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$230+ Cheap flights from South Carolina to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/24. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — NAP
nov. 27 — dic. 41
jue. 11/27
jue. 12/4
1 adult, Economy
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Find flight deals from South Carolina to Italy

Cheapest flights from South Carolina to Italy
Explore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 28, 2025.

This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/95:35 pmCLT - MXP
1 stop13h 30mUnited Airlines
mar. 11/251:05 pmMXP - CLT
2 stops40h 53mUnited Airlines
Deal found 10/26$483
This Mytrip deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/176:50 pmCLT - MXP
1 stop11h 45mMultiple Airlines
jue. 11/276:05 amMXP - CLT
2 stops20h 52mMultiple Airlines
Deal found 10/28$485
This Mytrip deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/96:50 pmCLT - LIN
1 stop18h 00mMultiple Airlines
mar. 11/256:15 amLIN - CLT
2 stops20h 42mMultiple Airlines
Deal found 10/26$487
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/2510:00 amCLT - MXP
2 stops15h 30mUnited Airlines
mar. 12/21:05 pmMXP - CLT
2 stops34h 15mUnited Airlines
Deal found 10/27$487
This Justfly.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/96:50 pmCLT - MXP
1 stop11h 45mLufthansa
mar. 11/259:50 amMXP - CLT
1 stop13h 05mLufthansa
Deal found 10/26$493
This Cheapflightsfares deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/246:50 pmCLT - MXP
1 stop15h 50mLufthansa
vie. 12/56:05 amMXP - CLT
1 stop16h 50mLufthansa
Deal found 10/28$497
This Air France deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/237:59 pmCLT - MXP
1 stop31h 06mMultiple Airlines
mié. 1/1412:00 pmMXP - CLT
1 stop27h 18mMultiple Airlines
Deal found 10/28$498
This Lufthansa deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/166:50 pmCLT - MXP
1 stop15h 50mLufthansa
vie. 11/286:05 amMXP - CLT
1 stop16h 50mLufthansa
Deal found 10/26$499
This Cheapflightsfares deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/96:50 pmCLT - LIN
1 stop18h 00mLufthansa
mar. 11/259:45 amLIN - CLT
1 stop13h 10mLufthansa
Deal found 10/26$501
This Air Canada deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/166:40 amCLT - MXP
2 stops21h 15mAir Canada
vie. 11/281:05 pmMXP - CLT
2 stops37h 52mAir Canada
Deal found 10/26$502
This Lufthansa deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/166:50 pmCLT - LIN
1 stop18h 00mLufthansa
vie. 11/289:35 amLIN - CLT
1 stop13h 20mLufthansa
Deal found 10/26$504
This Air Canada deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/305:05 pmCLT - MXP
2 stops34h 50mAir Canada
vie. 12/121:05 pmMXP - CLT
2 stops37h 52mAir Canada
Deal found 10/27$504

Cheap flight deals from South Carolina to Italy

Keep the following information in mind while searching for South Carolina to Italy flight deals. Data was last updated octubre 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$483
(United Airlines)

One-way from

$230
(Kiwi.com)

Popular in

June

Cheapest in

November

Average price

$925
Provider with most accurate pricing for Myrtle Beach Intl-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Rome (ROM) flights.
Search Deals
From South Carolina to Italy
Search Deals
One-way flight from South Carolina to Italy
Search Deals
Highest demand for flights based on searches. 27% potential increase in price ($418 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($77 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 28, 2025.
Use the filters below to find and compare flights from South Carolina to Italy that are best for you.

Fly from

South Carolina

Fly to

Italy

Route

Depart

Return

Price

CharlotteMilan

CLT - MXP

CLTMXP

Charlotte Douglas

lun. 11/17

5:35 pm-1:05 pm

1 stop13h 30m

Milan Malpensa

jue. 11/27

1:05 pm-2:09 pm

2 stops31h 04m

$483

CharlotteMilan

CLT - MXP

CLTMXP

Charlotte Douglas

lun. 11/24

7:04 am-9:55 am

2 stops20h 51m

Milan Malpensa

vie. 12/5

1:05 pm-9:39 pm

2 stops38h 34m

$483

CharlotteMilan

CLT - MXP

CLTMXP

Charlotte Douglas

mar. 11/25

10:00 am-7:30 am

2 stops15h 30m

Milan Malpensa

mar. 12/2

1:05 pm-5:20 pm

2 stops34h 15m

$487

CharlotteMilan

CLT - MXP

CLTMXP

Charlotte Douglas

mié. 11/26

1:44 pm-7:30 am

1 stop11h 46m

Milan Malpensa

mié. 12/3

11:35 am-4:17 pm

2 stops34h 42m

$502

CharlotteMilan

CLT - LIN

CLTLIN

Charlotte Douglas

dom. 11/16

6:50 pm-6:50 pm

1 stop18h 00m

Milan Linate

vie. 11/28

9:35 am-4:55 pm

1 stop13h 20m

$504

CharlotteMilan

CLT - MXP

CLTMXP

Charlotte Douglas

mié. 12/31

6:00 am-9:55 am

2 stops21h 55m

Milan Malpensa

vie. 1/9

9:45 am-4:39 pm

1 stop12h 54m

$506

CharlotteMilan

CLT - MXP

CLTMXP

Charlotte Douglas

lun. 12/1

7:04 am-9:55 am

2 stops20h 51m

Milan Malpensa

lun. 12/8

1:20 pm-4:55 pm

1 stop33h 35m

$507

CharlotteMilan

CLT - LIN

CLTLIN

Charlotte Douglas

mié. 1/14

8:25 pm-5:45 pm

1 stop15h 20m

Milan Linate

lun. 1/19

6:55 pm-2:15 pm

1 stop25h 20m

$510

CharlotteMilan

CLT - LIN

CLTLIN

Charlotte Douglas

lun. 11/17

6:50 pm-6:50 pm

1 stop18h 00m

Milan Linate

jue. 11/27

7:40 pm-4:55 pm

1 stop27h 15m

$514

CharlotteMilan

CLT - MXP

CLTMXP

Charlotte Douglas

sáb. 11/15

6:45 pm-9:45 am

1 stop33h 00m

Milan Malpensa

jue. 11/27

12:00 pm-10:07 am

2 stops28h 07m

$515

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Italy

What is the cheapest month to book a flight from South Carolina to Italy?

Currently, October is the cheapest month in which you can book a flight from South Carolina to Italy (average of $181). Flying from South Carolina to Italy in July is currently the most expensive (average of $772). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to IT?

Find hourly flight availability from South Carolina to Italy. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated octubre 28, 2025.

One of the essential ways to save on airfare from South Carolina to Italy is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 15% on airfare.

What is the cheapest day to fly from South Carolina to Italy?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Italy. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their South Carolina to Italy flight should consider departing on Sunday mornings when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Italy?

    For as low as $483, United Airlines can have you in Italy from South Carolina in 13h 30m. The distance from South Carolina to Italy is about 4519 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from South Carolina to Italy one-way?

    $298 is the cheapest one-way deal found within the past few days, from Air Canada. You may also be able to find cheap deals on Brussels Airlines and Lufthansa, with prices starting from $300 and $305, respectively.

  • Can I find deals for flights from South Carolina to Italy that include hotel bookings?

    Yes. In addition to deals on South Carolina to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Italy.

  • Can I find deals for business class flights from South Carolina to Italy?

    Yes. Cheapflights offers flight deals from South Carolina to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Italy?

    Currently, October is the cheapest month in which you can book a flight from South Carolina to Italy (average of $181). Flying from South Carolina to Italy in July is currently the most expensive (average of $772). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Italy

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from South Carolina to Italy

Discover the top 6 airlines that operate flights from South Carolina to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$307Average$1,070FlexibilityNo cancel feeOn-time69%
KLMCheapest$555Average$1,075FlexibilityNo cancel feeOn-time75%
DeltaCheapest$555Average$1,188FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$628Average$1,167FlexibilityNo cancel feeOn-time71%
LufthansaCheapest$635Average$1,625FlexibilityNo cancel feeOn-time76%
British AirwaysCheapest$674Average$1,038FlexibilityNo cancel feeOn-time70%

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