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Italy

$269+ Cheap flights from South Carolina to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/17. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — NAP
Aug 19 — Aug 261
Wed 8/19
Wed 8/26
1 adult, Economy
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Cheap flight deals from South Carolina to Italy

Cheapest flights from South Carolina to Italy
Explore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 20, 2026.

This Justfly.com deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:45 am
CLT
-
MXP
2 stops21h 35m
Multiple Airlines
Tue 11/33:05 pm
MXP
-
CLT
2 stops55h 50m
Multiple Airlines
Deal found 7/15$606
This FlightHub deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/159:20 am
CLT
-
MXP
1 stop19h 00m
Multiple Airlines
Fri 10/2312:20 pm
MXP
-
CLT
1 stop32h 37m
Multiple Airlines
Deal found 7/15$607
This United Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:00 am
CLT
-
MXP
1 stop18h 30m
United Airlines
Fri 10/2312:20 pm
MXP
-
CLT
2 stops32h 00m
United Airlines
Deal found 7/15$611
This FlightHub deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/133:40 pm
CLT
-
MXP
2 stops36h 40m
Air Canada
Wed 10/2112:20 pm
MXP
-
CLT
2 stops38h 55m
Air Canada
Deal found 7/15$615
This Expedia deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:40 pm
CLT
-
MXP
1 stop16h 00m
Multiple Airlines
Tue 11/37:20 pm
MXP
-
CLT
2 stops51h 35m
Multiple Airlines
Deal found 7/15$622
This United Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1711:00 am
CLT
-
MXP
1 stop14h 30m
United Airlines
Tue 11/312:55 pm
MXP
-
CLT
2 stops31h 14m
United Airlines
Deal found 7/15$626
This FlightHub deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1310:25 am
CLT
-
MXP
2 stops17h 55m
Multiple Airlines
Wed 10/216:20 am
MXP
-
CLT
1 stop16h 25m
Multiple Airlines
Deal found 7/15$628
This United Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/133:59 pm
CLT
-
MXP
1 stop33h 31m
United Airlines
Wed 10/219:45 am
MXP
-
CLT
1 stop12h 50m
United Airlines
Deal found 7/15$631
This Cheapflightsfares deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:40 pm
CLT
-
LIN
1 stop12h 20m
Lufthansa
Wed 10/219:50 am
LIN
-
CLT
1 stop12h 55m
Lufthansa
Deal found 7/15$643
This Cheapflightsfares deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:50 pm
CLT
-
LIN
1 stop18h 00m
Lufthansa
Tue 11/39:45 am
LIN
-
CLT
1 stop13h 10m
Lufthansa
Deal found 7/15$657
This oojo deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:40 pm
CLT
-
LIN
1 stop17h 05m
Lufthansa
Tue 11/39:45 am
LIN
-
CLT
1 stop13h 10m
Lufthansa
Deal found 7/15$660
This Kiwi.com deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:33 pm
CLT
-
FCO
1 stop14h 57m
Multiple Airlines
Thu 10/227:05 pm
FCO
-
CLT
1 stop30h 11m
Multiple Airlines
Deal found 7/16$663

Find flight deals from South Carolina to Italy

Keep the following information in mind while searching for South Carolina to Italy flight deals. Data was last updated July 20, 2026.

Most accurate provider

Ovago
3 stars

Most trusted provider

Ovago
3 stars

Round-trip from

$606
(Justfly.com)

One-way from

$269
(KAYAK)

Popular in

July

Cheapest in

January

Average price

$2,686
Provider with most accurate pricing for Myrtle Beach Intl-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Rome (ROM) flights.
Search Deals
From South Carolina to Italy
Search Deals
One-way flight from South Carolina to Italy
Search Deals
Highest demand for flights based on searches. 34% potential increase in price ($684 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 12% potential price decrease ($140 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 20, 2026.
Use the filters below to find and compare flights from South Carolina to Italy that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteMilan

CLT - MXP

CLTMXP

Charlotte Douglas

Wed 12/2

11:05 am-7:30 am

1 stop14h 25m

Milan Malpensa

Fri 12/4

9:45 am-6:48 pm

1 stop15h 03m

$726

CharlotteMilan

CLT - LIN

CLTLIN

Charlotte Douglas

Wed 12/2

11:05 am-12:20 pm

2 stops19h 15m

Milan Linate

Fri 12/4

6:25 am-6:48 pm

2 stops18h 23m

$740

CharlotteFlorence

CLT - FLR

CLTFLR

Charlotte Douglas

Tue 8/18

1:02 pm-11:35 am

2 stops16h 33m

Florence Peretola

Tue 8/25

7:05 am-4:00 pm

1 stop14h 55m

$765

CharlotteVenice

CLT - VCE

CLTVCE

Charlotte Douglas

Tue 8/11

11:50 am-11:20 am

2 stops17h 30m

Venice Marco Polo

Thu 8/20

1:20 pm-10:58 pm

1 stop15h 38m

$777

CharlotteMilan

CLT - MXP

CLTMXP

Charlotte Douglas

Wed 12/16

8:55 am-4:40 pm

2 stops25h 45m

Milan Malpensa

Tue 1/12

12:55 pm-1:50 pm

2 stops30h 55m

$784

CharlotteMilan

CLT - LIN

CLTLIN

Charlotte Douglas

Fri 11/13

10:25 am-8:45 am

2 stops16h 20m

Milan Linate

Fri 11/27

10:55 am-9:50 pm

2 stops16h 55m

$787

CharlestonRome

CHS - FCO

CHSFCO

Charleston

Mon 11/16

11:26 am-7:55 am

1 stop14h 29m

Rome Fiumicino

Thu 11/19

7:05 am-6:06 pm

2 stops17h 01m

$787

GreenvilleRome

GSP - FCO

GSPFCO

Greenville

Sun 11/15

10:21 am-8:30 am

1 stop16h 09m

Rome Fiumicino

Thu 11/19

9:55 am-10:46 pm

2 stops18h 51m

$787

CharlotteFlorence

CLT - FLR

CLTFLR

Charlotte Douglas

Mon 12/7

1:05 pm-1:40 pm

2 stops18h 35m

Florence Peretola

Wed 12/9

2:20 pm-9:06 pm

2 stops36h 46m

$792

CharlotteMilan

CLT - LIN

CLTLIN

Charlotte Douglas

Mon 11/2

5:00 pm-1:55 pm

2 stops14h 55m

Milan Linate

Fri 11/13

6:30 am-6:16 pm

2 stops17h 46m

$804

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/18

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from South Carolina to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Italy

What is the cheapest month to book a flight from South Carolina to Italy?

Currently, February is the cheapest month in which you can book a flight from South Carolina to Italy (average of $591). Flying from South Carolina to Italy in June is currently the most expensive (average of $1,506). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How far ahead should I book a flight from South Carolina to Italy?

The price you pay for your flight from South Carolina to Italy may vary depending on when you book. For the best chance of a lower fare, look to book 44 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Italy?

    For as low as $820, United Airlines can have you in Italy from South Carolina in 14h 01m. The distance from South Carolina to Italy is about 4548 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from South Carolina to Italy that include hotel bookings?

    Yes. In addition to deals on South Carolina to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Italy.

  • Can I find deals for business class flights from South Carolina to Italy?

    Yes. Cheapflights offers flight deals from South Carolina to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Italy?

    Currently, February is the cheapest month in which you can book a flight from South Carolina to Italy (average of $591). Flying from South Carolina to Italy in June is currently the most expensive (average of $1,506). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Italy

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from South Carolina to Italy

Discover the top 6 airlines that operate flights from South Carolina to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 20, 2026.
AirlineCheapestAverageFlexibilityOn-time
LufthansaCheapest$497Average$1,362FlexibilityNo cancel feeOn-time76%
DeltaCheapest$503Average$1,249FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$575Average$1,168FlexibilityNo cancel feeOn-time69%
British AirwaysCheapest$609Average$998FlexibilityNo cancel feeOn-time70%
KLMCheapest$625Average$945FlexibilityNo cancel feeOn-time75%
American AirlinesCheapest$769Average$1,322FlexibilityNo cancel feeOn-time71%

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