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Key Largo

$64+ Cheap flights from Iowa to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/8. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MIA
Dec 3 — Dec 101
Wed 12/3
Wed 12/10
1 adult, Economy
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Find flight deals from Iowa to Key Largo

Cheapest flights from Iowa to Key Largo
Explore the most affordable flight options available from Iowa to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 3, 2025.

This Frontier deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/168:26 pmCID - MIA
1 stop8h 53mFrontier
Thu 11/208:36 amMIA - CID
1 stop12h 10mFrontier
Deal found 11/2$138
This Frontier deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/55:50 pmOMA - MIA
1 stop5h 56mFrontier
Mon 12/85:30 amMIA - OMA
1 stop10h 58mFrontier
Deal found 11/1$142
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/144:21 pmDSM - MIA
1 stop7h 34mMultiple Airlines
Sun 1/117:35 amMIA - DSM
1 stop15h 34mMultiple Airlines
Deal found 11/2$175
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/26:15 amDSM - MIA
1 stop5h 10mSouthwest
Tue 12/91:45 pmMIA - DSM
1 stop7h 10mSouthwest
Deal found 11/2$179
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/42:24 pmOMA - MIA
1 stop13h 55mFrontier
Wed 12/105:58 pmMIA - OMA
2 stops44h 33mFrontier
Deal found 11/1$207
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/23:21 pmDSM - MIA
1 stop7h 19mAmerican Airlines
Tue 12/98:50 pmMIA - DSM
Nonstop3h 39mAmerican Airlines
Deal found 11/2$208
This Frontier deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/18:36 pmOMA - MIA
1 stop7h 34mFrontier
Fri 12/55:30 amMIA - OMA
1 stop11h 58mFrontier
Deal found 11/2$210
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/32:16 pmDSM - MIA
1 stop5h 35mDelta
Fri 12/121:31 pmMIA - DSM
1 stop7h 12mDelta
Deal found 11/1$217
This Southwest deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/156:15 amDSM - MIA
1 stop5h 10mSouthwest
Sat 12/207:50 pmMIA - DSM
1 stop5h 05mSouthwest
Deal found 10/31$218
This Frontier deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/57:58 pmDSM - MIA
1 stop8h 21mFrontier
Fri 12/126:00 amMIA - DSM
1 stop14h 03mFrontier
Deal found 11/1$219
This Priceline deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/55:50 pmOMA - MIA
1 stop5h 56mFrontier
Sun 12/76:00 amMIA - OMA
1 stop8h 31mFrontier
Deal found 11/1$220
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/42:56 pmDSM - MIA
2 stops26h 51mMultiple Airlines
Fri 12/126:00 amMIA - DSM
1 stop14h 03mMultiple Airlines
Deal found 11/1$222

Cheap flight deals from Iowa to Key Largo

Keep the following information in mind while searching for Iowa to Key Largo flight deals. Data was last updated November 3, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$130
(Frontier)

One-way from

$64
(Trip.com)

Popular in

March

Cheapest in

June

Average price

$413
Provider with most accurate pricing for Des Moines-Miami flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Miami flights.
Search Deals
From Iowa to Key Largo
Search Deals
One-way flight from Iowa to Key Largo
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($50 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from Iowa to Key Largo that are best for you.

Fly from

Iowa

Fly to

Key Largo

Route

Depart

Return

Price

Cedar RapidsMiami

CID - MIA

CIDMIA

Cedar Rapids

Sun 11/16

8:26 pm-6:19 am

1 stop8h 53m

Miami

Thu 11/20

8:36 am-7:46 pm

1 stop12h 10m

$138

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Tue 12/2

6:15 am-12:25 pm

1 stop5h 10m

Miami

Tue 12/9

1:45 pm-7:55 pm

1 stop7h 10m

$179

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Wed 12/3

2:16 pm-8:51 pm

1 stop5h 35m

Miami

Fri 12/12

1:31 pm-7:43 pm

1 stop7h 12m

$217

OmahaMiami

OMA - MIA

OMAMIA

Omaha Eppley Airfield

Sat 1/17

3:00 pm-10:35 pm

1 stop6h 35m

Miami

Sat 1/24

7:15 am-4:14 pm

1 stop9h 59m

$257

OmahaMiami

OMA - MIA

OMAMIA

Omaha Eppley Airfield

Wed 12/3

1:25 pm-8:25 pm

1 stop6h 00m

Miami

Sat 12/6

5:05 pm-9:45 pm

1 stop5h 40m

$257

OmahaMiami

OMA - MIA

OMAMIA

Omaha Eppley Airfield

Wed 2/11

6:06 pm-12:51 am

1 stop5h 45m

Miami

Wed 2/25

10:20 am-5:51 pm

1 stop8h 31m

$257

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Fri 12/5

6:33 pm-12:46 am

1 stop5h 13m

Miami

Fri 12/12

6:00 am-10:38 am

1 stop5h 38m

$259

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Fri 12/5

6:33 pm-12:46 am

1 stop5h 13m

Miami

Sat 12/13

8:05 am-2:12 pm

1 stop7h 07m

$259

MolineMiami

MLI - MIA

MLIMIA

Moline Quad-City

Wed 1/21

6:15 am-12:48 pm

1 stop5h 33m

Miami

Sun 2/1

6:37 am-10:58 am

1 stop5h 21m

$264

OmahaMiami

OMA - MIA

OMAMIA

Omaha Eppley Airfield

Thu 11/13

7:46 pm-6:19 am

1 stop9h 33m

Miami

Mon 11/17

6:00 am-8:06 pm

1 stop15h 06m

$265

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/1

Showing 1-10 of 60 results
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Best time to book a flight from Iowa to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Key Largo

What is the cheapest month to book a flight from Iowa to Key Largo?

Currently, August is the cheapest month in which you can book a flight from Iowa to Key Largo (average of $67). Flying from Iowa to Key Largo in September is currently the most expensive (average of $204). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to KE9?

Find hourly flight availability from Iowa to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 3, 2025.

When flying from Iowa to Key Largo, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 46% versus a flight in the morning.

What is the cheapest day to fly from Iowa to Key Largo?

Use this chart to determine the cheapest time to fly round-trip from Iowa to Key Largo. Price data was last updated on November 24, 2024.

Travelers seeking maximum savings on their Iowa to Key Largo flight should consider departing on Thursday mornings when fares are most often at their lowest. Wednesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Iowa to Key Largo

Explore weekly flight availability from Iowa to Key Largo. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated November 3, 2025.

The most flights from USIA to KE9 are scheduled on a Monday (2 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (2 on average).

How much does it cost to fly round-trip from Iowa to Key Largo?

Related info for your journey

Find useful and relevant information for your journey from Iowa to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Iowa to Key Largo?

    Airlines like Frontier, Southwest, and Delta fly from Iowa to Key Largo in about 5h 10m. The time it takes to get you to your destination can typically vary by up to 3h 43m. Iowa and Key Largo are separated by a distance of 1328 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Iowa to Key Largo one-way?

    The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $73. However, be on the lookout for offers from Southwest and Delta, as they are both options that can get you from Iowa to Key Largo for a low price.

  • What are the most popular routes from Iowa to Key Largo?

    The most popular flight routes from Iowa to Key Largo are Des Moines - Miami, Omaha Eppley Airfield - Miami and Cedar Rapids - Miami.

  • What are the cheapest flights from Iowa to Key Largo?

    The cheapest flight price from Iowa to Key Largo is $146. On average you can expect to pay $464. The most popular route, (Des Moines - Miami), can usually be booked for $175.

  • Can I find deals for flights from Iowa to Key Largo that include hotel bookings?

    Yes. In addition to deals on Iowa to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Key Largo.

  • Can I find deals for business class flights from Iowa to Key Largo?

    Yes. Cheapflights offers flight deals from Iowa to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Key Largo?

    Currently, August is the cheapest month in which you can book a flight from Iowa to Key Largo (average of $67). Flying from Iowa to Key Largo in September is currently the most expensive (average of $204). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 6 airlines flying from Iowa to Key Largo

Discover the top 6 airlines that operate flights from Iowa to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$76Average$176FlexibilityNo cancel feeOn-time88%
FrontierCheapest$109Average$244FlexibilityNo cancel feeOn-time62%
DeltaCheapest$216Average$372FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$226Average$454FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$228Average$456FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$258Average$446FlexibilityNo cancel feeOn-time71%

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