
- TYS
1 stop11h 44m
Frontier
Wed 8/198:32 pm
TYS
- DTW
1 stop16h 05m
Frontier
Deal found 5/21![Frontier logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1911:00 am
DTW
- TYS
1 stop23h 04m
Multiple Airlines
Mon 8/246:54 pm
TYS
- DTW
1 stop18h 13m
Multiple Airlines
Deal found 5/25![Multiple Airlines logo]()
$280
This Kiwi.com deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/319:12 am
DTW
- TYS
1 stop9h 18m
Multiple Airlines
Mon 8/312:40 pm
TYS
- DTW
2 stops24h 53m
Multiple Airlines
Deal found 5/21![Multiple Airlines logo]()
$283
This Kiwi.com deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/99:12 am
DTW
- TYS
1 stop23h 24m
Multiple Airlines
Fri 8/149:26 am
TYS
- DTW
1 stop27h 29m
Multiple Airlines
Deal found 5/25![Multiple Airlines logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/99:12 am
DTW
- TYS
1 stop23h 24m
Multiple Airlines
Wed 8/1212:56 pm
TYS
- DTW
1 stop23h 59m
Multiple Airlines
Deal found 5/25![Multiple Airlines logo]()
$294
This Kiwi.com deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/119:12 am
DTW
- TYS
1 stop26h 54m
Multiple Airlines
Sun 8/168:29 pm
TYS
- DTW
1 stop16h 26m
Multiple Airlines
Deal found 5/25![Multiple Airlines logo]()
$297
This Southwest deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:00 am
DTW
- TYS
1 stop6h 05m
Southwest
Tue 8/185:30 pm
TYS
- DTW
1 stop4h 00m
Southwest
Deal found 5/25![Southwest logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/119:12 am
DTW
- TYS
1 stop26h 54m
Multiple Airlines
Sat 8/155:03 pm
TYS
- DTW
1 stop19h 52m
Multiple Airlines
Deal found 5/25![Multiple Airlines logo]()
$301
This Booking.com deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/47:45 am
DTW
- TYS
1 stop11h 52m
Frontier
Mon 9/78:32 pm
TYS
- DTW
1 stop27h 27m
Frontier
Deal found 5/25![Frontier logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/99:12 am
DTW
- TYS
1 stop23h 24m
Multiple Airlines
Thu 8/138:29 pm
TYS
- DTW
1 stop16h 26m
Multiple Airlines
Deal found 5/25![Multiple Airlines logo]()
$306
This Kiwi.com deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/197:51 pm
DTW
- TYS
1 stop27h 42m
Multiple Airlines
Thu 7/309:11 pm
TYS
- DTW
1 stop15h 44m
Multiple Airlines
Deal found 5/25![Multiple Airlines logo]()
$309
Best flights from Detroit to KnoxvilleDiscover carefully curated flight deals from Detroit to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 26, 2026.
Discover carefully curated flight deals from Detroit to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 26, 2026.
This Southwest deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:25 am
DTW
- TYS
2 stops7h 55m
Southwest
Tue 8/1812:45 pm
TYS
- DTW
2 stops8h 45m
Southwest
Deal found 5/25![Southwest logo]()
$309
This Delta deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:59 pm
DTW
- TYS
Nonstop1h 39m
Delta
Wed 7/153:59 pm
TYS
- DTW
Nonstop1h 44m
Delta
Deal found 5/23![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/77:55 pm
DTW
- TYS
Nonstop1h 39m
Delta
Wed 8/127:11 am
TYS
- DTW
Nonstop1h 46m
Delta
Deal found 5/25![Delta logo]()
$339
This Southwest deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/233:50 pm
DTW
- TYS
1 stop5h 25m
Southwest
Thu 6/257:45 pm
TYS
- DTW
1 stop4h 20m
Southwest
Deal found 5/21![Southwest logo]()
$357
This Delta deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/48:25 am
DTW
- TYS
Nonstop1h 46m
Delta
Wed 7/811:41 am
TYS
- DTW
Nonstop1h 44m
Delta
Deal found 5/24![Delta logo]()
$339
This Southwest deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2411:10 am
DTW
- TYS
2 stops8h 45m
Southwest
Sun 8/301:15 pm
TYS
- DTW
2 stops9h 45m
Southwest
Deal found 5/25![Southwest logo]()
$359
This Delta deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/29:25 am
DTW
- TYS
1 stop5h 24m
Delta
Mon 7/67:15 am
TYS
- DTW
Nonstop1h 49m
Delta
Deal found 5/24![Delta logo]()
$349
This Delta deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/249:25 am
DTW
- TYS
1 stop4h 09m
Delta
Sun 8/307:11 am
TYS
- DTW
Nonstop1h 46m
Delta
Deal found 5/25![Delta logo]()
$349
This Southwest deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/221:25 pm
DTW
- TYS
2 stops9h 05m
Southwest
Tue 6/3012:45 pm
TYS
- DTW
2 stops9h 40m
Southwest
Deal found 5/22![Southwest logo]()
$407
This Delta deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:17 am
DTW
- TYS
1 stop4h 53m
Delta
Mon 7/2011:41 am
TYS
- DTW
Nonstop1h 44m
Delta
Deal found 5/25![Delta logo]()
$349
This Delta deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/77:40 pm
DTW
- TYS
1 stop4h 12m
Delta
Tue 8/115:45 am
TYS
- DTW
1 stop4h 25m
Delta
Deal found 5/25![Delta logo]()
$359
This Delta deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/207:59 pm
DTW
- TYS
Nonstop1h 42m
Delta
Wed 6/247:15 am
TYS
- DTW
Nonstop1h 49m
Delta
Deal found 5/24![Delta logo]()
$369
Last-minute flights from Detroit to KnoxvilleDiscover last-minute flight deals from Detroit to Knoxville. Data last updated May 26, 2026 and is based on user searches.
Discover last-minute flight deals from Detroit to Knoxville. Data last updated May 26, 2026 and is based on user searches.
This Booking.com deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:55 am
DTW
- TYS
1 stop11h 38m
Frontier
Mon 6/88:32 pm
TYS
- DTW
1 stop16h 14m
Frontier
Deal found 5/25![Frontier logo]()
$353
This Booking.com deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/87:55 am
DTW
- TYS
1 stop11h 38m
Frontier
Wed 6/108:32 pm
TYS
- DTW
1 stop27h 27m
Frontier
Deal found 5/25![Frontier logo]()
$302
This Booking.com deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/128:00 am
DTW
- TYS
1 stop11h 37m
Frontier
Mon 6/158:32 pm
TYS
- DTW
1 stop16h 14m
Frontier
Deal found 5/21![Frontier logo]()
$352
This Southwest deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:40 am
DTW
- TYS
2 stops10h 20m
Southwest
Wed 6/246:55 pm
TYS
- DTW
1 stop3h 30m
Southwest
Deal found 5/21![Southwest logo]()
$343
This Booking.com deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/228:00 am
DTW
- TYS
1 stop11h 37m
Frontier
Fri 6/268:32 pm
TYS
- DTW
1 stop27h 27m
Frontier
Deal found 5/24![Frontier logo]()
$332
This Southwest deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/236:40 am
DTW
- TYS
2 stops10h 20m
Southwest
Thu 6/257:45 pm
TYS
- DTW
1 stop4h 20m
Southwest
Deal found 5/21![Southwest logo]()
$348
This Booking.com deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/248:00 am
DTW
- TYS
1 stop11h 37m
Frontier
Wed 7/18:32 pm
TYS
- DTW
1 stop27h 27m
Frontier
Deal found 5/25![Frontier logo]()
$323
This Delta deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/268:40 am
DTW
- TYS
Nonstop1h 47m
Delta
Tue 6/307:15 am
TYS
- DTW
Nonstop1h 49m
Delta
Deal found 5/21![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/267:58 pm
DTW
- TYS
1 stop3h 49m
American Airlines
Mon 6/297:59 pm
TYS
- DTW
1 stop4h 34m
American Airlines
Deal found 5/24![American Airlines logo]()
$359
This Kiwi.com deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/298:00 am
DTW
- TYS
2 stops15h 34m
Multiple Airlines
Thu 7/97:15 am
TYS
- DTW
1 stop29h 40m
Multiple Airlines
Deal found 5/22![Multiple Airlines logo]()
$344
One-way flights from Detroit to KnoxvilleSearch for one-way flight options from Detroit to Knoxville. Find affordable one-way fares based on user searches. Data last updated May 26, 2026.
Search for one-way flight options from Detroit to Knoxville. Find affordable one-way fares based on user searches. Data last updated May 26, 2026.
This Frontier deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/127:40 am
DTW
- TYS
1 stop11h 44m
Frontier
Deal found 5/24![Frontier logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/229:12 am
DTW
- TYS
1 stop8h 47m
Multiple Airlines
Deal found 5/23![Multiple Airlines logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1811:00 am
DTW
- TYS
1 stop23h 04m
Multiple Airlines
Deal found 5/24![Multiple Airlines logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2011:00 am
DTW
- TYS
1 stop31h 04m
Multiple Airlines
Deal found 5/24![Multiple Airlines logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/209:12 am
DTW
- TYS
1 stop30h 58m
Multiple Airlines
Deal found 5/25![Multiple Airlines logo]()
$134
This Frontier deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/177:40 am
DTW
- TYS
1 stop11h 44m
Frontier
Deal found 5/24![Frontier logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1911:00 am
DTW
- TYS
1 stop29h 02m
Multiple Airlines
Deal found 5/26![Multiple Airlines logo]()
$136
This Kiwi.com deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/159:12 am
DTW
- TYS
1 stop8h 47m
Multiple Airlines
Deal found 5/22![Multiple Airlines logo]()
$138
This Frontier deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/207:40 am
DTW
- TYS
1 stop11h 44m
Frontier
Deal found 5/24![Frontier logo]()
$140
This Frontier deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/217:45 am
DTW
- TYS
1 stop11h 52m
Frontier
Deal found 5/24![Frontier logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/219:12 am
DTW
- TYS
1 stop6h 58m
Multiple Airlines
Deal found 5/23![Multiple Airlines logo]()
$144
This Southwest deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1812:55 pm
DTW
- TYS
2 stops6h 00m
Southwest
Deal found 5/22![Southwest logo]()
$145
Find flight deals from Detroit to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTT) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $242 (Booking.com) |
One-way from | $121 (Frontier) |
Popular in | June |
Cheapest in | May |
Average price | $355 |
Good round-trip deal | $399 or less |
Good one-way deal | $248 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 26, 2026.
Use the filters below to find and compare flights from Detroit to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitKnoxville
DTW - TYS
DTWTYS
Detroit Metropolitan Wayne County
Tue 8/4
6:25 am-2:20 pm
2 stops7h 55m
Knoxville McGhee Tyson
Tue 8/18
12:45 pm-9:30 pm
2 stops8h 45m
$309
Quickest round-trip
DetroitKnoxville
DTW - TYS
DTWTYS
Detroit Metropolitan Wayne County
Thu 7/9
7:59 pm-9:38 pm
Nonstop1h 39m
Knoxville McGhee Tyson
Wed 7/15
3:59 pm-5:43 pm
Nonstop1h 44m
$339
DetroitKnoxville
DTW - TYS
DTWTYS
Detroit Metropolitan Wayne County
Fri 8/7
7:55 pm-9:34 pm
Nonstop1h 39m
Knoxville McGhee Tyson
Wed 8/12
7:11 am-8:57 am
Nonstop1h 46m
$339
DetroitKnoxville
DTW - TYS
DTWTYS
Detroit Metropolitan Wayne County
Sat 7/4
8:25 am-10:11 am
Nonstop1h 46m
Knoxville McGhee Tyson
Wed 7/8
11:41 am-1:25 pm
Nonstop1h 44m
$339
DetroitKnoxville
DTW - TYS
DTWTYS
Detroit Metropolitan Wayne County
Thu 7/2
9:25 am-2:49 pm
1 stop5h 24m
Knoxville McGhee Tyson
Mon 7/6
7:15 am-9:04 am
Nonstop1h 49m
$349
DetroitKnoxville
DTW - TYS
DTWTYS
Detroit Metropolitan Wayne County
Mon 8/24
9:25 am-1:34 pm
1 stop4h 09m
Knoxville McGhee Tyson
Sun 8/30
7:11 am-8:57 am
Nonstop1h 46m
$349
DetroitKnoxville
DTW - TYS
DTWTYS
Detroit Metropolitan Wayne County
Wed 7/15
6:17 am-11:10 am
1 stop4h 53m
Knoxville McGhee Tyson
Mon 7/20
11:41 am-1:25 pm
Nonstop1h 44m
$349
DetroitKnoxville
DTW - TYS
DTWTYS
Detroit Metropolitan Wayne County
Tue 6/23
3:50 pm-9:15 pm
1 stop5h 25m
Knoxville McGhee Tyson
Thu 6/25
7:45 pm-12:05 am
1 stop4h 20m
$357
DetroitKnoxville
DTW - TYS
DTWTYS
Detroit Metropolitan Wayne County
Mon 8/24
11:10 am-7:55 pm
2 stops8h 45m
Knoxville McGhee Tyson
Sun 8/30
1:15 pm-11:00 pm
2 stops9h 45m
$359
DetroitKnoxville
DTW - TYS
DTWTYS
Detroit Metropolitan Wayne County
Fri 8/7
7:40 pm-11:52 pm
1 stop4h 12m
Knoxville McGhee Tyson
Tue 8/11
5:45 am-10:10 am
1 stop4h 25m
$359
Showing 1-10 of 22 resultsSorted by cheapest first
Compare providers for flights from Detroit to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Knoxville in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Detroit-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Detroit-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Detroit to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Detroit with our price prediction graph.
DTT-TYS
DTW-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Detroit to Knoxville
DTT-TYS
DTW-TYS
What is the cheapest month to book a flight from Detroit to Knoxville?
Currently, October is the cheapest month in which you can book a flight from Detroit to Knoxville (average of $218). Flying from Detroit to Knoxville in June is currently the most expensive (average of $339). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DTT to TYS?
Find hourly flight availability from Detroit to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 26, 2026.
When flying from Detroit to Knoxville, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 31% versus a flight at noon.
Weekly flight availability from Detroit to Knoxville
Explore weekly flight availability from Detroit to Knoxville. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated May 26, 2026.
The most flights from DTT to TYS are scheduled on a Monday (15 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (5 on average).
How much does it cost to fly round-trip from Detroit to Knoxville?
How far ahead should I book a flight from Detroit to Knoxville?
To ensure you get the cheapest price possible for a flight from Detroit to Knoxville, you should look to book at least 20 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated May 26, 2026.
Read through reviews of airlines operating flights from Detroit to Knoxville, such as Delta. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Entertainment
7.8
Food
7.2
Overall
7.9
Comfort
7.8
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Entertainment
7.8
Food
7.2
Overall
7.9
Comfort
7.8
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Detroit to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa
Oak Ridge
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Knoxville flight routes
Other flight options
Other flights from Detroit
Popular flights
Alternative routes for Detroit to Knoxville
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Knoxville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Detroit to Knoxville by cabin class
Find flights from Detroit to Knoxville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 26, 2026.
Detroit and Knoxville flights
Browse other Detroit and Knoxville flight options. Last updated on May 26, 2026.
Other flights from Detroit
Browse through other flights departing from Detroit. Flights are based on user searches made on Cheapflights and were last updated on May 26, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Detroit to Knoxville
Discover the top airline that operate flights from Detroit to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$299 | Average$424 | FlexibilityNo cancel fee | On-timeN/A |