Iowa

$91+ Cheap flights from San Francisco (SFO) to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/13. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — DSM
Apr 11 — Apr 181
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Cheap flight deals from San Francisco to Iowa

Cheapest flights from San Francisco to Iowa
Explore the most affordable flight options available from San Francisco to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 12, 2026.

This Expedia deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:00 am
SFO
-
OMA
1 stop12h 14m
Frontier
Mon 4/138:59 pm
OMA
-
SFO
1 stop5h 29m
Frontier
Deal found 3/7$190
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:00 am
SFO
-
OMA
1 stop12h 14m
Frontier
Mon 4/208:58 pm
OMA
-
SFO
1 stop28h 27m
Frontier
Deal found 3/7$195
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/314:35 pm
SFO
-
OMA
1 stop5h 10m
American Airlines
Wed 4/83:21 pm
OMA
-
SFO
1 stop5h 59m
American Airlines
Deal found 3/9$209
This Frontier deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:00 am
SFO
-
OMA
1 stop12h 14m
Frontier
Thu 4/238:58 pm
OMA
-
SFO
1 stop5h 29m
Frontier
Deal found 3/7$211
This Frontier deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:00 am
SFO
-
DSM
1 stop11h 26m
Frontier
Wed 6/38:21 pm
DSM
-
SFO
1 stop6h 05m
Frontier
Deal found 3/8$211
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/157:40 pm
SFO
-
OMA
2 stops22h 33m
Frontier
Mon 4/208:58 pm
OMA
-
SFO
1 stop28h 27m
Frontier
Deal found 3/7$213
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/269:00 pm
SFO
-
DSM
1 stop13h 59m
Multiple Airlines
Sun 5/3110:26 pm
DSM
-
SFO
1 stop17h 03m
Multiple Airlines
Deal found 3/8$228
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/269:00 pm
SFO
-
DSM
1 stop13h 59m
Multiple Airlines
Mon 6/19:17 pm
DSM
-
SFO
1 stop18h 12m
Multiple Airlines
Deal found 3/8$229
This Frontier deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2011:56 am
SFO
-
OMA
1 stop6h 17m
Frontier
Fri 4/248:49 pm
OMA
-
SFO
1 stop5h 38m
Frontier
Deal found 3/9$231
This Frontier deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:00 am
SFO
-
OMA
1 stop12h 04m
Frontier
Thu 4/238:58 pm
OMA
-
SFO
1 stop5h 29m
Frontier
Deal found 3/9$232
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:00 am
SFO
-
DSM
1 stop11h 26m
Multiple Airlines
Sun 5/3110:26 pm
DSM
-
SFO
1 stop17h 03m
Multiple Airlines
Deal found 3/8$233
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:00 am
SFO
-
OMA
1 stop12h 14m
Frontier
Thu 4/168:58 pm
OMA
-
SFO
1 stop29h 29m
Frontier
Deal found 3/10$234

Find flight deals from San Francisco to Iowa

Keep the following information in mind while searching for San Francisco to Iowa flight deals. Data was last updated March 12, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$190
(Expedia)

One-way from

$91
(Trip.com)

Popular in

January

Cheapest in

February

Average price

$613
Provider with most accurate pricing for San Francisco-Des Moines flight deals.
Provider most trusted by Cheapflights users for San Francisco-Des Moines flights.
From San Francisco to Iowa
One-way flight from San Francisco to Iowa
Highest demand for flights based on searches. 10% potential increase in price ($58 potential increase over avg. RT price).
Cheapest flight prices on average. 7% potential price decrease ($34 potential savings vs. average RT price).
Average for round-trip flights in March 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 12, 2026.
Use the filters below to find and compare flights from San Francisco to Iowa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San FranciscoOmaha

SFO - OMA

SFOOMA

San Francisco

Tue 4/7

6:40 am-4:20 pm

1 stop7h 40m

Omaha Eppley Airfield

Tue 4/14

7:23 am-9:30 am

Nonstop4h 07m

$279
Quickest round-trip

San FranciscoOmaha

SFO - OMA

SFOOMA

San Francisco

Sat 7/4

6:45 pm-12:19 am

Nonstop3h 34m

Omaha Eppley Airfield

Thu 7/9

7:38 am-9:28 am

Nonstop3h 50m

$306

San FranciscoLa Crosse

SFO - LSE

SFOLSE

San Francisco

Fri 5/8

10:55 pm-9:06 am

1 stop8h 11m

La Crosse

Tue 5/12

7:26 pm-12:50 am

1 stop7h 24m

$338

San FranciscoLa Crosse

SFO - LSE

SFOLSE

San Francisco

Fri 5/8

6:40 pm-9:35 am

2 stops12h 55m

La Crosse

Tue 5/12

6:37 pm-11:59 pm

1 stop7h 22m

$344

San FranciscoOmaha

SFO - OMA

SFOOMA

San Francisco

Tue 6/16

6:15 am-4:24 pm

1 stop8h 09m

Omaha Eppley Airfield

Wed 6/24

7:38 am-9:28 am

Nonstop3h 50m

$354

San FranciscoOmaha

SFO - OMA

SFOOMA

San Francisco

Tue 4/7

5:55 am-3:40 pm

2 stops7h 45m

Omaha Eppley Airfield

Tue 4/14

6:10 pm-11:15 pm

2 stops7h 05m

$363

San FranciscoOmaha

SFO - OMA

SFOOMA

San Francisco

Thu 9/3

6:00 am-12:40 pm

1 stop4h 40m

Omaha Eppley Airfield

Sun 9/6

12:27 pm-11:46 pm

2 stops13h 19m

$370

San FranciscoMoline

SFO - MLI

SFOMLI

San Francisco

Tue 8/25

12:15 pm-11:22 pm

2 stops9h 07m

Moline Quad-City

Sun 8/30

6:00 am-1:06 pm

2 stops9h 06m

$379

San FranciscoDes Moines

SFO - DSM

SFODSM

San Francisco

Wed 4/15

5:00 am-12:47 pm

1 stop5h 47m

Des Moines

Tue 4/21

5:12 pm-10:55 pm

1 stop7h 43m

$379

San FranciscoDes Moines

SFO - DSM

SFODSM

San Francisco

Tue 4/7

8:20 am-4:10 pm

1 stop5h 50m

Des Moines

Sat 4/11

5:30 am-9:30 am

1 stop6h 00m

$379

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/8

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from San Francisco to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Iowa

What is the cheapest month to book a flight from San Francisco to Iowa?

Currently, September is the cheapest month in which you can book a flight from San Francisco to Iowa (average of $149). Flying from San Francisco to Iowa in January is currently the most expensive (average of $314). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated March 12, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from San Francisco to Iowa have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

8.1

Entertainment

7.5

Food

7.0

Overall

8.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Boarding

8.1

Entertainment

7.5

Food

7.0

Overall

8.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Boarding

8.1

Entertainment

7.5

Food

7.0

Overall

8.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Boarding

8.1

Entertainment

7.5

Food

7.0

Overall

8.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Boarding

8.1

Entertainment

7.5

Food

7.0

Overall

8.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Boarding

8.1

Entertainment

7.5

Food

7.0

Overall

8.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from San Francisco to Iowa?

    Most people fly from San Francisco (SFO) if they book a flight from San Francisco to Iowa. San Francisco is conveniently located just 11.8 mi from San Francisco’s city center.

  • How long is the flight from San Francisco to Iowa?

    For as low as $279, United Airlines can have you in Iowa from San Francisco in 7h 40m. There are 1429 mi between San Francisco and Iowa. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from San Francisco to Iowa one-way?

    $98 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on Delta and American Airlines, with prices starting from $128 and $156, respectively.

  • What are the most popular routes from San Francisco to Iowa?

  • Can I find deals for flights from San Francisco to Iowa that include hotel bookings?

    Yes. In addition to deals on San Francisco to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Iowa.

  • Can I find deals for business class flights from San Francisco to Iowa?

    Yes. Cheapflights offers flight deals from San Francisco to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Iowa?

    Currently, September is the cheapest month in which you can book a flight from San Francisco to Iowa (average of $149). Flying from San Francisco to Iowa in January is currently the most expensive (average of $314). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for San Francisco to Iowa

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from San Francisco to Iowa

Discover the top 5 airlines that operate flights from San Francisco to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$149Average$285FlexibilityNo cancel feeOn-time62%
DeltaCheapest$256Average$416FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$288Average$477FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$301Average$595FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$346Average$426FlexibilityNo cancel feeOn-time63%

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