$300+ Cheap flights from South Carolina to Italy
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/7. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — NAP
Nov 1 — Nov 81
Round-trip
1 adult, Economy
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Find cheap flights from South Carolina to Italy with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from South Carolina to ItalyExplore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 2, 2026.
Explore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 2, 2026.
This Gotogate deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:20 am -
3 stops21h 45m
Tue 12/812:55 pm -
2 stops38h 04m
Deal found 9/30![Air Canada logo]()
$699
This Air France deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2312:12 pm -
1 stop16h 33m
Tue 12/812:55 pm -
1 stop15h 27m
Deal found 9/30![Air France logo]()
$711
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1012:18 pm -
1 stop13h 27m
Tue 11/1711:15 am -
2 stops32h 41m
Deal found 9/26![United Airlines logo]()
$711
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/110:23 am -
1 stop15h 07m
Thu 12/109:45 am -
1 stop34h 35m
Deal found 9/30![United Airlines logo]()
$711
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2311:58 am -
1 stop13h 32m
Tue 12/810:30 am -
2 stops16h 29m
Deal found 9/30![United Airlines logo]()
$713
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/88:32 pm -
2 stops15h 18m
Tue 11/241:10 pm -
1 stop35h 19m
Deal found 10/1![American Airlines logo]()
$715
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/12:10 pm -
2 stops15h 20m
Thu 12/1010:25 am -
2 stops17h 36m
Deal found 9/30![American Airlines logo]()
$716
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:21 pm -
2 stops15h 34m
Wed 11/1811:00 am -
2 stops17h 59m
Deal found 9/27![American Airlines logo]()
$716
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/810:23 am -
1 stop16h 07m
Tue 11/2410:30 am -
1 stop19h 29m
Deal found 10/1![United Airlines logo]()
$718
This Expedia deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:05 pm -
1 stop11h 15m
Wed 11/1810:25 am -
1 stop19h 28m
Deal found 9/27![Air France logo]()
$719
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:27 am -
1 stop17h 28m
Wed 11/187:05 am -
2 stops33h 16m
Deal found 9/28![United Airlines logo]()
$724
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/227:54 pm -
1 stop30h 36m
Thu 12/39:55 am -
2 stops34h 32m
Deal found 9/28![United Airlines logo]()
$724
Best flights from South Carolina to ItalyDiscover carefully curated flight deals from South Carolina to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 2, 2026.
Discover carefully curated flight deals from South Carolina to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 2, 2026.
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/110:23 am -
1 stop15h 07m
Thu 12/109:45 am -
1 stop34h 35m
Deal found 9/27![United Airlines logo]()
$711
This KLM deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1012:58 pm -
1 stop13h 17m
Tue 11/1711:45 am -
1 stop14h 39m
Deal found 9/26![KLM logo]()
$727
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/911:53 am -
1 stop17h 27m
Tue 11/1710:25 am -
1 stop19h 28m
Deal found 10/1![Delta logo]()
$727
This American Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/161:29 pm -
1 stop13h 31m
Mon 11/2311:00 am -
1 stop13h 16m
Deal found 10/2![American Airlines logo]()
$777
This United deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:00 am -
2 stops21h 05m
Sun 11/151:05 pm -
3 stops34h 34m
Deal found 9/30![Multiple Airlines logo]()
$829
This Justfly.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:20 am -
2 stops21h 45m
Mon 11/3012:55 pm -
2 stops33h 58m
Deal found 9/29![Air Canada logo]()
$835
This Turkish Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1310:50 am -
2 stops45h 00m
Fri 11/202:50 pm -
2 stops38h 49m
Deal found 9/29![Turkish Airlines logo]()
$864
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/126:00 am -
1 stop19h 30m
Thu 1/219:45 am -
1 stop19h 34m
Deal found 9/27![United Airlines logo]()
$716
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:50 pm -
2 stops14h 05m
Thu 11/1912:55 pm -
1 stop16h 58m
Deal found 9/28![Delta logo]()
$765
This KAYAK deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/257:37 pm -
2 stops21h 08m
Sat 1/26:40 am -
2 stops18h 22m
Deal found 9/26![Lufthansa logo]()
$1,551
This KLM deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1310:52 am -
1 stop18h 28m
Fri 11/2010:25 am -
1 stop18h 29m
Deal found 9/29![KLM logo]()
$777
This British Airways deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2210:32 am -
1 stop17h 23m
Thu 10/2912:15 pm -
1 stop27h 29m
Deal found 9/27![British Airways logo]()
$1,586
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:27 am -
1 stop17h 28m
Wed 11/187:05 am -
2 stops33h 16m
Deal found 9/28![United Airlines logo]()
$724
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/232:25 pm -
2 stops20h 25m
Thu 4/16:05 am -
2 stops18h 49m
Deal found 10/1![Delta logo]()
$765
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/206:00 am -
2 stops20h 55m
Fri 1/221:15 pm -
2 stops33h 39m
Deal found 9/28![United Airlines logo]()
$733
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/135:34 pm -
1 stop11h 46m
Sun 12/2010:25 am -
1 stop19h 29m
Deal found 9/29![Delta logo]()
$777
This Turkish Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/211:15 pm -
2 stops42h 35m
Thu 11/2611:15 am -
2 stops35h 48m
Deal found 9/26![Turkish Airlines logo]()
$965
This Air Canada deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:19 pm -
2 stops33h 01m
Wed 11/1110:45 am -
3 stops19h 14m
Deal found 9/30![Multiple Airlines logo]()
$969
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:49 am -
2 stops20h 41m
Wed 11/412:40 pm -
2 stops36h 21m
Deal found 9/30![United Airlines logo]()
$741
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/203:57 pm -
2 stops15h 28m
Mon 11/161:20 pm -
1 stop16h 32m
Deal found 9/30![American Airlines logo]()
$1,018
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1310:56 am -
1 stop16h 39m
Fri 11/201:30 pm -
1 stop14h 42m
Deal found 9/29![Delta logo]()
$777
This KLM deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/135:19 pm -
1 stop12h 56m
Fri 11/2012:20 pm -
2 stops17h 39m
Deal found 9/29![KLM logo]()
$955
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/96:00 am -
1 stop19h 30m
Thu 3/2511:20 am -
2 stops32h 58m
Deal found 9/30![United Airlines logo]()
$760
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/2412:52 pm -
2 stops27h 18m
Thu 4/110:15 am -
1 stop31h 55m
Deal found 10/1![Delta logo]()
$800
This Air Canada deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2210:38 am -
3 stops19h 52m
Fri 11/61:15 pm -
2 stops33h 56m
Deal found 9/27![Multiple Airlines logo]()
$1,095
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/122:52 pm -
1 stop11h 38m
Thu 11/1911:15 am -
2 stops39h 47m
Deal found 9/28![United Airlines logo]()
$761
This KLM deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1410:52 am -
1 stop17h 58m
Thu 10/229:45 am -
1 stop19h 12m
Deal found 9/28![KLM logo]()
$1,029
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/115:25 pm -
2 stops17h 45m
Fri 3/192:15 pm -
1 stop26h 55m
Deal found 9/29![Delta logo]()
$813
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/176:00 am -
1 stop19h 55m
Sun 2/281:15 pm -
2 stops37h 56m
Deal found 9/28![United Airlines logo]()
$761
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/301:00 pm -
1 stop15h 35m
Sun 11/86:10 am -
2 stops21h 02m
Deal found 10/1![Delta logo]()
$826
Last-minute flights from South Carolina to ItalyDiscover last-minute flight deals from South Carolina to Italy. Data last updated October 2, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Italy. Data last updated October 2, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/88:32 pm -
2 stops15h 18m
Tue 11/241:10 pm -
1 stop35h 19m
Deal found 10/1![American Airlines logo]()
$715
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/810:23 am -
1 stop16h 07m
Tue 11/2410:30 am -
1 stop19h 29m
Deal found 10/1![United Airlines logo]()
$718
This Expedia deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/87:00 pm -
2 stops18h 30m
Tue 11/246:10 am -
2 stops20h 14m
Deal found 10/1![KLM logo]()
$726
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1012:18 pm -
1 stop13h 27m
Tue 11/1711:15 am -
2 stops32h 41m
Deal found 9/26![United Airlines logo]()
$711
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:21 pm -
2 stops15h 34m
Wed 11/1811:00 am -
1 stop13h 12m
Deal found 9/27![American Airlines logo]()
$716
This Expedia deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:05 pm -
1 stop11h 15m
Wed 11/1810:25 am -
1 stop19h 28m
Deal found 9/27![Air France logo]()
$719
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:27 am -
1 stop17h 28m
Wed 11/187:05 am -
2 stops33h 16m
Deal found 9/28![United Airlines logo]()
$724
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/181:59 pm -
1 stop15h 21m
Thu 12/36:10 am -
2 stops21h 29m
Deal found 9/28![Delta logo]()
$726
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/227:54 pm -
1 stop30h 36m
Thu 12/39:55 am -
2 stops34h 32m
Deal found 9/28![United Airlines logo]()
$724
This Gotogate deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:20 am -
3 stops21h 45m
Tue 12/812:55 pm -
2 stops38h 04m
Deal found 9/30![Air Canada logo]()
$699
This Air France deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2312:12 pm -
1 stop16h 33m
Tue 12/812:55 pm -
1 stop15h 27m
Deal found 9/30![Air France logo]()
$711
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2311:58 am -
1 stop13h 32m
Tue 12/810:30 am -
2 stops16h 29m
Deal found 9/30![United Airlines logo]()
$713
One-way flights from South Carolina to ItalySearch for one-way flight options from South Carolina to Italy. Find affordable one-way fares based on user searches. Data last updated October 2, 2026.
Search for one-way flight options from South Carolina to Italy. Find affordable one-way fares based on user searches. Data last updated October 2, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/73:42 pm -
2 stops19h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Multiple Airlines logo]()
$300
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/203:18 pm -
3 stops44h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Multiple Airlines logo]()
$338
This Kiwi.com deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/303:27 pm -
3 stops44h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/26![Multiple Airlines logo]()
$373
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/213:42 pm -
3 stops26h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Multiple Airlines logo]()
$397
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/143:42 pm -
3 stops47h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Multiple Airlines logo]()
$410
This Expedia deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/3110:57 am -
1 stop16h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/1![British Airways logo]()
$416
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/119:18 pm -
2 stops35h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Multiple Airlines logo]()
$417
This Expedia deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/312:30 pm -
2 stops26h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/1![Lufthansa logo]()
$422
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/139:38 pm -
2 stops34h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Multiple Airlines logo]()
$432
This Cheapflightsfares deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:00 am -
2 stops22h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Aer Lingus logo]()
$434
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/249:23 am -
2 stops32h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Multiple Airlines logo]()
$440
This FlightHub deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/103:29 pm -
2 stops22h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![British Airways logo]()
$452
Find flight deals from South Carolina to Italy
Keep the following information in mind while searching for South Carolina to Italy flight deals. Data was last updated October 2, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $699 (Gotogate) |
One-way from | $300 (Kiwi.com) |
Popular in | June |
Cheapest in | February |
Average price | $877 |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 2, 2026.
Use the filters below to find and compare flights from South Carolina to Italy that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonVenice
CHS Charleston - VCE Venice Marco Polo
CHSVCE
Charleston
Tue 10/20
3:18 pm-6:00 pm
3 stops44h 42m
Venice Marco Polo
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$338
CharlestonRome
CHS Charleston - FCO Rome Fiumicino
CHSFCO
Charleston
Mon 11/30
3:27 pm-3:40 pm
2 stops42h 13m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$397
CharlestonMilan
CHS Charleston - MXP Milan Malpensa
CHSMXP
Charleston
Sat 11/14
3:42 pm-9:15 pm
3 stops47h 33m
Milan Malpensa
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$410
CharlestonVenice
CHS Charleston - VCE Venice Marco Polo
CHSVCE
Charleston
Wed 3/31
10:57 am-9:55 am
1 stop16h 58m
Venice Marco Polo
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$416
CharlestonMilan
CHS Charleston - MXP Milan Malpensa
CHSMXP
Charleston
Wed 11/11
9:18 pm-2:30 pm
2 stops35h 12m
Milan Malpensa
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$417
CharlestonVenice
CHS Charleston - VCE Venice Marco Polo
CHSVCE
Charleston
Wed 3/31
2:30 pm-10:30 pm
2 stops26h 00m
Venice Marco Polo
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$422
CharlestonMilan
CHS Charleston - MXP Milan Malpensa
CHSMXP
Charleston
Tue 11/10
3:29 pm-7:45 pm
2 stops22h 16m
Milan Malpensa
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$452
CharlestonMilan
CHS Charleston - MXP Milan Malpensa
CHSMXP
Charleston
Wed 11/11
10:55 am-10:05 am
1 stop17h 10m
Milan Malpensa
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$458
CharlestonMilan
CHS Charleston - MXP Milan Malpensa
CHSMXP
Charleston
Wed 10/28
2:35 pm-10:05 am
1 stop14h 30m
Milan Malpensa
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$458
CharlestonMilan
CHS Charleston - MXP Milan Malpensa
CHSMXP
Charleston
Wed 10/28
2:03 pm-11:20 am
2 stops16h 17m
Milan Malpensa
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$461
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Italy
Have a flexible travel schedule? Discover the best time to fly to Italy from South Carolina with our price prediction graph.
GSP-MXP
CHS-FCO
CHS-MXP
CAE-FCO
MYR-FCO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Italy
USSC-IT0
GSP-MXP
CHS-FCO
CHS-MXP
CAE-FCO
What is the cheapest month to book a flight from South Carolina to Italy?
Currently, February is the cheapest month in which you can book a flight from South Carolina to Italy (average of $527). Flying from South Carolina to Italy in June is currently the most expensive (average of $1,523). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from South Carolina to Italy?
The price you pay for your flight from South Carolina to Italy may vary depending on when you book. For the best chance of a lower fare, look to book 46 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for South Carolina to Italy
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Italy by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Italy by cabin class
Find flights from South Carolina to Italy, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Carolina and Italy flights
Browse other South Carolina and Italy flight options. Last updated on October 2, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Italy
Find the right flight back to South Carolina after your stay in Italy
South Carolina to Italy flights
Consider these flights traveling from South Carolina to Italy.
Fly to Italy regions
Consider these flights traveling to Italy regions.
Top 5 airlines flying from South Carolina to Italy
Discover the top 5 airlines that operate flights from South Carolina to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$497 | Average$1,362 | FlexibilityNo cancel fee | On-time76% | |
| Cheapest$503 | Average$1,269 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$609 | Average$1,175 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$616 | Average$1,204 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$759 | Average$1,300 | FlexibilityNo cancel fee | On-time71% |