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Key Largo

$68+ Cheap flights from Iowa to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/22. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MIA
Jan 27 — Feb 31
Tue 1/27
Tue 2/3
1 adult, Economy
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Cheap flight deals from Iowa to Key Largo

Cheapest flights from Iowa to Key Largo
Explore the most affordable flight options available from Iowa to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

This American Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/311:58 pmOMA - MIA
1 stop5h 36mAmerican Airlines
Tue 1/139:00 pmMIA - OMA
Nonstop3h 59mAmerican Airlines
Deal found 12/26$363
This Southwest deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:45 pmOMA - MIA
1 stop6h 05mSouthwest
Wed 1/77:55 amMIA - OMA
1 stop7h 35mSouthwest
Deal found 12/26$373
This Southwest deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:45 amOMA - MIA
2 stops12h 00mSouthwest
Tue 1/132:00 pmMIA - OMA
1 stop8h 00mSouthwest
Deal found 12/26$378
This Southwest deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:20 amDSM - MIA
1 stop6h 40mSouthwest
Wed 1/74:55 pmMIA - DSM
1 stop5h 15mSouthwest
Deal found 12/26$393
This Frontier deal was found by Cheapflights users on 12/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/294:35 pmOMA - MIA
1 stop7h 16mFrontier
Mon 1/55:30 amMIA - OMA
1 stop11h 10mFrontier
Deal found 12/24$403
This Southwest deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/293:15 pmOMA - MIA
1 stop7h 50mSouthwest
Sat 1/106:45 amMIA - OMA
1 stop8h 10mSouthwest
Deal found 12/27$420
This Expedia deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/294:35 pmOMA - MIA
1 stop7h 16mFrontier
Fri 1/25:30 amMIA - OMA
1 stop11h 05mFrontier
Deal found 12/25$432
This American Airlines deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/296:20 amMLI - MIA
1 stop7h 02mAmerican Airlines
Tue 1/66:37 amMIA - MLI
1 stop5h 21mAmerican Airlines
Deal found 12/25$439
This American Airlines deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/296:00 amOMA - MIA
Nonstop3h 42mAmerican Airlines
Sat 1/108:35 amMIA - OMA
1 stop9h 15mAmerican Airlines
Deal found 12/27$442
This Delta deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:22 pmOMA - MIA
1 stop5h 26mDelta
Thu 1/18:45 amMIA - OMA
1 stop6h 38mDelta
Deal found 12/26$452
This Southwest deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2811:55 amOMA - MIA
1 stop6h 30mSouthwest
Wed 12/316:55 amMIA - OMA
2 stops9h 40mSouthwest
Deal found 12/26$457
This Southwest deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:30 amDSM - MIA
2 stops16h 25mSouthwest
Tue 1/64:55 pmMIA - DSM
1 stop5h 15mSouthwest
Deal found 12/25$473

Find flight deals from Iowa to Key Largo

Keep the following information in mind while searching for Iowa to Key Largo flight deals. Data was last updated December 28, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$166
(Kiwi.com)

One-way from

$68
(Trip.com)

Popular in

March

Cheapest in

June

Average price

$357
Provider with most accurate pricing for Des Moines-Miami flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Miami flights.
Search Deals
From Iowa to Key Largo
Search Deals
One-way flight from Iowa to Key Largo
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($51 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
Use the filters below to find and compare flights from Iowa to Key Largo that are best for you.

Fly from

Iowa

Fly to

Key Largo

Route

Depart

Return

Price

OmahaMiami

OMA - MIA

OMAMIA

Omaha Eppley Airfield

Sat 2/21

4:20 pm-10:30 pm

1 stop5h 10m

Miami

Sat 2/28

6:35 am-1:30 pm

2 stops7h 55m

$221

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Sat 1/31

5:45 am-3:35 pm

1 stop8h 50m

Miami

Wed 2/4

12:00 pm-9:10 pm

2 stops10h 10m

$223

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Sat 1/24

10:15 am-7:04 pm

1 stop7h 49m

Miami

Sat 1/31

5:50 am-12:15 pm

1 stop7h 25m

$237

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Sat 1/31

7:50 am-8:29 pm

2 stops11h 39m

Miami

Tue 2/3

9:05 am-2:22 pm

1 stop6h 17m

$242

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Sat 5/9

1:50 pm-11:01 pm

1 stop8h 11m

Miami

Sat 5/16

5:05 am-11:10 am

1 stop7h 05m

$257

OmahaMiami

OMA - MIA

OMAMIA

Omaha Eppley Airfield

Wed 1/28

6:06 pm-12:51 am

1 stop5h 45m

Miami

Tue 2/10

5:50 am-10:05 am

1 stop5h 15m

$257

OmahaMiami

OMA - MIA

OMAMIA

Omaha Eppley Airfield

Sat 1/24

3:50 pm-9:35 pm

1 stop4h 45m

Miami

Sat 1/31

6:45 am-1:55 pm

1 stop8h 10m

$257

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Tue 6/2

2:35 pm-11:15 pm

1 stop7h 40m

Miami

Tue 6/9

7:15 am-2:07 pm

1 stop7h 52m

$257

OmahaMiami

OMA - MIA

OMAMIA

Omaha Eppley Airfield

Sat 4/4

8:15 am-3:47 pm

1 stop6h 32m

Miami

Sat 4/11

6:15 am-4:20 pm

2 stops11h 05m

$262

OmahaMiami

OMA - MIA

OMAMIA

Omaha Eppley Airfield

Wed 2/18

10:55 am-9:00 pm

2 stops9h 05m

Miami

Wed 2/25

2:00 pm-9:00 pm

1 stop8h 00m

$262

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/26

Showing 1-10 of 60 results
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Best time to book a flight from Iowa to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Key Largo

What is the cheapest month to book a flight from Iowa to Key Largo?

Currently, August is the cheapest month in which you can book a flight from Iowa to Key Largo (average of $66). Flying from Iowa to Key Largo in September is currently the most expensive (average of $205). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to KE9?

Find hourly flight availability from Iowa to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 28, 2025.

When flying from Iowa to Key Largo, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 46% versus a flight in the morning.

Weekly flight availability from Iowa to Key Largo

Explore weekly flight availability from Iowa to Key Largo. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated December 28, 2025.

The most flights from USIA to KE9 are scheduled on a Monday (2 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (2 on average).

Related info for your journey

Find useful and relevant information for your journey from Iowa to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Iowa to Key Largo?

    Airlines like Southwest, Delta, and United Airlines fly from Iowa to Key Largo in about 5h 10m. The time it takes to get you to your destination can typically vary by up to 6h 29m. Iowa and Key Largo are separated by a distance of 1393 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Iowa to Key Largo?

    The most popular flight routes from Iowa to Key Largo are Omaha Eppley Airfield - Miami, Des Moines - Miami and Cedar Rapids - Miami.

  • What are the most reliable airlines from Iowa to Key Largo?

    Before booking your flight to Key Largo from Iowa, check out the most reliable airlines to get you to your destination on time: American Airlines (76%), Envoy Air (76%), Qatar Airways( 74%).

  • What are the cheapest flights from Iowa to Key Largo?

    The cheapest flight price from Iowa to Key Largo is $235. On average you can expect to pay $510. The most popular route, (Omaha Eppley Airfield - Miami), can usually be booked for $216.

  • Can I find deals for flights from Iowa to Key Largo that include hotel bookings?

    Yes. In addition to deals on Iowa to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Key Largo.

  • Can I find deals for business class flights from Iowa to Key Largo?

    Yes. Cheapflights offers flight deals from Iowa to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Key Largo?

    Currently, August is the cheapest month in which you can book a flight from Iowa to Key Largo (average of $66). Flying from Iowa to Key Largo in September is currently the most expensive (average of $205). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Iowa to Key Largo

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Iowa to Key Largo

Discover the top 6 airlines that operate flights from Iowa to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$75Average$162FlexibilityNo cancel feeOn-time88%
FrontierCheapest$109Average$244FlexibilityNo cancel feeOn-time62%
DeltaCheapest$203Average$378FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$226Average$468FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$228Average$441FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$259Average$446FlexibilityNo cancel feeOn-time71%

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