$336+ Cheap flights from South Carolina to Italy
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/15. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — FCO
Nov 21 — Nov 281
Round-trip
1 adult, Economy
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Find cheap flights from South Carolina to Italy with Cheapflights
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Cheapest flights from South Carolina to ItalyExplore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 22, 2026.
Explore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 22, 2026.
This Mytrip deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:56 pm -
2 stops30h 59m
Tue 12/811:15 am -
2 stops42h 44m
Deal found 10/18![Air Canada logo]()
$664
This Justfly.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:00 pm -
2 stops33h 55m
Thu 12/311:15 am -
2 stops40h 06m
Deal found 10/19![Air Canada logo]()
$669
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:04 pm -
2 stops15h 51m
Thu 12/31:10 pm -
1 stop16h 16m
Deal found 10/19![American Airlines logo]()
$673
This British Airways deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/62:33 pm -
2 stops21h 17m
Tue 12/151:10 pm -
1 stop35h 12m
Deal found 10/17![British Airways logo]()
$673
This British Airways deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:55 am -
2 stops22h 25m
Tue 12/81:10 pm -
1 stop27h 19m
Deal found 10/18![British Airways logo]()
$673
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:03 pm -
2 stops17h 52m
Wed 11/2511:00 am -
1 stop13h 16m
Deal found 10/21![American Airlines logo]()
$674
This Air Canada deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:00 pm -
2 stops33h 55m
Thu 11/2611:15 am -
2 stops32h 41m
Deal found 10/18![Air Canada logo]()
$675
This Finnair deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2312:54 pm -
1 stop15h 51m
Wed 12/26:40 pm -
2 stops33h 44m
Deal found 10/20![Finnair logo]()
$676
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:28 pm -
2 stops15h 52m
Tue 11/2411:00 am -
2 stops18h 55m
Deal found 10/18![American Airlines logo]()
$678
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:21 pm -
2 stops17h 34m
Wed 11/2511:00 am -
2 stops18h 06m
Deal found 10/18![American Airlines logo]()
$678
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/18:35 pm -
2 stops17h 05m
Tue 12/81:10 pm -
2 stops15h 51m
Deal found 10/18![American Airlines logo]()
$678
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/25:34 pm -
2 stops17h 21m
Wed 12/161:10 pm -
1 stop28h 57m
Deal found 10/20![American Airlines logo]()
$679
Best flights from South Carolina to ItalyDiscover carefully curated flight deals from South Carolina to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 22, 2026.
Discover carefully curated flight deals from South Carolina to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 22, 2026.
This British Airways deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/62:33 pm -
2 stops21h 17m
Tue 12/151:10 pm -
1 stop35h 12m
Deal found 10/17![British Airways logo]()
$673
This British Airways deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/13:58 pm -
2 stops17h 32m
Tue 12/81:10 pm -
1 stop34h 29m
Deal found 10/18![Multiple Airlines logo]()
$690
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:00 am -
1 stop19h 30m
Wed 12/99:45 am -
1 stop19h 55m
Deal found 10/17![United Airlines logo]()
$718
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/112:24 pm -
2 stops15h 36m
Thu 12/1012:55 pm -
1 stop17h 09m
Deal found 10/17![Delta logo]()
$722
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/12:10 pm -
2 stops15h 20m
Thu 12/1010:25 am -
2 stops17h 36m
Deal found 10/20![American Airlines logo]()
$723
This Justfly.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/103:23 pm -
2 stops25h 22m
Fri 2/1910:45 am -
2 stops18h 34m
Deal found 10/20![Lufthansa logo]()
$751
This Air Canada deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:30 am -
3 stops21h 10m
Wed 12/96:30 am -
3 stops23h 10m
Deal found 10/18![Air Canada logo]()
$850
This KLM deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/512:52 pm -
2 stops15h 48m
Sun 3/146:50 am -
2 stops18h 52m
Deal found 10/17![KLM logo]()
$856
This Turkish Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/222:40 pm -
2 stops44h 10m
Mon 12/283:10 pm -
2 stops37h 28m
Deal found 10/19![Turkish Airlines logo]()
$1,085
This Finnair deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/152:10 pm -
2 stops25h 45m
Mon 3/16:40 pm -
2 stops34h 00m
Deal found 10/21![Multiple Airlines logo]()
$718
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/3010:56 am -
2 stops17h 49m
Fri 12/1810:25 am -
1 stop15h 32m
Deal found 10/20![Delta logo]()
$725
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1710:37 am -
1 stop15h 08m
Wed 11/2510:30 am -
1 stop31h 11m
Deal found 10/18![United Airlines logo]()
$726
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:17 pm -
2 stops16h 53m
Thu 12/101:10 pm -
2 stops16h 46m
Deal found 10/19![American Airlines logo]()
$728
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2312:18 pm -
2 stops16h 37m
Wed 12/22:10 pm -
2 stops35h 05m
Deal found 10/22![United Airlines logo]()
$727
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/612:41 pm -
1 stop14h 19m
Sun 12/131:10 pm -
2 stops16h 29m
Deal found 10/22![American Airlines logo]()
$731
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/157:00 am -
2 stops19h 15m
Thu 3/46:10 am -
2 stops20h 55m
Deal found 10/18![Delta logo]()
$744
This KAYAK deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:37 pm -
1 stop13h 38m
Mon 11/305:15 pm -
2 stops36h 25m
Deal found 10/18![Lufthansa logo]()
$847
This FlightHub deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1211:04 am -
2 stops18h 26m
Mon 4/1912:40 pm -
2 stops36h 25m
Deal found 10/17![British Airways logo]()
$860
This KLM deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/412:18 pm -
1 stop16h 27m
Thu 12/176:30 am -
2 stops18h 00m
Deal found 10/22![Multiple Airlines logo]()
$797
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/110:23 am -
1 stop15h 07m
Thu 12/109:45 am -
1 stop20h 14m
Deal found 10/20![United Airlines logo]()
$728
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1812:42 pm -
1 stop14h 18m
Wed 11/251:10 pm -
1 stop16h 13m
Deal found 10/21![American Airlines logo]()
$738
This KLM deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/95:25 pm -
1 stop12h 40m
Fri 4/1611:40 am -
1 stop16h 06m
Deal found 10/17![KLM logo]()
$894
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/234:30 pm -
1 stop13h 50m
Thu 4/11:10 pm -
1 stop26h 32m
Deal found 10/20![Delta logo]()
$760
This FlightHub deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:43 pm -
2 stops19h 27m
Mon 11/165:15 pm -
2 stops36h 32m
Deal found 10/17![Lufthansa logo]()
$850
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1812:22 pm -
1 stop16h 33m
Wed 11/259:45 am -
1 stop34h 22m
Deal found 10/21![United Airlines logo]()
$736
This FlightHub deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:40 am -
3 stops22h 25m
Mon 11/305:15 pm -
2 stops36h 25m
Deal found 10/17![Multiple Airlines logo]()
$815
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/223:53 pm -
2 stops17h 02m
Mon 3/221:00 pm -
1 stop26h 18m
Deal found 10/21![American Airlines logo]()
$773
This KLM deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/112:25 pm -
1 stop14h 20m
Fri 1/2212:00 pm -
1 stop14h 42m
Deal found 10/19![KLM logo]()
$956
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/412:18 pm -
1 stop16h 27m
Thu 12/1712:55 pm -
1 stop30h 27m
Deal found 10/22![Delta logo]()
$800
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/307:43 pm -
2 stops36h 17m
Fri 12/1810:30 am -
2 stops29h 38m
Deal found 10/20![United Airlines logo]()
$737
Last-minute flights from South Carolina to ItalyDiscover last-minute flight deals from South Carolina to Italy. Data last updated October 22, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Italy. Data last updated October 22, 2026 and is based on user searches.
This Air Canada deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:00 pm -
2 stops33h 55m
Thu 11/2611:15 am -
2 stops32h 41m
Deal found 10/18![Air Canada logo]()
$675
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/162:52 pm -
1 stop11h 38m
Thu 11/2611:00 am -
1 stop29h 06m
Deal found 10/18![United Airlines logo]()
$682
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:28 pm -
2 stops15h 52m
Tue 11/2411:00 am -
2 stops18h 55m
Deal found 10/18![American Airlines logo]()
$678
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:21 pm -
2 stops17h 34m
Wed 11/2511:00 am -
2 stops18h 06m
Deal found 10/18![American Airlines logo]()
$678
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:03 pm -
2 stops17h 52m
Wed 11/2511:00 am -
1 stop13h 16m
Deal found 10/21![American Airlines logo]()
$674
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:00 am -
2 stops19h 30m
Thu 11/267:05 am -
2 stops32h 07m
Deal found 10/18![United Airlines logo]()
$703
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:58 am -
1 stop13h 57m
Wed 11/251:15 pm -
2 stops30h 25m
Deal found 10/21![United Airlines logo]()
$716
This Justfly.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:00 pm -
2 stops33h 55m
Thu 12/311:15 am -
2 stops40h 06m
Deal found 10/19![Air Canada logo]()
$669
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:04 pm -
2 stops15h 51m
Thu 12/31:10 pm -
1 stop16h 16m
Deal found 10/19![American Airlines logo]()
$673
This Finnair deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2312:54 pm -
1 stop15h 51m
Wed 12/26:40 pm -
2 stops33h 44m
Deal found 10/20![Finnair logo]()
$676
This FlightHub deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/297:58 am -
1 stop19h 02m
Wed 12/91:10 pm -
1 stop27h 19m
Deal found 10/21![British Airways logo]()
$687
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/308:00 am -
1 stop20h 45m
Wed 12/91:10 pm -
2 stops15h 51m
Deal found 10/21![American Airlines logo]()
$681
One-way flights from South Carolina to ItalySearch for one-way flight options from South Carolina to Italy. Find affordable one-way fares based on user searches. Data last updated October 22, 2026.
Search for one-way flight options from South Carolina to Italy. Find affordable one-way fares based on user searches. Data last updated October 22, 2026.
This Justfly.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/153:37 pm -
2 stops22h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![British Airways logo]()
$336
This Expedia deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/2512:35 pm -
2 stops25h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Lufthansa logo]()
$337
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/155:20 pm -
2 stops14h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![American Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/2511:57 am -
3 stops17h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![American Airlines logo]()
$339
This oojo deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/162:40 pm -
1 stop11h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/18![Lufthansa logo]()
$339
This KLM deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2212:15 pm -
1 stop15h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![KLM logo]()
$340
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/1510:00 am -
2 stops15h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/18![United Airlines logo]()
$340
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/226:30 pm -
2 stops15h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Delta logo]()
$344
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/1411:55 am -
2 stops21h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/18![Delta logo]()
$344
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/227:40 pm -
2 stops22h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![United Airlines logo]()
$347
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/275:10 pm -
2 stops36h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/18![Delta logo]()
$355
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/185:40 am -
2 stops23h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/18![Delta logo]()
$390
Find flight deals from South Carolina to Italy
Keep the following information in mind while searching for South Carolina to Italy flight deals. Data was last updated October 22, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $664 (Mytrip) |
One-way from | $336 (Justfly.com) |
Popular in | July |
Cheapest in | January |
Average price | $997 |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 22, 2026.
Use the filters below to find and compare flights from South Carolina to Italy that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonRome
CHS Charleston - FCO Rome Fiumicino
CHSFCO
Charleston
Mon 3/22
10:15 am-8:30 am
1 stop17h 15m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$339
GreenvilleFlorence
GSP Greenville - FLR Florence Peretola
GSPFLR
Greenville
Mon 1/25
11:57 am-11:30 am
3 stops17h 33m
Florence Peretola
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$339
CharlestonRome
CHS Charleston - FCO Rome Fiumicino
CHSFCO
Charleston
Mon 3/15
3:57 pm-9:50 am
1 stop12h 53m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$340
CharlestonRome
CHS Charleston - FCO Rome Fiumicino
CHSFCO
Charleston
Mon 3/22
2:25 pm-8:15 am
1 stop12h 50m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$340
CharlestonRome
CHS Charleston - FCO Rome Fiumicino
CHSFCO
Charleston
Mon 3/22
12:15 pm-8:15 am
1 stop15h 00m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$340
ColumbiaRome
CAE Columbia Metropolitan - FCO Rome Fiumicino
CAEFCO
Columbia Metropolitan
Tue 3/2
6:15 am-8:30 am
2 stops20h 15m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$340
ColumbiaRome
CAE Columbia Metropolitan - FCO Rome Fiumicino
CAEFCO
Columbia Metropolitan
Mon 3/1
2:40 pm-8:30 am
1 stop11h 50m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$340
ColumbiaRome
CAE Columbia Metropolitan - FCO Rome Fiumicino
CAEFCO
Columbia Metropolitan
Wed 2/17
7:00 am-8:15 am
2 stops19h 15m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$340
ColumbiaRome
CAE Columbia Metropolitan - FCO Rome Fiumicino
CAEFCO
Columbia Metropolitan
Sun 2/14
11:55 am-3:00 pm
2 stops21h 05m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$344
CharlestonRome
CHS Charleston - FCO Rome Fiumicino
CHSFCO
Charleston
Mon 3/22
7:40 pm-11:10 pm
2 stops22h 30m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$347
Showing 1-10 of 56 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Italy
Have a flexible travel schedule? Discover the best time to fly to Italy from South Carolina with our price prediction graph.
CHS-FCO
GSP-FLR
CAE-FCO
GSP-FCO
GSP-MXP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Italy
USSC-IT0
CHS-FCO
GSP-FLR
CAE-FCO
GSP-FCO
What is the cheapest month to book a flight from South Carolina to Italy?
Currently, February is the cheapest month in which you can book a flight from South Carolina to Italy (average of $526). Flying from South Carolina to Italy in June is currently the most expensive (average of $1,554). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Top regions
Alternative routes for South Carolina to Italy
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Italy by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Italy by cabin class
Find flights from South Carolina to Italy, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Carolina and Italy flights
Browse other South Carolina and Italy flight options. Last updated on October 22, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Italy
Find the right flight back to South Carolina after your stay in Italy
South Carolina to Italy flights
Consider these flights traveling from South Carolina to Italy.
Fly to Italy regions
Consider these flights traveling to Italy regions.
Top 5 airlines flying from South Carolina to Italy
Discover the top 5 airlines that operate flights from South Carolina to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$497 | Average$1,362 | FlexibilityNo cancel fee | On-time76% | |
| Cheapest$503 | Average$1,268 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$609 | Average$1,175 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$616 | Average$1,204 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$759 | Average$1,315 | FlexibilityNo cancel fee | On-time71% |