$330+ Cheap flights from South Carolina to Italy
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/22. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — NAP
Dec 9 — Dec 161
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from South Carolina to ItalyExplore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 9, 2026.
Explore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 9, 2026.
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:30 am -
1 stop16h 05m
Tue 11/241:30 pm -
1 stop15h 24m
Deal found 11/4![Delta logo]()
$686
This Delta deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1511:53 am -
1 stop14h 22m
Tue 11/2410:25 am -
1 stop19h 28m
Deal found 11/7![Delta logo]()
$686
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/303:47 pm -
1 stop13h 33m
Fri 12/1810:00 am -
1 stop14h 30m
Deal found 11/4![Delta logo]()
$686
This Air France deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:30 am -
2 stops15h 15m
Tue 11/241:30 pm -
1 stop15h 24m
Deal found 11/4![Multiple Airlines logo]()
$691
This Air France deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1511:53 am -
1 stop14h 22m
Tue 11/241:30 pm -
1 stop25h 51m
Deal found 11/6![Multiple Airlines logo]()
$692
This KLM deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1511:53 am -
1 stop17h 27m
Tue 11/246:10 am -
2 stops17h 00m
Deal found 11/6![KLM logo]()
$708
This FlightHub deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/82:04 pm -
2 stops20h 26m
Tue 12/151:05 pm -
2 stops37h 54m
Deal found 11/4![Multiple Airlines logo]()
$709
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/42:57 pm -
1 stop11h 33m
Fri 12/111:15 pm -
2 stops40h 44m
Deal found 11/6![United Airlines logo]()
$711
This Air Canada deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:00 am -
2 stops20h 55m
Fri 12/111:15 pm -
2 stops31h 05m
Deal found 11/6![Multiple Airlines logo]()
$714
This Air Canada deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/256:39 pm -
2 stops56h 16m
Fri 1/221:15 pm -
2 stops27h 53m
Deal found 11/5![Air Canada logo]()
$715
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/42:57 pm -
1 stop11h 33m
Tue 12/811:15 am -
2 stops40h 06m
Deal found 11/4![United Airlines logo]()
$716
This Air Canada deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:00 am -
2 stops19h 55m
Tue 12/811:15 am -
2 stops40h 06m
Deal found 11/4![Air Canada logo]()
$719
Best flights from South Carolina to ItalyDiscover carefully curated flight deals from South Carolina to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 9, 2026.
Discover carefully curated flight deals from South Carolina to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 9, 2026.
This Delta deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1511:53 am -
1 stop14h 22m
Tue 11/2410:25 am -
1 stop19h 28m
Deal found 11/7![Delta logo]()
$686
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:30 am -
1 stop21h 15m
Tue 11/241:10 pm -
1 stop16h 13m
Deal found 11/4![American Airlines logo]()
$686
This KLM deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1511:53 am -
1 stop17h 27m
Tue 11/246:10 am -
2 stops17h 00m
Deal found 11/6![KLM logo]()
$708
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/110:23 am -
1 stop15h 07m
Thu 12/109:45 am -
1 stop20h 14m
Deal found 11/4![United Airlines logo]()
$728
This Gotogate deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:00 am -
3 stops21h 05m
Wed 12/96:55 am -
2 stops20h 26m
Deal found 11/9![Multiple Airlines logo]()
$737
This FlightHub deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/12:25 pm -
2 stops39h 05m
Sun 5/97:55 pm -
2 stops33h 00m
Deal found 11/8![Scandinavian Airlines logo]()
$795
This Finnair deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/232:09 pm -
2 stops22h 06m
Mon 11/307:00 pm -
2 stops33h 03m
Deal found 11/8![Finnair logo]()
$817
This Air Canada deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/202:42 pm -
3 stops37h 23m
Sun 1/241:05 pm -
2 stops31h 01m
Deal found 11/7![Air Canada logo]()
$822
This Expedia deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/610:54 am -
1 stop14h 11m
Wed 4/282:15 pm -
1 stop14h 21m
Deal found 11/4![British Airways logo]()
$922
This Expedia deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/1112:25 pm -
2 stops18h 50m
Sat 1/1611:00 am -
1 stop14h 24m
Deal found 11/9![Lufthansa logo]()
$1,100
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/303:47 pm -
1 stop13h 33m
Fri 12/1810:00 am -
1 stop14h 30m
Deal found 11/5![Delta logo]()
$686
This Air France deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/226:05 pm -
2 stops46h 45m
Thu 11/267:00 am -
2 stops21h 47m
Deal found 11/6![Air France logo]()
$1,437
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:20 am -
1 stop19h 25m
Fri 12/1810:30 am -
1 stop18h 05m
Deal found 11/6![United Airlines logo]()
$736
This KLM deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1111:53 am -
2 stops14h 52m
Tue 12/1510:25 am -
1 stop19h 26m
Deal found 11/9![Multiple Airlines logo]()
$741
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/259:00 am -
1 stop17h 45m
Fri 1/221:30 pm -
1 stop15h 23m
Deal found 11/5![Delta logo]()
$733
This Scandinavian Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Scandinavian Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/164:30 pm -
2 stops20h 40m
Sun 4/259:20 am -
2 stops19h 35m
Deal found 11/9![Scandinavian Airlines logo]()
$817
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/146:00 am -
2 stops26h 05m
Thu 2/186:30 am -
2 stops21h 21m
Deal found 11/4![United Airlines logo]()
$755
This FlightHub deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/45:34 pm -
2 stops58h 31m
Mon 12/145:15 pm -
2 stops36h 25m
Deal found 11/7![Multiple Airlines logo]()
$760
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/115:34 pm -
2 stops57h 21m
Mon 12/2111:00 am -
1 stop14h 02m
Deal found 11/7![United Airlines logo]()
$760
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/222:50 pm -
1 stop14h 30m
Mon 3/2210:10 am -
2 stops28h 58m
Deal found 11/4![Delta logo]()
$779
This Finnair deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/147:10 am -
2 stops29h 05m
Mon 1/187:00 pm -
2 stops33h 10m
Deal found 11/5![Multiple Airlines logo]()
$804
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/276:34 pm -
2 stops39h 46m
Wed 3/36:30 am -
2 stops23h 29m
Deal found 11/5![United Airlines logo]()
$761
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1611:20 am -
2 stops16h 35m
Fri 3/192:15 pm -
1 stop25h 37m
Deal found 11/5![Delta logo]()
$793
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/146:51 am -
1 stop19h 39m
Wed 3/1711:20 am -
2 stops27h 35m
Deal found 11/5![United Airlines logo]()
$765
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/147:59 pm -
2 stops15h 51m
Thu 3/186:30 am -
2 stops20h 16m
Deal found 11/5![Delta logo]()
$795
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/66:00 am -
1 stop19h 45m
Sat 12/121:30 pm -
2 stops49h 47m
Deal found 11/6![United Airlines logo]()
$766
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/161:00 pm -
1 stop15h 35m
Sun 3/211:30 pm -
1 stop25h 12m
Deal found 11/5![Delta logo]()
$822
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/209:45 am -
2 stops15h 45m
Sun 1/2412:55 pm -
2 stops31h 11m
Deal found 11/7![United Airlines logo]()
$768
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/146:05 am -
2 stops25h 55m
Thu 2/187:00 am -
2 stops20h 51m
Deal found 11/5![United Airlines logo]()
$772
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/512:38 pm -
2 stops19h 47m
Sun 3/146:40 am -
2 stops19h 02m
Deal found 11/4![Delta logo]()
$855
Last-minute flights from South Carolina to ItalyDiscover last-minute flight deals from South Carolina to Italy. Data last updated November 9, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Italy. Data last updated November 9, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1511:53 am -
1 stop14h 22m
Tue 11/2410:25 am -
1 stop19h 28m
Deal found 11/7![Delta logo]()
$686
This Air France deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1511:53 am -
1 stop14h 22m
Tue 11/241:30 pm -
1 stop25h 51m
Deal found 11/6![Multiple Airlines logo]()
$692
This KLM deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1511:53 am -
1 stop17h 27m
Tue 11/246:10 am -
2 stops17h 00m
Deal found 11/6![KLM logo]()
$708
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:30 am -
1 stop16h 05m
Tue 11/241:30 pm -
1 stop15h 24m
Deal found 11/4![Delta logo]()
$686
This Air France deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:30 am -
2 stops15h 15m
Tue 11/241:30 pm -
1 stop15h 24m
Deal found 11/4![Multiple Airlines logo]()
$691
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/303:47 pm -
1 stop13h 33m
Fri 12/1810:00 am -
1 stop14h 30m
Deal found 11/4![Delta logo]()
$686
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/42:57 pm -
1 stop11h 33m
Fri 12/111:15 pm -
2 stops40h 44m
Deal found 11/6![United Airlines logo]()
$711
This Air Canada deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:00 am -
2 stops20h 55m
Fri 12/111:15 pm -
2 stops31h 05m
Deal found 11/6![Multiple Airlines logo]()
$714
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/42:57 pm -
1 stop11h 33m
Tue 12/811:15 am -
2 stops40h 06m
Deal found 11/4![United Airlines logo]()
$716
This Air Canada deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:00 am -
2 stops19h 55m
Tue 12/811:15 am -
2 stops40h 06m
Deal found 11/4![Air Canada logo]()
$719
This FlightHub deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/82:04 pm -
2 stops20h 26m
Tue 12/151:05 pm -
2 stops37h 54m
Deal found 11/4![Multiple Airlines logo]()
$709
This Air Canada deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/256:39 pm -
2 stops56h 16m
Fri 1/221:15 pm -
2 stops27h 53m
Deal found 11/5![Air Canada logo]()
$715
One-way flights from South Carolina to ItalySearch for one-way flight options from South Carolina to Italy. Find affordable one-way fares based on user searches. Data last updated November 9, 2026.
Search for one-way flight options from South Carolina to Italy. Find affordable one-way fares based on user searches. Data last updated November 9, 2026.
This oojo deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/229:08 am -
1 stop17h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Lufthansa logo]()
$330
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2212:52 pm -
2 stops15h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Delta logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/123:07 pm -
2 stops49h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Multiple Airlines logo]()
$351
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/193:07 pm -
2 stops49h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/6![Multiple Airlines logo]()
$384
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/262:13 pm -
3 stops27h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Multiple Airlines logo]()
$385
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/188:32 pm -
2 stops33h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/8![Multiple Airlines logo]()
$418
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/49:47 pm -
3 stops43h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Multiple Airlines logo]()
$433
This Cheapflightsfares deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:00 am -
2 stops22h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Aer Lingus logo]()
$439
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/173:00 pm -
2 stops46h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Multiple Airlines logo]()
$478
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/92:30 pm -
3 stops45h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/6![Multiple Airlines logo]()
$509
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/72:51 pm -
3 stops41h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/6![Multiple Airlines logo]()
$511
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/53:00 pm -
2 stops45h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Multiple Airlines logo]()
$513
Find flight deals from South Carolina to Italy
Keep the following information in mind while searching for South Carolina to Italy flight deals. Data was last updated November 9, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $683 (Justfly.com) |
One-way from | $330 (oojo) |
Popular in | June |
Cheapest in | January |
Average price | $1,255 |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 9, 2026.
Use the filters below to find and compare flights from South Carolina to Italy that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonRome
CHS Charleston - FCO Rome Fiumicino
CHSFCO
Charleston
Mon 3/22
9:08 am-7:45 am
1 stop17h 37m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$331
CharlestonRome
CHS Charleston - FCO Rome Fiumicino
CHSFCO
Charleston
Mon 3/22
12:52 pm-9:20 am
2 stops15h 28m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$349
CharlestonFlorence
CHS Charleston - FLR Florence Peretola
CHSFLR
Charleston
Tue 1/12
3:07 pm-11:05 pm
2 stops49h 58m
Florence Peretola
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$351
CharlestonFlorence
CHS Charleston - FLR Florence Peretola
CHSFLR
Charleston
Tue 1/19
3:07 pm-11:05 pm
2 stops49h 58m
Florence Peretola
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$384
GreenvilleRome
GSP Greenville - FCO Rome Fiumicino
GSPFCO
Greenville
Mon 1/18
8:32 pm-12:15 pm
2 stops33h 43m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$418
CharlestonVenice
CHS Charleston - VCE Venice Marco Polo
CHSVCE
Charleston
Fri 12/4
9:47 pm-11:45 pm
3 stops43h 58m
Venice Marco Polo
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$433
CharlestonVenice
CHS Charleston - VCE Venice Marco Polo
CHSVCE
Charleston
Tue 11/17
3:00 pm-7:45 pm
2 stops46h 45m
Venice Marco Polo
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$478
CharlestonMilan
CHS Charleston - MXP Milan Malpensa
CHSMXP
Charleston
Tue 1/5
3:00 pm-6:05 pm
2 stops45h 05m
Milan Malpensa
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$513
Quickest round-trip
GreenvilleRome
GSP Greenville - FCO Rome Fiumicino
GSPFCO
Greenville
Mon 1/18
2:57 pm-8:30 am
1 stop11h 33m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$524
Myrtle BeachRome
MYR Myrtle Beach Intl - FCO Rome Fiumicino
MYRFCO
Myrtle Beach Intl
Sat 1/9
6:29 pm-8:55 am
2 stops32h 26m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$538
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Italy
Have a flexible travel schedule? Discover the best time to fly to Italy from South Carolina with our price prediction graph.
CAE-FCO
CHS-MXP
CHS-FLR
GSP-MXP
MYR-FCO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Italy
USSC-IT0
CAE-FCO
CHS-MXP
CHS-FLR
GSP-MXP
What is the cheapest month to book a flight from South Carolina to Italy?
Currently, February is the cheapest month in which you can book a flight from South Carolina to Italy (average of $560). Flying from South Carolina to Italy in June is currently the most expensive (average of $1,545). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from South Carolina to Italy?
The price you pay for your flight from South Carolina to Italy may vary depending on when you book. For the best chance of a lower fare, look to book 48 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for South Carolina to Italy
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Italy by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Italy by cabin class
Find flights from South Carolina to Italy, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Carolina and Italy flights
Browse other South Carolina and Italy flight options. Last updated on November 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Italy
Find the right flight back to South Carolina after your stay in Italy
South Carolina to Italy flights
Consider these flights traveling from South Carolina to Italy.
Fly to Italy regions
Consider these flights traveling to Italy regions.
Top 5 airlines flying from South Carolina to Italy
Discover the top 5 airlines that operate flights from South Carolina to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$497 | Average$1,353 | FlexibilityNo cancel fee | On-time76% | |
| Cheapest$503 | Average$1,256 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$609 | Average$1,175 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$616 | Average$1,234 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$759 | Average$1,306 | FlexibilityNo cancel fee | On-time71% |