HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Italy

$272+ Cheap flights from South Carolina to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/22. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — NAP
Aug 8 — Aug 151
Sat 8/8
Sat 8/15
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from South Carolina to Italy with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from South Carolina to Italy

Cheapest flights from South Carolina to Italy
Explore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 9, 2026.

This Gotogate deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/209:20 am
CLT
-
MXP
2 stops19h 00m
Multiple Airlines
Wed 11/41:20 pm
MXP
-
CLT
1 stop33h 35m
Multiple Airlines
Deal found 7/7$567
This Air Canada deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/203:01 pm
CLT
-
MXP
2 stops13h 19m
Air Canada
Wed 11/411:20 am
MXP
-
CLT
2 stops39h 46m
Air Canada
Deal found 7/6$602
This United deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:40 pm
CLT
-
LIN
1 stop17h 05m
Multiple Airlines
Wed 11/47:35 pm
LIN
-
CLT
1 stop27h 20m
Multiple Airlines
Deal found 7/7$606
This Justfly.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/159:20 am
CLT
-
MXP
1 stop19h 00m
Multiple Airlines
Fri 10/2312:20 pm
MXP
-
CLT
1 stop32h 37m
Multiple Airlines
Deal found 7/8$607
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:00 am
CLT
-
MXP
1 stop18h 30m
United Airlines
Fri 10/2312:20 pm
MXP
-
CLT
2 stops32h 00m
United Airlines
Deal found 7/8$611
This FlightHub deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/133:40 pm
CLT
-
MXP
2 stops36h 40m
Air Canada
Wed 10/2112:20 pm
MXP
-
CLT
2 stops38h 55m
Air Canada
Deal found 7/8$615
This FlightHub deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:50 pm
CLT
-
MXP
1 stop11h 45m
Multiple Airlines
Tue 11/37:20 pm
MXP
-
CLT
2 stops51h 35m
Multiple Airlines
Deal found 7/8$616
This oojo deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:40 pm
CLT
-
LIN
1 stop12h 20m
Lufthansa
Fri 10/239:50 am
LIN
-
CLT
1 stop12h 55m
Lufthansa
Deal found 7/6$638
This Cheapflightsfares deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:40 pm
CLT
-
LIN
1 stop12h 20m
Lufthansa
Wed 10/219:50 am
LIN
-
CLT
1 stop12h 55m
Lufthansa
Deal found 7/8$643
This Cheapflightsfares deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:50 pm
CLT
-
LIN
1 stop18h 00m
Lufthansa
Tue 11/39:45 am
LIN
-
CLT
1 stop13h 10m
Lufthansa
Deal found 7/8$657
This Cheapflightsfares deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2012:30 pm
CLT
-
LIN
2 stops15h 30m
Lufthansa
Wed 11/46:55 pm
LIN
-
CLT
2 stops28h 00m
Lufthansa
Deal found 7/7$658
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/133:01 pm
CLT
-
LIN
2 stops15h 19m
United Airlines
Wed 10/216:50 am
LIN
-
CLT
2 stops18h 10m
United Airlines
Deal found 7/8$665

Find flight deals from South Carolina to Italy

Keep the following information in mind while searching for South Carolina to Italy flight deals. Data was last updated July 9, 2026.

Most accurate provider

Ovago
3 stars

Most trusted provider

Ovago
3 stars

Round-trip from

$606
(United)

One-way from

$272
(Kiwi.com)

Popular in

July

Cheapest in

January

Average price

$2,686
Provider with most accurate pricing for Myrtle Beach Intl-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Rome (ROM) flights.
Search Deals
From South Carolina to Italy
Search Deals
One-way flight from South Carolina to Italy
Search Deals
Highest demand for flights based on searches. 34% potential increase in price ($660 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 12% potential price decrease ($142 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 9, 2026.
Use the filters below to find and compare flights from South Carolina to Italy that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteVenice

CLT - VCE

CLTVCE

Charlotte Douglas

Wed 8/12

3:00 pm-7:55 am

1 stop10h 55m

Venice Marco Polo

Wed 8/19

12:20 pm-5:17 pm

2 stops34h 57m

$758

CharlestonRome

CHS - FCO

CHSFCO

Charleston

Tue 10/13

3:00 pm-8:15 am

1 stop11h 15m

Rome Fiumicino

Fri 10/23

11:30 am-3:00 pm

2 stops33h 30m

$771

CharlotteVenice

CLT - VCE

CLTVCE

Charlotte Douglas

Mon 8/3

9:33 am-11:20 am

2 stops19h 47m

Venice Marco Polo

Wed 8/19

1:20 pm-8:52 am

2 stops25h 32m

$778

CharlestonRome

CHS - FCO

CHSFCO

Charleston

Sun 11/8

9:54 am-7:45 am

1 stop15h 51m

Rome Fiumicino

Tue 11/17

9:45 am-9:19 pm

1 stop17h 34m

$790

CharlestonRome

CHS - FCO

CHSFCO

Charleston

Sun 11/15

10:19 am-8:30 am

1 stop16h 11m

Rome Fiumicino

Thu 11/19

10:30 am-11:48 pm

1 stop19h 18m

$790

CharlestonRome

CHS - FCO

CHSFCO

Charleston

Wed 10/14

3:00 pm-8:15 am

1 stop11h 15m

Rome Fiumicino

Thu 10/22

10:20 am-12:15 am

1 stop19h 55m

$792

CharlotteMilan

CLT - MXP

CLTMXP

Charlotte Douglas

Tue 10/6

11:00 am-7:30 am

1 stop14h 30m

Milan Malpensa

Fri 10/23

12:20 pm-5:18 pm

2 stops34h 58m

$810

CharlotteMilan

CLT - LIN

CLTLIN

Charlotte Douglas

Sun 8/2

5:55 pm-1:30 pm

1 stop13h 35m

Milan Linate

Tue 8/18

7:50 pm-1:15 pm

1 stop23h 25m

$812

CharlotteVenice

CLT - VCE

CLTVCE

Charlotte Douglas

Mon 8/24

10:25 am-7:55 am

1 stop15h 30m

Venice Marco Polo

Mon 8/31

9:55 am-4:45 pm

1 stop12h 50m

$818

CharlotteNaples

CLT - NAP

CLTNAP

Charlotte Douglas

Wed 8/19

7:00 am-7:00 am

1 stop18h 00m

Naples

Wed 8/26

6:00 am-8:59 pm

2 stops44h 59m

$819

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/8

Showing 1-10 of 60 resultsSorted by cheapest first
1
2
3
...
6

Best time to book a flight from South Carolina to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Italy

What is the cheapest month to book a flight from South Carolina to Italy?

Currently, September is the cheapest month in which you can book a flight from South Carolina to Italy (average of $147). Flying from South Carolina to Italy in July is currently the most expensive (average of $715). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How far ahead should I book a flight from South Carolina to Italy?

The price you pay for your flight from South Carolina to Italy may vary depending on when you book. For the best chance of a lower fare, look to book 44 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Italy?

    For as low as $758, United Airlines can have you in Italy from South Carolina in 10h 55m. The distance from South Carolina to Italy is about 4678 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from South Carolina to Italy that include hotel bookings?

    Yes. In addition to deals on South Carolina to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Italy.

  • Can I find deals for business class flights from South Carolina to Italy?

    Yes. Cheapflights offers flight deals from South Carolina to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Italy?

    Currently, September is the cheapest month in which you can book a flight from South Carolina to Italy (average of $147). Flying from South Carolina to Italy in July is currently the most expensive (average of $715). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Italy

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Heathrow flights
Newark to Heathrow flights
John F Kennedy Intl to Charles de Gaulle flights
Newark to Charles de Gaulle flights
John F Kennedy Intl to Leonardo da Vinci/Fiumicino flights
Newark to Leonardo da Vinci/Fiumicino flights
LaGuardia to Heathrow flights
Newark to Gatwick flights
Newark to Athens flights
John F Kennedy Intl to Gatwick flights
John F Kennedy Intl to Istanbul flights
John F Kennedy Intl to London City flights
Dulles Intl to Heathrow flights
Boston to Heathrow flights
John F Kennedy Intl to Barcelona-El Prat flights
Newark to Dublin flights
John F Kennedy Intl to Madrid flights
Newark to Barcelona-El Prat flights
Los Angeles to Heathrow flights
John F Kennedy Intl to Lisbon flights
Newark to Madrid flights
John F Kennedy Intl to Dublin flights
Baltimore to Heathrow flights
John F Kennedy Intl to Athens flights
John F Kennedy Intl to Orly flights
John F Kennedy Intl to Malpensa flights
LaGuardia to Gatwick flights
Los Angeles to Charles de Gaulle flights
Newark to Lisbon flights
Dallas/Fort Worth to Heathrow flights
Newark to Orly flights
O'Hare Intl to Heathrow flights
Newark to Malpensa flights
Miami to Madrid flights
San Francisco to Heathrow flights
Dulles Intl to Charles de Gaulle flights
Seattle to Heathrow flights
John F Kennedy Intl to Edinburgh flights
John F Kennedy Intl to Frederic Chopin flights
Boston to Dublin flights
Los Angeles to Leonardo da Vinci/Fiumicino flights
Newark to Stansted flights
Boston to Leonardo da Vinci/Fiumicino flights
John F Kennedy Intl to Frankfurt flights
Boston to Gatwick flights
Newark to Frankfurt flights

Top 6 airlines flying from South Carolina to Italy

Discover the top 6 airlines that operate flights from South Carolina to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 9, 2026.
AirlineCheapestAverageFlexibilityOn-time
LufthansaCheapest$497Average$1,362FlexibilityNo cancel feeOn-time76%
DeltaCheapest$503Average$1,247FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$575Average$1,168FlexibilityNo cancel feeOn-time69%
British AirwaysCheapest$609Average$1,026FlexibilityNo cancel feeOn-time70%
KLMCheapest$625Average$945FlexibilityNo cancel feeOn-time75%
American AirlinesCheapest$765Average$1,320FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.