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Italy

$307+ Cheap flights from South Carolina to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/28. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — NAP
Apr 29 — May 61
Wed 4/29
Wed 5/6
1 adult, Economy
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Cheap flight deals from South Carolina to Italy

Cheapest flights from South Carolina to Italy
Explore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 30, 2026.

This Cheapflightsfares deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:40 pm
CLT
-
VCE
1 stop12h 05m
Lufthansa
Wed 8/196:30 am
VCE
-
CLT
1 stop16h 15m
Lufthansa
Deal found 3/27$674
This Cheapflightsfares deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:50 pm
CLT
-
VCE
1 stop11h 55m
Lufthansa
Tue 12/86:45 am
VCE
-
CLT
2 stops22h 49m
Lufthansa
Deal found 3/26$682
This Cheapflightsfares deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:50 pm
CLT
-
FLR
1 stop15h 40m
Lufthansa
Fri 12/118:00 am
FLR
-
CLT
1 stop14h 55m
Lufthansa
Deal found 3/25$683
This Cheapflightsfares deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/176:40 pm
CLT
-
MXP
1 stop16h 00m
Lufthansa
Tue 8/256:20 am
MXP
-
CLT
1 stop16h 25m
Lufthansa
Deal found 3/26$686
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:40 pm
CLT
-
MXP
1 stop11h 35m
Lufthansa
Tue 5/126:20 am
MXP
-
CLT
1 stop16h 25m
Lufthansa
Deal found 3/25$687
This Cheapflightsfares deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:40 pm
CLT
-
MXP
1 stop16h 00m
Lufthansa
Wed 5/136:20 am
MXP
-
CLT
1 stop16h 25m
Lufthansa
Deal found 3/25$690
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:40 pm
CLT
-
LIN
1 stop12h 20m
Lufthansa
Tue 5/129:50 am
LIN
-
CLT
1 stop12h 55m
Lufthansa
Deal found 3/25$691
This Air Canada deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1010:27 am
CLT
-
VCE
2 stops40h 43m
Air Canada
Thu 8/2012:20 pm
VCE
-
CLT
2 stops42h 44m
Air Canada
Deal found 3/27$696
This United Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/157:49 pm
CLT
-
VCE
1 stop30h 06m
United Airlines
Fri 8/2112:20 pm
VCE
-
CLT
1 stop32h 42m
United Airlines
Deal found 3/26$699
This British Airways deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/161:04 pm
CLT
-
FLR
2 stops16h 46m
Multiple Airlines
Thu 8/277:05 am
FLR
-
CLT
2 stops18h 03m
Multiple Airlines
Deal found 3/25$701
This Cheapflightsfares deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:05 am
CLT
-
VCE
2 stops23h 55m
SWISS
Wed 8/197:40 pm
VCE
-
CLT
2 stops27h 05m
SWISS
Deal found 3/29$701
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:40 pm
CLT
-
VCE
1 stop12h 05m
Lufthansa
Wed 8/196:30 am
VCE
-
CLT
1 stop16h 15m
Lufthansa
Deal found 3/27$705

Find flight deals from South Carolina to Italy

Keep the following information in mind while searching for South Carolina to Italy flight deals. Data was last updated March 30, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$674
(Cheapflightsfares)

One-way from

$307
(Kiwi.com)

Popular in

June

Cheapest in

January

Average price

$916
Provider with most accurate pricing for Myrtle Beach Intl-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Rome (ROM) flights.
Search Deals
From South Carolina to Italy
Search Deals
One-way flight from South Carolina to Italy
Search Deals
Highest demand for flights based on searches. 29% potential increase in price ($464 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 10% potential price decrease ($102 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 30, 2026.
Use the filters below to find and compare flights from South Carolina to Italy that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteMilan

CLT - MXP

CLTMXP

Charlotte Douglas

Wed 4/15

6:40 pm-4:40 pm

1 stop16h 00m

Milan Malpensa

Wed 4/22

12:20 pm-8:57 pm

2 stops38h 37m

$710

CharlestonMilan

CHS - MXP

CHSMXP

Charleston

Thu 8/13

8:55 am-1:20 pm

1 stop22h 25m

Milan Malpensa

Sat 8/22

9:00 am-9:48 pm

2 stops18h 48m

$714

CharlestonMilan

CHS - LIN

CHSLIN

Charleston

Thu 8/13

2:25 pm-11:20 am

2 stops14h 55m

Milan Linate

Sat 8/22

6:40 am-8:46 pm

2 stops20h 06m

$723

CharlotteFlorence

CLT - FLR

CLTFLR

Charlotte Douglas

Sun 8/16

1:04 pm-11:50 am

2 stops16h 46m

Florence Peretola

Thu 8/27

12:25 pm-11:59 pm

2 stops17h 34m

$726

CharlotteFlorence

CLT - FLR

CLTFLR

Charlotte Douglas

Tue 8/11

1:04 pm-11:35 am

2 stops16h 31m

Florence Peretola

Fri 8/21

7:05 am-7:08 pm

2 stops18h 03m

$726

CharlestonMilan

CHS - MXP

CHSMXP

Charleston

Thu 8/13

2:25 pm-10:25 am

2 stops14h 00m

Milan Malpensa

Sat 8/22

6:45 am-11:57 pm

2 stops23h 12m

$727

CharlotteFlorence

CLT - FLR

CLTFLR

Charlotte Douglas

Tue 8/11

10:23 am-4:35 pm

2 stops24h 12m

Florence Peretola

Fri 8/21

8:15 am-11:58 pm

2 stops21h 43m

$742

CharlotteMilan

CLT - LIN

CLTLIN

Charlotte Douglas

Wed 4/15

2:04 pm-1:40 pm

2 stops17h 36m

Milan Linate

Wed 4/22

10:25 am-9:37 pm

2 stops17h 12m

$745

CharlestonMilan

CHS - MXP

CHSMXP

Charleston

Thu 4/23

6:30 am-7:30 am

1 stop19h 00m

Milan Malpensa

Wed 5/6

9:45 am-6:59 pm

2 stops15h 14m

$762

CharlestonMilan

CHS - MXP

CHSMXP

Charleston

Thu 8/13

10:59 am-10:05 am

1 stop17h 06m

Milan Malpensa

Sat 8/22

2:20 pm-7:32 pm

1 stop35h 12m

$763

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/25

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from South Carolina to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Italy

What is the cheapest month to book a flight from South Carolina to Italy?

Currently, October is the cheapest month in which you can book a flight from South Carolina to Italy (average of $192). Flying from South Carolina to Italy in July is currently the most expensive (average of $772). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to IT?

Find hourly flight availability from South Carolina to Italy. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 30, 2026.

One of the essential ways to save on airfare from South Carolina to Italy is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 33% on airfare.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Italy?

    For as low as $723, United Airlines can have you in Italy from South Carolina in 14h 55m. The distance from South Carolina to Italy is about 4612 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from South Carolina to Italy one-way?

    $298 is the cheapest one-way deal found within the past few days, from Neos Air. You may also be able to find cheap deals on Air France and Iberia, with prices starting from $454 and $483, respectively.

  • Can I find deals for flights from South Carolina to Italy that include hotel bookings?

    Yes. In addition to deals on South Carolina to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Italy.

  • Can I find deals for business class flights from South Carolina to Italy?

    Yes. Cheapflights offers flight deals from South Carolina to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Italy?

    Currently, October is the cheapest month in which you can book a flight from South Carolina to Italy (average of $192). Flying from South Carolina to Italy in July is currently the most expensive (average of $772). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Italy

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from South Carolina to Italy

Discover the top 6 airlines that operate flights from South Carolina to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 30, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$307Average$1,113FlexibilityNo cancel feeOn-time69%
British AirwaysCheapest$468Average$894FlexibilityNo cancel feeOn-time70%
DeltaCheapest$503Average$1,104FlexibilityNo cancel feeOn-timeN/A
KLMCheapest$507Average$1,012FlexibilityNo cancel feeOn-time75%
American AirlinesCheapest$699Average$1,145FlexibilityNo cancel feeOn-time71%
LufthansaCheapest$745Average$1,379FlexibilityNo cancel feeOn-time76%

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