$319+ Cheap flights from South Carolina to Italy
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/28. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — NAP
May 2 — May 91
Round-trip
1 adult, Economy
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Cheapest flights from South Carolina to ItalyExplore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 2, 2026.
Explore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 2, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:40 pm
CLT
- VCE
1 stop12h 05m
Lufthansa
Wed 8/196:30 am
VCE
- CLT
1 stop16h 15m
Lufthansa
Deal found 3/31![Lufthansa logo]()
$674
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:40 pm
CLT
- MXP
1 stop16h 00m
Lufthansa
Wed 4/226:20 am
MXP
- CLT
1 stop16h 25m
Lufthansa
Deal found 3/30![Lufthansa logo]()
$680
This Cheapflightsfares deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:40 pm
CLT
- LIN
1 stop12h 20m
Lufthansa
Wed 4/228:45 am
LIN
- CLT
1 stop14h 00m
Lufthansa
Deal found 3/31![Lufthansa logo]()
$689
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:40 pm
CLT
- MXP
1 stop11h 35m
Multiple Airlines
Wed 4/225:50 am
MXP
- CLT
2 stops17h 34m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$689
This Cheapflightsfares deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:05 am
CLT
- VCE
2 stops28h 45m
SWISS
Wed 8/1910:20 am
VCE
- CLT
2 stops17h 10m
SWISS
Deal found 3/31![SWISS logo]()
$692
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/266:40 pm
CLT
- MXP
1 stop16h 00m
Lufthansa
Tue 5/56:20 am
MXP
- CLT
1 stop16h 25m
Lufthansa
Deal found 3/30![Lufthansa logo]()
$706
This United Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/165:28 pm
CLT
- MXP
1 stop13h 37m
United Airlines
Fri 11/201:05 pm
MXP
- CLT
2 stops38h 18m
United Airlines
Deal found 3/30![United Airlines logo]()
$707
This Cheapflightsfares deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:40 pm
CLT
- MXP
1 stop11h 35m
Lufthansa
Wed 10/218:45 am
MXP
- CLT
1 stop14h 00m
Lufthansa
Deal found 3/31![Lufthansa logo]()
$710
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/266:40 pm
CLT
- LIN
1 stop12h 20m
Lufthansa
Tue 5/58:45 am
LIN
- CLT
1 stop14h 00m
Lufthansa
Deal found 3/30![Lufthansa logo]()
$713
This FlightHub deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/13:40 pm
CLT
- MXP
2 stops36h 40m
Air Canada
Wed 8/2612:20 pm
MXP
- CLT
2 stops41h 38m
Air Canada
Deal found 3/31![Air Canada logo]()
$713
This FlightHub deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/266:00 am
CLT
- FLR
2 stops31h 05m
Scandinavian Airlines
Tue 5/57:55 pm
FLR
- CLT
2 stops32h 16m
Scandinavian Airlines
Deal found 3/31![Scandinavian Airlines logo]()
$714
This Cheapflightsfares deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:40 pm
CLT
- LIN
1 stop12h 20m
Lufthansa
Wed 10/219:50 am
LIN
- CLT
1 stop12h 55m
Lufthansa
Deal found 3/31![Lufthansa logo]()
$714
Best flights from South Carolina to ItalyDiscover carefully curated flight deals from South Carolina to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 2, 2026.
Discover carefully curated flight deals from South Carolina to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 2, 2026.
This United Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:40 pm
CLT
- MXP
1 stop16h 00m
United Airlines
Wed 4/2212:20 pm
MXP
- CLT
2 stops38h 37m
United Airlines
Deal found 3/29![United Airlines logo]()
$710
This British Airways deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/161:04 pm
CLT
- FLR
2 stops16h 46m
Multiple Airlines
Thu 8/277:05 am
FLR
- CLT
2 stops18h 03m
Multiple Airlines
Deal found 4/1![Multiple Airlines logo]()
$725
This Turkish Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/911:13 am
CHS
- MXP
2 stops54h 32m
Turkish Airlines
Mon 5/257:45 pm
MXP
- CHS
2 stops52h 22m
Turkish Airlines
Deal found 3/31![Turkish Airlines logo]()
$779
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/277:59 pm
CLT
- LIN
2 stops17h 46m
Delta
Fri 5/156:40 am
LIN
- CLT
2 stops21h 26m
Delta
Deal found 3/30![Delta logo]()
$792
This Cheapflightsfares deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:53 pm
CHS
- LIN
2 stops16h 52m
Lufthansa
Mon 5/189:50 am
LIN
- CHS
2 stops20h 09m
Lufthansa
Deal found 4/1![Lufthansa logo]()
$850
This SWISS deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SWISS is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:40 pm
CLT
- VCE
2 stops32h 55m
SWISS
Tue 5/56:50 am
VCE
- CLT
2 stops39h 55m
SWISS
Deal found 3/29![SWISS logo]()
$878
This KLM deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:00 am
CHS
- MXP
1 stop18h 45m
KLM
Wed 5/1311:40 am
MXP
- CHS
1 stop16h 12m
KLM
Deal found 3/30![KLM logo]()
$889
This British Airways deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1710:49 am
CHS
- FCO
1 stop18h 31m
British Airways
Fri 8/211:30 pm
FCO
- CHS
1 stop14h 34m
British Airways
Deal found 3/29![British Airways logo]()
$990
This Finnair deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:35 pm
CLT
- FCO
Nonstop9h 15m
Finnair
Tue 5/52:15 pm
FCO
- CLT
Nonstop10h 40m
Finnair
Deal found 4/1![Finnair logo]()
$1,079
This Scandinavian Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Scandinavian Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/79:45 am
CLT
- FCO
3 stops26h 50m
Scandinavian Airlines
Thu 5/2110:10 am
FCO
- CLT
2 stops17h 49m
Scandinavian Airlines
Deal found 3/29![Scandinavian Airlines logo]()
$1,163
This British Airways deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/111:04 pm
CLT
- FLR
2 stops16h 31m
Multiple Airlines
Fri 8/217:05 am
FLR
- CLT
2 stops18h 03m
Multiple Airlines
Deal found 3/28![Multiple Airlines logo]()
$726
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:28 pm
CLT
- MXP
1 stop13h 52m
United Airlines
Wed 5/1312:20 pm
MXP
- CLT
2 stops31h 22m
United Airlines
Deal found 4/1![United Airlines logo]()
$760
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/287:59 pm
CLT
- LIN
2 stops17h 46m
Delta
Tue 5/1211:00 am
LIN
- CLT
2 stops17h 06m
Delta
Deal found 3/30![Delta logo]()
$792
This United Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/510:34 am
CLT
- MXP
1 stop20h 46m
United Airlines
Wed 5/1312:20 pm
MXP
- CLT
2 stops31h 22m
United Airlines
Deal found 4/2![United Airlines logo]()
$761
This Turkish Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:40 pm
CHS
- MXP
2 stops32h 00m
Multiple Airlines
Mon 9/2810:40 am
MXP
- CHS
2 stops31h 27m
Multiple Airlines
Deal found 3/28![Multiple Airlines logo]()
$779
This Cheapflightsfares deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:53 pm
CHS
- LIN
2 stops16h 37m
Lufthansa
Wed 5/1310:35 am
LIN
- CHS
2 stops19h 24m
Lufthansa
Deal found 3/30![Lufthansa logo]()
$862
This KLM deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:00 am
CHS
- MXP
1 stop18h 45m
KLM
Mon 5/1811:40 am
MXP
- CHS
1 stop14h 44m
KLM
Deal found 4/2![KLM logo]()
$889
This SWISS deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SWISS is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:40 pm
CLT
- FLR
2 stops42h 15m
SWISS
Tue 5/510:45 am
FLR
- CLT
2 stops36h 00m
SWISS
Deal found 3/30![SWISS logo]()
$893
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/612:25 pm
CHS
- MXP
2 stops17h 40m
Delta
Tue 5/129:00 am
MXP
- CHS
2 stops19h 56m
Delta
Deal found 3/30![Delta logo]()
$833
This United Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:40 pm
CLT
- FLR
1 stop12h 00m
United Airlines
Thu 8/208:15 am
FLR
- CLT
1 stop14h 30m
United Airlines
Deal found 3/31![United Airlines logo]()
$770
This Turkish Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/611:24 am
CHS
- MXP
2 stops39h 16m
Multiple Airlines
Tue 5/122:55 pm
MXP
- CHS
2 stops32h 02m
Multiple Airlines
Deal found 4/1![Multiple Airlines logo]()
$779
This KAYAK deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/267:40 pm
CHS
- LIN
2 stops34h 20m
Lufthansa
Tue 10/66:25 pm
LIN
- CHS
2 stops35h 26m
Lufthansa
Deal found 3/28![Lufthansa logo]()
$873
This SWISS deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SWISS is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:40 pm
CLT
- MXP
2 stops23h 00m
SWISS
Sun 8/167:25 pm
MXP
- CLT
2 stops27h 20m
SWISS
Deal found 3/29![SWISS logo]()
$904
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/63:10 pm
CHS
- LIN
2 stops14h 10m
Delta
Wed 5/136:40 am
LIN
- CHS
2 stops18h 46m
Delta
Deal found 3/30![Delta logo]()
$840
This Turkish Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:40 pm
CHS
- FCO
2 stops46h 55m
Multiple Airlines
Mon 9/2810:45 am
FCO
- CHS
2 stops31h 22m
Multiple Airlines
Deal found 3/28![Multiple Airlines logo]()
$794
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/62:50 pm
CLT
- LIN
2 stops15h 30m
United Airlines
Wed 5/1310:35 am
LIN
- CLT
2 stops16h 34m
United Airlines
Deal found 4/1![United Airlines logo]()
$795
This KLM deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:00 am
CHS
- FCO
1 stop19h 55m
KLM
Wed 5/2010:10 am
FCO
- CHS
1 stop16h 36m
KLM
Deal found 3/28![KLM logo]()
$980
This Cheapflightsfares deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:40 pm
CLT
- FLR
1 stop12h 10m
Lufthansa
Tue 5/59:50 am
FLR
- CLT
1 stop12h 55m
Lufthansa
Deal found 3/28![Lufthansa logo]()
$902
This Delta deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/275:00 pm
CHS
- LIN
2 stops14h 55m
Delta
Mon 9/2810:25 pm
LIN
- CHS
2 stops23h 15m
Delta
Deal found 3/28![Delta logo]()
$840
This Cheapflightsfares deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/218:05 am
CLT
- VCE
2 stops28h 45m
SWISS
Sun 10/47:40 pm
VCE
- CLT
2 stops27h 05m
SWISS
Deal found 3/28![SWISS logo]()
$939
Last-minute flights from South Carolina to ItalyDiscover last-minute flight deals from South Carolina to Italy. Data last updated April 2, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Italy. Data last updated April 2, 2026 and is based on user searches.
This Cheapflightsfares deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:40 pm
CLT
- MXP
1 stop16h 00m
Lufthansa
Thu 4/236:20 am
MXP
- CLT
1 stop16h 25m
Lufthansa
Deal found 3/31![Lufthansa logo]()
$710
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:40 pm
CLT
- MXP
1 stop16h 00m
Lufthansa
Wed 4/226:20 am
MXP
- CLT
1 stop16h 25m
Lufthansa
Deal found 3/30![Lufthansa logo]()
$680
This Cheapflightsfares deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:40 pm
CLT
- LIN
1 stop12h 20m
Lufthansa
Wed 4/228:45 am
LIN
- CLT
1 stop14h 00m
Lufthansa
Deal found 3/31![Lufthansa logo]()
$689
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:40 pm
CLT
- MXP
1 stop11h 35m
Multiple Airlines
Wed 4/225:50 am
MXP
- CLT
2 stops17h 34m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$689
This FlightHub deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1711:18 am
CHS
- FCO
2 stops30h 17m
Multiple Airlines
Mon 4/2010:50 am
FCO
- CHS
2 stops29h 38m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$732
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/266:40 pm
CLT
- MXP
1 stop16h 00m
Lufthansa
Tue 5/56:20 am
MXP
- CLT
1 stop16h 25m
Lufthansa
Deal found 3/30![Lufthansa logo]()
$706
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/266:40 pm
CLT
- LIN
1 stop12h 20m
Lufthansa
Tue 5/58:45 am
LIN
- CLT
1 stop14h 00m
Lufthansa
Deal found 3/30![Lufthansa logo]()
$713
This FlightHub deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/266:00 am
CLT
- FLR
2 stops31h 05m
Scandinavian Airlines
Tue 5/57:55 pm
FLR
- CLT
2 stops32h 16m
Scandinavian Airlines
Deal found 3/31![Scandinavian Airlines logo]()
$714
This FlightHub deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:00 pm
CLT
- MXP
2 stops20h 10m
Scandinavian Airlines
Mon 5/1111:25 am
MXP
- CLT
2 stops17h 22m
Scandinavian Airlines
Deal found 3/30![Scandinavian Airlines logo]()
$716
This Mytrip deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/310:16 am
CLT
- MXP
2 stops27h 34m
Multiple Airlines
Sat 5/98:40 pm
MXP
- CLT
2 stops26h 31m
Multiple Airlines
Deal found 3/28![Multiple Airlines logo]()
$717
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:28 pm
CLT
- FCO
1 stop15h 02m
Multiple Airlines
Mon 5/187:05 pm
FCO
- CLT
1 stop32h 56m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$724
This FlightHub deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:55 pm
CHS
- FCO
2 stops23h 40m
Turkish Airlines
Mon 5/258:00 pm
FCO
- CHS
2 stops52h 07m
Turkish Airlines
Deal found 3/29![Turkish Airlines logo]()
$735
One-way flights from South Carolina to ItalySearch for one-way flight options from South Carolina to Italy. Find affordable one-way fares based on user searches. Data last updated April 2, 2026.
Search for one-way flight options from South Carolina to Italy. Find affordable one-way fares based on user searches. Data last updated April 2, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:00 am
CLT
- FCO
2 stops37h 15m
Multiple Airlines
Deal found 3/29![Multiple Airlines logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/303:31 pm
CLT
- FCO
3 stops48h 39m
Multiple Airlines
Deal found 4/1![Multiple Airlines logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/121:46 pm
CLT
- FCO
3 stops43h 14m
Multiple Airlines
Deal found 3/28![Multiple Airlines logo]()
$343
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/169:32 pm
CLT
- FCO
2 stops34h 58m
Multiple Airlines
Deal found 3/28![Multiple Airlines logo]()
$349
This Gotogate deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:40 pm
CLT
- FLR
1 stop12h 00m
Lufthansa
Deal found 3/29![Lufthansa logo]()
$360
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/127:12 am
CLT
- VCE
2 stops30h 38m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$361
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/185:30 pm
CLT
- FCO
2 stops49h 55m
Multiple Airlines
Deal found 3/28![Multiple Airlines logo]()
$364
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1710:16 am
CLT
- FCO
1 stop22h 14m
Multiple Airlines
Deal found 3/28![Multiple Airlines logo]()
$365
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:40 pm
CLT
- FLR
2 stops18h 15m
SWISS
Deal found 3/29![SWISS logo]()
$367
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/121:46 pm
CLT
- NAP
3 stops41h 24m
Multiple Airlines
Deal found 3/28![Multiple Airlines logo]()
$380
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/185:30 pm
CLT
- NAP
2 stops43h 45m
Multiple Airlines
Deal found 3/28![Multiple Airlines logo]()
$382
This Kiwi.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/267:12 am
CLT
- MXP
3 stops45h 58m
Multiple Airlines
Deal found 4/2![Multiple Airlines logo]()
$383
Find flight deals from South Carolina to Italy
Keep the following information in mind while searching for South Carolina to Italy flight deals. Data was last updated April 2, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $674 (Cheapflightsfares) |
One-way from | $319 (Kiwi.com) |
Popular in | June |
Cheapest in | January |
Average price | $891 |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 2, 2026.
Use the filters below to find and compare flights from South Carolina to Italy that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlotteMilan
CLT - MXP
CLTMXP
Charlotte Douglas
Wed 4/15
6:40 pm-4:40 pm
1 stop16h 00m
Milan Malpensa
Wed 4/22
12:20 pm-8:57 pm
2 stops38h 37m
$710
CharlotteFlorence
CLT - FLR
CLTFLR
Charlotte Douglas
Sun 8/16
1:04 pm-11:50 am
2 stops16h 46m
Florence Peretola
Thu 8/27
7:05 am-7:08 pm
2 stops18h 03m
$725
CharlotteFlorence
CLT - FLR
CLTFLR
Charlotte Douglas
Tue 8/11
1:04 pm-11:35 am
2 stops16h 31m
Florence Peretola
Fri 8/21
7:05 am-7:08 pm
2 stops18h 03m
$726
CharlotteMilan
CLT - MXP
CLTMXP
Charlotte Douglas
Wed 5/6
5:28 pm-1:20 pm
1 stop13h 52m
Milan Malpensa
Wed 5/13
12:20 pm-1:42 pm
2 stops31h 22m
$760
CharlotteMilan
CLT - MXP
CLTMXP
Charlotte Douglas
Tue 5/5
10:34 am-1:20 pm
1 stop20h 46m
Milan Malpensa
Wed 5/13
12:20 pm-1:42 pm
2 stops31h 22m
$761
CharlotteFlorence
CLT - FLR
CLTFLR
Charlotte Douglas
Sun 8/16
6:40 pm-12:40 pm
1 stop12h 00m
Florence Peretola
Thu 8/20
8:15 am-4:45 pm
1 stop14h 30m
$770
CharlestonMilan
CHS - MXP
CHSMXP
Charleston
Sat 5/9
11:13 am-11:45 pm
2 stops54h 32m
Milan Malpensa
Mon 5/25
7:45 pm-6:07 pm
2 stops52h 22m
$779
CharlestonMilan
CHS - MXP
CHSMXP
Charleston
Fri 9/18
6:40 pm-8:40 am
2 stops32h 00m
Milan Malpensa
Mon 9/28
10:40 am-12:07 pm
2 stops31h 27m
$779
CharlestonMilan
CHS - MXP
CHSMXP
Charleston
Wed 5/6
11:24 am-8:40 am
2 stops39h 16m
Milan Malpensa
Tue 5/12
2:55 pm-4:57 pm
2 stops32h 02m
$779
CharlotteMilan
CLT - LIN
CLTLIN
Charlotte Douglas
Mon 4/27
7:59 pm-7:45 pm
2 stops17h 46m
Milan Linate
Fri 5/15
6:40 am-10:06 pm
2 stops21h 26m
$792
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Italy
Have a flexible travel schedule? Discover the best time to fly to Italy from South Carolina with our price prediction graph.
CLT-MXP
CLT-LIN
CLT-FLR
CLT-FCO
CHS-FCO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Italy
USSC-IT0
CLT-MXP
CLT-LIN
CLT-FLR
CLT-FCO
What is the cheapest month to book a flight from South Carolina to Italy?
Currently, October is the cheapest month in which you can book a flight from South Carolina to Italy (average of $192). Flying from South Carolina to Italy in July is currently the most expensive (average of $772). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SC to IT?
Find hourly flight availability from South Carolina to Italy. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 2, 2026.
One of the essential ways to save on airfare from South Carolina to Italy is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 33% on airfare.
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
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Top regions
Alternative routes for South Carolina to Italy
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Italy by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Italy by cabin class
Find flights from South Carolina to Italy, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Carolina and Italy flights
Browse other South Carolina and Italy flight options. Last updated on April 2, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Italy
Find the right flight back to South Carolina after your stay in Italy
South Carolina to Italy flights
Consider these flights traveling from South Carolina to Italy.
Fly to Italy regions
Consider these flights traveling to Italy regions.
Top 6 airlines flying from South Carolina to Italy
Discover the top 6 airlines that operate flights from South Carolina to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$307 | Average$1,082 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$503 | Average$1,094 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$507 | Average$1,012 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$609 | Average$872 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$699 | Average$1,211 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$745 | Average$1,379 | FlexibilityNo cancel fee | On-time76% |