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$218+ Cheap flights from South Carolina to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/16. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — NAP
dic. 18 — dic. 251
jue. 12/18
jue. 12/25
1 adult, Economy
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Find flight deals from South Carolina to Italy

Cheapest flights from South Carolina to Italy
Explore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on noviembre 18, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/246:50 pmCLT - MXP
1 stop11h 45mLufthansa
mar. 12/99:50 amMXP - CLT
1 stop13h 05mLufthansa
Deal found 11/18$456
This Mytrip deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/249:30 amCLT - MXP
2 stops18h 25mAir Canada
mar. 12/91:05 pmMXP - CLT
2 stops37h 52mAir Canada
Deal found 11/18$473
This Mytrip deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/249:30 amCLT - MXP
2 stops18h 25mMultiple Airlines
mar. 12/99:50 amMXP - CLT
1 stop13h 05mMultiple Airlines
Deal found 11/18$475
This Mytrip deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/235:05 pmCLT - MXP
2 stops34h 50mAir Canada
mar. 12/910:40 amMXP - CLT
2 stops16h 17mAir Canada
Deal found 11/16$477
This Air Canada deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/106:00 amCLT - MXP
2 stops21h 55mAir Canada
mar. 1/131:05 pmMXP - CLT
2 stops35h 54mAir Canada
Deal found 11/16$482
This United Airlines deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/31:55 pmCLT - MXP
1 stop11h 35mUnited Airlines
mar. 12/91:05 pmMXP - CLT
2 stops31h 06mUnited Airlines
Deal found 11/17$483
This Air Canada deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/99:30 amCLT - MXP
2 stops42h 25mAir Canada
mar. 1/131:05 pmMXP - CLT
2 stops35h 54mAir Canada
Deal found 11/16$484
This Air Canada deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/29:30 amCLT - MXP
2 stops42h 25mAir Canada
vie. 12/121:05 pmMXP - CLT
2 stops34h 00mAir Canada
Deal found 11/17$485
This Trip.com deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/1012:59 pmCLT - FCO
2 stops29h 06mMultiple Airlines
lun. 12/156:00 amFCO - CLT
2 stops36h 04mMultiple Airlines
Deal found 11/16$488
This United Airlines deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/317:22 pmSAV - FCO
1 stop31h 08mUnited Airlines
dom. 1/1812:45 pmFCO - SAV
2 stops55h 53mUnited Airlines
Deal found 11/17$490
This lol.travel deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/242:50 pmCLT - LIN
2 stops20h 05mLufthansa
mar. 12/99:45 amLIN - CLT
1 stop13h 10mLufthansa
Deal found 11/17$500
This Cheapflightsfares deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/17:44 pmCLT - LIN
2 stops17h 06mLufthansa
mar. 12/99:45 amLIN - CLT
1 stop13h 10mLufthansa
Deal found 11/17$502

Cheap flight deals from South Carolina to Italy

Keep the following information in mind while searching for South Carolina to Italy flight deals. Data was last updated noviembre 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$448
(Kiwi.com)

One-way from

$218
(American Airlines)

Popular in

June

Cheapest in

November

Average price

$720
Provider with most accurate pricing for Myrtle Beach Intl-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Rome (ROM) flights.
Search Deals
From South Carolina to Italy
Search Deals
One-way flight from South Carolina to Italy
Search Deals
Highest demand for flights based on searches. 27% potential increase in price ($408 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($74 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 18, 2025.
Use the filters below to find and compare flights from South Carolina to Italy that are best for you.

Fly from

South Carolina

Fly to

Italy

Route

Depart

Return

Price

GreenvilleRome

GSP - FCO

GSPFCO

Greenville

mar. 1/13

11:49 am-11:00 am

2 stops17h 11m

Rome Fiumicino

mar. 1/20

10:30 am-11:48 pm

1 stop19h 18m

$448

SavannahRome

SAV - FCO

SAVFCO

Savannah/Hilton Head

sáb. 1/31

2:05 pm-7:55 am

1 stop11h 50m

Rome Fiumicino

lun. 2/9

11:15 am-1:09 pm

2 stops31h 54m

$483

CharlotteMilan

CLT - MXP

CLTMXP

Charlotte Douglas

lun. 12/1

5:35 pm-4:40 pm

2 stops17h 05m

Milan Malpensa

mar. 12/9

1:05 pm-9:59 pm

2 stops38h 54m

$489

SavannahRome

SAV - FCO

SAVFCO

Savannah/Hilton Head

vie. 1/30

2:05 pm-7:55 am

1 stop11h 50m

Rome Fiumicino

dom. 2/8

7:05 am-7:25 pm

2 stops18h 20m

$489

CharlestonRome

CHS - FCO

CHSFCO

Charleston

jue. 1/8

7:45 pm-9:25 am

2 stops31h 40m

Rome Fiumicino

jue. 1/29

12:50 pm-11:48 pm

2 stops40h 58m

$490

CharlestonRome

CHS - FCO

CHSFCO

Charleston

jue. 1/15

4:41 pm-9:25 am

2 stops34h 44m

Rome Fiumicino

jue. 1/29

12:50 pm-2:48 pm

2 stops31h 58m

$490

SavannahRome

SAV - FCO

SAVFCO

Savannah/Hilton Head

vie. 1/30

7:19 pm-8:30 am

1 stop31h 11m

Rome Fiumicino

dom. 2/8

12:45 pm-1:09 pm

2 stops30h 24m

$490

CharlestonRome

CHS - FCO

CHSFCO

Charleston

lun. 1/12

2:58 pm-12:25 pm

2 stops15h 27m

Rome Fiumicino

vie. 1/23

7:05 am-9:17 pm

2 stops20h 12m

$494

SavannahRome

SAV - FCO

SAVFCO

Savannah/Hilton Head

sáb. 1/31

2:13 pm-8:30 am

1 stop12h 17m

Rome Fiumicino

lun. 2/9

11:00 am-7:25 pm

1 stop14h 25m

$495

SavannahRome

SAV - FCO

SAVFCO

Savannah/Hilton Head

vie. 1/30

2:13 pm-9:00 pm

2 stops24h 47m

Rome Fiumicino

dom. 2/8

9:40 am-10:58 pm

2 stops19h 18m

$495

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/17

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Italy

What is the cheapest month to book a flight from South Carolina to Italy?

Currently, October is the cheapest month in which you can book a flight from South Carolina to Italy (average of $181). Flying from South Carolina to Italy in July is currently the most expensive (average of $772). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to IT?

Find hourly flight availability from South Carolina to Italy. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated noviembre 18, 2025.

One of the essential ways to save on airfare from South Carolina to Italy is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 11% on airfare.

What is the cheapest day to fly from South Carolina to Italy?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Italy. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their South Carolina to Italy flight should consider departing on Sunday mornings when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Italy?

    For as low as $483, Lufthansa can have you in Italy from South Carolina in 11h 50m. The distance from South Carolina to Italy is about 4941 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from South Carolina to Italy one-way?

    $222 is the cheapest one-way deal found within the past few days, from British Airways. You may also be able to find cheap deals on KLM and Brussels Airlines, with prices starting from $226 and $367, respectively.

  • Can I find deals for flights from South Carolina to Italy that include hotel bookings?

    Yes. In addition to deals on South Carolina to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Italy.

  • Can I find deals for business class flights from South Carolina to Italy?

    Yes. Cheapflights offers flight deals from South Carolina to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Italy?

    Currently, October is the cheapest month in which you can book a flight from South Carolina to Italy (average of $181). Flying from South Carolina to Italy in July is currently the most expensive (average of $772). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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See prices for flight routes from nearby airports that may be better suited for you.
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Top 7 airlines flying from South Carolina to Italy

Discover the top 7 airlines that operate flights from South Carolina to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$307Average$1,062FlexibilityNo cancel feeOn-time69%
DeltaCheapest$547Average$1,197FlexibilityNo cancel feeOn-timeN/A
KLMCheapest$555Average$1,075FlexibilityNo cancel feeOn-time75%
American AirlinesCheapest$628Average$1,193FlexibilityNo cancel feeOn-time71%
LufthansaCheapest$635Average$1,212FlexibilityNo cancel feeOn-time76%
British AirwaysCheapest$674Average$1,038FlexibilityNo cancel feeOn-time70%
Air FranceCheapest$957Average$1,308FlexibilityNo cancel feeOn-time77%

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