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Italy

$209+ Cheap flights from South Carolina to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/3. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — NAP
Mar 17 — Mar 241
Tue 3/17
Tue 3/24
1 adult, Economy
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Cheap flight deals from South Carolina to Italy

Cheapest flights from South Carolina to Italy
Explore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 15, 2026.

This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1110:23 am
CHS
-
MXP
2 stops17h 57m
United Airlines
Thu 8/2012:20 pm
MXP
-
CHS
2 stops38h 44m
United Airlines
Deal found 2/11$476
This United Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/91:52 pm
CLT
-
MXP
1 stop12h 38m
United Airlines
Tue 3/1712:05 pm
MXP
-
CLT
2 stops40h 52m
United Airlines
Deal found 2/13$487
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:30 am
CLT
-
MXP
2 stops21h 50m
United Airlines
Thu 8/2712:20 pm
MXP
-
CLT
2 stops37h 59m
United Airlines
Deal found 2/11$491
This Air Canada deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/97:50 am
CLT
-
MXP
2 stops20h 05m
Air Canada
Tue 3/1712:05 pm
MXP
-
CLT
2 stops31h 06m
Air Canada
Deal found 2/12$494
This United Airlines deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1010:26 am
CLT
-
VCE
1 stop15h 29m
United Airlines
Fri 8/2111:05 am
VCE
-
CLT
1 stop15h 14m
United Airlines
Deal found 2/14$494
This American Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/1511:00 pm
CLT
-
MXP
1 stop15h 00m
American Airlines
Tue 3/310:25 am
MXP
-
CLT
1 stop16h 35m
American Airlines
Deal found 2/13$495
This United Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/176:00 am
CLT
-
MXP
2 stops28h 40m
United Airlines
Wed 8/2612:20 pm
MXP
-
CLT
2 stops37h 59m
United Airlines
Deal found 2/13$496
This lol.travel deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/168:16 am
CLT
-
MXP
1 stop17h 49m
Finnair
Tue 3/310:25 am
MXP
-
CLT
1 stop17h 11m
Finnair
Deal found 2/13$497
This United Airlines deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1110:23 am
CLT
-
VCE
1 stop15h 32m
United Airlines
Wed 8/196:30 am
VCE
-
CLT
2 stops20h 27m
United Airlines
Deal found 2/14$497
This United Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/157:01 am
CLT
-
MXP
1 stop18h 29m
United Airlines
Tue 3/39:45 am
MXP
-
CLT
2 stops15h 10m
United Airlines
Deal found 2/13$498
This Delta deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:59 pm
CLT
-
VCE
2 stops16h 51m
Delta
Thu 8/2011:05 am
VCE
-
CLT
1 stop16h 33m
Delta
Deal found 2/14$498
This United Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/1611:07 am
CLT
-
MXP
1 stop14h 23m
United Airlines
Tue 3/39:45 am
MXP
-
CLT
2 stops15h 10m
United Airlines
Deal found 2/15$499

Find flight deals from South Carolina to Italy

Keep the following information in mind while searching for South Carolina to Italy flight deals. Data was last updated February 15, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$476
(United Airlines)

One-way from

$209
(oojo)

Popular in

June

Cheapest in

January

Average price

$844
Provider with most accurate pricing for Myrtle Beach Intl-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Rome (ROM) flights.
Search Deals
From South Carolina to Italy
Search Deals
One-way flight from South Carolina to Italy
Search Deals
Highest demand for flights based on searches. 30% potential increase in price ($487 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 9% potential price decrease ($94 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 15, 2026.
Use the filters below to find and compare flights from South Carolina to Italy that are best for you.

Fly from

South Carolina

Fly to

Italy

Route

Depart

Return

Price

CharlestonMilan

CHS - MXP

CHSMXP

Charleston

Tue 8/11

10:23 am-10:20 am

2 stops17h 57m

Milan Malpensa

Thu 8/20

12:20 pm-9:04 pm

2 stops38h 44m

$476

CharlotteMilan

CLT - MXP

CLTMXP

Charlotte Douglas

Mon 3/9

1:52 pm-7:30 am

1 stop12h 38m

Milan Malpensa

Tue 3/17

12:05 pm-1:09 pm

2 stops30h 04m

$487

CharlotteMilan

CLT - MXP

CLTMXP

Charlotte Douglas

Mon 3/9

7:50 am-8:55 am

2 stops20h 05m

Milan Malpensa

Tue 3/17

12:05 pm-2:11 pm

2 stops31h 06m

$494

CharlotteVenice

CLT - VCE

CLTVCE

Charlotte Douglas

Mon 8/10

10:26 am-7:55 am

1 stop15h 29m

Venice Marco Polo

Fri 8/21

11:05 am-8:19 pm

1 stop15h 14m

$494

CharlotteVenice

CLT - VCE

CLTVCE

Charlotte Douglas

Tue 8/11

2:50 pm-7:55 am

1 stop11h 05m

Venice Marco Polo

Thu 8/20

9:40 am-11:34 pm

1 stop19h 54m

$494

CharlotteVenice

CLT - VCE

CLTVCE

Charlotte Douglas

Tue 8/11

10:23 am-7:55 am

1 stop15h 32m

Venice Marco Polo

Wed 8/19

6:30 am-8:57 pm

2 stops20h 27m

$497

CharlotteMilan

CLT - MXP

CLTMXP

Charlotte Douglas

Wed 2/25

11:00 pm-8:00 pm

1 stop15h 00m

Milan Malpensa

Wed 3/4

10:25 am-9:36 pm

1 stop17h 11m

$499

CharlestonMilan

CHS - MXP

CHSMXP

Charleston

Wed 3/18

12:47 pm-6:30 am

1 stop12h 43m

Milan Malpensa

Mon 3/30

6:45 am-3:46 pm

2 stops15h 01m

$503

CharlestonMilan

CHS - MXP

CHSMXP

Charleston

Tue 8/11

6:43 pm-10:20 am

3 stops33h 37m

Milan Malpensa

Thu 8/20

12:20 pm-10:28 am

2 stops28h 08m

$504

CharlestonMilan

CHS - MXP

CHSMXP

Charleston

Wed 3/18

12:47 pm-11:40 am

2 stops17h 53m

Milan Malpensa

Mon 3/30

6:45 am-5:09 pm

2 stops16h 24m

$507

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/13

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Italy

What is the cheapest month to book a flight from South Carolina to Italy?

Currently, October is the cheapest month in which you can book a flight from South Carolina to Italy (average of $181). Flying from South Carolina to Italy in July is currently the most expensive (average of $775). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to IT?

Find hourly flight availability from South Carolina to Italy. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 15, 2026.

One of the essential ways to save on airfare from South Carolina to Italy is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 33% on airfare.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Italy?

    For as low as $499, United Airlines can have you in Italy from South Carolina in 15h. The distance from South Carolina to Italy is about 4519 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from South Carolina to Italy one-way?

    $298 is the cheapest one-way deal found within the past few days, from Neos Air. You may also be able to find cheap deals on Aeromexico and Air France, with prices starting from $381 and $454, respectively.

  • Can I find deals for flights from South Carolina to Italy that include hotel bookings?

    Yes. In addition to deals on South Carolina to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Italy.

  • Can I find deals for business class flights from South Carolina to Italy?

    Yes. Cheapflights offers flight deals from South Carolina to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Italy?

    Currently, October is the cheapest month in which you can book a flight from South Carolina to Italy (average of $181). Flying from South Carolina to Italy in July is currently the most expensive (average of $775). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Italy

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from South Carolina to Italy

Discover the top 6 airlines that operate flights from South Carolina to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 15, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$307Average$1,103FlexibilityNo cancel feeOn-time69%
DeltaCheapest$457Average$1,137FlexibilityNo cancel feeOn-timeN/A
KLMCheapest$507Average$1,012FlexibilityNo cancel feeOn-time75%
LufthansaCheapest$591Average$1,119FlexibilityNo cancel feeOn-time76%
British AirwaysCheapest$609Average$931FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$674Average$1,117FlexibilityNo cancel feeOn-time71%

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