South Carolina

$377+ Cheap flights from Italy to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/15. Fares are subject to change and may not be available on all flights or dates of travel.
NAP — CHS
Jul 14 — Jul 211
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Cheap flight deals from Italy to South Carolina

Cheapest flights from Italy to South Carolina
Explore the most affordable flight options available from Italy to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 14, 2026.

This lol.travel deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/410:20 am
MXP
-
CLT
1 stop17h 15m
Finnair
Sun 11/88:12 am
CLT
-
MXP
1 stop17h 53m
Finnair
Deal found 6/13$672
This lol.travel deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:00 pm
MXP
-
CHS
2 stops33h 34m
Finnair
Thu 11/1912:26 pm
CHS
-
MXP
2 stops23h 49m
Finnair
Deal found 6/12$693
This lol.travel deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1510:00 am
FCO
-
CLT
1 stop15h 15m
Finnair
Tue 9/228:10 pm
CLT
-
FCO
Nonstop9h 10m
Finnair
Deal found 6/10$719
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/212:20 pm
MXP
-
CLT
1 stop13h 35m
American Airlines
Sat 9/1211:05 pm
CLT
-
MXP
1 stop18h 30m
American Airlines
Deal found 6/9$742
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/242:20 pm
MXP
-
CLT
1 stop13h 35m
American Airlines
Thu 9/108:20 pm
CLT
-
MXP
1 stop21h 15m
American Airlines
Deal found 6/10$743
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/23:00 pm
NAP
-
CHS
2 stops27h 27m
American Airlines
Sun 9/612:23 pm
CHS
-
NAP
2 stops27h 37m
American Airlines
Deal found 6/12$743
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/42:20 pm
MXP
-
CHS
1 stop15h 34m
American Airlines
Tue 9/87:48 pm
CHS
-
MXP
2 stops16h 02m
American Airlines
Deal found 6/9$743
This American Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1310:20 am
MXP
-
CLT
1 stop17h 15m
American Airlines
Sun 11/158:15 pm
CLT
-
MXP
1 stop17h 45m
American Airlines
Deal found 6/13$744
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/241:40 pm
VCE
-
CLT
1 stop26h 50m
American Airlines
Mon 9/148:20 pm
CLT
-
VCE
1 stop17h 40m
American Airlines
Deal found 6/11$744
This American Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1411:05 am
MXP
-
CHS
2 stops16h 16m
American Airlines
Sun 10/181:12 pm
CHS
-
MXP
2 stops28h 23m
American Airlines
Deal found 6/13$744
This British Airways deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/142:20 pm
MXP
-
CHS
1 stop15h 26m
British Airways
Tue 9/227:41 pm
CHS
-
MXP
2 stops16h 09m
British Airways
Deal found 6/10$745
This British Airways deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/241:40 pm
VCE
-
CLT
1 stop14h 15m
British Airways
Mon 9/145:57 pm
CLT
-
VCE
2 stops13h 53m
British Airways
Deal found 6/11$746

Find flight deals from Italy to South Carolina

Keep the following information in mind while searching for Italy to South Carolina flight deals. Data was last updated June 14, 2026.

Round-trip from

$652
(Ovago)

One-way from

$377
(Kiwi.com)
From Italy to South Carolina
One-way flight from Italy to South Carolina

Cheapflights Fare Finder

 
Customize your flight search to find flights from Italy to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 14, 2026.
Use the filters below to find and compare flights from Italy to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

NaplesCharleston

NAP - CHS

NAPCHS

Naples

Wed 9/2

3:00 pm-11:33 am

1 stop26h 33m

Charleston

Sun 9/6

12:23 pm-10:00 pm

2 stops27h 37m

$743

MilanCharleston

MXP - CHS

MXPCHS

Milan Malpensa

Fri 9/4

1:20 pm-11:59 pm

1 stop16h 39m

Charleston

Tue 9/8

1:12 pm-11:40 pm

2 stops28h 28m

$743

MilanCharlotte

MXP - CLT

MXPCLT

Milan Malpensa

Fri 11/13

10:20 am-7:05 pm

2 stops14h 45m

Charlotte Douglas

Sun 11/15

6:25 pm-8:00 pm

1 stop19h 35m

$744

MilanCharleston

MXP - CHS

MXPCHS

Milan Malpensa

Wed 10/14

11:05 am-9:21 pm

2 stops16h 16m

Charleston

Sun 10/18

1:12 pm-11:35 pm

2 stops28h 23m

$744

MilanCharleston

MXP - CHS

MXPCHS

Milan Malpensa

Mon 9/14

2:20 pm-11:46 pm

1 stop15h 26m

Charleston

Tue 9/22

7:41 pm-5:50 pm

2 stops16h 09m

$745

MilanCharleston

MXP - CHS

MXPCHS

Milan Malpensa

Wed 10/14

1:20 pm-11:59 pm

1 stop16h 39m

Charleston

Sun 10/18

6:36 pm-6:35 pm

2 stops17h 59m

$746

VeniceCharlotte

VCE - CLT

VCECLT

Venice Marco Polo

Mon 8/24

1:40 pm-9:55 pm

1 stop14h 15m

Charlotte Douglas

Mon 9/14

5:57 pm-1:50 pm

2 stops13h 53m

$747

MilanCharlotte

LIN - CLT

LINCLT

Milan Linate

Fri 9/4

11:40 am-8:41 am

2 stops27h 01m

Charlotte Douglas

Sun 9/6

11:15 pm-10:10 am

1 stop28h 55m

$750

MilanCharlotte

MXP - CLT

MXPCLT

Milan Malpensa

Thu 8/20

9:45 pm-1:15 pm

1 stop21h 30m

Charlotte Douglas

Sat 9/12

11:05 pm-11:35 pm

1 stop18h 30m

$751

MilanCharlotte

MXP - CLT

MXPCLT

Milan Malpensa

Wed 11/4

12:00 pm-11:53 pm

2 stops17h 53m

Charlotte Douglas

Sun 11/8

7:05 pm-5:25 pm

2 stops16h 20m

$752

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/13

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Italy to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Italy with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Italy to South Carolina
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Italy to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Italy to South Carolina?

    A quick flight from Italy to South Carolina can take about 15h 26m. Finnair provides one of the quickest options available for as low as $745. The distance from Italy to South Carolina is about 4582 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Italy to South Carolina one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $182. United Airlines flights start at $269 while deals on Aeromexico start at $292 one-way.

  • Can I find deals for flights from Italy to South Carolina that include hotel bookings?

    Yes. In addition to deals on Italy to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Italy to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Italy to South Carolina.

  • Can I find deals for business class flights from Italy to South Carolina?

    Yes. Cheapflights offers flight deals from Italy to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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