Iowa

$82+ Cheap flights from San Francisco (SFO) to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/23. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — DSM
Feb 20 — Feb 271
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Cheap flight deals from San Francisco to Iowa

Cheapest flights from San Francisco to Iowa
Explore the most affordable flight options available from San Francisco to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2026.

This Frontier deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/186:55 am
SFO
-
OMA
1 stop7h 10m
Frontier
Mon 2/231:59 pm
OMA
-
SFO
1 stop9h 40m
Frontier
Deal found 1/19$154
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/116:55 am
SFO
-
OMA
1 stop7h 10m
Frontier
Wed 2/185:00 pm
OMA
-
SFO
2 stops16h 20m
Frontier
Deal found 1/20$158
This Frontier deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1911:09 pm
SFO
-
OMA
1 stop11h 55m
Frontier
Mon 2/231:59 pm
OMA
-
SFO
1 stop9h 40m
Frontier
Deal found 1/19$180
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/117:15 pm
SFO
-
OMA
2 stops13h 22m
Frontier
Mon 2/167:19 pm
OMA
-
SFO
1 stop28h 42m
Frontier
Deal found 1/19$192
This CheapOair deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/196:15 am
SFO
-
DSM
1 stop10h 32m
Frontier
Mon 2/237:17 pm
DSM
-
SFO
1 stop28h 44m
Frontier
Deal found 1/20$201
This Expedia deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/28:47 pm
SFO
-
OMA
1 stop15h 28m
Alaska Airlines
Tue 3/103:11 pm
OMA
-
SFO
1 stop7h 25m
Alaska Airlines
Deal found 1/20$229
This Frontier deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:15 am
SFO
-
CID
1 stop10h 57m
Frontier
Sun 3/17:36 pm
CID
-
SFO
1 stop6h 52m
Frontier
Deal found 1/20$235
This Expedia deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/269:04 pm
SFO
-
OMA
1 stop21h 15m
Frontier
Mon 3/309:04 pm
OMA
-
SFO
1 stop5h 25m
Frontier
Deal found 1/21$238
This Expedia deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/106:18 pm
SFO
-
OMA
1 stop17h 53m
Multiple Airlines
Mon 2/167:19 pm
OMA
-
SFO
1 stop28h 42m
Multiple Airlines
Deal found 1/19$245
This Booking.com deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/89:00 pm
SFO
-
OMA
1 stop21h 14m
Frontier
Sun 4/128:59 pm
OMA
-
SFO
1 stop5h 24m
Frontier
Deal found 1/21$246
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/128:43 am
SFO
-
OMA
1 stop25h 01m
Multiple Airlines
Mon 2/167:19 pm
OMA
-
SFO
1 stop28h 42m
Multiple Airlines
Deal found 1/19$247
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/136:00 am
SFO
-
CID
1 stop7h 27m
Multiple Airlines
Fri 3/2012:57 pm
CID
-
SFO
1 stop9h 24m
Multiple Airlines
Deal found 1/20$260

Find flight deals from San Francisco to Iowa

Keep the following information in mind while searching for San Francisco to Iowa flight deals. Data was last updated January 21, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$154
(Frontier)

One-way from

$82
(Kiwi.com)

Popular in

January

Cheapest in

September

Average price

$731
Provider with most accurate pricing for San Francisco-Des Moines flight deals.
Provider most trusted by Cheapflights users for San Francisco-Des Moines flights.
From San Francisco to Iowa
One-way flight from San Francisco to Iowa
Highest demand for flights based on searches. 16% potential increase in price ($99 potential increase over avg. RT price).
Cheapest flight prices on average. 4% potential price decrease ($23 potential savings vs. average RT price).
Average for round-trip flights in January 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
Use the filters below to find and compare flights from San Francisco to Iowa that are best for you.

Fly from

San Francisco

Fly to

Iowa

Route

Depart

Return

Price

San FranciscoDes Moines

SFO - DSM

SFODSM

San Francisco

Thu 2/19

6:15 am-6:47 pm

1 stop10h 32m

Des Moines

Mon 2/23

7:17 pm-10:01 pm

1 stop28h 44m

$201

San FranciscoCedar Rapids

SFO - CID

SFOCID

San Francisco

Thu 2/26

6:15 am-7:12 pm

1 stop10h 57m

Cedar Rapids

Sun 3/1

7:36 pm-12:28 am

1 stop6h 52m

$235

San FranciscoOmaha

SFO - OMA

SFOOMA

San Francisco

Tue 3/10

12:55 pm-6:26 pm

Nonstop3h 31m

Omaha Eppley Airfield

Tue 3/17

7:23 am-9:45 am

Nonstop4h 22m

$249

San FranciscoOmaha

SFO - OMA

SFOOMA

San Francisco

Thu 2/12

5:10 am-12:40 pm

1 stop5h 30m

Omaha Eppley Airfield

Mon 2/16

7:23 am-9:45 am

Nonstop4h 22m

$259

San FranciscoOmaha

SFO - OMA

SFOOMA

San Francisco

Wed 2/11

9:50 am-4:52 pm

1 stop5h 02m

Omaha Eppley Airfield

Tue 2/17

5:50 pm-11:54 pm

1 stop8h 04m

$269

San FranciscoOmaha

SFO - OMA

SFOOMA

San Francisco

Fri 5/1

10:35 pm-10:39 am

1 stop10h 04m

Omaha Eppley Airfield

Sat 5/2

5:55 pm-10:15 pm

1 stop6h 20m

$269

San FranciscoOmaha

SFO - OMA

SFOOMA

San Francisco

Fri 5/22

6:00 am-5:45 pm

1 stop9h 45m

Omaha Eppley Airfield

Wed 5/27

6:15 pm-11:52 pm

1 stop7h 37m

$270

San FranciscoOmaha

SFO - OMA

SFOOMA

San Francisco

Tue 3/10

6:45 am-4:45 pm

2 stops8h 00m

Omaha Eppley Airfield

Tue 3/17

1:55 pm-9:05 pm

1 stop9h 10m

$274

San FranciscoSioux City

SFO - SUX

SFOSUX

San Francisco

Tue 6/2

5:20 am-5:32 pm

1 stop10h 12m

Sioux City Sioux Gateway

Sun 6/7

6:00 am-9:29 am

1 stop5h 29m

$274

San FranciscoDes Moines

SFO - DSM

SFODSM

San Francisco

Wed 2/4

9:44 am-3:40 pm

1 stop27h 56m

Des Moines

Sun 2/8

8:30 am-12:54 pm

2 stops30h 24m

$276

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Showing 1-10 of 52 results
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Best time to book a flight from San Francisco to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Iowa

What is the cheapest month to book a flight from San Francisco to Iowa?

Currently, September is the cheapest month in which you can book a flight from San Francisco to Iowa (average of $149). Flying from San Francisco to Iowa in January is currently the most expensive (average of $317). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated January 21, 2026.
See what other customers who have flown with Southwest, Delta, and United Airlines from San Francisco to Iowa have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Crew

8.6

Food

7.0

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Overall

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Crew

8.6

Food

7.0

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Overall

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Crew

8.6

Food

7.0

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Overall

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Crew

8.6

Food

7.0

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Overall

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Crew

8.6

Food

7.0

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Overall

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Crew

8.6

Food

7.0

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Overall

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from San Francisco to Iowa?

    Most people fly from San Francisco (SFO) if they book a flight from San Francisco to Iowa. San Francisco is conveniently located just 11.8 mi from San Francisco’s city center.

  • How long is the flight from San Francisco to Iowa?

    For as low as $249, Frontier can have you in Iowa from San Francisco in 3h 31m. There are 1429 mi between San Francisco and Iowa. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from San Francisco to Iowa one-way?

    $75 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on Delta and Southwest, with prices starting from $128 and $143, respectively.

  • What are the most popular routes from San Francisco to Iowa?

  • Can I find deals for flights from San Francisco to Iowa that include hotel bookings?

    Yes. In addition to deals on San Francisco to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Iowa.

  • Can I find deals for business class flights from San Francisco to Iowa?

    Yes. Cheapflights offers flight deals from San Francisco to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Iowa?

    Currently, September is the cheapest month in which you can book a flight from San Francisco to Iowa (average of $149). Flying from San Francisco to Iowa in January is currently the most expensive (average of $317). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for San Francisco to Iowa

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from San Francisco to Iowa

Discover the top 5 airlines that operate flights from San Francisco to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$149Average$321FlexibilityNo cancel feeOn-time62%
DeltaCheapest$263Average$416FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$288Average$559FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$288Average$476FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$346Average$426FlexibilityNo cancel feeOn-time63%

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