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Key West

$222+ Cheap flights from Harrisburg to Key West (MDT - EYW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/11. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — EYW
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheapflights Tip: The best prices from Harrisburg to Key West are usually found in September or November, booked 82 days in advance, depart on a Tuesday or Monday and return on a Monday

Cheap flight deals from Harrisburg to Key West

Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2025.

Round-trip from

$259
(American Airlines)

One-way from

$222
(Kiwi.com)

Popular in

March

Cheapest in

September

Average price

$326
From Harrisburg to Key West
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One-way flight from Harrisburg to Key West
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Highest demand for flights based on searches. 5% potential increase in price ($24 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Harrisburg to Key West

Cheapest flights from Harrisburg to Key West
Explore the most affordable flight options available from Harrisburg to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1212:56 pmMDT - EYW
1 stop4h 56mAmerican Airlines
Tue 12/166:33 pmEYW - MDT
1 stop5h 17mAmerican Airlines
Deal found 9/15$259
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/189:12 pmMDT - EYW
1 stop17h 28mAllegiant Air
Wed 10/2210:02 amEYW - MDT
1 stop10h 14mAllegiant Air
Deal found 9/16$268
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/74:25 pmMDT - EYW
1 stop6h 02mAmerican Airlines
Fri 11/145:09 pmEYW - MDT
1 stop5h 06mAmerican Airlines
Deal found 9/15$274
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/84:25 pmMDT - EYW
1 stop5h 21mAmerican Airlines
Sat 12/138:00 amEYW - MDT
1 stop7h 02mAmerican Airlines
Deal found 9/15$304
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/14:18 pmMDT - EYW
1 stop23h 46mAllegiant Air
Sun 10/53:30 pmEYW - MDT
1 stop28h 05mAllegiant Air
Deal found 9/16$320
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/181:04 pmMDT - EYW
1 stop7h 02mDelta
Wed 10/226:17 pmEYW - MDT
1 stop4h 51mDelta
Deal found 9/16$324

Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Harrisburg to Key West that are best for you.

Fly from

Harrisburg

Fly to

Key West

Route

Depart

Return

Price

HarrisburgKey West

MDT - EYW

MDTEYW

Harrisburg

Sat 12/6

3:48 pm-9:50 pm

1 stop6h 02m

Key West

Fri 12/12

12:46 pm-7:07 pm

1 stop6h 21m

$259

HarrisburgKey West

MDT - EYW

MDTEYW

Harrisburg

Fri 12/12

4:25 pm-10:18 pm

1 stop5h 53m

Key West

Tue 12/16

6:33 pm-11:50 pm

1 stop5h 17m

$259

HarrisburgKey West

MDT - EYW

MDTEYW

Harrisburg

Sat 10/18

9:12 pm-2:40 pm

1 stop17h 28m

Key West

Wed 10/22

10:02 am-8:16 pm

1 stop10h 14m

$268

HarrisburgKey West

MDT - EYW

MDTEYW

Harrisburg

Fri 11/7

4:25 pm-10:27 pm

1 stop6h 02m

Key West

Fri 11/14

4:18 pm-11:53 pm

2 stops7h 35m

$279

HarrisburgKey West

MDT - EYW

MDTEYW

Harrisburg

Thu 12/11

9:30 am-8:15 am

2 stops22h 45m

$222

HarrisburgKey West

MDT - EYW

MDTEYW

Harrisburg

Sun 9/28

12:17 pm-9:07 am

2 stops44h 50m

$245

HarrisburgKey West

MDT - EYW

MDTEYW

Harrisburg

Thu 12/11

3:46 pm-9:45 pm

1 stop5h 59m

$271

HarrisburgKey West

MDT - EYW

MDTEYW

Harrisburg

Thu 11/27

8:15 am-3:19 pm

1 stop7h 04m

$329

HarrisburgKey West

MDT - EYW

MDTEYW

Harrisburg

Sat 9/20

7:30 am-5:46 pm

2 stops10h 16m

$342

HarrisburgKey West

MDT - EYW

MDTEYW

Harrisburg

Thu 11/27

6:00 am-2:03 pm

2 stops8h 03m

$385

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Best time to book a flight from Harrisburg to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Key West

How far ahead should I book a flight from Harrisburg to Key West?

Use this chart to determine the optimal time to book a round-trip flight from Harrisburg to Key West. Price data was last updated on September 12, 2025.

To ensure you get the cheapest price possible for a flight from Harrisburg to Key West, you should look to book at least 54 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Harrisburg to Key West?

Currently, August is the cheapest month in which you can book a flight from Harrisburg to Key West (average of $328). Flying from Harrisburg to Key West in March is currently the most expensive (average of $491). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Harrisburg to Key West?

Reviews of airlines servicing Key West

Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated September 17, 2025.
Read reviews from past customers who have flown Delta and American Airlines from Harrisburg to Key West. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Delta
8.0
Very good
7,961 reviews
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Harrisburg to Key West?

    For as low as $259, American Airlines can have you in Key West from Harrisburg in 6h 02m. There are 1118 mi between Harrisburg and Key West.

  • What are the cheapest airlines flying from Harrisburg to Key West round-trip?

    Flying on Delta is currently your cheapest option to Key West, with prices starting at $258. Another option worth looking into is American Airlines, starting at $259 round trip. You may be able to fly from Harrisburg to Key West for 42% less than the average price by searching for these airlines.

  • Can I find deals for flights from Harrisburg to Key West that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Key West.

  • Can I find deals for business class flights from Harrisburg to Key West?

    Yes. Cheapflights offers flight deals from Harrisburg to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to Key West?

    Currently, August is the cheapest month in which you can book a flight from Harrisburg to Key West (average of $328). Flying from Harrisburg to Key West in March is currently the most expensive (average of $491). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Harrisburg to Key West

Discover the top 2 airlines that operate flights from Harrisburg to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$258Average$513FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$259Average$448FlexibilityNo cancel feeOn-time71%

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