$150+ Cheap flights from Medford (MFR) to Key Largo, FL
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/3. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — MIA
Jun 23 — Jun 301
Round-trip
1 adult, Economy
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Find cheap flights from Medford to Key Largo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Best
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One-way
Cheapest flights from Medford to Key LargoExplore the most affordable flight options available from Medford to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 24, 2026.
Explore the most affordable flight options available from Medford to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 24, 2026.
This Expedia deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/167:50 pm
MFR
- MIA
1 stop18h 27m
Alaska Airlines
Wed 8/196:22 pm
MIA
- MFR
1 stop18h 29m
Alaska Airlines
Deal found 5/21![Alaska Airlines logo]()
$299
This Delta deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/15:21 pm
MFR
- MIA
2 stops9h 47m
Delta
Sat 11/146:50 am
MIA
- MFR
1 stop8h 46m
Delta
Deal found 5/22![Delta logo]()
$304
This Expedia deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:11 am
MFR
- MIA
2 stops12h 54m
Alaska Airlines
Wed 8/56:20 pm
MIA
- MFR
1 stop8h 44m
Alaska Airlines
Deal found 5/22![Alaska Airlines logo]()
$354
This Travelocity deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/167:50 pm
MFR
- MIA
1 stop18h 27m
Alaska Airlines
Fri 8/218:30 pm
MIA
- MFR
1 stop29h 05m
Alaska Airlines
Deal found 5/23![Alaska Airlines logo]()
$360
This Alaska Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:00 am
MFR
- MIA
1 stop8h 13m
Alaska Airlines
Wed 9/306:16 pm
MIA
- MFR
1 stop8h 43m
Alaska Airlines
Deal found 5/20![Alaska Airlines logo]()
$364
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/319:11 pm
MFR
- MIA
1 stop30h 19m
Multiple Airlines
Wed 8/1210:15 pm
MIA
- MFR
1 stop25h 33m
Multiple Airlines
Deal found 5/20![Multiple Airlines logo]()
$380
This Delta deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1612:20 pm
MFR
- MIA
2 stops14h 25m
Delta
Mon 7/272:42 pm
MIA
- MFR
2 stops11h 29m
Delta
Deal found 5/20![Delta logo]()
$399
Best flights from Medford to Key LargoDiscover carefully curated flight deals from Medford to Key Largo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 24, 2026.
Discover carefully curated flight deals from Medford to Key Largo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 24, 2026.
This Delta deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/112:25 pm
MFR
- MIA
2 stops14h 17m
Delta
Wed 7/84:00 pm
MIA
- MFR
2 stops10h 54m
Delta
Deal found 5/24![Delta logo]()
$419
This Alaska Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:00 am
MFR
- MIA
1 stop8h 13m
Alaska Airlines
Wed 9/3011:25 am
MIA
- MFR
2 stops15h 34m
Alaska Airlines
Deal found 5/20![Alaska Airlines logo]()
$469
This United Airlines deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:35 pm
MFR
- MIA
1 stop10h 04m
United Airlines
Thu 6/186:35 pm
MIA
- MFR
1 stop31h 24m
United Airlines
Deal found 5/23![United Airlines logo]()
$603
This Delta deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:05 am
MFR
- MIA
1 stop8h 22m
Delta
Sat 11/146:50 am
MIA
- MFR
1 stop8h 46m
Delta
Deal found 5/23![Delta logo]()
$419
This Delta deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1612:20 pm
MFR
- MIA
2 stops14h 25m
Delta
Mon 7/272:42 pm
MIA
- MFR
2 stops11h 29m
Delta
Deal found 5/19![Delta logo]()
$420
This Delta deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1412:22 pm
MFR
- MIA
2 stops14h 31m
Delta
Mon 9/217:10 am
MIA
- MFR
1 stop7h 32m
Delta
Deal found 5/23![Delta logo]()
$424
This Alaska Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/97:50 pm
MFR
- MIA
1 stop18h 27m
Alaska Airlines
Fri 8/142:20 pm
MIA
- MFR
2 stops12h 44m
Alaska Airlines
Deal found 5/24![Alaska Airlines logo]()
$524
This Alaska Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/165:58 am
MFR
- MIA
1 stop8h 19m
Alaska Airlines
Mon 7/276:20 pm
MIA
- MFR
1 stop8h 44m
Alaska Airlines
Deal found 5/21![Alaska Airlines logo]()
$599
This Alaska Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/11:27 pm
MFR
- MIA
1 stop24h 50m
Alaska Airlines
Wed 7/86:20 pm
MIA
- MFR
1 stop8h 44m
Alaska Airlines
Deal found 5/22![Alaska Airlines logo]()
$614
This Delta deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/175:25 pm
MFR
- MIA
2 stops14h 31m
Delta
Thu 6/256:30 am
MIA
- MFR
1 stop13h 14m
Delta
Deal found 5/21![Delta logo]()
$617
Last-minute flights from Medford to Key LargoDiscover last-minute flight deals from Medford to Key Largo. Data last updated May 24, 2026 and is based on user searches.
Discover last-minute flight deals from Medford to Key Largo. Data last updated May 24, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2312:21 pm
MFR
- MIA
2 stops14h 24m
Delta
Tue 5/266:05 pm
MIA
- MFR
1 stop8h 50m
Delta
Deal found 5/22![Delta logo]()
$472
This Expedia deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:45 am
MFR
- MIA
1 stop8h 15m
Alaska Airlines
Tue 5/266:00 pm
MIA
- MFR
1 stop8h 59m
Alaska Airlines
Deal found 5/22![Alaska Airlines logo]()
$502
This Delta deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/245:15 am
MFR
- MIA
2 stops14h 56m
Delta
Wed 5/276:05 pm
MIA
- MFR
1 stop8h 50m
Delta
Deal found 5/22![Delta logo]()
$408
This Alaska Airlines deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/245:45 am
MFR
- MIA
1 stop8h 15m
Alaska Airlines
Wed 5/276:00 pm
MIA
- MFR
1 stop8h 59m
Alaska Airlines
Deal found 5/23![Alaska Airlines logo]()
$485
This Delta deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:15 am
MFR
- MIA
2 stops15h 32m
Delta
Fri 5/296:05 pm
MIA
- MFR
1 stop8h 50m
Delta
Deal found 5/23![Delta logo]()
$481
This Orbitz deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/271:26 pm
MFR
- MIA
1 stop24h 34m
Alaska Airlines
Fri 5/296:00 pm
MIA
- MFR
1 stop8h 59m
Alaska Airlines
Deal found 5/22![Alaska Airlines logo]()
$483
This Delta deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/296:01 am
MFR
- MIA
1 stop8h 30m
Delta
Mon 7/66:30 am
MIA
- MFR
1 stop9h 31m
Delta
Deal found 5/24![Delta logo]()
$403
One-way flights from Medford to Key LargoSearch for one-way flight options from Medford to Key Largo. Find affordable one-way fares based on user searches. Data last updated May 24, 2026.
Search for one-way flight options from Medford to Key Largo. Find affordable one-way fares based on user searches. Data last updated May 24, 2026.
This Delta deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:05 am
MFR
- MIA
1 stop8h 22m
Delta
Deal found 5/21![Delta logo]()
$150
This Delta deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:05 am
MFR
- MIA
2 stops14h 10m
Delta
Deal found 5/22![Delta logo]()
$155
This Alaska Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:00 am
MFR
- MIA
1 stop8h 13m
Alaska Airlines
Deal found 5/24![Alaska Airlines logo]()
$329
This United Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/195:00 am
MFR
- MIA
1 stop7h 56m
United Airlines
Deal found 5/24![United Airlines logo]()
$330
This Delta deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:05 am
MFR
- MIA
1 stop8h 22m
Delta
Deal found 5/24![Delta logo]()
$340
This Delta deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:01 am
MFR
- MIA
1 stop8h 30m
Delta
Deal found 5/22![Delta logo]()
$400
This United Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/182:07 pm
MFR
- MIA
3 stops22h 48m
United Airlines
Deal found 5/24![United Airlines logo]()
$484
This United Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:35 pm
MFR
- MIA
2 stops18h 41m
United Airlines
Deal found 5/22![United Airlines logo]()
$538
Find flight deals from Medford to Key Largo
Keep the following information in mind while searching for Medford to Key Largo flight deals. Data was last updated May 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $299 (Expedia) |
One-way from | $150 (Delta) |
Popular in | December |
Cheapest in | June |
Average price | $574 |
Cheapflights Fare Finder
Customize your flight search to find flights from Medford to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 24, 2026.
Use the filters below to find and compare flights from Medford to Key Largo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MedfordMiami
MFR - MIA
MFRMIA
Medford
Wed 7/1
12:25 pm-5:42 am
2 stops14h 17m
Miami
Wed 7/8
4:00 pm-11:54 pm
2 stops10h 54m
$419
MedfordMiami
MFR - MIA
MFRMIA
Medford
Sun 11/1
6:05 am-5:27 pm
1 stop8h 22m
Miami
Sat 11/14
6:50 am-12:36 pm
1 stop8h 46m
$419
MedfordMiami
MFR - MIA
MFRMIA
Medford
Thu 7/16
12:20 pm-5:45 am
2 stops14h 25m
Miami
Mon 7/27
2:42 pm-11:11 pm
2 stops11h 29m
$420
MedfordMiami
MFR - MIA
MFRMIA
Medford
Mon 9/14
12:22 pm-5:53 am
2 stops14h 31m
Miami
Mon 9/21
7:10 am-11:42 am
1 stop7h 32m
$424
MedfordMiami
MFR - MIA
MFRMIA
Medford
Mon 9/28
6:00 am-5:13 pm
1 stop8h 13m
Miami
Wed 9/30
11:25 am-11:59 pm
2 stops15h 34m
$469
MedfordMiami
MFR - MIA
MFRMIA
Medford
Sun 8/9
7:50 pm-5:17 pm
1 stop18h 27m
Miami
Fri 8/14
2:20 pm-12:04 am
2 stops12h 44m
$524
Quickest round-trip
MedfordMiami
MFR - MIA
MFRMIA
Medford
Thu 7/16
5:58 am-5:17 pm
1 stop8h 19m
Miami
Mon 7/27
6:20 pm-12:04 am
1 stop8h 44m
$599
MedfordMiami
MFR - MIA
MFRMIA
Medford
Wed 6/10
6:35 pm-7:39 am
1 stop10h 04m
Miami
Thu 6/18
6:35 pm-10:59 pm
1 stop31h 24m
$603
MedfordMiami
MFR - MIA
MFRMIA
Medford
Wed 7/1
1:27 pm-5:17 pm
1 stop24h 50m
Miami
Wed 7/8
6:20 pm-12:04 am
1 stop8h 44m
$614
MedfordMiami
MFR - MIA
MFRMIA
Medford
Wed 6/17
5:25 pm-10:56 am
2 stops14h 31m
Miami
Thu 6/25
6:30 am-4:44 pm
1 stop13h 14m
$617
Showing 1-10 of 17 resultsSorted by cheapest first
Best time to book a flight from Medford to Key Largo
Have a flexible travel schedule? Discover the best time to fly to Key Largo from Medford with our price prediction graph.
MFR-MIA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Medford to Key Largo
MFR-KE9
MFR-MIA
How much does it cost to fly round-trip from Medford to Key Largo?
Reviews of airlines servicing Key Largo
Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated May 24, 2026.
See what other customers who have flown with Alaska Airlines,United Airlines, andAmerican Airlines from Medford to Key Largo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.0
Overall
7.9
Reviews
1 / 20
8.0
ExcellentEugene,Mar 2026
MFR - SEA
Food
7.0
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.0
Overall
7.9
Reviews
1 / 20
8.0
ExcellentEugene,Mar 2026
MFR - SEA
Food
7.0
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.0
Overall
7.9
Reviews
1 / 20
8.0
ExcellentEugene,Mar 2026
MFR - SEA
Food
7.0
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.0
Overall
7.9
Reviews
1 / 20
8.0
ExcellentEugene,Mar 2026
MFR - SEA
Related info for your journey
Find useful and relevant information for your journey from Medford to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
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Find flights from Medford to Key Largo, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Medford and Key Largo flights
Browse other Medford and Key Largo flight options. Last updated on May 24, 2026.
Other flights from Medford
Browse through other flights departing from Medford. Flights are based on user searches made on Cheapflights and were last updated on May 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Medford to Key Largo flights
Consider these flights traveling from Medford to Key Largo.
Top 4 airlines flying from Medford to Key Largo
Discover the top 4 airlines that operate flights from Medford to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$166 | Average$384 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$286 | Average$473 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$344 | Average$582 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$402 | Average$568 | FlexibilityNo cancel fee | On-time71% |