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$305+ Cheap flights from South Carolina to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/17. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — NAP
juni 27 — juli 41
lør. 6/27
lør. 7/4
1 adult, Economy
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Cheap flight deals from South Carolina to Italy

Cheapest flights from South Carolina to Italy
Explore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on maj 28, 2026.

This SWISS deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SWISS is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
søn. 11/296:50 pm
CLT
-
FLR
2 stops41h 15m
SWISS
fre. 12/116:55 pm
FLR
-
CLT
2 stops28h 00m
SWISS
Deal found 5/24$623
This British Airways deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
fre. 12/41:55 pm
CLT
-
VCE
2 stops15h 15m
Multiple Airlines
fre. 12/116:20 am
VCE
-
CLT
1 stop15h 50m
Multiple Airlines
Deal found 5/26$669
This KAYAK deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ons. 10/281:00 pm
CLT
-
LIN
2 stops17h 05m
Multiple Airlines
ons. 11/411:25 am
LIN
-
CLT
1 stop32h 55m
Multiple Airlines
Deal found 5/25$675
This Justfly.com deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
søn. 10/255:00 pm
CLT
-
MXP
1 stop35h 05m
Multiple Airlines
tor. 11/59:50 am
MXP
-
CLT
1 stop13h 05m
Multiple Airlines
Deal found 5/25$704
This Cheapflightsfares deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
tir. 12/16:50 pm
CLT
-
VCE
1 stop11h 55m
Lufthansa
tir. 12/88:00 am
VCE
-
CLT
1 stop14h 55m
Lufthansa
Deal found 5/25$704
This KAYAK deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ons. 12/21:00 pm
CLT
-
MXP
1 stop12h 30m
Brussels Airlines
ons. 12/91:05 pm
MXP
-
CLT
2 stops34h 02m
Brussels Airlines
Deal found 5/25$706
This American Airlines deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
tir. 10/2711:30 pm
CLT
-
VCE
1 stop16h 55m
American Airlines
ons. 11/48:35 pm
VCE
-
CLT
1 stop25h 30m
American Airlines
Deal found 5/26$714
This Cheapflightsfares deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
tir. 10/277:50 pm
CLT
-
VCE
2 stops17h 35m
SWISS
ons. 11/47:15 pm
VCE
-
CLT
2 stops27h 40m
SWISS
Deal found 5/26$715
This Cheapflightsfares deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
søn. 10/257:50 pm
CLT
-
MXP
2 stops17h 40m
SWISS
tor. 11/56:45 am
MXP
-
CLT
2 stops20h 38m
SWISS
Deal found 5/25$718
This American Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ons. 12/210:30 pm
CLT
-
MXP
1 stop15h 30m
American Airlines
ons. 12/910:20 am
MXP
-
CLT
1 stop17h 06m
American Airlines
Deal found 5/25$719
This Cheapflightsfares deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
søn. 10/257:50 pm
CLT
-
LIN
1 stop18h 00m
Lufthansa
tor. 11/59:45 am
LIN
-
CLT
1 stop13h 10m
Lufthansa
Deal found 5/27$720
This Booking.com deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ons. 12/25:00 pm
CLT
-
MXP
2 stops15h 15m
Air Canada
ons. 12/91:05 pm
MXP
-
CLT
2 stops34h 02m
Air Canada
Deal found 5/25$720

Find flight deals from South Carolina to Italy

Keep the following information in mind while searching for South Carolina to Italy flight deals. Data was last updated maj 28, 2026.

Most accurate provider

Ovago
3 stars

Most trusted provider

Ovago
3 stars

Round-trip from

$675
(KAYAK)

One-way from

$305
(Kiwi.com)

Popular in

June

Cheapest in

January

Average price

$1,473
Provider with most accurate pricing for Myrtle Beach Intl-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Rome (ROM) flights.
Search Deals
From South Carolina to Italy
Search Deals
One-way flight from South Carolina to Italy
Search Deals
Highest demand for flights based on searches. 29% potential increase in price ($474 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($90 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated maj 28, 2026.
Use the filters below to find and compare flights from South Carolina to Italy that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteFlorence

CLT - FLR

CLTFLR

Charlotte Douglas

søn. 8/16

1:02 pm-11:50 am

2 stops16h 48m

Florence Peretola

tor. 8/27

12:25 pm-11:54 pm

2 stops17h 29m

$727

CharlotteVenice

CLT - VCE

CLTVCE

Charlotte Douglas

ons. 8/12

3:00 pm-7:55 am

1 stop10h 55m

Venice Marco Polo

ons. 8/19

12:20 pm-2:05 pm

2 stops31h 45m

$759

CharlotteMilan

CLT - MXP

CLTMXP

Charlotte Douglas

tir. 10/27

5:28 pm-1:05 pm

1 stop14h 37m

Milan Malpensa

tir. 11/3

1:05 pm-3:53 pm

2 stops32h 48m

$774

CharlotteFlorence

CLT - FLR

CLTFLR

Charlotte Douglas

tir. 8/18

6:40 pm-6:55 pm

2 stops18h 15m

Florence Peretola

tir. 8/25

9:55 am-9:46 pm

2 stops17h 51m

$792

CharlotteFlorence

CLT - FLR

CLTFLR

Charlotte Douglas

tir. 10/20

1:00 pm-11:35 am

2 stops16h 35m

Florence Peretola

ons. 10/28

12:10 pm-8:25 am

2 stops25h 15m

$796

CharlotteFlorence

CLT - FLR

CLTFLR

Charlotte Douglas

ons. 8/19

1:02 pm-11:35 am

2 stops16h 33m

Florence Peretola

ons. 8/26

7:05 am-7:19 pm

2 stops18h 14m

$805

CharlotteMilan

CLT - MXP

CLTMXP

Charlotte Douglas

søn. 8/16

6:05 am-9:25 am

1 stop21h 20m

Milan Malpensa

lør. 8/29

11:35 am-8:34 pm

1 stop14h 59m

$815

CharlotteMilan

CLT - LIN

CLTLIN

Charlotte Douglas

tir. 8/18

6:40 pm-5:45 pm

1 stop17h 05m

Milan Linate

lør. 8/29

10:40 am-6:56 pm

2 stops14h 16m

$824

CharlotteVenice

CLT - VCE

CLTVCE

Charlotte Douglas

lør. 10/31

7:47 pm-4:15 pm

2 stops39h 28m

Venice Marco Polo

tir. 11/17

8:00 am-4:55 pm

1 stop14h 55m

$826

CharlotteVenice

CLT - VCE

CLTVCE

Charlotte Douglas

søn. 8/16

8:05 am-9:05 am

2 stops19h 00m

Venice Marco Polo

lør. 8/22

1:25 pm-4:45 pm

1 stop33h 20m

$834

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/28

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from South Carolina to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Italy

What is the cheapest month to book a flight from South Carolina to Italy?

Currently, June is the cheapest month in which you can book a flight from South Carolina to Italy (average of $147). Flying from South Carolina to Italy in July is currently the most expensive (average of $715). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How far ahead should I book a flight from South Carolina to Italy?

The price you pay for your flight from South Carolina to Italy may vary depending on when you book. For the best chance of a lower fare, look to book 39 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Italy?

    For as low as $759, United Airlines can have you in Italy from South Carolina in 10h 55m. The distance from South Carolina to Italy is about 4678 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from South Carolina to Italy that include hotel bookings?

    Yes. In addition to deals on South Carolina to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Italy.

  • Can I find deals for business class flights from South Carolina to Italy?

    Yes. Cheapflights offers flight deals from South Carolina to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Italy?

    Currently, June is the cheapest month in which you can book a flight from South Carolina to Italy (average of $147). Flying from South Carolina to Italy in July is currently the most expensive (average of $715). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Italy

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from South Carolina to Italy

Discover the top 6 airlines that operate flights from South Carolina to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated maj 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$307Average$1,014FlexibilityNo cancel feeOn-time69%
British AirwaysCheapest$468Average$985FlexibilityNo cancel feeOn-time70%
DeltaCheapest$511Average$1,215FlexibilityNo cancel feeOn-timeN/A
KLMCheapest$625Average$945FlexibilityNo cancel feeOn-time75%
American AirlinesCheapest$734Average$1,235FlexibilityNo cancel feeOn-time71%
LufthansaCheapest$745Average$1,398FlexibilityNo cancel feeOn-time76%

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