HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Key West

$110+ Cheap flights from Columbia to Key West (CAE - EYW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/30. Fares are subject to change and may not be available on all flights or dates of travel.
CAE — EYW
oct. 17 — oct. 241
ven. 10/17
ven. 10/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Columbia to Key West with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Columbia to Key West

Discover tips and strategies to find the most affordable flight options for your journey from Columbia (CAE) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septembre 17, 2025.

Round-trip from

$299
(Delta)

One-way from

$110
(Kiwi.com)

Popular in

April

Cheapest in

November

Average price

$465
From Columbia Metropolitan to Key West
Search Deals
One-way flight from Columbia Metropolitan to Key West
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($49 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from Columbia to Key West

Cheapest flights from Columbia to Key West
Explore the most affordable flight options available from Columbia to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septembre 17, 2025.

This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/131:15 pmCAE - EYW
1 stop6h 51mDelta
lun. 10/207:40 amEYW - CAE
1 stop6h 38mDelta
Deal found 9/15$299
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 12/1012:15 pmCAE - EYW
1 stop5h 37mAmerican Airlines
sam. 12/134:20 pmEYW - CAE
2 stops7h 36mAmerican Airlines
Deal found 9/14$341
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/3011:02 amCAE - EYW
1 stop6h 13mDelta
sam. 10/47:00 amEYW - CAE
1 stop5h 12mDelta
Deal found 9/15$414
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 10/237:30 pmCAE - EYW
1 stop17h 28mAmerican Airlines
lun. 11/35:31 pmEYW - CAE
1 stop16h 28mAmerican Airlines
Deal found 9/15$457
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/3010:15 amCAE - EYW
2 stops8h 44mAmerican Airlines
sam. 10/46:17 pmEYW - CAE
1 stop4h 50mAmerican Airlines
Deal found 9/15$498
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 9/191:22 pmCAE - EYW
1 stop6h 45mDelta
mar. 9/236:10 pmEYW - CAE
1 stop5h 27mDelta
Deal found 9/15$518
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 12/196:16 pmCAE - EYW
1 stop4h 28mAmerican Airlines
jeu. 12/258:00 amEYW - CAE
1 stop6h 10mAmerican Airlines
Deal found 9/16$532

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbia to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septembre 17, 2025.
Use the filters below to find and compare flights from Columbia to Key West that are best for you.

Fly from

Columbia

Fly to

Key West

Route

Depart

Return

Price

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

lun. 10/13

1:15 pm-8:06 pm

1 stop6h 51m

Key West

lun. 10/20

7:40 am-2:18 pm

1 stop6h 38m

$299

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

mer. 12/10

12:15 pm-5:52 pm

1 stop5h 37m

Key West

sam. 12/13

4:20 pm-11:56 pm

2 stops7h 36m

$341

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

mar. 9/30

11:02 am-5:15 pm

1 stop6h 13m

Key West

sam. 10/4

7:00 am-12:12 pm

1 stop5h 12m

$414

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

mar. 9/30

10:15 am-6:59 pm

2 stops8h 44m

Key West

sam. 10/4

6:17 pm-11:07 pm

1 stop4h 50m

$498

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

jeu. 10/2

1:22 pm-8:07 pm

1 stop6h 45m

Key West

lun. 10/6

7:40 am-12:30 pm

1 stop4h 50m

$548

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

jeu. 10/30

4:33 pm-8:15 am

1 stop15h 42m

$110

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Best time to book a flight from Columbia to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from Columbia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbia to Key West

What is the cheapest month to book a flight from Columbia to Key West?

Currently, August is the cheapest month in which you can book a flight from Columbia to Key West (average of $328). Flying from Columbia to Key West in March is currently the most expensive (average of $491). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Key West

Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated septembre 17, 2025.
Peruse reviews from past customers who have flown with Delta and American Airlines from Columbia to Key West to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,961 reviews

Boarding

8.2

Crew

8.5

Overall

8.0

Food

7.3

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

CAE - ATL

On time flights; courteous staff; efficient boarding system! Thank you!
Delta
8.0
Very good
7,961 reviews
Delta
8.0
Very good
7,961 reviews

Boarding

8.2

Crew

8.5

Overall

8.0

Food

7.3

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

CAE - ATL

On time flights; courteous staff; efficient boarding system! Thank you!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,961 reviews

Boarding

8.2

Crew

8.5

Overall

8.0

Food

7.3

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

CAE - ATL

On time flights; courteous staff; efficient boarding system! Thank you!

Related info for your journey

Find useful and relevant information for your journey from Columbia to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Columbia to Key West?

    For as low as $341, Delta can have you in Key West from Columbia in 5h 37m. The distance between Columbia and Key West is about 649 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Columbia to Key West round-trip?

    According to our current data, Delta ($248), and American Airlines ($331) offers the cheapest pricing from Columbia to Key West. Delta is priced at 50% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Columbia to Key West that include hotel bookings?

    Yes. In addition to deals on Columbia to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbia to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbia to Key West.

  • Can I find deals for business class flights from Columbia to Key West?

    Yes. Cheapflights offers flight deals from Columbia to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbia to Key West?

    Currently, August is the cheapest month in which you can book a flight from Columbia to Key West (average of $328). Flying from Columbia to Key West in March is currently the most expensive (average of $491). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Columbia to Key West

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to Miami flights
Charlotte to Fort Lauderdale flights
Charlotte to Orlando flights
Charlotte to Tampa flights
Charleston to Fort Lauderdale flights
Charleston to Miami flights
Charlotte to Fort Myers flights
Charlotte to Jacksonville flights
Myrtle Beach to Fort Lauderdale flights
Charlotte to West Palm Beach flights
Charlotte to Sarasota flights
Greenville to Miami flights
Charleston to Orlando flights
Charlotte to Key West flights
Myrtle Beach to Orlando flights
Columbia to Miami flights
Myrtle Beach to Miami flights
Columbia to Orlando flights
Savannah to Miami flights
Charlotte to Tallahassee flights
Charleston to Tampa flights
Greenville to Orlando flights
Columbia to Tampa flights
Charlotte to Valparaiso flights
Greenville to Fort Lauderdale flights
Columbia to West Palm Beach flights
Columbia to Fort Lauderdale flights
Charlotte to Pensacola flights
Charleston to Key West flights
Charlotte to Panama City flights
Greenville to Fort Myers flights
Charlotte to Daytona Beach flights
Greenville to Orlando Sanford Intl flights
Charleston to West Palm Beach flights
Savannah to Fort Lauderdale flights
Greenville to Tampa flights
Greenville to Jacksonville flights
Myrtle Beach to West Palm Beach flights
Myrtle Beach to Tampa flights
Greenville to West Palm Beach flights
Charlotte to Melbourne flights
Myrtle Beach to Fort Myers flights
Savannah to Key West flights
Augusta to Fort Lauderdale flights
Greenville to Sarasota flights
Columbia to Sarasota flights
Myrtle Beach to Key West flights
Greenville to Valparaiso flights
Charleston to Pensacola flights
Augusta to Miami flights

Top 2 airlines flying from Columbia to Key West

Discover the top 2 airlines that operate flights from Columbia to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septembre 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$248Average$490FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$331Average$548FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.