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Italy

$256+ Cheap flights from South Carolina to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/30. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — NAP
Apr 2 — Apr 91
Do 4/2
Do 4/9
1 adult, Economy
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Cheap flight deals from South Carolina to Italy

Cheapest flights from South Carolina to Italy
Explore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on März 3, 2026.

This United Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mo 8/106:00 am
CLT
-
VCE
1 stop19h 55m
United Airlines
Do 8/2012:20 pm
VCE
-
CLT
2 stops35h 24m
United Airlines
Deal found 2/27$493
This United Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 4/142:58 pm
CHS
-
MXP
2 stops37h 22m
United Airlines
Di 4/2112:20 pm
MXP
-
CHS
2 stops41h 39m
United Airlines
Deal found 2/28$496
This United Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 8/116:00 am
CLT
-
VCE
1 stop19h 55m
United Airlines
Fr 8/2112:20 pm
VCE
-
CLT
2 stops31h 30m
United Airlines
Deal found 2/27$498
This Booking.com deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 4/147:40 pm
CHS
-
MXP
2 stops32h 40m
Air Canada
Di 4/2112:20 pm
MXP
-
CHS
2 stops36h 39m
Air Canada
Deal found 2/28$501
This United Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 8/126:00 am
CLT
-
MXP
2 stops28h 40m
United Airlines
Mi 8/2612:20 pm
MXP
-
CLT
2 stops39h 03m
United Airlines
Deal found 2/26$505
This United Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
So 8/96:15 am
CLT
-
VCE
2 stops23h 25m
United Airlines
Fr 8/216:20 am
VCE
-
CLT
2 stops37h 30m
United Airlines
Deal found 2/26$505
This American Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mo 8/106:00 pm
CLT
-
VCE
1 stop13h 50m
American Airlines
Do 8/2012:15 pm
VCE
-
CLT
1 stop18h 04m
American Airlines
Deal found 2/27$506
This United Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mo 3/91:52 pm
CLT
-
MXP
1 stop12h 38m
United Airlines
Di 3/1712:05 pm
MXP
-
CLT
2 stops38h 10m
United Airlines
Deal found 2/27$507
This oojo deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 8/186:00 pm
CLT
-
LIN
1 stop13h 30m
British Airways
Di 8/2511:10 am
LIN
-
CLT
1 stop13h 55m
British Airways
Deal found 2/25$508
This American Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 8/188:15 pm
CLT
-
MXP
1 stop15h 35m
American Airlines
Di 8/258:30 am
MXP
-
CLT
1 stop16h 35m
American Airlines
Deal found 2/26$508
This Mytrip deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 4/166:30 am
CHS
-
MXP
2 stops21h 50m
Air Canada
Do 4/2312:20 pm
MXP
-
CHS
2 stops27h 53m
Air Canada
Deal found 3/1$509
This United Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 3/310:30 am
CLT
-
MXP
2 stops17h 25m
United Airlines
Di 3/1012:05 pm
MXP
-
CLT
2 stops38h 10m
United Airlines
Deal found 3/2$510

Find flight deals from South Carolina to Italy

Keep the following information in mind while searching for South Carolina to Italy flight deals. Data was last updated März 3, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$496
(United Airlines)

One-way from

$256
(Kiwi.com)

Popular in

June

Cheapest in

January

Average price

$916
Provider with most accurate pricing for Myrtle Beach Intl-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Rome (ROM) flights.
Search Deals
From South Carolina to Italy
Search Deals
One-way flight from South Carolina to Italy
Search Deals
Highest demand for flights based on searches. 30% potential increase in price ($487 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 9% potential price decrease ($94 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated März 3, 2026.
Use the filters below to find and compare flights from South Carolina to Italy that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteMilan

CLT - MXP

CLTMXP

Charlotte Douglas

Di 4/7

10:34 am-1:20 pm

1 stop20h 46m

Milan Malpensa

Do 4/23

9:00 am-11:57 pm

2 stops20h 57m

$547

CharlestonMilan

CHS - MXP

CHSMXP

Charleston

Mo 4/13

5:00 pm-1:20 pm

1 stop14h 20m

Milan Malpensa

Mo 4/20

9:00 am-12:25 pm

2 stops33h 25m

$564

CharlotteMilan

CLT - LIN

CLTLIN

Charlotte Douglas

Mi 4/22

12:40 pm-12:00 pm

2 stops17h 20m

Milan Linate

Do 5/7

6:40 am-8:14 pm

2 stops19h 34m

$571

CharlestonMilan

CHS - MXP

CHSMXP

Charleston

Mo 4/13

12:04 pm-12:05 pm

1 stop18h 01m

Milan Malpensa

Mo 4/20

11:40 am-8:41 pm

1 stop15h 01m

$571

CharlotteMilan

CLT - LIN

CLTLIN

Charlotte Douglas

Mo 3/30

11:23 am-8:50 am

2 stops15h 27m

Milan Linate

Do 4/23

6:25 am-5:09 pm

2 stops16h 44m

$573

CharlotteMilan

CLT - LIN

CLTLIN

Charlotte Douglas

Di 3/31

11:23 am-8:50 am

2 stops15h 27m

Milan Linate

Do 4/23

6:25 am-5:09 pm

2 stops16h 44m

$573

CharlotteMilan

CLT - MXP

CLTMXP

Charlotte Douglas

Do 3/5

8:18 am-8:05 am

1 stop17h 47m

Milan Malpensa

Do 3/12

10:25 am-9:43 pm

1 stop16h 18m

$577

CharlotteMilan

CLT - MXP

CLTMXP

Charlotte Douglas

Mo 3/30

10:13 am-10:20 am

2 stops18h 07m

Milan Malpensa

Mi 4/29

9:45 am-4:23 pm

1 stop12h 38m

$585

CharlotteNaples

CLT - NAP

CLTNAP

Charlotte Douglas

Di 4/14

5:12 pm-2:15 pm

2 stops15h 03m

Naples

Mi 4/22

10:40 am-9:28 pm

2 stops16h 48m

$586

CharlotteMilan

CLT - LIN

CLTLIN

Charlotte Douglas

Di 5/5

10:55 am-8:50 am

2 stops15h 55m

Milan Linate

Mi 5/13

6:40 am-6:19 pm

2 stops17h 39m

$593

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/27

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from South Carolina to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Italy

What is the cheapest month to book a flight from South Carolina to Italy?

Currently, October is the cheapest month in which you can book a flight from South Carolina to Italy (average of $192). Flying from South Carolina to Italy in July is currently the most expensive (average of $783). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to IT?

Find hourly flight availability from South Carolina to Italy. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated März 3, 2026.

One of the essential ways to save on airfare from South Carolina to Italy is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 33% on airfare.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Italy?

    For as low as $571, United Airlines can have you in Italy from South Carolina in 17h 20m. The distance from South Carolina to Italy is about 4548 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from South Carolina to Italy that include hotel bookings?

    Yes. In addition to deals on South Carolina to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Italy.

  • Can I find deals for business class flights from South Carolina to Italy?

    Yes. Cheapflights offers flight deals from South Carolina to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Italy?

    Currently, October is the cheapest month in which you can book a flight from South Carolina to Italy (average of $192). Flying from South Carolina to Italy in July is currently the most expensive (average of $783). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Italy

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from South Carolina to Italy

Discover the top 6 airlines that operate flights from South Carolina to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated März 3, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$307Average$1,052FlexibilityNo cancel feeOn-time69%
British AirwaysCheapest$468Average$894FlexibilityNo cancel feeOn-time70%
DeltaCheapest$503Average$1,130FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$503Average$1,134FlexibilityNo cancel feeOn-time71%
KLMCheapest$507Average$1,012FlexibilityNo cancel feeOn-time75%
LufthansaCheapest$591Average$1,095FlexibilityNo cancel feeOn-time76%

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