Iowa

$98+ Cheap flights from San Francisco (SFO) to Iowa

SFO — DSM
Dec 6 — Dec 131
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Cheap flight deals from San Francisco to Iowa

Cheapest flights from San Francisco to Iowa

Thu 12/39:06 pm -
1 stop21h 22m
Thu 12/108:39 pm -
1 stop15h 00m
Deal found 11/5$242
Thu 12/106:30 am -
1 stop11h 12m
Thu 12/178:26 pm -
1 stop6h 09m
Deal found 11/5$245
Thu 12/176:15 am -
1 stop11h 16m
Sun 1/1010:07 pm -
1 stop17h 15m
Deal found 11/4$247
Thu 12/39:06 pm -
1 stop21h 22m
Sun 12/63:15 pm -
1 stop22h 11m
Deal found 11/5$248
Wed 12/239:23 pm -
1 stop20h 08m
Sun 1/1010:07 pm -
2 stops14h 57m
Deal found 11/4$257
Wed 12/239:23 pm -
1 stop20h 08m
Mon 1/111:57 pm -
1 stop20h 51m
Deal found 11/4$264
Thu 12/1711:23 am -
1 stop6h 08m
Mon 1/1111:12 am -
2 stops15h 23m
Deal found 11/4$265
Wed 11/259:23 pm -
1 stop20h 10m
Mon 11/309:39 pm -
1 stop14h 01m
Deal found 11/3$266
Thu 12/176:15 am -
1 stop11h 16m
Thu 1/78:17 pm -
1 stop6h 18m
Deal found 11/4$270
Thu 12/176:00 pm -
1 stop23h 28m
Sat 1/912:53 pm -
1 stop29h 03m
Deal found 11/5$332
Fri 12/1810:21 pm -
2 stops35h 15m
Sat 1/912:53 pm -
1 stop29h 03m
Deal found 11/5$377
Thu 12/1712:30 am -
1 stop7h 39m
Sat 1/98:49 am -
1 stop6h 26m
Deal found 11/3$379

Find flight deals from San Francisco to Iowa

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$205
(Kiwi.com)

One-way from

$98
(Kiwi.com)

Popular in

January

Cheapest in

February

Average price

$578
Provider with most accurate pricing for San Francisco-Des Moines flight deals.
Provider most trusted by Cheapflights users for San Francisco-Des Moines flights.
From San Francisco to Iowa
One-way flight from San Francisco to Iowa
High demand for flights, 5% potential price rise
Cheapest flight prices on average. 4% potential price decrease ($26 potential savings vs. average RT price).
Average for round-trip flights in November 2026

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from San Francisco to Iowa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San FranciscoDes Moines

SFO San Francisco - DSM Des Moines

SFODSM

San Francisco

Thu 12/3

9:06 pm-8:28 pm

1 stop21h 22m

Des Moines

Wed 12/31

12:00 am-10:00 pm

Nonstop0h 00m

$98

San FranciscoDes Moines

SFO San Francisco - DSM Des Moines

SFODSM

San Francisco

Sun 12/20

6:15 am-7:31 pm

1 stop11h 16m

Des Moines

Wed 12/31

12:00 am-10:00 pm

Nonstop0h 00m

$162

San FranciscoDes Moines

SFO San Francisco - DSM Des Moines

SFODSM

San Francisco

Sun 12/13

4:33 pm-2:50 pm

2 stops44h 17m

Des Moines

Wed 12/31

12:00 am-10:00 pm

Nonstop0h 00m

$177

San FranciscoCedar Rapids

SFO San Francisco - CID Cedar Rapids

SFOCID

San Francisco

Tue 12/22

10:21 pm-11:04 am

2 stops34h 43m

Cedar Rapids

Wed 12/31

12:00 am-10:00 pm

Nonstop0h 00m

$181

San FranciscoCedar Rapids

SFO San Francisco - CID Cedar Rapids

SFOCID

San Francisco

Wed 12/23

9:46 pm-11:04 am

1 stop11h 18m

Cedar Rapids

Wed 12/31

12:00 am-10:00 pm

Nonstop0h 00m

$184

San FranciscoDes Moines

SFO San Francisco - DSM Des Moines

SFODSM

San Francisco

Wed 12/9

9:59 pm-10:53 am

1 stop10h 54m

Des Moines

Wed 12/31

12:00 am-10:00 pm

Nonstop0h 00m

$185

San FranciscoDes Moines

SFO San Francisco - DSM Des Moines

SFODSM

San Francisco

Thu 12/3

12:41 pm-9:25 pm

1 stop6h 44m

Des Moines

Wed 12/31

12:00 am-10:00 pm

Nonstop0h 00m

$185

San FranciscoDes Moines

SFO San Francisco - DSM Des Moines

SFODSM

San Francisco

Mon 11/23

5:00 am-2:26 pm

1 stop7h 26m

Des Moines

Wed 12/31

12:00 am-10:00 pm

Nonstop0h 00m

$185

San FranciscoCedar Rapids

SFO San Francisco - CID Cedar Rapids

SFOCID

San Francisco

Thu 11/12

10:23 pm-11:55 am

1 stop11h 32m

Cedar Rapids

Wed 12/31

12:00 am-10:00 pm

Nonstop0h 00m

$187

San FranciscoDes Moines

SFO San Francisco - DSM Des Moines

SFODSM

San Francisco

Thu 12/3

10:25 am-8:50 pm

2 stops8h 25m

Des Moines

Wed 12/31

12:00 am-10:00 pm

Nonstop0h 00m

$190

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/5

Showing 1-10 of 48 resultsSorted by cheapest first
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Best time to book a flight from San Francisco to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from San Francisco with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Iowa

What is the cheapest month to book a flight from San Francisco to Iowa?

Currently, February is the cheapest month in which you can book a flight from San Francisco to Iowa (average of $305). Flying from San Francisco to Iowa in May is currently the most expensive (average of $631). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from San Francisco to Iowa?

Airfare is below average for this route at the moment.
San Francisco to Iowa flights typically cost between $467 and $729 in January.
The cheapest round-trip price found within the last 5 days was $205 on Multiple Airlines (Jan 8-Jan 11).

How far ahead should I book a flight from San Francisco to Iowa?

The best time to book flights from San Francisco to Iowa is 27 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

Reviews of airlines servicing Iowa

See what other customers who have flown with Southwest,Delta, andUnited Airlines from San Francisco to Iowa have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

La Tracimeldamarcos,Jun 2026

LAX - SLC

The second flight was not as comfortable as the first as we had to change planes to what seemed to be a slightly older aircraft. The seats weren’t as comfortable as the other plane. But it wasn’t bad.

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

La Tracimeldamarcos,Jun 2026

LAX - SLC

The second flight was not as comfortable as the first as we had to change planes to what seemed to be a slightly older aircraft. The seats weren’t as comfortable as the other plane. But it wasn’t bad.

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

La Tracimeldamarcos,Jun 2026

LAX - SLC

The second flight was not as comfortable as the first as we had to change planes to what seemed to be a slightly older aircraft. The seats weren’t as comfortable as the other plane. But it wasn’t bad.

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

La Tracimeldamarcos,Jun 2026

LAX - SLC

The second flight was not as comfortable as the first as we had to change planes to what seemed to be a slightly older aircraft. The seats weren’t as comfortable as the other plane. But it wasn’t bad.

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

La Tracimeldamarcos,Jun 2026

LAX - SLC

The second flight was not as comfortable as the first as we had to change planes to what seemed to be a slightly older aircraft. The seats weren’t as comfortable as the other plane. But it wasn’t bad.

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

La Tracimeldamarcos,Jun 2026

LAX - SLC

The second flight was not as comfortable as the first as we had to change planes to what seemed to be a slightly older aircraft. The seats weren’t as comfortable as the other plane. But it wasn’t bad.

Related info for your journey

  • What airport do you fly from for flights from San Francisco to Iowa?

    Most people fly from San Francisco (SFO) if they book a flight from San Francisco to Iowa. San Francisco is conveniently located just 11.0 mi from San Francisco’s city center.

  • How long is the flight from San Francisco to Iowa?

    For as low as $379, Delta can have you in Iowa from San Francisco in 7h 39m. There are 1645 mi between San Francisco and Iowa. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from San Francisco to Iowa one-way?

    $111 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on American Airlines and Southwest, with prices starting from $181 and $181, respectively.

  • What are the most popular routes from San Francisco to Iowa?

  • Can I find deals for flights from San Francisco to Iowa that include hotel bookings?

    Yes. In addition to deals on San Francisco to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Iowa.

  • Can I find deals for business class flights from San Francisco to Iowa?

    Yes. Cheapflights offers flight deals from San Francisco to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Iowa?

    Currently, February is the cheapest month in which you can book a flight from San Francisco to Iowa (average of $305). Flying from San Francisco to Iowa in May is currently the most expensive (average of $631). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for San Francisco to Iowa

Top 5 airlines flying from San Francisco to Iowa

AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$230Average$329FlexibilityNo cancel feeOn-time62%
DeltaCheapest$325Average$541FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$326Average$527FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$328Average$688FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$358Average$449FlexibilityNo cancel feeOn-time63%

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