$155+ Cheap flights from Panama City, FL to Louisville (ECP - SDF)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/26. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — SDF
Sep 2 — Sep 91
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to Louisville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to Louisville
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Best
Last-minute
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Cheapest flights from Panama City to LouisvilleExplore the most affordable flight options available from Panama City to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 3, 2026.
Explore the most affordable flight options available from Panama City to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 3, 2026.
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/29:27 am
ECP
- SDF
1 stop6h 33m
Delta
Sat 9/55:50 pm
SDF
- ECP
1 stop4h 50m
Delta
Deal found 7/30![Delta logo]()
$309
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:30 pm
ECP
- SDF
1 stop5h 29m
Delta
Fri 9/116:00 am
SDF
- ECP
1 stop5h 34m
Delta
Deal found 8/1![Delta logo]()
$311
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:30 pm
ECP
- SDF
1 stop3h 29m
Delta
Sat 9/123:43 pm
SDF
- ECP
1 stop4h 25m
Delta
Deal found 8/1![Delta logo]()
$313
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:45 am
ECP
- SDF
1 stop3h 25m
Southwest
Sun 9/66:30 am
SDF
- ECP
2 stops10h 35m
Southwest
Deal found 7/30![Southwest logo]()
$314
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/29:10 am
ECP
- SDF
1 stop6h 10m
Southwest
Sat 9/56:45 am
SDF
- ECP
2 stops12h 30m
Southwest
Deal found 7/30![Southwest logo]()
$320
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:35 am
ECP
- SDF
1 stop5h 43m
Delta
Mon 9/76:00 am
SDF
- ECP
1 stop3h 31m
Delta
Deal found 7/31![Delta logo]()
$324
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/101:46 pm
ECP
- SDF
1 stop4h 44m
Delta
Tue 9/151:15 pm
SDF
- ECP
1 stop3h 16m
Delta
Deal found 8/1![Delta logo]()
$326
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:20 pm
ECP
- SDF
1 stop4h 39m
Delta
Sat 10/176:00 am
SDF
- ECP
1 stop3h 14m
Delta
Deal found 7/31![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:20 pm
ECP
- SDF
1 stop4h 39m
Delta
Thu 10/226:00 am
SDF
- ECP
1 stop3h 14m
Delta
Deal found 7/31![Delta logo]()
$354
This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1011:41 am
ECP
- SDF
1 stop7h 14m
United Airlines
Sun 9/137:10 am
SDF
- ECP
1 stop7h 03m
United Airlines
Deal found 8/1![United Airlines logo]()
$355
Best flights from Panama City to LouisvilleDiscover carefully curated flight deals from Panama City to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 3, 2026.
Discover carefully curated flight deals from Panama City to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 3, 2026.
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/52:20 pm
ECP
- SDF
1 stop6h 58m
American Airlines
Mon 9/78:16 am
SDF
- ECP
1 stop3h 56m
American Airlines
Deal found 7/29![American Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:00 am
ECP
- SDF
1 stop5h 21m
Delta
Thu 8/206:00 am
SDF
- ECP
1 stop3h 31m
Delta
Deal found 7/29![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/24:20 pm
ECP
- SDF
1 stop3h 15m
Southwest
Sun 9/67:55 am
SDF
- ECP
1 stop3h 15m
Southwest
Deal found 7/30![Southwest logo]()
$309
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/29:10 am
ECP
- SDF
1 stop6h 10m
Southwest
Sat 9/56:45 am
SDF
- ECP
2 stops12h 30m
Southwest
Deal found 7/30![Southwest logo]()
$320
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:20 pm
ECP
- SDF
1 stop4h 39m
Delta
Mon 10/198:05 am
SDF
- ECP
1 stop5h 45m
Delta
Deal found 7/31![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/149:19 am
ECP
- SDF
1 stop4h 22m
Delta
Fri 10/167:55 pm
SDF
- ECP
1 stop4h 23m
Delta
Deal found 7/31![Delta logo]()
$354
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:00 am
ECP
- SDF
1 stop3h 21m
Delta
Sun 10/185:59 pm
SDF
- ECP
1 stop6h 19m
Delta
Deal found 7/31![Delta logo]()
$368
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:20 pm
ECP
- SDF
1 stop4h 39m
Delta
Wed 10/216:00 am
SDF
- ECP
1 stop3h 14m
Delta
Deal found 7/31![Delta logo]()
$368
Last-minute flights from Panama City to LouisvilleDiscover last-minute flight deals from Panama City to Louisville. Data last updated August 3, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Louisville. Data last updated August 3, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:00 am
ECP
- SDF
1 stop5h 21m
Delta
Thu 8/206:00 am
SDF
- ECP
1 stop3h 31m
Delta
Deal found 7/29![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:40 am
ECP
- SDF
1 stop6h 24m
American Airlines
Thu 8/207:12 pm
SDF
- ECP
1 stop4h 28m
American Airlines
Deal found 7/30![American Airlines logo]()
$393
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/199:10 am
ECP
- SDF
2 stops10h 25m
Southwest
Thu 8/202:15 pm
SDF
- ECP
2 stops5h 45m
Southwest
Deal found 7/29![Southwest logo]()
$420
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/233:06 pm
ECP
- SDF
1 stop5h 19m
American Airlines
Tue 8/256:05 am
SDF
- ECP
1 stop6h 07m
American Airlines
Deal found 8/3![American Airlines logo]()
$408
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/238:10 am
ECP
- SDF
1 stop5h 00m
Southwest
Tue 8/256:00 am
SDF
- ECP
2 stops10h 00m
Southwest
Deal found 8/3![Southwest logo]()
$413
This Delta deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/236:00 am
ECP
- SDF
1 stop3h 32m
Delta
Sun 8/303:34 pm
SDF
- ECP
1 stop5h 34m
Delta
Deal found 8/2![Delta logo]()
$417
This American Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/236:57 pm
ECP
- SDF
1 stop4h 19m
American Airlines
Sun 8/307:31 am
SDF
- ECP
2 stops7h 19m
American Airlines
Deal found 8/2![American Airlines logo]()
$452
One-way flights from Panama City to LouisvilleSearch for one-way flight options from Panama City to Louisville. Find affordable one-way fares based on user searches. Data last updated August 3, 2026.
Search for one-way flight options from Panama City to Louisville. Find affordable one-way fares based on user searches. Data last updated August 3, 2026.
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/262:50 pm
ECP
- SDF
1 stop6h 20m
United Airlines
Deal found 7/30![United Airlines logo]()
$155
This Delta deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:00 am
ECP
- SDF
1 stop3h 19m
Delta
Deal found 8/2![Delta logo]()
$157
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2610:30 am
ECP
- SDF
2 stops6h 00m
Southwest
Deal found 7/30![Southwest logo]()
$160
This Southwest deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1210:30 am
ECP
- SDF
2 stops6h 00m
Southwest
Deal found 8/2![Southwest logo]()
$162
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/304:20 pm
ECP
- SDF
1 stop3h 20m
Southwest
Deal found 7/31![Southwest logo]()
$170
This Delta deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/275:15 pm
ECP
- SDF
1 stop3h 17m
Delta
Deal found 8/2![Delta logo]()
$185
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/138:05 am
ECP
- SDF
1 stop6h 44m
American Airlines
Deal found 7/31![American Airlines logo]()
$199
This Southwest deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/238:10 am
ECP
- SDF
1 stop5h 00m
Southwest
Deal found 8/2![Southwest logo]()
$209
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1311:30 am
ECP
- SDF
2 stops9h 05m
Southwest
Deal found 7/31![Southwest logo]()
$235
Find flight deals from Panama City to Louisville
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Louisville (SDF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $309 (Delta) |
One-way from | $155 (United Airlines) |
Popular in | December |
Cheapest in | August |
Average price | $302 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 3, 2026.
Use the filters below to find and compare flights from Panama City to Louisville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityLouisville
ECP - SDF
ECPSDF
Panama City NW Florida Beaches
Sat 9/5
2:20 pm-10:18 pm
1 stop6h 58m
Louisville Intl
Mon 9/7
8:16 am-11:12 am
1 stop3h 56m
$309
Panama CityLouisville
ECP - SDF
ECPSDF
Panama City NW Florida Beaches
Wed 8/19
6:00 am-12:21 pm
1 stop5h 21m
Louisville Intl
Thu 8/20
6:00 am-8:31 am
1 stop3h 31m
$309
Quickest round-trip
Panama CityLouisville
ECP - SDF
ECPSDF
Panama City NW Florida Beaches
Wed 9/2
4:20 pm-8:35 pm
1 stop3h 15m
Louisville Intl
Sun 9/6
7:55 am-10:10 am
1 stop3h 15m
$309
Panama CityLouisville
ECP - SDF
ECPSDF
Panama City NW Florida Beaches
Wed 9/2
9:10 am-4:20 pm
1 stop6h 10m
Louisville Intl
Sat 9/5
6:45 am-6:15 pm
2 stops12h 30m
$320
Panama CityLouisville
ECP - SDF
ECPSDF
Panama City NW Florida Beaches
Wed 10/14
6:20 pm-11:59 pm
1 stop4h 39m
Louisville Intl
Mon 10/19
8:05 am-12:50 pm
1 stop5h 45m
$339
Panama CityLouisville
ECP - SDF
ECPSDF
Panama City NW Florida Beaches
Wed 10/14
9:19 am-2:41 pm
1 stop4h 22m
Louisville Intl
Fri 10/16
7:55 pm-11:18 pm
1 stop4h 23m
$354
Panama CityLouisville
ECP - SDF
ECPSDF
Panama City NW Florida Beaches
Wed 10/14
6:00 am-10:21 am
1 stop3h 21m
Louisville Intl
Sun 10/18
5:59 pm-11:18 pm
1 stop6h 19m
$368
Panama CityLouisville
ECP - SDF
ECPSDF
Panama City NW Florida Beaches
Mon 10/12
6:20 pm-11:59 pm
1 stop4h 39m
Louisville Intl
Wed 10/21
6:00 am-8:14 am
1 stop3h 14m
$368
Cheapest one-way
Panama CityLouisville
ECP - SDF
ECPSDF
Panama City NW Florida Beaches
Sat 9/26
2:50 pm-10:10 pm
1 stop6h 20m
$155
Panama CityLouisville
ECP - SDF
ECPSDF
Panama City NW Florida Beaches
Sat 9/26
10:30 am-5:30 pm
2 stops6h 00m
$160
Showing 1-10 of 15 resultsSorted by cheapest first
Compare providers for flights from Panama City to Louisville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Louisville in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Panama City, Florida-Louisville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-Louisville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Louisville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City, Florida-Louisville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Louisville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to Louisville
Have a flexible travel schedule? Discover the best time to fly to Louisville from Panama City with our price prediction graph.
ECP-SDF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Louisville
Reviews of airlines servicing Louisville
Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated August 3, 2026.
Read through reviews of airlines operating flights from Panama City to Louisville, such as Southwest and Delta. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Boarding
8.1
Overall
8.0
Entertainment
7.5
Comfort
8.0
Food
7.0
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Crew
8.6
Boarding
8.1
Overall
8.0
Entertainment
7.5
Comfort
8.0
Food
7.0
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Crew
8.6
Boarding
8.1
Overall
8.0
Entertainment
7.5
Comfort
8.0
Food
7.0
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Related info for your journey
Find useful and relevant information for your journey from Panama City to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Louisville?
Book flights to Louisville if you plan to visit one of these locationsCorydon
Shepherdsville
Elizabethtown
Jeffersonville
Bardstown
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Alternative routes for Panama City to Louisville
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Complete your trip
Complete your trip to Louisville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Panama City to Louisville by cabin class
Find flights from Panama City to Louisville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Louisville
Explore flights to Louisville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 3, 2026.
Panama City and Louisville flights
Browse other Panama City and Louisville flight options. Last updated on August 3, 2026.
Other flights from Panama City
Browse through other flights departing from Panama City. Flights are based on user searches made on Cheapflights and were last updated on August 3, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Panama City to Louisville
Discover the top 2 airlines that operate flights from Panama City to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$259 | Average$442 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$302 | Average$456 | FlexibilityNo cancel fee | On-time63% |