Italy

$301+ Cheap flights from South Carolina to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/8. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — NAP
Jul 24 — Jul 311
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Cheap flight deals from South Carolina to Italy

Cheapest flights from South Carolina to Italy
Explore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 24, 2026.

This British Airways deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/101:56 pm
CLT
-
FLR
2 stops15h 24m
Multiple Airlines
Tue 11/248:30 pm
FLR
-
CLT
1 stop24h 00m
Multiple Airlines
Deal found 6/20$689
This oojo deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:50 pm
CLT
-
VCE
1 stop11h 55m
Lufthansa
Tue 12/88:00 am
VCE
-
CLT
1 stop14h 55m
Lufthansa
Deal found 6/24$701
This Gotogate deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:50 pm
CLT
-
MXP
1 stop11h 45m
Multiple Airlines
Wed 12/161:05 pm
MXP
-
CLT
2 stops33h 14m
Multiple Airlines
Deal found 6/21$702
This Cheapflightsfares deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:50 pm
CLT
-
VCE
1 stop11h 30m
Lufthansa
Tue 12/88:00 am
VCE
-
CLT
1 stop14h 55m
Lufthansa
Deal found 6/22$703
This FlightHub deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/710:23 am
CLT
-
MXP
2 stops17h 42m
Air Canada
Wed 12/161:05 pm
MXP
-
CLT
2 stops34h 02m
Air Canada
Deal found 6/21$710
This Delta deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/11:15 pm
CLT
-
VCE
2 stops15h 55m
Delta
Tue 12/86:30 am
VCE
-
CLT
2 stops21h 36m
Delta
Deal found 6/24$720
This oojo deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:50 pm
CLT
-
MXP
1 stop11h 45m
Lufthansa
Wed 12/161:20 pm
MXP
-
CLT
1 stop33h 35m
Lufthansa
Deal found 6/21$723
This British Airways deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/181:02 pm
CLT
-
FLR
2 stops16h 33m
Multiple Airlines
Tue 8/257:05 am
FLR
-
CLT
2 stops17h 31m
Multiple Airlines
Deal found 6/23$725
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:40 pm
CLT
-
MXP
1 stop11h 35m
Multiple Airlines
Tue 8/2510:40 am
MXP
-
CLT
2 stops17h 01m
Multiple Airlines
Deal found 6/24$725
This Flighttix deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/310:27 am
CLT
-
MXP
2 stops17h 53m
Air Canada
Wed 8/1912:20 pm
MXP
-
CLT
2 stops17h 39m
Air Canada
Deal found 6/20$726
This American Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:25 pm
CLT
-
LIN
1 stop14h 05m
American Airlines
Wed 12/167:35 am
LIN
-
CLT
1 stop14h 30m
American Airlines
Deal found 6/21$729
This Gotogate deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/36:40 pm
CLT
-
LIN
1 stop12h 20m
Lufthansa
Wed 8/199:50 am
LIN
-
CLT
1 stop12h 55m
Lufthansa
Deal found 6/20$735

Find flight deals from South Carolina to Italy

Keep the following information in mind while searching for South Carolina to Italy flight deals. Data was last updated June 24, 2026.

Most accurate provider

Ovago
3 stars

Most trusted provider

Ovago
3 stars

Round-trip from

$689
(British Airways)

One-way from

$301
(Kiwi.com)

Popular in

July

Cheapest in

January

Average price

$2,290
Provider with most accurate pricing for Myrtle Beach Intl-Rome (ROM) flight deals.
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Rome (ROM) flights.
From South Carolina to Italy
One-way flight from South Carolina to Italy
Highest demand for flights based on searches. 33% potential increase in price ($651 potential increase over avg. RT price).
Cheapest flight prices on average. 12% potential price decrease ($141 potential savings vs. average RT price).
Average for round-trip flights in June 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 24, 2026.
Use the filters below to find and compare flights from South Carolina to Italy that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteVenice

CLT - VCE

CLTVCE

Charlotte Douglas

Mon 8/3

10:27 am-9:05 am

2 stops16h 38m

Venice Marco Polo

Wed 8/19

9:55 am-4:45 pm

1 stop12h 50m

$763

CharlotteMilan

CLT - MXP

CLTMXP

Charlotte Douglas

Mon 8/10

8:05 am-7:30 am

2 stops17h 25m

Milan Malpensa

Tue 8/25

9:00 am-9:41 pm

2 stops18h 41m

$771

CharlotteFlorence

CLT - FLR

CLTFLR

Charlotte Douglas

Wed 8/19

1:02 pm-11:35 am

2 stops16h 33m

Florence Peretola

Wed 8/26

7:05 am-7:19 pm

2 stops18h 14m

$774

CharlotteFlorence

CLT - FLR

CLTFLR

Charlotte Douglas

Tue 8/18

1:02 pm-11:35 am

2 stops16h 33m

Florence Peretola

Tue 8/25

7:05 am-6:36 pm

2 stops17h 31m

$774

CharlotteFlorence

CLT - FLR

CLTFLR

Charlotte Douglas

Tue 8/11

1:02 pm-11:35 am

2 stops16h 33m

Florence Peretola

Fri 8/21

7:05 am-7:13 pm

2 stops18h 08m

$775

CharlotteMilan

CLT - LIN

CLTLIN

Charlotte Douglas

Mon 8/10

2:53 pm-12:20 pm

2 stops15h 27m

Milan Linate

Tue 8/25

10:35 am-6:56 pm

2 stops14h 21m

$778

CharlestonRome

CHS - FCO

CHSFCO

Charleston

Sun 8/16

7:51 pm-1:15 pm

1 stop11h 24m

Rome Fiumicino

Wed 8/26

2:20 pm-9:34 pm

2 stops37h 14m

$804

CharlotteNaples

CLT - NAP

CLTNAP

Charlotte Douglas

Sun 8/2

6:00 am-11:40 am

2 stops23h 40m

Naples

Tue 8/18

1:05 pm-4:45 pm

1 stop33h 40m

$819

CharlotteNaples

CLT - NAP

CLTNAP

Charlotte Douglas

Wed 8/12

10:25 am-9:40 am

2 stops17h 15m

Naples

Tue 8/18

1:05 pm-4:45 pm

1 stop33h 40m

$827

CharlotteVenice

CLT - VCE

CLTVCE

Charlotte Douglas

Sat 8/22

5:58 pm-9:05 am

1 stop33h 07m

Venice Marco Polo

Sun 8/30

9:55 am-4:45 pm

1 stop12h 50m

$829

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/22

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from South Carolina to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Italy

What is the cheapest month to book a flight from South Carolina to Italy?

Currently, September is the cheapest month in which you can book a flight from South Carolina to Italy (average of $147). Flying from South Carolina to Italy in July is currently the most expensive (average of $715). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How far ahead should I book a flight from South Carolina to Italy?

The price you pay for your flight from South Carolina to Italy may vary depending on when you book. For the best chance of a lower fare, look to book 43 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from South Carolina to Italy?

    For as low as $842, United Airlines can have you in Italy from South Carolina in 14h 50m. The distance from South Carolina to Italy is about 4612 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from South Carolina to Italy one-way?

    $314 is the cheapest one-way deal found within the past few days, from Neos Air. You may also be able to find cheap deals on Iberia and Aeromexico, with prices starting from $413 and $444, respectively.

  • Can I find deals for flights from South Carolina to Italy that include hotel bookings?

    Yes. In addition to deals on South Carolina to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Italy.

  • Can I find deals for business class flights from South Carolina to Italy?

    Yes. Cheapflights offers flight deals from South Carolina to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Italy?

    Currently, September is the cheapest month in which you can book a flight from South Carolina to Italy (average of $147). Flying from South Carolina to Italy in July is currently the most expensive (average of $715). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Italy

See prices for flight routes from nearby airports that may be better suited for you.

Top 6 airlines flying from South Carolina to Italy

Discover the top 6 airlines that operate flights from South Carolina to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest$468Average$984FlexibilityNo cancel feeOn-time70%
LufthansaCheapest$497Average$1,362FlexibilityNo cancel feeOn-time76%
DeltaCheapest$503Average$1,203FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$575Average$1,168FlexibilityNo cancel feeOn-time69%
KLMCheapest$625Average$945FlexibilityNo cancel feeOn-time75%
American AirlinesCheapest$765Average$1,334FlexibilityNo cancel feeOn-time71%

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