Italy

$270+ Cheap flights from South Carolina to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/22. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — NAP
Jul 18 — Jul 251
We work with more than 300 partners to bring you better travel deals

Find cheap flights from South Carolina to Italy with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from South Carolina to Italy

Cheapest flights from South Carolina to Italy
Explore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 18, 2026.

This lol.travel deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/311:45 am
CLT
-
MXP
1 stop15h 20m
Finnair
Wed 8/1911:00 am
MXP
-
CLT
1 stop14h 19m
Finnair
Deal found 6/15$677
This FlightHub deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:50 pm
CLT
-
MXP
1 stop11h 45m
Multiple Airlines
Wed 11/181:05 pm
MXP
-
CLT
1 stop33h 14m
Multiple Airlines
Deal found 6/13$702
This United Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/81:00 pm
CLT
-
MXP
1 stop12h 30m
United Airlines
Wed 11/181:05 pm
MXP
-
CLT
2 stops30h 59m
United Airlines
Deal found 6/13$707
This FlightHub deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/89:20 am
CLT
-
MXP
2 stops18h 45m
Air Canada
Wed 11/181:05 pm
MXP
-
CLT
2 stops38h 18m
Air Canada
Deal found 6/13$710
This lol.travel deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/93:40 pm
CLT
-
VCE
1 stop11h 50m
Air Canada
Tue 8/2512:20 pm
VCE
-
CLT
2 stops38h 37m
Air Canada
Deal found 6/14$710
This Ticket deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ticket is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/31:05 pm
CLT
-
VCE
1 stop15h 50m
Multiple Airlines
Wed 8/196:25 am
VCE
-
CLT
1 stop15h 55m
Multiple Airlines
Deal found 6/15$724
This British Airways deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/191:02 pm
CLT
-
FLR
2 stops16h 33m
Multiple Airlines
Wed 8/267:05 am
FLR
-
CLT
2 stops18h 14m
Multiple Airlines
Deal found 6/16$726
This eDestinos deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2512:00 pm
CLT
-
MXP
1 stop15h 05m
Iberia
Tue 9/811:00 am
MXP
-
CLT
1 stop12h 42m
Iberia
Deal found 6/16$726
This United Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1610:40 am
CLT
-
MXP
1 stop20h 25m
United Airlines
Thu 11/199:45 am
MXP
-
CLT
1 stop17h 48m
United Airlines
Deal found 6/13$727
This Trip.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/39:15 am
CLT
-
MXP
2 stops19h 05m
Air Canada
Wed 8/1912:20 pm
MXP
-
CLT
2 stops32h 42m
Air Canada
Deal found 6/15$736
This United Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/610:23 am
CLT
-
LIN
2 stops19h 57m
United Airlines
Thu 12/102:45 pm
LIN
-
CLT
2 stops31h 34m
United Airlines
Deal found 6/14$738
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:00 pm
CLT
-
MXP
1 stop13h 25m
American Airlines
Wed 10/2111:05 am
MXP
-
CLT
1 stop12h 58m
American Airlines
Deal found 6/16$739

Find flight deals from South Carolina to Italy

Keep the following information in mind while searching for South Carolina to Italy flight deals. Data was last updated June 18, 2026.

Most accurate provider

Ovago
3 stars

Most trusted provider

Ovago
3 stars

Round-trip from

$674
(lol.travel)

One-way from

$270
(Ovago)

Popular in

July

Cheapest in

January

Average price

$2,290
Provider with most accurate pricing for Myrtle Beach Intl-Rome (ROM) flight deals.
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Rome (ROM) flights.
From South Carolina to Italy
One-way flight from South Carolina to Italy
Highest demand for flights based on searches. 33% potential increase in price ($651 potential increase over avg. RT price).
Cheapest flight prices on average. 12% potential price decrease ($141 potential savings vs. average RT price).
Average for round-trip flights in June 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 18, 2026.
Use the filters below to find and compare flights from South Carolina to Italy that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteFlorence

CLT - FLR

CLTFLR

Charlotte Douglas

Tue 8/11

1:02 pm-11:35 am

2 stops16h 33m

Florence Peretola

Fri 8/21

7:05 am-7:13 pm

2 stops18h 08m

$726

CharlotteFlorence

CLT - FLR

CLTFLR

Charlotte Douglas

Wed 8/19

1:02 pm-11:35 am

2 stops16h 33m

Florence Peretola

Wed 8/26

7:05 am-7:19 pm

2 stops18h 14m

$726

CharlotteMilan

CLT - MXP

CLTMXP

Charlotte Douglas

Mon 8/3

6:40 pm-1:20 pm

1 stop12h 40m

Milan Malpensa

Wed 8/19

8:45 am-4:45 pm

1 stop14h 00m

$756

CharlotteMilan

CLT - MXP

CLTMXP

Charlotte Douglas

Mon 8/3

10:27 am-7:30 am

2 stops15h 03m

Milan Malpensa

Wed 8/19

9:00 am-9:46 pm

2 stops18h 46m

$760

CharlotteMilan

CLT - LIN

CLTLIN

Charlotte Douglas

Mon 7/20

6:40 pm-1:00 pm

1 stop12h 20m

Milan Linate

Thu 8/20

9:50 am-4:45 pm

1 stop12h 55m

$765

CharlotteMilan

CLT - MXP

CLTMXP

Charlotte Douglas

Wed 8/12

5:30 am-9:25 am

1 stop21h 55m

Milan Malpensa

Wed 11/11

12:00 pm-10:09 pm

1 stop16h 09m

$765

CharlotteMilan

CLT - MXP

CLTMXP

Charlotte Douglas

Tue 7/21

1:06 pm-1:20 pm

1 stop18h 14m

Milan Malpensa

Fri 8/21

9:00 am-11:59 pm

2 stops20h 59m

$767

CharlotteMilan

CLT - MXP

CLTMXP

Charlotte Douglas

Wed 7/22

8:05 am-10:20 am

2 stops20h 15m

Milan Malpensa

Thu 8/20

8:35 am-6:56 pm

2 stops16h 21m

$772

CharlotteFlorence

CLT - FLR

CLTFLR

Charlotte Douglas

Tue 8/18

1:02 pm-11:35 am

2 stops16h 33m

Florence Peretola

Tue 8/25

7:05 am-6:36 pm

2 stops17h 31m

$775

CharlotteMilan

CLT - LIN

CLTLIN

Charlotte Douglas

Tue 7/21

9:40 am-8:50 am

2 stops17h 10m

Milan Linate

Thu 8/20

6:40 am-4:07 pm

2 stops15h 27m

$776

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/13

Showing 1-10 of 60 resultsSorted by cheapest first
1
2
3
...
6

Best time to book a flight from South Carolina to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Italy

What is the cheapest month to book a flight from South Carolina to Italy?

Currently, September is the cheapest month in which you can book a flight from South Carolina to Italy (average of $147). Flying from South Carolina to Italy in July is currently the most expensive (average of $715). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How far ahead should I book a flight from South Carolina to Italy?

The price you pay for your flight from South Carolina to Italy may vary depending on when you book. For the best chance of a lower fare, look to book 40 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from South Carolina to Italy?

    For as low as $765, Air Canada can have you in Italy from South Carolina in 12h 20m. The distance from South Carolina to Italy is about 4548 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from South Carolina to Italy that include hotel bookings?

    Yes. In addition to deals on South Carolina to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Italy.

  • Can I find deals for business class flights from South Carolina to Italy?

    Yes. Cheapflights offers flight deals from South Carolina to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Italy?

    Currently, September is the cheapest month in which you can book a flight from South Carolina to Italy (average of $147). Flying from South Carolina to Italy in July is currently the most expensive (average of $715). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Italy

See prices for flight routes from nearby airports that may be better suited for you.

Top 6 airlines flying from South Carolina to Italy

Discover the top 6 airlines that operate flights from South Carolina to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 18, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$457Average$1,188FlexibilityNo cancel feeOn-timeN/A
British AirwaysCheapest$468Average$983FlexibilityNo cancel feeOn-time70%
LufthansaCheapest$497Average$1,362FlexibilityNo cancel feeOn-time76%
United AirlinesCheapest$575Average$1,160FlexibilityNo cancel feeOn-time69%
KLMCheapest$625Average$945FlexibilityNo cancel feeOn-time75%
American AirlinesCheapest$765Average$1,331FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.