$330+ Cheap flights from South Carolina to Italy
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/22. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — NAP
Dec 5 — Dec 121
Round-trip
1 adult, Economy
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Find cheap flights from South Carolina to Italy with Cheapflights
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Cheapest flights from South Carolina to ItalyExplore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2026.
Explore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2026.
This Booking.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2312:54 pm -
1 stop15h 51m
Tue 12/81:10 pm -
1 stop16h 16m
Deal found 11/3![British Airways logo]()
$677
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/232:52 pm -
2 stops14h 03m
Tue 12/89:45 am -
1 stop17h 36m
Deal found 11/3![United Airlines logo]()
$679
This British Airways deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/810:55 am -
2 stops24h 00m
Tue 12/151:10 pm -
1 stop27h 19m
Deal found 11/1![British Airways logo]()
$683
This Finnair deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2312:54 pm -
1 stop15h 51m
Wed 12/26:40 pm -
2 stops33h 44m
Deal found 11/3![Finnair logo]()
$686
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:30 am -
1 stop16h 05m
Tue 11/241:30 pm -
1 stop15h 24m
Deal found 11/4![Delta logo]()
$686
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:30 am -
1 stop21h 15m
Tue 11/241:10 pm -
1 stop16h 13m
Deal found 11/4![American Airlines logo]()
$686
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/303:47 pm -
1 stop13h 33m
Fri 12/1810:00 am -
1 stop14h 30m
Deal found 11/5![Delta logo]()
$686
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/812:40 pm -
2 stops14h 55m
Tue 11/2410:00 am -
1 stop14h 08m
Deal found 10/31![Delta logo]()
$690
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:00 am -
2 stops18h 45m
Wed 12/1611:45 am -
2 stops18h 06m
Deal found 10/31![Delta logo]()
$690
This Air France deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:30 am -
2 stops15h 15m
Tue 11/241:30 pm -
1 stop15h 24m
Deal found 11/4![Multiple Airlines logo]()
$691
This FlightHub deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/85:34 pm -
2 stops16h 56m
Tue 12/151:05 pm -
2 stops33h 48m
Deal found 11/1![Multiple Airlines logo]()
$708
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:00 am -
2 stops18h 45m
Tue 11/246:10 am -
2 stops23h 43m
Deal found 11/4![Delta logo]()
$712
Best flights from South Carolina to ItalyDiscover carefully curated flight deals from South Carolina to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 5, 2026.
Discover carefully curated flight deals from South Carolina to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 5, 2026.
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2310:23 am -
2 stops15h 32m
Tue 12/811:00 am -
2 stops18h 59m
Deal found 11/3![United Airlines logo]()
$679
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/303:47 pm -
1 stop13h 33m
Fri 12/1810:00 am -
1 stop14h 30m
Deal found 11/3![Delta logo]()
$686
This United deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:00 am -
1 stop19h 30m
Mon 12/75:15 pm -
2 stops51h 13m
Deal found 11/2![Multiple Airlines logo]()
$747
This British Airways deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/1510:55 am -
2 stops29h 00m
Mon 3/19:00 pm -
2 stops29h 40m
Deal found 11/4![British Airways logo]()
$755
This KLM deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/151:00 pm -
1 stop16h 20m
Mon 3/11:30 pm -
1 stop16h 28m
Deal found 11/2![KLM logo]()
$778
This Finnair deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/232:09 pm -
2 stops22h 06m
Mon 11/307:00 pm -
2 stops33h 03m
Deal found 11/4![Finnair logo]()
$817
This Scandinavian Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Scandinavian Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/16:00 am -
2 stops22h 55m
Sat 4/109:20 am -
2 stops18h 26m
Deal found 11/3![Scandinavian Airlines logo]()
$827
This KAYAK deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2311:58 am -
1 stop13h 32m
Mon 11/305:15 pm -
2 stops36h 25m
Deal found 11/5![Lufthansa logo]()
$861
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1612:03 pm -
3 stops18h 07m
Fri 3/2612:45 pm -
2 stops27h 19m
Deal found 10/31![American Airlines logo]()
$1,270
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/25:35 am -
2 stops20h 10m
Wed 12/161:30 pm -
1 stop16h 21m
Deal found 10/31![Delta logo]()
$690
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/32:57 pm -
1 stop11h 33m
Thu 12/1011:15 am -
2 stops40h 06m
Deal found 11/5![United Airlines logo]()
$716
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/207:50 pm -
1 stop30h 40m
Sun 2/281:15 pm -
2 stops34h 07m
Deal found 11/3![United Airlines logo]()
$722
This Air France deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/2112:38 pm -
1 stop16h 07m
Sat 2/2710:25 am -
1 stop16h 41m
Deal found 10/31![Multiple Airlines logo]()
$814
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/222:50 pm -
1 stop14h 30m
Mon 3/2210:10 am -
2 stops28h 58m
Deal found 11/1![Delta logo]()
$777
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/42:57 pm -
1 stop11h 33m
Tue 12/810:30 am -
1 stop19h 29m
Deal found 11/4![United Airlines logo]()
$731
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2312:58 pm -
1 stop13h 17m
Wed 12/210:25 am -
1 stop14h 57m
Deal found 11/3![Delta logo]()
$785
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:56 pm -
2 stops29h 34m
Thu 12/109:45 am -
1 stop20h 14m
Deal found 10/31![United Airlines logo]()
$732
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/43:03 pm -
1 stop11h 27m
Tue 12/811:15 am -
2 stops42h 25m
Deal found 11/3![United Airlines logo]()
$741
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1411:53 am -
2 stops15h 42m
Mon 12/2110:00 am -
2 stops30h 10m
Deal found 11/1![Delta logo]()
$839
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/289:55 am -
2 stops16h 00m
Tue 3/911:15 am -
2 stops40h 45m
Deal found 11/2![United Airlines logo]()
$742
This FlightHub deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:00 pm -
2 stops15h 20m
Mon 11/303:05 pm -
2 stops34h 10m
Deal found 11/1![Multiple Airlines logo]()
$1,087
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/127:30 am -
2 stops17h 15m
Wed 4/219:00 am -
2 stops19h 55m
Deal found 11/5![Delta logo]()
$854
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/216:05 am -
1 stop19h 50m
Sat 2/272:10 pm -
2 stops34h 59m
Deal found 10/31![United Airlines logo]()
$745
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/287:59 pm -
1 stop31h 26m
Fri 4/29:00 am -
1 stop18h 05m
Deal found 11/4![Delta logo]()
$855
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/86:30 am -
2 stops22h 10m
Tue 12/159:45 am -
1 stop19h 55m
Deal found 11/1![United Airlines logo]()
$746
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/2810:10 am -
1 stop18h 40m
Fri 4/212:45 pm -
2 stops17h 09m
Deal found 11/4![Delta logo]()
$855
This Air Canada deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/238:45 am -
3 stops18h 55m
Fri 4/306:40 am -
3 stops22h 39m
Deal found 11/2![Air Canada logo]()
$3,181
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/305:12 pm -
2 stops33h 18m
Fri 12/189:45 am -
2 stops18h 50m
Deal found 11/4![United Airlines logo]()
$746
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/512:38 pm -
2 stops19h 47m
Sun 3/146:40 am -
2 stops19h 02m
Deal found 11/4![Delta logo]()
$855
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/316:29 pm -
2 stops32h 01m
Thu 2/411:15 am -
2 stops36h 33m
Deal found 11/2![United Airlines logo]()
$753
Last-minute flights from South Carolina to ItalyDiscover last-minute flight deals from South Carolina to Italy. Data last updated November 5, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Italy. Data last updated November 5, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/811:15 am -
2 stops16h 20m
Tue 11/2410:00 am -
2 stops17h 13m
Deal found 10/31![Delta logo]()
$690
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:30 am -
1 stop21h 15m
Tue 11/241:10 pm -
1 stop16h 13m
Deal found 11/4![American Airlines logo]()
$686
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:00 am -
2 stops18h 45m
Tue 11/246:10 am -
2 stops23h 43m
Deal found 11/4![Delta logo]()
$712
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:30 am -
1 stop16h 05m
Tue 11/241:30 pm -
1 stop15h 24m
Deal found 11/4![Delta logo]()
$686
This Air France deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:30 am -
2 stops15h 15m
Tue 11/241:30 pm -
1 stop15h 24m
Deal found 11/4![Multiple Airlines logo]()
$691
This Booking.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2312:54 pm -
1 stop15h 51m
Tue 12/81:10 pm -
1 stop16h 16m
Deal found 11/3![British Airways logo]()
$677
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/232:52 pm -
2 stops14h 03m
Tue 12/89:45 am -
1 stop17h 36m
Deal found 11/3![United Airlines logo]()
$679
This Finnair deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2312:54 pm -
1 stop15h 51m
Wed 12/26:40 pm -
2 stops33h 44m
Deal found 11/3![Finnair logo]()
$686
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/303:47 pm -
1 stop13h 33m
Fri 12/1810:00 am -
1 stop14h 30m
Deal found 11/5![Delta logo]()
$686
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/25:35 am -
2 stops20h 10m
Wed 12/161:30 pm -
1 stop16h 21m
Deal found 10/31![Delta logo]()
$690
This British Airways deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/810:55 am -
2 stops24h 00m
Tue 12/151:10 pm -
1 stop27h 19m
Deal found 11/1![British Airways logo]()
$683
This FlightHub deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/85:34 pm -
2 stops16h 56m
Tue 12/151:05 pm -
2 stops33h 48m
Deal found 11/1![Multiple Airlines logo]()
$708
One-way flights from South Carolina to ItalySearch for one-way flight options from South Carolina to Italy. Find affordable one-way fares based on user searches. Data last updated November 5, 2026.
Search for one-way flight options from South Carolina to Italy. Find affordable one-way fares based on user searches. Data last updated November 5, 2026.
This oojo deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2210:15 am -
1 stop17h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![Lufthansa logo]()
$330
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2212:52 pm -
2 stops15h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Delta logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/123:07 pm -
2 stops49h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Multiple Airlines logo]()
$351
This deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/112:54 pm -
1 stop11h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![United Airlines logo]()
$437
This Cheapflightsfares deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/308:30 am -
2 stops20h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Aer Lingus logo]()
$439
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/282:13 pm -
3 stops24h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![Multiple Airlines logo]()
$485
This oojo deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/303:02 pm -
1 stop11h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Lufthansa logo]()
$522
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/242:13 pm -
3 stops44h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Multiple Airlines logo]()
$539
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/267:59 pm -
1 stop30h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Delta logo]()
$543
This Air Canada deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/254:55 pm -
2 stops58h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Air Canada logo]()
$546
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/233:42 pm -
3 stops50h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Multiple Airlines logo]()
$550
This oojo deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:27 am -
1 stop14h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Lufthansa logo]()
$557
Find flight deals from South Carolina to Italy
Keep the following information in mind while searching for South Carolina to Italy flight deals. Data was last updated November 5, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $677 (Booking.com) |
One-way from | $330 (oojo) |
Popular in | July |
Cheapest in | January |
Average price | $1,255 |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 5, 2026.
Use the filters below to find and compare flights from South Carolina to Italy that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonRome
CHS Charleston - FCO Rome Fiumicino
CHSFCO
Charleston
Mon 3/22
10:15 am-8:30 am
1 stop17h 15m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$330
CharlestonRome
CHS Charleston - FCO Rome Fiumicino
CHSFCO
Charleston
Mon 3/22
12:52 pm-9:20 am
2 stops15h 28m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$349
CharlestonFlorence
CHS Charleston - FLR Florence Peretola
CHSFLR
Charleston
Tue 1/12
3:07 pm-11:05 pm
2 stops49h 58m
Florence Peretola
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$351
Quickest round-trip
GreenvilleRome
GSP Greenville - FCO Rome Fiumicino
GSPFCO
Greenville
Sun 4/11
2:54 pm-8:15 am
1 stop11h 21m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$437
CharlestonMilan
CHS Charleston - MXP Milan Malpensa
CHSMXP
Charleston
Thu 1/28
2:13 pm-8:55 pm
3 stops24h 42m
Milan Malpensa
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$485
Myrtle BeachRome
MYR Myrtle Beach Intl - FCO Rome Fiumicino
MYRFCO
Myrtle Beach Intl
Wed 11/18
11:27 am-7:55 am
1 stop14h 28m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$557
Myrtle BeachRome
MYR Myrtle Beach Intl - FCO Rome Fiumicino
MYRFCO
Myrtle Beach Intl
Wed 11/18
1:29 pm-4:55 pm
2 stops21h 26m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$569
CharlestonMilan
CHS Charleston - MXP Milan Malpensa
CHSMXP
Charleston
Thu 1/28
10:14 am-7:30 am
1 stop15h 16m
Milan Malpensa
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$571
Myrtle BeachRome
MYR Myrtle Beach Intl - FCO Rome Fiumicino
MYRFCO
Myrtle Beach Intl
Wed 11/18
11:27 am-10:55 am
1 stop17h 28m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$574
Myrtle BeachRome
MYR Myrtle Beach Intl - FCO Rome Fiumicino
MYRFCO
Myrtle Beach Intl
Tue 12/15
4:08 pm-7:55 pm
3 stops45h 47m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$574
Showing 1-10 of 54 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Italy
Have a flexible travel schedule? Discover the best time to fly to Italy from South Carolina with our price prediction graph.
CHS-FCO
GSP-FCO
MYR-FCO
CAE-FCO
GSP-MXP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Italy
USSC-IT0
CHS-FCO
GSP-FCO
MYR-FCO
CAE-FCO
What is the cheapest month to book a flight from South Carolina to Italy?
Currently, February is the cheapest month in which you can book a flight from South Carolina to Italy (average of $555). Flying from South Carolina to Italy in June is currently the most expensive (average of $1,558). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from South Carolina to Italy?
The price you pay for your flight from South Carolina to Italy may vary depending on when you book. For the best chance of a lower fare, look to book 47 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for South Carolina to Italy
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Italy by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Italy by cabin class
Find flights from South Carolina to Italy, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Carolina and Italy flights
Browse other South Carolina and Italy flight options. Last updated on November 5, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Italy
Find the right flight back to South Carolina after your stay in Italy
South Carolina to Italy flights
Consider these flights traveling from South Carolina to Italy.
Fly to Italy regions
Consider these flights traveling to Italy regions.
Top 5 airlines flying from South Carolina to Italy
Discover the top 5 airlines that operate flights from South Carolina to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$497 | Average$1,353 | FlexibilityNo cancel fee | On-time76% | |
| Cheapest$503 | Average$1,268 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$609 | Average$1,175 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$616 | Average$1,203 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$759 | Average$1,306 | FlexibilityNo cancel fee | On-time71% |