HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Key West

$117+ Cheap flights from Louisville to Key West (SDF - EYW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/8. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — EYW
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Louisville to Key West with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Louisville Intl to Key West are usually found in August or February, booked 64 days in advance, depart on a Saturday or Wednesday and return on a Monday

Cheap flight deals from Louisville to Key West

Cheapest flights from Louisville to Key West
Explore the most affordable flight options available from Louisville to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This Mytrip deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:05 amSDF - EYW
1 stop6h 15mSpirit Airlines
Sat 12/272:30 pmEYW - SDF
1 stop9h 29mSpirit Airlines
Deal found 12/8$268
This Mytrip deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:05 amSDF - EYW
1 stop6h 15mMultiple Airlines
Sat 12/273:14 pmEYW - SDF
2 stops8h 45mMultiple Airlines
Deal found 12/8$290
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/255:05 amSDF - EYW
1 stop6h 15mSpirit Airlines
Sat 12/272:30 pmEYW - SDF
1 stop9h 29mSpirit Airlines
Deal found 12/11$294
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/255:05 amSDF - EYW
2 stops28h 12mMultiple Airlines
Sat 12/272:30 pmEYW - SDF
1 stop9h 29mMultiple Airlines
Deal found 12/11$334
This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/142:55 pmSDF - EYW
1 stop19h 36mBreeze Airways
Tue 12/1611:45 amEYW - SDF
2 stops50h 30mBreeze Airways
Deal found 12/10$392
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:00 amSDF - EYW
1 stop7h 51mUnited Airlines
Sat 12/132:42 pmEYW - SDF
1 stop8h 50mUnited Airlines
Deal found 12/10$404
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/126:15 amSDF - EYW
1 stop6h 48mAmerican Airlines
Wed 12/174:10 pmEYW - SDF
2 stops7h 44mAmerican Airlines
Deal found 12/10$409
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1211:21 amSDF - EYW
1 stop26h 09mMultiple Airlines
Sun 12/1410:27 pmEYW - SDF
1 stop17h 09mMultiple Airlines
Deal found 12/8$427
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/113:39 pmSDF - EYW
2 stops7h 28mAmerican Airlines
Sat 12/133:18 pmEYW - SDF
1 stop6h 25mAmerican Airlines
Deal found 12/10$429
This Mytrip deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/285:05 amSDF - EYW
1 stop6h 15mSpirit Airlines
Thu 1/112:20 pmEYW - SDF
1 stop11h 39mSpirit Airlines
Deal found 12/10$433
This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/285:05 amSDF - EYW
2 stops40h 06mMultiple Airlines
Thu 1/112:20 pmEYW - SDF
1 stop11h 39mMultiple Airlines
Deal found 12/10$457

Find flight deals from Louisville to Key West

Discover tips and strategies to find the most affordable flight options for your journey from Louisville (SDF) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$250
(American Airlines)

One-way from

$117
(Mytrip)

Popular in

March

Cheapest in

August

Average price

$446
Provider with most accurate pricing for Louisville Intl-Key West flight deals.
Search Deals
Provider most trusted by Cheapflights users for Louisville Intl-Key West flights.
Search Deals
From Louisville Intl to Key West
Search Deals
One-way flight from Louisville Intl to Key West
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($25 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisville to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Louisville to Key West that are best for you.

Fly from

Louisville

Fly to

Key West

Route

Depart

Return

Price

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Sun 1/18

3:36 pm-1:30 pm

1 stop21h 54m

Key West

Thu 1/22

10:06 am-1:00 pm

1 stop26h 54m

$244

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Wed 1/14

8:07 am-6:01 pm

2 stops9h 54m

Key West

Sat 1/17

2:04 pm-9:16 pm

1 stop7h 12m

$255

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Sat 1/10

5:35 am-11:26 am

1 stop5h 51m

Key West

Tue 1/13

4:15 pm-10:30 pm

1 stop6h 15m

$259

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Wed 1/14

6:00 am-12:48 pm

1 stop6h 48m

Key West

Sat 1/17

7:10 am-11:33 am

1 stop4h 23m

$259

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Thu 1/8

3:33 pm-9:47 pm

1 stop6h 14m

Key West

Sun 1/11

6:06 am-11:15 am

1 stop5h 09m

$259

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Wed 1/7

3:33 pm-9:47 pm

1 stop6h 14m

Key West

Sun 1/11

6:06 am-11:15 am

1 stop5h 09m

$259

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Fri 1/9

3:33 pm-9:47 pm

1 stop6h 14m

Key West

Mon 1/12

4:37 pm-11:59 pm

1 stop7h 22m

$259

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Thu 1/8

3:36 pm-11:15 am

2 stops19h 39m

$149

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Sat 2/14

12:00 pm-10:21 am

2 stops22h 21m

$245

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Fri 1/9

3:37 pm-7:40 pm

1 stop4h 03m

$271

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/9

Showing 1-10 of 16 results
1
2

Compare providers for flights from Louisville to Key West

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Louisville to Key West in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Louisville-Key West flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Louisville-Key West flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Louisville-Key West flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Louisville-Key West flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Louisville-Key West flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Louisville to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from Louisville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisville to Key West

How far ahead should I book a flight from Louisville to Key West?

Use this chart to determine the optimal time to book a round-trip flight from Louisville to Key West. Price data was last updated on December 5, 2025.

To ensure you get the cheapest price possible for a flight from Louisville to Key West, you should look to book at least 64 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Louisville to Key West?

Currently, August is the cheapest month in which you can book a flight from Louisville to Key West (average of $96). Flying from Louisville to Key West in December is currently the most expensive (average of $204). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDF to EYW?

Find hourly flight availability from Louisville to Key West. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

One of the essential ways to save on airfare from Louisville to Key West is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight at noon could potentially save you up to 32% on airfare.

Reviews of airlines servicing Key West

Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated December 12, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Louisville to Key West have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,008 reviews

Boarding

8.1

Food

7.3

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,008 reviews
Delta
7.9
Good
8,008 reviews

Boarding

8.1

Food

7.3

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,095 reviews
Delta
7.9
Good
8,008 reviews

Boarding

8.1

Food

7.3

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,050 reviews
Delta
7.9
Good
8,008 reviews

Boarding

8.1

Food

7.3

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Louisville to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Louisville to Key West?

    Airlines like American Airlines and United Airlines fly from Louisville to Key West in about 5h 51m. The time it takes to get you to your destination can typically vary by up to 4h 03m. The distance between Louisville and Key West is about 969 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Louisville to Key West round-trip?

    Cheapflights users have booked flights from Louisville to Key West round-trip from $258. Other airlines that can offer you cheap pricing are Delta, from $258, and United Airlines, from $258. American Airlines is 37% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Louisville to Key West that include hotel bookings?

    Yes. In addition to deals on Louisville to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisville to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to Key West.

  • Can I find deals for business class flights from Louisville to Key West?

    Yes. Cheapflights offers flight deals from Louisville to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisville to Key West?

    Currently, August is the cheapest month in which you can book a flight from Louisville to Key West (average of $96). Flying from Louisville to Key West in December is currently the most expensive (average of $204). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Louisville to Key West

See prices for flight routes from nearby airports that may be better suited for you.
Cincinnati to Fort Lauderdale flights
Cincinnati to Orlando flights
Cincinnati to Tampa flights
Cincinnati to Fort Myers flights
Cincinnati to Miami flights
Nashville to Miami flights
Nashville to Orlando flights
Louisville to Miami flights
Nashville to Fort Lauderdale flights
Nashville to Tampa flights
Louisville to Orlando flights
Louisville to Fort Lauderdale flights
Cincinnati to Orlando Sanford Intl flights
Louisville to Tampa flights
Louisville to Fort Myers flights
Cincinnati to Sarasota flights
Lexington to Orlando flights
Lexington to Miami flights
Cincinnati to St Petersburg flights
Nashville to Fort Myers flights
Louisville to West Palm Beach flights
Cincinnati to Key West flights
Nashville to Key West flights
Knoxville to Orlando flights
Lexington to Fort Myers flights
Nashville to Sarasota flights
Knoxville to Fort Lauderdale flights
Lexington to Tampa flights
Nashville to West Palm Beach flights
Cincinnati to Punta Gorda flights
Nashville to St Petersburg flights
Cincinnati to Pensacola flights
Knoxville to Orlando Sanford Intl flights
Lexington to West Palm Beach flights
Nashville to Jacksonville flights
Cincinnati to West Palm Beach flights
Knoxville to Miami flights
Lexington to Fort Lauderdale flights
Louisville to Sarasota flights
Knoxville to Tampa flights
Lexington to Orlando Sanford Intl flights
Nashville to Pensacola flights
Cincinnati to Daytona Beach flights
Cincinnati to Panama City flights
Lexington to Sarasota flights
Lexington to Daytona Beach flights
Lexington to Pensacola flights
Cincinnati to Jacksonville flights
Evansville to Orlando flights

Top 3 airlines flying from Louisville to Key West

Discover the top 3 airlines that operate flights from Louisville to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$258Average$443FlexibilityNo cancel feeOn-time69%
DeltaCheapest$258Average$397FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$258Average$435FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.