What are the cheapest airlines flying from Louisville to Panama City, Florida round-trip?

According to our current data, Southwest ($237), Delta ($239), and American Airlines ($252) offers the cheapest pricing from Louisville to Panama City, Florida. Southwest is currently priced 36% below the average price you’ll pay for this route.

What are the cheapest airlines to fly from Louisville to Panama City, Florida one-way?

One-way options have recently been found by users for as low as $119 on United Airlines. Other airlines that offer cheap prices include American Airlines from $124 and Southwest from $226 one-way.

What is the cheapest day to fly from Louisville to Panama City, Florida?

Travelers seeking maximum savings on their Louisville to Panama City, Florida flight should consider departing on Saturday evenings when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Panama City, Florida ranges from 2.8 - 7.9 inches per month. July is typically the wettest month, when rainfall can reach 7.9 in. May is typically the driest time to visit Panama City, Florida when rainfall is around 2.8 in.

If weather is an important factor for your trip to Panama City, Florida, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 53.6 F).

What are the most popular airlines that fly from Louisville to Panama City, Florida?

Consider American Airlines, Delta or Southwest when booking your flight. These represent the most popular airlines when flying from Louisville to Panama City, Florida.

What is the cheapest day to fly round-trip from Louisville to Panama City, Florida?

Monday flights are generally found to be more expensive for flights from Louisville to Panama City, Florida. This shouldn’t discourage you from searching, as you can still find great deals by being flexible with your options. Use our search form to find deals on tickets to Panama City, Florida.

How far in advance should I book a flight from Louisville to Panama City, Florida?

Users have found that booking a flight from Louisville to Panama City, Florida at least 61 days early can save you up to 110% on average compared to booking a flight this week. If booking 61 days before your flight isn’t an option for you, users have found flights from Louisville to Panama City, Florida for as little as $282 when booking for a departure date within the next two weeks. You can also check prices now. Some users have found airline tickets as low as $568 for flights departing within the next 3 days.

What is the cheapest month to fly from Louisville to Panama City, Florida?

August can be a great time to fly to Panama City, Florida from Louisville with a flight ticket averaging about $372. Cheapflights users have found deals in the month of August for as cheap as $227. The most expensive prices can be found in the month of January.

Can I find deals for flights from Louisville to Panama City that include hotel bookings?

Yes. In addition to deals on Louisville to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Louisville to Panama City?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to Panama City.

Can I find deals for business class flights from Louisville to Panama City?

Yes. Cheapflights offers flight deals from Louisville to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$119+ Flights from Louisville to Panama City, FL

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Find cheap flights from Louisville to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Louisville Intl to Panama City NW Florida Beaches are usually found in August or September, booked 60 days in advance, depart on a Wednesday or Monday and return on a Tuesday

Cheap flight deals from Louisville to Panama City

Round-trip from	$237 (Southwest)
One-way from	$119 (United Airlines)
Popular in	January
Cheapest in	August
Average price	$346

From Louisville Intl to Panama City NW Florida Beaches

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One-way flight from Louisville Intl to Panama City NW Florida Beaches

Search Deals

Highest demand for flights based on searches. 11% potential increase in price ($47 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).

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Average for round-trip flights in July 2025

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Find flight deals from Louisville to Panama City

Cheapest flights from Louisville to Panama City
Explore the most affordable flight options available from Louisville to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.

Thu 9/46:25 amSDF - ECP

1 stop4h 30mSouthwest

Mon 9/86:35 amECP - SDF

1 stop7h 15mSouthwest

Deal found 6/30

$237

Tue 9/308:10 amSDF - ECP

1 stop6h 10mDelta

Fri 10/36:00 amECP - SDF

1 stop4h 43mDelta

Deal found 6/30

$239

Fri 8/2210:50 amSDF - ECP

2 stops7h 40mAmerican Airlines

Wed 8/2710:18 amECP - SDF

1 stop5h 08mAmerican Airlines

Deal found 6/30

$252

Best flights from Louisville to Panama City
Discover carefully curated flight deals from Louisville to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 2, 2025.

Thu 9/46:25 amSDF - ECP

1 stop4h 30mSouthwest

Mon 9/86:35 amECP - SDF

1 stop7h 15mSouthwest

Deal found 6/30

$237

Tue 9/308:10 amSDF - ECP

1 stop6h 10mDelta

Fri 10/36:00 amECP - SDF

1 stop4h 43mDelta

Deal found 6/30

$239

Fri 8/2210:50 amSDF - ECP

2 stops7h 40mAmerican Airlines

Wed 8/2710:18 amECP - SDF

1 stop5h 08mAmerican Airlines

Deal found 6/30

$252

Tue 7/297:00 amSDF - ECP

2 stops10h 21mUnited Airlines

Fri 8/12:05 pmECP - SDF

1 stop5h 21mUnited Airlines

Deal found 6/29

$422

Last-minute flights from Louisville to Panama City
Discover last-minute flight deals from Louisville to Panama City. Data last updated July 2, 2025 and is based on user searches.

Tue 7/87:05 amSDF - ECP

1 stop6h 14mDelta

Tue 7/84:52 pmECP - SDF

1 stop3h 59mDelta

Deal found 7/1

$513

Wed 7/91:00 pmSDF - ECP

2 stops9h 10mSouthwest

Mon 7/1412:35 pmECP - SDF

2 stops6h 20mSouthwest

Deal found 6/29

$496

Sat 7/124:46 pmSDF - ECP

1 stop6h 17mAmerican Airlines

Sat 7/193:12 pmECP - SDF

1 stop6h 58mAmerican Airlines

Deal found 6/30

$460

Sat 7/123:39 pmSDF - ECP

1 stop7h 21mUnited Airlines

Sat 7/196:30 amECP - SDF

2 stops13h 29mUnited Airlines

Deal found 7/1

$573

Tue 7/293:21 pmSDF - ECP

1 stop3h 47mDelta

Wed 8/66:00 amECP - SDF

1 stop4h 45mDelta

Deal found 6/29

$247

Sat 8/1610:40 amSDF - ECP

2 stops8h 35mAmerican Airlines

Thu 8/212:33 pmECP - SDF

1 stop4h 03mAmerican Airlines

Deal found 7/2

$252

Sat 8/166:43 amSDF - ECP

2 stops10h 38mUnited Airlines

Thu 8/216:30 amECP - SDF

2 stops9h 45mUnited Airlines

Deal found 7/2

$419

Sun 8/317:15 amSDF - ECP

2 stops10h 00mSouthwest

Sat 9/610:55 amECP - SDF

2 stops9h 50mSouthwest

Deal found 7/1

$287

One-way flights from Louisville to Panama City
Search for one-way flight options from Louisville to Panama City. Find affordable one-way fares based on user searches. Data last updated July 2, 2025.

Wed 8/69:35 amSDF - ECP

1 stop7h 46mUnited Airlines

Deal found 6/30

$119

Wed 8/610:50 amSDF - ECP

2 stops7h 40mAmerican Airlines

Deal found 6/30

$124

Sun 7/206:40 amSDF - ECP

2 stops7h 35mSouthwest

Deal found 7/2

$226

Thu 7/103:21 pmSDF - ECP

1 stop6h 03mDelta

Deal found 7/1

$257

Cheapflights Fare Finder

Use the filters below to find and compare flights from Louisville to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Thu 9/4

6:25 am-9:55 am

1 stop4h 30m

Panama City NW Florida Beaches

Mon 9/8

6:35 am-2:50 pm

1 stop7h 15m

$237

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Tue 9/30

8:10 am-1:20 pm

1 stop6h 10m

Panama City NW Florida Beaches

Fri 10/3

6:00 am-11:43 am

1 stop4h 43m

$239

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Sat 8/16

10:40 am-6:15 pm

2 stops8h 35m

Panama City NW Florida Beaches

Thu 8/21

2:33 pm-7:36 pm

1 stop4h 03m

$252

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Sat 8/16

6:43 am-4:21 pm

2 stops10h 38m

Panama City NW Florida Beaches

Thu 8/21

6:30 am-5:15 pm

2 stops9h 45m

$419

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Wed 8/6

9:35 am-4:21 pm

1 stop7h 46m

$119

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Wed 8/6

10:50 am-5:30 pm

2 stops7h 40m

$124

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Sun 7/20

7:05 am-10:34 am

1 stop4h 29m

$204

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Sun 7/20

6:40 am-1:15 pm

2 stops7h 35m

$226

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/30

Best time to book a flight from Louisville to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Louisville with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisville to Panama City

How far ahead should I book a flight from Louisville to Panama City, Florida?

To ensure you get the cheapest price possible for a flight from Louisville to Panama City, Florida, you should look to book at least 60 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Louisville to Panama City, Florida?

Currently, January is the cheapest month in which you can book a flight from Louisville to Panama City, Florida (average of $346). Flying from Louisville to Panama City, Florida in March is currently the most expensive (average of $461). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDF to ECP?

Unlike in the morning, when flights are generally more expensive, you can save up to 23% on flights from Louisville to Panama City, Florida by exploring options for tickets in the evening.

Reviews of airlines servicing Panama City

Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Louisville to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,272 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Southwest

8.0

Very good

4,272 reviews

Southwest

8.0

Very good

4,272 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Delta

8.0

Very good

7,983 reviews

Southwest

8.0

Very good

4,272 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

United Airlines

7.4

Good

8,861 reviews

Southwest

8.0

Very good

4,272 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

American Airlines

7.2

Good

10,000 reviews

Southwest

8.0

Very good

4,272 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

What are the cheapest airlines flying from Louisville to Panama City, Florida round-trip?
According to our current data, Southwest ($237), Delta ($239), and American Airlines ($252) offers the cheapest pricing from Louisville to Panama City, Florida. Southwest is currently priced 36% below the average price you’ll pay for this route.
What are the cheapest airlines to fly from Louisville to Panama City, Florida one-way?
One-way options have recently been found by users for as low as $119 on United Airlines. Other airlines that offer cheap prices include American Airlines from $124 and Southwest from $226 one-way.
Can I find deals for flights from Louisville to Panama City that include hotel bookings?
Yes. In addition to deals on Louisville to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Louisville to Panama City?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to Panama City.
Can I find deals for business class flights from Louisville to Panama City?
Yes. Cheapflights offers flight deals from Louisville to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Louisville to Panama City, Florida?
Currently, January is the cheapest month in which you can book a flight from Louisville to Panama City, Florida (average of $346). Flying from Louisville to Panama City, Florida in March is currently the most expensive (average of $461). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Mexico Beach

Browse thousands of different options on Cheapflights for your next trip

Top 3 airlines flying from Louisville to Panama City

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$228	Average$357	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$256	Average$359	FlexibilityNo cancel fee	On-time71%
Southwest	Cheapest$296	Average$382	FlexibilityNo cancel fee	On-time63%

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$119+ Cheap flights from Louisville to Panama City, FL (SDF - ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/6. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Louisville to Panama City with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Louisville Intl to Panama City NW Florida Beaches are usually found in August or September, booked 60 days in advance, depart on a Wednesday or Monday and return on a Tuesday

Cheap flight deals from Louisville to Panama City

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Louisville to Panama City

Cheapest flights from Louisville to Panama CityExplore the most affordable flight options available from Louisville to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.

Explore the most affordable flight options available from Louisville to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Louisville to Panama City that are best for you.

Best time to book a flight from Louisville to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Louisville with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Louisville to Panama City

How far ahead should I book a flight from Louisville to Panama City, Florida?

Use this chart to determine the optimal time to book a round-trip flight from Louisville to Panama City. Price data was last updated on June 27, 2025.

What is the cheapest month to book a flight from Louisville to Panama City, Florida?

What is the cheapest time of day to fly from SDF to ECP?

Find hourly flight availability from Louisville to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 2, 2025.

Reviews of airlines servicing Panama City

Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Louisville to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Louisville to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Louisville to Panama City, Florida round-trip?

What are the cheapest airlines to fly from Louisville to Panama City, Florida one-way?

Can I find deals for flights from Louisville to Panama City that include hotel bookings?

How can I find direct flights from Louisville to Panama City?

Can I find deals for business class flights from Louisville to Panama City?

What is the cheapest month to book a flight from Louisville to Panama City, Florida?

Traveling to a place near Louisville?

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Alternative routes for Louisville to Panama City

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Louisville to Panama City

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Cheapest flights from Louisville to Panama City
Explore the most affordable flight options available from Louisville to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.