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$143+ Cheap flights from San Francisco (SFO) to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/25. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — DSM
Dec 17 — Dec 241
Wed 12/17
Wed 12/24
1 adult, Economy
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Cheap flight deals from San Francisco to Iowa

Keep the following information in mind while searching for San Francisco to Iowa flight deals. Data was last updated November 17, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$134
(Expedia)

Popular in

October

Cheapest in

September

Average price

$566
Provider with most accurate pricing for San Francisco-Des Moines flight deals.
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Provider most trusted by Cheapflights users for San Francisco-Des Moines flights.
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From San Francisco to Iowa
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($18 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from San Francisco to Iowa

Cheapest flights from San Francisco to Iowa
Explore the most affordable flight options available from San Francisco to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 17, 2025.

This Priceline deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/58:48 amSFO - DSM
1 stop8h 15mFrontier
Mon 12/87:58 pmDSM - SFO
1 stop6h 26mFrontier
Deal found 11/15$184
This Kiwi.com deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/58:48 amSFO - DSM
1 stop8h 15mMultiple Airlines
Mon 12/87:28 pmDSM - SFO
1 stop23h 23mMultiple Airlines
Deal found 11/15$204
This United Airlines deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/124:55 pmSFO - OMA
Nonstop3h 25mUnited Airlines
Sun 12/147:34 amOMA - SFO
Nonstop4h 11mUnited Airlines
Deal found 11/15$249
This Alaska Airlines deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/97:25 pmSFO - OMA
1 stop16h 49mAlaska Airlines
Fri 12/123:10 pmOMA - SFO
1 stop9h 35mAlaska Airlines
Deal found 11/17$252
This Expedia deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/56:30 amSFO - OMA
1 stop5h 01mFrontier
Sun 12/72:18 pmOMA - SFO
1 stop12h 06mFrontier
Deal found 11/17$254
This Delta deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/512:30 amSFO - OMA
1 stop9h 14mDelta
Fri 12/125:07 amOMA - SFO
1 stop11h 40mDelta
Deal found 11/16$269
This Expedia deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/3010:17 pmSFO - OMA
1 stop10h 14mFrontier
Thu 12/42:24 pmOMA - SFO
1 stop19h 29mFrontier
Deal found 11/14$271
This CheapOair deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/88:48 amSFO - DSM
1 stop8h 15mFrontier
Fri 12/127:58 pmDSM - SFO
1 stop6h 26mFrontier
Deal found 11/16$272
This Alaska Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/66:13 pmSFO - OMA
2 stops18h 01mAlaska Airlines
Fri 12/123:10 pmOMA - SFO
1 stop9h 35mAlaska Airlines
Deal found 11/16$289
This Delta deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/63:33 pmSFO - CID
1 stop5h 46mDelta
Mon 12/86:25 amCID - SFO
1 stop9h 08mDelta
Deal found 11/15$289
This Frontier deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:30 amSFO - OMA
1 stop5h 01mFrontier
Sun 12/72:18 pmOMA - SFO
1 stop12h 06mFrontier
Deal found 11/17$292
This American Airlines deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/66:00 amSFO - CID
1 stop6h 06mAmerican Airlines
Mon 12/81:28 pmCID - SFO
2 stops8h 55mAmerican Airlines
Deal found 11/15$294

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 17, 2025.
Use the filters below to find and compare flights from San Francisco to Iowa that are best for you.

Fly from

San Francisco

Fly to

Iowa

Route

Depart

Return

Price

San FranciscoDes Moines

SFO - DSM

SFODSM

San Francisco

Fri 12/5

8:48 am-7:03 pm

1 stop8h 15m

Des Moines

Mon 12/8

7:58 pm-12:24 am

1 stop6h 26m

$184

San FranciscoOmaha

SFO - OMA

SFOOMA

San Francisco

Wed 2/11

12:00 pm-2:15 pm

1 stop24h 15m

Omaha Eppley Airfield

Sun 2/15

3:11 pm-9:55 pm

1 stop8h 44m

$252

San FranciscoOmaha

SFO - OMA

SFOOMA

San Francisco

Tue 12/9

7:25 pm-2:14 pm

1 stop16h 49m

Omaha Eppley Airfield

Fri 12/12

3:10 pm-10:45 pm

1 stop9h 35m

$252

San FranciscoSioux City

SFO - SUX

SFOSUX

San Francisco

Thu 1/22

4:31 pm-11:47 pm

1 stop5h 16m

Sioux City Sioux Gateway

Sun 1/25

6:00 am-9:45 am

1 stop5h 45m

$254

San FranciscoOmaha

SFO - OMA

SFOOMA

San Francisco

Thu 1/8

4:22 pm-9:53 pm

Nonstop3h 31m

Omaha Eppley Airfield

Sun 1/11

5:52 am-9:45 am

1 stop5h 53m

$259

San FranciscoOmaha

SFO - OMA

SFOOMA

San Francisco

Fri 12/5

12:30 am-11:44 am

1 stop9h 14m

Omaha Eppley Airfield

Fri 12/12

5:07 am-2:47 pm

1 stop11h 40m

$269

San FranciscoDes Moines

SFO - DSM

SFODSM

San Francisco

Mon 12/8

8:48 am-7:03 pm

1 stop8h 15m

Des Moines

Fri 12/12

7:58 pm-12:24 am

1 stop6h 26m

$272

San FranciscoCedar Rapids

SFO - CID

SFOCID

San Francisco

Sat 12/6

3:33 pm-11:19 pm

1 stop5h 46m

Cedar Rapids

Mon 12/8

6:25 am-1:33 pm

1 stop9h 08m

$289

San FranciscoCedar Rapids

SFO - CID

SFOCID

San Francisco

Sat 12/6

6:00 am-2:06 pm

1 stop6h 06m

Cedar Rapids

Mon 12/8

1:28 pm-8:23 pm

2 stops8h 55m

$294

San FranciscoOmaha

SFO - OMA

SFOOMA

San Francisco

Wed 12/3

2:00 pm-12:16 am

1 stop8h 16m

Omaha Eppley Airfield

Sun 12/7

9:00 am-1:33 pm

1 stop6h 33m

$299

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/16

Showing 1-10 of 56 results
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Best time to book a flight from San Francisco to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Iowa

What is the cheapest month to book a flight from San Francisco to Iowa?

Currently, September is the cheapest month in which you can book a flight from San Francisco to Iowa (average of $149). Flying from San Francisco to Iowa in February is currently the most expensive (average of $331). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to IA?

Find hourly flight availability from San Francisco to Iowa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 17, 2025.

A simple way to save on the total cost of your ticket is to fly from San Francisco to Iowa at noon. If you’re flexible enough to do this you can expect to save up to 18% on your trip compared to booking a flight in the evening.

What is the cheapest day to fly from San Francisco to Iowa?

Use this chart to determine the cheapest time to fly round-trip from San Francisco to Iowa. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their San Francisco to Iowa flight should consider departing on Wednesday evenings when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated November 17, 2025.
See what other customers who have flown with Southwest, Delta, and United Airlines from San Francisco to Iowa have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,244 reviews

Boarding

8.1

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
8.0
Very good
4,244 reviews
Southwest
8.0
Very good
4,244 reviews

Boarding

8.1

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Delta
7.9
Good
8,007 reviews
Southwest
8.0
Very good
4,244 reviews

Boarding

8.1

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
United Airlines
7.4
Good
9,013 reviews
Southwest
8.0
Very good
4,244 reviews

Boarding

8.1

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
American Airlines
7.2
Good
11,050 reviews
Southwest
8.0
Very good
4,244 reviews

Boarding

8.1

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Frontier
5.8
Fair
3,106 reviews
Southwest
8.0
Very good
4,244 reviews

Boarding

8.1

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Francisco to Iowa?

    Most people fly from San Francisco (SFO) if they book a flight from San Francisco to Iowa. San Francisco is conveniently located just 11.8 mi from San Francisco’s city center.

  • How long is the flight from San Francisco to Iowa?

    For as low as $254, Frontier can have you in Iowa from San Francisco in 5h 16m. There are 1408 mi between San Francisco and Iowa. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from San Francisco to Iowa one-way?

    $143 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on United Airlines and American Airlines, with prices starting from $149 and $180, respectively.

  • What are the most popular routes from San Francisco to Iowa?

    When deciding which route to take from San Francisco to Iowa consider San Francisco - Omaha Eppley Airfield, San Francisco - Des Moines or San Francisco - Cedar Rapids as they are the most popular.

  • Can I find deals for flights from San Francisco to Iowa that include hotel bookings?

    Yes. In addition to deals on San Francisco to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Iowa.

  • Can I find deals for business class flights from San Francisco to Iowa?

    Yes. Cheapflights offers flight deals from San Francisco to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Iowa?

    Currently, September is the cheapest month in which you can book a flight from San Francisco to Iowa (average of $149). Flying from San Francisco to Iowa in February is currently the most expensive (average of $331). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for San Francisco to Iowa

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from San Francisco to Iowa

Discover the top 5 airlines that operate flights from San Francisco to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$149Average$331FlexibilityNo cancel feeOn-time62%
DeltaCheapest$272Average$416FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$288Average$507FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$288Average$477FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$356Average$435FlexibilityNo cancel feeOn-time63%

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