$343+ Cheap flights from South Carolina to Italy
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/27. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — NAP
Oct 23 — Oct 301
Round-trip
1 adult, Economy
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Find cheap flights from South Carolina to Italy with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from South Carolina to ItalyExplore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 23, 2026.
Explore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 23, 2026.
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2611:12 am -
1 stop19h 18m
Tue 11/1010:25 am -
2 stops14h 21m
Deal found 9/23![American Airlines logo]()
$552
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/87:14 pm -
1 stop33h 31m
Tue 11/1712:55 pm -
1 stop15h 17m
Deal found 9/21![Delta logo]()
$553
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1411:45 am -
1 stop15h 40m
Tue 11/1712:55 pm -
1 stop15h 17m
Deal found 9/22![Delta logo]()
$561
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/110:23 am -
1 stop15h 07m
Thu 12/109:45 am -
1 stop20h 14m
Deal found 9/21![United Airlines logo]()
$561
This Booking.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2611:12 am -
1 stop18h 43m
Tue 11/1011:00 am -
1 stop18h 18m
Deal found 9/21![British Airways logo]()
$564
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/264:34 pm -
2 stops15h 21m
Tue 11/1011:00 am -
2 stops17h 51m
Deal found 9/21![American Airlines logo]()
$566
This Gotogate deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/110:23 am -
2 stops18h 32m
Tue 12/811:15 am -
2 stops33h 05m
Deal found 9/23![Air Canada logo]()
$570
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/213:05 pm -
1 stop13h 50m
Wed 11/1110:30 am -
1 stop19h 29m
Deal found 9/21![United Airlines logo]()
$577
This Air France deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/264:20 pm -
2 stops14h 35m
Tue 11/1012:00 pm -
1 stop14h 24m
Deal found 9/23![Air France logo]()
$580
This Iberia deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/112:17 pm -
2 stops18h 18m
Thu 12/1010:10 am -
2 stops19h 49m
Deal found 9/18![Multiple Airlines logo]()
$581
This Expedia deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/13:58 pm -
2 stops15h 57m
Tue 12/81:00 pm -
1 stop34h 38m
Deal found 9/23![Multiple Airlines logo]()
$591
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/87:14 pm -
1 stop33h 31m
Thu 11/1912:55 pm -
1 stop15h 17m
Deal found 9/20![Delta logo]()
$596
Best flights from South Carolina to ItalyDiscover carefully curated flight deals from South Carolina to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 23, 2026.
Discover carefully curated flight deals from South Carolina to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 23, 2026.
This Air France deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/264:20 pm -
1 stop12h 35m
Tue 11/1012:00 pm -
1 stop14h 24m
Deal found 9/23![Air France logo]()
$561
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/110:23 am -
1 stop15h 07m
Thu 12/109:45 am -
1 stop20h 14m
Deal found 9/18![United Airlines logo]()
$562
This Justfly.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/310:57 am -
2 stops26h 28m
Tue 3/911:00 am -
1 stop17h 21m
Deal found 9/18![British Airways logo]()
$581
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1411:05 am -
2 stops21h 40m
Tue 11/1712:00 pm -
2 stops29h 07m
Deal found 9/23![Delta logo]()
$585
This KLM deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/252:16 pm -
1 stop16h 04m
Tue 11/1010:25 am -
1 stop18h 29m
Deal found 9/20![KLM logo]()
$617
This KLM deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/148:05 am -
1 stop17h 30m
Fri 11/611:45 am -
2 stops17h 06m
Deal found 9/20![Multiple Airlines logo]()
$621
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/58:32 pm -
2 stops16h 53m
Thu 11/126:20 am -
2 stops19h 22m
Deal found 9/21![American Airlines logo]()
$764
This Expedia deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/62:30 pm -
2 stops16h 20m
Sat 2/131:35 pm -
2 stops15h 44m
Deal found 9/21![Lufthansa logo]()
$769
This Booking.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/106:00 am -
2 stops22h 05m
Fri 1/1512:55 pm -
3 stops40h 24m
Deal found 9/23![Air Canada logo]()
$823
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/262:52 pm -
2 stops14h 48m
Tue 11/109:45 am -
2 stops18h 15m
Deal found 9/23![United Airlines logo]()
$597
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2011:45 am -
1 stop15h 40m
Mon 11/1612:00 pm -
2 stops29h 07m
Deal found 9/19![Delta logo]()
$616
This KLM deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/148:05 am -
1 stop17h 30m
Fri 11/610:25 am -
1 stop15h 56m
Deal found 9/20![KLM logo]()
$617
This KLM deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2511:45 am -
1 stop18h 35m
Thu 11/511:45 am -
2 stops17h 06m
Deal found 9/19![Multiple Airlines logo]()
$621
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:00 am -
1 stop20h 15m
Wed 12/91:30 pm -
1 stop15h 17m
Deal found 9/20![Delta logo]()
$617
This British Airways deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/151:13 pm -
1 stop14h 52m
Thu 10/222:20 pm -
1 stop33h 34m
Deal found 9/21![British Airways logo]()
$697
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/143:00 pm -
1 stop11h 15m
Thu 10/2210:20 am -
1 stop19h 55m
Deal found 9/23![United Airlines logo]()
$636
This British Airways deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/412:17 pm -
2 stops17h 03m
Wed 11/111:20 pm -
1 stop36h 14m
Deal found 9/20![Multiple Airlines logo]()
$639
This KLM deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/310:52 am -
2 stops14h 53m
Tue 11/1010:00 am -
2 stops18h 54m
Deal found 9/19![KLM logo]()
$660
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/98:05 am -
2 stops17h 40m
Wed 11/1810:00 am -
1 stop14h 10m
Deal found 9/19![Delta logo]()
$621
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/412:18 pm -
1 stop18h 57m
Wed 11/119:45 am -
1 stop13h 54m
Deal found 9/20![United Airlines logo]()
$641
This Finnair deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/137:00 am -
2 stops28h 55m
Sun 12/206:40 pm -
2 stops33h 57m
Deal found 9/23![Multiple Airlines logo]()
$642
This KLM deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:05 am -
1 stop17h 30m
Thu 11/510:00 am -
1 stop17h 27m
Deal found 9/18![KLM logo]()
$667
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:53 pm -
1 stop11h 22m
Fri 10/2310:20 am -
1 stop34h 50m
Deal found 9/22![United Airlines logo]()
$642
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/34:30 pm -
1 stop12h 50m
Tue 11/1010:00 am -
2 stops18h 54m
Deal found 9/19![Delta logo]()
$660
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/47:20 am -
1 stop23h 40m
Mon 10/123:00 pm -
1 stop14h 59m
Deal found 9/19![American Airlines logo]()
$891
This KLM deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/171:20 pm -
1 stop16h 00m
Sun 2/281:30 pm -
1 stop16h 24m
Deal found 9/20![KLM logo]()
$672
This Air Canada deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/311:12 am -
3 stops20h 23m
Tue 11/107:00 am -
3 stops22h 59m
Deal found 9/19![Air Canada logo]()
$966
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:00 am -
2 stops18h 45m
Tue 12/112:55 pm -
2 stops16h 56m
Deal found 9/18![Delta logo]()
$661
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/146:10 am -
2 stops20h 45m
Wed 3/249:45 am -
2 stops18h 34m
Deal found 9/23![United Airlines logo]()
$665
This KLM deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/1510:14 am -
1 stop19h 06m
Mon 3/11:30 pm -
1 stop13h 51m
Deal found 9/22![KLM logo]()
$672
Last-minute flights from South Carolina to ItalyDiscover last-minute flight deals from South Carolina to Italy. Data last updated September 23, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Italy. Data last updated September 23, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1411:45 am -
1 stop15h 40m
Tue 11/1712:55 pm -
1 stop15h 17m
Deal found 9/22![Delta logo]()
$561
This Air France deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/148:05 am -
1 stop19h 20m
Tue 11/1712:55 pm -
1 stop15h 17m
Deal found 9/20![Multiple Airlines logo]()
$603
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:40 am -
1 stop19h 55m
Fri 11/610:00 am -
1 stop17h 27m
Deal found 9/18![Delta logo]()
$617
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:00 am -
2 stops17h 45m
Mon 11/1612:00 pm -
2 stops29h 07m
Deal found 9/22![Delta logo]()
$616
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/213:05 pm -
1 stop13h 50m
Wed 11/1110:30 am -
1 stop19h 29m
Deal found 9/21![United Airlines logo]()
$577
This Air Canada deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2111:05 am -
2 stops16h 10m
Wed 11/119:55 am -
3 stops20h 04m
Deal found 9/21![Multiple Airlines logo]()
$612
This KLM deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/252:16 pm -
1 stop16h 04m
Tue 11/1010:25 am -
1 stop18h 29m
Deal found 9/20![KLM logo]()
$617
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2611:12 am -
1 stop19h 18m
Tue 11/1010:25 am -
2 stops14h 21m
Deal found 9/23![American Airlines logo]()
$552
This Air France deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/264:20 pm -
1 stop12h 35m
Tue 11/1012:00 pm -
1 stop14h 24m
Deal found 9/23![Air France logo]()
$561
This Booking.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2611:12 am -
1 stop18h 43m
Tue 11/1011:00 am -
1 stop18h 18m
Deal found 9/21![British Airways logo]()
$564
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/264:34 pm -
2 stops15h 21m
Tue 11/1011:00 am -
2 stops17h 51m
Deal found 9/21![American Airlines logo]()
$566
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/262:52 pm -
2 stops14h 48m
Tue 11/109:45 am -
2 stops18h 15m
Deal found 9/23![United Airlines logo]()
$597
One-way flights from South Carolina to ItalySearch for one-way flight options from South Carolina to Italy. Find affordable one-way fares based on user searches. Data last updated September 23, 2026.
Search for one-way flight options from South Carolina to Italy. Find affordable one-way fares based on user searches. Data last updated September 23, 2026.
This FlightHub deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/274:48 pm -
2 stops37h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![British Airways logo]()
$343
This oojo deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/152:30 pm -
1 stop12h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Lufthansa logo]()
$345
This oojo deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/2012:15 pm -
1 stop13h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Lufthansa logo]()
$345
This Mytrip deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2210:57 am -
2 stops20h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![British Airways logo]()
$349
This KLM deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/222:25 pm -
1 stop15h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![KLM logo]()
$355
This Justfly.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/2010:54 am -
2 stops22h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![British Airways logo]()
$356
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:32 pm -
3 stops42h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Multiple Airlines logo]()
$372
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/184:02 pm -
3 stops24h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Multiple Airlines logo]()
$385
This Air Canada deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/2710:12 am -
3 stops21h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Air Canada logo]()
$403
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/189:18 pm -
2 stops45h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$408
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/48:48 pm -
2 stops46h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Multiple Airlines logo]()
$428
This Cheapflightsfares deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:00 am -
2 stops22h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Aer Lingus logo]()
$434
Find flight deals from South Carolina to Italy
Keep the following information in mind while searching for South Carolina to Italy flight deals. Data was last updated September 23, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $552 (American Airlines) |
One-way from | $343 (FlightHub) |
Popular in | June |
Cheapest in | February |
Average price | $1,300 |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 23, 2026.
Use the filters below to find and compare flights from South Carolina to Italy that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonVenice
CHS Charleston - VCE Venice Marco Polo
CHSVCE
Charleston
Wed 1/27
4:48 pm-12:35 pm
2 stops37h 47m
Venice Marco Polo
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$343
GreenvilleRome
GSP Greenville - FCO Rome Fiumicino
GSPFCO
Greenville
Wed 1/20
12:15 pm-7:55 am
1 stop13h 40m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$345
CharlestonRome
CHS Charleston - FCO Rome Fiumicino
CHSFCO
Charleston
Mon 3/22
2:25 pm-11:20 am
1 stop15h 55m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$355
GreenvilleRome
GSP Greenville - FCO Rome Fiumicino
GSPFCO
Greenville
Wed 1/20
10:54 am-2:55 pm
2 stops22h 01m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$356
CharlestonRome
CHS Charleston - FCO Rome Fiumicino
CHSFCO
Charleston
Mon 3/15
10:30 am-9:35 am
2 stops18h 05m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$360
CharlestonVenice
CHS Charleston - VCE Venice Marco Polo
CHSVCE
Charleston
Wed 1/27
10:12 am-2:00 pm
3 stops21h 48m
Venice Marco Polo
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$403
Myrtle BeachRome
MYR Myrtle Beach Intl - FCO Rome Fiumicino
MYRFCO
Myrtle Beach Intl
Wed 11/4
8:48 pm-12:50 am
2 stops46h 02m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$428
CharlestonRome
CHS Charleston - FCO Rome Fiumicino
CHSFCO
Charleston
Mon 3/22
7:40 pm-8:30 am
1 stop31h 50m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$443
Myrtle BeachRome
MYR Myrtle Beach Intl - FCO Rome Fiumicino
MYRFCO
Myrtle Beach Intl
Wed 11/4
11:27 am-7:55 am
1 stop14h 28m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$447
GreenvilleRome
GSP Greenville - FCO Rome Fiumicino
GSPFCO
Greenville
Tue 10/27
6:20 am-7:45 am
1 stop20h 25m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$447
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Italy
Have a flexible travel schedule? Discover the best time to fly to Italy from South Carolina with our price prediction graph.
CHS-MXP
GSP-MXP
CHS-FCO
MYR-FCO
GSP-FCO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Italy
USSC-IT0
CHS-MXP
GSP-MXP
CHS-FCO
MYR-FCO
What is the cheapest month to book a flight from South Carolina to Italy?
Currently, February is the cheapest month in which you can book a flight from South Carolina to Italy (average of $527). Flying from South Carolina to Italy in June is currently the most expensive (average of $1,524). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from South Carolina to Italy?
The price you pay for your flight from South Carolina to Italy may vary depending on when you book. For the best chance of a lower fare, look to book 47 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for South Carolina to Italy
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Italy by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Italy by cabin class
Find flights from South Carolina to Italy, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Carolina and Italy flights
Browse other South Carolina and Italy flight options. Last updated on September 23, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Italy
Find the right flight back to South Carolina after your stay in Italy
South Carolina to Italy flights
Consider these flights traveling from South Carolina to Italy.
Fly to Italy regions
Consider these flights traveling to Italy regions.
Top 5 airlines flying from South Carolina to Italy
Discover the top 5 airlines that operate flights from South Carolina to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$307 | Average$1,168 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$497 | Average$1,362 | FlexibilityNo cancel fee | On-time76% | |
| Cheapest$503 | Average$1,269 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$609 | Average$1,175 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$759 | Average$1,312 | FlexibilityNo cancel fee | On-time71% |