What are the cheapest airlines to fly from South Carolina to Italy one-way?

$373 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on KLM and British Airways, with prices starting from $374 and $378, respectively.

What is the cheapest month to fly from South Carolina to Italy?

February can be a great time to fly to Italy from South Carolina with a flight ticket averaging about $1,212. Cheapflights users have found deals in the month of February for as cheap as $691. The most expensive prices can be found in the month of June.

Can I find deals for flights from South Carolina to Italy that include hotel bookings?

Yes. In addition to deals on South Carolina to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from South Carolina to Italy?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Italy.

Can I find deals for business class flights from South Carolina to Italy?

Yes. Cheapflights offers flight deals from South Carolina to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$667+ Flights from South Carolina to Italy - Compare & Save Big

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Cheap flight deals from South Carolina to Italy

Most accurate provider	AranGrant 3 stars
Most trusted provider	AranGrant 3 stars
Round-trip from	$607 (FlightHub)
One-way from	$285 (Kiwi.com)
Popular in	June
Cheapest in	February
Average price	$1,120

Provider with most accurate pricing for Myrtle Beach Intl-Rome (ROM) flight deals.

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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Rome (ROM) flights.

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From South Carolina to Italy

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One-way flight from South Carolina to Italy

Search Deals

Highest demand for flights based on searches. 28% potential increase in price ($470 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 5% potential price decrease ($64 potential savings vs. average RT price).

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Average for round-trip flights in April 2025

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Find flight deals from South Carolina to Italy

Cheapest flights from South Carolina to Italy
Explore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.

Tue 9/2310:25 amCLT - VCE

2 stops17h 35mScandinavian Airlines

Tue 10/2811:20 amVCE - CLT

2 stops41h 34mScandinavian Airlines

Deal found 4/28

$607

Fri 10/241:02 pmCHS - FCO

1 stop19h 28mMultiple Airlines

Fri 11/77:10 pmFCO - CHS

1 stop22h 57mMultiple Airlines

Deal found 4/29

$617

Mon 12/82:30 pmCLT - VCE

1 stop12h 25mMultiple Airlines

Fri 1/910:25 amVCE - CLT

2 stops16h 34mMultiple Airlines

Deal found 4/29

$633

Mon 12/82:30 pmCLT - VCE

1 stop12h 25mUnited Airlines

Fri 1/96:30 amVCE - CLT

1 stop16h 25mUnited Airlines

Deal found 4/29

$637

Fri 10/244:55 pmCHS - FCO

2 stops58h 00mAir Canada

Fri 11/71:15 pmFCO - CHS

2 stops27h 06mAir Canada

Deal found 4/29

$642

Wed 11/122:54 pmGSP - FCO

1 stop11h 36mUnited Airlines

Tue 11/1812:55 pmFCO - GSP

1 stop14h 54mUnited Airlines

Deal found 4/27

$644

Sat 9/2711:50 pmCLT - NAP

1 stop16h 10mAmerican Airlines

Tue 10/73:00 pmNAP - CLT

1 stop23h 17mAmerican Airlines

Deal found 4/28

$645

Wed 8/138:30 amCLT - NAP

2 stops19h 10mAir Canada

Thu 8/2111:35 amNAP - CLT

2 stops35h 40mAir Canada

Deal found 4/28

$648

Tue 8/126:45 amCLT - NAP

2 stops20h 55mUnited Airlines

Wed 8/202:00 pmNAP - CLT

1 stop14h 45mUnited Airlines

Deal found 4/28

$650

Sat 9/276:00 amCLT - NAP

2 stops20h 10mDelta

Tue 10/710:15 amNAP - CLT

2 stops18h 05mDelta

Deal found 4/28

$651

Tue 8/1210:29 amCLT - NAP

2 stops17h 11mMultiple Airlines

Wed 8/207:15 pmNAP - CLT

2 stops28h 00mMultiple Airlines

Deal found 4/28

$655

Tue 10/288:20 pmCLT - VCE

2 stops15h 35mBritish Airways

Mon 11/105:50 pmVCE - CLT

2 stops29h 08mBritish Airways

Deal found 4/27

$659

Best flights from South Carolina to Italy
Discover carefully curated flight deals from South Carolina to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 30, 2025.

Tue 9/2310:25 amCLT - VCE

2 stops17h 35mScandinavian Airlines

Tue 10/2811:20 amVCE - CLT

2 stops41h 34mScandinavian Airlines

Deal found 4/28

$607

Thu 10/1610:55 amCLT - NAP

1 stop15h 15mDelta

Mon 10/206:10 amNAP - CLT

2 stops21h 55mDelta

Deal found 4/29

$622

Thu 8/216:40 pmCLT - NAP

1 stop15h 55mUnited Airlines

Sun 9/711:35 amNAP - CLT

2 stops40h 02mUnited Airlines

Deal found 4/29

$644

Sat 9/2711:45 amCLT - NAP

1 stop13h 15mKLM

Tue 10/710:15 amNAP - CLT

1 stop14h 20mKLM

Deal found 4/29

$646

Sat 9/276:36 amCLT - NAP

2 stops21h 04mAir Canada

Sat 10/46:40 amNAP - CLT

2 stops20h 42mAir Canada

Deal found 4/29

$651

Sat 9/2710:34 amCLT - NAP

2 stops17h 06mMultiple Airlines

Tue 10/76:00 amNAP - CLT

1 stop16h 45mMultiple Airlines

Deal found 4/29

$655

Wed 5/147:40 pmCLT - NAP

2 stops14h 55mLufthansa

Thu 10/169:00 amNAP - CLT

1 stop13h 45mLufthansa

Deal found 4/29

$676

Tue 5/1310:41 amCLT - NAP

2 stops16h 04mSWISS

Tue 10/142:50 pmNAP - CLT

2 stops32h 15mSWISS

Deal found 4/29

$681

Sun 9/2810:35 amCLT - NAP

2 stops40h 25mAustrian Airlines

Sun 10/59:50 amNAP - CLT

2 stops41h 47mAustrian Airlines

Deal found 4/29

$692

Tue 5/1311:04 amCLT - NAP

1 stop19h 56mAmerican Airlines

Wed 10/1512:00 pmNAP - CLT

1 stop15h 39mAmerican Airlines

Deal found 4/29

$695

Thu 10/1612:09 pmGSP - FCO

1 stop13h 56mFinnair

Wed 10/226:55 pmFCO - GSP

2 stops32h 55mFinnair

Deal found 4/27

$777

Sat 5/1710:39 amCHS - FCO

2 stops30h 51mTurkish Airlines

Sat 5/247:00 amFCO - CHS

2 stops41h 01mTurkish Airlines

Deal found 4/29

$815

Last-minute flights from South Carolina to Italy
Discover last-minute flight deals from South Carolina to Italy. Data last updated April 30, 2025 and is based on user searches.

Sun 5/48:30 amCLT - NAP

2 stops26h 05mAir Canada

Tue 5/206:40 amNAP - CLT

2 stops20h 41mAir Canada

Deal found 4/29

$936

Sun 5/46:00 amCLT - NAP

2 stops19h 00mUnited Airlines

Tue 5/209:45 amNAP - CLT

1 stop18h 00mUnited Airlines

Deal found 4/29

$938

Mon 5/58:41 amCLT - MXP

3 stops32h 39mMultiple Airlines

Sun 5/118:35 amMXP - CLT

2 stops44h 03mMultiple Airlines

Deal found 4/28

$884

Mon 5/52:52 pmCLT - MXP

2 stops16h 28mUnited Airlines

Sun 5/119:45 amMXP - CLT

1 stop12h 49mUnited Airlines

Deal found 4/28

$927

Mon 5/56:40 pmCLT - LIN

1 stop17h 10mMultiple Airlines

Sun 5/117:00 amLIN - CLT

2 stops20h 21mMultiple Airlines

Deal found 4/28

$943

Tue 5/61:55 pmCLT - MXP

1 stop16h 10mDelta

Sat 5/179:00 amMXP - CLT

2 stops20h 52mDelta

Deal found 4/28

$931

Tue 5/68:05 pmCLT - LIN

1 stop11h 30mAmerican Airlines

Sat 5/178:30 pmLIN - CLT

1 stop23h 50mAmerican Airlines

Deal found 4/28

$941

Wed 5/78:05 pmCLT - NAP

1 stop19h 50mAmerican Airlines

Wed 5/2112:00 pmNAP - CLT

1 stop17h 20mAmerican Airlines

Deal found 4/28

$944

Thu 5/84:43 pmCLT - NAP

2 stops35h 57mAer Lingus

Wed 5/1411:40 amNAP - CLT

2 stops26h 27mAer Lingus

Deal found 4/27

$875

Fri 5/98:38 amCLT - FCO

1 stop23h 52mMultiple Airlines

Sun 5/187:05 pmFCO - CLT

1 stop24h 37mMultiple Airlines

Deal found 4/29

$739

Fri 5/911:52 amCLT - FLR

3 stops24h 38mMultiple Airlines

Sun 5/187:55 pmFLR - CLT

3 stops26h 52mMultiple Airlines

Deal found 4/29

$828

Fri 5/96:35 pmCLT - MXP

1 stop22h 25mAmerican Airlines

Mon 5/1911:10 amMXP - CLT

1 stop12h 20mAmerican Airlines

Deal found 4/28

$926

One-way flights from South Carolina to Italy
Search for one-way flight options from South Carolina to Italy. Find affordable one-way fares based on user searches. Data last updated April 30, 2025.

Wed 7/236:32 pmCLT - FCO

1 stop13h 58mMultiple Airlines

Deal found 4/29

$285

Mon 7/142:50 pmGSP - FCO

2 stops28h 05mMultiple Airlines

Deal found 4/28

$308

Thu 7/173:57 pmCLT - MXP

2 stops16h 43mMultiple Airlines

Deal found 4/27

$346

Mon 9/293:57 pmCLT - VCE

2 stops17h 43mMultiple Airlines

Deal found 4/28

$351

Sun 6/85:45 amCLT - NAP

2 stops52h 25mMultiple Airlines

Deal found 4/28

$369

Thu 7/176:40 pmCLT - LIN

1 stop16h 35mAmerican Airlines

Deal found 4/27

$373

Thu 7/1711:15 amCLT - MXP

1 stop16h 10mKLM

Deal found 4/27

$374

Thu 7/171:00 pmCLT - LIN

2 stops22h 15mBritish Airways

Deal found 4/27

$378

Thu 7/1712:37 pmCLT - LIN

3 stops24h 18mMultiple Airlines

Deal found 4/27

$397

Sat 5/109:35 amCHS - FCO

1 stop27h 35mMultiple Airlines

Deal found 4/29

$414

Mon 5/126:35 pmCLT - MXP

1 stop20h 10mAmerican Airlines

Deal found 4/28

$472

Thu 5/156:54 pmCHS - FCO

2 stops22h 36mTurkish Airlines

Deal found 4/29

$478

Cheapflights Fare Finder

Use the filters below to find and compare flights from South Carolina to Italy that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteVenice

CLT - VCE

CLTVCE

Charlotte Douglas

Tue 9/23

10:25 am-10:00 am

2 stops17h 35m

Venice Marco Polo

Tue 10/28

11:20 am-11:54 pm

2 stops41h 34m

$607

CharlotteNaples

CLT - NAP

CLTNAP

Charlotte Douglas

Sat 9/27

11:50 pm-10:00 pm

1 stop16h 10m

Naples

Tue 10/7

3:00 pm-8:17 am

1 stop23h 17m

$645

CharlotteNaples

CLT - NAP

CLTNAP

Charlotte Douglas

Wed 8/13

8:30 am-9:40 am

2 stops19h 10m

Naples

Thu 8/21

11:35 am-5:15 pm

2 stops35h 40m

$648

CharlotteNaples

CLT - NAP

CLTNAP

Charlotte Douglas

Tue 8/12

6:45 am-9:40 am

2 stops20h 55m

Naples

Wed 8/20

2:00 pm-10:45 pm

1 stop14h 45m

$650

CharlotteNaples

CLT - NAP

CLTNAP

Charlotte Douglas

Sat 9/27

6:00 am-8:10 am

2 stops20h 10m

Naples

Tue 10/7

10:15 am-10:20 pm

2 stops18h 05m

$651

CharlotteNaples

CLT - NAP

CLTNAP

Charlotte Douglas

Tue 8/12

10:29 am-9:40 am

2 stops17h 11m

Naples

Wed 8/20

7:15 pm-5:15 pm

2 stops28h 00m

$655

CharlotteNaples

CLT - NAP

CLTNAP

Charlotte Douglas

Fri 10/3

8:10 pm-10:00 pm

1 stop19h 50m

Naples

Sat 10/11

7:50 am-8:11 pm

2 stops18h 21m

$673

SavannahRome

SAV - FCO

SAVFCO

Savannah/Hilton Head

Sun 10/19

9:44 am-1:15 pm

1 stop21h 31m

Rome Fiumicino

Sat 11/1

10:10 am-7:52 pm

2 stops38h 42m

$678

CharlotteRome

CLT - FCO

CLTFCO

Charlotte Douglas

Wed 10/8

6:32 pm-2:30 pm

1 stop13h 58m

Rome Fiumicino

Tue 10/21

7:05 pm-11:30 pm

1 stop34h 25m

$683

SavannahRome

SAV - FCO

SAVFCO

Savannah/Hilton Head

Mon 9/29

11:45 am-6:20 am

1 stop12h 35m

Rome Fiumicino

Tue 10/7

10:15 am-9:26 pm

1 stop17h 11m

$687

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Showing 1-10 of 60 results

...

Best time to book a flight from South Carolina to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from South Carolina with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Italy

What is the cheapest month to book a flight from South Carolina to Italy?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Italy (average of $703). Flying from South Carolina to Italy in June is currently the most expensive (average of $1,238). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to IT?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Italy as you normally would.

Rainfall in Italy by month

In terms of precipitation, rainfall in Italy ranges from 0.6 - 4.4 inches per month. November is typically the wettest month, when rainfall can reach 4.4 in. June is typically the driest time to visit Italy when rainfall is around 0.6 in.

Temperature in Italy by month

If weather is an important factor for your trip to Italy, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Italy

Read reviews from past customers who have flown Delta, KLM and Finnair from South Carolina to Italy. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,936 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta

8.0

Very good

7,936 reviews

Delta

8.0

Very good

7,936 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

KLM

7.8

Good

1,333 reviews

Delta

8.0

Very good

7,936 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Finnair

7.6

Good

1,273 reviews

Delta

8.0

Very good

7,936 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Austrian Airlines

7.6

Good

780 reviews

Delta

8.0

Very good

7,936 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

SWISS

7.5

Good

1,588 reviews

Delta

8.0

Very good

7,936 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

What are the cheapest airlines to fly from South Carolina to Italy one-way?
$373 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on KLM and British Airways, with prices starting from $374 and $378, respectively.
Can I find deals for flights from South Carolina to Italy that include hotel bookings?
Yes. In addition to deals on South Carolina to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from South Carolina to Italy?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Italy.
Can I find deals for business class flights from South Carolina to Italy?
Yes. Cheapflights offers flight deals from South Carolina to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from South Carolina to Italy?
Currently, January is the cheapest month in which you can book a flight from South Carolina to Italy (average of $703). Flying from South Carolina to Italy in June is currently the most expensive (average of $1,238). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 7 airlines flying from South Carolina to Italy

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$626	Average$1,157	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$628	Average$1,268	FlexibilityNo cancel fee	On-time71%
Lufthansa	Cheapest$651	Average$1,533	FlexibilityNo cancel fee	On-time76%
KLM	Cheapest$655	Average$1,234	FlexibilityNo cancel fee	On-time75%
United Airlines	Cheapest$665	Average$1,151	FlexibilityNo cancel fee	On-time69%
British Airways	Cheapest$744	Average$1,261	FlexibilityNo cancel fee	On-time70%
Air Canada	Cheapest$1,063	Average$1,188	FlexibilityNo cancel fee	On-time67%

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$285+ Cheap flights from South Carolina to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/23. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from South Carolina to Italy with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from South Carolina to Italy

Keep the following information in mind while searching for South Carolina to Italy flight deals. Data was last updated April 30, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from South Carolina to Italy

Cheapest flights from South Carolina to ItalyExplore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.

Explore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from South Carolina to Italy that are best for you.

Best time to book a flight from South Carolina to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from South Carolina with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Italy

What is the cheapest month to book a flight from South Carolina to Italy?

What is the cheapest time of day to fly from SC to IT?

Find hourly flight availability from South Carolina to Italy. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 30, 2025.

Rainfall in Italy by month

Plan your trip to Italy by taking into account the average rainfall totals by month.

Temperature in Italy by month

Plan your trip to Italy by taking into account the average temperature totals by month.

Reviews of airlines servicing Italy

Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated April 30, 2025.

Read reviews from past customers who have flown Delta, KLM and Finnair from South Carolina to Italy. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines to fly from South Carolina to Italy one-way?

Can I find deals for flights from South Carolina to Italy that include hotel bookings?

How can I find direct flights from South Carolina to Italy?

Can I find deals for business class flights from South Carolina to Italy?

What is the cheapest month to book a flight from South Carolina to Italy?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Italy

See prices for flight routes from nearby airports that may be better suited for you.

Top 7 airlines flying from South Carolina to Italy

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Travel Smart

Cheapest flights from South Carolina to Italy
Explore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.