South Carolina

$353+ Cheap flights from Italy to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/20. Fares are subject to change and may not be available on all flights or dates of travel.
NAP — CHS
May 25 — Jun 11
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Cheap flight deals from Italy to South Carolina

Cheapest flights from Italy to South Carolina
Explore the most affordable flight options available from Italy to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 25, 2026.

This deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:05 am
MXP
-
CLT
1 stop14h 19m
American Airlines
Wed 9/302:27 pm
CLT
-
MXP
1 stop12h 38m
American Airlines
Deal found 4/22$715
This lol.travel deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/211:00 am
MXP
-
CLT
1 stop16h 52m
Finnair
Thu 5/711:26 am
CLT
-
MXP
1 stop15h 39m
Finnair
Deal found 4/22$750
This lol.travel deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/111:00 am
MXP
-
CLT
1 stop16h 52m
Finnair
Tue 5/58:00 am
CLT
-
MXP
1 stop19h 05m
Finnair
Deal found 4/20$752
This lol.travel deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3011:00 am
MXP
-
CLT
1 stop16h 52m
Finnair
Fri 5/88:10 am
CLT
-
MXP
1 stop18h 55m
Finnair
Deal found 4/22$756
This lol.travel deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2711:00 am
MXP
-
CLT
1 stop16h 52m
Finnair
Tue 5/511:22 am
CLT
-
MXP
1 stop15h 43m
Finnair
Deal found 4/20$765
This lol.travel deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3012:15 pm
VCE
-
CLT
1 stop13h 25m
British Airways
Tue 5/54:42 pm
CLT
-
VCE
1 stop11h 13m
British Airways
Deal found 4/22$769
This lol.travel deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/79:40 am
BLQ
-
CLT
2 stops30h 35m
Multiple Airlines
Mon 5/115:55 pm
CLT
-
BLQ
1 stop18h 55m
Multiple Airlines
Deal found 4/21$775
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/910:10 am
FCO
-
CLT
1 stop15h 03m
Multiple Airlines
Wed 5/137:12 am
CLT
-
FCO
1 stop17h 28m
Multiple Airlines
Deal found 4/23$782
This lol.travel deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1111:30 am
FCO
-
CLT
2 stops33h 27m
Air Canada
Tue 5/269:20 am
CLT
-
FCO
2 stops17h 30m
Air Canada
Deal found 4/22$785
This Mytrip deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:00 pm
LIN
-
CLT
3 stops35h 44m
Multiple Airlines
Tue 5/57:12 am
CLT
-
LIN
3 stops28h 58m
Multiple Airlines
Deal found 4/20$797
This lol.travel deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/212:15 pm
VCE
-
CLT
1 stop13h 25m
British Airways
Wed 5/64:42 pm
CLT
-
VCE
1 stop11h 13m
British Airways
Deal found 4/24$799
This lol.travel deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/112:15 pm
FCO
-
CLT
Nonstop10h 35m
Finnair
Tue 5/268:34 am
CLT
-
FCO
1 stop19h 16m
Finnair
Deal found 4/22$812

Find flight deals from Italy to South Carolina

Keep the following information in mind while searching for Italy to South Carolina flight deals. Data was last updated April 25, 2026.

Round-trip from

$715

One-way from

$353
(Kiwi.com)
From Italy to South Carolina
One-way flight from Italy to South Carolina

Cheapflights Fare Finder

 
Customize your flight search to find flights from Italy to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 25, 2026.
Use the filters below to find and compare flights from Italy to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MilanCharlotte

MXP - CLT

MXPCLT

Milan Malpensa

Thu 9/3

9:00 am-11:58 pm

2 stops20h 58m

Charlotte Douglas

Sun 9/6

7:00 am-7:30 am

1 stop18h 30m

$825

BolognaCharlotte

BLQ - CLT

BLQCLT

Bologna Guglielmo Marconi

Thu 9/10

6:50 am-7:40 pm

2 stops18h 50m

Charlotte Douglas

Mon 9/14

8:20 pm-6:50 pm

1 stop16h 30m

$826

BolognaCharlotte

BLQ - CLT

BLQCLT

Bologna Guglielmo Marconi

Thu 9/10

10:20 am-8:14 pm

2 stops15h 54m

Charlotte Douglas

Mon 9/14

11:17 am-9:15 am

2 stops15h 58m

$826

BolognaCharlotte

BLQ - CLT

BLQCLT

Bologna Guglielmo Marconi

Thu 5/7

10:20 am-11:59 pm

2 stops19h 39m

Charlotte Douglas

Mon 5/11

2:50 pm-4:30 pm

2 stops19h 40m

$828

BolognaCharlotte

BLQ - CLT

BLQCLT

Bologna Guglielmo Marconi

Thu 5/7

7:50 am-8:45 pm

1 stop18h 55m

Charlotte Douglas

Mon 5/11

5:55 pm-6:50 pm

1 stop18h 55m

$829

VeniceCharlotte

VCE - CLT

VCECLT

Venice Marco Polo

Mon 8/24

10:55 am-11:58 pm

2 stops19h 03m

Charlotte Douglas

Mon 9/14

5:55 pm-2:00 pm

2 stops14h 05m

$829

MilanCharleston

MXP - CHS

MXPCHS

Milan Malpensa

Thu 9/24

11:20 am-12:06 am

2 stops18h 46m

Charleston

Mon 9/28

6:00 am-7:30 am

2 stops19h 30m

$829

MilanCharleston

MXP - CHS

MXPCHS

Milan Malpensa

Thu 9/24

2:20 pm-11:55 pm

1 stop15h 35m

Charleston

Mon 9/28

4:46 pm-1:45 pm

2 stops14h 59m

$830

BolognaCharlotte

BLQ - CLT

BLQCLT

Bologna Guglielmo Marconi

Thu 9/3

6:50 am-3:55 pm

1 stop15h 05m

Charlotte Douglas

Sun 9/6

11:20 am-11:45 am

2 stops18h 25m

$833

MilanCharlotte

LIN - CLT

LINCLT

Milan Linate

Fri 9/11

7:50 am-7:40 pm

2 stops17h 50m

Charlotte Douglas

Tue 9/15

8:20 pm-9:35 pm

1 stop19h 15m

$833

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/22

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Italy to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Italy with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Italy to South Carolina
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Italy to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Italy to South Carolina?

    A quick flight from Italy to South Carolina can take about 16h 09m. United Airlines provides one of the quickest options available for as low as $837. The distance from Italy to South Carolina is about 4678 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Italy to South Carolina one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $182. United Airlines flights start at $276 while deals on Aeromexico start at $292 one-way.

  • Can I find deals for flights from Italy to South Carolina that include hotel bookings?

    Yes. In addition to deals on Italy to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Italy to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Italy to South Carolina.

  • Can I find deals for business class flights from Italy to South Carolina?

    Yes. Cheapflights offers flight deals from Italy to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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