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$130+ Cheap flights from San Antonio to Key West (SAT - EYW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/16. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — EYW
oct. 16 — oct. 231
jue. 10/16
jue. 10/23
1 adult, Economy
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Cheap flight deals from San Antonio to Key West

Discover tips and strategies to find the most affordable flight options for your journey from San Antonio (SAT) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septiembre 16, 2025.

Round-trip from

$191
(American Airlines)

One-way from

$130
(Kiwi.com)

Popular in

June

Cheapest in

August

Average price

$418
From San Antonio to Key West
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One-way flight from San Antonio to Key West
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Highest demand for flights based on searches. 9% potential increase in price ($46 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($17 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from San Antonio to Key West

Cheapest flights from San Antonio to Key West
Explore the most affordable flight options available from San Antonio to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 16, 2025.

This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/12:26 pmSAT - EYW
1 stop6h 30mAmerican Airlines
mar. 11/47:53 pmEYW - SAT
1 stop5h 06mAmerican Airlines
Deal found 9/15$191
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/12:00 pmSAT - EYW
1 stop5h 07mDelta
mar. 10/76:17 pmEYW - SAT
1 stop7h 03mDelta
Deal found 9/16$260
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/232:00 pmSAT - EYW
1 stop5h 07mDelta
mar. 9/306:10 pmEYW - SAT
1 stop6h 49mDelta
Deal found 9/14$261
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/179:11 amSAT - EYW
2 stops8h 48mAmerican Airlines
sáb. 9/207:31 pmEYW - SAT
1 stop5h 24mAmerican Airlines
Deal found 9/14$266
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/235:00 amSAT - EYW
2 stops11h 46mAmerican Airlines
mar. 9/3011:25 amEYW - SAT
2 stops10h 57mAmerican Airlines
Deal found 9/14$271
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/219:00 amSAT - EYW
2 stops9h 22mAmerican Airlines
sáb. 10/2511:22 amEYW - SAT
1 stop7h 14mAmerican Airlines
Deal found 9/14$308
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/302:00 pmSAT - EYW
1 stop5h 07mDelta
sáb. 10/46:10 pmEYW - SAT
1 stop6h 49mDelta
Deal found 9/15$315

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Antonio to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 16, 2025.
Use the filters below to find and compare flights from San Antonio to Key West that are best for you.

Fly from

San Antonio

Fly to

Key West

Route

Depart

Return

Price

San AntonioKey West

SAT - EYW

SATEYW

San Antonio

mié. 10/1

2:00 pm-8:07 pm

1 stop5h 07m

Key West

mar. 10/7

6:17 pm-12:20 am

1 stop7h 03m

$260

San AntonioKey West

SAT - EYW

SATEYW

San Antonio

mar. 10/21

9:00 am-7:22 pm

2 stops9h 22m

Key West

sáb. 10/25

11:22 am-5:36 pm

1 stop7h 14m

$308

San AntonioKey West

SAT - EYW

SATEYW

San Antonio

mar. 10/21

5:14 am-1:02 pm

1 stop6h 48m

Key West

sáb. 10/25

6:17 pm-12:20 am

1 stop7h 03m

$314

San AntonioKey West

SAT - EYW

SATEYW

San Antonio

mar. 9/30

2:00 pm-8:07 pm

1 stop5h 07m

Key West

sáb. 10/4

6:10 pm-11:59 pm

1 stop6h 49m

$315

San AntonioKey West

SAT - EYW

SATEYW

San Antonio

mié. 11/12

6:23 pm-7:46 pm

2 stops24h 23m

Key West

lun. 11/17

2:25 pm-3:11 pm

1 stop25h 46m

$323

San AntonioKey West

SAT - EYW

SATEYW

San Antonio

mar. 3/3

7:05 am-4:07 pm

1 stop8h 02m

Key West

sáb. 3/7

4:53 pm-9:13 pm

1 stop5h 20m

$339

San AntonioKey West

SAT - EYW

SATEYW

San Antonio

dom. 11/16

6:00 am-8:46 pm

1 stop13h 46m

$130

San AntonioKey West

SAT - EYW

SATEYW

San Antonio

mié. 1/28

10:45 am-7:44 pm

1 stop7h 59m

$271

San AntonioKey West

SAT - EYW

SATEYW

San Antonio

mié. 1/28

6:09 am-4:32 pm

2 stops9h 23m

$276

San AntonioKey West

SAT - EYW

SATEYW

San Antonio

mié. 1/28

11:43 am-1:02 pm

3 stops24h 19m

$508

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Best time to book a flight from San Antonio to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from San Antonio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Antonio to Key West

What is the cheapest month to book a flight from San Antonio to Key West?

Currently, August is the cheapest month in which you can book a flight from San Antonio to Key West (average of $328). Flying from San Antonio to Key West in March is currently the most expensive (average of $491). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Key West

Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated septiembre 16, 2025.
Peruse reviews from past customers who have flown with Delta and American Airlines from San Antonio to Key West to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,957 reviews

Boarding

8.2

Crew

8.5

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Delta
8.0
Very good
7,957 reviews
Delta
8.0
Very good
7,957 reviews

Boarding

8.2

Crew

8.5

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,957 reviews

Boarding

8.2

Crew

8.5

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Related info for your journey

Find useful and relevant information for your journey from San Antonio to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Antonio to Key West?

    Airlines like Delta and American Airlines fly from San Antonio to Key West in about 5h 07m. The time it takes to get you to your destination can typically vary by up to 4h 15m. The distance from San Antonio to Key West is about 1082 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from San Antonio to Key West round-trip?

    Delta, at $227, was found to be the cheapest airline from San Antonio to Key West. An alternate airline flying to your destination would be American Airlines. Delta is currently priced 51% below the average price you’ll pay for this route.

  • Can I find deals for flights from San Antonio to Key West that include hotel bookings?

    Yes. In addition to deals on San Antonio to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Antonio to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Antonio to Key West.

  • Can I find deals for business class flights from San Antonio to Key West?

    Yes. Cheapflights offers flight deals from San Antonio to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Antonio to Key West?

    Currently, August is the cheapest month in which you can book a flight from San Antonio to Key West (average of $328). Flying from San Antonio to Key West in March is currently the most expensive (average of $491). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from San Antonio to Key West

Discover the top 2 airlines that operate flights from San Antonio to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$227Average$418FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$236Average$476FlexibilityNo cancel feeOn-time71%

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