$198+ Cheap flights from South Carolina to Italy
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/26. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — NAP
Aug 29 — Sep 51
Round-trip
1 adult, Economy
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Find cheap flights from South Carolina to Italy with Cheapflights
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Cheapest flights from South Carolina to ItalyExplore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2026.
Explore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2026.
This Expedia deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/21:00 pm
CLT
- MXP
1 stop13h 05m
Iberia
Wed 12/910:25 am
MXP
- CLT
1 stop17h 01m
Iberia
Deal found 7/30![Iberia logo]()
$642
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/211:30 am
CLT
- MXP
2 stops14h 35m
American Airlines
Wed 12/910:25 am
MXP
- CLT
2 stops16h 28m
American Airlines
Deal found 7/30![American Airlines logo]()
$666
This Expedia deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:40 pm
CLT
- MXP
1 stop11h 35m
Multiple Airlines
Fri 11/612:55 pm
MXP
- CLT
2 stops33h 31m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$673
This Gotogate deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:40 pm
CLT
- LIN
1 stop12h 20m
Multiple Airlines
Fri 11/66:25 am
LIN
- CLT
2 stops20h 41m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$682
This Gotogate deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:50 pm
CLT
- LIN
1 stop18h 00m
Multiple Airlines
Wed 11/1810:45 am
LIN
- CLT
2 stops16h 21m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$688
This Expedia deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1912:34 pm
CLT
- MXP
1 stop14h 31m
Iberia
Fri 11/610:25 am
MXP
- CLT
1 stop15h 05m
Iberia
Deal found 7/28![Iberia logo]()
$690
This Expedia deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:40 pm
CLT
- LIN
1 stop17h 05m
Lufthansa
Fri 11/69:45 am
LIN
- CLT
1 stop13h 10m
Lufthansa
Deal found 7/28![Lufthansa logo]()
$694
This Gotogate deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/88:55 am
CLT
- MXP
2 stops19h 10m
Multiple Airlines
Wed 11/185:25 pm
MXP
- CLT
1 stop29h 30m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$697
This Expedia deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:40 pm
CLT
- MXP
1 stop11h 35m
Multiple Airlines
Wed 10/2112:20 pm
MXP
- CLT
2 stops32h 37m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$702
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:40 pm
CHS
- MXP
1 stop30h 50m
United Airlines
Thu 12/109:45 am
MXP
- CHS
1 stop14h 21m
United Airlines
Deal found 7/29![United Airlines logo]()
$711
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/211:05 am
CLT
- MXP
1 stop14h 25m
United Airlines
Fri 12/412:55 pm
MXP
- CLT
2 stops32h 58m
United Airlines
Deal found 7/28![United Airlines logo]()
$711
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:50 pm
CHS
- MXP
2 stops15h 05m
Delta
Thu 12/101:05 pm
MXP
- CHS
1 stop15h 04m
Delta
Deal found 7/28![Delta logo]()
$715
Best flights from South Carolina to ItalyDiscover carefully curated flight deals from South Carolina to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 30, 2026.
Discover carefully curated flight deals from South Carolina to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 30, 2026.
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/21:00 pm
CLT
- MXP
1 stop18h 15m
United Airlines
Fri 11/1312:55 pm
MXP
- CLT
2 stops37h 59m
United Airlines
Deal found 7/27![United Airlines logo]()
$726
This Justfly.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/303:05 pm
CHS
- LIN
2 stops15h 55m
Lufthansa
Wed 10/76:50 am
LIN
- CHS
2 stops23h 09m
Lufthansa
Deal found 7/25![Lufthansa logo]()
$778
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/215:31 pm
CHS
- LIN
2 stops15h 34m
American Airlines
Tue 9/2911:10 am
LIN
- CHS
2 stops17h 55m
American Airlines
Deal found 7/29![American Airlines logo]()
$789
This KLM deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:43 pm
CHS
- FCO
1 stop11h 37m
KLM
Tue 11/2410:25 am
FCO
- CHS
1 stop14h 43m
KLM
Deal found 7/26![KLM logo]()
$795
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/159:50 am
CLT
- LIN
2 stops17h 00m
Delta
Fri 10/236:40 am
LIN
- CLT
2 stops17h 45m
Delta
Deal found 7/29![Delta logo]()
$802
This British Airways deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/201:00 pm
CLT
- FLR
2 stops16h 35m
Multiple Airlines
Wed 10/2812:10 pm
FLR
- CLT
2 stops24h 40m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$817
This British Airways deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:45 pm
CLT
- FCO
Nonstop9h 05m
British Airways
Fri 10/231:30 pm
FCO
- CLT
Nonstop10h 55m
British Airways
Deal found 7/28![British Airways logo]()
$984
This Brussels Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Brussels Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/101:00 pm
CLT
- VCE
3 stops40h 15m
Brussels Airlines
Sun 1/247:15 pm
VCE
- CLT
2 stops29h 33m
Brussels Airlines
Deal found 7/27![Brussels Airlines logo]()
$1,032
This Finnair deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:10 pm
CLT
- FCO
Nonstop9h 10m
Finnair
Tue 9/11:30 pm
FCO
- CLT
Nonstop10h 45m
Finnair
Deal found 7/29![Finnair logo]()
$1,034
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/267:53 pm
CHS
- MXP
2 stops32h 27m
United Airlines
Tue 10/612:20 pm
MXP
- CHS
2 stops32h 40m
United Airlines
Deal found 7/28![United Airlines logo]()
$760
This Lufthansa deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:40 pm
CLT
- LIN
1 stop17h 05m
Lufthansa
Thu 9/179:50 am
LIN
- CLT
1 stop12h 55m
Lufthansa
Deal found 7/27![Lufthansa logo]()
$827
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/214:12 pm
CHS
- MXP
1 stop11h 13m
Delta
Sun 10/49:00 am
MXP
- CHS
1 stop18h 24m
Delta
Deal found 7/28![Delta logo]()
$836
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/215:31 pm
CHS
- LIN
2 stops15h 34m
American Airlines
Sun 10/411:00 am
LIN
- CHS
2 stops16h 56m
American Airlines
Deal found 7/29![American Airlines logo]()
$849
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/151:25 pm
CLT
- MXP
1 stop12h 05m
United Airlines
Fri 10/2312:20 pm
MXP
- CLT
2 stops36h 40m
United Airlines
Deal found 7/25![United Airlines logo]()
$776
This Scandinavian Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Scandinavian Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/192:28 pm
CLT
- NAP
2 stops22h 17m
Scandinavian Airlines
Sat 10/246:05 am
NAP
- CLT
3 stops22h 20m
Scandinavian Airlines
Deal found 7/30![Scandinavian Airlines logo]()
$1,716
This Turkish Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:25 pm
CHS
- FCO
2 stops21h 10m
Multiple Airlines
Fri 10/306:40 am
FCO
- CHS
2 stops32h 19m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$875
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/110:40 am
CLT
- LIN
2 stops16h 10m
Delta
Thu 10/811:00 am
LIN
- CLT
2 stops18h 59m
Delta
Deal found 7/29![Delta logo]()
$842
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3011:05 am
CHS
- MXP
1 stop14h 25m
United Airlines
Wed 10/711:20 am
MXP
- CHS
2 stops28h 42m
United Airlines
Deal found 7/25![United Airlines logo]()
$779
This Turkish Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:25 pm
CHS
- FCO
2 stops20h 30m
Multiple Airlines
Sun 11/811:15 am
FCO
- CHS
2 stops28h 44m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$875
This Lufthansa deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:40 pm
CLT
- LIN
1 stop17h 05m
Lufthansa
Thu 9/179:50 am
LIN
- CLT
1 stop12h 55m
Lufthansa
Deal found 7/27![Lufthansa logo]()
$877
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2111:13 am
CHS
- LIN
2 stops15h 37m
Delta
Sun 10/411:00 am
LIN
- CHS
2 stops16h 24m
Delta
Deal found 7/26![Delta logo]()
$847
This KLM deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/87:44 pm
CLT
- LIN
2 stops14h 11m
KLM
Sun 10/256:30 am
LIN
- CLT
2 stops17h 29m
KLM
Deal found 7/28![KLM logo]()
$1,026
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:30 am
CHS
- FCO
2 stops22h 25m
United Airlines
Thu 11/1911:15 am
FCO
- CHS
2 stops40h 26m
United Airlines
Deal found 7/27![United Airlines logo]()
$784
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:21 pm
CLT
- LIN
2 stops15h 44m
Delta
Fri 10/26:40 am
LIN
- CLT
2 stops18h 00m
Delta
Deal found 7/26![Delta logo]()
$847
This Cheapflightsfares deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1610:19 am
CHS
- LIN
2 stops17h 41m
Lufthansa
Wed 9/3010:35 am
LIN
- CHS
2 stops19h 40m
Lufthansa
Deal found 7/28![Lufthansa logo]()
$941
This Turkish Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3011:08 am
CHS
- FCO
2 stops30h 27m
Multiple Airlines
Tue 10/610:55 am
FCO
- CHS
2 stops29h 24m
Multiple Airlines
Deal found 7/29![Multiple Airlines logo]()
$945
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/710:23 am
CLT
- FLR
2 stops21h 17m
United Airlines
Wed 12/96:30 am
FLR
- CLT
2 stops44h 36m
United Airlines
Deal found 7/28![United Airlines logo]()
$796
This Brussels Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Brussels Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/123:01 pm
CLT
- FLR
3 stops37h 59m
Brussels Airlines
Mon 10/197:00 pm
FLR
- CLT
2 stops30h 00m
Brussels Airlines
Deal found 7/28![Brussels Airlines logo]()
$1,245
This Lufthansa deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:40 pm
CLT
- MXP
1 stop22h 30m
Lufthansa
Thu 9/178:45 am
MXP
- CLT
1 stop14h 00m
Lufthansa
Deal found 7/27![Lufthansa logo]()
$941
This Turkish Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1811:05 am
CHS
- FCO
2 stops54h 30m
Multiple Airlines
Mon 9/287:05 am
FCO
- CHS
2 stops34h 26m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$958
Last-minute flights from South Carolina to ItalyDiscover last-minute flight deals from South Carolina to Italy. Data last updated July 30, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Italy. Data last updated July 30, 2026 and is based on user searches.
This FlightHub deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:40 pm
CLT
- VCE
1 stop12h 05m
Multiple Airlines
Wed 8/1912:20 pm
VCE
- CLT
1 stop32h 39m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$814
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/245:43 pm
CLT
- FCO
1 stop14h 47m
Multiple Airlines
Wed 9/96:40 am
FCO
- CLT
2 stops31h 55m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$734
This FlightHub deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:40 pm
CLT
- MXP
1 stop11h 35m
Multiple Airlines
Thu 9/312:20 pm
MXP
- CLT
1 stop32h 42m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$802
This Cheapflightsfares deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:40 pm
CLT
- LIN
1 stop12h 20m
Lufthansa
Thu 9/39:50 am
LIN
- CLT
1 stop12h 55m
Lufthansa
Deal found 7/26![Lufthansa logo]()
$815
This Cheapflightsfares deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:40 pm
CLT
- MXP
1 stop11h 35m
Lufthansa
Thu 9/312:55 pm
MXP
- CLT
2 stops17h 04m
Lufthansa
Deal found 7/27![Lufthansa logo]()
$821
This eDestinos deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2512:00 pm
CLT
- MXP
1 stop15h 05m
Iberia
Tue 9/811:00 am
MXP
- CLT
1 stop12h 42m
Iberia
Deal found 7/26![Iberia logo]()
$745
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/255:43 pm
CLT
- FCO
1 stop14h 47m
Multiple Airlines
Tue 9/87:15 pm
FCO
- CLT
2 stops43h 20m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$773
This Cheapflightsfares deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:40 pm
CLT
- MXP
2 stops17h 55m
SWISS
Tue 9/110:40 am
MXP
- CLT
2 stops17h 01m
SWISS
Deal found 7/26![SWISS logo]()
$808
This United deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:40 pm
CLT
- MXP
1 stop11h 35m
Multiple Airlines
Tue 9/112:20 pm
MXP
- CLT
2 stops32h 31m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$810
This Cheapflightsfares deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:40 pm
CLT
- MXP
1 stop16h 00m
Lufthansa
Tue 9/16:20 am
MXP
- CLT
1 stop16h 25m
Lufthansa
Deal found 7/26![Lufthansa logo]()
$811
This Cheapflightsfares deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/253:00 pm
CLT
- MXP
2 stops19h 40m
Lufthansa
Tue 9/86:20 am
MXP
- CLT
1 stop16h 25m
Lufthansa
Deal found 7/26![Lufthansa logo]()
$816
This FlightHub deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:40 pm
CLT
- MXP
1 stop16h 00m
Lufthansa
Fri 9/48:45 am
MXP
- CLT
1 stop14h 00m
Lufthansa
Deal found 7/26![Lufthansa logo]()
$823
One-way flights from South Carolina to ItalySearch for one-way flight options from South Carolina to Italy. Find affordable one-way fares based on user searches. Data last updated July 30, 2026.
Search for one-way flight options from South Carolina to Italy. Find affordable one-way fares based on user searches. Data last updated July 30, 2026.
This KAYAK deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/261:45 pm
CLT
- FCO
2 stops14h 55m
Aer Lingus
Deal found 7/27![Aer Lingus logo]()
$198
This Ovago deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/291:00 pm
CLT
- LIN
2 stops17h 05m
Aer Lingus
Deal found 7/25![Aer Lingus logo]()
$215
This Gurufare deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/251:45 pm
CLT
- FCO
2 stops14h 55m
Aer Lingus
Deal found 7/26![Aer Lingus logo]()
$261
This KAYAK deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/151:00 pm
CLT
- LIN
2 stops15h 40m
Aer Lingus
Deal found 7/28![Aer Lingus logo]()
$263
This KAYAK deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/241:02 pm
CLT
- LIN
2 stops15h 38m
Aer Lingus
Deal found 7/26![Aer Lingus logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1510:02 pm
CLT
- MXP
2 stops37h 58m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$286
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1910:02 pm
CLT
- MXP
3 stops42h 58m
Multiple Airlines
Deal found 7/30![Multiple Airlines logo]()
$291
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1810:02 pm
CLT
- FCO
2 stops40h 48m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$304
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1810:02 pm
CLT
- MXP
2 stops35h 48m
Multiple Airlines
Deal found 7/30![Multiple Airlines logo]()
$304
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1110:02 pm
CLT
- FLR
2 stops37h 53m
Multiple Airlines
Deal found 7/30![Multiple Airlines logo]()
$305
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1510:02 pm
CLT
- FCO
2 stops45h 23m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1910:02 pm
CLT
- FCO
2 stops39h 18m
Multiple Airlines
Deal found 7/30![Multiple Airlines logo]()
$310
Find flight deals from South Carolina to Italy
Keep the following information in mind while searching for South Carolina to Italy flight deals. Data was last updated July 30, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $642 (Expedia) |
One-way from | $198 (KAYAK) |
Popular in | July |
Cheapest in | January |
Average price | $2,686 |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2026.
Use the filters below to find and compare flights from South Carolina to Italy that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlotteMilan
CLT - MXP
CLTMXP
Charlotte Douglas
Mon 11/2
1:00 pm-1:15 pm
1 stop18h 15m
Milan Malpensa
Fri 11/13
12:55 pm-8:54 pm
2 stops37h 59m
$726
CharlestonMilan
CHS - MXP
CHSMXP
Charleston
Sat 9/26
7:53 pm-10:20 am
2 stops32h 27m
Milan Malpensa
Tue 10/6
12:20 pm-3:00 pm
2 stops32h 40m
$760
CharlotteMilan
CLT - MXP
CLTMXP
Charlotte Douglas
Thu 10/15
1:25 pm-7:30 am
1 stop12h 05m
Milan Malpensa
Fri 10/23
12:20 pm-7:00 pm
2 stops36h 40m
$776
CharlestonMilan
CHS - LIN
CHSLIN
Charleston
Wed 9/30
3:05 pm-1:00 pm
2 stops15h 55m
Milan Linate
Wed 10/7
6:50 am-11:59 pm
2 stops23h 09m
$778
CharlestonMilan
CHS - MXP
CHSMXP
Charleston
Wed 9/30
11:05 am-7:30 am
1 stop14h 25m
Milan Malpensa
Wed 10/7
11:20 am-10:02 am
2 stops28h 42m
$779
CharlestonRome
CHS - FCO
CHSFCO
Charleston
Sun 11/15
6:30 am-10:55 am
2 stops22h 25m
Rome Fiumicino
Thu 11/19
11:15 am-9:41 pm
2 stops40h 26m
$784
CharlestonMilan
CHS - LIN
CHSLIN
Charleston
Mon 9/21
5:31 pm-3:05 pm
2 stops15h 34m
Milan Linate
Tue 9/29
11:10 am-11:05 pm
2 stops17h 55m
$789
CharlestonRome
CHS - FCO
CHSFCO
Charleston
Mon 11/9
5:43 pm-11:20 am
1 stop11h 37m
Rome Fiumicino
Tue 11/24
10:25 am-7:08 pm
1 stop14h 43m
$795
CharlotteFlorence
CLT - FLR
CLTFLR
Charlotte Douglas
Mon 12/7
10:23 am-1:40 pm
2 stops21h 17m
Florence Peretola
Wed 12/9
6:30 am-9:06 pm
2 stops44h 36m
$796
CharlotteMilan
CLT - LIN
CLTLIN
Charlotte Douglas
Thu 10/15
9:50 am-8:50 am
2 stops17h 00m
Milan Linate
Fri 10/23
6:40 am-6:25 pm
2 stops17h 45m
$802
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Italy
Have a flexible travel schedule? Discover the best time to fly to Italy from South Carolina with our price prediction graph.
CLT-FCO
CLT-MXP
CLT-VCE
CLT-LIN
CHS-LIN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Italy
USSC-IT0
CLT-FCO
CLT-MXP
CLT-VCE
CLT-LIN
What is the cheapest month to book a flight from South Carolina to Italy?
Currently, February is the cheapest month in which you can book a flight from South Carolina to Italy (average of $591). Flying from South Carolina to Italy in June is currently the most expensive (average of $1,506). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from South Carolina to Italy?
The price you pay for your flight from South Carolina to Italy may vary depending on when you book. For the best chance of a lower fare, look to book 33 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for South Carolina to Italy
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Italy by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Italy by cabin class
Find flights from South Carolina to Italy, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Carolina and Italy flights
Browse other South Carolina and Italy flight options. Last updated on July 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Italy
Find the right flight back to South Carolina after your stay in Italy
South Carolina to Italy flights
Consider these flights traveling from South Carolina to Italy.
Fly to Italy regions
Consider these flights traveling to Italy regions.
Top 5 airlines flying from South Carolina to Italy
Discover the top 5 airlines that operate flights from South Carolina to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$457 | Average$1,211 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$497 | Average$1,362 | FlexibilityNo cancel fee | On-time76% | |
| Cheapest$575 | Average$1,168 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$609 | Average$998 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$769 | Average$1,334 | FlexibilityNo cancel fee | On-time71% |