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Italy

$344+ Cheap flights from South Carolina to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/27. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — NAP
May 28 — Jun 41
Thu 5/28
Thu 6/4
1 adult, Economy
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Cheap flight deals from South Carolina to Italy

Cheapest flights from South Carolina to Italy
Explore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 28, 2026.

This CrystalTravel deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CrystalTravel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:40 pm
CLT
-
VCE
1 stop15h 55m
Lufthansa
Wed 8/196:30 am
VCE
-
CLT
1 stop16h 15m
Lufthansa
Deal found 4/25$683
This eDestinos deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2512:00 pm
CLT
-
MXP
1 stop15h 05m
Iberia
Tue 9/811:05 am
MXP
-
CLT
1 stop12h 37m
Iberia
Deal found 4/23$686
This lol.travel deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/123:40 pm
CLT
-
LIN
2 stops15h 20m
Multiple Airlines
Wed 8/2610:35 am
LIN
-
CLT
2 stops16h 22m
Multiple Airlines
Deal found 4/25$692
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/117:00 am
CLT
-
VCE
1 stop20h 05m
United Airlines
Thu 8/2012:20 pm
VCE
-
CLT
2 stops37h 54m
United Airlines
Deal found 4/27$693
This Gotogate deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/129:20 am
CLT
-
VCE
2 stops21h 25m
Multiple Airlines
Wed 8/191:25 pm
VCE
-
CLT
1 stop33h 20m
Multiple Airlines
Deal found 4/28$694
This Cheapflightsfares deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:05 am
CLT
-
VCE
2 stops19h 30m
SWISS
Wed 8/197:40 pm
VCE
-
CLT
2 stops27h 05m
SWISS
Deal found 4/28$702
This Cheapflightsfares deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:40 pm
CLT
-
VCE
1 stop12h 05m
Lufthansa
Thu 8/209:55 am
VCE
-
CLT
1 stop12h 50m
Lufthansa
Deal found 4/28$704
This Cheapflightsfares deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:50 pm
CLT
-
VCE
2 stops17h 35m
SWISS
Tue 12/89:40 am
VCE
-
CLT
2 stops17h 43m
SWISS
Deal found 4/25$706
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:40 pm
CLT
-
MXP
1 stop16h 00m
United Airlines
Wed 8/2612:20 pm
MXP
-
CLT
2 stops35h 24m
United Airlines
Deal found 4/25$710
This Cheapflightsfares deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:50 pm
CLT
-
VCE
1 stop11h 55m
Lufthansa
Tue 12/82:50 pm
VCE
-
CLT
2 stops16h 00m
Lufthansa
Deal found 4/25$712
This Cheapflightsfares deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:40 pm
CLT
-
MXP
2 stops13h 20m
SWISS
Tue 8/187:25 pm
MXP
-
CLT
2 stops27h 20m
SWISS
Deal found 4/24$714
This Gotogate deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/99:20 am
CLT
-
MXP
2 stops19h 00m
Multiple Airlines
Tue 8/185:20 pm
MXP
-
CLT
1 stop29h 25m
Multiple Airlines
Deal found 4/25$717

Find flight deals from South Carolina to Italy

Keep the following information in mind while searching for South Carolina to Italy flight deals. Data was last updated April 28, 2026.

Most accurate provider

Ovago
3 stars

Most trusted provider

Ovago
3 stars

Round-trip from

$683
(CrystalTravel)

One-way from

$344
(Kiwi.com)

Popular in

June

Cheapest in

January

Average price

$1,216
Provider with most accurate pricing for Myrtle Beach Intl-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Rome (ROM) flights.
Search Deals
From South Carolina to Italy
Search Deals
One-way flight from South Carolina to Italy
Search Deals
Highest demand for flights based on searches. 28% potential increase in price ($459 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 9% potential price decrease ($98 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
Use the filters below to find and compare flights from South Carolina to Italy that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteMilan

CLT - MXP

CLTMXP

Charlotte Douglas

Tue 5/5

11:26 am-7:30 am

1 stop14h 04m

Milan Malpensa

Tue 5/12

9:45 am-4:23 pm

1 stop12h 38m

$772

CharlotteMilan

CLT - MXP

CLTMXP

Charlotte Douglas

Tue 5/5

11:26 am-7:30 am

1 stop14h 04m

Milan Malpensa

Thu 5/14

9:45 am-4:23 pm

1 stop12h 38m

$772

CharlotteMilan

CLT - LIN

CLTLIN

Charlotte Douglas

Tue 5/5

2:50 pm-12:20 pm

2 stops15h 30m

Milan Linate

Tue 5/12

10:35 am-9:09 pm

2 stops16h 34m

$788

CharlotteMilan

CLT - LIN

CLTLIN

Charlotte Douglas

Mon 5/11

2:50 pm-2:40 pm

2 stops17h 50m

Milan Linate

Tue 5/19

6:50 am-6:55 pm

2 stops18h 05m

$801

CharlestonMilan

CHS - MXP

CHSMXP

Charleston

Fri 10/2

11:05 am-5:45 pm

2 stops24h 40m

Milan Malpensa

Sat 10/17

3:15 pm-7:30 pm

2 stops58h 15m

$840

CharlestonRome

CHS - FCO

CHSFCO

Charleston

Fri 9/25

11:05 am-6:25 pm

2 stops25h 20m

Rome Fiumicino

Sun 10/4

10:45 am-10:15 am

2 stops29h 30m

$855

CharlestonRome

CHS - FCO

CHSFCO

Charleston

Wed 10/14

4:30 pm-12:40 pm

1 stop14h 10m

Rome Fiumicino

Thu 10/22

6:30 am-6:03 pm

2 stops17h 33m

$858

CharlotteMilan

CLT - MXP

CLTMXP

Charlotte Douglas

Tue 5/26

8:05 am-1:20 pm

1 stop23h 15m

Milan Malpensa

Wed 6/3

12:20 pm-2:12 pm

2 stops31h 52m

$882

CharlotteNaples

CLT - NAP

CLTNAP

Charlotte Douglas

Mon 10/12

7:05 pm-7:05 am

1 stop30h 00m

Naples

Sat 10/24

6:05 am-10:16 pm

2 stops22h 11m

$890

CharlestonMilan

CHS - MXP

CHSMXP

Charleston

Wed 9/9

11:05 am-2:10 pm

2 stops45h 05m

Milan Malpensa

Sat 9/19

7:45 pm-10:15 am

2 stops20h 30m

$903

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/27

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from South Carolina to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Italy

How far ahead should I book a flight from South Carolina to Italy?

The price you pay for your flight from South Carolina to Italy may vary depending on when you book. For the best chance of a lower fare, look to book 42 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from South Carolina to Italy?

Currently, June is the cheapest month in which you can book a flight from South Carolina to Italy (average of $95). Flying from South Carolina to Italy in July is currently the most expensive (average of $715). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Italy?

    For as low as $772, United Airlines can have you in Italy from South Carolina in 14h 04m. The distance from South Carolina to Italy is about 4519 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from South Carolina to Italy that include hotel bookings?

    Yes. In addition to deals on South Carolina to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Italy.

  • Can I find deals for business class flights from South Carolina to Italy?

    Yes. Cheapflights offers flight deals from South Carolina to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Italy?

    Currently, June is the cheapest month in which you can book a flight from South Carolina to Italy (average of $95). Flying from South Carolina to Italy in July is currently the most expensive (average of $715). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Italy

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from South Carolina to Italy

Discover the top 6 airlines that operate flights from South Carolina to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$307Average$1,073FlexibilityNo cancel feeOn-time69%
British AirwaysCheapest$468Average$882FlexibilityNo cancel feeOn-time70%
DeltaCheapest$511Average$1,112FlexibilityNo cancel feeOn-timeN/A
KLMCheapest$625Average$945FlexibilityNo cancel feeOn-time75%
American AirlinesCheapest$699Average$1,182FlexibilityNo cancel feeOn-time71%
LufthansaCheapest$745Average$1,398FlexibilityNo cancel feeOn-time76%

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