$152+ Cheap flights from Louisville to Panama City, FL (SDF - ECP)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/1. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — ECP
Aug 3 — Aug 101
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Louisville to Panama City
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Last-minute
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Cheapest flights from Louisville to Panama CityExplore the most affordable flight options available from Louisville to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 4, 2026.
Explore the most affordable flight options available from Louisville to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 4, 2026.
This Delta deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:00 am
SDF
- ECP
1 stop5h 42m
Delta
Mon 8/317:35 am
ECP
- SDF
1 stop3h 46m
Delta
Deal found 6/29![Delta logo]()
$301
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:00 pm
SDF
- ECP
1 stop5h 58m
Delta
Sat 8/85:02 pm
ECP
- SDF
1 stop4h 03m
Delta
Deal found 7/2![Delta logo]()
$303
This Southwest deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:55 am
SDF
- ECP
2 stops9h 55m
Southwest
Sat 10/314:05 pm
ECP
- SDF
1 stop5h 15m
Southwest
Deal found 6/29![Southwest logo]()
$306
This Southwest deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:45 am
SDF
- ECP
1 stop5h 20m
Southwest
Wed 8/2611:30 am
ECP
- SDF
2 stops9h 00m
Southwest
Deal found 7/1![Southwest logo]()
$308
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/317:05 am
SDF
- ECP
1 stop4h 37m
Delta
Sun 9/66:00 am
ECP
- SDF
1 stop3h 32m
Delta
Deal found 7/2![Delta logo]()
$316
This Southwest deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:45 am
SDF
- ECP
2 stops12h 25m
Southwest
Sat 8/2210:30 am
ECP
- SDF
2 stops5h 55m
Southwest
Deal found 6/30![Southwest logo]()
$319
This Southwest deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:00 am
SDF
- ECP
2 stops10h 00m
Southwest
Mon 8/317:05 am
ECP
- SDF
1 stop5h 00m
Southwest
Deal found 6/29![Southwest logo]()
$320
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/178:05 am
SDF
- ECP
1 stop3h 37m
Delta
Tue 9/11:53 pm
ECP
- SDF
1 stop4h 40m
Delta
Deal found 7/3![Delta logo]()
$329
Best flights from Louisville to Panama CityDiscover carefully curated flight deals from Louisville to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 4, 2026.
Discover carefully curated flight deals from Louisville to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 4, 2026.
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/293:25 pm
SDF
- ECP
1 stop4h 10m
Delta
Sat 9/56:00 am
ECP
- SDF
1 stop3h 32m
Delta
Deal found 7/2![Delta logo]()
$303
This Southwest deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/114:00 pm
SDF
- ECP
1 stop3h 10m
Southwest
Sat 8/1510:30 am
ECP
- SDF
2 stops5h 55m
Southwest
Deal found 7/2![Southwest logo]()
$308
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/11:21 pm
SDF
- ECP
1 stop3h 41m
Delta
Wed 9/29:27 am
ECP
- SDF
1 stop3h 51m
Delta
Deal found 7/2![Delta logo]()
$303
This Southwest deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:45 am
SDF
- ECP
1 stop5h 20m
Southwest
Wed 8/2611:30 am
ECP
- SDF
2 stops9h 00m
Southwest
Deal found 7/1![Southwest logo]()
$308
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:00 pm
SDF
- ECP
1 stop5h 58m
Delta
Sat 8/85:02 pm
ECP
- SDF
1 stop4h 03m
Delta
Deal found 7/2![Delta logo]()
$303
This Southwest deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:00 am
SDF
- ECP
2 stops10h 00m
Southwest
Mon 8/317:05 am
ECP
- SDF
1 stop5h 00m
Southwest
Deal found 6/29![Southwest logo]()
$320
This Southwest deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/255:05 pm
SDF
- ECP
1 stop5h 55m
Southwest
Sat 8/14:40 pm
ECP
- SDF
1 stop4h 05m
Southwest
Deal found 7/2![Southwest logo]()
$341
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/318:10 am
SDF
- ECP
1 stop3h 38m
Delta
Wed 8/59:27 am
ECP
- SDF
1 stop3h 51m
Delta
Deal found 6/30![Delta logo]()
$345
This Southwest deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/128:20 am
SDF
- ECP
1 stop6h 35m
Southwest
Sat 9/199:30 am
ECP
- SDF
1 stop10h 50m
Southwest
Deal found 6/29![Southwest logo]()
$342
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/96:00 am
SDF
- ECP
1 stop3h 31m
Delta
Mon 8/106:00 am
ECP
- SDF
1 stop3h 32m
Delta
Deal found 7/3![Delta logo]()
$358
Last-minute flights from Louisville to Panama CityDiscover last-minute flight deals from Louisville to Panama City. Data last updated July 4, 2026 and is based on user searches.
Discover last-minute flight deals from Louisville to Panama City. Data last updated July 4, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:00 pm
SDF
- ECP
1 stop5h 58m
Delta
Sat 8/85:02 pm
ECP
- SDF
1 stop4h 03m
Delta
Deal found 7/2![Delta logo]()
$303
This Southwest deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/133:20 pm
SDF
- ECP
2 stops6h 40m
Southwest
Mon 8/177:05 am
ECP
- SDF
1 stop5h 00m
Southwest
Deal found 7/1![Southwest logo]()
$334
This Southwest deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:45 am
SDF
- ECP
2 stops12h 25m
Southwest
Sat 8/2210:30 am
ECP
- SDF
2 stops5h 55m
Southwest
Deal found 6/30![Southwest logo]()
$319
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/178:05 am
SDF
- ECP
1 stop3h 37m
Delta
Tue 9/11:53 pm
ECP
- SDF
1 stop4h 40m
Delta
Deal found 7/3![Delta logo]()
$329
This Southwest deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:45 am
SDF
- ECP
1 stop5h 20m
Southwest
Wed 8/2611:30 am
ECP
- SDF
2 stops9h 00m
Southwest
Deal found 7/1![Southwest logo]()
$308
This Delta deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:00 am
SDF
- ECP
1 stop5h 42m
Delta
Mon 8/317:35 am
ECP
- SDF
1 stop3h 46m
Delta
Deal found 6/29![Delta logo]()
$301
This Southwest deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:00 am
SDF
- ECP
2 stops10h 00m
Southwest
Mon 8/317:05 am
ECP
- SDF
1 stop5h 00m
Southwest
Deal found 6/29![Southwest logo]()
$320
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/317:05 am
SDF
- ECP
1 stop4h 37m
Delta
Sun 9/66:00 am
ECP
- SDF
1 stop3h 32m
Delta
Deal found 7/2![Delta logo]()
$316
One-way flights from Louisville to Panama CitySearch for one-way flight options from Louisville to Panama City. Find affordable one-way fares based on user searches. Data last updated July 4, 2026.
Search for one-way flight options from Louisville to Panama City. Find affordable one-way fares based on user searches. Data last updated July 4, 2026.
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:00 am
SDF
- ECP
1 stop3h 12m
Delta
Deal found 6/30![Delta logo]()
$152
This Southwest deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:00 am
SDF
- ECP
2 stops10h 00m
Southwest
Deal found 7/2![Southwest logo]()
$157
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:55 pm
SDF
- ECP
1 stop4h 30m
Delta
Deal found 7/3![Delta logo]()
$165
This Southwest deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/301:15 pm
SDF
- ECP
2 stops5h 55m
Southwest
Deal found 7/3![Southwest logo]()
$170
This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/316:00 am
SDF
- ECP
1 stop3h 12m
Delta
Deal found 7/1![Delta logo]()
$194
This Southwest deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/228:45 am
SDF
- ECP
2 stops7h 55m
Southwest
Deal found 6/30![Southwest logo]()
$195
This Southwest deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/283:20 pm
SDF
- ECP
2 stops6h 40m
Southwest
Deal found 7/3![Southwest logo]()
$199
This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/186:00 pm
SDF
- ECP
1 stop5h 58m
Delta
Deal found 7/1![Delta logo]()
$234
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2910:00 am
SDF
- ECP
2 stops13h 18m
United Airlines
Deal found 7/3![United Airlines logo]()
$239
This American Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/196:00 am
SDF
- ECP
1 stop7h 04m
American Airlines
Deal found 7/3![American Airlines logo]()
$251
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3111:06 am
SDF
- ECP
2 stops8h 16m
American Airlines
Deal found 6/30![American Airlines logo]()
$255
Find flight deals from Louisville to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Louisville (SDF) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $301 (American Airlines) |
One-way from | $152 (Delta) |
Popular in | April |
Cheapest in | November |
Average price | $466 |
Cheapflights Fare Finder
Customize your flight search to find flights from Louisville to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 4, 2026.
Use the filters below to find and compare flights from Louisville to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
LouisvillePanama City
SDF - ECP
SDFECP
Louisville Intl
Sat 8/29
3:25 pm-6:35 pm
1 stop4h 10m
Panama City NW Florida Beaches
Sat 9/5
6:00 am-10:32 am
1 stop3h 32m
$303
LouisvillePanama City
SDF - ECP
SDFECP
Louisville Intl
Tue 9/1
1:21 pm-4:02 pm
1 stop3h 41m
Panama City NW Florida Beaches
Wed 9/2
9:27 am-2:18 pm
1 stop3h 51m
$303
LouisvillePanama City
SDF - ECP
SDFECP
Louisville Intl
Sat 8/1
6:00 pm-10:58 pm
1 stop5h 58m
Panama City NW Florida Beaches
Sat 8/8
5:02 pm-10:05 pm
1 stop4h 03m
$303
LouisvillePanama City
SDF - ECP
SDFECP
Louisville Intl
Tue 8/11
4:00 pm-6:10 pm
1 stop3h 10m
Panama City NW Florida Beaches
Sat 8/15
10:30 am-5:25 pm
2 stops5h 55m
$308
LouisvillePanama City
SDF - ECP
SDFECP
Louisville Intl
Sat 8/22
6:45 am-11:05 am
1 stop5h 20m
Panama City NW Florida Beaches
Wed 8/26
11:30 am-9:30 pm
2 stops9h 00m
$308
LouisvillePanama City
SDF - ECP
SDFECP
Louisville Intl
Wed 8/26
6:00 am-3:00 pm
2 stops10h 00m
Panama City NW Florida Beaches
Mon 8/31
7:05 am-1:05 pm
1 stop5h 00m
$320
LouisvillePanama City
SDF - ECP
SDFECP
Louisville Intl
Sat 7/25
5:05 pm-10:00 pm
1 stop5h 55m
Panama City NW Florida Beaches
Sat 8/1
4:40 pm-9:45 pm
1 stop4h 05m
$341
LouisvillePanama City
SDF - ECP
SDFECP
Louisville Intl
Sat 9/12
8:20 am-1:55 pm
1 stop6h 35m
Panama City NW Florida Beaches
Sat 9/19
9:30 am-9:20 pm
1 stop10h 50m
$342
LouisvillePanama City
SDF - ECP
SDFECP
Louisville Intl
Fri 7/31
8:10 am-10:48 am
1 stop3h 38m
Panama City NW Florida Beaches
Wed 8/5
9:27 am-2:18 pm
1 stop3h 51m
$345
Quickest round-trip
LouisvillePanama City
SDF - ECP
SDFECP
Louisville Intl
Sun 8/9
6:00 am-8:31 am
1 stop3h 31m
Panama City NW Florida Beaches
Mon 8/10
6:00 am-10:32 am
1 stop3h 32m
$358
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from Louisville to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Louisville to Panama City in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Louisville-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Louisville-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Louisville-Panama City, Florida flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Louisville-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Louisville-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Louisville to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Louisville with our price prediction graph.
SDF-ECP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Louisville to Panama City
Prices
More
How far ahead should I book a flight from Louisville to Panama City, Florida?
To ensure you get the cheapest price possible for a flight from Louisville to Panama City, Florida, you should look to book at least 46 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Louisville to Panama City, Florida?
Currently, November is the cheapest month in which you can book a flight from Louisville to Panama City, Florida (average of $307). Flying from Louisville to Panama City, Florida in April is currently the most expensive (average of $582). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Louisville to Panama City, Florida?
What’s the top layover airport for flights from Louisville to Panama City, Florida?
Share of 1-stop round-trip flights from Louisville to Panama City, Florida chosen by Cheapflights users in the past 12 months, using the same layover each way.
Chicago (ORD) – chosen by Cheapflights users on 33% of 1-stop itineraries from Louisville to Panama City, Florida on Cheapflights.
What’s the cheapest layover airport for flights from Louisville to Panama City, Florida?
Average round-trip fare for 1-stop flights from Louisville to Panama City, Florida, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Charlotte (CLT) is the most affordable 1-stop option, with an average round-trip price of $386.
What’s the fastest layover option from Louisville to Panama City, Florida?
Shortest average travel time for 1-stop one-way flights from Louisville to Panama City, Florida, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Nashville (BNA) have the shortest average one-way travel time for 1-stop routes: 3h 10m.
Which airport typically offers the quickest layover for flights from Louisville to Panama City, Florida?
Average layover duration for 1-stop one-way flights from Louisville to Panama City, Florida, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Charlotte (CLT) offer the fastest connection on this route, with an average layover time of 0h 52m.
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated July 4, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andAmerican Airlines from Louisville to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Overall
7.9
Boarding
8.1
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Crew
8.6
Overall
7.9
Boarding
8.1
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Crew
8.6
Overall
7.9
Boarding
8.1
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Crew
8.6
Overall
7.9
Boarding
8.1
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Related info for your journey
Find useful and relevant information for your journey from Louisville to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Panama City?
Book flights to Panama City if you plan to visit one of these locationsMexico Beach
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Louisville and Panama City flights
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Top 3 airlines flying from Louisville to Panama City
Discover the top 3 airlines that operate flights from Louisville to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$238 | Average$381 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$242 | Average$391 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$325 | Average$463 | FlexibilityNo cancel fee | On-time63% |