$330+ Cheap flights from South Carolina to Italy
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/22. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — FCO
Nov 26 — Dec 31
Round-trip
1 adult, Economy
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Find cheap flights from South Carolina to Italy with Cheapflights
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Cheapest flights from South Carolina to ItalyExplore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2026.
Explore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2026.
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/113:35 pm -
1 stop13h 20m
Wed 11/189:45 am -
1 stop18h 15m
Deal found 10/23![United Airlines logo]()
$676
This British Airways deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/910:54 am -
1 stop16h 06m
Wed 11/2511:00 am -
1 stop29h 33m
Deal found 10/22![British Airways logo]()
$676
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/212:53 pm -
1 stop14h 07m
Wed 12/161:10 pm -
2 stops16h 29m
Deal found 10/22![American Airlines logo]()
$681
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/910:54 am -
1 stop16h 06m
Wed 11/2511:00 am -
2 stops18h 31m
Deal found 10/22![American Airlines logo]()
$681
This Justfly.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:16 pm -
2 stops16h 39m
Wed 11/1811:00 am -
1 stop18h 18m
Deal found 10/23![British Airways logo]()
$683
This Expedia deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/92:33 pm -
2 stops18h 22m
Wed 12/161:10 pm -
1 stop35h 05m
Deal found 10/25![British Airways logo]()
$684
This British Airways deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/910:55 am -
2 stops22h 00m
Wed 12/161:10 pm -
1 stop27h 30m
Deal found 10/24![British Airways logo]()
$684
This Expedia deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2312:54 pm -
1 stop15h 51m
Wed 12/26:40 pm -
2 stops33h 44m
Deal found 10/25![Finnair logo]()
$686
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/118:12 am -
2 stops18h 48m
Wed 11/1811:00 am -
2 stops17h 51m
Deal found 10/23![American Airlines logo]()
$691
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/98:07 am -
2 stops18h 53m
Wed 12/161:10 pm -
2 stops15h 42m
Deal found 10/25![American Airlines logo]()
$691
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/178:17 am -
2 stops18h 43m
Wed 11/2511:00 am -
2 stops18h 06m
Deal found 10/27![American Airlines logo]()
$691
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/910:54 am -
2 stops16h 06m
Wed 12/161:10 pm -
2 stops15h 51m
Deal found 10/24![American Airlines logo]()
$691
Best flights from South Carolina to ItalyDiscover carefully curated flight deals from South Carolina to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 27, 2026.
Discover carefully curated flight deals from South Carolina to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 27, 2026.
This Travelocity deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2312:54 pm -
1 stop15h 51m
Wed 12/26:40 pm -
2 stops33h 44m
Deal found 10/22![Finnair logo]()
$676
This British Airways deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/910:54 am -
1 stop16h 06m
Wed 11/2511:00 am -
1 stop29h 33m
Deal found 10/22![British Airways logo]()
$676
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/212:53 pm -
1 stop14h 07m
Wed 12/161:10 pm -
2 stops16h 29m
Deal found 10/22![American Airlines logo]()
$681
This Finnair deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/67:49 am -
2 stops28h 06m
Mon 12/146:40 pm -
2 stops34h 41m
Deal found 10/24![Multiple Airlines logo]()
$694
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:00 am -
2 stops18h 45m
Wed 12/212:40 pm -
2 stops36h 35m
Deal found 10/22![United Airlines logo]()
$715
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/610:04 am -
1 stop19h 16m
Tue 12/1510:25 am -
1 stop15h 47m
Deal found 10/23![Delta logo]()
$722
This KLM deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1511:53 am -
1 stop17h 27m
Tue 11/246:10 am -
2 stops17h 00m
Deal found 10/22![KLM logo]()
$744
This Cheapflightsfares deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/93:03 pm -
2 stops19h 17m
Wed 12/166:30 am -
2 stops20h 29m
Deal found 10/25![Lufthansa logo]()
$798
This Air Canada deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:30 am -
3 stops21h 10m
Wed 12/166:30 am -
3 stops23h 10m
Deal found 10/25![Air Canada logo]()
$892
This British Airways deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/14:06 pm -
1 stop10h 54m
Mon 12/76:45 pm -
2 stops45h 44m
Deal found 10/25![British Airways logo]()
$706
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/610:00 am -
1 stop16h 30m
Tue 12/1511:15 am -
2 stops33h 12m
Deal found 10/23![United Airlines logo]()
$721
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/12:10 pm -
2 stops15h 20m
Thu 12/1010:25 am -
2 stops17h 36m
Deal found 10/22![American Airlines logo]()
$723
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:40 am -
2 stops20h 05m
Wed 11/2510:00 am -
2 stops19h 38m
Deal found 10/22![Delta logo]()
$727
This Finnair deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/67:00 am -
2 stops28h 55m
Sat 12/126:40 pm -
2 stops33h 43m
Deal found 10/26![Multiple Airlines logo]()
$752
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:00 am -
1 stop19h 45m
Thu 12/1710:30 am -
1 stop19h 29m
Deal found 10/26![United Airlines logo]()
$726
This KLM deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/1410:14 am -
1 stop18h 31m
Sat 2/2012:55 pm -
1 stop13h 19m
Deal found 10/26![KLM logo]()
$803
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/307:00 am -
1 stop22h 20m
Fri 12/1812:30 pm -
2 stops26h 54m
Deal found 10/26![Delta logo]()
$737
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/612:41 pm -
1 stop14h 19m
Mon 12/141:10 pm -
1 stop28h 21m
Deal found 10/24![American Airlines logo]()
$742
This KAYAK deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2311:58 am -
1 stop13h 32m
Mon 11/305:15 pm -
2 stops36h 25m
Deal found 10/25![Lufthansa logo]()
$852
This Finnair deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:45 am -
2 stops28h 30m
Mon 12/147:00 pm -
2 stops32h 52m
Deal found 10/23![Multiple Airlines logo]()
$788
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/110:23 am -
1 stop15h 07m
Thu 12/109:45 am -
1 stop20h 14m
Deal found 10/22![United Airlines logo]()
$728
This FlightHub deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/910:47 am -
2 stops19h 33m
Sun 3/1411:00 am -
1 stop13h 33m
Deal found 10/23![British Airways logo]()
$803
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/283:57 pm -
2 stops15h 43m
Fri 3/510:25 am -
1 stop14h 35m
Deal found 10/22![American Airlines logo]()
$762
This KLM deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2011:10 am -
1 stop17h 50m
Tue 4/2710:10 am -
2 stops19h 25m
Deal found 10/24![KLM logo]()
$846
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/226:00 am -
2 stops22h 45m
Mon 3/2212:45 pm -
2 stops26h 23m
Deal found 10/22![Delta logo]()
$795
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1710:37 am -
1 stop15h 08m
Wed 11/2510:30 am -
1 stop31h 11m
Deal found 10/27![United Airlines logo]()
$736
This KLM deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/92:15 pm -
1 stop12h 00m
Sun 3/148:45 pm -
2 stops26h 10m
Deal found 10/25![Multiple Airlines logo]()
$810
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/223:53 pm -
2 stops17h 02m
Mon 3/221:00 pm -
1 stop26h 18m
Deal found 10/22![American Airlines logo]()
$773
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/1212:00 pm -
2 stops16h 00m
Fri 2/196:30 am -
2 stops17h 11m
Deal found 10/22![Delta logo]()
$804
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/286:00 am -
1 stop19h 30m
Fri 3/512:55 pm -
2 stops34h 20m
Deal found 10/22![United Airlines logo]()
$743
Last-minute flights from South Carolina to ItalyDiscover last-minute flight deals from South Carolina to Italy. Data last updated October 27, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Italy. Data last updated October 27, 2026 and is based on user searches.
This British Airways deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/910:54 am -
1 stop16h 06m
Wed 11/2511:00 am -
1 stop29h 33m
Deal found 10/22![British Airways logo]()
$676
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/910:54 am -
1 stop16h 06m
Wed 11/2511:00 am -
2 stops18h 31m
Deal found 10/22![American Airlines logo]()
$681
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/113:35 pm -
1 stop13h 20m
Wed 11/189:45 am -
1 stop18h 15m
Deal found 10/23![United Airlines logo]()
$676
This Justfly.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:16 pm -
2 stops16h 39m
Wed 11/1811:00 am -
1 stop18h 18m
Deal found 10/23![British Airways logo]()
$683
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/118:12 am -
2 stops18h 48m
Wed 11/1811:00 am -
2 stops17h 51m
Deal found 10/23![American Airlines logo]()
$691
This Air Canada deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:00 am -
2 stops19h 55m
Wed 11/187:05 am -
3 stops22h 54m
Deal found 10/23![Multiple Airlines logo]()
$703
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:30 am -
1 stop21h 15m
Wed 11/2511:00 am -
2 stops18h 06m
Deal found 10/27![American Airlines logo]()
$691
This Expedia deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2312:54 pm -
1 stop15h 51m
Wed 12/26:40 pm -
2 stops33h 44m
Deal found 10/25![Finnair logo]()
$686
This FlightHub deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:00 am -
1 stop21h 45m
Wed 12/28:35 pm -
2 stops34h 06m
Deal found 10/25![British Airways logo]()
$706
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:00 am -
2 stops18h 45m
Wed 12/212:40 pm -
2 stops36h 35m
Deal found 10/22![United Airlines logo]()
$715
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/308:00 am -
1 stop20h 45m
Fri 12/181:10 pm -
1 stop27h 28m
Deal found 10/27![American Airlines logo]()
$692
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/3010:23 am -
1 stop16h 07m
Sat 12/1211:15 am -
2 stops34h 17m
Deal found 10/22![United Airlines logo]()
$711
One-way flights from South Carolina to ItalySearch for one-way flight options from South Carolina to Italy. Find affordable one-way fares based on user searches. Data last updated October 27, 2026.
Search for one-way flight options from South Carolina to Italy. Find affordable one-way fares based on user searches. Data last updated October 27, 2026.
This oojo deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/229:08 am -
1 stop17h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Lufthansa logo]()
$330
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/222:25 pm -
1 stop12h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Delta logo]()
$340
This FlightHub deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2211:01 am -
2 stops27h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![British Airways logo]()
$341
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/123:07 pm -
2 stops49h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![Multiple Airlines logo]()
$345
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/227:40 pm -
2 stops22h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![United Airlines logo]()
$347
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/163:20 pm -
2 stops58h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![United Airlines logo]()
$367
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:10 am -
3 stops30h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![Multiple Airlines logo]()
$389
This Expedia deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/166:30 pm -
1 stop33h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![British Airways logo]()
$394
This Expedia deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/62:54 pm -
2 stops23h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Lufthansa logo]()
$421
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/188:32 pm -
2 stops39h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Multiple Airlines logo]()
$432
This Cheapflightsfares deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:00 am -
2 stops22h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Aer Lingus logo]()
$434
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/312:13 pm -
2 stops20h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![Multiple Airlines logo]()
$454
Find flight deals from South Carolina to Italy
Keep the following information in mind while searching for South Carolina to Italy flight deals. Data was last updated October 27, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $668 (Expedia) |
One-way from | $330 (oojo) |
Popular in | July |
Cheapest in | January |
Average price | $997 |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 27, 2026.
Use the filters below to find and compare flights from South Carolina to Italy that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonRome
CHS Charleston - FCO Rome Fiumicino
CHSFCO
Charleston
Mon 3/22
9:08 am-7:45 am
1 stop17h 37m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$330
CharlestonRome
CHS Charleston - FCO Rome Fiumicino
CHSFCO
Charleston
Mon 3/22
2:25 pm-8:15 am
1 stop12h 50m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$340
CharlestonRome
CHS Charleston - FCO Rome Fiumicino
CHSFCO
Charleston
Mon 3/22
7:40 pm-11:10 pm
2 stops22h 30m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$347
Myrtle BeachRome
MYR Myrtle Beach Intl - FCO Rome Fiumicino
MYRFCO
Myrtle Beach Intl
Fri 4/16
3:20 pm-8:15 am
2 stops58h 55m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$367
GreenvilleFlorence
GSP Greenville - FLR Florence Peretola
GSPFLR
Greenville
Tue 4/6
2:54 pm-8:15 pm
2 stops23h 21m
Florence Peretola
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$421
GreenvilleRome
GSP Greenville - FCO Rome Fiumicino
GSPFCO
Greenville
Mon 1/18
8:32 pm-6:15 pm
2 stops39h 43m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$432
CharlestonMilan
CHS Charleston - MXP Milan Malpensa
CHSMXP
Charleston
Thu 12/31
2:13 pm-4:55 pm
2 stops20h 42m
Milan Malpensa
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$454
CharlestonFlorence
CHS Charleston - FLR Florence Peretola
CHSFLR
Charleston
Tue 1/12
3:07 pm-6:15 pm
3 stops45h 08m
Florence Peretola
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$471
CharlestonFlorence
CHS Charleston - FLR Florence Peretola
CHSFLR
Charleston
Mon 1/18
3:17 pm-11:35 am
3 stops38h 18m
Florence Peretola
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$476
CharlestonRome
CHS Charleston - FCO Rome Fiumicino
CHSFCO
Charleston
Thu 4/1
10:23 am-2:20 pm
2 stops21h 57m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$493
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Italy
Have a flexible travel schedule? Discover the best time to fly to Italy from South Carolina with our price prediction graph.
CHS-FCO
CHS-FLR
MYR-FCO
GSP-FLR
GSP-FCO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Italy
USSC-IT0
CHS-FCO
CHS-FLR
MYR-FCO
GSP-FLR
What is the cheapest month to book a flight from South Carolina to Italy?
Currently, February is the cheapest month in which you can book a flight from South Carolina to Italy (average of $527). Flying from South Carolina to Italy in June is currently the most expensive (average of $1,558). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from South Carolina to Italy?
The price you pay for your flight from South Carolina to Italy may vary depending on when you book. For the best chance of a lower fare, look to book 48 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for South Carolina to Italy
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Italy by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Italy by cabin class
Find flights from South Carolina to Italy, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Carolina and Italy flights
Browse other South Carolina and Italy flight options. Last updated on October 27, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Italy
Find the right flight back to South Carolina after your stay in Italy
South Carolina to Italy flights
Consider these flights traveling from South Carolina to Italy.
Fly to Italy regions
Consider these flights traveling to Italy regions.
Top 5 airlines flying from South Carolina to Italy
Discover the top 5 airlines that operate flights from South Carolina to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$497 | Average$1,353 | FlexibilityNo cancel fee | On-time76% | |
| Cheapest$503 | Average$1,268 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$609 | Average$1,175 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$616 | Average$1,203 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$759 | Average$1,315 | FlexibilityNo cancel fee | On-time71% |