$215+ Cheap flights from Key West to Louisville (EYW - SDF)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/6. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — SDF
Nov 1 — Nov 81
Round-trip
1 adult, Economy
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Find cheap flights from Key West to Louisville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Key West to Louisville
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Last-minute
One-way
Cheapest flights from Key West to LouisvilleExplore the most affordable flight options available from Key West to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 2, 2026.
Explore the most affordable flight options available from Key West to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 2, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/710:04 am -
2 stops47h 41m
Sun 10/119:18 pm -
1 stop13h 01m
Deal found 9/29![Multiple Airlines logo]()
$440
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:10 pm -
1 stop6h 20m
Tue 11/109:17 am -
1 stop6h 12m
Deal found 9/29![United Airlines logo]()
$449
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/72:15 pm -
1 stop9h 26m
Sun 10/116:15 am -
1 stop7h 14m
Deal found 9/29![United Airlines logo]()
$474
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/112:51 pm -
1 stop8h 39m
Sun 11/157:00 am -
1 stop8h 29m
Deal found 9/28![United Airlines logo]()
$523
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:40 am -
1 stop4h 40m
Mon 10/58:09 am -
1 stop4h 44m
Deal found 10/1![Delta logo]()
$529
This Kiwi.com deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/210:59 am -
2 stops33h 32m
Mon 10/510:25 am -
1 stop6h 22m
Deal found 10/1![Multiple Airlines logo]()
$546
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/211:30 am -
2 stops9h 57m
Mon 10/55:04 am -
2 stops7h 59m
Deal found 10/1![American Airlines logo]()
$777
This KAYAK deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/210:59 am -
2 stops33h 32m
Mon 10/511:39 am -
3 stops45h 45m
Deal found 10/1![Breeze Airways logo]()
$1,553
This KAYAK deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/710:04 am -
3 stops47h 41m
Sun 10/119:09 pm -
1 stop15h 10m
Deal found 9/29![Breeze Airways logo]()
$1,733
Best flights from Key West to LouisvilleDiscover carefully curated flight deals from Key West to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 2, 2026.
Discover carefully curated flight deals from Key West to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 2, 2026.
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:10 pm -
1 stop6h 20m
Tue 11/109:17 am -
1 stop6h 12m
Deal found 10/1![United Airlines logo]()
$449
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/112:51 pm -
1 stop8h 39m
Sun 11/157:00 am -
1 stop8h 29m
Deal found 9/27![United Airlines logo]()
$523
Last-minute flights from Key West to LouisvilleDiscover last-minute flight deals from Key West to Louisville. Data last updated October 2, 2026 and is based on user searches.
Discover last-minute flight deals from Key West to Louisville. Data last updated October 2, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:40 am -
1 stop4h 40m
Mon 10/58:09 am -
1 stop4h 44m
Deal found 10/1![Delta logo]()
$529
This Kiwi.com deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/210:59 am -
2 stops33h 32m
Mon 10/510:25 am -
1 stop6h 22m
Deal found 10/1![Multiple Airlines logo]()
$546
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/211:30 am -
2 stops9h 57m
Mon 10/55:04 am -
2 stops7h 59m
Deal found 10/1![American Airlines logo]()
$777
This KAYAK deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/210:59 am -
2 stops33h 32m
Mon 10/511:39 am -
3 stops45h 45m
Deal found 10/1![Breeze Airways logo]()
$1,553
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/710:04 am -
2 stops47h 41m
Sun 10/119:18 pm -
1 stop13h 01m
Deal found 9/29![Multiple Airlines logo]()
$440
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/72:15 pm -
1 stop9h 26m
Sun 10/116:15 am -
1 stop7h 14m
Deal found 9/29![United Airlines logo]()
$474
This KAYAK deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/710:04 am -
3 stops47h 41m
Sun 10/119:09 pm -
1 stop15h 10m
Deal found 9/29![Breeze Airways logo]()
$1,733
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:10 pm -
1 stop6h 20m
Tue 11/109:17 am -
1 stop6h 12m
Deal found 9/29![United Airlines logo]()
$449
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/112:51 pm -
1 stop8h 39m
Sun 11/157:00 am -
1 stop8h 29m
Deal found 9/28![United Airlines logo]()
$523
One-way flights from Key West to LouisvilleSearch for one-way flight options from Key West to Louisville. Find affordable one-way fares based on user searches. Data last updated October 2, 2026.
Search for one-way flight options from Key West to Louisville. Find affordable one-way fares based on user searches. Data last updated October 2, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/66:44 pm -
2 stops25h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/1![Multiple Airlines logo]()
$215
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/67:00 am -
1 stop4h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/1![Delta logo]()
$332
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1112:01 pm -
1 stop8h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Breeze Airways logo]()
$345
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/144:40 pm -
1 stop7h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![American Airlines logo]()
$352
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/1410:59 am -
3 stops30h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Multiple Airlines logo]()
$392
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:40 am -
1 stop7h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Delta logo]()
$402
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1110:59 am -
2 stops22h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Multiple Airlines logo]()
$404
This KAYAK deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1410:04 am -
2 stops10h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Breeze Airways logo]()
$434
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:10 pm -
1 stop4h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Delta logo]()
$451
Find flight deals from Key West to Louisville
Discover tips and strategies to find the most affordable flight options for your journey from Key West (EYW) to Louisville (SDF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 2, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $449 (United Airlines) |
One-way from | $215 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Key West to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 2, 2026.
Use the filters below to find and compare flights from Key West to Louisville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Key WestLouisville
EYW Key West - SDF Louisville Intl
EYWSDF
Key West
Wed 1/6
6:44 pm-8:29 pm
2 stops25h 45m
Louisville Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$215
Key WestLouisville
EYW Key West - SDF Louisville Intl
EYWSDF
Key West
Wed 1/6
7:00 am-11:36 am
1 stop4h 36m
Louisville Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$332
Key WestLouisville
EYW Key West - SDF Louisville Intl
EYWSDF
Key West
Sun 10/11
12:01 pm-8:29 pm
1 stop8h 28m
Louisville Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$345
Key WestLouisville
EYW Key West - SDF Louisville Intl
EYWSDF
Key West
Wed 10/14
2:00 pm-7:10 pm
1 stop5h 10m
Louisville Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$402
Key WestLouisville
EYW Key West - SDF Louisville Intl
EYWSDF
Key West
Sat 10/10
7:40 am-2:41 pm
1 stop7h 01m
Louisville Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$402
Key WestLouisville
EYW Key West - SDF Louisville Intl
EYWSDF
Key West
Tue 10/13
7:40 am-2:41 pm
1 stop7h 01m
Louisville Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$402
Key WestLouisville
EYW Key West - SDF Louisville Intl
EYWSDF
Key West
Fri 11/6
4:10 pm-10:30 pm
1 stop6h 20m
Louisville Intl
Tue 11/10
9:17 am-3:29 pm
1 stop6h 12m
$449
Key WestLouisville
EYW Key West - SDF Louisville Intl
EYWSDF
Key West
Thu 10/15
2:00 pm-8:35 pm
1 stop6h 35m
Louisville Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$451
Key WestLouisville
EYW Key West - SDF Louisville Intl
EYWSDF
Key West
Thu 10/15
12:48 pm-9:30 pm
2 stops8h 42m
Louisville Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$466
Quickest round-trip
Key WestLouisville
EYW Key West - SDF Louisville Intl
EYWSDF
Key West
Sun 10/11
6:10 pm-10:37 pm
1 stop4h 27m
Louisville Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$500
Showing 1-10 of 11 resultsSorted by cheapest first
Compare providers for flights from Key West to Louisville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Key West to Louisville in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Key West-Louisville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Key West-Louisville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Key West-Louisville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Key West-Louisville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Key West-Louisville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Key West to Louisville
Have a flexible travel schedule? Discover the best time to fly to Louisville from Key West with our price prediction graph.
EYW-SDF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Key West to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Louisville?
Book flights to Louisville if you plan to visit one of these locationsShepherdsville
Elizabethtown
Jeffersonville
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