How popular is this St. Louis to Jacksonville flight route?

Flights from Lambert-St Louis to Jacksonville have been viewed 6 times in the past calendar month.

How long is the flight from St. Louis to Jacksonville?

Southwest and Delta can get you from St. Louis to Jacksonville in just under 4h 35m. Your travel time can differ by up to 1h 26m. Airlines will cover a distance of 753 mi. This flight may include one or multiple stops.

What are the cheapest airlines flying from St. Louis to Jacksonville round-trip?

According to our current data, American Airlines ($186), Delta ($202), and Southwest ($214) offers the cheapest pricing from St. Louis to Jacksonville. You may be able to fly from St. Louis to Jacksonville for 40% less than the average price by searching for these airlines.

What are the cheapest airlines to fly from St. Louis to Jacksonville one-way?

For one-way options, check prices for Delta. According to our data, you can fly for as low as $66. Users have also found prices from $94 and $109 on Southwest and American Airlines, respectively.

In terms of precipitation, rainfall in Jacksonville ranges from 2.1 - 8.2 inches per month. September is typically the wettest month, when rainfall can reach 8.2 in. November is typically the driest time to visit Jacksonville when rainfall is around 2.1 in.

If weather is an important factor for your trip to Jacksonville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 82.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 53.6 F).

What are the cheapest flights from St. Louis to Jacksonville?

Looking for the cheapest flight from St. Louis to Jacksonville? While on average our users pay $394, our data indicates the cheapest price to be $290. The most popular route (Lambert-St Louis - Jacksonville), is priced around $183.

What are the most popular airlines that fly from St. Louis to Jacksonville?

Before booking your flight from St. Louis to Jacksonville check out the most popular airlines for this route: Southwest, American Airlines or Delta.

Most accurate provider : When it comes to deals on St. Louis-Jacksonville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on St. Louis-Jacksonville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from St. Louis-Jacksonville flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on St. Louis-Jacksonville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Jacksonville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

What airports do I use to fly from St. Louis to Jacksonville?

If you wish to fly to Jacksonville from St. Louis, then you need to book flights from Lambert-St Louis to Jacksonville. There is 1 flight from Lambert-St Louis (STL) to Jacksonville (JAX) per day to choose from. Flights to Jacksonville from Lambert-St Louis are available from 3 different airlines, which means you should have some options if you want to compare airfare deals. 1h 55m is how long a nonstop flight from St. Louis to Jacksonville typically takes.

Can I find deals for flights from St. Louis to Jacksonville that include hotel bookings?

Yes. In addition to deals on St. Louis to Jacksonville flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from St. Louis to Jacksonville?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Jacksonville.

Can I find deals for business class flights from St. Louis to Jacksonville?

Yes. Cheapflights offers flight deals from St. Louis to Jacksonville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$92+ Flights from St. Louis to Jacksonville

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from St. Louis to Jacksonville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Lambert-St Louis to Jacksonville are usually found in October or September, booked 85 days in advance, depart on a Friday or Thursday and return on a Tuesday

Cheap flight deals from St. Louis to Jacksonville

Cheapest flights from St. Louis to Jacksonville
Explore the most affordable flight options available from St. Louis to Jacksonville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

Tue 12/304:53 pmSTL - JAX

1 stop4h 59mAmerican Airlines

Tue 1/66:00 amJAX - STL

1 stop4h 40mAmerican Airlines

Deal found 12/2

$280

Tue 12/309:00 pmSTL - JAX

Nonstop1h 55mSouthwest

Tue 1/65:50 amJAX - STL

1 stop7h 30mSouthwest

Deal found 12/2

$291

Sat 12/204:27 pmSTL - JAX

2 stops27h 04mMultiple Airlines

Mon 12/295:23 pmJAX - STL

1 stop17h 17mMultiple Airlines

Deal found 12/1

$343

Fri 12/196:00 amSTL - JAX

1 stop5h 07mDelta

Fri 1/26:41 pmJAX - STL

1 stop3h 59mDelta

Deal found 12/3

$357

Mon 12/224:27 pmSTL - JAX

2 stops25h 33mMultiple Airlines

Mon 12/295:23 pmJAX - STL

1 stop17h 17mMultiple Airlines

Deal found 12/1

$361

Fri 12/197:05 amSTL - JAX

1 stop4h 02mDelta

Mon 12/297:59 pmJAX - STL

1 stop4h 43mDelta

Deal found 12/1

$367

Fri 12/198:37 pmSTL - JAX

2 stops46h 54mMultiple Airlines

Mon 12/295:23 pmJAX - STL

1 stop17h 17mMultiple Airlines

Deal found 12/1

$369

Mon 12/810:47 amSTL - JAX

1 stop5h 49mMultiple Airlines

Wed 12/1010:33 amJAX - STL

2 stops37h 00mMultiple Airlines

Deal found 12/1

$372

Tue 12/239:00 pmSTL - JAX

Nonstop1h 55mSouthwest

Thu 1/16:15 pmJAX - STL

Nonstop2h 20mSouthwest

Deal found 12/2

$373

Wed 12/246:10 pmSTL - JAX

Nonstop1h 55mSouthwest

Sun 12/285:05 pmJAX - STL

1 stop7h 45mSouthwest

Deal found 12/1

$377

Best flights from St. Louis to Jacksonville
Discover carefully curated flight deals from St. Louis to Jacksonville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 4, 2025.

Tue 2/102:20 pmSTL - JAX

1 stop4h 35mSouthwest

Tue 2/176:30 pmJAX - STL

1 stop5h 10mSouthwest

Deal found 12/3

$183

Wed 3/45:00 pmSTL - JAX

1 stop6h 01mDelta

Wed 3/113:44 pmJAX - STL

1 stop5h 59mDelta

Deal found 12/3

$183

Tue 2/105:04 pmSTL - JAX

1 stop3h 53mDelta

Tue 2/175:30 amJAX - STL

1 stop6h 32mDelta

Deal found 12/1

$183

Mon 1/129:45 amSTL - JAX

1 stop6h 09mDelta

Wed 1/1412:17 pmJAX - STL

1 stop5h 20mDelta

Deal found 12/3

$210

Sat 1/248:45 amSTL - JAX

Nonstop2h 00mSouthwest

Sun 1/256:00 pmJAX - STL

1 stop4h 45mSouthwest

Deal found 12/3

$281

Tue 1/139:59 amSTL - JAX

1 stop5h 31mDelta

Fri 1/165:30 amJAX - STL

1 stop4h 23mDelta

Deal found 12/3

$236

Mon 1/123:45 pmSTL - JAX

1 stop6h 12mDelta

Sat 1/177:30 amJAX - STL

1 stop4h 32mDelta

Deal found 12/4

$237

Sun 1/189:59 amSTL - JAX

1 stop3h 19mDelta

Thu 1/223:12 pmJAX - STL

1 stop3h 38mDelta

Deal found 12/1

$277

Thu 2/197:10 amSTL - JAX

1 stop6h 43mDelta

Sun 2/225:30 amJAX - STL

1 stop6h 32mDelta

Deal found 12/4

$277

Last-minute flights from St. Louis to Jacksonville
Discover last-minute flight deals from St. Louis to Jacksonville. Data last updated December 4, 2025 and is based on user searches.

Sat 1/106:10 amSTL - JAX

1 stop6h 23mDelta

Wed 1/145:30 amJAX - STL

1 stop4h 23mDelta

Deal found 12/3

$210

Sun 1/113:43 pmSTL - JAX

1 stop24h 14mFrontier

Fri 1/168:17 pmJAX - STL

1 stop11h 34mFrontier

Deal found 12/3

$192

Sun 1/113:43 pmSTL - JAX

1 stop24h 14mFrontier

Mon 1/198:17 pmJAX - STL

2 stops43h 29mFrontier

Deal found 12/3

$216

Sun 1/113:43 pmSTL - JAX

1 stop24h 14mMultiple Airlines

Tue 1/2011:37 amJAX - STL

2 stops36h 56mMultiple Airlines

Deal found 12/3

$227

Sun 1/113:43 pmSTL - JAX

1 stop24h 14mMultiple Airlines

Thu 1/1510:05 amJAX - STL

2 stops21h 46mMultiple Airlines

Deal found 12/3

$230

Tue 1/131:18 pmSTL - JAX

1 stop6h 25mDelta

Wed 1/143:28 pmJAX - STL

1 stop4h 44mDelta

Deal found 12/3

$183

Tue 1/1311:35 amSTL - JAX

2 stops8h 00mSouthwest

Sat 1/177:40 amJAX - STL

1 stop6h 10mSouthwest

Deal found 12/3

$215

Tue 1/135:11 pmSTL - JAX

2 stops37h 48mFrontier

Sun 1/184:13 pmJAX - STL

1 stop15h 38mFrontier

Deal found 12/3

$235

Tue 1/139:59 amSTL - JAX

1 stop5h 31mDelta

Fri 1/165:30 amJAX - STL

1 stop4h 23mDelta

Deal found 12/3

$236

Sat 1/3111:05 amSTL - JAX

1 stop8h 53mAmerican Airlines

Thu 2/52:42 pmJAX - STL

1 stop4h 52mAmerican Airlines

Deal found 12/3

$231

One-way flights from St. Louis to Jacksonville
Search for one-way flight options from St. Louis to Jacksonville. Find affordable one-way fares based on user searches. Data last updated December 4, 2025.

Tue 3/31:10 pmSTL - JAX

1 stop7h 53mDelta

Deal found 12/3

$92

Tue 2/35:42 pmSTL - JAX

2 stops23h 51mFrontier

Deal found 12/2

$95

Sun 3/810:42 amSTL - JAX

1 stop19h 30mFrontier

Deal found 12/3

$96

Tue 2/1011:25 amSTL - JAX

2 stops8h 50mSouthwest

Deal found 12/3

$97

Sun 3/15:11 pmSTL - JAX

2 stops24h 19mFrontier

Deal found 12/2

$101

Thu 3/510:42 amSTL - JAX

1 stop19h 30mFrontier

Deal found 12/2

$103

Fri 1/308:22 pmSTL - JAX

1 stop19h 01mFrontier

Deal found 12/2

$105

Fri 12/1210:42 amSTL - JAX

1 stop5h 58mFrontier

Deal found 12/3

$106

Mon 3/23:47 pmSTL - JAX

1 stop5h 05mDelta

Deal found 12/3

$119

Sun 2/15:42 pmSTL - JAX

3 stops23h 41mMultiple Airlines

Deal found 12/2

$122

Thu 2/57:20 pmSTL - JAX

Nonstop1h 55mSouthwest

Deal found 12/2

$123

Thu 1/295:42 pmSTL - JAX

2 stops23h 41mFrontier

Deal found 12/2

$124

Find flight deals from St. Louis to Jacksonville

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$183 (Delta)
One-way from	$92 (Delta)
Popular in	November
Cheapest in	October
Average price	$357
Good round-trip deal	$300 or less

Provider with most accurate pricing for Lambert-St Louis-Jacksonville flight deals.

Search Deals

Provider most trusted by Cheapflights users for Lambert-St Louis-Jacksonville flights.

Search Deals

From Lambert-St Louis to Jacksonville

Search Deals

One-way flight from Lambert-St Louis to Jacksonville

Search Deals

Highest demand for flights based on searches. 8% potential increase in price ($29 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Price to beat on a round-trip flight from Lambert-St Louis to Jacksonville.

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from St. Louis to Jacksonville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisJacksonville

STL - JAX

STLJAX

Lambert-St Louis

Tue 2/10

2:20 pm-7:55 pm

1 stop4h 35m

Jacksonville

Tue 2/17

6:30 pm-10:40 pm

1 stop5h 10m

$183

St. LouisJacksonville

STL - JAX

STLJAX

Lambert-St Louis

Wed 3/4

5:00 pm-12:01 am

1 stop6h 01m

Jacksonville

Wed 3/11

3:44 pm-8:43 pm

1 stop5h 59m

$183

St. LouisJacksonville

STL - JAX

STLJAX

Lambert-St Louis

Tue 2/10

5:04 pm-9:57 pm

1 stop3h 53m

Jacksonville

Tue 2/17

5:30 am-11:02 am

1 stop6h 32m

$183

St. LouisJacksonville

STL - JAX

STLJAX

Lambert-St Louis

Mon 1/12

9:45 am-4:54 pm

1 stop6h 09m

Jacksonville

Wed 1/14

12:17 pm-4:37 pm

1 stop5h 20m

$210

St. LouisJacksonville

STL - JAX

STLJAX

Lambert-St Louis

Tue 1/13

9:59 am-4:30 pm

1 stop5h 31m

Jacksonville

Fri 1/16

5:30 am-8:53 am

1 stop4h 23m

$236

St. LouisJacksonville

STL - JAX

STLJAX

Lambert-St Louis

Mon 1/12

3:45 pm-10:57 pm

1 stop6h 12m

Jacksonville

Sat 1/17

7:30 am-11:02 am

1 stop4h 32m

$237

St. LouisJacksonville

STL - JAX

STLJAX

Lambert-St Louis

Sun 1/18

9:59 am-2:18 pm

1 stop3h 19m

Jacksonville

Thu 1/22

3:12 pm-5:50 pm

1 stop3h 38m

$277

St. LouisJacksonville

STL - JAX

STLJAX

Lambert-St Louis

Thu 2/19

7:10 am-2:53 pm

1 stop6h 43m

Jacksonville

Sun 2/22

5:30 am-11:02 am

1 stop6h 32m

$277

St. LouisJacksonville

STL - JAX

STLJAX

Lambert-St Louis

Sat 1/24

8:45 am-11:45 am

Nonstop2h 00m

Jacksonville

Sun 1/25

6:00 pm-9:45 pm

1 stop4h 45m

$281

St. LouisJacksonville

STL - JAX

STLJAX

Lambert-St Louis

Tue 2/10

5:04 pm-9:57 pm

1 stop3h 53m

$92

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/3

Showing 1-10 of 18 results

Compare providers for flights from St. Louis to Jacksonville

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Jacksonville in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars
Priceline	Price Accuracy1 star	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on St. Louis-Jacksonville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on St. Louis-Jacksonville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from St. Louis-Jacksonville flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on St. Louis-Jacksonville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Jacksonville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from St. Louis to Jacksonville

Have a flexible travel schedule? Discover the best time to fly to Jacksonville from St. Louis with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Jacksonville

How far ahead should I book a flight from St. Louis to Jacksonville?

The price you pay for your flight from St. Louis to Jacksonville may vary depending on when you book. For the best chance of a lower fare, look to book 85 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from St. Louis to Jacksonville?

Currently, October is the cheapest month in which you can book a flight from St. Louis to Jacksonville (average of $163). Flying from St. Louis to Jacksonville in December is currently the most expensive (average of $252). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to JAX?

A simple way to save on the total cost of your ticket is to fly from St. Louis to Jacksonville in the afternoon. If you’re flexible enough to do this you can expect to save up to 32% on your trip compared to booking a flight at noon.

What is the cheapest day to fly from St. Louis to Jacksonville?

Travelers seeking maximum savings on their St. Louis to Jacksonville flight should consider departing on Thursday afternoons when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

The best insider tips for St. Louis to Jacksonville flights

Cheapflights partnered with top experts to bring you the best recommendations for your St. Louis to Jacksonville trip

Airports

STL

Expect security screening at STL to take 5-10 minutes during off-peak times. Check real-time wait times online before heading to the airport.

JAX

At JAX, rental car counters are inside baggage claim. Get your rental while waiting for bags for efficiency.

Our travel experts

Matt Meltzer

Expert on JAX

Taryn White

Expert on STL

Reviews of airlines servicing Jacksonville

Read through reviews of airlines operating flights from St. Louis to Jacksonville, such as Southwest, Delta, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Southwest

8.0

Very good

4,250 reviews

Southwest

8.0

Very good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Delta

7.9

Good

8,011 reviews

Southwest

8.0

Very good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

American Airlines

7.2

Good

11,047 reviews

Southwest

8.0

Very good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

What airports do I use to fly from St. Louis to Jacksonville?
If you wish to fly to Jacksonville from St. Louis, then you need to book flights from Lambert-St Louis to Jacksonville. There is 1 flight from Lambert-St Louis (STL) to Jacksonville (JAX) per day to choose from. Flights to Jacksonville from Lambert-St Louis are available from 3 different airlines, which means you should have some options if you want to compare airfare deals. 1h 55m is how long a nonstop flight from St. Louis to Jacksonville typically takes.
How popular is this St. Louis to Jacksonville flight route?
Flights from Lambert-St Louis to Jacksonville have been viewed 6 times in the past calendar month.
How long is the flight from St. Louis to Jacksonville?
Southwest and Delta can get you from St. Louis to Jacksonville in just under 4h 35m. Your travel time can differ by up to 1h 26m. Airlines will cover a distance of 753 mi. This flight may include one or multiple stops.
What are the cheapest airlines flying from St. Louis to Jacksonville round-trip?
According to our current data, American Airlines ($186), Delta ($202), and Southwest ($214) offers the cheapest pricing from St. Louis to Jacksonville. You may be able to fly from St. Louis to Jacksonville for 40% less than the average price by searching for these airlines.
What are the cheapest airlines to fly from St. Louis to Jacksonville one-way?
For one-way options, check prices for Delta. According to our data, you can fly for as low as $66. Users have also found prices from $94 and $109 on Southwest and American Airlines, respectively.
What are the cheapest flights from St. Louis to Jacksonville?
Looking for the cheapest flight from St. Louis to Jacksonville? While on average our users pay $394, our data indicates the cheapest price to be $290. The most popular route (Lambert-St Louis - Jacksonville), is priced around $183.
Can I find deals for flights from St. Louis to Jacksonville that include hotel bookings?
Yes. In addition to deals on St. Louis to Jacksonville flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from St. Louis to Jacksonville?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Jacksonville.
Can I find deals for business class flights from St. Louis to Jacksonville?
Yes. Cheapflights offers flight deals from St. Louis to Jacksonville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from St. Louis to Jacksonville?
Currently, October is the cheapest month in which you can book a flight from St. Louis to Jacksonville (average of $163). Flying from St. Louis to Jacksonville in December is currently the most expensive (average of $252). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Jacksonville Beach

Orange Park

Fernandina Beach

Kingsland

Waycross

Browse thousands of different options on Cheapflights for your next trip

Top 3 airlines flying from St. Louis to Jacksonville

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$186	Average$284	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$205	Average$301	FlexibilityNo cancel fee	On-timeN/A
Southwest	Cheapest$214	Average$317	FlexibilityNo cancel fee	On-time63%

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$92+ Cheap flights from St. Louis to Jacksonville (STL - JAX)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/10. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from St. Louis to Jacksonville with Cheapflights

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2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Lambert-St Louis to Jacksonville are usually found in October or September, booked 85 days in advance, depart on a Friday or Thursday and return on a Tuesday

Cheap flight deals from St. Louis to Jacksonville

Cheapest flights from St. Louis to JacksonvilleExplore the most affordable flight options available from St. Louis to Jacksonville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

Explore the most affordable flight options available from St. Louis to Jacksonville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

Find flight deals from St. Louis to Jacksonville

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Cheapflights Fare Finder

Use the filters below to find and compare flights from St. Louis to Jacksonville that are best for you.

Compare providers for flights from St. Louis to Jacksonville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Jacksonville in December.

Best time to book a flight from St. Louis to Jacksonville

Have a flexible travel schedule? Discover the best time to fly to Jacksonville from St. Louis with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Jacksonville

How far ahead should I book a flight from St. Louis to Jacksonville?

What is the cheapest month to book a flight from St. Louis to Jacksonville?

What is the cheapest time of day to fly from STL to JAX?

What is the cheapest day to fly from St. Louis to Jacksonville?

The best insider tips for St. Louis to Jacksonville flights

AI-powered summary based on content written by travel experts. AI can make mistakes.

Cheapflights partnered with top experts to bring you the best recommendations for your St. Louis to Jacksonville trip

Airports

STL

JAX

Our travel experts

Reviews of airlines servicing Jacksonville

Read through reviews of airlines operating flights from St. Louis to Jacksonville, such as Southwest, Delta, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Jacksonville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airports do I use to fly from St. Louis to Jacksonville?

How popular is this St. Louis to Jacksonville flight route?

How long is the flight from St. Louis to Jacksonville?

What are the cheapest airlines flying from St. Louis to Jacksonville round-trip?

What are the cheapest airlines to fly from St. Louis to Jacksonville one-way?

What are the cheapest flights from St. Louis to Jacksonville?

Can I find deals for flights from St. Louis to Jacksonville that include hotel bookings?

How can I find direct flights from St. Louis to Jacksonville?

Can I find deals for business class flights from St. Louis to Jacksonville?

What is the cheapest month to book a flight from St. Louis to Jacksonville?

Traveling to a place near Jacksonville?

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Alternative routes for St. Louis to Jacksonville

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Top 3 airlines flying from St. Louis to Jacksonville

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Cheapest flights from St. Louis to Jacksonville
Explore the most affordable flight options available from St. Louis to Jacksonville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.