$248+ Cheap flights from South Carolina to Italy
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/28. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — NAP
Aug 1 — Aug 81
Round-trip
1 adult, Economy
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Cheapest flights from South Carolina to ItalyExplore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2026.
Explore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2026.
This oojo deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:50 pm
CLT
- VCE
1 stop11h 30m
Lufthansa
Tue 12/88:00 am
VCE
- CLT
1 stop14h 55m
Lufthansa
Deal found 6/28![Lufthansa logo]()
$701
This Cheapflightsfares deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:50 pm
CLT
- VCE
2 stops17h 35m
SWISS
Tue 12/89:40 am
VCE
- CLT
2 stops17h 43m
SWISS
Deal found 6/28![SWISS logo]()
$703
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/912:20 pm
CLT
- MXP
1 stop13h 10m
United Airlines
Tue 11/1712:55 pm
MXP
- CLT
2 stops30h 55m
United Airlines
Deal found 6/30![United Airlines logo]()
$706
This Justfly.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:00 am
CLT
- MXP
2 stops22h 05m
Air Canada
Tue 11/1712:55 pm
MXP
- CLT
2 stops34h 02m
Air Canada
Deal found 6/30![Air Canada logo]()
$709
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/98:15 pm
CLT
- MXP
1 stop17h 35m
American Airlines
Wed 11/186:20 am
MXP
- CLT
1 stop14h 10m
American Airlines
Deal found 6/30![American Airlines logo]()
$715
This Cheapflightsfares deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:50 pm
CLT
- MXP
2 stops22h 00m
SWISS
Wed 11/186:45 am
MXP
- CLT
2 stops20h 48m
SWISS
Deal found 6/30![SWISS logo]()
$716
This FlightHub deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:50 pm
CLT
- MXP
1 stop11h 45m
Lufthansa
Thu 11/196:05 am
MXP
- CLT
1 stop16h 50m
Lufthansa
Deal found 6/30![Lufthansa logo]()
$722
This Cheapflightsfares deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:50 pm
CLT
- MXP
1 stop11h 45m
Lufthansa
Wed 11/186:55 am
MXP
- CLT
2 stops22h 44m
Lufthansa
Deal found 6/30![Lufthansa logo]()
$723
This Cheapflightsfares deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:50 pm
CLT
- MXP
2 stops17h 40m
SWISS
Thu 12/36:45 am
MXP
- CLT
2 stops16h 10m
SWISS
Deal found 7/1![SWISS logo]()
$724
This British Airways deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/31:01 pm
CLT
- FLR
2 stops16h 29m
Multiple Airlines
Wed 8/197:05 am
FLR
- CLT
2 stops16h 37m
Multiple Airlines
Deal found 6/30![Multiple Airlines logo]()
$725
This United deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/18:05 am
CLT
- MXP
2 stops17h 25m
Multiple Airlines
Thu 12/39:50 am
MXP
- CLT
1 stop13h 05m
Multiple Airlines
Deal found 7/1![Multiple Airlines logo]()
$725
This Lufthansa deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:50 pm
CLT
- LIN
1 stop18h 00m
Lufthansa
Thu 11/199:45 am
LIN
- CLT
1 stop13h 10m
Lufthansa
Deal found 6/30![Lufthansa logo]()
$726
Best flights from South Carolina to ItalyDiscover carefully curated flight deals from South Carolina to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 2, 2026.
Discover carefully curated flight deals from South Carolina to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 2, 2026.
This Lufthansa deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/176:40 pm
CLT
- MXP
1 stop16h 00m
Lufthansa
Tue 8/258:45 am
MXP
- CLT
1 stop14h 00m
Lufthansa
Deal found 6/28![Lufthansa logo]()
$760
This British Airways deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/111:02 pm
CLT
- FLR
2 stops16h 33m
Multiple Airlines
Fri 8/217:05 am
FLR
- CLT
2 stops18h 08m
Multiple Airlines
Deal found 7/1![Multiple Airlines logo]()
$774
This SWISS deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SWISS is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/168:05 am
CLT
- MXP
2 stops19h 45m
SWISS
Tue 8/2510:40 am
MXP
- CLT
2 stops17h 01m
SWISS
Deal found 6/28![SWISS logo]()
$777
This United Airlines deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1510:19 am
CHS
- FCO
1 stop16h 11m
United Airlines
Thu 11/1910:30 am
FCO
- CHS
1 stop19h 18m
United Airlines
Deal found 6/27![United Airlines logo]()
$790
This KLM deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/127:10 pm
CHS
- FCO
1 stop30h 25m
KLM
Wed 10/219:45 am
FCO
- CHS
1 stop20h 11m
KLM
Deal found 6/28![KLM logo]()
$797
This Air France deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/12:30 pm
CHS
- MXP
1 stop13h 20m
Air France
Thu 12/101:05 pm
MXP
- CHS
1 stop16h 51m
Air France
Deal found 6/27![Air France logo]()
$830
This Delta deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/182:28 pm
CLT
- FCO
1 stop11h 27m
Delta
Sun 11/81:30 pm
FCO
- CLT
1 stop14h 23m
Delta
Deal found 6/28![Delta logo]()
$832
This American Airlines deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/19:02 am
CHS
- MXP
2 stops17h 03m
American Airlines
Thu 12/1010:20 am
MXP
- CHS
2 stops14h 50m
American Airlines
Deal found 6/27![American Airlines logo]()
$835
This Scandinavian Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Scandinavian Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/205:02 pm
CLT
- MXP
2 stops20h 08m
Scandinavian Airlines
Thu 9/2411:25 am
MXP
- CLT
2 stops17h 19m
Scandinavian Airlines
Deal found 6/29![Scandinavian Airlines logo]()
$887
This Finnair deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:29 pm
CLT
- FCO
2 stops17h 26m
Finnair
Tue 12/810:40 am
FCO
- CLT
2 stops27h 55m
Finnair
Deal found 7/1![Finnair logo]()
$1,089
This British Airways deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/217:15 pm
CLT
- FCO
Nonstop9h 05m
British Airways
Fri 8/281:30 pm
FCO
- CLT
Nonstop10h 45m
British Airways
Deal found 6/27![British Airways logo]()
$1,119
This Air Canada deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/12:30 pm
CHS
- LIN
3 stops17h 35m
Air Canada
Thu 12/106:25 am
LIN
- CHS
3 stops22h 54m
Air Canada
Deal found 6/27![Air Canada logo]()
$1,428
This Lufthansa deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:40 pm
CLT
- LIN
1 stop12h 20m
Lufthansa
Tue 8/2510:35 am
LIN
- CLT
2 stops14h 21m
Lufthansa
Deal found 6/28![Lufthansa logo]()
$772
This British Airways deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/181:02 pm
CLT
- FLR
2 stops16h 33m
Multiple Airlines
Tue 8/257:05 am
FLR
- CLT
2 stops17h 31m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$774
This United Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/96:00 am
CLT
- NAP
2 stops23h 40m
United Airlines
Tue 8/252:00 pm
NAP
- CLT
2 stops15h 56m
United Airlines
Deal found 7/2![United Airlines logo]()
$810
This Delta deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:25 pm
CHS
- LIN
2 stops14h 30m
Delta
Thu 12/106:30 am
LIN
- CHS
2 stops18h 24m
Delta
Deal found 6/27![Delta logo]()
$841
This United deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/151:00 pm
CLT
- FLR
2 stops21h 30m
Multiple Airlines
Wed 11/256:30 am
FLR
- CLT
2 stops20h 36m
Multiple Airlines
Deal found 6/27![Multiple Airlines logo]()
$780
This United Airlines deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:00 am
CLT
- LIN
2 stops24h 20m
United Airlines
Mon 8/246:50 am
LIN
- CLT
2 stops39h 55m
United Airlines
Deal found 6/28![United Airlines logo]()
$811
This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/151:17 pm
CLT
- LIN
2 stops16h 03m
Delta
Sat 8/2211:00 am
LIN
- CLT
2 stops17h 07m
Delta
Deal found 7/1![Delta logo]()
$875
This Lufthansa deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/276:40 pm
CLT
- LIN
1 stop17h 05m
Lufthansa
Mon 8/36:25 pm
LIN
- CLT
1 stop28h 20m
Lufthansa
Deal found 6/29![Lufthansa logo]()
$882
This United Airlines deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/173:00 pm
CLT
- LIN
2 stops15h 20m
United Airlines
Mon 8/246:50 am
LIN
- CLT
2 stops39h 55m
United Airlines
Deal found 6/28![United Airlines logo]()
$811
This Mytrip deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/93:40 pm
CLT
- CIA
2 stops23h 45m
Multiple Airlines
Tue 8/256:05 am
CIA
- CLT
2 stops16h 40m
Multiple Airlines
Deal found 6/30![Multiple Airlines logo]()
$882
This Cheapflightsfares deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:40 pm
CLT
- NAP
2 stops18h 00m
SWISS
Thu 7/239:30 am
NAP
- CLT
2 stops17h 59m
SWISS
Deal found 6/27![SWISS logo]()
$1,068
This Delta deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/47:45 pm
CLT
- VCE
2 stops18h 30m
Delta
Tue 8/1111:45 am
VCE
- CLT
2 stops16h 35m
Delta
Deal found 6/27![Delta logo]()
$885
This United Airlines deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/157:00 am
CLT
- MXP
1 stop18h 30m
United Airlines
Wed 8/269:45 am
MXP
- CLT
1 stop13h 10m
United Airlines
Deal found 6/28![United Airlines logo]()
$814
This Lufthansa deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:40 pm
CLT
- LIN
1 stop12h 20m
Lufthansa
Sun 9/209:50 am
LIN
- CLT
1 stop12h 55m
Lufthansa
Deal found 6/29![Lufthansa logo]()
$906
This Mytrip deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/113:40 pm
CLT
- CIA
2 stops19h 00m
Multiple Airlines
Tue 8/186:05 am
CIA
- CLT
2 stops16h 40m
Multiple Airlines
Deal found 6/29![Multiple Airlines logo]()
$894
This United Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:27 pm
CHS
- FCO
1 stop11h 28m
United Airlines
Sun 11/81:15 pm
FCO
- CHS
2 stops31h 19m
United Airlines
Deal found 7/2![United Airlines logo]()
$854
This Lufthansa deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:40 pm
CLT
- LIN
1 stop12h 20m
Lufthansa
Fri 9/259:50 am
LIN
- CLT
1 stop12h 55m
Lufthansa
Deal found 7/1![Lufthansa logo]()
$940
This Delta deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:21 pm
CLT
- LIN
2 stops15h 44m
Delta
Fri 10/26:40 am
LIN
- CLT
2 stops18h 00m
Delta
Deal found 6/28![Delta logo]()
$951
Last-minute flights from South Carolina to ItalyDiscover last-minute flight deals from South Carolina to Italy. Data last updated July 2, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Italy. Data last updated July 2, 2026 and is based on user searches.
This British Airways deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/31:01 pm
CLT
- FLR
2 stops16h 29m
Multiple Airlines
Wed 8/197:05 am
FLR
- CLT
2 stops16h 37m
Multiple Airlines
Deal found 6/30![Multiple Airlines logo]()
$725
This Trip.com deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/39:15 am
CLT
- MXP
2 stops19h 05m
Air Canada
Wed 8/1912:20 pm
MXP
- CLT
2 stops32h 39m
Air Canada
Deal found 6/27![Air Canada logo]()
$735
This lol.travel deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/311:45 am
CLT
- MXP
1 stop15h 20m
Finnair
Wed 8/1911:00 am
MXP
- CLT
1 stop14h 19m
Finnair
Deal found 6/27![Finnair logo]()
$737
This Trip.com deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/36:40 pm
CLT
- VCE
1 stop15h 55m
Multiple Airlines
Wed 8/1912:20 pm
VCE
- CLT
1 stop32h 39m
Multiple Airlines
Deal found 6/29![Multiple Airlines logo]()
$743
This Kiwi.com deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:40 pm
CLT
- MXP
1 stop11h 35m
Multiple Airlines
Tue 8/2510:40 am
MXP
- CLT
2 stops17h 01m
Multiple Airlines
Deal found 7/1![Multiple Airlines logo]()
$731
This Kiwi.com deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:40 pm
CLT
- LIN
1 stop12h 20m
Lufthansa
Tue 8/251:40 pm
LIN
- CLT
2 stops16h 16m
Lufthansa
Deal found 7/1![Lufthansa logo]()
$745
This United Airlines deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/1612:34 pm
CLT
- MXP
1 stop18h 46m
United Airlines
Tue 8/2512:20 pm
MXP
- CLT
2 stops29h 05m
United Airlines
Deal found 6/28![United Airlines logo]()
$744
This Cheapflightsfares deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/178:05 am
CLT
- MXP
2 stops19h 45m
SWISS
Wed 8/265:50 am
MXP
- CLT
2 stops21h 51m
SWISS
Deal found 6/28![SWISS logo]()
$738
This Justfly.com deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/176:40 pm
CLT
- MXP
1 stop16h 00m
Multiple Airlines
Wed 8/2612:20 pm
MXP
- CLT
1 stop32h 39m
Multiple Airlines
Deal found 6/28![Multiple Airlines logo]()
$739
This United Airlines deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/176:40 pm
CLT
- MXP
1 stop16h 00m
United Airlines
Fri 8/2812:20 pm
MXP
- CLT
2 stops34h 14m
United Airlines
Deal found 6/28![United Airlines logo]()
$747
This Cheapflightsfares deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/178:05 am
CLT
- VCE
2 stops18h 30m
SWISS
Fri 8/2810:20 am
VCE
- CLT
2 stops17h 21m
SWISS
Deal found 6/30![SWISS logo]()
$747
This eDestinos deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2512:00 pm
CLT
- MXP
1 stop15h 05m
Iberia
Tue 9/811:00 am
MXP
- CLT
1 stop12h 42m
Iberia
Deal found 7/1![Iberia logo]()
$742
One-way flights from South Carolina to ItalySearch for one-way flight options from South Carolina to Italy. Find affordable one-way fares based on user searches. Data last updated July 2, 2026.
Search for one-way flight options from South Carolina to Italy. Find affordable one-way fares based on user searches. Data last updated July 2, 2026.
This BusinessClass deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2812:59 pm
CLT
- LIN
2 stops15h 41m
Aer Lingus
Deal found 6/30![Aer Lingus logo]()
$248
This KAYAK deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/211:02 pm
CLT
- LIN
2 stops15h 38m
Aer Lingus
Deal found 7/1![Aer Lingus logo]()
$279
This KAYAK deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/201:01 pm
CLT
- LIN
2 stops15h 39m
Aer Lingus
Deal found 6/28![Aer Lingus logo]()
$292
This Ovago deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/261:01 pm
CLT
- LIN
2 stops15h 39m
Aer Lingus
Deal found 7/1![Aer Lingus logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/105:43 pm
CLT
- FCO
1 stop14h 47m
Multiple Airlines
Deal found 6/30![Multiple Airlines logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/155:43 pm
CLT
- FCO
1 stop14h 47m
Multiple Airlines
Deal found 6/30![Multiple Airlines logo]()
$304
This Kiwi.com deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/258:02 pm
CLT
- VCE
2 stops46h 43m
Multiple Airlines
Deal found 6/29![Multiple Airlines logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:33 pm
CLT
- FCO
1 stop14h 57m
Multiple Airlines
Deal found 6/28![Multiple Airlines logo]()
$310
This Kiwi.com deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2812:24 pm
CLT
- FCO
3 stops37h 36m
Multiple Airlines
Deal found 7/1![Multiple Airlines logo]()
$316
This Kiwi.com deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/18:02 pm
CLT
- MXP
2 stops56h 43m
Multiple Airlines
Deal found 6/28![Multiple Airlines logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/123:00 pm
CLT
- FCO
2 stops20h 10m
Brussels Airlines
Deal found 6/30![Brussels Airlines logo]()
$321
This Kiwi.com deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/141:48 pm
CLT
- MXP
2 stops22h 12m
Multiple Airlines
Deal found 6/29![Multiple Airlines logo]()
$321
Find flight deals from South Carolina to Italy
Keep the following information in mind while searching for South Carolina to Italy flight deals. Data was last updated July 2, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $701 (oojo) |
One-way from | $248 (BusinessClass) |
Popular in | July |
Cheapest in | January |
Average price | $2,686 |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 2, 2026.
Use the filters below to find and compare flights from South Carolina to Italy that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlotteMilan
CLT - MXP
CLTMXP
Charlotte Douglas
Mon 8/17
6:40 pm-4:40 pm
1 stop16h 00m
Milan Malpensa
Tue 8/25
8:45 am-4:45 pm
1 stop14h 00m
$760
CharlotteMilan
CLT - LIN
CLTLIN
Charlotte Douglas
Sun 8/16
6:40 pm-1:00 pm
1 stop12h 20m
Milan Linate
Tue 8/25
10:35 am-6:56 pm
2 stops14h 21m
$772
CharlotteFlorence
CLT - FLR
CLTFLR
Charlotte Douglas
Tue 8/11
1:02 pm-11:35 am
2 stops16h 33m
Florence Peretola
Fri 8/21
7:05 am-7:13 pm
2 stops18h 08m
$774
CharlotteFlorence
CLT - FLR
CLTFLR
Charlotte Douglas
Tue 8/18
1:02 pm-11:35 am
2 stops16h 33m
Florence Peretola
Tue 8/25
7:05 am-6:36 pm
2 stops17h 31m
$774
CharlotteMilan
CLT - MXP
CLTMXP
Charlotte Douglas
Sun 8/16
8:05 am-9:50 am
2 stops19h 45m
Milan Malpensa
Tue 8/25
10:40 am-9:41 pm
2 stops17h 01m
$777
CharlotteFlorence
CLT - FLR
CLTFLR
Charlotte Douglas
Sun 11/15
1:00 pm-4:30 pm
2 stops21h 30m
Florence Peretola
Wed 11/25
6:30 am-9:06 pm
2 stops20h 36m
$780
CharlestonRome
CHS - FCO
CHSFCO
Charleston
Sun 11/15
10:19 am-8:30 am
1 stop16h 11m
Rome Fiumicino
Thu 11/19
10:30 am-11:48 pm
1 stop19h 18m
$790
CharlestonRome
CHS - FCO
CHSFCO
Charleston
Mon 10/12
7:10 pm-7:35 am
1 stop30h 25m
Rome Fiumicino
Wed 10/21
9:45 am-11:56 pm
1 stop20h 11m
$797
CharlotteNaples
CLT - NAP
CLTNAP
Charlotte Douglas
Sun 8/9
6:00 am-11:40 am
2 stops23h 40m
Naples
Tue 8/25
2:00 pm-11:56 pm
2 stops15h 56m
$810
CharlotteMilan
CLT - LIN
CLTLIN
Charlotte Douglas
Sun 8/16
6:00 am-12:20 pm
2 stops24h 20m
Milan Linate
Mon 8/24
6:50 am-4:45 pm
2 stops39h 55m
$811
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Italy
Have a flexible travel schedule? Discover the best time to fly to Italy from South Carolina with our price prediction graph.
CLT-LIN
CLT-FCO
CLT-VCE
CLT-MXP
CLT-FLR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Italy
USSC-IT0
CLT-LIN
CLT-FCO
CLT-VCE
CLT-MXP
What is the cheapest month to book a flight from South Carolina to Italy?
Currently, September is the cheapest month in which you can book a flight from South Carolina to Italy (average of $147). Flying from South Carolina to Italy in July is currently the most expensive (average of $715). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from South Carolina to Italy?
The price you pay for your flight from South Carolina to Italy may vary depending on when you book. For the best chance of a lower fare, look to book 42 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for South Carolina to Italy
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Italy by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Italy by cabin class
Find flights from South Carolina to Italy, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Carolina and Italy flights
Browse other South Carolina and Italy flight options. Last updated on July 2, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Italy
Find the right flight back to South Carolina after your stay in Italy
South Carolina to Italy flights
Consider these flights traveling from South Carolina to Italy.
Fly to Italy regions
Consider these flights traveling to Italy regions.
Top 6 airlines flying from South Carolina to Italy
Discover the top 6 airlines that operate flights from South Carolina to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$468 | Average$984 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$497 | Average$1,362 | FlexibilityNo cancel fee | On-time76% | |
| Cheapest$503 | Average$1,247 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$575 | Average$1,168 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$625 | Average$945 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$765 | Average$1,320 | FlexibilityNo cancel fee | On-time71% |