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$219+ Cheap flights from San Antonio to Key West (SAT - EYW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/12. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — EYW
Dec 4 — Dec 111
Thu 12/4
Thu 12/11
1 adult, Economy
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Cheap flight deals from San Antonio to Key West

Discover tips and strategies to find the most affordable flight options for your journey from San Antonio (SAT) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$225
(American Airlines)

One-way from

$219
(Mytrip)

Popular in

June

Cheapest in

August

Average price

$422
Provider with most accurate pricing for San Antonio-Key West flight deals.
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Provider most trusted by Cheapflights users for San Antonio-Key West flights.
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From San Antonio to Key West
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One-way flight from San Antonio to Key West
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Highest demand for flights based on searches. 11% potential increase in price ($58 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($18 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from San Antonio to Key West

Cheapest flights from San Antonio to Key West
Explore the most affordable flight options available from San Antonio to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2025.

This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/411:53 amSAT - EYW
1 stop8h 52mAmerican Airlines
Wed 12/106:33 pmEYW - SAT
1 stop6h 52mAmerican Airlines
Deal found 11/2$225
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1711:36 amSAT - EYW
1 stop7h 30mDelta
Mon 12/227:25 amEYW - SAT
1 stop6h 03mDelta
Deal found 11/3$228
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/237:39 pmSAT - EYW
1 stop11h 36mMultiple Airlines
Thu 11/2712:15 pmEYW - SAT
1 stop7h 17mMultiple Airlines
Deal found 11/3$271
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/136:00 amSAT - EYW
2 stops9h 12mAmerican Airlines
Fri 12/194:03 pmEYW - SAT
1 stop8h 23mAmerican Airlines
Deal found 11/3$276
This Mytrip deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/137:00 amSAT - EYW
3 stops27h 20mSpirit Airlines
Fri 12/192:30 pmEYW - SAT
1 stop9h 56mSpirit Airlines
Deal found 11/3$292
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/188:00 amSAT - EYW
1 stop5h 03mDelta
Sat 11/226:18 pmEYW - SAT
1 stop6h 50mDelta
Deal found 11/4$301
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/185:00 amSAT - EYW
2 stops8h 55mAmerican Airlines
Sat 11/225:40 pmEYW - SAT
1 stop6h 15mAmerican Airlines
Deal found 11/4$306

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Antonio to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 4, 2025.
Use the filters below to find and compare flights from San Antonio to Key West that are best for you.

Fly from

San Antonio

Fly to

Key West

Route

Depart

Return

Price

San AntonioKey West

SAT - EYW

SATEYW

San Antonio

Thu 12/4

11:53 am-9:45 pm

1 stop8h 52m

Key West

Wed 12/10

6:33 pm-12:25 am

1 stop6h 52m

$225

San AntonioKey West

SAT - EYW

SATEYW

San Antonio

Sat 12/13

1:40 pm-9:50 pm

1 stop7h 10m

Key West

Fri 12/19

4:03 pm-11:26 pm

1 stop8h 23m

$225

San AntonioKey West

SAT - EYW

SATEYW

San Antonio

Wed 12/17

11:36 am-8:06 pm

1 stop7h 30m

Key West

Mon 12/22

7:25 am-12:28 pm

1 stop6h 03m

$228

San AntonioKey West

SAT - EYW

SATEYW

San Antonio

Sat 1/3

9:51 am-3:48 pm

1 stop4h 57m

Key West

Fri 1/9

4:15 pm-11:15 pm

1 stop8h 00m

$259

San AntonioKey West

SAT - EYW

SATEYW

San Antonio

Sat 12/13

7:00 am-11:20 am

3 stops27h 20m

Key West

Fri 12/19

2:30 pm-11:26 pm

1 stop9h 56m

$292

San AntonioKey West

SAT - EYW

SATEYW

San Antonio

Sat 1/3

5:00 am-1:26 pm

1 stop7h 26m

Key West

Fri 1/9

2:43 pm-9:52 pm

1 stop8h 09m

$299

San AntonioKey West

SAT - EYW

SATEYW

San Antonio

Tue 11/18

8:00 am-2:03 pm

1 stop5h 03m

Key West

Sat 11/22

6:18 pm-12:08 am

1 stop6h 50m

$301

San AntonioKey West

SAT - EYW

SATEYW

San Antonio

Tue 11/18

5:00 am-2:55 pm

2 stops8h 55m

Key West

Sat 11/22

5:40 pm-10:55 pm

1 stop6h 15m

$306

San AntonioKey West

SAT - EYW

SATEYW

San Antonio

Sun 11/23

3:23 pm-9:17 am

2 stops16h 54m

Key West

Thu 11/27

12:15 pm-6:32 pm

1 stop7h 17m

$310

San AntonioKey West

SAT - EYW

SATEYW

San Antonio

Wed 11/12

7:37 pm-11:20 am

1 stop14h 43m

$219

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/4

Showing 1-10 of 11 results
1
2

Compare providers for flights from San Antonio to Key West

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Antonio to Key West in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on San Antonio-Key West flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on San Antonio-Key West flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from San Antonio-Key West flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Antonio-Key West flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Antonio-Key West flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Antonio to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from San Antonio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Antonio to Key West

What is the cheapest month to book a flight from San Antonio to Key West?

Currently, August is the cheapest month in which you can book a flight from San Antonio to Key West (average of $191). Flying from San Antonio to Key West in March is currently the most expensive (average of $326). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from San Antonio to Key West?

Reviews of airlines servicing Key West

Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated November 4, 2025.
Peruse reviews from past customers who have flown with Delta and American Airlines from San Antonio to Key West to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,003 reviews

Entertainment

7.9

Overall

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Delta
7.9
Good
8,003 reviews
Delta
7.9
Good
8,003 reviews

Entertainment

7.9

Overall

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
American Airlines
7.2
Good
11,040 reviews
Delta
7.9
Good
8,003 reviews

Entertainment

7.9

Overall

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Related info for your journey

Find useful and relevant information for your journey from San Antonio to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Antonio to Key West?

    Airlines like American Airlines, Delta, and United Airlines fly from San Antonio to Key West in about 4h 57m. The time it takes to get you to your destination can typically vary by up to 3h 55m. The distance from San Antonio to Key West is about 1082 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from San Antonio to Key West round-trip?

    Delta, at $227, was found to be the cheapest airline from San Antonio to Key West. An alternate airline flying to your destination would be American Airlines. Delta is currently priced 50% below the average price you’ll pay for this route.

  • Can I find deals for flights from San Antonio to Key West that include hotel bookings?

    Yes. In addition to deals on San Antonio to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Antonio to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Antonio to Key West.

  • Can I find deals for business class flights from San Antonio to Key West?

    Yes. Cheapflights offers flight deals from San Antonio to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Antonio to Key West?

    Currently, August is the cheapest month in which you can book a flight from San Antonio to Key West (average of $191). Flying from San Antonio to Key West in March is currently the most expensive (average of $326). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from San Antonio to Key West

Discover the top 2 airlines that operate flights from San Antonio to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$227Average$418FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$258Average$473FlexibilityNo cancel feeOn-time71%

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