$336+ Cheap flights from South Carolina to Italy
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/22. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — FCO
Nov 12 — Nov 191
Round-trip
1 adult, Economy
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Find cheap flights from South Carolina to Italy with Cheapflights
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Cheapest flights from South Carolina to ItalyExplore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 13, 2026.
Explore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 13, 2026.
This Expedia deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/811:00 am -
1 stop16h 00m
Tue 12/151:10 pm -
1 stop16h 16m
Deal found 10/8![British Airways logo]()
$728
This United Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:27 am -
1 stop14h 28m
Fri 11/201:15 pm -
2 stops33h 56m
Deal found 10/10![United Airlines logo]()
$730
This Expedia deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/87:56 pm -
2 stops16h 04m
Tue 12/157:05 am -
2 stops22h 54m
Deal found 10/8![Lufthansa logo]()
$732
This Flysmarter deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flysmarter is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/92:00 pm -
1 stop12h 15m
Tue 11/2410:00 am -
1 stop14h 08m
Deal found 10/12![Air France logo]()
$735
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/110:23 am -
1 stop15h 07m
Thu 12/109:45 am -
1 stop20h 14m
Deal found 10/8![United Airlines logo]()
$735
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/87:54 pm -
1 stop30h 36m
Tue 11/179:55 am -
2 stops34h 22m
Deal found 10/8![United Airlines logo]()
$737
This Air Canada deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1710:37 am -
2 stops18h 18m
Wed 11/251:15 pm -
2 stops30h 52m
Deal found 10/9![Multiple Airlines logo]()
$738
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:00 am -
1 stop21h 55m
Tue 11/247:05 am -
2 stops22h 54m
Deal found 10/12![United Airlines logo]()
$739
This Delta deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/14:17 pm -
2 stops16h 38m
Thu 12/1012:55 pm -
1 stop17h 09m
Deal found 10/8![Delta logo]()
$739
This KLM deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/811:28 am -
1 stop14h 47m
Tue 11/171:30 pm -
1 stop25h 51m
Deal found 10/8![KLM logo]()
$740
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/88:32 pm -
2 stops15h 18m
Tue 11/177:30 am -
2 stops17h 17m
Deal found 10/8![American Airlines logo]()
$741
This Expedia deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:46 pm -
1 stop11h 59m
Wed 12/28:30 pm -
2 stops49h 57m
Deal found 10/11![KLM logo]()
$742
Best flights from South Carolina to ItalyDiscover carefully curated flight deals from South Carolina to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 13, 2026.
Discover carefully curated flight deals from South Carolina to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 13, 2026.
This United Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:27 am -
2 stops15h 28m
Fri 11/201:15 pm -
2 stops33h 56m
Deal found 10/10![United Airlines logo]()
$733
This FlightHub deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/23:23 pm -
2 stops15h 07m
Fri 2/56:30 am -
2 stops23h 29m
Deal found 10/9![Lufthansa logo]()
$734
This Air Canada deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1710:37 am -
2 stops18h 18m
Wed 11/251:15 pm -
2 stops30h 52m
Deal found 10/12![Multiple Airlines logo]()
$738
This Delta deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/14:17 pm -
2 stops16h 38m
Thu 12/1012:55 pm -
1 stop17h 09m
Deal found 10/8![Delta logo]()
$739
This American Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/12:10 pm -
2 stops15h 20m
Thu 12/1010:25 am -
2 stops17h 36m
Deal found 10/9![American Airlines logo]()
$740
This Air France deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/3012:12 pm -
1 stop17h 08m
Fri 12/1810:25 am -
1 stop17h 57m
Deal found 10/8![Air France logo]()
$750
This Air Canada deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/116:00 am -
3 stops21h 40m
Tue 2/166:30 am -
3 stops22h 49m
Deal found 10/13![Air Canada logo]()
$819
This KLM deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/46:00 am -
1 stop20h 10m
Wed 4/2110:45 am -
2 stops19h 11m
Deal found 10/9![KLM logo]()
$835
This Scandinavian Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Scandinavian Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/16:00 am -
3 stops22h 35m
Sat 4/109:20 am -
2 stops20h 36m
Deal found 10/11![Scandinavian Airlines logo]()
$1,037
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/206:00 am -
2 stops20h 55m
Fri 1/221:15 pm -
2 stops37h 48m
Deal found 10/12![United Airlines logo]()
$733
This Delta deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/81:59 pm -
1 stop12h 16m
Tue 11/1711:45 am -
1 stop15h 58m
Deal found 10/8![Delta logo]()
$740
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/305:52 pm -
2 stops15h 03m
Fri 12/181:10 pm -
1 stop27h 28m
Deal found 10/8![American Airlines logo]()
$753
This Finnair deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/152:10 pm -
2 stops25h 45m
Mon 3/16:40 pm -
2 stops34h 00m
Deal found 10/9![Multiple Airlines logo]()
$753
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/110:23 am -
1 stop15h 07m
Thu 12/109:45 am -
1 stop20h 14m
Deal found 10/8![United Airlines logo]()
$735
This Delta deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/308:11 am -
1 stop18h 04m
Fri 12/1810:00 am -
2 stops18h 22m
Deal found 10/10![Delta logo]()
$755
This KLM deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/1410:14 am -
1 stop18h 31m
Sun 2/2112:55 pm -
1 stop14h 26m
Deal found 10/8![KLM logo]()
$837
This United deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/910:23 am -
2 stops15h 07m
Mon 11/1612:55 pm -
2 stops34h 44m
Deal found 10/10![Multiple Airlines logo]()
$769
This Air Canada deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2310:42 am -
2 stops17h 23m
Mon 11/3012:55 pm -
2 stops40h 45m
Deal found 10/9![Air Canada logo]()
$875
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/146:00 am -
2 stops46h 05m
Fri 2/1912:55 pm -
2 stops40h 16m
Deal found 10/8![United Airlines logo]()
$736
This Delta deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/912:24 pm -
1 stop15h 26m
Mon 11/1612:00 pm -
1 stop14h 24m
Deal found 10/10![Delta logo]()
$785
This KLM deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/56:00 am -
1 stop20h 10m
Mon 4/198:15 am -
2 stops18h 27m
Deal found 10/9![KLM logo]()
$885
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/17:51 pm -
2 stops30h 04m
Fri 2/51:15 pm -
2 stops35h 53m
Deal found 10/12![United Airlines logo]()
$739
This Finnair deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/67:00 am -
2 stops28h 55m
Sat 12/126:40 pm -
2 stops33h 44m
Deal found 10/9![Multiple Airlines logo]()
$819
This Delta deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2612:00 pm -
1 stop17h 20m
Thu 12/31:30 pm -
1 stop14h 09m
Deal found 10/12![Delta logo]()
$800
This United Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/186:29 pm -
1 stop31h 26m
Fri 1/221:15 pm -
2 stops51h 31m
Deal found 10/9![United Airlines logo]()
$745
This Turkish Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/39:40 am -
2 stops50h 35m
Wed 12/211:15 am -
2 stops30h 38m
Deal found 10/12![Multiple Airlines logo]()
$840
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/13:23 pm -
2 stops16h 27m
Fri 2/56:30 am -
2 stops23h 29m
Deal found 10/12![United Airlines logo]()
$745
This Delta deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/301:00 pm -
2 stops16h 25m
Wed 1/136:40 am -
2 stops20h 25m
Deal found 10/11![Delta logo]()
$821
This KLM deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/16:00 am -
1 stop18h 45m
Sat 4/1011:40 am -
1 stop16h 06m
Deal found 10/11![KLM logo]()
$1,035
This United Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1710:37 am -
1 stop15h 08m
Wed 11/257:05 am -
2 stops18h 03m
Deal found 10/9![United Airlines logo]()
$747
Last-minute flights from South Carolina to ItalyDiscover last-minute flight deals from South Carolina to Italy. Data last updated October 13, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Italy. Data last updated October 13, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/87:54 pm -
1 stop30h 36m
Tue 11/179:55 am -
2 stops34h 22m
Deal found 10/8![United Airlines logo]()
$737
This KLM deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/811:28 am -
1 stop14h 47m
Tue 11/171:30 pm -
1 stop25h 51m
Deal found 10/8![KLM logo]()
$740
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/88:32 pm -
2 stops15h 18m
Tue 11/177:30 am -
2 stops17h 17m
Deal found 10/8![American Airlines logo]()
$741
This Flysmarter deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flysmarter is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/92:00 pm -
1 stop12h 15m
Tue 11/2410:00 am -
1 stop14h 08m
Deal found 10/12![Air France logo]()
$735
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/92:52 pm -
2 stops14h 03m
Tue 11/247:05 am -
2 stops22h 54m
Deal found 10/12![United Airlines logo]()
$739
This Cheapflightsfares deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:00 pm -
2 stops22h 10m
Tue 11/179:55 am -
2 stops15h 16m
Deal found 10/10![Lufthansa logo]()
$745
This KLM deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1012:58 pm -
1 stop13h 17m
Tue 11/1711:45 am -
1 stop14h 39m
Deal found 10/10![KLM logo]()
$750
This United Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:27 am -
1 stop14h 28m
Fri 11/201:15 pm -
2 stops33h 56m
Deal found 10/10![United Airlines logo]()
$730
This KLM deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/112:18 pm -
1 stop11h 57m
Fri 11/201:30 pm -
1 stop15h 24m
Deal found 10/10![KLM logo]()
$750
This Air Canada deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1710:37 am -
2 stops18h 18m
Wed 11/251:15 pm -
2 stops30h 52m
Deal found 10/9![Multiple Airlines logo]()
$738
This United Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1710:37 am -
1 stop15h 08m
Wed 11/257:05 am -
2 stops18h 03m
Deal found 10/9![United Airlines logo]()
$747
This Expedia deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:46 pm -
1 stop11h 59m
Wed 12/28:30 pm -
2 stops49h 57m
Deal found 10/11![KLM logo]()
$742
One-way flights from South Carolina to ItalySearch for one-way flight options from South Carolina to Italy. Find affordable one-way fares based on user searches. Data last updated October 13, 2026.
Search for one-way flight options from South Carolina to Italy. Find affordable one-way fares based on user searches. Data last updated October 13, 2026.
This FlightHub deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2211:01 am -
2 stops20h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/9![British Airways logo]()
$336
This FlightHub deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/188:00 am -
2 stops26h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/9![British Airways logo]()
$336
This oojo deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2210:23 am -
1 stop17h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/11![Lufthansa logo]()
$339
This oojo deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/182:57 pm -
1 stop11h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/9![Lufthansa logo]()
$339
This KLM deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2212:15 pm -
1 stop18h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/9![KLM logo]()
$340
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/182:57 pm -
1 stop11h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/12![United Airlines logo]()
$340
This TravelUp deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure TravelUp is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/137:42 pm -
2 stops43h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/10![Lufthansa logo]()
$363
This Air Canada deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/137:42 pm -
3 stops56h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/10![Air Canada logo]()
$366
This American Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1111:06 am -
2 stops14h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/10![American Airlines logo]()
$397
This Justfly.com deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/116:30 am -
3 stops21h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/10![Air Canada logo]()
$405
This Expedia deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/108:16 pm -
1 stop32h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/11![British Airways logo]()
$425
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/55:20 pm -
2 stops23h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/12![American Airlines logo]()
$426
Find flight deals from South Carolina to Italy
Keep the following information in mind while searching for South Carolina to Italy flight deals. Data was last updated October 13, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $728 (Expedia) |
One-way from | $336 (FlightHub) |
Popular in | July |
Cheapest in | January |
Average price | $997 |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 13, 2026.
Use the filters below to find and compare flights from South Carolina to Italy that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonRome
CHS Charleston - FCO Rome Fiumicino
CHSFCO
Charleston
Mon 3/22
11:01 am-12:55 pm
2 stops20h 54m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$336
CharlestonRome
CHS Charleston - FCO Rome Fiumicino
CHSFCO
Charleston
Mon 3/22
10:23 am-8:30 am
1 stop17h 07m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$339
Quickest round-trip
GreenvilleRome
GSP Greenville - FCO Rome Fiumicino
GSPFCO
Greenville
Mon 1/18
2:57 pm-8:30 am
1 stop11h 33m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$339
CharlestonRome
CHS Charleston - FCO Rome Fiumicino
CHSFCO
Charleston
Mon 3/22
12:15 pm-11:20 am
1 stop18h 05m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$340
CharlestonRome
CHS Charleston - FCO Rome Fiumicino
CHSFCO
Charleston
Mon 3/22
10:30 am-9:35 am
2 stops18h 05m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$340
CharlestonRome
CHS Charleston - FCO Rome Fiumicino
CHSFCO
Charleston
Mon 3/22
10:23 am-8:30 am
1 stop17h 07m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$340
GreenvilleRome
GSP Greenville - FCO Rome Fiumicino
GSPFCO
Greenville
Mon 1/18
2:57 pm-8:30 am
1 stop11h 33m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$340
GreenvilleRome
GSP Greenville - FCO Rome Fiumicino
GSPFCO
Greenville
Wed 1/20
2:57 pm-8:30 am
1 stop11h 33m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$340
GreenvilleMilan
GSP Greenville - MXP Milan Malpensa
GSPMXP
Greenville
Sat 2/13
7:42 pm-8:50 pm
2 stops43h 08m
Milan Malpensa
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$363
CharlestonRome
CHS Charleston - FCO Rome Fiumicino
CHSFCO
Charleston
Sat 4/10
8:16 pm-10:20 am
1 stop32h 04m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$425
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Italy
Have a flexible travel schedule? Discover the best time to fly to Italy from South Carolina with our price prediction graph.
MYR-FCO
CHS-FCO
CAE-FCO
CHS-FLR
CHS-MXP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Italy
USSC-IT0
MYR-FCO
CHS-FCO
CAE-FCO
CHS-FLR
What is the cheapest month to book a flight from South Carolina to Italy?
Currently, February is the cheapest month in which you can book a flight from South Carolina to Italy (average of $527). Flying from South Carolina to Italy in June is currently the most expensive (average of $1,523). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from South Carolina to Italy?
The price you pay for your flight from South Carolina to Italy may vary depending on when you book. For the best chance of a lower fare, look to book 47 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for South Carolina to Italy
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Italy by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Italy by cabin class
Find flights from South Carolina to Italy, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Carolina and Italy flights
Browse other South Carolina and Italy flight options. Last updated on October 13, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Italy
Find the right flight back to South Carolina after your stay in Italy
South Carolina to Italy flights
Consider these flights traveling from South Carolina to Italy.
Fly to Italy regions
Consider these flights traveling to Italy regions.
Top 5 airlines flying from South Carolina to Italy
Discover the top 5 airlines that operate flights from South Carolina to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$497 | Average$1,362 | FlexibilityNo cancel fee | On-time76% | |
| Cheapest$503 | Average$1,268 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$609 | Average$1,175 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$616 | Average$1,204 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$759 | Average$1,315 | FlexibilityNo cancel fee | On-time71% |